-
1
-
-
0030134246
-
Immunological tolerance: Danger - Pathogen on the premises!
-
CA Janeway, Jr., CC Goodnow, and R Medzhitov: Danger - pathogen on the premises! Immunological tolerance. Curr. Biol. 6, 519-522 (1996). (Pubitemid 126656302)
-
(1996)
Current Biology
, vol.6
, Issue.5
, pp. 519-522
-
-
Janeway Jr., C.A.1
Goodnow, C.C.2
Medzhitov, R.3
-
2
-
-
0030666222
-
Innate immunity: The virtues of a nonclonal system of recognition
-
DOI 10.1016/S0092-8674(00)80412-2
-
R Medzhitov, and CA Janeway: Innate immunity: the virtues of a nonclonal system of recognition. Cell 91, 295- 298 (1997). (Pubitemid 27467959)
-
(1997)
Cell
, vol.91
, Issue.3
, pp. 295-298
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
3
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
H Kumar, T Kawai, and S Akira: Pathogen recognition by the innate immune system. Int. Rev. Immunol. 30, 16-34 (2011).
-
(2011)
Int. Rev. Immunol.
, vol.30
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
4
-
-
66949122854
-
Approaching the asymptote: 20 years later
-
R Medzhitov: Approaching the asymptote: 20 years later. Immunity. 30, 766-775 (2009).
-
(2009)
Immunity
, vol.30
, pp. 766-775
-
-
Medzhitov, R.1
-
5
-
-
33745847180
-
TLRs, NLRs and RLRs: A trinity of pathogen sensors that co-operate in innate immunity
-
DOI 10.1016/j.it.2006.06.003, PII S1471490606001724
-
EM Creagh, and LA O'Neill: TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity. Trends Immunol. 27, 352-357 (2006). (Pubitemid 44038661)
-
(2006)
Trends in Immunology
, vol.27
, Issue.8
, pp. 352-357
-
-
Creagh, E.M.1
O'Neill, L.A.J.2
-
7
-
-
75649106430
-
Intracellular DNA recognition
-
V Hornung, and E Latz: Intracellular DNA recognition. Nat Rev. Immunol. 10, 123-130 (2010).
-
(2010)
Nat Rev. Immunol.
, vol.10
, pp. 123-130
-
-
Hornung, V.1
Latz, E.2
-
8
-
-
46749136412
-
When signaling pathways collide: Positive and negative regulation of toll-like receptor signal transduction
-
LA O'Neill: When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction. Immunity 29, 12-20 (2008).
-
(2008)
Immunity
, vol.29
, pp. 12-20
-
-
O'neill, L.A.1
-
9
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signalling
-
DOI 10.1038/43206
-
R Starr, TA Willson, EM Viney, LJ Murray, JR Rayner, BJ Jenkins, TJ Gonda, WS Alexander, D Metcalf, NA Nicola, and DJ Hilton: A family of cytokine-inducible inhibitors of signalling. Nature 387, 917-921 (1997). (Pubitemid 27289594)
-
(1997)
Nature
, vol.387
, Issue.6636
, pp. 917-921
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
Murray, L.J.L.4
Rayner, J.R.5
Jenkins, B.J.6
Gonda, T.J.7
Alexander, W.S.8
Metcalf, D.9
Nicola, N.A.10
Hilton, D.J.11
-
10
-
-
0030839112
-
A new protein containing an SH2 domain that inhibits JAK kinases
-
DOI 10.1038/43213
-
TA Endo, M Masuhara, M Yokouchi, R Suzuki, H Sakamoto, K Mitsui, A Matsumoto, S Tanimura, M Ohtsubo, H Misawa, T Miyazaki, N Leonor, T Taniguchi, T Fujita, Y Kanakura, S Komiya, and A Yoshimura: A new protein containing an SH2 domain that inhibits JAK kinases. Nature 387, 921-924 (1997). (Pubitemid 27289595)
-
(1997)
Nature
, vol.387
, Issue.6636
, pp. 921-924
-
-
Endo, T.A.1
Masuhara, M.2
Yokouchi, M.3
Suzuki, R.4
Sakamoto, H.5
Mitsui, K.6
Matsumoto, A.7
Tanimura, S.8
Ohtsubo, M.9
Misawa, H.10
Miyazaki, T.11
Leonor, N.12
Taniguchi, T.13
Fujita, T.14
Kanakura, Y.15
Komiya, S.16
Yoshimura, A.17
-
11
-
-
0030755934
-
Structure and function of a new STAT-induced STAT inhibitor
-
DOI 10.1038/43219
-
T Naka, M Narazaki, M Hirata, T Matsumoto, S Minamoto, A Aono, N Nishimoto, T Kajita, T Taga, K Yoshizaki, S Akira, and T Kishimoto: Structure and function of a new STAT-induced STAT inhibitor. Nature 387, 924-929 (1997). (Pubitemid 27289596)
-
(1997)
Nature
, vol.387
, Issue.6636
, pp. 924-929
-
-
Naka, T.1
Narazaki, M.2
Hirata, M.3
Matsumoto, T.4
Minamoto, S.5
Aono, A.6
Nishimoto, N.7
Kajita, T.8
Taga, T.9
Yoshizaki, K.10
Akira, S.11
Kishimoto, T.12
-
12
-
-
0029014206
-
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoetin receptors
-
A Yoshimura, T Ohkubo, T Kiguchi, NA Jenkins, DJ Gilbert, NG Copeland, T Hara, and A Miyajima: A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoetin receptors. EMBO J. 14, 2816-2826 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 2816-2826
-
-
Yoshimura, A.1
Ohkubo, T.2
Kiguchi, T.3
Jenkins, N.A.4
Gilbert, D.J.5
Copeland, N.G.6
Hara, T.7
Miyajima, A.8
-
13
-
-
34249660614
-
SOCS proteins, cytokine signalling and immune regulation
-
DOI 10.1038/nri2093, PII NRI2093
-
A Yoshimura, T Naka, and M Kubo: SOCS proteins, cytokine signalling and immune regulation. Nat Rev. Immunol. 7, 454-465 (2007). (Pubitemid 46834848)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.6
, pp. 454-465
-
-
Yoshimura, A.1
Naka, T.2
Kubo, M.3
-
14
-
-
0033197958
-
Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-γ
-
D Stoiber, P Kovarik, S Cohney, JA Johnston, P Steinlein, and T Decker: Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma. J. Immunol. 163, 2640- 2647 (1999). (Pubitemid 29399188)
-
(1999)
Journal of Immunology
, vol.163
, Issue.5
, pp. 2640-2647
-
-
Stoiber, D.1
Kovarik, P.2
Cohney, S.3
Johnston, J.A.4
Steinlein, P.5
Decker, T.6
-
15
-
-
0035877256
-
1
-
AH Dalpke, S Opper, S Zimmermann, and K Heeg: Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs. J. Immunol. 166, 7082-7089 (2001). (Pubitemid 32525577)
-
(2001)
Journal of Immunology
, vol.166
, Issue.12
, pp. 7082-7089
-
-
Dalpke, A.H.1
Opper, S.2
Zimmermann, S.3
Heeg, K.4
-
16
-
-
0033233214
-
LPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages
-
DOI 10.1016/S0014-5793(99)01662-2, PII S0014579399016622
-
JG Bode, A Nimmesgern, J Schmitz, F Schaper, M Schmitt, W Frisch, D Haussinger, PC Heinrich, and L Graeve: LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett. 463, 365-370 (1999). (Pubitemid 30001952)
-
(1999)
FEBS Letters
, vol.463
, Issue.3
, pp. 365-370
-
-
Bode, J.G.1
Nimmesgern, A.2
Schmitz, J.3
Schaper, F.4
Schmitt, M.5
Frisch, W.6
Haussinger, D.7
Heinrich, P.C.8
Graeve, L.9
-
17
-
-
41649109532
-
Suppressor of cytokine signaling (SOCS) proteins in innate immunity
-
Vol. 6, S. G. Pandalai, ed. Recent Res Develop. Immunology, Research Signpost, Trivandrum
-
Dalpke, A. H. 2004. Suppressor of cytokine signaling (SOCS) proteins in innate immunity. In Recent Res Develop. Immunology. Vol. 6, Vol. 6. S. G. Pandalai, ed. Recent Res Develop. Immunology, Research Signpost, Trivandrum, pp. 317-339.
