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Volumn 269, Issue 2, 2008, Pages 363-377

Multi-targeted therapy of cancer by omega-3 fatty acids

Author keywords

Cancer; Dietary fat; Omega 3; Omega 6; PUFA

Indexed keywords

LONG CHAIN FATTY ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID;

EID: 51349137876     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.03.044     Document Type: Review
Times cited : (339)

References (127)
  • 1
    • 0032819001 scopus 로고    scopus 로고
    • Essential fatty acids in health and chronic disease
    • Simopoulos A.P. Essential fatty acids in health and chronic disease. Am. J. Clin. Nutr. 70 (1999) 560S-569S
    • (1999) Am. J. Clin. Nutr. , vol.70
    • Simopoulos, A.P.1
  • 2
    • 0036776120 scopus 로고    scopus 로고
    • The importance of the ratio of omega-6/omega-3 essential fatty acids
    • Simopoulos A.P. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed. Pharmacother. 56 (2002) 365-379
    • (2002) Biomed. Pharmacother. , vol.56 , pp. 365-379
    • Simopoulos, A.P.1
  • 3
    • 51349147324 scopus 로고    scopus 로고
    • C. Wang, M. Chung, E. Balk, B. Kupelnick, D. DeVine, A. Lawrence, A. Lichtenstein, J. Lau, Effects of omega-3 fatty acids on cardiovascular disease, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 94, 2004. Available from: .
    • C. Wang, M. Chung, E. Balk, B. Kupelnick, D. DeVine, A. Lawrence, A. Lichtenstein, J. Lau, Effects of omega-3 fatty acids on cardiovascular disease, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 94, 2004. Available from: .
  • 4
    • 51349166870 scopus 로고    scopus 로고
    • C.H. MacLean, A. Issa, P. Khanna, Y. Lim, W.A. Mojica, S.J. Newberry, S.C. Morton, M. Suttorp, W. Tu, L.G. Hilton, et al., Effects of omega-3 fatty acids on cancer, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 113, 2005. Available from: .
    • C.H. MacLean, A. Issa, P. Khanna, Y. Lim, W.A. Mojica, S.J. Newberry, S.C. Morton, M. Suttorp, W. Tu, L.G. Hilton, et al., Effects of omega-3 fatty acids on cancer, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 113, 2005. Available from: .
  • 5
    • 51349104657 scopus 로고    scopus 로고
    • P.G. Shekelle, S.C. Morton, C.H. MacLean, R.H. Garland, W. Tu, L.K. Jungvig, W.A. Mojica, J. Pencharz, J. Grossman, P. Khanna, et al., Effects of omega-3 fatty acids on lipids and glycemic control in type II diabetes and the metabolic syndrome and on inflammatory bowel disease, rheumatoid arthritis, renal disease, systemic lupus erythematosus, and osteoporosis, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 89, 2004. Available from: .
    • P.G. Shekelle, S.C. Morton, C.H. MacLean, R.H. Garland, W. Tu, L.K. Jungvig, W.A. Mojica, J. Pencharz, J. Grossman, P. Khanna, et al., Effects of omega-3 fatty acids on lipids and glycemic control in type II diabetes and the metabolic syndrome and on inflammatory bowel disease, rheumatoid arthritis, renal disease, systemic lupus erythematosus, and osteoporosis, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 89, 2004. Available from: .
  • 6
    • 2342518735 scopus 로고    scopus 로고
    • E. Balk, M. Chung, A. Lichtenstein, P. Chew, B. Kupelnick, A. Lawrence, D. DeVine, J. Lau, Effects of omega-3 fatty acids on cardiovascular risk factors and intermediate markers of cardiovascular disease, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 93, 2004, Available from: .
    • E. Balk, M. Chung, A. Lichtenstein, P. Chew, B. Kupelnick, A. Lawrence, D. DeVine, J. Lau, Effects of omega-3 fatty acids on cardiovascular risk factors and intermediate markers of cardiovascular disease, U.S. Department of Health and Human Services Evidence Report/Technology Assessment, 93, 2004, Available from: .
  • 7
    • 35548963388 scopus 로고    scopus 로고
    • Fish oils and vascular disease prevention: an update
    • Tziomalos K., Athyros V.G., and Mikhailidis D.P. Fish oils and vascular disease prevention: an update. Curr. Med. Chem. 14 (2007) 2622-2628
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2622-2628
    • Tziomalos, K.1    Athyros, V.G.2    Mikhailidis, D.P.3
  • 8
    • 34548538155 scopus 로고    scopus 로고
    • Beyond lipids: the role of omega-3 fatty acids from fish oil in the prevention of coronary heart disease
    • Jacobson T.A. Beyond lipids: the role of omega-3 fatty acids from fish oil in the prevention of coronary heart disease. Curr. Atheroscler. Rep. 9 (2007) 145-153
    • (2007) Curr. Atheroscler. Rep. , vol.9 , pp. 145-153
    • Jacobson, T.A.1
  • 10
    • 36049025499 scopus 로고    scopus 로고
    • The role of consumption of alpha-linolenic, eicosapentaenoic and docosahexaenoic acids in human metabolic syndrome and type 2 diabetes - a mini-review
    • Barre D.E. The role of consumption of alpha-linolenic, eicosapentaenoic and docosahexaenoic acids in human metabolic syndrome and type 2 diabetes - a mini-review. J. Oleo. Sci. 56 (2007) 319-325
    • (2007) J. Oleo. Sci. , vol.56 , pp. 319-325
    • Barre, D.E.1
  • 12
    • 0030861705 scopus 로고    scopus 로고
    • Fish oils and human diet
    • Sargent J.R. Fish oils and human diet. Br. J. Nutr. 78 Suppl. 1 (1997) S5-S13
    • (1997) Br. J. Nutr. , vol.78 , Issue.SUPPL. 1
