-
1
-
-
0031561476
-
Protein tyrosine kinases and cancer
-
Kolibaba, K. S., and Druker, B. J. Protein tyrosine kinases and cancer. Biochim. Biophys. Acta, 1333: F217-F248, 1997.
-
(1997)
Biochim. Biophys. Acta
, vol.1333
, pp. F217-F248
-
-
Kolibaba, K.S.1
Druker, B.J.2
-
2
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon, D. J., Godolphin, W., Jones, L. A., Holt, J. A., Wong, S. G., Keith, D. E., Levin, W. J., Stuart, S. G., Udove, J., Ullrich, A., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science (Wash. DC), 244: 707-712, 1989.
-
(1989)
Science (Wash. DC)
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
3
-
-
0033377721
-
Genetic alterations in ERBB2-amplified breast carcinomas
-
Isola, J., Chu, L., DeVries, S., Matsumura, K., Chew, K., Ljung, B. M., and Waldman, F. M. Genetic alterations in ERBB2-amplified breast carcinomas. Clin. Cancer Res., 5: 4140-4145, 1999.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 4140-4145
-
-
Isola, J.1
Chu, L.2
DeVries, S.3
Matsumura, K.4
Chew, K.5
Ljung, B.M.6
Waldman, F.M.7
-
4
-
-
8944232866
-
Node-negative breast cancers with p53(-)/HER2-neu(-) status may identify women with very good prognosis
-
Albanell, J., Bellmunt, J., Molina, R., Garcia, M., Caragol, I., Bermejo, B., Ribas, A., Carulla, J., Gallego, O. S., Espanol, T., and Sole Calvo, L. A. Node-negative breast cancers with p53(-)/HER2-neu(-) status may identify women with very good prognosis. Anticancer Res., 16: 1027-1032, 1996.
-
(1996)
Anticancer Res.
, vol.16
, pp. 1027-1032
-
-
Albanell, J.1
Bellmunt, J.2
Molina, R.3
Garcia, M.4
Caragol, I.5
Bermejo, B.6
Ribas, A.7
Carulla, J.8
Gallego, O.S.9
Espanol, T.10
Sole Calvo, L.A.11
-
5
-
-
0023640312
-
Proto-oncogenes and human cancers
-
Slamon, D. J. Proto-oncogenes and human cancers. N. Engl. J. Med., 317: 955-957, 1987.
-
(1987)
N. Engl. J. Med.
, vol.317
, pp. 955-957
-
-
Slamon, D.J.1
-
6
-
-
0033559606
-
Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy
-
Yang, X. D., Jia, X. C., Corvalan, J. R., Wang, P., Davis, C. G., and Jakobovits, A. Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy. Cancer Res., 59: 1236-1243, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 1236-1243
-
-
Yang, X.D.1
Jia, X.C.2
Corvalan, J.R.3
Wang, P.4
Davis, C.G.5
Jakobovits, A.6
-
7
-
-
0029991439
-
Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
Baselga, J., Tripathy, D., Mendelsohn, J., Baughman, S., Benz, C. C., Dantis, L., Sklarin, N. T., Seidman, A. D., Hudis, C. A., Moore, J., Rosen, P. P., Twaddell, T., Henderson, I. C., and Norton, L. Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J. Clin. Oncol., 14: 737-744, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twaddell, T.12
Henderson, I.C.13
Norton, L.14
-
8
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel, C. L., Cobleigh, M. A., Tripathy, D., Gutheil, J. C., Harris, L. N., Fehrenbacher, L., Slamon, D. J., Murphy, M., Novotny, W. F., Burchmore, M., Shak, S., Stewart, S. J., and Press, M. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol., 20: 719-726, 2002.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
9
-
-
0032445260
-
HER-2/neu as a predictive marker of response to breast cancer therapy
-
Pegram, M. D., Pauletti, G., and Slamon, D. J. HER-2/neu as a predictive marker of response to breast cancer therapy. Breast Cancer Res. Treat., 52: 65-77, 1998.
-
(1998)
Breast Cancer Res. Treat.