-
(2004)
Recent Res Develop. Immunology
, vol.6
, pp. 317-339
-
-
Dalpke, A.H.1
-
18
-
-
0033305487
-
Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo
-
Y Mao, PR Ling, TP Fitzgibbons, KC McCowen, GP Frick, BR Bistrian, and RJ Smith: Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo. Endocrinology 140, 5505-5515 (1999). (Pubitemid 30645337)
-
(1999)
Endocrinology
, vol.140
, Issue.12
, pp. 5505-5515
-
-
Mao, Y.1
Ling, P.-R.2
Fitzgibbons, T.P.3
McCowen, K.C.4
Frick, G.P.5
Bistrian, B.R.6
Smith, R.J.7
-
19
-
-
18744371050
-
SOCS-1 participates in negative regulation of LPS responses
-
DOI 10.1016/S1074-7613(02)00449-1
-
R Nakagawa, T Naka, H Tsutsui, M Fujimoto, A Kimura, T Abe, E Seki, S Sato, O Takeuchi, K Takeda, S Akira, K Yamanishi, I Kawase, K Nakanishi, and T Kishimoto: SOCS-1 participates in negative regulation of LPS responses. Immunity 17, 677-687 (2002). (Pubitemid 35351512)
-
(2002)
Immunity
, vol.17
, Issue.5
, pp. 677-687
-
-
Nakagawa, R.1
Naka, T.2
Tsutsui, H.3
Fujimoto, M.4
Kimura, A.5
Abe, T.6
Seki, E.7
Sato, S.8
Takeuchi, O.9
Takeda, K.10
Akira, S.11
Yamanishi, K.12
Kawase, I.13
Nakanishi, K.14
Kishimoto, T.15
-
20
-
-
0036850946
-
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation
-
DOI 10.1016/S1074-7613(02)00446-6
-
I Kinjyo, T Hanada, K Inagaki-Ohara, H Mori, D Aki, M Ohishi, H Yoshida, M Kubo, and A Yoshimura: SOCS1/JAB Is a Negative Regulator of LPS-Induced Macrophage Activation. Immunity 17, 583-591 (2002). (Pubitemid 35351504)
-
(2002)
Immunity
, vol.17
, Issue.5
, pp. 583-591
-
-
Kinjyo, I.1
Hanada, T.2
Inagaki-Ohara, K.3
Mori, H.4
Aki, D.5
Ohishi, M.6
Yoshida, H.7
Kubo, M.8
Yoshimura, A.9
-
21
-
-
11144224785
-
Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of Toll-like receptor signaling
-
DOI 10.1074/jbc.M411043200
-
S Gingras, E Parganas, A de Pauw, JN Ihle, and PJ Murray: Re-examination of the role of SOCS1 in the regulation of Toll-like receptor signaling. J. Biol. Chem. 279, 54702-54707 (2004). (Pubitemid 40053214)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.52
, pp. 54702-54707
-
-
Gingras, S.1
Parganas, E.2
De Pauw, A.3
Ihle, J.N.4
Murray, P.J.5
-
22
-
-
11144233242
-
Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells
-
DOI 10.1074/jbc.M410992200
-
A Baetz, M Frey, K Heeg, and AH Dalpke: Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells. J. Biol. Chem. 279, 54708-54715 (2004). (Pubitemid 40053215)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.52
, pp. 54708-54715
-
-
Baetz, A.1
Frey, M.2
Heeg, K.3
Dalpke, A.H.4
-
23
-
-
1542313914
-
Regulation of TLR signaling and inflammation by SOCS family proteins
-
DOI 10.1189/jlb.0403194
-
A Yoshimura, HM Ohishi, D Aki, and T Hanada: Regulation of TLR signaling and inflammation by SOCS family proteins. J Leukoc. Biol. 75, 422-427 (2004). (Pubitemid 38316372)
-
(2004)
Journal of Leukocyte Biology
, vol.75
, Issue.3
, pp. 422-427
-
-
Yoshimura, A.1
Ohishi, H.M.M.2
Aki, D.3
Hanada, T.4
-
24
-
-
0035834171
-
Suppressor of cytokine signaling 3 (SOCS-3) protects β-cells against interleukin-1β- and interferon-γ-mediated toxicity
-
DOI 10.1073/pnas.211445998
-
AE Karlsen, SG Ronn, K Lindberg, J Johannesen, ED Galsgaard, F Pociot, JH Nielsen, T Mandrup-Poulsen, J Nerup, and N Billestrup: Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity. PNAS 98, 12191- 12196 (2001). (Pubitemid 32959849)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.21
, pp. 12191-12196
-
-
Karlsen, A.E.1
Ronn, S.G.2
Lindberg, K.3
Johannesen, J.4
Galsgaard, E.D.5
Pociot, F.6
Nielsen, J.H.7
Mandrup-Poulsen, T.8
Nerup, J.9
Billestrup, N.10
-
25
-
-
33745194935
-
Suppressor of cytokine signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex
-
DOI 10.1210/me.2005-0301
-
H Frobose, SG Ronn, PE Heding, H Mendoza, P Cohen, T Mandrup-Poulsen, and N Billestrup: Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex. Mol. Endocrinol. 20, 1587-1596 (2006). (Pubitemid 43967566)
-
(2006)
Molecular Endocrinology
, vol.20
, Issue.7
, pp. 1587-1596
-
-
Frobose, H.1
Ronn, S.G.2
Heding, P.E.3
Mendoza, H.4
Cohen, P.5
Mandrup-Poulsen, T.6
Billestrup, N.7
-
26
-
-
0347955360
-
Regulation of NF-κB Signaling by Pin1-Dependent Prolyl Isomerization and Ubiquitin-Mediated Proteolysis of p65/RelA
-
DOI 10.1016/S1097-2765(03)00490-8
-
A Ryo, F Suizu, Y Yoshida, K Perrem, YC Liou, G Wulf, R Rottapel, S Yamaoka, and KP Lu: Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol. Cell. 12, 1413-1426 (2003). (Pubitemid 38037011)
-
(2003)
Molecular Cell
, vol.12
, Issue.6
, pp. 1413-1426
-
-
Ryo, A.1
Suizu, F.2
Yoshida, Y.3
Perrem, K.4
Liou, Y.-C.5
Wulf, G.6
Rottapel, R.7
Yamaoka, S.8
Lu, K.P.9
-
27
-
-
79954626520
-
Suppressor of cytokine signaling 1 (SOCS1) limits NF{kappa}B signaling by decreasing p65 stability within the cell nucleus
-
J Strebovsky, P Walker, R Lang, and AH Dalpke: Suppressor of cytokine signaling 1 (SOCS1) limits NF{kappa}B signaling by decreasing p65 stability within the cell nucleus. FASEB J 25, 863-874 (2010).
-
(2010)
FASEB J
, vol.25
, pp. 863-874
-
-
Strebovsky, J.1
Walker, P.2
Lang, R.3
Dalpke, A.H.4
-
28
-
-
33846475712
-
COMMD1 promotes the ubiquitination of NF-κB subunits through a cullin-containing ubiquitin ligase
-
DOI 10.1038/sj.emboj.7601489, PII 7601489
-
GN Maine, X Mao, CM Komarck, and E Burstein: COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. EMBO J. 26, 436-447 (2007). (Pubitemid 46160944)
-
(2007)
EMBO Journal
, vol.26
, Issue.2
, pp. 436-447
-
-
Maine, G.N.1
Mao, X.2
Komarck, C.M.3
Burstein, E.4
-
29
-
-
54949147176
-
New regulators of NFkappaB in inflammation
-
S Ghosh, and MS Hayden: New regulators of NFkappaB in inflammation. Nat. Rev. Immunol. 8, 837-848 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 837-848
-
-
Ghosh, S.1
Hayden, M.S.2
-
30
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
-
WS Alexander, and DJ Hilton: The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu. Rev. Immunol 22, 503-529 (2003).
