-
1
-
-
60849105360
-
International epidemiology of prostate cancer: Geographical distribution and secular trends
-
P.D. Baade, D.R. Youlden, and L.J. Krnjacki International epidemiology of prostate cancer: geographical distribution and secular trends Mol Nutr Food Res 53 2 2009 171 184
-
(2009)
Mol Nutr Food Res
, vol.53
, Issue.2
, pp. 171-184
-
-
Baade, P.D.1
Youlden, D.R.2
Krnjacki, L.J.3
-
2
-
-
80051580618
-
Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
R. Siegel, E. Ward, O. Brawley, and A. Jemal Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths CA Cancer J Clin 61 4 2011 212 236
-
(2011)
CA Cancer J Clin
, vol.61
, Issue.4
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
Jemal, A.4
-
3
-
-
85006768050
-
The metabolism of tumors in the body
-
O. Warburg, F. Wind, and E. Negelein The metabolism of tumors in the body J Gen Physiol 8 6 1927 519 530
-
(1927)
J Gen Physiol
, vol.8
, Issue.6
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
4
-
-
0028301959
-
Fatty acid synthesis: A potential selective target for antineoplastic therapy
-
DOI 10.1073/pnas.91.14.6379
-
F.P. Kuhajda, K. Jenner, F.D. Wood, R.A. Hennigar, L.B. Jacobs, and J.D. Dick Fatty acid synthesis: a potential selective target for antineoplastic therapy Proc Natl Acad Sci U S A 91 14 1994 6379 6383 (Pubitemid 24200664)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.14
, pp. 6379-6383
-
-
Kuhajda, F.P.1
Jenner, K.2
Wood, F.D.3
Hennigar, R.A.4
Jacobs, L.B.5
Dick, J.D.6
Pasternack, G.R.7
-
5
-
-
0029051666
-
Human fatty acid synthase: Properties and molecular cloning
-
A. Jayakumar, M.H. Tai, W.Y. Huang, W. Al-Feel, M. Hsu, and L. Abu-Elheiga Human fatty acid synthase: properties and molecular cloning Proc Natl Acad Sci U S A 92 19 1995 8695 8699
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, Issue.19
, pp. 8695-8699
-
-
Jayakumar, A.1
Tai, M.H.2
Huang, W.Y.3
Al-Feel, W.4
Hsu, M.5
Abu-Elheiga, L.6
-
6
-
-
0029130784
-
Human fatty acid synthase mRNA: Tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation
-
C.F. Semenkovich, T. Coleman, and F.T. Fiedorek Jr. Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation J Lipid Res 36 7 1995 1507 1521
-
(1995)
J Lipid Res
, vol.36
, Issue.7
, pp. 1507-1521
-
-
Semenkovich, C.F.1
Coleman, T.2
Fiedorek, Jr.F.T.3
-
7
-
-
0012249041
-
Metabolism of neoplastic tissue IV. A study of lipid synthesis in neoplastic tissue slices in vitro
-
G. Medes, A. Thomas, and S. Weinhouse Metabolism of neoplastic tissue IV. A study of lipid synthesis in neoplastic tissue slices in vitro Cancer Res 13 1 1953 27 29
-
(1953)
Cancer Res
, vol.13
, Issue.1
, pp. 27-29
-
-
Medes, G.1
Thomas, A.2
Weinhouse, S.3
-
8
-
-
33645114908
-
Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma
-
U.S. Shah, R. Dhir, S.M. Gollin, U.R. Chandran, D. Lewis, and M. Acquafondata Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma Hum Pathol 37 4 2006 401 409
-
(2006)
Hum Pathol
, vol.37
, Issue.4
, pp. 401-409
-
-
Shah, U.S.1
Dhir, R.2
Gollin, S.M.3
Chandran, U.R.4
Lewis, D.5
Acquafondata, M.6
-
9
-
-
0034718771
-
Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
-
J.V. Swinnen, H. Heemers, L. Deboel, F. Foufelle, W. Heyns, and G. Verhoeven Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway Oncogene 19 45 2000 5173 5181
-
(2000)
Oncogene
, vol.19
, Issue.45
, pp. 5173-5181
-
-
Swinnen, J.V.1
Heemers, H.2
Deboel, L.3
Foufelle, F.4
Heyns, W.5
Verhoeven, G.6
-
10
-
-
0030936232
-
Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP
-
J.V. Swinnen, M. Esquenet, K. Goossens, W. Heyns, and G. Verhoeven Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP Cancer Res 57 6 1997 1086 1090 (Pubitemid 27138606)
-
(1997)
Cancer Research
, vol.57
, Issue.6
, pp. 1086-1090
-
-
Swinnen, J.V.1
Esquenet, M.2
Goossens, K.3
Heyns, W.4
Verhoeven, G.5
-
11
-
-
0033814153
-
Selective activation of the fatty acid synthesis pathway in human prostate cancer
-
J.V. Swinnen, F. Vanderhoydonc, A.A. Elgamal, M. Eelen, I. Vercaeren, and S. Joniau Selective activation of the fatty acid synthesis pathway in human prostate cancer Int J Cancer 88 2 2000 176 179
-
(2000)
Int J Cancer
, vol.88
, Issue.2
, pp. 176-179
-
-
Swinnen, J.V.1
Vanderhoydonc, F.2
Elgamal, A.A.3
Eelen, M.4
Vercaeren, I.5
Joniau, S.6
-
12
-
-
0036497907
-
Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer
-
DOI 10.1002/ijc.10127
-
J.V. Swinnen, T. Roskams, S. Joniau, H. Van Poppel, R. Oyen, and L. Baert Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer Int J Cancer 98 1 2002 19 22 (Pubitemid 34113412)
-
(2002)
International Journal of Cancer
, vol.98
, Issue.1
, pp. 19-22
-
-
Swinnen, J.V.1
Roskams, T.2
Joniau, S.3
Van Poppel, H.4
Oyen, R.5
Baert, L.6
Heyns, W.7
Verhoeven, G.8
-
13
-
-
12144286902
-
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
-
DOI 10.1016/S1535-6108(04)00055-8, PII S1535610804000558
-
E. Graner, D. Tang, S. Rossi, A. Baron, T. Migita, and L.J. Weinstein The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer Cancer Cell 5 3 2004 253 261 (Pubitemid 38402117)
-
(2004)
Cancer Cell
, vol.5
, Issue.3
, pp. 253-261
-
-
Graner, E.1
Tang, D.2
Rossi, S.3
Baron, A.4
Migita, T.5
Weinstein, L.J.6
Lechpammer, M.7
Huesken, D.8
Zimmermann, J.9
Signoretti, S.10
Loda, M.11
-
14
-
-
10744222860
-
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
-
DOI 10.1016/S1535-6108(03)00215-0
-
S. Wang, J. Gao, Q. Lei, N. Rozengurt, C. Pritchard, and J. Jiao Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer Cancer Cell 4 3 2003 209 221 (Pubitemid 37163835)
-
(2003)
Cancer Cell
, vol.4
, Issue.3
, pp. 209-221
-
-
Wang, S.1
Gao, J.2
Lei, Q.3
Rozengurt, N.4
Pritchard, C.5
Jiao, J.6
Thomas, G.V.7
Li, G.8
Roy-Burman, P.9
Nelson, P.S.10
Liu, X.11
Wu, H.12
-
15
-
-
42049113832
-
Lkb1 deficiency causes prostate neoplasia in the mouse
-
DOI 10.1158/0008-5472.CAN-07-5169
-
H.B. Pearson, A. McCarthy, C.M. Collins, A. Ashworth, and A.R. Clarke Lkb1 deficiency causes prostate neoplasia in the mouse Cancer Res 68 7 2008 2223 2232 (Pubitemid 351521795)
-
(2008)
Cancer Research
, vol.68
, Issue.7
, pp. 2223-2232
-
-
Pearson, H.B.1
McCarthy, A.2
Collins, C.M.P.3
Ashworth, A.4
Clarke, A.R.5
-
16
-
-
19944398464
-
High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB
-
DOI 10.1002/path.1760
-
T. Van de Sande, T. Roskams, E. Lerut, S. Joniau, H. Van Poppel, and G. Verhoeven High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB J Pathol 206 2 2005 214 219 (Pubitemid 40754025)
-
(2005)
Journal of Pathology
, vol.206
, Issue.2
, pp. 214-219
-
-
Van De Sande, T.1
Roskams, T.2
Lerut, E.3
Joniau, S.4
Van Poppel, H.5
Verhoeven, G.6
Swinnen, J.V.7
-
17
-
-
63649099458
-
Fatty acid synthase: A metabolic enzyme and candidate oncogene in prostate cancer
-
T. Migita, S. Ruiz, A. Fornari, M. Fiorentino, C. Priolo, and G. Zadra Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer J Natl Cancer Inst 101 7 2009 519 532
-
(2009)
J Natl Cancer Inst
, vol.101
, Issue.7
, pp. 519-532
-
-
Migita, T.1
Ruiz, S.2
Fornari, A.3
Fiorentino, M.4
Priolo, C.5
Zadra, G.6
-
18
-
-
0037088683
-
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
-
DOI 10.1074/jbc.M111421200
-
G. Liang, J. Yang, J.D. Horton, R.E. Hammer, J.L. Goldstein, and M.S. Brown Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c J Biol Chem 277 11 2002 9520 9528 (Pubitemid 34953041)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 9520-9528
-
-
Liang, G.1
Yang, J.2
Horton, J.D.3
Hammer, R.E.4
Goldstein, J.L.5
Brown, M.S.6
-
19
-
-
84862908756
-
Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells
-
W.C. Huang, X. Li, J. Liu, J. Lin, and L.W. Chung Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells Mol Cancer Res 10 1 2012 133 142
-
(2012)
Mol Cancer Res
, vol.10
, Issue.1
, pp. 133-142
-
-
Huang, W.C.1
Li, X.2
Liu, J.3
Lin, J.4
Chung, L.W.5
-
20
-
-
0030706079
-
Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
-
L.Z. Milgraum, L.A. Witters, G.R. Pasternack, and F.P. Kuhajda Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma Clin Cancer Res 3 11 1997 2115 2120 (Pubitemid 27505140)
-
(1997)
Clinical Cancer Research
, vol.3
, Issue.11
, pp. 2115-2120
-
-
Milgraum, L.Z.1
Witters, L.A.2
Pasternack, G.R.3
Kuhajda, F.P.4
-
21
-
-
0031007392
-
Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival
-
DOI 10.1016/S0046-8177(97)90177-5
-
T.S. Gansler, W. Hardman 3rd, D.A. Hunt, S. Schaffel, and R.A. Hennigar Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival Hum Pathol 28 6 1997 686 692 (Pubitemid 27258421)
-
(1997)
Human Pathology
, vol.28
, Issue.6
, pp. 686-692
-
-
Gansler, T.S.1
Hardman III, W.2
Hunt, D.A.3
Schaffel, S.4
Hennigar, R.A.5
-
22
-
-
0031021649
-
Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia
-
A. Rashid, E.S. Pizer, M. Moga, L.Z. Milgraum, M. Zahurak, and G.R. Pasternack Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia Am J Pathol 150 1 1997 201 208 (Pubitemid 27027110)
-
(1997)
American Journal of Pathology
, vol.150
, Issue.1
, pp. 201-208
-
-
Rashid, A.1
Pizer, E.S.2
Moga, M.3
Milgraum, L.Z.4
Zahurak, M.5
Pasternack, G.R.6