, vol.52
, pp. 65-77
-
-
Pegram, M.D.1
Pauletti, G.2
Slamon, D.J.3
-
10
-
-
0028142387
-
A specific inhibitor of the epidermal growth factor receptor tyrosine kinase
-
Fry, D. W., Kraker, A. J., McMichael, A., Ambroso, L. A., Nelson, J. M., Leopold, W. R., Connors, R. W., and Bridges, A. J. A specific inhibitor of the epidermal growth factor receptor tyrosine kinase. Science (Wash. DC), 265: 1093-1095, 1994.
-
(1994)
Science (Wash. DC)
, vol.265
, pp. 1093-1095
-
-
Fry, D.W.1
Kraker, A.J.2
McMichael, A.3
Ambroso, L.A.4
Nelson, J.M.5
Leopold, W.R.6
Connors, R.W.7
Bridges, A.J.8
-
11
-
-
0035168761
-
CI-1033, a pan-erbB tyrosine kinase inhibitor
-
Slichenmyer, W. J., Elliott, W. L., and Fry, D. W. CI-1033, a pan-erbB tyrosine kinase inhibitor. Semin. Oncol., 28: 80-85, 2001.
-
(2001)
Semin. Oncol.
, vol.28
, pp. 80-85
-
-
Slichenmyer, W.J.1
Elliott, W.L.2
Fry, D.W.3
-
12
-
-
0000299340
-
-
Vincent, P. W., Patmore, S. J., Atkinson, B. E., Bridges, A. J., Kirkish, L. S., and Dudeck, R. Proc. Am. Assoc. Cancer Res., 39: 117, 1999.
-
(1999)
Proc. Am. Assoc. Cancer Res.
, vol.39
, pp. 117
-
-
Vincent, P.W.1
Patmore, S.J.2
Atkinson, B.E.3
Bridges, A.J.4
Kirkish, L.S.5
Dudeck, R.6
-
13
-
-
0035170259
-
Anticancer therapy targeting the erbB family of receptor tyrosine kinases
-
Slichenmyer, W. J., and Fry, D. W. Anticancer therapy targeting the erbB family of receptor tyrosine kinases. Semin. Oncol., 28: 67-79, 2001.
-
(2001)
Semin. Oncol.
, vol.28
, pp. 67-79
-
-
Slichenmyer, W.J.1
Fry, D.W.2
-
14
-
-
0033304746
-
ErbB-2 overexpression in human mammary epithelial cells confers growth factor independence
-
Ignatoski, K. M., Lapointe, A. J., Radany, E. H., and Ethier, S. P. erbB-2 overexpression in human mammary epithelial cells confers growth factor independence. Endocrinology, 140: 3615-3622, 1999.
-
(1999)
Endocrinology
, vol.140
, pp. 3615-3622
-
-
Ignatoski, K.M.1
Lapointe, A.J.2
Radany, E.H.3
Ethier, S.P.4
-
15
-
-
0000446084
-
ERBB-2 overexpression confers P1 3′ kinase-dependent invasion capacity on human mammary epithelial cells
-
Ignatoski, K. M., Maehama, T., Markwart, S. M., Dixon, J. E., Livant, D. L., and Ethier, S. P. ERBB-2 overexpression confers P1 3′ kinase-dependent invasion capacity on human mammary epithelial cells. Br. J. Cancer, 82: 666-674, 2000.
-
(2000)
Br. J. Cancer
, vol.82
, pp. 666-674
-
-
Ignatoski, K.M.1
Maehama, T.2
Markwart, S.M.3
Dixon, J.E.4
Livant, D.L.5
Ethier, S.P.6
-
16
-
-
0030063936
-
Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients
-
Alo, P. L., Visca, P., Marci, A., Mangoni, A., Botti, C., and Di Tondo, U. Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients. Cancer (Phila.), 77: 474-482, 1996.
-
(1996)
Cancer (Phila.)
, vol.77
, pp. 474-482
-
-
Alo, P.L.1
Visca, P.2
Marci, A.3
Mangoni, A.4
Botti, C.5
Di Tondo, U.6
-
17
-
-
0028875706
-
OA-519 (fatty acid synthase) as an independent predictor of pathologic state in adenocarcinoma of the prostate
-
Epstein, J. I., Carmichael, M., and Partin, A. W. OA-519 (fatty acid synthase) as an independent predictor of pathologic state in adenocarcinoma of the prostate. Urology, 45: 81-86, 1995.