-
(2003)
Annu. Rev. Immunol
, vol.22
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
31
-
-
0032772125
-
Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice
-
A Matsumoto, Y Seki, M Kubo, S Ohtsuka, A Suzuki, I Hayashi, K Tsuji, T Nakahata, M Okabe, S Yamada, and A Yoshimura: Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2- containing protein 1 transgenic mice. Mol. Cell Biol. 19, 6396-6407 (1999). (Pubitemid 29399343)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.9
, pp. 6396-6407
-
-
Matsumoto, A.1
Seki, Y.2
Kubo, M.3
Ohtsuka, S.4
Suzuki, A.5
Hayashi, I.6
Tsuji, K.7
Nakahata, T.8
Okabe, M.9
Yamada, S.10
Yoshimura, A.11
-
32
-
-
0034703097
-
CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2
-
DOI 10.1074/jbc.M003456200
-
A Sasaki, H Yasukawa, T Shouda, T Kitamura, I Dikic, and A Yoshimura: CIS3/SOCS3 suppresses erythropoietin signaling by binding the EPO receptor and JAK2. J. Biol. Chem. 275, 29338-29347 (2000). (Pubitemid 32043805)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.38
, pp. 29338-29347
-
-
Sasaki, A.1
Yasukawa, H.2
Shouda, T.3
Kitamura, T.4
Dikic, I.5
Yoshimura, A.6
-
33
-
-
20144380439
-
SOCS2 negatively regulates growth hormone action in vitro and in vivo
-
DOI 10.1172/JCI200522710
-
CJ Greenhalgh, E Rico-Bautista, M Lorentzon, AL Thaus, PO Morgan, TA Willson, P Zervoudakis, D Metcalf, I Street, NA Nicola, AD Nash, LJ Fabri, G Norstedt, C Ohlsson, A Flores-Morales, WS Alexander, and DJ Hilton: SOCS2 negatively regulates growth hormone action in vitro and in vivo. J Clin. Invest 115, 397- 406 (2005). (Pubitemid 40385481)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.2
, pp. 397-406
-
-
Greenhalgh, C.J.1
Rico-Bautista, E.2
Lorentzon, M.3
Thaus, A.L.4
Morgan, P.O.5
Willson, T.A.6
Zervoudakis, P.7
Metcalf, D.8
Street, I.9
Nicola, N.A.10
Nash, A.D.11
Fabri, L.J.12
Norstedt, G.13
Ohlsson, C.14
Flores-Morales, A.15
Alexander, W.S.16
Hilton, D.J.17
-
34
-
-
0034729710
-
Gigantism in mice lacking suppressor of cytokine signalling-2
-
DOI 10.1038/35016611
-
Metcalf D, CJ Greenhalgh, EM Viney, TA Willson, R Starr, NA Nicola, D Hilton, and WS Alexander: Gigantism in mice lacking suppressor of cytokine signalling-2. Nature 405, 1069-1073 (2000). (Pubitemid 30447793)
-
(2000)
Nature
, vol.405
, Issue.6790
, pp. 1069-1073
-
-
Metcalf, D.1
Greenhalgh, C.J.2
Viney, E.3
Wilison, T.A.4
Starr, R.5
Nicola, N.A.6
Hilton, D.J.7
Alexander, W.S.8
-
35
-
-
20244389693
-
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
-
H Yasukawa, H Misawa, H Sakamoto, M Masuhara, A Sasaki, T Wakioka, S Ohtsuka, T Imaizumi, T Matsuda, JN Ihle, and A Yoshimura: The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J. 18, 1309-1320 (1999). (Pubitemid 29110315)
-
(1999)
EMBO Journal
, vol.18
, Issue.5
, pp. 1309-1320
-
-
Yasukawa, H.1
Misawa, H.2
Sakamoto, H.3
Masuhara, M.4
Sasaki, A.5
Wakioka, T.6
Ohtsuka, S.7
Imaizumi, T.8
Matsuda, T.9
Ihle, J.N.10
Yoshimura, A.11
-
36
-
-
0037317179
-
A three-dimensional model of suppressor of cytokine signalling 1 (SOCS-1)
-
F Giordanetto, and RT Kroemer: A three-dimensional model of Suppressor Of Cytokine Signalling 1 (SOCS-1). Protein. Eng. 16, 115-124 (2003). (Pubitemid 36458650)
-
(2003)
Protein Engineering
, vol.16
, Issue.2
, pp. 115-124
-
-
Giordanetto, F.1
Kroemer, R.T.2
-
37
-
-
0034724677
-
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
-
DOI 10.1074/jbc.275.17.12848
-
J Schmitz, M Weissenbach, S Haan, PC Heinrich, and F Schaper: SOCS3 Exerts Its Inhibitory Function on Interleukin-6 Signal Transduction through the SHP2 Recruitment Site of gp130. J. Biol. Chem. 275, 12848- 12856 (2000). (Pubitemid 30241440)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.17
, pp. 12848-12856
-
-
Schmitz, J.1
Weissenbach, M.2
Haan, S.3
Heinrich, P.C.4
Schaper, F.5
-
38
-
-
0034612271
-
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2- binding site on the shared cytokine receptor subunit gp130
-
DOI 10.1073/pnas.100135197
-
SE Nicholson, D De Souza, LJ Fabri, J Corbin, TA Willson, JG Zhang, A Silva, M Asimakis, A Farley, AD Nash, D Metcalf, DJ Hilton, NA Nicola, and M Baca: Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130. PNAS 97, 6493-6498 (2000). (Pubitemid 30412741)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.12
, pp. 6493-6498
-
-
Nicholson, S.E.1
De Souza, D.2
Fabri, L.J.3
Corbin, J.4
Willson, T.A.5
Zhang, J.-G.6
Silva, A.7
Asimakis, M.8
Farley, A.9
Nash, A.D.10
Metcalf, D.11
Hilton, D.J.12
Nicola, N.A.13
Baca, M.14
-
39
-
-
0036681955
-
Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
-
M Hortner, U Nielsch, LM Mayr, JA Johnston, PC Heinrich, and S Haan: Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction. J Immunol 169, 1219-1227 (2002). (Pubitemid 34809162)
-
(2002)
Journal of Immunology
, vol.169
, Issue.3
, pp. 1219-1227
-
-
Hortner, M.1
Nielsch, U.2
Mayr, L.M.3
Johnston, J.A.4
Heinrich, P.C.5
Haan, S.6
-
40
-
-
0001421697
-
985
-
DOI 10.1074/jbc.M007577200
-
C Bjorbaek, HJ Lavery, SH Bates, RK Olson, SM Davis, JS Flier, and MG Myers Jr.: SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985. J. Biol. Chem. 275, 40649-40657 (2000). (Pubitemid 32064706)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.51
, pp. 40649-40657
-
-
Bjorbaek, C.1
Lavery, H.J.2
Bates, S.H.3
Olson, R.K.4
Davis, S.M.5
Flier, J.S.6
Myers Jr., M.G.7
-
41
-
-
0034548763
-
Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor
-
S Eyckerman, D Broekaert, A Verhee, J Vandekerckhove, and J Tavernier: Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor. FEBS Lett. 486, 33-37 (2000).
-
(2000)
FEBS Lett
, vol.486
, pp. 33-37
-
-
Eyckerman, S.1
Broekaert, D.2
Verhee, A.3
Vandekerckhove, J.4
Tavernier, J.5
-
42
-
-
0033544899
-
SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms
-
PA Ram, and DJ Waxman: SOCS/CIS Protein Inhibition of Growth Hormone-stimulated STAT5 Signaling by Multiple Mechanisms. J. Biol. Chem. 274, 35553-35561 (1999). (Pubitemid 129512851)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.50
, pp. 35553-35561
-
-
Ram, P.A.1
Waxman, D.J.2
-
43
-
-
2942615015
-
Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function
-
LO Flowers, HM Johnson, MG Mujtaba, MR Ellis, SM Haider, and PS Subramaniam: Characterization of a Peptide Inhibitor of Janus Kinase 2 That Mimics Suppressor of Cytokine Signaling 1 Function. J Immunol 172, 7510-7518 (2004). (Pubitemid 38747614)
-
(2004)
Journal of Immunology
, vol.172
, Issue.12
, pp. 7510-7518
-
-
Flowers, L.O.1
Johnson, H.M.2
Mujtaba, M.G.3
Ellis, M.R.4
Haider, S.M.I.5
Subramaniam, P.S.6
-
44
-
-
23844524089
-
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis
-
DOI 10.1038/nm1269
-
D Jo, D Liu, S Yao, RD Collins, and J Hawiger: Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis. Nat. Med 11, 892-898 (2005). (Pubitemid 41161123)
-
(2005)
Nature Medicine
, vol.11
, Issue.8
, pp. 892-898
-
-
Jo, D.1
Liu, D.2
Yao, S.3
Collins, R.D.4
Hawiger, J.5
-
45
-
-
77953302258
-
Extended anti-inflammatory action of a degradationresistant mutant of cell-penetrating suppressor of cytokine signaling 3
-
TC Fletcher, A DiGiandomenico, and J Hawiger: Extended anti-inflammatory action of a degradationresistant mutant of cell-penetrating suppressor of cytokine signaling 3. J. Biol Chem. 285, 18727-18736 (2010).