Kuhajda, F.P.7
Hamilton, S.R.8
-
23
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
DOI 10.1038/nrc2222, PII NRC2222
-
J.A. Menendez, and R. Lupu Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis Nat Rev Cancer 7 10 2007 763 777 (Pubitemid 47469806)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.10
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
24
-
-
0034002793
-
Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
-
DOI 10.1016/S0899-9007(99)00266-X, PII S089990079900266X
-
F.P. Kuhajda Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology Nutrition 16 3 2000 202 208 (Pubitemid 30114274)
-
(2000)
Nutrition
, vol.16
, Issue.3
, pp. 202-208
-
-
Kuhajda, F.P.1
-
25
-
-
33746291023
-
Increased lipogenesis in cancer cells: New players, novel targets
-
DOI 10.1097/01.mco.0000232894.28674.30, PII 0007519720060700000005
-
J.V. Swinnen, K. Brusselmans, and G. Verhoeven Increased lipogenesis in cancer cells: new players, novel targets Curr Opin Clin Nutr Metab Care 9 4 2006 358 365 (Pubitemid 44101970)
-
(2006)
Current Opinion in Clinical Nutrition and Metabolic Care
, vol.9
, Issue.4
, pp. 358-365
-
-
Swinnen, J.V.1
Brusselmans, K.2
Verhoeven, G.3
-
26
-
-
77953471622
-
Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice
-
V. Fritz, Z. Benfodda, G. Rodier, C. Henriquet, F. Iborra, and C. Avances Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice Mol Cancer Ther 9 6 2010 1740 1754
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.6
, pp. 1740-1754
-
-
Fritz, V.1
Benfodda, Z.2
Rodier, G.3
Henriquet, C.4
Iborra, F.5
Avances, C.6
-
27
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
DOI 10.1016/j.ccr.2005.09.008, PII S1535610805003016
-
G. Hatzivassiliou, F. Zhao, D.E. Bauer, C. Andreadis, A.N. Shaw, and D. Dhanak ATP citrate lyase inhibition can suppress tumor cell growth Cancer Cell 8 4 2005 311 321 (Pubitemid 41443416)
-
(2005)
Cancer Cell
, vol.8
, Issue.4
, pp. 311-321
-
-
Hatzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
Andreadis, C.4
Shaw, A.N.5
Dhanak, D.6
Hingorani, S.R.7
Tuveson, D.A.8
Thompson, C.B.9
-
28
-
-
1542720382
-
Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity
-
DOI 10.1158/0008-5472.CAN-03-3645
-
S.J. Kridel, F. Axelrod, N. Rozenkrantz, and J.W. Smith Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity Cancer Res 64 6 2004 2070 2075 (Pubitemid 38339455)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 2070-2075
-
-
Kridel, S.J.1
Axelrod, F.2
Rozenkrantz, N.3
Smith, J.W.4
-
29
-
-
23044482013
-
RNA interference-mediated silencing of the acetyl-Coa-carboxylase-α gene induces growth inhibition and apoptosis of prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-05-0571
-
K. Brusselmans, E. De Schrijver, G. Verhoeven, and J.V. Swinnen RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells Cancer Res 65 15 2005 6719 6725 (Pubitemid 41060709)
-
(2005)
Cancer Research
, vol.65
, Issue.15
, pp. 6719-6725
-
-
Brusselmans, K.1
De Schrijver, E.2
Verhoeven, G.3
Swinnen, J.V.4
-
30
-
-
0038418257
-
RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells
-
E. De Schrijver, K. Brusselmans, W. Heyns, G. Verhoeven, and J.V. Swinnen RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells Cancer Res 63 13 2003 3799 3804 (Pubitemid 36793069)
-
(2003)
Cancer Research
, vol.63
, Issue.13
, pp. 3799-3804
-
-
De Schrijver, E.1
Brusselmans, K.2
Heyns, W.3
Verhoeven, G.4
Swinnen, J.V.5
-
31
-
-
34548580317
-
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells
-
DOI 10.1158/0008-5472.CAN-07-0389
-
A. Beckers, S. Organe, L. Timmermans, K. Scheys, A. Peeters, and K. Brusselmans Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells Cancer Res 67 17 2007 8180 8187 (Pubitemid 47395154)
-
(2007)
Cancer Research
, vol.67
, Issue.17
, pp. 8180-8187
-
-
Beckers, A.1
Organe, S.2
Timmermans, L.3
Scheys, K.4
Peeters, A.5
Brusselmans, K.6
Verhoeven, G.7
Swinnen, J.V.8
-
32
-
-
0344838439
-
Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains
-
DOI 10.1016/S0006-291X(03)00265-1
-
J.V. Swinnen, P.P. Van Veldhoven, L. Timmermans, E. De Schrijver, K. Brusselmans, and F. Vanderhoydonc Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains Biochem Biophys Res Commun 302 4 2003 898 903 (Pubitemid 36294061)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.302
, Issue.4
, pp. 898-903
-
-
Swinnen, J.V.1
Van Veldhoven, P.P.2
Timmermans, L.3
De Schrijver, E.4
Brusselmans, K.5
Vanderhoydonc, F.6
Van De Sande, T.7
Heemers, H.8
Heyns, W.9
Verhoeven, G.10
-
33
-
-
79953236295
-
Lipid-dependent gating of a voltage-gated potassium channel
-
H. Zheng, W. Liu, L.Y. Anderson, and Q.X. Jiang Lipid-dependent gating of a voltage-gated potassium channel Nat Commun 2 2011 250
-
(2011)
Nat Commun
, vol.2
, pp. 250
-
-
Zheng, H.1
Liu, W.2
Anderson, L.Y.3
Jiang, Q.X.4
-
34
-
-
12444252156
-
Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice
-
DOI 10.1038/sj.onc.1208174
-
P.M. Alli, M.L. Pinn, E.M. Jaffee, J.M. McFadden, and F.P. Kuhajda Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice Oncogene 24 1 2005 39 46 (Pubitemid 40143863)
-
(2005)
Oncogene
, vol.24
, Issue.1
, pp. 39-46
-
-
Alli, P.M.1
Finn, M.L.2
Jaffee, E.M.3
McFadden, J.M.4
Kuhajda, F.P.5
-
35
-
-
78049307002
-
De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation
-
E. Rysman, K. Brusselmans, K. Scheys, L. Timmermans, R. Derua, and S. Munck De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation Cancer Res 70 20 2011 8117 8126
-
(2011)
Cancer Res
, vol.70
, Issue.20
, pp. 8117-8126
-
-
Rysman, E.1
Brusselmans, K.2
Scheys, K.3
Timmermans, L.4
Derua, R.5
Munck, S.6
-
36
-
-
56649086770
-
Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer
-
M. Fiorentino, G. Zadra, E. Palescandolo, G. Fedele, D. Bailey, and C. Fiore Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer Lab Invest 88 12 2008 1340 1348
-
(2008)
Lab Invest
, vol.88
, Issue.12
, pp. 1340-1348
-
-
Fiorentino, M.1
Zadra, G.2
Palescandolo, E.3
Fedele, G.4
Bailey, D.5
Fiore, C.6
-
37
-
-
68149098866
-
Identification of a physiologically relevant endogenous ligand for PPARalpha in liver
-
M.V. Chakravarthy, I.J. Lodhi, L. Yin, R.R. Malapaka, H.E. Xu, and J. Turk Identification of a physiologically relevant endogenous ligand for PPARalpha in liver Cell 138 3 2009 476 488
-
(2009)
Cell
, vol.138
, Issue.3
, pp. 476-488
-
-
Chakravarthy, M.V.1
Lodhi, I.J.2
Yin, L.3
Malapaka, R.R.4
Xu, H.E.5
Turk, J.6
-
38
-
-
0242694902
-
Fatty Acid Synthase Inhibition Triggers Apoptosis during S Phase in Human Cancer Cells
-
W. Zhou, P.J. Simpson, J.M. McFadden, C.A. Townsend, S.M. Medghalchi, and A. Vadlamudi Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells Cancer Res 63 21 2003 7330 7337 (Pubitemid 37413474)
-
(2003)
Cancer Research
, vol.63
, Issue.21
, pp. 7330-7337
-
-
Zhou, W.1
Simpson, P.J.2
McFadden, J.M.3
Townsend, C.A.4
Medghalchi, S.M.5
Vadlamudi, A.6
Pinn, M.L.7
Ronnett, G.V.8
Kuhajda, F.P.9
-
39
-
-
0038714272
-
Isozymes of mammalian hexokinase: Structure, subcellular localization and metabolic function
-
DOI 10.1242/jeb.00241
-
J.E. Wilson Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function J Exp Biol 206 Pt 12 2003 2049 2057 (Pubitemid 36761808)
-
(2003)
Journal of Experimental Biology
, vol.206
, Issue.12
, pp. 2049-2057
-
-
Wilson, J.E.1
-
40
-
-
33746924468
-
Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
-
DOI 10.1038/sj.onc.1209603, PII 1209603
-
S.P. Mathupala, Y.H. Ko, and P.L. Pedersen Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria Oncogene 25 34 2006 4777 4786 (Pubitemid 44187625)
-
(2006)
Oncogene
, vol.25
, Issue.34
, pp. 4777-4786
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
41
-
-
79551469518
-
Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase 2 in prostate cancer cells
-
J.S. Moon, W.J. Jin, J.H. Kwak, H.J. Kim, M.J. Yun, and J.W. Kim Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells Biochem J 433 1 2011 225 233
-
(2011)
Biochem J
, vol.433
, Issue.1
, pp. 225-233
-
-
Moon, J.S.1
Jin, W.J.2
Kwak, J.H.3
Kim, H.J.4
Yun, M.J.5
Kim, J.W.6
-
42
-
-
23044500915
-
Pyruvate kinase type M2 and its role in tumor growth and spreading
-
DOI 10.1016/j.semcancer.2005.04.009, PII S1044579X0500026X, Tumor Metabolome
-
S. Mazurek, C.B. Boschek, F. Hugo, and E. Eigenbrodt Pyruvate kinase type M2 and its role in tumor growth and spreading Semin Cancer Biol 15 4 2005 300 308 (Pubitemid 41058775)
-
(2005)
Seminars in Cancer Biology
, vol.15
, Issue.4
, pp. 300-308
-
-
Mazurek, S.1
Boschek, C.B.2
Hugo, F.3
Eigenbrodt, E.4
-
43
-
-
0026467983
-
Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells
-
E. Eigenbrodt, M. Reinacher, U. Scheefers-Borchel, H. Scheefers, and R. Friis Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells Crit Rev Oncog 3 1-2 1992 91 115
-
(1992)
Crit Rev Oncog
, vol.3
, Issue.12
, pp. 91-115
-
-
Eigenbrodt, E.1
Reinacher, M.2
Scheefers-Borchel, U.3
Scheefers, H.4
Friis, R.5
-
44
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
DOI 10.1038/nature06734, PII NATURE06734
-