-
(1995)
Urology
, vol.45
, pp. 81-86
-
-
Epstein, J.I.1
Carmichael, M.2
Partin, A.W.3
-
18
-
-
0031007392
-
Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival
-
Gansler, T. S., Hardman, W., III, Hunt, D. A., Schaffel, S., and Hennigar, R. A. Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival. Hum. Pathol., 28: 686-692, 1997.
-
(1997)
Hum. Pathol.
, vol.28
, pp. 686-692
-
-
Gansler, T.S.1
Hardman, W.2
Hunt, D.A.3
Schaffel, S.4
Hennigar, R.A.5
-
19
-
-
0032147199
-
Fatty acid synthase expression in endometrial carcinoma: Correlation with cell proliferation and hormone receptors
-
Pizer, E. S., Lax, S. F., Kuhajda, F. P., Pasternack, G. R., and Kurman, R. J. Fatty acid synthase expression in endometrial carcinoma: correlation with cell proliferation and hormone receptors. Cancer (Phila.), 83: 528-537, 1998.
-
(1998)
Cancer (Phila.)
, vol.83
, pp. 528-537
-
-
Pizer, E.S.1
Lax, S.F.2
Kuhajda, F.P.3
Pasternack, G.R.4
Kurman, R.J.5
-
20
-
-
0033814153
-
Selective activation of the fatty acid synthesis pathway in human prostate cancer
-
Swinnen, J. V., Vanderhoydonc, F., Elgamal, A. A., Eelen, M., Vercaeren, I., Joniau, S., Van Poppel, H., Baert, L., Goossens, K., Heyns, W., and Verhoeven, G. Selective activation of the fatty acid synthesis pathway in human prostate cancer, Int. J. Cancer, 88: 176-179, 2000.
-
(2000)
Int. J. Cancer
, vol.88
, pp. 176-179
-
-
Swinnen, J.V.1
Vanderhoydonc, F.2
Elgamal, A.A.3
Eelen, M.4
Vercaeren, I.5
Joniau, S.6
Van Poppel, H.7
Baert, L.8
Goossens, K.9
Heyns, W.10
Verhoeven, G.11
-
21
-
-
0032532655
-
Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines
-
Pizer, E. S., Chrest, F. J., DiGiuseppe, J. A., and Han, W. F. Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines. Cancer Res., 58: 4611-4615, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4611-4615
-
-
Pizer, E.S.1
Chrest, F.J.2
DiGiuseppe, J.A.3
Han, W.F.4
-
22
-
-
0029949512
-
Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells
-
Pizer, E. S., Jackisch, C., Wood, F. D., Pasternack, G. R., Davidson, N. E., and Kuhajda, F. P. Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells. Cancer Res., 56: 2745-2747, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 2745-2747
-
-
Pizer, E.S.1
Jackisch, C.2
Wood, F.D.3
Pasternack, G.R.4
Davidson, N.E.5
Kuhajda, F.P.6
-
23
-
-
0037016729
-
Molecular cross-talk between the TRAIL and interferon signaling pathways
-
Kumar-Sinha, C., Varambally, S., Sreekumar, A., and Chinnaiyan, A. M. Molecular cross-talk between the TRAIL and interferon signaling pathways. J. Biol. Chem., 277: 575-585, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 575-585
-
-
Kumar-Sinha, C.1
Varambally, S.2
Sreekumar, A.3
Chinnaiyan, A.M.4
-
25
-
-
70449158340
-
A simple method for the isolation and purification of total lipids from animal tissues
-
Folch, J., Lees, M., and Stanley, G. H. S. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem., 226: 497-509, 1956.