-
(2010)
J. Biol Chem.
, vol.285
, pp. 18727-18736
-
-
Fletcher, T.C.1
Digiandomenico, A.2
Hawiger, J.3
-
46
-
-
13044263097
-
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
-
DOI 10.1073/pnas.96.5.2071
-
JG Zhang, A Farley, SE Nicholson, TA Willson, LM Zugaro, RJ Simpson, RL Moritz, D Cary, R Richardson, G Hausmann, BJ Kile, SB Kent, WS Alexander, D Metcalf, DJ Hilton, NA Nicola, and M Baca: The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. PNAS 96, 2071-2076 (1999). (Pubitemid 29117869)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.5
, pp. 2071-2076
-
-
Zhang, J.-G.1
Farley, A.2
Nicholson, S.E.3
Willson, T.A.4
Zugaro, L.M.5
Simpson, R.J.6
Moritz, R.L.7
Cary, D.8
Richardson, R.9
Hausmann, G.10
Kile, B.J.11
Kent, S.B.H.12
Alexander, W.S.13
Metcalf, D.14
Hilton, D.J.15
Nicola, N.A.16
Baca, M.17
-
47
-
-
0035918239
-
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2
-
S Kamizono, T Hanada, H Yasukawa, S Minoguchi, R Kato, M Minoguchi, K Hattori, S Hatakeyama, M Yada, S Morita, T Kitamura, H Kato, K Nakayama, and A Yoshimura: The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. J. Biol. Chem. 276, 12530-12538 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12530-12538
-
-
Kamizono, S.1
Hanada, T.2
Yasukawa, H.3
Minoguchi, S.4
Kato, R.5
Minoguchi, M.6
Hattori, K.7
Hatakeyama, S.8
Yada, M.9
Morita, S.10
Kitamura, T.11
Kato, H.12
Nakayama, K.13
Yoshimura, A.14
-
48
-
-
57049091056
-
The many faces of the SOCS box
-
J Piessevaux, D Lavens, F Peelman, and J Tavernier: The many faces of the SOCS box. Cytokine Growth Factor Rev. 19, 371-381 (2008).
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 371-381
-
-
Piessevaux, J.1
Lavens, D.2
Peelman, F.3
Tavernier, J.4
-
49
-
-
0035818573
-
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo
-
DOI 10.1073/pnas.231486498
-
JG Zhang, D Metcalf, S Rakar, M Asimakis, CJ Greenhalgh, TA Willson, R Starr, SE Nicholson, W Carter, WS Alexander, DJ Hilton, and NA Nicola: The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo. PNAS 98, 13261-13265 (2001). (Pubitemid 33051350)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.23
, pp. 13261-13265
-
-
Zhang, J.-G.1
Metcalf, D.2
Rakar, S.3
Asimakis, M.4
Greenhalgh, C.J.5
Willson, T.A.6
Starr, R.7
Nicholson, S.E.8
Carter, W.9
Alexander, W.S.10
Hilton, D.J.11
Nicola, N.A.12
-
50
-
-
0042357098
-
Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation
-
DOI 10.1074/jbc.M303170200
-
S Haan, P Ferguson, U Sommer, M Hiremath, D McVicar, PC Heinrich, JA Johnston, and NA Cacalano: Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation. J. Biol. Chem. 278, 31972-31979 (2003). (Pubitemid 37048385)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.34
, pp. 31972-31979
-
-
Haan, S.1
Ferguson, P.2
Sommer, U.3
Hiremath, M.4
McVicar, D.W.5
Heinrich, P.C.6
Johnston, J.A.7
Cacalano, N.A.8
-
51
-
-
0032535364
-
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families
-
T Kamura, Sato S, D Haque, L Liu, WGJ Kaelin, RC Conaway, and JW Conaway: The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families. Genes Dev. 12, 3872-3881 (1998). (Pubitemid 29024849)
-
(1998)
Genes and Development
, vol.12
, Issue.24
, pp. 3872-3881
-
-
Kamura, T.1
Sato, S.2
Haque, D.3
Liu, L.4
Kaelin Jr., W.G.5
Conaway, R.C.6
Conaway, J.W.7
-
52
-
-
0001421104
-
Different protein turnover of interleukin-6-type cytokine signalling components
-
DOI 10.1046/j.1432-1327.1999.00719.x
-
E Siewert, W Muller-Esterl, R Starr, PC Heinrich, and F Schaper: Different protein turnover of interleukin-6-type cytokine signalling components. Eur. J Biochem. 265, 251-257 (1999). (Pubitemid 29466033)
-
(1999)
European Journal of Biochemistry
, vol.265
, Issue.1
, pp. 251-257
-
-
Siewert, E.1
Muller-Esterl, W.2
Starr, R.3
Heinrich, P.C.4
Schaper, F.5
-
53
-
-
0036413509
-
Preparation and expression of biologically active prolactin and growth hormone receptors and suppressor of cytokine signaling proteins 1, 2, 3, and 6 tagged with cyan and yellow fluorescent proteins
-
L Ben Yair, R Slaaby, A Herman, Y Cohen, E Biener, N Moran, A Yoshimura, J Whittaker, P De Meyts, B Herman, and A Gertler: Preparation and expression of biologically active prolactin and growth hormone receptors and suppressor of cytokine signaling proteins 1, 2, 3, and 6 tagged with cyan and yellow fluorescent proteins. Protein Expr. Purif. 25, 456 (2002).
-
(2002)
Protein Expr. Purif.
, vol.25
, pp. 456
-
-
Yair, L.B.1
Slaaby, R.2
Herman, A.3
Cohen, Y.4
Biener, E.5
Moran, N.6
Yoshimura, A.7
Whittaker, J.8
Meyts, P.D.9
Herman, B.10
Gertler, A.11
-
54
-
-
2442428140
-
SOC1 inhibits HPV-E7-mediated transformation by inducing degradation of E7 protein
-
DOI 10.1038/sj.onc.1207453
-
M Kamio, T Yoshida, H Ogata, T Douchi, Y Nagata, M Inoue, M Hasegawa, Y Yonemitsu, and A Yoshimura: SOCS1 [corrected] inhibits HPV-E7-mediated transformation by inducing degradation of E7 protein. Oncogene. 23, 3107-3115 (2004). (Pubitemid 38648201)
-
(2004)
Oncogene
, vol.23
, Issue.17
, pp. 3107-3115
-
-
Kamio, M.1
Yoshida, T.2
Ogata, H.3
Douchi, T.4
Nagata, Y.5
Inoue, M.6
Hasegawa, M.7
Yonemitsu, Y.8
Yoshimura, A.9
-
55
-
-
4744363325
-
SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome
-
DOI 10.1128/MCB.24.20.9092-9101.2004
-
BQ Vuong, TL Arenzana, BM Showalter, J Losman, XP Chen, J Mostecki, AS Banks, A Limnander, N Fernandez, and PB Rothman: SOCS-1 Localizes to the Microtubule Organizing Complex-Associated 20S Proteasome. Mol. Cell Biol. 24, 9092-9101 (2004). (Pubitemid 39313913)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.20
, pp. 9092-9101
-
-
Vuong, B.Q.1
Arenzana, T.L.2
Showalter, B.M.3
Losman, J.4
Chen, X.P.5
Mostecki, J.6
Banks, A.S.7
Limnander, A.8
Fernandez, N.9
Rothman, P.B.10
-
56
-
-
77956922435
-
The IFN-{gamma}-Dependent suppressor of cytokine signaling 1 Promoter Activity Is Positively Regulated by IFN Regulatory Factor-1 and Sp1 but Repressed by Growth Factor Independence-1b and Kruppel-Like Factor-4, and It Is Dysregulated in Psoriatic Keratinocytes
-
S Madonna, C Scarponi, R Sestito, S Pallotta, A Cavani, and C Albanesi: The IFN-{gamma}-Dependent suppressor of cytokine signaling 1 Promoter Activity Is Positively Regulated by IFN Regulatory Factor-1 and Sp1 but Repressed by Growth Factor Independence-1b and Kruppel-Like Factor-4, and It Is Dysregulated in Psoriatic Keratinocytes. J. Immunol. 185, 2467-2481 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 2467-2481
-
-
Madonna, S.1
Scarponi, C.2
Sestito, R.3
Pallotta, S.4
Cavani, A.5
Albanesi, C.6
-
57
-
-
52049098945
-
Interaction and functional interference of glucocorticoid receptor and SOCS1
-
MC Haffner, A Jurgeit, C Berlato, S Geley, N Parajuli, A Yoshimura, and W Doppler: Interaction and functional interference of glucocorticoid receptor and SOCS1. J Biol Chem. 283, 22089-22096 (2008).
-
(2008)
J Biol Chem.
, vol.283
, pp. 22089-22096
-
-
Haffner, M.C.1
Jurgeit, A.2
Berlato, C.3
Geley, S.4
Parajuli, N.5
Yoshimura, A.6
Doppler, W.7
-
58
-
-
46549086459
-
Increased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation
-
KH Lee, KJ Moon, HS Kim, BC Yoo, S Park, H Lee, S Kwon, ES Lee, and S Yoon: Increased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation. FEBS Lett. 582, 2319-2324 (2008).