H.R. Christofk, M.G. Vander Heiden, M.H. Harris, A. Ramanathan, R.E. Gerszten, and R. Wei The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth Nature 452 7184 2008 230 233 (Pubitemid 351380249)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
45
-
-
82755166890
-
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
-
D. Anastasiou, G. Poulogiannis, J.M. Asara, M.B. Boxer, J.K. Jiang, and M. Shen Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses Science 334 6060 2011 1278 1283
-
(2011)
Science
, vol.334
, Issue.6060
, pp. 1278-1283
-
-
Anastasiou, D.1
Poulogiannis, G.2
Asara, J.M.3
Boxer, M.B.4
Jiang, J.K.5
Shen, M.6
-
46
-
-
77956674635
-
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
-
M.G. Vander Heiden, J.W. Locasale, K.D. Swanson, H. Sharfi, G.J. Heffron, and D. Amador-Noguez Evidence for an alternative glycolytic pathway in rapidly proliferating cells Science 329 5998 2010 1492 1499
-
(2010)
Science
, vol.329
, Issue.5998
, pp. 1492-1499
-
-
Vander Heiden, M.G.1
Locasale, J.W.2
Swanson, K.D.3
Sharfi, H.4
Heffron, G.J.5
Amador-Noguez, D.6
-
47
-
-
4544312373
-
+-dependent isocitrate dehydrogenase plays a key role in lipid metabolism
-
DOI 10.1074/jbc.M402260200
-
H.J. Koh, S.M. Lee, B.G. Son, S.H. Lee, Z.Y. Ryoo, and K.T. Chang Cytosolic NADP+-dependent isocitrate dehydrogenase plays a key role in lipid metabolism J Biol Chem 279 38 2004 39968 39974 (Pubitemid 39258270)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.38
, pp. 39968-39974
-
-
Koh, H.-J.1
Lee, S.-M.2
Son, B.-G.3
Lee, S.-H.4
Ryoo, Z.Y.5
Chang, K.-T.6
Park, J.-W.7
Park, D.-C.8
Song, B.J.9
Veech, R.L.10
Song, H.11
Huh, T.-L.12
-
48
-
-
77954697566
-
Isocitrate dehydrogenase 1 and 2 mutations in cancer: Alterations at a crossroads of cellular metabolism
-
Z.J. Reitman, and H. Yan Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism J Natl Cancer Inst 102 13 2010 932 941
-
(2010)
J Natl Cancer Inst
, vol.102
, Issue.13
, pp. 932-941
-
-
Reitman, Z.J.1
Yan, H.2
-
49
-
-
77949262337
-
Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer
-
A.K. Murugan, E. Bojdani, and M. Xing Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer Biochem Biophys Res Commun 393 3 2010 555 559
-
(2010)
Biochem Biophys Res Commun
, vol.393
, Issue.3
, pp. 555-559
-
-
Murugan, A.K.1
Bojdani, E.2
Xing, M.3
-
50
-
-
59849124365
-
Citrate transport and metabolism in mammalian cells: Prostate epithelial cells and prostate cancer
-
M.E. Mycielska, A. Patel, N. Rizaner, M.P. Mazurek, H. Keun, and V. Ganapathy Citrate transport and metabolism in mammalian cells: prostate epithelial cells and prostate cancer Bioessays 31 1 2009 10 20
-
(2009)
Bioessays
, vol.31
, Issue.1
, pp. 10-20
-
-
Mycielska, M.E.1
Patel, A.2
Rizaner, N.3
Mazurek, M.P.4
Keun, H.5
Ganapathy, V.6
-
51
-
-
0028302955
-
Isocitric and citric acid in human prostatic and seminal fluid: Implications for prostatic metabolism and secretion
-
J.P. Kavanagh Isocitric and citric acid in human prostatic and seminal fluid: implications for prostatic metabolism and secretion Prostate 24 3 1994 139 142 (Pubitemid 24109594)
-
(1994)
Prostate
, vol.24
, Issue.3
, pp. 139-142
-
-
Kavanagh, J.P.1
-
52
-
-
32944475445
-
Utilization of citrate and lactate through a lactate dehydrogenase and ATP-regulated pathway in boar spermatozoa
-
DOI 10.1002/mrd.20414
-
A. Medrano, J.M. Fernandez-Novell, L. Ramio, J. Alvarez, E. Goldberg, and M. Montserrat Rivera Utilization of citrate and lactate through a lactate dehydrogenase and ATP-regulated pathway in boar spermatozoa Mol Reprod Dev 73 3 2006 369 378 (Pubitemid 43262052)
-
(2006)
Molecular Reproduction and Development
, vol.73
, Issue.3
, pp. 369-378
-
-
Medrano, A.1
Fernandez-Novell, J.M.2
Ramio, L.3
Alvarez, J.4
Goldberg, E.5
Rivera, Ma.M.6
Guinovart, J.J.7
Rigau, T.8
Rodriguez-Gil, J.E.9
-
53
-
-
33746835711
-
Citrate enhances in vitro metastatic behaviours of PC-3M human prostate cancer cells: Status of endogenous citrate and dependence on aconitase and fatty acid synthase
-
DOI 10.1016/j.biocel.2006.04.008, PII S1357272506001506
-
M.E. Mycielska, T.P. Broke-Smith, C.P. Palmer, R. Beckerman, T. Nastos, and K. Erguler Citrate enhances in vitro metastatic behaviours of PC-3M human prostate cancer cells: status of endogenous citrate and dependence on aconitase and fatty acid synthase Int J Biochem Cell Biol 38 10 2006 1766 1777 (Pubitemid 44173018)
-
(2006)
International Journal of Biochemistry and Cell Biology
, vol.38
, Issue.10
, pp. 1766-1777
-
-
Mycielska, M.E.1
Broke-Smith, T.P.2
Palmer, C.P.3
Beckerman, R.4
Nastos, T.5
Erguler, K.6
Djamgoz, M.B.A.7
-
54
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
R.J. DeBerardinis, A. Mancuso, E. Daikhin, I. Nissim, M. Yudkoff, and S. Wehrli Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis Proc Natl Acad Sci U S A 104 49 2007 19345 19350
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.49
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
-
55
-
-
79551634068
-
Differential effects of specific amino acid restriction on glucose metabolism, reduction/oxidation status and mitochondrial damage in DU145 and PC3 prostate cancer cells
-
X. Liu, Y.M. Fu, and G.G. Meadows Differential effects of specific amino acid restriction on glucose metabolism, reduction/oxidation status and mitochondrial damage in DU145 and PC3 prostate cancer cells Oncol Lett 2 2 2011 349 355
-
(2011)
Oncol Lett
, vol.2
, Issue.2
, pp. 349-355
-
-
Liu, X.1
Fu, Y.M.2
Meadows, G.G.3
-
56
-
-
84855987831
-
Reductive carboxylation supports growth in tumour cells with defective mitochondria
-
A.R. Mullen, W.W. Wheaton, E.S. Jin, P.H. Chen, L.B. Sullivan, and T. Cheng Reductive carboxylation supports growth in tumour cells with defective mitochondria Nature 481 7381 2012 385 388
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 385-388
-
-
Mullen, A.R.1
Wheaton, W.W.2
Jin, E.S.3
Chen, P.H.4
Sullivan, L.B.5
Cheng, T.6
-
57
-
-
84856014884
-
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
-
C.M. Metallo, P.A. Gameiro, E.L. Bell, K.R. Mattaini, J. Yang, and K. Hiller Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Nature 481 7381 2012 380 384
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 380-384
-
-
Metallo, C.M.1
Gameiro, P.A.2
Bell, E.L.3
Mattaini, K.R.4
Yang, J.5
Hiller, K.6
-
58
-
-
34250788809
-
AKT/PKB Signaling: Navigating Downstream
-
DOI 10.1016/j.cell.2007.06.009, PII S0092867407007751
-
B.D. Manning, and L.C. Cantley AKT/PKB signaling: navigating downstream Cell 129 7 2007 1261 1274 (Pubitemid 46962095)
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
59
-
-
0031762207
-
Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN
-
I.C. Gray, L.M. Stewart, S.M. Phillips, J.A. Hamilton, N.E. Gray, and G.J. Watson Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN Br J Cancer 78 10 1998 1296 1300 (Pubitemid 28495240)
-
(1998)
British Journal of Cancer
, vol.78
, Issue.10
, pp. 1296-1300
-
-
Gray, I.C.1
Stewart, L.M.D.2
Phillips, S.M.A.3
Hamilton, J.A.4
Gray, N.E.5
Watson, G.J.6
Spurr, N.K.7
Snary, D.8
-
60
-
-
79953803691
-
PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome
-
Y. Li, J. Su, X. DingZhang, J. Zhang, M. Yoshimoto, and S. Liu PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome J Pathol 224 1 2011 90 100
-
(2011)
J Pathol
, vol.224
, Issue.1
, pp. 90-100
-
-
Li, Y.1
Su, J.2
Dingzhang, X.3
Zhang, J.4
Yoshimoto, M.5
Liu, S.6
-
61
-
-
84856530618
-
Common structural and epigenetic changes in the genome of castration-resistant prostate cancer
-
T.W. Friedlander, R. Roy, S.A. Tomlins, V.T. Ngo, Y. Kobayashi, and A. Azameera Common structural and epigenetic changes in the genome of castration-resistant prostate cancer Cancer Res 72 3 2012 616 625
-
(2012)
Cancer Res
, vol.72
, Issue.3
, pp. 616-625
-
-
Friedlander, T.W.1
Roy, R.2
Tomlins, S.A.3
Ngo, V.T.4
Kobayashi, Y.5
Azameera, A.6
-
62
-
-
66149141021
-
PTEN and the PI3-kinase pathway in cancer
-
N. Chalhoub, and S.J. Baker PTEN and the PI3-kinase pathway in cancer Annu Rev Pathol 4 2009 127 150
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 127-150
-
-
Chalhoub, N.1
Baker, S.J.2
-
63
-
-
0036469122
-
Role of the phosphatidylinositol 3′-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells
-
T. Van de Sande, E. De Schrijver, W. Heyns, G. Verhoeven, and J.V. Swinnen Role of the phosphatidylinositol 3′-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells Cancer Res 62 3 2002 642 646 (Pubitemid 34126933)
-
(2002)
Cancer Research
, vol.62
, Issue.3
, pp. 642-646
-
-
Van De Sande, T.1
De Schrijver, E.2
Heyns, W.3
Verhoeven, G.4
Swinnen, J.V.5
-
64
-
-
19944374798
-
Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells
-
DOI 10.1038/sj.onc.1208463
-
H.Q. Wang, D.A. Altomare, K.L. Skele, P.I. Poulikakos, F.P. Kuhajda, and A. Di Cristofano Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells Oncogene 24 22 2005 3574 3582 (Pubitemid 40756227)
-
(2005)
Oncogene
, vol.24
, Issue.22
, pp. 3574-3582
-
-
Wang, H.Q.1
Altomare, D.A.2
Skele, K.L.3
Poulikakos, P.I.4
Kuhajda, F.P.5
Di Cristofano, A.6
Testa, J.R.7
-
65
-
-
84055207483
-