-
(1956)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Stanley, G.H.S.3
-
26
-
-
0030666828
-
Coordinate regulation of lipogenic gene expression by androgens: Evidence for a cascade mechanism involving sterol regulatory element binding proteins
-
Swinnen, J. V., Ulrix, W., Heyns, W., and Verhoeven, G. Coordinate regulation of lipogenic gene expression by androgens: evidence for a cascade mechanism involving sterol regulatory element binding proteins. Proc. Natl. Acad. Sci. USA, 94: 12975-12980, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12975-12980
-
-
Swinnen, J.V.1
Ulrix, W.2
Heyns, W.3
Verhoeven, G.4
-
27
-
-
0035939903
-
Delineation of prognostic biomarkers in prostate cancer
-
Dhanasekaran, S. M., Barrette, T. R., Ghosh, D., Shah, R., Varambally, S., Kurachi, K., Pienta, K. J., Rubin, M. A., and Chinnaiyan, A. M. Delineation of prognostic biomarkers in prostate cancer. Nature (Lond.), 412: 822-826, 2001.
-
(2001)
Nature (Lond.)
, vol.412
, pp. 822-826
-
-
Dhanasekaran, S.M.1
Barrette, T.R.2
Ghosh, D.3
Shah, R.4
Varambally, S.5
Kurachi, K.6
Pienta, K.J.7
Rubin, M.A.8
Chinnaiyan, A.M.9
-
28
-
-
0034791515
-
Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway
-
Heemers, H., Maes, B., Foufelle, F., Heyns, W., Verhoeven, G., and Swinnen, J. V. Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway. Mol. Endocrinol., 15: 1817-1828, 2001.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1817-1828
-
-
Heemers, H.1
Maes, B.2
Foufelle, F.3
Heyns, W.4
Verhoeven, G.5
Swinnen, J.V.6
-
29
-
-
0037724456
-
-
American Cancer Society, Atlanta, GA
-
American Cancer Society. Cancer Fact and Figures 2002. American Cancer Society, Atlanta, GA, 2002.
-
(2002)
Cancer Fact and Figures 2002
-
-
-
30
-
-
0027494344
-
Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer
-
Arason, A., Barkardottir, R. B., and Egilsson, V. Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer. Am. J. Hum. Genet., 52: 711-717, 1993.
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 711-717
-
-
Arason, A.1
Barkardottir, R.B.2
Egilsson, V.3
-
31
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki, Y., Swensen, J., Shattuck-Eidens, D., Futreal, P. A., Harshman, K., Tavtigian, S., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science (Wash. DC), 266: 66-71, 1994.
-
(1994)
Science (Wash. DC)
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
Liu, Q.7
Cochran, C.8
Bennett, L.M.9
Ding, W.10
-
32
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRC42
-
Wooster, R., Bignell, G., Lancaster, J., Swift, S., Seal, S., Mangion, J., Collins, N., Gregory, S., Gumbs, C., and Micklem, G. Identification of the breast cancer susceptibility gene BRC42. Nature (Lond.). 378: 789-792, 1995.
-
(1995)
Nature (Lond.)
, vol.378
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
Swift, S.4
Seal, S.5
Mangion, J.6
Collins, N.7
Gregory, S.8
Gumbs, C.9
Micklem, G.10
-
33
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou, C. M., Sorlie, T., Eisen, M. B., van de Rijn, M., Jeffrey, S. S., Rees, C. A., Pollack, J. R., Ross, D. T., Johnsen, H., Akslen, L. A., Fluge, O., Pergamenschikov, A., Williams, C., Zhu, S. X., Lonning, P. E., Borresen-Dale, A. L., Brown, P. O., and Botstein, D. Molecular portraits of human breast tumours. Nature (Lond.), 406: 747-752, 2000.
-
(2000)
Nature (Lond.)
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
Van de Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
Pollack, J.R.7
Ross, D.T.8
Johnsen, H.9
Akslen, L.A.10
Fluge, O.11
Pergamenschikov, A.12
Williams, C.13
Zhu, S.X.14
Lonning, P.E.15
Borresen-Dale, A.L.16
Brown, P.O.17
Botstein, D.18
-
34
-
-
0034601455
-
Molecular classification of cutaneous malignant melanoma by gene expression profiling
-
Bittner, M., Meltzer, P., Chen, Y., Jiang, Y., Seftor, E., Hendrix, M., Radmacher, M., Simon, R., Yakhini, Z., Ben-Dor, A., Sampas, N., Dougherty, E., Wang, E., Marincola, F., Gooden, C., Lueders, J., Glatfelter, A., Pollock, P., Carpten, J., Gillanders, E., Leja, D., Dietrich, K., Beaudry, C., Berens, M., Alberts, D., and Sondak, V. Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature (Lond.), 406: 536-540, 2000.