    • Sargent, J.R.1
  • 13
    • 3042767902 scopus 로고    scopus 로고
    • Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms
    • Larsson S.C., Kumlin M., Ingelman-Sundberg M., and Wolk A. Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms. Am. J. Clin. Nutr. 79 (2004) 935-945
    • (2004) Am. J. Clin. Nutr. , vol.79 , pp. 935-945
    • Larsson, S.C.1    Kumlin, M.2    Ingelman-Sundberg, M.3    Wolk, A.4
  • 14
    • 0026718581 scopus 로고
    • The role of dietary fatty acids in biology: their place in the evolution of the human brain
    • Crawford M.A. The role of dietary fatty acids in biology: their place in the evolution of the human brain. Nutr. Rev. 50 (1992) 3-11
    • (1992) Nutr. Rev. , vol.50 , pp. 3-11
    • Crawford, M.A.1
  • 15
    • 0026750489 scopus 로고
    • Nutritional and medical importance of gamma-linolenic acid
    • Horrobin D.F. Nutritional and medical importance of gamma-linolenic acid. Prog. Lipid Res. 31 (1992) 163-194
    • (1992) Prog. Lipid Res. , vol.31 , pp. 163-194
    • Horrobin, D.F.1
  • 16
    • 0035943661 scopus 로고    scopus 로고
    • Identification of a Delta 4 fatty acid desaturase from Thraustochytrium sp. involved in the biosynthesis of docosahexanoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea
    • Qiu X., Hong H., and MacKenzie S.L. Identification of a Delta 4 fatty acid desaturase from Thraustochytrium sp. involved in the biosynthesis of docosahexanoic acid by heterologous expression in Saccharomyces cerevisiae and Brassica juncea. J. Biol. Chem. 276 (2001) 31561-31566
    • (2001) J. Biol. Chem. , vol.276 , pp. 31561-31566
    • Qiu, X.1    Hong, H.2    MacKenzie, S.L.3
  • 17
    • 0034686664 scopus 로고    scopus 로고
    • Metabolism of highly unsaturated n-3 and n-6 fatty acids
    • Sprecher H. Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim. Biophys. Acta 1486 (2000) 219-231
    • (2000) Biochim. Biophys. Acta , vol.1486 , pp. 219-231
    • Sprecher, H.1
  • 18
    • 32944467555 scopus 로고    scopus 로고
    • Long-chain n-3 PUFA: plant v. marine sources
    • Williams C.M., and Burdge G. Long-chain n-3 PUFA: plant v. marine sources. Proc. Nutr. Soc. 65 (2006) 42-50
    • (2006) Proc. Nutr. Soc. , vol.65 , pp. 42-50
    • Williams, C.M.1    Burdge, G.2
  • 19
    • 0037214197 scopus 로고    scopus 로고
    • Supplementing lactating women with flaxseed oil does not increase docosahexaenoic acid in their milk
    • Francois C.A., Connor S.L., Bolewicz L.C., and Connor W.E. Supplementing lactating women with flaxseed oil does not increase docosahexaenoic acid in their milk. Am. J. Clin. Nutr. 77 (2003) 226-233
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 226-233
    • Francois, C.A.1    Connor, S.L.2    Bolewicz, L.C.3    Connor, W.E.4
  • 20
    • 0034884757 scopus 로고    scopus 로고
    • Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans
    • Pawlosky R.J., Hibbeln J.R., Novotny J.A., and Salem Jr. N. Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans. J. Lipid Res. 42 (2001) 1257-1265
    • (2001) J. Lipid Res. , vol.42 , pp. 1257-1265
    • Pawlosky, R.J.1    Hibbeln, J.R.2    Novotny, J.A.3    Salem Jr., N.4
  • 21
    • 34548150764 scopus 로고    scopus 로고
    • Competition between 24:5n-3 and ALA for Delta 6 desaturase may limit the accumulation of DHA in HepG2 cell membranes
    • Portolesi R., Powell B.C., and Gibson R.A. Competition between 24:5n-3 and ALA for Delta 6 desaturase may limit the accumulation of DHA in HepG2 cell membranes. J. Lipid Res. 48 (2007) 1592-1598
    • (2007) J. Lipid Res. , vol.48 , pp. 1592-1598
    • Portolesi, R.1    Powell, B.C.2    Gibson, R.A.3
  • 22
    • 0029938081 scopus 로고    scopus 로고
    • Biosynthesis of docosahexaenoic acid in human cells: evidence that two different delta 6-desaturase activities may exist
    • Marzo I., Alava M.A., Pineiro A., and Naval J. Biosynthesis of docosahexaenoic acid in human cells: evidence that two different delta 6-desaturase activities may exist. Biochim. Biophys. Acta 1301 (1996) 263-272
    • (1996) Biochim. Biophys. Acta , vol.1301 , pp. 263-272
    • Marzo, I.1    Alava, M.A.2    Pineiro, A.3    Naval, J.4
  • 23
    • 0038281520 scopus 로고    scopus 로고
    • Omega-3 fatty acid supplementation accelerates chylomicron triglyceride clearance
    • Park Y., and Harris W.S. Omega-3 fatty acid supplementation accelerates chylomicron triglyceride clearance. J. Lipid Res. 44 (2003) 455-463
    • (2003) J. Lipid Res. , vol.44 , pp. 455-463
    • Park, Y.1    Harris, W.S.2
  • 24
    • 42349114775 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells
    • Sun H., Berquin I.M., Owens R.T., O'Flaherty J.T., and Edwards I.J. Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells. Cancer Res. 68 (2008) 2912-2919
    • (2008) Cancer Res. , vol.68 , pp. 2912-2919
    • Sun, H.1    Berquin, I.M.2    Owens, R.T.3    O'Flaherty, J.T.4    Edwards, I.J.5
  • 25
    • 33746809138 scopus 로고    scopus 로고
    • Distribution, interconversion, and dose response of n-3 fatty acids in humans
    • Arterburn L.M., Hall E.B., and Oken H. Distribution, interconversion, and dose response of n-3 fatty acids in humans. Am. J. Clin. Nutr. 83 (2006) 1467S-1476S
    • (2006) Am. J. Clin. Nutr. , vol.83