Blockade of fatty acid synthase induces ubiquitination and degradation of phosphoinositide-3-kinase signaling proteins in ovarian cancer
-
K. Tomek, R. Wagner, F. Varga, C.F. Singer, H. Karlic, and T.W. Grunt Blockade of fatty acid synthase induces ubiquitination and degradation of phosphoinositide-3-kinase signaling proteins in ovarian cancer Mol Cancer Res 9 12 2011 1767 1779
-
(2011)
Mol Cancer Res
, vol.9
, Issue.12
, pp. 1767-1779
-
-
Tomek, K.1
Wagner, R.2
Varga, F.3
Singer, C.F.4
Karlic, H.5
Grunt, T.W.6
-
66
-
-
80053426842
-
Targeted therapies for breast cancer
-
M.J. Higgins, and J. Baselga Targeted therapies for breast cancer J Clin Invest 121 10 2011 3797 3803
-
(2011)
J Clin Invest
, vol.121
, Issue.10
, pp. 3797-3803
-
-
Higgins, M.J.1
Baselga, J.2
-
67
-
-
77649108628
-
Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer
-
S. Minner, B. Jessen, L. Stiedenroth, E. Burandt, J. Kollermann, and M. Mirlacher Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer Clin Cancer Res 16 5 2010 1553 1560
-
(2010)
Clin Cancer Res
, vol.16
, Issue.5
, pp. 1553-1560
-
-
Minner, S.1
Jessen, B.2
Stiedenroth, L.3
Burandt, E.4
Kollermann, J.5
Mirlacher, M.6
-
68
-
-
0037226462
-
Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis
-
C. Kumar-Sinha, K.W. Ignatoski, M.E. Lippman, S.P. Ethier, and A.M. Chinnaiyan Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis Cancer Res 63 1 2003 132 139 (Pubitemid 36070431)
-
(2003)
Cancer Research
, vol.63
, Issue.1
, pp. 132-139
-
-
Kumar-Sinha, C.1
Ignatoski, K.W.2
Lippman, M.E.3
Ethier, S.P.4
Chinnaiyan, A.M.5
-
69
-
-
34548814981
-
Up-regulation of acetyl-CoA carboxylase α and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells
-
DOI 10.1074/jbc.M702854200
-
S. Yoon, M.Y. Lee, S.W. Park, J.S. Moon, Y.K. Koh, and Y.H. Ahn Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells J Biol Chem 282 36 2007 26122 26131 (Pubitemid 47443806)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.36
, pp. 26122-26131
-
-
Yoon, S.1
Lee, M.-Y.2
Park, S.W.3
Moon, J.-S.4
Koh, Y.-K.5
Ahn, Y.-H.6
Park, B.-W.7
Kim, K.-S.8
-
70
-
-
40949159866
-
Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype
-
DOI 10.1158/0008-5472.CAN-07-5259
-
B. Kumar, S. Koul, L. Khandrika, R.B. Meacham, and H.K. Koul Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype Cancer Res 68 6 2008 1777 1785 (Pubitemid 351416563)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1777-1785
-
-
Kumar, B.1
Koul, S.2
Khandrika, L.3
Meacham, R.B.4
Koul, H.K.5
-
71
-
-
74449089780
-
Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression
-
M. Shiota, A. Yokomizo, Y. Tada, J. Inokuchi, E. Kashiwagi, and D. Masubuchi Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression Oncogene 29 2 2010 237 250
-
(2010)
Oncogene
, vol.29
, Issue.2
, pp. 237-250
-
-
Shiota, M.1
Yokomizo, A.2
Tada, Y.3
Inokuchi, J.4
Kashiwagi, E.5
Masubuchi, D.6
-
72
-
-
80052270884
-
Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer
-
M. Shiota, A. Yokomizo, and S. Naito Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer Free Radic Biol Med 51 7 2011 1320 1328
-
(2011)
Free Radic Biol Med
, vol.51
, Issue.7
, pp. 1320-1328
-
-
Shiota, M.1
Yokomizo, A.2
Naito, S.3
-
73
-
-
44449140859
-
Mechanisms of ROS modulated cell survival during carcinogenesis
-
J.S. Clerkin, R. Naughton, C. Quiney, and T.G. Cotter Mechanisms of ROS modulated cell survival during carcinogenesis Cancer Lett 266 1 2008 30 36
-
(2008)
Cancer Lett
, vol.266
, Issue.1
, pp. 30-36
-
-
Clerkin, J.S.1
Naughton, R.2
Quiney, C.3
Cotter, T.G.4
-
74
-
-
39549117982
-
Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1
-
DOI 10.1158/0008-5472.CAN-07-2489
-
E. Furuta, S.K. Pai, R. Zhan, S. Bandyopadhyay, M. Watabe, and Y.Y. Mo Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1 Cancer Res 68 4 2008 1003 1011 (Pubitemid 351278386)
-
(2008)
Cancer Research
, vol.68
, Issue.4
, pp. 1003-1011
-
-
Furuta, E.1
Pai, S.K.2
Zhan, R.3
Bandyopadhyay, S.4
Watabe, M.5
Mo, Y.-Y.6
Hirota, S.7
Hosobe, S.8
Tsukada, T.9
Miura, K.10
Kamada, S.11
Saito, K.12
Iiizumi, M.13
Liu, W.14
Ericsson, J.15
Watabe, K.16
-
75
-
-
0042242883
-
NOX5 NAD(P)H oxidase regulates growth and apoptosis in du 145 prostate cancer cells
-
S.S. Brar, Z. Corbin, T.P. Kennedy, R. Hemendinger, L. Thornton, and B. Bommarius NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells Am J Physiol Cell Physiol 285 2 2003 C353 C369
-
(2003)
Am J Physiol Cell Physiol
, vol.285
, Issue.2
-
-
Brar, S.S.1
Corbin, Z.2
Kennedy, T.P.3
Hemendinger, R.4
Thornton, L.5
Bommarius, B.6
-
76
-
-
77950879014
-
Androgen receptor survival signaling is blocked by anti-beta2- microglobulin monoclonal antibody via a MAPK/lipogenic pathway in human prostate cancer cells
-
W.C. Huang, H.E. Zhau, and L.W. Chung Androgen receptor survival signaling is blocked by anti-beta2-microglobulin monoclonal antibody via a MAPK/lipogenic pathway in human prostate cancer cells J Biol Chem 285 11 2010 7947 7956
-
(2010)
J Biol Chem
, vol.285
, Issue.11
, pp. 7947-7956
-
-
Huang, W.C.1
Zhau, H.E.2
Chung, L.W.3
-
77
-
-
80053923164
-
Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells
-
X. Yang, Z. Guo, F. Sun, W. Li, A. Alfano, and H. Shimelis Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells J Biol Chem 286 41 2011 36152 36160
-
(2011)
J Biol Chem
, vol.286
, Issue.41
, pp. 36152-36160
-
-
Yang, X.1
Guo, Z.2
Sun, F.3
Li, W.4
Alfano, A.5
Shimelis, H.6
-
78
-
-
79959977655
-
Stearoyl CoA desaturase (SCD) facilitates proliferation of prostate cancer cells through enhancement of androgen receptor transactivation
-
S.J. Kim, H. Choi, S.S. Park, C. Chang, and E. Kim Stearoyl CoA desaturase (SCD) facilitates proliferation of prostate cancer cells through enhancement of androgen receptor transactivation Mol Cells 31 4 2011 371 377
-
(2011)
Mol Cells
, vol.31
, Issue.4
, pp. 371-377
-
-
Kim, S.J.1
Choi, H.2
Park, S.S.3
Chang, C.4
Kim, E.5
-
79
-
-
79959909727
-
TOFA (5-tetradecyl-oxy-2-furoic acid) reduces fatty acid synthesis, inhibits expression of AR, neuropilin-1 and Mcl-1 and kills prostate cancer cells independent of p53 status
-
N.V. Guseva, O.W. Rokhlin, R.A. Glover, and M.B. Cohen TOFA (5-tetradecyl-oxy-2-furoic acid) reduces fatty acid synthesis, inhibits expression of AR, neuropilin-1 and Mcl-1 and kills prostate cancer cells independent of p53 status Cancer Biol Ther 12 1 2011 80 85
-
(2011)
Cancer Biol Ther
, vol.12
, Issue.1
, pp. 80-85
-
-
Guseva, N.V.1
Rokhlin, O.W.2
Glover, R.A.3
Cohen, M.B.4
-
80
-
-
10044271037
-
SREBP transcription factors: Master regulators of lipid homeostasis
-
DOI 10.1016/j.biochi.2004.09.018, PII S0300908404001658, Recent Advances in Lipid Metabolism and Related Disorders
-
D. Eberle, B. Hegarty, P. Bossard, P. Ferre, and F. Foufelle SREBP transcription factors: master regulators of lipid homeostasis Biochimie 86 11 2004 839 848 (Pubitemid 39602764)
-
(2004)
Biochimie
, vol.86
, Issue.11
, pp. 839-848
-
-
Eberle, D.1
Hegarty, B.2
Bossard, P.3
Ferre, P.4
Foufelle, F.5
-
81
-
-
1542615071
-
Dysregulation of Sterol Response Element-Binding Proteins and Downstream Effectors in Prostate Cancer during Progression to Androgen Independence
-
DOI 10.1158/0008-5472.CAN-2148-2
-
S.L. Ettinger, R. Sobel, T.G. Whitmore, M. Akbari, D.R. Bradley, and M.E. Gleave Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence Cancer Res 64 6 2004 2212 2221 (Pubitemid 38339475)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 2212-2221
-
-
Ettinger, S.L.1
Sobel, R.2
Whitmore, T.G.3
Akbari, M.4
Bradley, D.R.5
Gleave, M.E.6
Nelson, C.C.7
-
82
-
-
0035195361
-
Human prostate cancer cells lack feedback regulation of low-density lipoprotein receptor and its regulator, SREBP2
-
Y. Chen, and M. Hughes-Fulford Human prostate cancer cells lack feedback regulation of low-density lipoprotein receptor and its regulator, SREBP2 Int J Cancer 91 1 2001 41 45
-
(2001)
Int J Cancer
, vol.91
, Issue.1
, pp. 41-45
-
-
Chen, Y.1
Hughes-Fulford, M.2
-
83
-
-
2342614947
-
Cholesterol and prostate cancer
-
M.R. Freeman, and K.R. Solomon Cholesterol and prostate cancer J Cell Biochem 91 1 2004 54 69
-
(2004)
J Cell Biochem
, vol.91
, Issue.1
, pp. 54-69
-
-
Freeman, M.R.1
Solomon, K.R.2
-
85
-
-
77953764199
-
Statin use and cancer risk: A comprehensive review
-
D.M. Boudreau, O. Yu, and J. Johnson Statin use and cancer risk: a comprehensive review Expert Opin Drug Saf 9 4 2010 603 621
-
(2010)
Expert Opin Drug Saf
, vol.9
, Issue.4
, pp. 603-621
-
-
Boudreau, D.M.1
Yu, O.2
Johnson, J.3
-
86
-
-
23944487796
-
Statins and prostate cancer risk: A case-control study
-
DOI 10.1093/aje/kwi203
-
J. Shannon, S. Tewoderos, M. Garzotto, T.M. Beer, R. Derenick, and A. Palma Statins and prostate cancer risk: a case-control study Am J Epidemiol 162 4 2005 318 325 (Pubitemid 41389713)
-
(2005)
American Journal of Epidemiology
, vol.162
, Issue.4
, pp. 318-325
-
-
Shannon, J.1
Tewoderos, S.2
Garzotto, M.3
Beer, T.M.4
Derenick, R.5
Palma, A.6
Farris, P.E.7
-
87
-
-
42949170875
-
Do the cholesterol-lowering properties of statins affect cancer risk?
