Human prostate cancer cells lack feedback regulation of low-density lipoprotein receptor and its regulator, SREBP2

International Journal of Cancer

Volumn 91, Issue 1, 2001, Pages 41-45

  Chen, Yunfei ^a   Hughes Fulford, Millie ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Feedback regulation; LDL receptor; PGE2; Prostate cancer; SREBP2

Indexed keywords

CHOLESTEROL; ESSENTIAL FATTY ACID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; PROSTAGLANDIN E2; STEROL REGULATORY ELEMENT BINDING PROTEIN;

ARTICLE; CANCER CELL; CELL GROWTH; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; FATTY ACID SYNTHESIS; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROSTATE CANCER; PROTEIN EXPRESSION;

NON-PROGRAMMATIC;

CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CHOLESTEROL; DINOPROSTONE; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDOCYTOSIS; HUMANS; LIPOPROTEINS, LDL; MALE; PROMOTER REGIONS (GENETICS); PROSTATE; PROSTATIC NEOPLASMS; RECEPTORS, LDL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0035195361     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(20010101)91:1<41::AID-IJC1009>3.0.CO;2-2     Document Type: Article

References (28)

1. A receptor-mediated pathway for cholesterol homeostasis
2. The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA
3. Regulation of the activity of the low density lipoprotein receptor in human fibroblasts
4. Differences between the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and low density lipoprotein receptor in human hepatoma cells and fibroblasts reside primarily at the translational and post-translational levels
5. Regulation of low density lipoprotein receptor activity in freshly isolated human lymphocytes
6. Regulation of low-density lipoprotein receptors and assessment of their functional role in Burkitt's lymphoma cells
7. Regulation of low density lipoprotein receptor activity in primary cultures of human hepatocytes by serum lipoproteins
8. Concerted regulation of low density lipoprotein receptor gene expression by follicle-stimulating hormone and insulin-like growth factor I in porcine granulosa cells: Promoter activation, messenger ribonucleic acid stability, and sterol feedback
9. Evidence for up-regulated low density lipoprotein receptor in human lung adenocarcinoma cell line A549
10. Coordinate up-regulation of low-density lipoprotein receptor and cyclooxygenase-2 gene expression in human colorectal cells and in colorectal adenocarcinoma biopsies
11. Decreased feedback regulation of low density lipoprotein receptor activity by sterols in leukemic cells from patients with acute myelogenous leukemia
12. Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene
13. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
14. The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor
15. Role of thymus-eicosanoids in the immune response
16. Aspirin and the potential role of prostaglandins in colon cancer
17. Human alveolar macrophages suppress interleukin-1 (IL-1) activity via the secretion of prostaglandin E2
18. Induction of cyclooxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells
19. Quantitative PCR: A survey of the present technology
20. Establishment and characterization of an immortalized but nontransformed human prostate epithelial cell line: BPH-1
21. Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells
22. Regulation of the mevalonate pathway
23. Regulation of cholesterol synthesis in normal and malignant tissue
24. Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2)
25. 4-octadecyl-1-β-D-arabinofuranosylcytosine in Daudi lymphoma cells
26. Dietary fatty acids and cancer
27. Effects of fatty acids and eicosanoid synthesis inhibitors on the growth of two human prostate cancer cell lines
28. Effects of dietary fatty acids on DU145 human prostate cancer cell growth in athymic nude mice