    • Arterburn, L.M.1    Hall, E.B.2    Oken, H.3
  • 26
    • 0037373087 scopus 로고    scopus 로고
    • Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: a review of the epidemiologic evidence
    • Terry P.D., Rohan T.E., and Wolk A. Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: a review of the epidemiologic evidence. Am. J. Clin. Nutr. 77 (2003) 532-543
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 532-543
    • Terry, P.D.1    Rohan, T.E.2    Wolk, A.3
  • 29
  • 32
    • 33845309431 scopus 로고    scopus 로고
    • Dietary fatty acids correlate with prostate cancer biopsy grade and volume in Jamaican men
    • discussion 101
    • Ritch C.R., Wan R.L., Stephens L.B., Taxy J.B., Huo D., Gong E.M., Zagaja G.P., and Brendler C.B. Dietary fatty acids correlate with prostate cancer biopsy grade and volume in Jamaican men. J. Urol. 177 (2007) 97-101 discussion 101
    • (2007) J. Urol. , vol.177 , pp. 97-101
    • Ritch, C.R.1    Wan, R.L.2    Stephens, L.B.3    Taxy, J.B.4    Huo, D.5    Gong, E.M.6    Zagaja, G.P.7    Brendler, C.B.8
  • 35
    • 2642569348 scopus 로고    scopus 로고
    • Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: the Singapore Chinese Health Study
    • Koh W.P., Yuan J.M., van den Berg D., Lee H.P., and Yu M.C. Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: the Singapore Chinese Health Study. Br. J. Cancer 90 (2004) 1760-1764
    • (2004) Br. J. Cancer , vol.90 , pp. 1760-1764
    • Koh, W.P.1    Yuan, J.M.2    van den Berg, D.3    Lee, H.P.4    Yu, M.C.5
  • 36
    • 13844266136 scopus 로고    scopus 로고
    • Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption
    • Siezen C.L., van Leeuwen A.I., Kram N.R., Luken M.E., van Kranen H.J., and Kampman E. Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption. Carcinogenesis 26 (2005) 449-457
    • (2005) Carcinogenesis , vol.26 , pp. 449-457
    • Siezen, C.L.1    van Leeuwen, A.I.2    Kram, N.R.3    Luken, M.E.4    van Kranen, H.J.5    Kampman, E.6
  • 40
    • 0024564627 scopus 로고
    • Effects of d,l-2-difluoromethylornithine and indomethacin on mammary tumor promotion in rats fed high n-3 and/or n-6 fat diets
    • Abou-el-Ela S.H., Prasse K.W., Farrell R.L., Carroll R.W., Wade A.E., and Bunce O.R. Effects of d,l-2-difluoromethylornithine and indomethacin on mammary tumor promotion in rats fed high n-3 and/or n-6 fat diets. Cancer Res. 49 (1989) 1434-1440
    • (1989) Cancer Res. , vol.49 , pp. 1434-1440
    • Abou-el-Ela, S.H.1    Prasse, K.W.2    Farrell, R.L.3    Carroll, R.W.4    Wade, A.E.5    Bunce, O.R.6
  • 41
    • 0025201334 scopus 로고
    • Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture
    • Rose D.P., and Connolly J.M. Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture. Cancer Res. 50 (1990) 7139-7144
    • (1990) Cancer Res. , vol.50 , pp. 7139-7144
    • Rose, D.P.1    Connolly, J.M.2
  • 42
    • 33645296034 scopus 로고    scopus 로고
    • Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs
    • Brown M.D., Hart C.A., Gazi E., Bagley S., and Clarke N.W. Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs. Br. J. Cancer 94 (2006) 842-853
    • (2006) Br. J. Cancer , vol.94 , pp. 842-853
    • Brown, M.D.1    Hart, C.A.2    Gazi, E.3    Bagley, S.4    Clarke, N.W.5
  • 43
    • 0029978333 scopus 로고    scopus 로고
    • Fish oil may impede tumour angiogenesis and invasiveness by down-regulating protein kinase C and modulating eicosanoid production
    • McCarty M.F. Fish oil may impede tumour angiogenesis and invasiveness by down-regulating protein kinase C and modulating eicosanoid production. Med. Hypotheses 46 (1996) 107-115
    • (1996) Med. Hypotheses , vol.46 , pp. 107-115
    • McCarty, M.F.1
  • 44
    • 0033637473 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by dietary fatty acids and eicosanoids
    • Rose D.P., and Connolly J.M. Regulation of tumor angiogenesis by dietary fatty acids and eicosanoids. Nutr. Cancer 37 (2000) 119-127
    • (2000) Nutr. Cancer , vol.37 , pp. 119-127
    • Rose, D.P.1    Connolly, J.M.2
  • 45
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • Serhan C.N., Hong S., Gronert K., Colgan S.P., Devchand P.R., Mirick G., and Moussignac R.L. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med. 196 (2002) 1025-1037
    • (2002) J. Exp. Med. , vol.196 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3    Colgan, S.P.4    Devchand, P.R.5    Mirick, G.6    Moussignac, R.L.7
  • 46
    • 12344253802 scopus 로고    scopus 로고
    • Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers
    • Serhan C.N., Arita M., Hong S., and Gotlinger K. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers. Lipids 39 (2004) 1125-1132
    • (2004) Lipids , vol.39 , pp. 1125-1132
    • Serhan, C.N.1    Arita, M.2    Hong, S.3    Gotlinger, K.4
  • 47
    • 30044449982 scopus 로고    scopus 로고
    • Resolution of inflammation: the beginning programs the end
    • Serhan C.N., and Savill J. Resolution of inflammation: the beginning programs the end. Nat. Immunol. 6 (2005) 1191-1197
    • (2005) Nat. Immunol. , vol.6 , pp. 1191-1197
    • Serhan, C.N.1    Savill, J.2
  • 48
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., and Werb Z. Inflammation and cancer. Nature 420 (2002) 860-867