-
(2000)
Nature (Lond.)
, vol.406
, pp. 536-540
-
-
Bittner, M.1
Meltzer, P.2
Chen, Y.3
Jiang, Y.4
Seftor, E.5
Hendrix, M.6
Radmacher, M.7
Simon, R.8
Yakhini, Z.9
Ben-Dor, A.10
Sampas, N.11
Dougherty, E.12
Wang, E.13
Marincola, F.14
Gooden, C.15
Lueders, J.16
Glatfelter, A.17
Pollock, P.18
Carpten, J.19
Gillanders, E.20
Leja, D.21
Dietrich, K.22
Beaudry, C.23
Berens, M.24
Alberts, D.25
Sondak, V.26
more..
-
35
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie, T., Perou, C. M., Tibshirani, R., Aas, T., Geisler, S., Johnsen, H., Hastie, T., Eisen, M. B., van de Rijn, M., Jeffrey, S. S., Thorsen, T., Quist, H., Matese, J. C., Brown, P. O., Botstein, D., Eystein Lonning, P., and Borresen-Dale, A. L. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. USA, 98: 10869-10874, 2001.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
Van de Rijn, M.9
Jeffrey, S.S.10
Thorsen, T.11
Quist, H.12
Matese, J.C.13
Brown, P.O.14
Botstein, D.15
Eystein Lonning, P.16
Borresen-Dale, A.L.17
-
36
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer, L. J., Dai, H., van de Vijver, M. J., He, Y. D., Hart, A. A., Mao, M., Peterse, H. L., van der Kooy, K., Marton, M. J., Witteveen, A. T., Schreiber, G. J., Kerkhoven, R. M., Roberts, C., Linsley, P. S., Bernards, R., and Friend, S. H. Gene expression profiling predicts clinical outcome of breast cancer. Nature (Lond.), 415: 530-536, 2002.
-
(2002)
Nature (Lond.)
, vol.415
, pp. 530-536
-
-
Van't Veer, L.J.1
Dai, H.2
Van de Vijver, M.J.3
He, Y.D.4
Hart, A.A.5
Mao, M.6
Peterse, H.L.7
Van der Kooy, K.8
Marton, M.J.9
Witteveen, A.T.10
Schreiber, G.J.11
Kerkhoven, R.M.12
Roberts, C.13
Linsley, P.S.14
Bernards, R.15
Friend, S.H.16
-
37
-
-
0035931947
-
Gene-expression profiles in hereditary breast cancer
-
Hedenfalk, I., Duggan, D. D., Chen, Y., Radmacher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B. A., Esteller, M., Kallioniemi, O. P., Wilfond, B., Borg, A., and Trent, J. Gene-expression profiles in hereditary breast cancer. N. Engl. J. Med., 344: 539-548, 2001.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 539-548
-
-
Hedenfalk, I.1
Duggan, D.D.2
Chen, Y.3
Radmacher, M.4
Bittner, M.5
Simon, R.6
Meltzer, P.7
Gusterson, B.A.8
Esteller, M.9
Kallioniemi, O.P.10
Wilfond, B.11
Borg, A.12
Trent, J.13
-
38
-
-
0034050902
-
Systematic variation in gene expression patterns in human cancer cell lines
-
Ross, D. T., Scherf, U., Eisen, M. B., Perou, C. M., Rees, C., Spellman, P., Iyer, V., Jeffrey, S. S., Van de Rijn, M., Waltham, M., Pergamenschikov, A., Lee, J. C., Lashkari, D., Shalon, D., Myers, T. G., Weinstein, J. N., Botstein, D., and Brown, P. O. Systematic variation in gene expression patterns in human cancer cell lines. Nat. Genet., 24: 227-235, 2000.
-
(2000)
Nat. Genet.