-
DOI 10.1016/j.tem.2007.12.004, PII S104327600800043X
-
K.R. Solomon, and M.R. Freeman Do the cholesterol-lowering properties of statins affect cancer risk? Trends Endocrinol Metab 19 4 2008 113 121 (Pubitemid 351608305)
-
(2008)
Trends in Endocrinology and Metabolism
, vol.19
, Issue.4
, pp. 113-121
-
-
Solomon, K.R.1
Freeman, M.R.2
-
88
-
-
84860710342
-
Statins and prostate cancer: Role of cholesterol inhibition vs. prevention of small GTP-binding proteins
-
M. Roy, H.J. Kung, and P.M. Ghosh Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins Am J Cancer Res 1 4 2011 542 561
-
(2011)
Am J Cancer Res
, vol.1
, Issue.4
, pp. 542-561
-
-
Roy, M.1
Kung, H.J.2
Ghosh, P.M.3
-
89
-
-
77955909525
-
Prostate specific antigen reduction following statin therapy: Mechanism of action and review of the literature
-
D.J. Mener Prostate specific antigen reduction following statin therapy: mechanism of action and review of the literature IUBMB Life 62 8 2010 584 590
-
(2010)
IUBMB Life
, vol.62
, Issue.8
, pp. 584-590
-
-
Mener, D.J.1
-
91
-
-
79959786680
-
Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response
-
V.K. Grover, J.G. Valadez, A.B. Bowman, and M.K. Cooper Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response PLoS ONE 6 7 2011 e21353
-
(2011)
PLoS ONE
, vol.6
, Issue.7
, pp. 21353
-
-
Grover, V.K.1
Valadez, J.G.2
Bowman, A.B.3
Cooper, M.K.4
-
92
-
-
35648995949
-
Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, notch, and bone morphogenic proteins
-
DOI 10.1002/jcb.21509
-
J.M. Bailey, P.K. Singh, and M.A. Hollingsworth Cancer metastasis facilitated by developmental pathways: sonic hedgehog, Notch, and bone morphogenic proteins J Cell Biochem 102 4 2007 829 839 (Pubitemid 350036923)
-
(2007)
Journal of Cellular Biochemistry
, vol.102
, Issue.4
, pp. 829-839
-
-
Bailey, J.M.1
Singh, P.K.2
Hollingsworth, M.A.3
-
93
-
-
79955073961
-
Lipid rafts: Signaling and sorting platforms of cells and their roles in cancer
-
S. Staubach, and F.G. Hanisch Lipid rafts: signaling and sorting platforms of cells and their roles in cancer Expert Rev Proteom 8 2 2011 263 277
-
(2011)
Expert Rev Proteom
, vol.8
, Issue.2
, pp. 263-277
-
-
Staubach, S.1
Hanisch, F.G.2
-
94
-
-
21644452110
-
Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: Genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice
-
DOI 10.1074/jbc.M501186200
-
T.M. Williams, G.S. Hassan, J. Li, A.W. Cohen, F. Medina, and P.G. Frank Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice J Biol Chem 280 26 2005 25134 25145 (Pubitemid 40934606)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 25134-25145
-
-
Williams, T.M.1
Hassan, G.S.2
Li, J.3
Cohen, A.W.4
Medina, F.5
Frank, P.G.6
Pestell, R.G.7
Vizio, D.D.8
Loda, M.9
Lisanti, M.P.10
-
95
-
-
79952984219
-
Statins and prostate cancer: Molecular and clinical aspects
-
G. Papadopoulos, D. Delakas, L. Nakopoulou, and T. Kassimatis Statins and prostate cancer: molecular and clinical aspects Eur J Cancer 47 6 2011 819 830
-
(2011)
Eur J Cancer
, vol.47
, Issue.6
, pp. 819-830
-
-
Papadopoulos, G.1
Delakas, D.2
Nakopoulou, L.3
Kassimatis, T.4
-
96
-
-
78649888652
-
Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer patients
-
S. Crnalic, E. Hornberg, P. Wikstrom, U.H. Lerner, A. Tieva, and O. Svensson Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer patients Endocr Relat Cancer 17 4 2010 885 895
-
(2010)
Endocr Relat Cancer
, vol.17
, Issue.4
, pp. 885-895
-
-
Crnalic, S.1
Hornberg, E.2
Wikstrom, P.3
Lerner, U.H.4
Tieva, A.5
Svensson, O.6
-
97
-
-
34250331066
-
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer
-
DOI 10.1158/0008-5472.CAN-06-3332
-
E.A. Mostaghel, S.T. Page, D.W. Lin, L. Fazli, I.M. Coleman, and L.D. True Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer Cancer Res 67 10 2007 5033 5041 (Pubitemid 46910214)
-
(2007)
Cancer Research
, vol.67
, Issue.10
, pp. 5033-5041
-
-
Mostaghel, E.A.1
Page, S.T.2
Lin, D.W.3
Fazli, L.4
Coleman, I.M.5
True, L.D.6
Knudsen, B.7
Hess, D.L.8
Nelson, C.C.9
Matsumoto, A.M.10
Bremner, W.J.11
Gleave, M.E.12
Nelson, P.S.13
-
98
-
-
80054021222
-
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors
-
C. Cai, S. Chen, P. Ng, G.J. Bubley, P.S. Nelson, and E.A. Mostaghel Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors Cancer Res 71 20 2011 6503 6513
-
(2011)
Cancer Res
, vol.71
, Issue.20
, pp. 6503-6513
-
-
Cai, C.1
Chen, S.2
Ng, P.3
Bubley, G.J.4
Nelson, P.S.5
Mostaghel, E.A.6
-
99
-
-
80053940699
-
Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy
-
C. Cai, and S.P. Balk Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy Endocr Relat Cancer 18 5 2011 R175 R182
-
(2011)
Endocr Relat Cancer
, vol.18
, Issue.5
-
-
Cai, C.1
Balk, S.P.2
-
100
-
-
78649944454
-
Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol
-
E. Thysell, I. Surowiec, E. Hornberg, S. Crnalic, A. Widmark, and A.I. Johansson Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol PLoS ONE 5 12 2010 e14175
-
(2010)
PLoS ONE
, vol.5
, Issue.12
, pp. 14175
-
-
Thysell, E.1
Surowiec, I.2
Hornberg, E.3
Crnalic, S.4
Widmark, A.5
Johansson, A.I.6
-
101
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
-
R.B. Montgomery, E.A. Mostaghel, R. Vessella, D.L. Hess, T.F. Kalhorn, and C.S. Higano Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth Cancer Res 68 11 2008 4447 4454
-
(2008)
Cancer Res
, vol.68
, Issue.11
, pp. 4447-4454
-
-
Montgomery, R.B.1
Mostaghel, E.A.2
Vessella, R.3
Hess, D.L.4
Kalhorn, T.F.5
Higano, C.S.6
-
102
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
J.A. Locke, E.S. Guns, A.A. Lubik, H.H. Adomat, S.C. Hendy, and C.A. Wood Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer Cancer Res 68 15 2008 6407 6415
-
(2008)
Cancer Res
, vol.68
, Issue.15
, pp. 6407-6415
-
-
Locke, J.A.1
Guns, E.S.2
Lubik, A.A.3
Adomat, H.H.4
Hendy, S.C.5
Wood, C.A.6
-
103
-
-
84855921875
-
Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors
-
E.A. Mostaghel, K.R. Solomon, K. Pelton, M.R. Freeman, and R.B. Montgomery Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors PLoS ONE 7 1 2012 e30062
-
(2012)
PLoS ONE
, vol.7
, Issue.1
, pp. 30062
-
-
Mostaghel, E.A.1
Solomon, K.R.2
Pelton, K.3
Freeman, M.R.4
Montgomery, R.B.5
-
104
-
-
0041337028
-
Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells
-
DOI 10.1002/ijc.11317
-
K. Brusselmans, E. De Schrijver, W. Heyns, G. Verhoeven, and J.V. Swinnen Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells Int J Cancer 106 6 2003 856 862 (Pubitemid 37071663)
-
(2003)
International Journal of Cancer
, vol.106
, Issue.6
, pp. 856-862
-
-
Brusselmans, K.1
De Schrijver, E.2
Heyns, W.3
Verhoeven, G.4
Swinnen, J.V.5
-
105
-
-
37249017959
-
Selective inhibition of fatty acid synthase for lung cancer treatment
-
DOI 10.1158/1078-0432.CCR-07-1186
-
H. Orita, J. Coulter, C. Lemmon, E. Tully, A. Vadlamudi, and S.M. Medghalchi Selective inhibition of fatty acid synthase for lung cancer treatment Clin Cancer Res 13 23 2007 7139 7145 (Pubitemid 350276900)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.23
, pp. 7139-7145
-
-
Orita, H.1
Coulter, J.2
Lemmon, C.3
Tully, E.4
Vadlamudi, A.5
Medghalchi, S.M.6
Kuhajda, F.P.7
Gabrielson, E.8
-
106
-
-
13944267828
-
Application of a flexible synthesis of (5R)-thiolactomycin to develop new inhibitors of type I fatty acid synthase
-
DOI 10.1021/jm049389h
-
J.M. McFadden, S.M. Medghalchi, J.N. Thupari, M.L. Pinn, A. Vadlamudi, and K.I. Miller Application of a flexible synthesis of (5R)-thiolactomycin to develop new inhibitors of type I fatty acid synthase J Med Chem 48 4 2005 946 961 (Pubitemid 40270441)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.4
, pp. 946-961
-
-
McFadden, J.M.1
Medghalchi, S.M.2
Thupari, J.N.3
Pinn, M.L.4
Vadlamudi, A.5
Miller, K.I.6
Kuhajda, F.P.7
Townsend, C.A.8
-
107
-
-
0034733730
-
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
-
DOI 10.1126/science.288.5475.2379
-
T.M. Loftus, D.E. Jaworsky, G.L. Frehywot, C.A. Townsend, G.V. Ronnett, and M.D. Lane Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors Science 288 5475 2000 2379 2381 (Pubitemid 30448165)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2379-2381
-
-
Loftus, T.M.1
Jaworsky, D.E.2
Frehywot, C.L.3
Townsend, C.A.4
Ronnett, G.V.5
Daniel Lane, M.6
Kuhajda, F.P.7
-
108
-
-
0034724397
-
Synthesis and antitumor activity of an inhibitor of fatty acid synthase
-
DOI 10.1073/pnas.050582897
-
F.P. Kuhajda, E.S. Pizer, J.N. Li, N.S. Mani, G.L. Frehywot, and C.A. Townsend Synthesis and antitumor activity of an inhibitor of fatty acid synthase Proc Natl Acad Sci U S A 97 7 2000 3450 3454 (Pubitemid 30183323)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3450-3454
