C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase

Journal of Biological Chemistry

Volumn 279, Issue 19, 2004, Pages 19970-19976

  Kim, Eun Kyoung ^a   Miller, Ian ^a   Aja, Susan ^a   Landree, Leslie E ^a   Pinn, Michael ^a   McFadden, Jill ^b   Kuhajda, Francis P ^a   Moran, Timothy H ^a   Ronnett, Gabriele V ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FASgen Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CHEMICAL ACTIVATION; ENZYME INHIBITION; ENZYMES; FATTY ACIDS; NEUROLOGY; PHYSIOLOGY; SENSORS;

HYPOTHALAMUS; NEURONS; PHOSPHORYLATION;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATE; C 75; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENZYME INHIBITOR; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NEUROPEPTIDE Y; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANOREXIA; ARCUATE NUCLEUS; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIET RESTRICTION; ENERGY BALANCE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEEDING; FOOD INTAKE; HYPOTHALAMUS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WEIGHT REDUCTION;

4-BUTYROLACTONE; ADENOSINE TRIPHOSPHATE; AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; ANOREXIA; ARCUATE NUCLEUS; BLOTTING, NORTHERN; BLOTTING, WESTERN; EATING; FATTY ACID SYNTHETASE COMPLEX; FEEDING BEHAVIOR; HYPOTHALAMUS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED BALB C; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RIBONUCLEOTIDES; RNA; TIME FACTORS;

ANIMALIA;

EID: 2442631468     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402165200     Document Type: Article

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