Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1

Cancer Research

Volumn 68, Issue 4, 2008, Pages 1003-1011

  Furuta, Eiji ^a   Pai, Sudha K ^a   Zhan, Rui ^a   Bandyopadhyay, Sucharita ^b   Watabe, Misako ^a   Mo, Yin Yuan ^a   Hirota, Shigeru ^c   Hosobe, Sadahiro ^c   Tsukada, Taisei ^c   Miura, Kunio ^c   Kamada, Shuichi ^c   Saito, Ken ^c   Iiizumi, Megumi ^a   Liu, Wen ^a   Ericsson, Johan ^d   Watabe, Kounosuke ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c AKITA RED CROSS HOSPITAL   (Japan)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CERULENIN; CYCLOPHOSPHAMIDE; FATTY ACID SYNTHASE; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; E BOX ELEMENT; ENZYME ACTIVATION; ENZYME ASSAY; FATTY ACID SYNTHASE GENE; FEMALE; GENE; GENE CONTROL; GENETIC REGULATION; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; CYCLOPHOSPHAMIDE; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; ENZYME INHIBITORS; FATTY ACID SYNTHETASE COMPLEX; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MICE; MICE, NUDE; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UP-REGULATION;

EID: 39549117982     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-2489     Document Type: Article

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