Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells

Oncogene

Volumn 24, Issue 22, 2005, Pages 3574-3582

  Wang, Hui Qin ^a   Altomare, Deborah A ^a   Skele, Kristine L ^a   Poulikakos, Poulikos I ^a   Kuhajda, Francis P ^b   Di Cristofano, Antonio ^a   Testa, Joseph R ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AKT protein kinase B; Apoptosis; Fatty acid synthase; Ovarian cancer

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 IMIDAZOLECARBOXYLIC ACID ETHYL ESTER; C 75; CERULENIN; FATTY ACID SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OVARY CARCINOMA; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCID MOUSE; TISSUE MICROARRAY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 4-BUTYROLACTONE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; ENZYME ACTIVATION; ENZYME INHIBITORS; FATTY ACID SYNTHETASE COMPLEX; FEEDBACK, BIOCHEMICAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; OVARIAN NEOPLASMS; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEINS;

EID: 19944374798     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208463     Document Type: Article

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