, vol.24
, pp. 227-235
-
-
Ross, D.T.1
Scherf, U.2
Eisen, M.B.3
Perou, C.M.4
Rees, C.5
Spellman, P.6
Iyer, V.7
Jeffrey, S.S.8
Van de Rijn, M.9
Waltham, M.10
Pergamenschikov, A.11
Lee, J.C.12
Lashkari, D.13
Shalon, D.14
Myers, T.G.15
Weinstein, J.N.16
Botstein, D.17
Brown, P.O.18
-
39
-
-
0033557839
-
Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays
-
Bubendorf, L., Kononen, J., Koivisto, P., Schraml, P., Moch, H., Gasser, T. C., Willi, N., Mihatsch, M. J., Sauter, G., and Kallioniemi, O. P. Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays. Cancer Res., 59: 803-806, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 803-806
-
-
Bubendorf, L.1
Kononen, J.2
Koivisto, P.3
Schraml, P.4
Moch, H.5
Gasser, T.C.6
Willi, N.7
Mihatsch, M.J.8
Sauter, G.9
Kallioniemi, O.P.10
-
40
-
-
0035097430
-
Profiling and verification of gene expression patterns in normal and malignant human prostate tissues by cDNA microarray analysis
-
Chaib, H., Cockrell, E. K., Rubin, M. A., and Macoska, J. A. Profiling and verification of gene expression patterns in normal and malignant human prostate tissues by cDNA microarray analysis. Neoplasia, 3: 43-52, 2001.
-
(2001)
Neoplasia
, vol.3
, pp. 43-52
-
-
Chaib, H.1
Cockrell, E.K.2
Rubin, M.A.3
Macoska, J.A.4
-
41
-
-
0345240919
-
Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: A revelation by parallel gene expression profiling
-
Fuller, G. N., Rhee, C. H., Hess, K. R., Caskey, L. S., Wang, R., Bruner, J. M., Yung, W. K., and Zhang, W. Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling. Cancer Res., 59: 4228-4232, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 4228-4232
-
-
Fuller, G.N.1
Rhee, C.H.2
Hess, K.R.3
Caskey, L.S.4
Wang, R.5
Bruner, J.M.6
Yung, W.K.7
Zhang, W.8
-
42
-
-
0033862982
-
Grading of diffusely infiltrating astrocytomas by quantitative histopathology, cell proliferation and image cytometric DNA analysis. Comparison of 133 tumours in the context of the WHO 1979 and WHO 1993 grading schemes
-
Sallinen, P. K., Sallinen, S. L., Helen, P. T., Rantala, I. S., Rautiainen, E., Helin, H. J., Kalimo, H., and Haapasalo, H. K. Grading of diffusely infiltrating astrocytomas by quantitative histopathology, cell proliferation and image cytometric DNA analysis. Comparison of 133 tumours in the context of the WHO 1979 and WHO 1993 grading schemes. Neuropathol. Appl. Neurobiol., 26: 319-331, 2000.
-
(2000)
Neuropathol. Appl. Neurobiol.
, vol.26
, pp. 319-331
-
-
Sallinen, P.K.1
Sallinen, S.L.2
Helen, P.T.3
Rantala, I.S.4
Rautiainen, E.5
Helin, H.J.6
Kalimo, H.7
Haapasalo, H.K.8
-
43
-
-
0029929513
-
Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine-phosphorylated p185erbB-2
-
Ram, T. G., Dilts, C. A., Dziubinski, M. L., Pierce, L. J., and Ethier, S. P. Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine-phosphorylated p185erbB-2. Mol. Carcinog., 15: 227-238, 1996.
-
(1996)
Mol. Carcinog.
, vol.15
, pp. 227-238
-
-
Ram, T.G.1
Dilts, C.A.2
Dziubinski, M.L.3
Pierce, L.J.4
Ethier, S.P.5
-
44
-
-
0029824114
-
Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification
-
Ram, T. G., and Ethier, S. P. Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification. Cell Growth Differ., 7: 551-561, 1996.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 551-561
-
-
Ram, T.G.1
Ethier, S.P.2
-
45
-
-
0034091963
-
Heregulin-β is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells
-
Ram, T. G., Hosick, H. L., and Ethier, S. P. Heregulin-β is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells. J. Cell Physiol., 183: 301-313, 2000.