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 49
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 441 (2006) 431-436
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 50
    • 4544243747 scopus 로고    scopus 로고
    • At the crossroads of inflammation and cancer
    • Clevers H. At the crossroads of inflammation and cancer. Cell 118 (2004) 671-674
    • (2004) Cell , vol.118 , pp. 671-674
    • Clevers, H.1
  • 51
    • 0001599097 scopus 로고
    • Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties
    • Needleman P., Raz A., Minkes M.S., Ferrendelli J.A., and Sprecher H. Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties. Proc. Natl. Acad. Sci. USA 76 (1979) 944-948
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 944-948
    • Needleman, P.1    Raz, A.2    Minkes, M.S.3    Ferrendelli, J.A.4    Sprecher, H.5
  • 52
    • 34547958615 scopus 로고    scopus 로고
    • Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products
    • Wada M., DeLong C.J., Hong Y.H., Rieke C.J., Song I., Sidhu R.S., Yuan C., Warnock M., Schmaier A.H., Yokoyama C., et al. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. J. Biol. Chem. 282 (2007) 22254-22266
    • (2007) J. Biol. Chem. , vol.282 , pp. 22254-22266
    • Wada, M.1    DeLong, C.J.2    Hong, Y.H.3    Rieke, C.J.4    Song, I.5    Sidhu, R.S.6    Yuan, C.7    Warnock, M.8    Schmaier, A.H.9    Yokoyama, C.10
  • 53
    • 0029994786 scopus 로고    scopus 로고
    • Effect of amount and types of dietary fat on intestinal bacterial 7 alpha-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during stages of colon tumor promotion
    • Reddy B.S., Simi B., Patel N., Aliaga C., and Rao C.V. Effect of amount and types of dietary fat on intestinal bacterial 7 alpha-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during stages of colon tumor promotion. Cancer Res. 56 (1996) 2314-2320
    • (1996) Cancer Res. , vol.56 , pp. 2314-2320
    • Reddy, B.S.1    Simi, B.2    Patel, N.3    Aliaga, C.4    Rao, C.V.5
  • 54
    • 0031022228 scopus 로고    scopus 로고
    • Dietary fat and colon cancer: modulating effect of types and amount of dietary fat on ras-p21 function during promotion and progression stages of colon cancer
    • Singh J., Hamid R., and Reddy B.S. Dietary fat and colon cancer: modulating effect of types and amount of dietary fat on ras-p21 function during promotion and progression stages of colon cancer. Cancer Res. 57 (1997) 253-258
    • (1997) Cancer Res. , vol.57 , pp. 253-258
    • Singh, J.1    Hamid, R.2    Reddy, B.S.3
  • 55
    • 0035036533 scopus 로고    scopus 로고
    • n-6 and n-3 polyunsaturated fatty acids differentially modulate oncogenic Ras activation in colonocytes
    • Collett E.D., Davidson L.A., Fan Y.Y., Lupton J.R., and Chapkin R.S. n-6 and n-3 polyunsaturated fatty acids differentially modulate oncogenic Ras activation in colonocytes. Am. J. Physiol. Cell Physiol. 280 (2001) C1066-C1075
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280
    • Collett, E.D.1    Davidson, L.A.2    Fan, Y.Y.3    Lupton, J.R.4    Chapkin, R.S.5
  • 56
    • 34548539093 scopus 로고    scopus 로고
    • Dietary factors and growth and metabolism in experimental tumors
    • Sauer L.A., Blask D.E., and Dauchy R.T. Dietary factors and growth and metabolism in experimental tumors. J. Nutr. Biochem. 18 (2007) 637-649
    • (2007) J. Nutr. Biochem. , vol.18 , pp. 637-649
    • Sauer, L.A.1    Blask, D.E.2    Dauchy, R.T.3
  • 58
    • 34347408026 scopus 로고    scopus 로고
    • Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids
    • Liu Y.E., Pu W., Wang J., Kang J.X., and Shi Y.E. Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids. FEBS J. 274 (2007) 3351-3362
    • (2007) FEBS J. , vol.274 , pp. 3351-3362
    • Liu, Y.E.1    Pu, W.2    Wang, J.3    Kang, J.X.4    Shi, Y.E.5
  • 60
    • 33745128696 scopus 로고    scopus 로고
    • How dietary arachidonic- and docosahexaenoic-acid rich oils differentially affect the murine hepatic transcriptome
    • Berger A., Roberts M.A., and Hoff B. How dietary arachidonic- and docosahexaenoic-acid rich oils differentially affect the murine hepatic transcriptome. Lipids Health Dis. 5 (2006) 10
    • (2006) Lipids Health Dis. , vol.5 , pp. 10
    • Berger, A.1    Roberts, M.A.2    Hoff, B.3
  • 61
    • 7644222841 scopus 로고    scopus 로고
    • Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation
    • Wassall S.R., Brzustowicz M.R., Shaikh S.R., Cherezov V., Caffrey M., and Stillwell W. Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation. Chem. Phys. Lipids 132 (2004) 79-88
    • (2004) Chem. Phys. Lipids , vol.132 , pp. 79-88
    • Wassall, S.R.1    Brzustowicz, M.R.2    Shaikh, S.R.3    Cherezov, V.4    Caffrey, M.5    Stillwell, W.6
  • 62
    • 33947169954 scopus 로고    scopus 로고
    • (n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells
    • Schley P.D., Brindley D.N., and Field C.J. (n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells. J. Nutr. 137 (2007) 548-553
    • (2007) J. Nutr. , vol.137 , pp. 548-553
    • Schley, P.D.1    Brindley, D.N.2    Field, C.J.3
  • 63
    • 0036212979 scopus 로고    scopus 로고