-
-
Kuhajda, F.P.1
Pizer, E.S.2
Li, J.N.3
Mani, N.S.4
Frehywot, G.L.5
Townsend, C.A.6
-
109
-
-
40749124510
-
Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the β-ketoacyl reductase reaction
-
DOI 10.1111/j.1742-4658.2008.06314.x
-
M.J. Vazquez, W. Leavens, R. Liu, B. Rodriguez, M. Read, and S. Richards Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the beta-ketoacyl reductase reaction FEBS J 275 7 2008 1556 1567 (Pubitemid 351388801)
-
(2008)
FEBS Journal
, vol.275
, Issue.7
, pp. 1556-1567
-
-
Vazquez, M.J.1
Leavens, W.2
Liu, R.3
Rodriguez, B.4
Read, M.5
Richards, S.6
Winegar, D.7
Dominguez, J.M.8
-
110
-
-
51149098989
-
The crystal structure of a mammalian fatty acid synthase
-
T. Maier, M. Leibundgut, and N. Ban The crystal structure of a mammalian fatty acid synthase Science 321 5894 2008 1315 1322
-
(2008)
Science
, vol.321
, Issue.5894
, pp. 1315-1322
-
-
Maier, T.1
Leibundgut, M.2
Ban, N.3
-
111
-
-
2442631468
-
C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase
-
DOI 10.1074/jbc.M402165200
-
E.K. Kim, I. Miller, S. Aja, L.E. Landree, M. Pinn, and J. McFadden C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase J Biol Chem 279 19 2004 19970 19976 (Pubitemid 38623439)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 19970-19976
-
-
Kim, E.-K.1
Miller, I.2
Aja, S.3
Landree, L.E.4
Pinn, M.5
McFadden, J.6
Kuhajda, F.P.7
Moran, T.H.8
Ronnett, G.V.9
-
112
-
-
9144219529
-
C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism
-
DOI 10.1074/jbc.M310991200
-
L.E. Landree, A.L. Hanlon, D.W. Strong, G. Rumbaugh, I.M. Miller, and J.N. Thupari C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism J Biol Chem 279 5 2004 3817 3827 (Pubitemid 38140627)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.5
, pp. 3817-3827
-
-
Landree, L.E.1
Hanlon, A.L.2
Strong, D.W.3
Rumbaugh, G.4
Miller, I.M.5
Thupari, J.N.6
Connolly, E.C.7
Huganir, R.L.8
Richardson, C.9
Witters, L.A.10
Kuhajda, F.P.11
Ronnett, G.V.12
-
113
-
-
80052767622
-
The link between the metabolic syndrome and cancer
-
S. Braun, K. Bitton-Worms, and D. LeRoith The link between the metabolic syndrome and cancer Int J Biol Sci 7 7 2011 1003 1015
-
(2011)
Int J Biol Sci
, vol.7
, Issue.7
, pp. 1003-1015
-
-
Braun, S.1
Bitton-Worms, K.2
Leroith, D.3
-
114
-
-
85027950107
-
Metabolic diseases and cancer risk
-
M.H. Faulds, and K. Dahlman-Wright Metabolic diseases and cancer risk Curr Opin Oncol 24 1 2012 58 61
-
(2012)
Curr Opin Oncol
, vol.24
, Issue.1
, pp. 58-61
-
-
Faulds, M.H.1
Dahlman-Wright, K.2
-
115
-
-
77950509620
-
A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases
-
H.A. Hirsch, D. Iliopoulos, A. Joshi, Y. Zhang, S.A. Jaeger, and M. Bulyk A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases Cancer Cell 17 4 2010 348 361
-
(2010)
Cancer Cell
, vol.17
, Issue.4
, pp. 348-361
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Joshi, A.3
Zhang, Y.4
Jaeger, S.A.5
Bulyk, M.6
-
116
-
-
67749144226
-
Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer
-
S. Jiralerspong, S.L. Palla, S.H. Giordano, F. Meric-Bernstam, C. Liedtke, and C.M. Barnett Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer J Clin Oncol 27 20 2009 3297 3302
-
(2009)
J Clin Oncol
, vol.27
, Issue.20
, pp. 3297-3302
-
-
Jiralerspong, S.1
Palla, S.L.2
Giordano, S.H.3
Meric-Bernstam, F.4
Liedtke, C.5
Barnett, C.M.6
-
117
-
-
3843061592
-
AMP kinase and malonyl-CoA: Targets for therapy of the metabolic syndrome
-
N. Ruderman, and M. Prentki AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome Nat Rev Drug Discov 3 4 2004 340 351 (Pubitemid 38499761)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.4
, pp. 340-351
-
-
Ruderman, N.1
Prentki, M.2
-
118
-
-
12844281251
-
AMPK, the metabolic syndrome and cancer
-
DOI 10.1016/j.tips.2004.12.011, PII S0165614704003402
-
Z. Luo, A.K. Saha, X. Xiang, and N.B. Ruderman AMPK, the metabolic syndrome and cancer Trends Pharmacol Sci 26 2 2005 69 76 (Pubitemid 40170168)
-
(2005)
Trends in Pharmacological Sciences
, vol.26
, Issue.2
, pp. 69-76
-
-
Luo, Z.1
Saha, A.K.2
Xiang, X.3
Ruderman, N.B.4
-
119
-
-
0037326307
-
Physiological role of AMP-activated protein kinase (AMPK): Insights from knockout mouse models
-
B. Viollet, F. Andreelli, S.B. Jorgensen, C. Perrin, D. Flamez, and J. Mu Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models Biochem Soc Trans 31 Pt 1 2003 216 219 (Pubitemid 36241431)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.1
, pp. 216-219
-
-
Viollet, B.1
Andreelli, F.2
Jorgensen, S.B.3
Perrin, C.4
Flamez, D.5
Mu, J.6
Wojtaszewski, J.F.P.7
Schuit, F.C.8
Birnbaum, M.9
Richter, E.10
Burcelin, R.11
Vaulont, S.12
-
120
-
-
77954234363
-
New strategies in prostate cancer: Targeting lipogenic pathways and the energy sensor AMPK
-
G. Zadra, C. Priolo, A. Patnaik, and M. Loda New strategies in prostate cancer: targeting lipogenic pathways and the energy sensor AMPK Clin Cancer Res 16 13 2010 3322 3328
-
(2010)
Clin Cancer Res
, vol.16
, Issue.13
, pp. 3322-3328
-
-
Zadra, G.1
Priolo, C.2
Patnaik, A.3
Loda, M.4
-
121
-
-
78649998496
-
Metabolic alterations and targeted therapies in prostate cancer
-
R. Flavin, G. Zadra, and M. Loda Metabolic alterations and targeted therapies in prostate cancer J Pathol 223 2011 283 294
-
(2011)
J Pathol
, Issue.223
, pp. 283-294
-
-
Flavin, R.1
Zadra, G.2
Loda, M.3
-
122
-
-
0142106795
-
Increased Fatty Acid Synthase Expression and Activity During Progression of Prostate Cancer in the TRAMP Model
-
DOI 10.1002/pros.10297
-
B.R. Pflug, S.M. Pecher, A.W. Brink, J.B. Nelson, and B.A. Foster Increased fatty acid synthase expression and activity during progression of prostate cancer in the TRAMP model Prostate 57 3 2003 245 254 (Pubitemid 37267807)
-
(2003)
Prostate
, vol.57
, Issue.3
, pp. 245-254
-
-
Pflug, B.R.1
Pecher, S.M.2
Brink, A.W.3
Nelson, J.B.4
Foster, B.A.5
-
123
-
-
79961001505
-
Is there a role for fatty acid synthase in the diagnosis of prostatic adenocarcinoma?: A comparison with AMACR
-
X. Wu, M. Zayzafoon, X. Zhang, and O. Hameed Is there a role for fatty acid synthase in the diagnosis of prostatic adenocarcinoma?: A comparison with AMACR Am J Clin Pathol 136 2 2011 239 246
-
(2011)
Am J Clin Pathol
, vol.136
, Issue.2
, pp. 239-246
-
-
Wu, X.1
Zayzafoon, M.2
Zhang, X.3
Hameed, O.4
-
124
-
-
78651095516
-
18F]fluoroglutamic acid (BAY 85-8050), a new amino acid radiotracer for PET imaging of tumors: Synthesis and in vitro characterization
-
18F]fluoroglutamic acid (BAY 85-8050), a new amino acid radiotracer for PET imaging of tumors: synthesis and in vitro characterization J Med Chem 54 1 2011 406 410
-
(2011)
J Med Chem
, vol.54
, Issue.1
, pp. 406-410
-
-
Krasikova, R.N.1
Kuznetsova, O.F.2
Fedorova, O.S.3
Belokon, Y.N.4
Maleev, V.I.5
Mu, L.6
-
125
-
-
0036008186
-
11C-acetate PET imaging of prostate cancer
-
11C-acetate PET imaging of prostate cancer J Nucl Med 43 2 2002 181 186 (Pubitemid 34151040)
-
(2002)
Journal of Nuclear Medicine
, vol.43
, Issue.2
, pp. 181-186
-
-
Oyama, N.1
Akino, H.2
Kanamaru, H.3
Suzuki, Y.4
Muramoto, S.5
Yonekura, Y.6
Sadato, N.7
Yamamoto, K.8
Okada, K.9
-
126
-
-
12444324170
-
18F-FDG in prostate cancer patients
-
18F-FDG in prostate cancer patients Eur J Nucl Med Mol Imaging 30 4 2003 607 611 (Pubitemid 36559841)
-
(2003)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.30
, Issue.4
, pp. 607-611
-
-
Fricke, E.1
Machtens, S.2
Hofmann, M.3
Van Den Hoff, J.4
Bergh, S.5
Brunkhorst, T.6
Meyer, G.J.7
Karstens, J.H.8
Knapp, W.H.9
Boerner, A.R.10
-
127
-
-
38949208937
-
11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer
-
DOI 10.2967/jnumed.107.046672
-
11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer J Nucl Med 49 2 2008 327 334 (Pubitemid 351225673)
-
(2008)
Journal of Nuclear Medicine
, vol.49
, Issue.2
, pp. 327-334
-
-
Vavere, A.L.1
Kridel, S.J.2
Wheeler, F.B.3
Lewis, J.S.4
-
129
-
-
33846570585
-
Body mass index, weight change, and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort
-
DOI 10.1158/1055-9965.EPI-06-0754
-
C. Rodriguez, S.J. Freedland, A. Deka, E.J. Jacobs, M.L. McCullough, and A.V. Patel Body mass index, weight change, and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort Cancer Epidemiol Biomarkers Prev 16 1 2007 63 69 (Pubitemid 46174265)
-
(2007)
Cancer Epidemiology Biomarkers and Prevention
, vol.16
, Issue.1
, pp. 63-69
-
-
Rodriguez, C.1
Freedland, S.J.2
Deka, A.3
Jacobs, E.J.4
McCullough, M.L.5
Patel, A.V.6
Thun, M.J.7
Calle, E.E.8
-
130
-
-
34547736129
-
Risk factors for prostate cancer incidence and progression in the health professionals follow-up study