-
(2008)
FEBS Lett
, vol.582
, pp. 2319-2324
-
-
Lee, K.H.1
Moon, K.J.2
Kim, H.S.3
Yoo, B.C.4
Park, S.5
Lee, H.6
Kwon, S.7
Lee, E.S.8
Yoon, S.9
-
59
-
-
57349102472
-
Identification of a nuclear localization signal in suppressor of cytokine signaling 1
-
A Baetz, C Koelsche, J Strebovsky, K Heeg, and AH Dalpke: Identification of a nuclear localization signal in suppressor of cytokine signaling 1. FASEB J 22, 4296-4305 (2008).
-
(2008)
FASEB J
, vol.22
, pp. 4296-4305
-
-
Baetz, A.1
Koelsche, C.2
Strebovsky, J.3
Heeg, K.4
Dalpke, A.H.5
-
60
-
-
67650354017
-
Structural and functional analysis of a nuclear localization signal in SOCS1
-
C Koelsche, J Strebovsky, A Baetz, and AH Dalpke: Structural and functional analysis of a nuclear localization signal in SOCS1. Mol. Immunol. 46, 2474-2480 (2009).
-
(2009)
Mol. Immunol.
, vol.46
, pp. 2474-2480
-
-
Koelsche, C.1
Strebovsky, J.2
Baetz, A.3
Dalpke, A.H.4
-
61
-
-
69249222891
-
Nuclear localization signals and human disease
-
LM McLane, and AH Corbett: Nuclear localization signals and human disease. IUBMB. Life 61, 697-706 (2009).
-
(2009)
IUBMB. Life
, vol.61
, pp. 697-706
-
-
McLane, L.M.1
Corbett, A.H.2
-
62
-
-
34548289288
-
Septins Regulate Actin Organization and Cell-Cycle Arrest through Nuclear Accumulation of NCK Mediated by SOCS7
-
DOI 10.1016/j.cell.2007.06.053, PII S0092867407009038
-
BE Kremer, LA Adang, and IG Macara: Septins Regulate Actin Organization and Cell-Cycle Arrest through Nuclear Accumulation of NCK Mediated by SOCS7. Cell 130, 837- 850 (2007). (Pubitemid 47332569)
-
(2007)
Cell
, vol.130
, Issue.5
, pp. 837-850
-
-
Kremer, B.E.1
Adang, L.A.2
Macara, I.G.3
-
63
-
-
34447288769
-
The nuclear localization of SOCS6 requires the N-terminal region and negatively regulates Stat3 protein levels
-
DOI 10.1016/j.bbrc.2007.06.062, PII S0006291X0701251X
-
MN Hwang, CH Min, HS Kim, H Lee, KA Yoon, SY Park, ES Lee, and S Yoon: The nuclear localization of SOCS6 requires the N-terminal region and negatively regulates Stat3 protein levels. Biochem. Biophys. Res Commun. 360, 333-338 (2007). (Pubitemid 47044839)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.360
, Issue.2
, pp. 333-338
-
-
Hwang, M.-N.1
Min, C.-H.2
Kim, H.S.3
Lee, H.4
Yoon, K.-A.5
Park, S.Y.6
Lee, E.S.7
Yoon, S.8
-
64
-
-
79954591379
-
Suppressor of cytokine signalling protein SOCS3 expression is increased at sites of acute and chronic inflammation
-
epub ahead of print
-
GE White, A Cotterill, MR Addley, EJ Soilleux, and DR Greaves: Suppressor of cytokine signalling protein SOCS3 expression is increased at sites of acute and chronic inflammation. J Mol. Histol. epub ahead of print, (2011).
-
(2011)
J Mol. Histol.
-
-
White, G.E.1
Cotterill, A.2
Addley, M.R.3
Soilleux, E.J.4
Greaves, D.R.5
-
65
-
-
0033520467
-
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
-
DOI 10.1016/S0092-8674(00)80048-3
-
JC Marine, DJ Topham, C McKay, D Wang, E Parganas, D Stravopodis, A Yoshimura, and JN Ihle: SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell 98, 609-616 (1999). (Pubitemid 29418952)
-
(1999)
Cell
, vol.98
, Issue.5
, pp. 609-616
-
-
Marine, J.-C.1
Topham, D.J.2
McKay, C.3
Wang, D.4
Parganas, E.5
Stravopodis, D.6
Yoshimura, A.7
Ihle, J.N.8
-
66
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon γ signaling and prevents the potentially fatal neonatal actions of this cytokine
-
DOI 10.1016/S0092-8674(00)80047-1
-
WS Alexander, R Starr, JE Fenner, CL Scott, E Handman, NS Sprigg, JE Corbin, AL Cornish, R Darwiche, CM Owczarek, TW Kay, NA Nicola, PJ Hertzog, D Metcalf, and DJ Hilton: SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 98, 597-608 (1999). (Pubitemid 29418951)
-
(1999)
Cell
, vol.98
, Issue.5
, pp. 597-608
-
-
Alexander, W.S.1
Starr, R.2
Fenner, J.E.3
Scott, C.L.4
Handman, E.5
Sprigg, N.S.6
Corbin, J.E.7
Cornish, A.L.8
Darwiche, R.9
Owczarek, C.M.10
Kay, T.W.H.11
Nicola, N.A.12
Hertzog, P.J.13
Metcalf, D.14
Hilton, D.J.15
-
67
-
-
13044276245
-
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice
-
DOI 10.1073/pnas.95.26.15577
-
T Naka, T Matsumoto, M Narazaki, M Fujimoto, Y Morita, Y Ohsawa, H Saito, T Nagasawa, Y Uchiyama, and T Kishimoto: Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice. PNAS 95, 15577-15582 (1998). (Pubitemid 29018741)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.26
, pp. 15577-15582
-
-
Naka, T.1
Matsumoto, T.2
Narazaki, M.3
Fujimoto, M.4
Morita, Y.5
Ohsawa, Y.6
Saito, H.7
Nagasawa, T.8
Uchiyama, Y.9
Kishimoto, T.10
-
68
-
-
0032564463
-
Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1
-
DOI 10.1073/pnas.95.24.14395
-
R Starr, D Metcalf, AG Elefanty, M Brysha, TA Willson, NA Nicola, DJ Hilton, and WS Alexander: Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1. PNAS 95, 14395-14399 (1998). (Pubitemid 28549378)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.24
, pp. 14395-14399
-
-
Starr, R.1
Metcalf, D.2
Elefanty, A.G.3
Brysha, M.4
Willson, T.A.5
Nicola, N.A.6
Hilton, D.J.7
Alexander, W.S.8
-
69
-
-
0034792866
-
Neutralization of interferon-gamma in neonatal SOCS1-/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease
-
DV Bullen, R Darwiche, D Metcalf, E Handman, and WS Alexander: Neutralization of interferon-gamma in neonatal SOCS1-/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease. Immunology 104, 92-98 (2001).