    • N-3 fatty acids and lipid peroxidation in breast cancer inhibition
    • Stoll B.A. N-3 fatty acids and lipid peroxidation in breast cancer inhibition. Br. J. Nutr. 87 (2002) 193-198
    • (2002) Br. J. Nutr. , vol.87 , pp. 193-198
    • Stoll, B.A.1
  • 64
    • 0141590658 scopus 로고    scopus 로고
    • Chemopreventive n-3 fatty acids activate RXRalpha in colonocytes
    • Fan Y.Y., Spencer T.E., Wang N., Moyer M.P., and Chapkin R.S. Chemopreventive n-3 fatty acids activate RXRalpha in colonocytes. Carcinogenesis 24 (2003) 1541-1548
    • (2003) Carcinogenesis , vol.24 , pp. 1541-1548
    • Fan, Y.Y.1    Spencer, T.E.2    Wang, N.3    Moyer, M.P.4    Chapkin, R.S.5
  • 67
    • 4444261390 scopus 로고    scopus 로고
    • Translational regulation of gene expression by omega-3 fatty acids
    • Aktas H., and Halperin J.A. Translational regulation of gene expression by omega-3 fatty acids. J. Nutr. 134 (2004) 2487S-2491S
    • (2004) J. Nutr. , vol.134
    • Aktas, H.1    Halperin, J.A.2
  • 68
    • 0028919628 scopus 로고
    • Review of the effects of dietary fat on experimental mammary gland tumorigenesis: role of lipid peroxidation
    • Welsch C.W. Review of the effects of dietary fat on experimental mammary gland tumorigenesis: role of lipid peroxidation. Free. Radic. Biol. Med. 18 (1995) 757-773
    • (1995) Free. Radic. Biol. Med. , vol.18 , pp. 757-773
    • Welsch, C.W.1
  • 69
  • 70
    • 0023894552 scopus 로고
    • Effects of dietary menhaden oil and retinyl acetate on the growth of DU 145 human prostatic adenocarcinoma cells transplanted into athymic nude mice
    • Rose D.P., and Cohen L.A. Effects of dietary menhaden oil and retinyl acetate on the growth of DU 145 human prostatic adenocarcinoma cells transplanted into athymic nude mice. Carcinogenesis 9 (1988) 603-605
    • (1988) Carcinogenesis , vol.9 , pp. 603-605
    • Rose, D.P.1    Cohen, L.A.2
  • 72
    • 0021884739 scopus 로고
    • Effect of dietary fat on growth kinetics of transplantable mammary adenocarcinoma in BALB/c mice
    • Gabor H., Hillyard L.A., and Abraham S. Effect of dietary fat on growth kinetics of transplantable mammary adenocarcinoma in BALB/c mice. J. Natl. Cancer Inst. 74 (1985) 1299-1305
    • (1985) J. Natl. Cancer Inst. , vol.74 , pp. 1299-1305
    • Gabor, H.1    Hillyard, L.A.2    Abraham, S.3
  • 73
    • 0027370753 scopus 로고
    • Effects of dietary omega-3 fatty acids on human breast cancer growth and metastases in nude mice
    • Rose D.P., and Connolly J.M. Effects of dietary omega-3 fatty acids on human breast cancer growth and metastases in nude mice. J. Natl. Cancer Inst. 85 (1993) 1743-1747
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1743-1747
    • Rose, D.P.1    Connolly, J.M.2
  • 74
    • 0028906908 scopus 로고
    • Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice
    • Rose D.P., Connolly J.M., Rayburn J., and Coleman M. Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice. J. Natl. Cancer Inst. 87 (1995) 587-592
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 587-592
    • Rose, D.P.1    Connolly, J.M.2    Rayburn, J.3    Coleman, M.4
  • 75
    • 0021800764 scopus 로고
    • Dietary effects of menhaden oil on the growth and membrane lipid composition of rat mammary tumors
    • Jurkowski J.J., and Cave Jr. W.T. Dietary effects of menhaden oil on the growth and membrane lipid composition of rat mammary tumors. J. Natl. Cancer Inst. 74 (1985) 1145-1150
    • (1985) J. Natl. Cancer Inst. , vol.74 , pp. 1145-1150
    • Jurkowski, J.J.1    Cave Jr., W.T.2
  • 76
    • 0022653692 scopus 로고
    • Dietary polyunsaturated fat in relation to mammary carcinogenesis in rats
    • Braden L.M., and Carroll K.K. Dietary polyunsaturated fat in relation to mammary carcinogenesis in rats. Lipids 21 (1986) 285-288
    • (1986) Lipids , vol.21 , pp. 285-288
    • Braden, L.M.1    Carroll, K.K.2
  • 79
    • 0034772877 scopus 로고    scopus 로고
    • Three percent dietary fish oil concentrate increased efficacy of doxorubicin against MDA-MB 231 breast cancer xenografts
    • Hardman W.E., Avula C.P., Fernandes G., and Cameron I.L. Three percent dietary fish oil concentrate increased efficacy of doxorubicin against MDA-MB 231 breast cancer xenografts. Clin. Cancer Res. 7 (2001) 2041-2049
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2041-2049
    • Hardman, W.E.1    Avula, C.P.2    Fernandes, G.3    Cameron, I.L.4
  • 80
    • 0028821851 scopus 로고
    • Dietary menhaden oil enhances mitomycin C antitumor activity toward human mammary carcinoma MX-1
    • Shao Y., Pardini L., and Pardini R.S. Dietary menhaden oil enhances mitomycin C antitumor activity toward human mammary carcinoma MX-1. Lipids 30 (1995) 1035-1045
    • (1995) Lipids , vol.30 , pp. 1035-1045
    • Shao, Y.1    Pardini, L.2    Pardini, R.S.3
  • 81
    • 9344238812 scopus 로고    scopus 로고
    • Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice
    • Chen J., Hui E., Ip T., and Thompson L.U. Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice. Clin. Cancer Res. 10 (2004) 7703-7711
    • (2004) Clin. Cancer Res. , vol.10 , pp. 7703-7711
    • Chen, J.1    Hui, E.2    Ip, T.3    Thompson, L.U.4
  • 82
    • 33747060171 scopus 로고    scopus 로고