-
DOI 10.1002/ijc.22788
-
E. Giovannucci, Y. Liu, E.A. Platz, M.J. Stampfer, and W.C. Willett Risk factors for prostate cancer incidence and progression in the health professionals follow-up study Int J Cancer 121 7 2007 1571 1578 (Pubitemid 47328718)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.7
, pp. 1571-1578
-
-
Giovannucci, E.1
Liu, Y.2
Platz, E.A.3
Stampfer, M.J.4
Willett, W.C.5
-
131
-
-
26444519930
-
Obesity and prostate cancer: A growing problem
-
DOI 10.1158/1078-0432.CCR-05-1305
-
S.J. Freedland Obesity and prostate cancer: a growing problem Clin Cancer Res 11 19 Pt 1 2005 6763 6766 (Pubitemid 41428728)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.19 PART 1
, pp. 6763-6766
-
-
Freedland, S.J.1
-
132
-
-
39449083288
-
Candidate genes involved in enhanced growth of human prostate cancer under high fat feeding identified by microarray analysis
-
DOI 10.1002/pros.20681
-
S. Narita, N. Tsuchiya, M. Saito, T. Inoue, T. Kumazawa, and T. Yuasa Candidate genes involved in enhanced growth of human prostate cancer under high fat feeding identified by microarray analysis Prostate 68 3 2008 321 335 (Pubitemid 351273061)
-
(2008)
Prostate
, vol.68
, Issue.3
, pp. 321-335
-
-
Narita, S.1
Tsuchiya, N.2
Saito, M.3
Inoue, T.4
Kumazawa, T.5
Yuasa, T.6
Nakamura, A.7
Habuchi, T.8
-
133
-
-
0033577233
-
Energy intake and prostate tumor growth, angiogenesis, and vascular endothelial growth factor expression
-
P. Mukherjee, A.V. Sotnikov, H.J. Mangian, J.R. Zhou, W.J. Visek, and S.K. Clinton Energy intake and prostate tumor growth, angiogenesis, and vascular endothelial growth factor expression J Natl Cancer Inst 91 6 1999 512 523 (Pubitemid 29157059)
-
(1999)
Journal of the National Cancer Institute
, vol.91
, Issue.6
, pp. 512-523
-
-
Mukherjee, P.1
Sotnikov, A.V.2
Mangian, H.J.3
Zhou, J.-R.4
Visek, W.J.5
Clinton, S.K.6
-
134
-
-
71449095792
-
Growth inhibitory effect of low fat diet on prostate cancer cells: Results of a prospective, randomized dietary intervention trial in men with prostate cancer
-
W.J. Aronson, R.J. Barnard, S.J. Freedland, S. Henning, D. Elashoff, and P.M. Jardack Growth inhibitory effect of low fat diet on prostate cancer cells: results of a prospective, randomized dietary intervention trial in men with prostate cancer J Urol 183 1 2010 345 350
-
(2010)
J Urol
, vol.183
, Issue.1
, pp. 345-350
-
-
Aronson, W.J.1
Barnard, R.J.2
Freedland, S.J.3
Henning, S.4
Elashoff, D.5
Jardack, P.M.6
-
135
-
-
78751561494
-
Major dietary factors and prostate cancer risk: A prospective multicenter case-control study
-
S. Salem, M. Salahi, M. Mohseni, H. Ahmadi, A. Mehrsai, and Y. Jahani Major dietary factors and prostate cancer risk: a prospective multicenter case-control study Nutr Cancer 63 1 2011 21 27
-
(2011)
Nutr Cancer
, vol.63
, Issue.1
, pp. 21-27
-
-
Salem, S.1
Salahi, M.2
Mohseni, M.3
Ahmadi, H.4
Mehrsai, A.5
Jahani, Y.6
-
136
-
-
78650189267
-
A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer
-
G. Llaverias, C. Danilo, Y. Wang, A.K. Witkiewicz, K. Daumer, and M.P. Lisanti A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer Am J Pathol 177 6 2010 3180 3191
-
(2010)
Am J Pathol
, vol.177
, Issue.6
, pp. 3180-3191
-
-
Llaverias, G.1
Danilo, C.2
Wang, Y.3
Witkiewicz, A.K.4
Daumer, K.5
Lisanti, M.P.6
-
137
-
-
42349094502
-
Effect of low-fat diet on development of prostate cancer and Akt phosphorylation in the Hi-Myc transgenic mouse model
-
DOI 10.1158/0008-5472.CAN-07-5616
-
N. Kobayashi, R.J. Barnard, J. Said, J. Hong-Gonzalez, D.M. Corman, and M. Ku Effect of low-fat diet on development of prostate cancer and Akt phosphorylation in the Hi-Myc transgenic mouse model Cancer Res 68 8 2008 3066 3073 (Pubitemid 351556309)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 3066-3073
-
-
Kobayashi, N.1
Barnard, R.J.2
Said, J.3
Hong-Gonzalez, J.4
Corman, D.M.5
Ku, M.6
Ngan, B.D.7
Gui, D.8
Elashoff, D.9
Cohen, P.10
Aronson, W.J.11
-
138
-
-
77952565856
-
Dietary fat and early-onset prostate cancer risk
-
A. Lophatananon, J. Archer, D. Easton, R. Pocock, D. Dearnaley, and M. Guy Dietary fat and early-onset prostate cancer risk Br J Nutr 103 9 2010 1375 1380
-
(2010)
Br J Nutr
, vol.103
, Issue.9
, pp. 1375-1380
-
-
Lophatananon, A.1
Archer, J.2
Easton, D.3
Pocock, R.4
Dearnaley, D.5
Guy, M.6
-
139
-
-
37449034484
-
Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis
-
S.J. Freedland, J. Mavropoulos, A. Wang, M. Darshan, W. Demark-Wahnefried, and W.J. Aronson Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis Prostate 68 1 2008 11 19
-
(2008)
Prostate
, vol.68
, Issue.1
, pp. 11-19
-
-
Freedland, S.J.1
Mavropoulos, J.2
Wang, A.3
Darshan, M.4
Demark-Wahnefried, W.5
Aronson, W.J.6
-
140
-
-
77949338911
-
Effect of isocaloric low fat diet on prostate cancer xenograft progression in a hormone deprivation model
-
J.C. Lloyd, J.A. Antonelli, T.E. Phillips, E.M. Masko, J.A. Thomas, and S.H. Poulton Effect of isocaloric low fat diet on prostate cancer xenograft progression in a hormone deprivation model J Urol 183 4 2010 1619 1624
-
(2010)
J Urol
, vol.183
, Issue.4
, pp. 1619-1624
-
-
Lloyd, J.C.1
Antonelli, J.A.2
Phillips, T.E.3
Masko, E.M.4
Thomas, J.A.5
Poulton, S.H.6
-
141
-
-
4444263339
-
Problems with the assessment of dietary fat in prostate cancer studies
-
DOI 10.1093/aje/kwh243
-
L.K. Dennis, L.G. Snetselaar, B.J. Smith, R.E. Stewart, and M.E. Robbins Problems with the assessment of dietary fat in prostate cancer studies Am J Epidemiol 160 5 2004 436 444 (Pubitemid 39166976)
-
(2004)
American Journal of Epidemiology
, vol.160
, Issue.5
, pp. 436-444
-
-
Dennis, L.K.1
Snetselaar, L.G.2
Smith, B.J.3
Stewart, R.E.4
Robbins, M.E.C.5
-
143
-
-
42549115339
-
Saturated fat intake predicts biochemical failure after prostatectomy
-
DOI 10.1002/ijc.23414
-
S.S. Strom, Y. Yamamura, M.R. Forman, C.A. Pettaway, S.L. Barrera, and J. DiGiovanni Saturated fat intake predicts biochemical failure after prostatectomy Int J Cancer 122 11 2008 2581 2585 (Pubitemid 351590493)
-
(2008)
International Journal of Cancer
, vol.122
, Issue.11
, pp. 2581-2585
-
-
Strom, S.S.1
Yamamura, Y.2
Forman, M.R.3
Pettaway, C.A.4
Barrera, S.L.5
DiGiovanni, J.6
-
144
-
-
58849113459
-
Circulating fatty acids and prostate cancer risk in a nested case-control study: The Multiethnic Cohort
-
S.Y. Park, L.R. Wilkens, S.M. Henning, L. Le Marchand, K. Gao, and M.T. Goodman Circulating fatty acids and prostate cancer risk in a nested case-control study: the Multiethnic Cohort Cancer Causes Control 20 2 2009 211 223
-
(2009)
Cancer Causes Control
, vol.20
, Issue.2
, pp. 211-223
-
-
Park, S.Y.1
Wilkens, L.R.2
Henning, S.M.3
Le Marchand, L.4
Gao, K.5
Goodman, M.T.6
-
145
-
-
0028952799
-
Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada
-
A.S. Whittemore, L.N. Kolonel, A.H. Wu, E.M. John, R.P. Gallagher, and G.R. Howe Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada J Natl Cancer Inst 87 9 1995 652 661
-
(1995)
J Natl Cancer Inst
, vol.87
, Issue.9
, pp. 652-661
-
-
Whittemore, A.S.1
Kolonel, L.N.2
Wu, A.H.3
John, E.M.4
Gallagher, R.P.5
Howe, G.R.6
-
146
-
-
82955233448
-
Associations of whole-blood fatty acids and dietary intakes with prostate cancer in Jamaica
-
M.D. Jackson, S.P. Walker, C.M. Simpson-Smith, C.M. Lindsay, G. Smith, and N. McFarlane-Anderson Associations of whole-blood fatty acids and dietary intakes with prostate cancer in Jamaica Cancer Causes Control 23 1 2012 23 33
-
(2012)
Cancer Causes Control
, vol.23
, Issue.1
, pp. 23-33
-
-
Jackson, M.D.1
Walker, S.P.2
Simpson-Smith, C.M.3
Lindsay, C.M.4
Smith, G.5
McFarlane-Anderson, N.6
-
147
-
-
43549106350
-
Dietary fat intake and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition
-
F.L. Crowe, T.J. Key, P.N. Appleby, R.C. Travis, K. Overvad, and M.U. Jakobsen Dietary fat intake and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition Am J Clin Nutr 87 5 2008 1405 1413 (Pubitemid 351679784)
-
(2008)
American Journal of Clinical Nutrition
, vol.87
, Issue.5
, pp. 1405-1413
-
-
Crowe, F.L.1
Key, T.J.2
Appleby, P.N.3
Travis, R.C.4
Overvad, K.5
Jakobsen, M.U.6
Johnsen, N.F.7
Tjonneland, A.8
Linseisen, J.9
Rohrmann, S.10
Boeing, H.11
Pischon, T.12
Trichopoulou, A.13
Lagiou, P.14
Trichopoulos, D.15
Sacerdote, C.16
Palli, D.17
Tumino, R.18
Krogh, V.19
Bueno-de-Mesquita, H.B.20
Kiemeney, L.A.21
Chirlaque, M.-D.22
Ardanaz, E.23
Sanchez, M.-J.24
Larranaga, N.25
Gonzalez, C.A.26
Quiros, J.R.27
Manjer, J.28
Wirfalt, E.29
Stattin, P.30
Hallmans, G.31
Khaw, K.-T.32
Bingham, S.33
Ferrari, P.34
Slimani, N.35
Jenab, M.36
Riboli, E.37
more..
