Fatty Acid Synthase Inhibition Triggers Apoptosis during S Phase in Human Cancer Cells

Cancer Research

Volumn 63, Issue 21, 2003, Pages 7330-7337

  Zhou, Weibo ^a   Simpson, P Jeanette ^a   McFadden, Jill M ^b   Townsend, Craig A ^b   Medghalchi, Susan M ^c   Vadlamudi, Aravinda ^c   Pinn, Michael L ^a   Ronnett, Gabriele V ^a   Kuhajda, Francis P ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c FASgen Inc   (United States)

^d JOHNS HOPKINS BAYVIEW MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 FUROIC ACID DERIVATIVE; 5 TETRADECYLOXY 2 FUROIC ACID; BROXURIDINE; C75; CARNITINE PALMITOYLTRANSFERASE; ENZYME INHIBITOR; ETOMOXIR; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; MALONYL COENZYME A; MEMBRANE LIPID; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

APOPTOSIS; BREAST CANCER; CANCER CELL; CELL CYCLE S PHASE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; NICK END LABELING; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL;

4-BUTYROLACTONE; APOPTOSIS; BREAST NEOPLASMS; CARNITINE O-PALMITOYLTRANSFERASE; CELL DIVISION; CELL LINE, TUMOR; DRUG INTERACTIONS; EPOXY COMPOUNDS; FATTY ACID SYNTHETASE COMPLEX; FURANS; HUMANS; MEMBRANE LIPIDS; PHOSPHOLIPIDS; S PHASE;

EID: 0242694902     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

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