-
(2001)
Immunology
, vol.104
, pp. 92-98
-
-
Bullen, D.V.1
Darwiche, R.2
Metcalf, D.3
Handman, E.4
Alexander, W.S.5
-
70
-
-
0037154210
-
Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1)
-
DOI 10.1073/pnas.022628499
-
D Metcalf, S Mifsud, L Di Rago, NA Nicola, DJ Hilton, and WS Alexander: Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1). PNAS 99, 943-948 (2002). (Pubitemid 34106615)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.2
, pp. 943-948
-
-
Metcalf, D.1
Mifsud, S.2
Di Rago, L.3
Nicola, N.A.4
Hilton, D.J.5
Alexander, W.S.6
-
71
-
-
0035168683
-
JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling
-
DOI 10.1182/blood.V97.1.221
-
B Sporri, PE Kovanen, A Sasaki, A Yoshimura, and WJ Leonard: JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling. Blood 97, 221-226 (2001). (Pubitemid 32061264)
-
(2001)
Blood
, vol.97
, Issue.1
, pp. 221-226
-
-
Sporri, B.1
Kovanen, P.E.2
Sasaki, A.3
Yoshimura, A.4
Leonard, W.J.5
-
72
-
-
0037927824
-
Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other γc-dependent cytokines in peripheral T cells
-
DOI 10.1074/jbc.M303021200
-
AL Cornish, MM Chong, GM Davey, R Darwiche, NA Nicola, DJ Hilton, TW Kay, R Starr, and WS Alexander: Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells. J Biol Chem. 278, 22755- 22761 (2003). (Pubitemid 36830336)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22755-22761
-
-
Cornish, A.L.1
Chong, M.M.2
Davey, G.M.3
Darwiche, R.4
Nicola, N.A.5
Hilton, D.J.6
Kay, T.W.7
Starr, R.8
Alexander, W.S.9
-
73
-
-
0034502224
-
Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1
-
DOI 10.1016/S1074-7613(00)00078-9
-
S Diehl, J Anguita, A Hoffmeyer, T Zapton, JN Ihle, E Fikrig, and M Rincon: Inhibition of Th1 differentiation by IL-6 is mediated by SOCS1. Immunity 13, 805-815 (2000). (Pubitemid 32041803)
-
(2000)
Immunity
, vol.13
, Issue.6
, pp. 805-815
-
-
Diehl, S.1
Anguita, J.2
Hoffmeyer, A.3
Zapton, T.4
Ihle, J.N.5
Fikrig, E.6
Rincon, M.7
-
74
-
-
0038807434
-
Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1
-
DOI 10.1074/jbc.M208586200
-
JL Eyles, D Metcalf, MJ Grusby, DJ Hilton, and R Starr: Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1. J. Biol. Chem. 277, 43735-43740 (2002). (Pubitemid 36157791)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 43735-43740
-
-
Eyles, J.L.1
Metcalf, D.2
Grusby, M.J.3
Hilton, D.J.4
Starr, R.5
-
75
-
-
0042931134
-
high memory T lymphocytes
-
S Ilangumaran, S Ramanathan, J La Rose, P Poussier, and R Rottapel: Suppressor of Cytokine Signaling 1 Regulates IL-15 Receptor Signaling in CD8+CD44high Memory T Lymphocytes. J Immunol 171, 2435-2445 (2003). (Pubitemid 37025551)
-
(2003)
Journal of Immunology
, vol.171
, Issue.5
, pp. 2435-2445
-
-
Ilangumaran, S.1
Ramanathan, S.2
La Rose, J.3
Poussier, P.4
Rottapel, R.5
-
76
-
-
0034624986
-
Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses necrosis factor α-induced cell death in fibroblasts
-
DOI 10.1073/pnas.090084797
-
Y Morita, T Naka, Y Kawazoe, M Fujimoto, M Narazaki, R Nakagawa, H Fukuyama, S Nagata, and T Kishimoto: Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI- 1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha -induced cell death in fibroblasts. PNAS 97, 5405-5410 (2000). (Pubitemid 30313731)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.10
, pp. 5405-5410
-
-
Morita, Y.1
Naka, T.2
Kawazoe, Y.3
Fujimoto, M.4
Narazaki, M.5
Nakagawa, R.6
Fukuyama, H.7
Nagata, S.8
Kishimoto, T.9
-
77
-
-
10744223505
-
Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity
-
DOI 10.1016/S1074-7613(03)00240-1
-
T Hanada, H Yoshida, S Kato, K Tanaka, K Masutani, J Tsukada, Y Nomura, H Mimata, M Kubo, and A Yoshimura: Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity. Immunity 19, 437-450 (2003). (Pubitemid 37153419)
-
(2003)
Immunity
, vol.19
, Issue.3
, pp. 437-450
-
-
Hanada, T.1
Yoshida, H.2
Kato, S.3
Tanaka, K.4
Masutani, K.5
Tsukada, J.6
Nomura, Y.7
Mimata, H.8
Kubo, M.9
Yoshimura, A.10
-
78
-
-
31044453678
-
SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling
-
DOI 10.1172/JCI26169
-
K Evel-Kabler, XT Song, M Aldrich, XF Huang, and SY Chen: SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling. J Clin. Invest. 116, 90-100 (2006). (Pubitemid 43121794)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.1
, pp. 90-100
-
-
Evel-Kabler, K.1
Song, X.-T.2
Aldrich, M.3
Huang, X.F.4
Chen, S.-Y.5
-
79
-
-
33845479440
-
Involvement of suppressors of cytokine signaling in toll-like receptor-mediated block of dendritic cell differentiation
-
DOI 10.1182/blood-2006-03-008946
-
H Bartz, NM Avalos, A Baetz, K Heeg, and AH Dalpke: Involvement of suppressors of cytokine signaling in toll-like receptor-mediated block of dendritic cell differentiation. Blood 108, 4102-4108 (2006). (Pubitemid 44913281)
-
(2006)
Blood
, vol.108
, Issue.13
, pp. 4102-4108
-
-
Bartz, H.1
Avalos, N.M.2
Baetz, A.3
Heeg, K.4
Dalpke, A.H.5
-
80
-
-
0842278641
-
Dendritic cell maturation requires STAT1 and is under feedback regulation by suppressors of cytokine signaling
-
SH Jackson, CR Yu, RM Mahdi, S Ebong, and CE Egwuagu: Dendritic Cell Maturation Requires STAT1 and Is under Feedback Regulation by Suppressors of Cytokine Signaling. J Immunol 172, 2307-2315 (2004). (Pubitemid 38182378)
-
(2004)
Journal of Immunology
, vol.172
, Issue.4
, pp. 2307-2315
-
-
Jackson, S.H.1
Yu, C.-R.2
Mahdi, R.M.3
Ebong, S.4
Egwuagu, C.E.5
-
81
-
-
79955967742
-
MiR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1
-
C Lu, X Huang, X Zhang, K Roensch, Q Cao, KI Nakayama, BR Blazar, Y Zeng, and X Zhou: miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1. Blood 117, 4293-4303 (2011).
-
(2011)
Blood
, vol.117
, pp. 4293-4303
-
-
Lu, C.1
Huang, X.2
Zhang, X.3
Roensch, K.4
Cao, Q.5
Nakayama, K.I.6
Blazar, B.R.7
Zeng, Y.8
Zhou, X.9
-
82
-
-
20144364619
-
Induction of hyper Th1 cell-type immune responses by dendritic cells lacking the suppressor of cytokine signaling-1 gene
-
T Hanada, K Tanaka, Y Matsumura, M Yamauchi, H Nishinakamura, H Aburatani, R Mashima, M Kubo, T Kobayashi, and A Yoshimura: Induction of Hyper Th1 Cell-Type Immune Responses by Dendritic Cells Lacking the Suppressor of Cytokine Signaling-1 Gene. J Immunol 174, 4325-4332 (2005). (Pubitemid 40396015)
-
(2005)
Journal of Immunology
, vol.174
, Issue.7
, pp. 4325-4332
-
-
Hanada, T.1
Tanaka, K.2
Matsumura, Y.3
Yamauchi, M.4
Nishinakamura, H.5
Aburatani, H.6
Mashima, R.7
Kubo, M.8
Kobayashi, T.9
Yoshimura, A.10
-
83
-
-
70350005164
-
TLR2 and DC-SIGNR1 differentially regulate suppressors of cytokine signaling 1 in dendritic cells during Mycobacterium tuberculosis infection
-
V Srivastava, M Manchanda, S Gupta, R Singla, D Behera, G Das, and K Natarajan: TLR2 and DC-SIGNR1 differentially regulate suppressors of cytokine signaling 1 in dendritic cells during Mycobacterium tuberculosis infection. J. Biol Chem. 284, 25532-25541 (2009).
-
(2009)
J. Biol Chem.
, vol.284
, pp. 25532-25541
-
-
Srivastava, V.1
Manchanda, M.2
Gupta, S.3
Singla, R.4
Behera, D.5
Das, G.6
Natarajan, K.7
-
84
-
-
57549106223
-
Donor bone-marrow suppressor of cytokine signaling-1-silenced dendritic cells prolong rat intestinal allograft survival
-
C Zhu, H Xu, J Zhang, K Wang, and P Zhu: Donor bone-marrow suppressor of cytokine signaling-1-silenced dendritic cells prolong rat intestinal allograft survival. Transplant. Proc. 40, 3707-3710 (2008).
-
(2008)
Transplant. Proc.
, vol.40
, pp. 3707-3710
-
-
Zhu, C.1
Xu, H.2
Zhang, J.3
Wang, K.4
Zhu, P.5
-
85
-
-
79952761607
-
Cross-talk between programmed death-1 and suppressor of cytokine signaling-1 in inhibition of IL-12 production by monocytes/macrophages in hepatitis C virus infection
-
Y Zhang, CJ Ma, L Ni, CL Zhang, XY Wu, U Kumaraguru, CF Li, JP Moorman, and ZQ Yao: Cross-Talk between Programmed Death-1 and Suppressor of Cytokine Signaling-1 in Inhibition of IL-12 Production by Monocytes/Macrophages in Hepatitis C Virus Infection. J Immunol. 183, 3093-3103 (2011).
-
(2011)
J Immunol.