-
148
-
-
42149156601
-
Dairy product, saturated fatty acid, and calcium intake and prostate cancer in a prospective cohort of Japanese men
-
DOI 10.1158/1055-9965.EPI-07-2681
-
N. Kurahashi, M. Inoue, M. Iwasaki, S. Sasazuki, and A.S. Tsugane Dairy product, saturated fatty acid, and calcium intake and prostate cancer in a prospective cohort of Japanese men Cancer Epidemiol Biomarkers Prev 17 4 2008 930 937 (Pubitemid 351536425)
-
(2008)
Cancer Epidemiology Biomarkers and Prevention
, vol.17
, Issue.4
, pp. 930-937
-
-
Kurahashi, N.1
Inoue, M.2
Iwasaki, M.3
Sasazuki, S.4
Tsugane, S.5
-
149
-
-
34447339099
-
Effects of coconut oil on testosterone-induced prostatic hyperplasia in Sprague-Dawley rats
-
DOI 10.1211/jpp.59.7.0012
-
M. de Lourdes Arruzazabala, V. Molina, R. Mas, D. Carbajal, D. Marrero, and V. Gonzalez Effects of coconut oil on testosterone-induced prostatic hyperplasia in Sprague-Dawley rats J Pharm Pharmacol 59 7 2007 995 999 (Pubitemid 47051081)
-
(2007)
Journal of Pharmacy and Pharmacology
, vol.59
, Issue.7
, pp. 995-999
-
-
Arruzazabala, M.D.L.1
Molina, V.2
Mas, R.3
Carbajal, D.4
Marrero, D.5
Gonzalez, V.6
Rodriguez, E.7
-
150
-
-
61949483298
-
Dietary fatty acid quality affects AR and PPARgamma levels and prostate growth
-
E.L. Escobar, M.C. Gomes-Marcondes, and H.F. Carvalho Dietary fatty acid quality affects AR and PPARgamma levels and prostate growth Prostate 69 5 2009 548 558
-
(2009)
Prostate
, vol.69
, Issue.5
, pp. 548-558
-
-
Escobar, E.L.1
Gomes-Marcondes, M.C.2
Carvalho, H.F.3
-
151
-
-
70350244514
-
Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism
-
K. Tamura, A. Makino, F. Hullin-Matsuda, T. Kobayashi, M. Furihata, and S. Chung Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism Cancer Res 69 20 2009 8133 8140
-
(2009)
Cancer Res
, vol.69
, Issue.20
, pp. 8133-8140
-
-
Tamura, K.1
Makino, A.2
Hullin-Matsuda, F.3
Kobayashi, T.4
Furihata, M.5
Chung, S.6
-
152
-
-
80054087224
-
Biochemical characterization of the very long-chain fatty acid elongase ELOVL7
-
T. Naganuma, Y. Sato, T. Sassa, Y. Ohno, and A. Kihara Biochemical characterization of the very long-chain fatty acid elongase ELOVL7 FEBS Lett 585 20 2011 3337 3341
-
(2011)
FEBS Lett
, vol.585
, Issue.20
, pp. 3337-3341
-
-
Naganuma, T.1
Sato, Y.2
Sassa, T.3
Ohno, Y.4
Kihara, A.5
-
153
-
-
73549107655
-
Novel biomarkers for prostate cancer including noncoding transcripts
-
T.L. Romanuik, T. Ueda, N. Le, S. Haile, T.M. Yong, and T. Thomson Novel biomarkers for prostate cancer including noncoding transcripts Am J Pathol 175 6 2009 2264 2276
-
(2009)
Am J Pathol
, vol.175
, Issue.6
, pp. 2264-2276
-
-
Romanuik, T.L.1
Ueda, T.2
Le, N.3
Haile, S.4
Yong, T.M.5
Thomson, T.6
-
154
-
-
34548860424
-
Brain fatty acid synthase activates PPAR? to maintain energy homeostasis
-
DOI 10.1172/JCI31183
-
M.V. Chakravarthy, Y. Zhu, M. Lopez, L. Yin, D.F. Wozniak, and T. Coleman Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis J Clin Invest 117 9 2007 2539 2552 (Pubitemid 47494355)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.9
, pp. 2539-2552
-
-
Chakravarthy, M.V.1
Zhu, Y.2
Lopez, M.3
Yin, L.4
Wozniak, D.F.5
Coleman, T.6
Hu, Z.7
Wolfgang, M.8
Vidal-Puig, A.9
Lane, M.D.10
Semenkovich, C.F.11
-
155
-
-
22544480378
-
"New" hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis
-
DOI 10.1016/j.cmet.2005.04.002, PII S1550413105001105
-
M.V. Chakravarthy, Z. Pan, Y. Zhu, K. Tordjman, J.G. Schneider, and T. Coleman New hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis Cell Metab 1 5 2005 309 322 (Pubitemid 43977168)
-
(2005)
Cell Metabolism
, vol.1
, Issue.5
, pp. 309-322
-
-
Chakravarthy, M.V.1
Pan, Z.2
Zhu, Y.3
Tordjman, K.4
Schneider, J.G.5
Coleman, T.6
Turk, J.7
Semenkovich, C.F.8
-
156
-
-
0033796213
-
Cancer and Mediterranean dietary traditions
-
A. Trichopoulou, P. Lagiou, H. Kuper, and D. Trichopoulos Cancer and Mediterranean dietary traditions Cancer Epidemiol Biomarkers Prev 9 9 2000 869 873
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, Issue.9
, pp. 869-873
-
-
Trichopoulou, A.1
Lagiou, P.2
Kuper, H.3
Trichopoulos, D.4
-
157
-
-
77950952757
-
Olive oil and health: Summary of the II international conference on olive oil and health consensus report, Jaen and Cordoba (Spain) 2008
-
J. Lopez-Miranda, F. Perez-Jimenez, E. Ros, R. De Caterina, L. Badimon, and M.I. Covas Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaen and Cordoba (Spain) 2008 Nutr Metab Cardiovasc Dis 20 4 2010 284 294
-
(2010)
Nutr Metab Cardiovasc Dis
, vol.20
, Issue.4
, pp. 284-294
-
-
Lopez-Miranda, J.1
Perez-Jimenez, F.2
Ros, E.3
De Caterina, R.4
Badimon, L.5
Covas, M.I.6
-
158
-
-
12344285031
-
Macronutrients, fatty acids, cholesterol and prostate cancer risk
-
DOI 10.1093/annonc/mdi010
-
E. Bidoli, R. Talamini, C. Bosetti, E. Negri, D. Maruzzi, and M. Montella Macronutrients, fatty acids, cholesterol and prostate cancer risk Ann Oncol 16 1 2005 152 157 (Pubitemid 40124493)
-
(2005)
Annals of Oncology
, vol.16
, Issue.1
, pp. 152-157
-
-
Bidoli, E.1
Talamini, R.2
Bosetti, C.3
Negri, E.4
Maruzzi, D.5
Montella, M.6
Franceschi, S.7
La Vecchia, C.8
-
159
-
-
77955661980
-
Diet and prostate cancer: Mechanisms of action and implications for chemoprevention
-
V. Venkateswaran, and L.H. Klotz Diet and prostate cancer: mechanisms of action and implications for chemoprevention Nat Rev Urol 7 8 2010 442 453
-
(2010)
Nat Rev Urol
, vol.7
, Issue.8
, pp. 442-453
-
-
Venkateswaran, V.1
Klotz, L.H.2
-
160
-
-
83855162786
-
Polyunsaturated fatty acid metabolism in prostate cancer
-
I.M. Berquin, I.J. Edwards, S.J. Kridel, and Y.Q. Chen Polyunsaturated fatty acid metabolism in prostate cancer Cancer Metastasis Rev 30 3-4 2011 295 309
-
(2011)
Cancer Metastasis Rev
, vol.30
, Issue.34
, pp. 295-309
-
-
Berquin, I.M.1
Edwards, I.J.2
Kridel, S.J.3
Chen, Y.Q.4
-
161
-
-
27244445146
-
Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults
-
DOI 10.1051/rnd:2005047
-
G.C. Burdge, and P.C. Calder Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults Reprod Nutr Dev 45 5 2005 581 597 (Pubitemid 41511883)
-
(2005)
Reproduction Nutrition Development
, vol.45
, Issue.5
, pp. 581-597
-
-
Burdge, G.C.1
Calder, P.C.2
-
162
-
-
51349137876
-
Multi-targeted therapy of cancer by omega-3 fatty acids
-
I.M. Berquin, I.J. Edwards, and Y.Q. Chen Multi-targeted therapy of cancer by omega-3 fatty acids Cancer Lett 269 2 2008 363 377
-
(2008)
Cancer Lett
, vol.269
, Issue.2
, pp. 363-377
-
-
Berquin, I.M.1
Edwards, I.J.2
Chen, Y.Q.3
-
163
-
-
36148990640
-
Dietary fat-gene interactions in cancer
-
DOI 10.1007/s10555-007-9075-x, Forty Years of Metastasis Research: A Tribute to Dr. Isaiah J. Fidler
-
Y.Q. Chen, I.J. Edwards, S.J. Kridel, T. Thornburg, and I.M. Berquin Dietary fat-gene interactions in cancer Cancer Metastasis Rev 26 3-4 2007 535 551 (Pubitemid 350115105)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.3-4
, pp. 535-551
-
-
Chen, Y.Q.1
Edwards, I.J.2
Kridel, S.J.3
Thornburg, T.4
Berquin, I.M.5
-
164
-
-
84857016714
-
Multiple roles of dihomo-gamma-linolenic acid against proliferation diseases
-
X. Wang, H. Lin, and Y. Gu Multiple roles of dihomo-gamma-linolenic acid against proliferation diseases Lipids Health Dis 11 1 2012 25
-
(2012)
Lipids Health Dis
, vol.11
, Issue.1
, pp. 25
-
-
Wang, X.1
Lin, H.2
Gu, Y.3
-
165
-
-
0016766826
-
Studies to determine the role rates of chain elongation and desaturation play in regulating the unsaturated fatty acid composition of rat liver lipids
-
J.T. Bernert Jr., and H. Sprecher Studies to determine the role rates of chain elongation and desaturation play in regulating the unsaturated fatty acid composition of rat liver lipids Biochim Biophys Acta 398 3 1975 354 363
-
(1975)
Biochim Biophys Acta
, vol.398
, Issue.3
, pp. 354-363
-
-
Bernert, Jr.J.T.1
Sprecher, H.2
-
166
-
-
80053148792
-
Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid
-
W. Zhang, B. Chakravarty, F. Zheng, Z. Gu, H. Wu, and J. Mao Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid Proc Natl Acad Sci U S A 108 38 2011 15757 15762
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.38
, pp. 15757-15762
-
-
Zhang, W.1
Chakravarty, B.2
Zheng, F.3
Gu, Z.4
Wu, H.5
Mao, J.6
-
167
-
-
79551626462
-
A high ratio of dietary n-6/n-3 polyunsaturated fatty acids is associated with increased risk of prostate cancer
-
C.D. Williams, B.M. Whitley, C. Hoyo, D.J. Grant, J.D. Iraggi, and K.A. Newman A high ratio of dietary n-6/n-3 polyunsaturated fatty acids is associated with increased risk of prostate cancer Nutr Res 31 1 2011 1 8
-
(2011)
Nutr Res
, vol.31
, Issue.1
, pp. 1-8
-
-
Williams, C.D.1
Whitley, B.M.2
Hoyo, C.3
Grant, D.J.4
Iraggi, J.D.5
Newman, K.A.6
-
168
-
-
34447121230
-
Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids
-
DOI 10.1172/JCI31494
-
I.M. Berquin, Y. Min, R. Wu, J. Wu, D. Perry, and J.M. Cline Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids J Clin Invest 117 7 2007 1866 1875 (Pubitemid 47036320)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.7
, pp. 1866-1875
-
-
Berquin, I.M.1
Min, Y.2
Wu, R.3
Wu, J.4
Perry, D.5
Cline, J.M.6
Thomas, M.J.7
Thornburg, T.8
Kulik, G.9
Smith, A.10
Edwards, I.J.11
D'Agostino Jr., R.12
Zhang, H.13
Wu, H.14
Kang, J.X.15
Chen, Y.Q.16
-
169
-
-
33748090269
-
2
-
DOI 10.1158/1078-0432.CCR-06-0459
-
N. Kobayashi, R.J. Barnard, S.M. Henning, D. Elashoff, S.T. Reddy, and P. Cohen Effect of altering dietary omega-6/omega-3 fatty acid ratios on prostate cancer membrane composition, cyclooxygenase-2, and prostaglandin E2 Clin Cancer Res 12 15 2006 4662 4670 (Pubitemid 44297819)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.15
, pp. 4662-4670
-
-
Kobayashi, N.1
Barnard, R.J.2
Henning, S.M.3
Elashoff, D.4
Reddy, S.T.5
Cohen, P.6
Leung, P.7
Hong-Gonzalez, J.8
Freedland, S.J.9
Said, J.10
Gui, D.11
Seeram, N.P.12
Popoviciu, L.M.13
Bagga, D.14
Heber, D.15
Glaspy, J.A.16
Aronson, W.J.17
-
170
-
-
84855393665
-
Consumption of high omega-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice
-
J.A. Akinsete, G. Ion, T.R. Witte, and W.E. Hardman Consumption of high omega-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice Carcinogenesis 33 1 2012 140 148
-
(2012)
Carcinogenesis
, vol.33
, Issue.1
, pp. 140-148
-
-
Akinsete, J.A.1
Ion, G.2
Witte, T.R.3
Hardman, W.E.4
|