-
(2000)
J. Cell Physiol.
, vol.183
, pp. 301-313
-
-
Ram, T.G.1
Hosick, H.L.2
Ethier, S.P.3
-
46
-
-
0032939619
-
Rho GTPases are over-expressed in human tumors
-
Fritz, G., Just, I., and Kaina, B. Rho GTPases are over-expressed in human tumors. Int. J. Cancer, 81: 682-687, 1999.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 682-687
-
-
Fritz, G.1
Just, I.2
Kaina, B.3
-
47
-
-
0031685364
-
Cysteine proteinases and their endogenous inhibitors: Target proteins for prognosis, diagnosis and therapy in cancer
-
Kos, J., and Lah, T. T. Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer. Oncol Rep., 5: 1349-1361, 1998.
-
(1998)
Oncol Rep.
, vol.5
, pp. 1349-1361
-
-
Kos, J.1
Lah, T.T.2
-
48
-
-
0030850748
-
Specific regulation of HSPs in human tumor cell lines by flavonoids
-
Morino, M., Tsuzuki, T., Ishikawa, Y., Shirakami, T., Yoshimura, M., Kiyosuke, Y., Matsunaga, K., Yoshikumi, C., and Saijo, N. Specific regulation of HSPs in human tumor cell lines by flavonoids. In Vivo, 11: 265-270, 1997.
-
(1997)
In Vivo
, vol.11
, pp. 265-270
-
-
Morino, M.1
Tsuzuki, T.2
Ishikawa, Y.3
Shirakami, T.4
Yoshimura, M.5
Kiyosuke, Y.6
Matsunaga, K.7
Yoshikumi, C.8
Saijo, N.9
-
49
-
-
0033197879
-
SLUG a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
-
Inukai, T., Inoue, A., Kurosawa, H., Goi, K., Shinjyo, T., Ozawa, K., Mao, M., Inaba, T., and Look, A. T. SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol. Cell, 4: 343-352, 1999.
-
(1999)
Mol. Cell
, vol.4
, pp. 343-352
-
-
Inukai, T.1
Inoue, A.2
Kurosawa, H.3
Goi, K.4
Shinjyo, T.5
Ozawa, K.6
Mao, M.7
Inaba, T.8
Look, A.T.9
-
50
-
-
0035866376
-
Down-regulation of promoter 1.3 activity of the human aromatase gene in breast tissue by zinc-finger protein, snail (SnaH)
-
Okubo, T., Truong, T. K., Yu, B., Itoh, T., Zhao, J., Grube, B., Zhou, D., and Chen, S. Down-regulation of promoter 1.3 activity of the human aromatase gene in breast tissue by zinc-finger protein, snail (SnaH). Cancer Res., 61: 1338-1346, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 1338-1346
-
-
Okubo, T.1
Truong, T.K.2
Yu, B.3
Itoh, T.4
Zhao, J.5
Grube, B.6
Zhou, D.7
Chen, S.8
-
51
-
-
0029931625
-
Transcriptional regulation of the human biglycan gene
-
Ungefroren, H., and Krull, N. B. Transcriptional regulation of the human biglycan gene. J. Biol. Chem., 271: 15787-15795, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15787-15795
-
-
Ungefroren, H.1
Krull, N.B.2
-
52
-
-
0029819947
-
Co-ordinate induction of collagen type 1 and biglycan expression in keloids
-
Hunzelmann, N., Anders, S., Sollberg, S., Schonherr, E., and Krieg, T. Co-ordinate induction of collagen type 1 and biglycan expression in keloids. Br. J. Dermatol., 135: 394-399, 1996.
-
(1996)
Br. J. Dermatol.