, vol.183
, pp. 3093-3103
-
-
Zhang, Y.1
Ma, C.J.2
Ni, L.3
Zhang, C.L.4
Wu, X.Y.5
Kumaraguru, U.6
Li, C.F.7
Moorman, J.P.8
Yao, Z.Q.9
-
86
-
-
0038614944
-
SOCS3 regulates the plasticity of gp130 signaling
-
DOI 10.1038/ni932
-
R Lang, AL Pauleau, E Parganas, Y Takahashi, J Mages, JN Ihle, R Rutschman, and PJ Murray: SOCS3 regulates the plasticity of gp130 signaling. Nat. Immunol. 4, 546-550 (2003). (Pubitemid 36701337)
-
(2003)
Nature Immunology
, vol.4
, Issue.6
, pp. 546-550
-
-
Lang, R.1
Pauleau, A.-L.2
Parganas, E.3
Takahashi, Y.4
Mages, J.5
Ihle, J.N.6
Rutschman, R.7
Murray, P.J.8
-
87
-
-
0037938816
-
SOCS3 negatively regulates IL-6 signaling in vivo
-
DOI 10.1038/ni931
-
BA Croker, DL Krebs, JG Zhang, S Wormald, TA Willson, EG Stanley, L Robb, CJ Greenhalgh, I Forster, BE Clausen, NA Nicola, D Metcalf, DJ Hilton, AW Roberts, and WS Alexander: SOCS3 negatively regulates IL-6 signaling in vivo. Nat. Immunol. 4, 540-545 (2003). (Pubitemid 36701336)
-
(2003)
Nature Immunology
, vol.4
, Issue.6
, pp. 540-545
-
-
Croker, B.A.1
Krebs, D.L.2
Zhang, J.-G.3
Wormald, S.4
Willson, T.A.5
Stanley, E.G.6
Robb, L.7
Greenhalgh, C.J.8
Forster, I.9
Clausen, B.E.10
Nicola, N.A.11
Metcalf, D.12
Hilton, D.J.13
Roberts, A.W.14
Alexander, W.S.15
-
88
-
-
0037600741
-
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
-
DOI 10.1038/ni938
-
H Yasukawa, M Ohishi, H Mori, M Murakami, T Chinen, D Aki, T Hanada, K Takeda, S Akira, M Hoshijima, T Hirano, KR Chien, and A Yoshimura: IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat. Immunol. 4, 551-556 (2003). (Pubitemid 36701338)
-
(2003)
Nature Immunology
, vol.4
, Issue.6
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
Murakami, M.4
Chinen, T.5
Aki, D.6
Hanada, T.7
Takeda, K.8
Akira, S.9
Hoshijima, M.10
Hirano, T.11
Chien, K.R.12
Yoshimura, A.13
-
89
-
-
0037443661
-
Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
-
C Niemand, A Nimmesgern, S Haan, P Fischer, F Schaper, R Rossaint, PC Heinrich, and G Muller-Newen: Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3. J Immunol 170, 3263-3272 (2003). (Pubitemid 36302204)
-
(2003)
Journal of Immunology
, vol.170
, Issue.6
, pp. 3263-3272
-
-
Niemand, C.1
Nimmesgern, A.2
Haan, S.3
Fischer, P.4
Schaper, F.5
Rossaint, R.6
Heinrich, P.C.7
Muller-Newen, G.8
-
90
-
-
0346157324
-
Acquiring signalling specificity from the cytokine receptor gp130
-
DOI 10.1016/j.tig.2003.11.003
-
M Ernst, and BJ Jenkins: Acquiring signalling specificity from the cytokine receptor gp130. Trends Genet. 20, 23-32 (2004). (Pubitemid 38032817)
-
(2004)
Trends in Genetics
, vol.20
, Issue.1
, pp. 23-32
-
-
Ernst, M.1
Jenkins, B.J.2
-
91
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of stat3 in macrophages and neutrophils
-
DOI 10.1016/S1074-7613(00)80005-9
-
K Takeda, BE Clausen, T Kaisho, T Tsujimura, N Terada, I Forster, and S Akira: Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity. 10, 39-49 (1999). (Pubitemid 29077382)
-
(1999)
Immunity
, vol.10
, Issue.1
, pp. 39-49
-
-
Takeda, K.1
Clausen, B.E.2
Kaisho, T.3
Tsujimura, T.4
Terada, N.5
Forster, I.6
Akira, S.7
-
92
-
-
10744223693
-
SOCS3 Is a Critical Physiological Negative Regulator of G-CSF Signaling and Emergency Granulopoiesis
-
DOI 10.1016/S1074-7613(04)00022-6
-
BA Croker, D Metcalf, L Robb, W Wei, S Mifsud, L DiRago, LA Cluse, KD Sutherland, L Hartley, E Williams, JG Zhang, DJ Hilton, NA Nicola, WS Alexander, and AW Roberts: SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. Immunity 20, 153-165 (2004). (Pubitemid 38258392)
-
(2004)
Immunity
, vol.20
, Issue.2
, pp. 153-165
-
-
Croker, B.A.1
Metcalf, D.2
Robb, L.3
Wei, W.4
Mifsud, S.5
DiRago, L.6
Cluse, L.A.7
Sutherland, K.D.8
Hartley, L.9
Williams, E.10
Zhang, J.-G.11
Hilton, D.J.12
Nicola, N.A.13
Alexander, W.S.14
Roberts, A.W.15
-
93
-
-
65449123540
-
Involvement of SOCS3 in regulation of CD11c+ dendritic cell-derived osteoclastogenesis and severe alveolar bone loss
-
X Zhang, M Alnaeeli, B Singh, and YT Teng: Involvement of SOCS3 in regulation of CD11c+ dendritic cell-derived osteoclastogenesis and severe alveolar bone loss. Infect. Immun. 77, 2000-2009 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 2000-2009
-
-
Zhang, X.1
Alnaeeli, M.2
Singh, B.3
Teng, Y.T.4
-
94
-
-
44449140105
-
Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo
-
Y Liu, KN Stewart, E Bishop, CJ Marek, DC Kluth, AJ Rees, and HM Wilson: Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J Immunol 180, 6270- 6278 (2008).
-
(2008)
J Immunol
, vol.180
, pp. 6270-6278
-
-
Liu, Y.1
Stewart, K.N.2
Bishop, E.3
Marek, C.J.4
Kluth, D.C.5
Rees, A.J.6
Wilson, H.M.7
-
95
-
-
70349675421
-
SOCS2 influences LPS induced human monocytederived dendritic cell maturation
-
J Hu, O Winqvist, A Flores-Morales, AC Wikstrom, and G Norstedt: SOCS2 influences LPS induced human monocytederived dendritic cell maturation. PLoS One. 4, e7178 (2009).
-
(2009)
PLoS One
, vol.4
-
-
Hu, J.1
Winqvist, O.2
Flores-Morales, A.3
Wikstrom, A.C.4
Norstedt, G.5
-
96
-
-
0034647541
-
Regulation of SOCS-1 expression by translational repression
-
DOI 10.1074/jbc.M910087199
-
A Gregorieff, S Pyronnet, N Sonenberg, and A Veillette: Regulation of suppressor of cytokine signalling-1 (SOCS-1) expression by translational repression. J. Biol. Chem. 275, 21596-21604 (2000). (Pubitemid 30481866)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.28
, pp. 21596-21604
-
-
Gregorieff, A.1
Pyronnet, S.2
Sonenberg, N.3
Veillette, A.4
-
97
-
-
0037462645
-
The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6
-
DOI 10.1074/jbc.C200608200
-
A Sasaki, K Inagaki-Ohara, T Yoshida, A Yamanaka, M Sasaki, H Yasukawa, AE Koromilas, and A Yoshimura: The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6. J. Biol. Chem. 278, 2432-2436 (2002). (Pubitemid 36801318)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.4
, pp. 2432-2436
-
-
Sasaki, A.1
Inagaki-Ohara, K.2
Yoshida, T.3
Yamanaka, A.4
Sasaki, M.5
Yasukawa, H.6
Koromilas, A.E.7
Yoshimura, A.8
-
98
-
-
0347991978
-
Sepsis-induced SOCS-3 expression is immunologically restricted to phagocytes
-
DOI 10.1189/jlb.0303108
-
PS Grutkoski, Y Chen, CS Chung, and A Ayala: Sepsisinduced SOCS-3 expression is immunologically restricted to phagocytes. J Leukoc. Biol. 74, 916-922 (2003). (Pubitemid 38040368)
-
(2003)
Journal of Leukocyte Biology
, vol.74
, Issue.5
, pp. 916-922
-
-
Grutkoski, P.S.1
Chen, Y.2
Chung, C.S.3
Ayala, A.4
-
99
-
-
0042970542
-
Triggering of toll-like receptors modulates IFN signalling: Involvement of serine 727 STAT1 phosphorylation and suppressors of cytokine signaling
-
DOI 10.1002/eji.200323621
-
AH Dalpke, S Eckerle, M Frey, and K Heeg: Triggering of Toll-like receptors modulates IFN-gamma signaling: involvement of serine 727 STAT1 phosphorylation and suppressors of cytokine signaling. Eur. J. Immunol. 33, 1776-1787 (2003). (Pubitemid 37120848)
-
(2003)
European Journal of Immunology
, vol.33
, Issue.7
, pp. 1776-1787
-
-
Dalpke, A.H.1
Eckerle, S.2
Frey, M.3
Heeg, K.4
-
100
-
-
71649101015
-
Tumor necrosis factor - A augments lipopolysaccharide-induced suppressor of cytokine signalling 3 (SOCS-3) protein expression by preventing the degradation
-
J Dagvadorj, Y Naiki, G Tumurkhuu, AS Noman, Iftakhar-E-Khuda, T Komatsu, N Koide, T Yoshida, and Y Takashi: Tumor necrosis factor-a augments lipopolysaccharide-induced suppressor of cytokine signalling 3 (SOCS-3) protein expression by preventing the degradation. Immunology 129, 97-104 (2010).