    • Nutritional intervention with omega-3 fatty acids enhances tumor response to anti-neoplastic agents
    • Pardini R.S. Nutritional intervention with omega-3 fatty acids enhances tumor response to anti-neoplastic agents. Chem. Biol. Interact. 162 (2006) 89-105
    • (2006) Chem. Biol. Interact. , vol.162 , pp. 89-105
    • Pardini, R.S.1
  • 83
    • 0024359924 scopus 로고
    • Postpromotional effects of dietary marine or safflower oils on large bowel or pulmonary implants of CT-26 in mice
    • Cannizzo Jr. F., and Broitman S.A. Postpromotional effects of dietary marine or safflower oils on large bowel or pulmonary implants of CT-26 in mice. Cancer Res. 49 (1989) 4289-4294
    • (1989) Cancer Res. , vol.49 , pp. 4289-4294
    • Cannizzo Jr., F.1    Broitman, S.A.2
  • 85
    • 0031417628 scopus 로고    scopus 로고
    • A fish oil derived concentrate enriched in eicosapentaenoic and docosahexaenoic acid as ethyl ester suppresses the formation and growth of intestinal polyps in the Min mouse
    • Paulsen J.E., Elvsaas I.K., Steffensen I.L., and Alexander J. A fish oil derived concentrate enriched in eicosapentaenoic and docosahexaenoic acid as ethyl ester suppresses the formation and growth of intestinal polyps in the Min mouse. Carcinogenesis 18 (1997) 1905-1910
    • (1997) Carcinogenesis , vol.18 , pp. 1905-1910
    • Paulsen, J.E.1    Elvsaas, I.K.2    Steffensen, I.L.3    Alexander, J.4
  • 86
    • 0035866384 scopus 로고    scopus 로고
    • Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways
    • Boudreau M.D., Sohn K.H., Rhee S.H., Lee S.W., Hunt J.D., and Hwang D.H. Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways. Cancer Res. 61 (2001) 1386-1391
    • (2001) Cancer Res. , vol.61 , pp. 1386-1391
    • Boudreau, M.D.1    Sohn, K.H.2    Rhee, S.H.3    Lee, S.W.4    Hunt, J.D.5    Hwang, D.H.6
  • 88
    • 0022637661 scopus 로고
    • Effect of dietary fish oil on azoxymethane-induced colon carcinogenesis in male F344 rats
    • Reddy B.S., and Maruyama H. Effect of dietary fish oil on azoxymethane-induced colon carcinogenesis in male F344 rats. Cancer Res. 46 (1986) 3367-3370
    • (1986) Cancer Res. , vol.46 , pp. 3367-3370
    • Reddy, B.S.1    Maruyama, H.2
  • 89
    • 0023734037 scopus 로고
    • Effect of dietary eicosapentaenoic acid on azoxymethane-induced colon carcinogenesis in rats
    • Minoura T., Takata T., Sakaguchi M., Takada H., Yamamura M., Hioki K., and Yamamoto M. Effect of dietary eicosapentaenoic acid on azoxymethane-induced colon carcinogenesis in rats. Cancer Res. 48 (1988) 4790-4794
    • (1988) Cancer Res. , vol.48 , pp. 4790-4794
    • Minoura, T.1    Takata, T.2    Sakaguchi, M.3    Takada, H.4    Yamamura, M.5    Hioki, K.6    Yamamoto, M.7
  • 90
    • 0027936114 scopus 로고
    • Effect of docosahexaenoic acid on azoxymethane-induced colon carcinogenesis in rats
    • Takahashi M., Minamoto T., Yamashita N., Kato T., Yazawa K., and Esumi H. Effect of docosahexaenoic acid on azoxymethane-induced colon carcinogenesis in rats. Cancer Lett. 83 (1994) 177-184
    • (1994) Cancer Lett. , vol.83 , pp. 177-184
    • Takahashi, M.1    Minamoto, T.2    Yamashita, N.3    Kato, T.4    Yazawa, K.5    Esumi, H.6
  • 91
    • 0031410749 scopus 로고    scopus 로고
    • Suppression of azoxymethane-induced rat colon carcinoma development by a fish oil component, docosahexaenoic acid (DHA)
    • Takahashi M., Fukutake M., Isoi T., Fukuda K., Sato H., Yazawa K., Sugimura T., and Wakabayashi K. Suppression of azoxymethane-induced rat colon carcinoma development by a fish oil component, docosahexaenoic acid (DHA). Carcinogenesis 18 (1997) 1337-1342
    • (1997) Carcinogenesis , vol.18 , pp. 1337-1342
    • Takahashi, M.1    Fukutake, M.2    Isoi, T.3    Fukuda, K.4    Sato, H.5    Yazawa, K.6    Sugimura, T.7    Wakabayashi, K.8
  • 92
    • 0028977960 scopus 로고
    • Dietary omega-3 fats reduce proliferation and tumor yields at colorectal anastomosis in rats
    • Hendrickse C.W., Keighley M.R., and Neoptolemos J.P. Dietary omega-3 fats reduce proliferation and tumor yields at colorectal anastomosis in rats. Gastroenterology 109 (1995) 431-439
    • (1995) Gastroenterology , vol.109 , pp. 431-439
    • Hendrickse, C.W.1    Keighley, M.R.2    Neoptolemos, J.P.3
  • 94
  • 95
    • 14944350980 scopus 로고    scopus 로고
    • Chemopreventive effects of dietary flaxseed oil on colon tumor development
    • Dwivedi C., Natarajan K., and Matthees D.P. Chemopreventive effects of dietary flaxseed oil on colon tumor development. Nutr. Cancer 51 (2005) 52-58
    • (2005) Nutr. Cancer , vol.51 , pp. 52-58
    • Dwivedi, C.1    Natarajan, K.2    Matthees, D.P.3
  • 96
    • 33748127203 scopus 로고    scopus 로고
    • Chemopreventive effects of dietary flaxseed on colon tumor development
    • Bommareddy A., Arasada B.L., Mathees D.P., and Dwivedi C. Chemopreventive effects of dietary flaxseed on colon tumor development. Nutr. Cancer 54 (2006) 216-222
    • (2006) Nutr. Cancer , vol.54 , pp. 216-222
    • Bommareddy, A.1    Arasada, B.L.2    Mathees, D.P.3    Dwivedi, C.4
  • 97
    • 33751345815 scopus 로고    scopus 로고
    • Flax seed oil and flax seed meal reduce the formation of aberrant crypt foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats
    • Williams D., Verghese M., Walker L.T., Boateng J., Shackelford L., and Chawan C.B. Flax seed oil and flax seed meal reduce the formation of aberrant crypt foci (ACF) in azoxymethane-induced colon cancer in Fisher 344 male rats. Food Chem. Toxicol. 45 (2007) 153-159
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 153-159
    • Williams, D.1    Verghese, M.2    Walker, L.T.3    Boateng, J.4    Shackelford, L.5    Chawan, C.B.6
  • 98
    • 0033802965 scopus 로고    scopus 로고
    • Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice
    • Petrik M.B., McEntee M.F., Johnson B.T., Obukowicz M.G., and Whelan J. Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. J. Nutr. 130 (2000) 2434-2443
    • (2000) J. Nutr. , vol.130 , pp. 2434-2443
    • Petrik, M.B.1    McEntee, M.F.2    Johnson, B.T.3    Obukowicz, M.G.4    Whelan, J.5
  • 99
    • 0035370749 scopus 로고    scopus 로고
    • The association of fatty acids with prostate cancer risk
    • Newcomer L.M., King I.B., Wicklund K.G., and Stanford J.L. The association of fatty acids with prostate cancer risk. Prostate 47 (2001) 262-268
    • (2001) Prostate , vol.47 , pp. 262-268
    • Newcomer, L.M.1    King, I.B.2    Wicklund, K.G.3    Stanford, J.L.4
  • 101
    • 2942706075 scopus 로고    scopus 로고
    • An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort
    • Jatoi A., Rowland K., Loprinzi C.L., Sloan J.A., Dakhil S.R., MacDonald N., Gagnon B., Novotny P.J., Mailliard J.A., Bushey T.I., et al. An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort. J. Clin. Oncol. 22 (2004) 2469-2476
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2469-2476
    • Jatoi, A.1    Rowland, K.2    Loprinzi, C.L.3    Sloan, J.A.4    Dakhil, S.R.5    MacDonald, N.6    Gagnon, B.7    Novotny, P.J.8    Mailliard, J.A.9    Bushey, T.I.10
  • 104
    • 31344441515 scopus 로고    scopus 로고
    • Omega-3 fatty acids for the treatment of cancer cachexia: issues in designing clinical trials of dietary supplements
    • Harle L., Brown T., Laheru D., and Dobs A.S. Omega-3 fatty acids for the treatment of cancer cachexia: issues in designing clinical trials of dietary supplements. J. Altern. Complement Med. 11 (2005) 1039-1046
    • (2005) J. Altern. Complement Med. , vol.11 , pp. 1039-1046
    • Harle, L.1    Brown, T.2    Laheru, D.3    Dobs, A.S.4
  • 105
    • 0033918233 scopus 로고    scopus 로고
    • Effect of oral eicosapentaenoic acid on weight loss in patients with pancreatic cancer
    • Wigmore S.J., Barber M.D., Ross J.A., Tisdale M.J., and Fearon K.C. Effect of oral eicosapentaenoic acid on weight loss in patients with pancreatic cancer. Nutr. Cancer 36 (2000) 177-184
    • (2000) Nutr. Cancer , vol.36 , pp. 177-184
    • Wigmore, S.J.1    Barber, M.D.2    Ross, J.A.3    Tisdale, M.J.4    Fearon, K.C.5
  • 106
    • 0031975234 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial
    • Gogos C.A., Ginopoulos P., Salsa B., Apostolidou E., Zoumbos N.C., and Kalfarentzos F. Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial. Cancer 82 (1998) 395-402
    • (1998) Cancer , vol.82 , pp. 395-402
    • Gogos, C.A.1    Ginopoulos, P.2    Salsa, B.3    Apostolidou, E.4    Zoumbos, N.C.5    Kalfarentzos, F.6
  • 108
    • 33744748305 scopus 로고    scopus 로고
    • A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress
    • Mantovani G., Maccio A., Madeddu C., Gramignano G., Lusso M.R., Serpe R., Massa E., Astara G., and Deiana L. A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress. Cancer Epidemiol. Biomarkers Prev. 15 (2006) 1030-1034
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 1030-1034
    • Mantovani, G.1    Maccio, A.2    Madeddu, C.3    Gramignano, G.4    Lusso, M.R.5    Serpe, R.6    Massa, E.7    Astara, G.8    Deiana, L.9
  • 109
    • 0037208642 scopus 로고    scopus 로고
    • Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a double-blind, placebo-controlled study
    • Bruera E., Strasser F., Palmer J.L., Willey J., Calder K., Amyotte G., and Baracos V. Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a double-blind, placebo-controlled study. J. Clin. Oncol. 21 (2003) 129-134
    • (2003) J. Clin. Oncol. , vol.21 , pp. 129-134
    • Bruera, E.1    Strasser, F.2    Palmer, J.L.3    Willey, J.4    Calder, K.5    Amyotte, G.6    Baracos, V.7
  • 110
    • 0141869044 scopus 로고    scopus 로고
    • Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial
    • Fearon K.C., Von Meyenfeldt M.F., Moses A.G., Van Geenen R., Roy A., Gouma D.J., Giacosa A., Van Gossum A., Bauer J., Barber M.D., et al. Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. Gut 52 (2003) 1479-1486
    • (2003) Gut , vol.52 , pp. 1479-1486
    • Fearon, K.C.1    Von Meyenfeldt, M.F.2    Moses, A.G.3    Van Geenen, R.4    Roy, A.5    Gouma, D.J.6    Giacosa, A.7    Van Gossum, A.8    Bauer, J.9    Barber, M.D.10
  • 111
    • 34250641243 scopus 로고    scopus 로고
    • Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia
    • Dewey A., Baughan C., Dean T., Higgins B., and Johnson I. Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia. Cochrane Database Syst. Rev. (2007) CD004597
    • (2007) Cochrane Database Syst. Rev.