, vol.135
, pp. 394-399
-
-
Hunzelmann, N.1
Anders, S.2
Sollberg, S.3
Schonherr, E.4
Krieg, T.5
-
54
-
-
0035866378
-
Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53
-
Li, X. N., Gorospe, M., Chrest, F. I., Kumaravel, T. S., Evans, M. K., Han, W. F., and Pizer, E. S. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer Res., 61: 1493-1499, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 1493-1499
-
-
Li, X.N.1
Gorospe, M.2
Chrest, F.I.3
Kumaravel, T.S.4
Evans, M.K.5
Han, W.F.6
Pizer, E.S.7
-
55
-
-
0034806134
-
Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity
-
Thupari, J. N., Pinn, M. L., and Kuhajda, F. P. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. Biochem. Biophys. Res. Commun., 285: 217-223, 2001.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.285
, pp. 217-223
-
-
Thupari, J.N.1
Pinn, M.L.2
Kuhajda, F.P.3
-
56
-
-
0034650757
-
Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts
-
Pizer, E. S., Thupari, J., Han, W. F., Pinn, M. L., Chrest, F. J., Frehywot, G. L., Townsend, C. A., and Kuhajda, F. P. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. Cancer Res., 60: 213-218, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 213-218
-
-
Pizer, E.S.1
Thupari, J.2
Han, W.F.3
Pinn, M.L.4
Chrest, F.J.5
Frehywot, G.L.6
Townsend, C.A.7
Kuhajda, F.P.8
-
57
-
-
0036497907
-
Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer
-
Swinnen, J. V., Roskams, T., Joniau, S., Van Poppel, H., Oyen, R., Baert, L., Heyns, W., and Verhoeven, G. Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer. Int. J. Cancer, 98: 19-22, 2002.
-
(2002)
Int. J. Cancer
, vol.98
, pp. 19-22
-
-
Swinnen, J.V.1
Roskams, T.2
Joniau, S.3
Van Poppel, H.4
Oyen, R.5
Baert, L.6
Heyns, W.7
Verhoeven, G.8
-
58
-
-
0030706079
-
Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
-
Milgraum, L. Z., Witters, L. A., Pasternack, G. R., and Kuhajda, F. P. Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma. Clin. Cancer Res., 3: 2115-2120, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 2115-2120
-
-
Milgraum, L.Z.1
Witters, L.A.2
Pasternack, G.R.3
Kuhajda, F.P.4
-
59
-
-
0034718771
-
Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
-
Swinnen, J. V., Heemers, H., Deboel, L., Foufelle, F., Heyns, W., and Verhoeven, G. Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway. Oncogene, 19: 5173-5181, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 5173-5181
-
-
Swinnen, J.V.1
Heemers, H.2
Deboel, L.3
Foufelle, F.4
Heyns, W.5
Verhoeven, G.6
-
60
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown, M. S., and Goldstein, J. L. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell, 89: 331-340, 1997.
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
61
-
-
0031963963
-
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1
-
Kim, J. B., Sarraf, P., Wright, M., Yao, K. M., Mueller, E., Solanes, G., Lowell, B. B., and Spiegelman, B. M. Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J. Clin. Investig., 101: 1-9, 1998.
-
(1998)
J. Clin. Investig.
, vol.101
, pp. 1-9
-
-
Kim, J.B.1
Sarraf, P.2
Wright, M.3
Yao, K.M.4
Mueller, E.5
Solanes, G.6
Lowell, B.B.7
Spiegelman, B.M.8
-
62
-
-
0343851602
-
Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade
-
Kotzka, J., Muller-Wieland, D., Roth, G., Kremer, L., Munck, M., Schurmann, S., Knebel, B., and Krone, W. Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade. J. Lipid Res., 41: 99-108, 2000.
-
(2000)
J. Lipid Res.
, vol.41
, pp. 99-108
-
-
Kotzka, J.1
Muller-Wieland, D.2
Roth, G.3
Kremer, L.4
Munck, M.5
Schurmann, S.6
Knebel, B.7
Krone, W.8
-
63
-
-
0034235363
-
Regulation of sterol regulatory-element binding protein 1 gene expression in liver: Role of insulin and protein kinase B/cAkt
-
Fleischmann, M., and Iynedjian, P. B. Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt. Biochem. J., 349: 13-17, 2000.
-
(2000)
Biochem. J.
, vol.349
, pp. 13-17
-
-
Fleischmann, M.1
Iynedjian, P.B.2
-
64
-
-
0036385719
-
Activation of fatty acid synthesis during neoplastic transformation: Role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
-
Yang, Y., Han, W., Morin, P., Chrest, F., and Pizer, E. Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Exp. Cell Res., 279: 80-90, 2002.
-
(2002)
Exp. Cell Res.
, vol.279
, pp. 80-90
-
-
Yang, Y.1
Han, W.2
Morin, P.3
Chrest, F.4
Pizer, E.5
|