    • Dewey, A.1    Baughan, C.2    Dean, T.3    Higgins, B.4    Johnson, I.5
  • 112
    • 35148818281 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer
    • Cerchietti L.C., Navigante A.H., and Castro M.A. Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. Nutr. Cancer 59 (2007) 14-20
    • (2007) Nutr. Cancer , vol.59 , pp. 14-20
    • Cerchietti, L.C.1    Navigante, A.H.2    Castro, M.A.3
  • 113
    • 38549163699 scopus 로고    scopus 로고
    • Results of a pilot study of the effects of celecoxib on cancer cachexia in patients with cancer of the head, neck, and gastrointestinal tract
    • Lai V., George J., Richey L., Kim H.J., Cannon T., Shores C., and Couch M. Results of a pilot study of the effects of celecoxib on cancer cachexia in patients with cancer of the head, neck, and gastrointestinal tract. Head Neck 30 (2008) 67-74
    • (2008) Head Neck , vol.30 , pp. 67-74
    • Lai, V.1    George, J.2    Richey, L.3    Kim, H.J.4    Cannon, T.5    Shores, C.6    Couch, M.7
  • 114
    • 19544362736 scopus 로고    scopus 로고
    • Influence of preoperative administration of omega-3 fatty acid-enriched supplement on inflammatory and immune responses in patients undergoing major surgery for cancer
    • Nakamura K., Kariyazono H., Komokata T., Hamada N., Sakata R., and Yamada K. Influence of preoperative administration of omega-3 fatty acid-enriched supplement on inflammatory and immune responses in patients undergoing major surgery for cancer. Nutrition 21 (2005) 639-649
    • (2005) Nutrition , vol.21 , pp. 639-649
    • Nakamura, K.1    Kariyazono, H.2    Komokata, T.3    Hamada, N.4    Sakata, R.5    Yamada, K.6
  • 115
    • 34047113993 scopus 로고    scopus 로고
    • Application of perioperative immunonutrition for gastrointestinal surgery: a meta-analysis of randomized controlled trials
    • Zheng Y., Li F., Qi B., Luo B., Sun H., Liu S., and Wu X. Application of perioperative immunonutrition for gastrointestinal surgery: a meta-analysis of randomized controlled trials. Asia Pac. J. Clin. Nutr. 16 Suppl. 1 (2007) 253-257
    • (2007) Asia Pac. J. Clin. Nutr. , vol.16 , Issue.SUPPL. 1 , pp. 253-257
    • Zheng, Y.1    Li, F.2    Qi, B.3    Luo, B.4    Sun, H.5    Liu, S.6    Wu, X.7
  • 116
    • 24744445635 scopus 로고    scopus 로고
    • The effects of immediate enteral feeding with a formula containing high levels of omega-3 fatty acids in patients after surgery for esophageal cancer
    • Aiko S., Yoshizumi Y., Tsuwano S., Shimanouchi M., Sugiura Y., and Maehara T. The effects of immediate enteral feeding with a formula containing high levels of omega-3 fatty acids in patients after surgery for esophageal cancer. JPEN J. Parenter. Enteral Nutr. 29 (2005) 141-147
    • (2005) JPEN J. Parenter. Enteral Nutr. , vol.29 , pp. 141-147
    • Aiko, S.1    Yoshizumi, Y.2    Tsuwano, S.3    Shimanouchi, M.4    Sugiura, Y.5    Maehara, T.6
  • 118
    • 33747067878 scopus 로고    scopus 로고
    • Docosahexaenoic acid (DHA) intake during first line chemotherapy improves survival in metastatic breast cancer
    • abstract #5276
    • Bougnoux P., Hajjaju N., Baucher M.A., Jordan M.L., Goupille C., Body G., and LeFoch O. Docosahexaenoic acid (DHA) intake during first line chemotherapy improves survival in metastatic breast cancer. Proc. Am. Assoc. Cancer Res. 47 (2006) 1237 abstract #5276
    • (2006) Proc. Am. Assoc. Cancer Res. , vol.47 , pp. 1237
    • Bougnoux, P.1    Hajjaju, N.2    Baucher, M.A.3    Jordan, M.L.4    Goupille, C.5    Body, G.6    LeFoch, O.7
  • 124
    • 0029005808 scopus 로고
    • Missing anti-proliferative effect of fish oil on rectal epithelium in healthy volunteers consuming a high-fat diet: potential role of the n-3:n-6 fatty acid ratio
    • Bartram H.P., Gostner A., Reddy B.S., Rao C.V., Scheppach W., Dusel G., Richter A., Richter F., and Kasper H. Missing anti-proliferative effect of fish oil on rectal epithelium in healthy volunteers consuming a high-fat diet: potential role of the n-3:n-6 fatty acid ratio. Eur. J. Cancer Prev. 4 (1995) 231-237
    • (1995) Eur. J. Cancer Prev. , vol.4 , pp. 231-237
    • Bartram, H.P.1    Gostner, A.2    Reddy, B.S.3    Rao, C.V.4    Scheppach, W.5    Dusel, G.6    Richter, A.7    Richter, F.8    Kasper, H.9
  • 125
    • 0034907428 scopus 로고    scopus 로고
    • Modulation of omega-3/omega-6 polyunsaturated ratios with dietary fish oils in men with prostate cancer
    • Aronson W.J., Glaspy J.A., Reddy S.T., Reese D., Heber D., and Bagga D. Modulation of omega-3/omega-6 polyunsaturated ratios with dietary fish oils in men with prostate cancer. Urology 58 (2001) 283-288
    • (2001) Urology , vol.58 , pp. 283-288
    • Aronson, W.J.1    Glaspy, J.A.2    Reddy, S.T.3    Reese, D.4    Heber, D.5    Bagga, D.6
  • 126
    • 2342559192 scopus 로고    scopus 로고
    • Pilot study to explore effects of low-fat, flaxseed-supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen
    • Demark-Wahnefried W., Robertson C.N., Walther P.J., Polascik T.J., Paulson D.F., and Vollmer R.T. Pilot study to explore effects of low-fat, flaxseed-supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen. Urology 63 (2004) 900-904
    • (2004) Urology , vol.63 , pp. 900-904
    • Demark-Wahnefried, W.1    Robertson, C.N.2    Walther, P.J.3    Polascik, T.J.4    Paulson, D.F.5    Vollmer, R.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.