-
(2010)
Immunology
, vol.129
, pp. 97-104
-
-
Dagvadorj, J.1
Naiki, Y.2
Tumurkhuu, G.3
Noman, A.S.4
Iftakhar-E-khuda5
Komatsu, T.6
Koide, N.7
Yoshida, T.8
Takashi, Y.9
-
101
-
-
0034234797
-
Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: Partial role of autocrine/paracrine interferon-α/β
-
DOI 10.1042/0264-6021:3490099
-
A Crespo, MB Filla, SW Russell, and WJ Murphy: Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: partial role of autocrine/paracrine interferon-alpha/beta. Biochem. J. 349, 99-104 (2000). (Pubitemid 30440170)
-
(2000)
Biochemical Journal
, vol.349
, Issue.1
, pp. 99-104
-
-
Crespo, A.1
Filla, M.B.2
Russell, S.W.3
Murphy, W.J.4
-
102
-
-
0035168326
-
The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced transcription
-
DOI 10.1515/BC.2001.178
-
JG Bode, S Ludwig, CA Freitas, F Schaper, M Ruhl, S Melmed, PC Heinrich, and D Haussinger: The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced transcription. Biol. Chem. 382, 1447-1453 (2001). (Pubitemid 33062230)
-
(2001)
Biological Chemistry
, vol.382
, Issue.10
, pp. 1447-1453
-
-
Bode, J.G.1
Ludwig, S.2
Correia Freitas, C.A.3
Schaper, F.4
Ruhl, M.5
Melmed, S.6
Heinrich, P.C.7
Haussinger, D.8
-
103
-
-
13244283238
-
Early growth response-1 regulates lipopolysaccharide-induced suppressor of cytokine signaling-1 transcription
-
DOI 10.1074/jbc.M408938200
-
J Mostecki, BM Showalter, and PB Rothman: Early Growth Response-1 Regulates Lipopolysaccharide-induced Suppressor of Cytokine Signaling-1 Transcription. J. Biol. Chem. 280, 2596-2605 (2005). (Pubitemid 40189362)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.4
, pp. 2596-2605
-
-
Mostecki, J.1
Showalter, B.M.2
Rothman, P.B.3
-
104
-
-
38449099334
-
Molecular mechanism of lipopolysaccharide-induced SOCS-3 Gene expression in macrophages and microglia
-
H Qin, KL Roberts, SA Niyongere, Y Cong, CO Elson, and EN Benveniste: Molecular Mechanism of Lipopolysaccharide-Induced SOCS-3 Gene Expression in Macrophages and Microglia. J Immunol 179, 5966-5976 (2007).
-
(2007)
J Immunol
, vol.179
, pp. 5966-5976
-
-
Qin, H.1
Roberts, K.L.2
Niyongere, S.A.3
Cong, Y.4
Elson, C.O.5
Benveniste, E.N.6
-
105
-
-
33847375865
-
MAPK/MK2 cascade
-
C Ehlting, WS Lai, F Schaper, ED Brenndorfer, R-J Matthes, PC Heinrich, S Ludwig, PJ Blackshear, M Gaestel, D Haussinger, and JG Bode: Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-{alpha} Involves Activation of the MKK6/p38MAPK/MK2 Cascade. J Immunol 178, 2813- 2826 (2007). (Pubitemid 46333159)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 2813-2826
-
-
Ehlting, C.1
Lai, W.S.2
Schaper, F.3
Brenndorfer, E.D.4
Matthes, R.-J.5
Heinrich, P.C.6
Ludwig, S.7
Blackshear, P.J.8
Gaestel, M.9
Haussinger, D.10
Bode, J.G.11
-
106
-
-
0037446652
-
Persistence of lesions in suppressor of cytokine signaling-1-deficient mice infected with Leishmania major
-
DVR Bullen, TM Baldwin, JM Curtis, WS Alexander, and E Handman: Persistence of Lesions in Suppressor of Cytokine Signaling-1-Deficient Mice Infected with Leishmania major. J Immunol 170, 4267-4272 (2003). (Pubitemid 36428194)
-
(2003)
Journal of Immunology
, vol.170
, Issue.8
, pp. 4267-4272
-
-
Bullen, D.V.R.1
Baldwin, T.M.2
Curtis, J.M.3
Alexander, W.S.4
Handman, E.5
-
107
-
-
0345073627
-
Leishmania donovani-induced expression of suppressor of cytokine signaling 3 in human macrophages: A novel mechanism for intracellular parasite suppression of activation
-
DOI 10.1128/IAI.71.4.2095-2101.2003
-
S Bertholet, HL Dickensheets, F Sheikh, AA Gam, RP Donnelly, and RT Kenney: Leishmania donovani-Induced Expression of Suppressor of Cytokine Signaling 3 in Human Macrophages: a Novel Mechanism for Intracellular Parasite Suppression of Activation. Infect. Immun. 71, 2095-2101 (2003). (Pubitemid 36368744)
-
(2003)
Infection and Immunity
, vol.71
, Issue.4
, pp. 2095-2101
-
-
Bertholet, S.1
Dickensheets, H.L.2
Sheikh, F.3
Gam, A.A.4
Donnelly, R.P.5
Kenney, R.T.6
-
108
-
-
0242391852
-
Mycobacterium bovis bacillus Calmette-Guérin infection promotes SOCS induction and inhibits IFN-γ-stimulated JAK/STAT signaling in J774 macrophages
-
DOI 10.1016/S0928-8244(03)00231-1
-
K Imai, T Kurita-Ochiai, and K Ochiai: Mycobacterium bovis bacillus Calmette-Guerin infection promotes SOCS induction and inhibits IFN-gammastimulated JAK/STAT signaling in J774 macrophages. FEMS Immunol Med Microbiol. 39, 173-180 (2003). (Pubitemid 37415083)
-
(2003)
FEMS Immunology and Medical Microbiology
, vol.39
, Issue.2
, pp. 173-180
-
-
Imai, K.1
Kurita-Ochiai, T.2
Ochiai, K.3
-
109
-
-
33750490101
-
Mycobacterium avium-induced SOCS contributes to resistance to IFN-γ-mediated mycobactericidal activity in human macrophages
-
DOI 10.1189/jlb.0306206
-
N Vazquez, T Greenwell-Wild, S Rekka, JM Orenstein, and SM Wahl: Mycobacterium avium-induced SOCS contributes to resistance to IFN-{gamma}-mediated mycobactericidal activity in human macrophages. J Leukoc Biol. 80, 1136-1144 (2006). (Pubitemid 44646319)
-
(2006)
Journal of Leukocyte Biology
, vol.80
, Issue.5
, pp. 1136-1144
-
-
Vazquez, N.1
Greenwell-Wild, T.2
Rekka, S.3
Orenstein, J.M.4
Wahl, S.M.5
-
110
-
-
31144437094
-
Induction of suppressor of cytokine signaling-1 by Toxoplasma gondii contributes to immune evasion in macrophages by blocking IFN-γ signaling
-
S Zimmermann, PJ Murray, K Heeg, and AH Dalpke: Induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-{gamma} Signaling. J Immunol 176, 1840-1847 (2006). (Pubitemid 43134329)
-
(2006)
Journal of Immunology
, vol.176
, Issue.3
, pp. 1840-1847
-
-
Zimmermann, S.1
Murray, P.J.2
Heeg, K.3
Dalpke, A.H.4
-
111
-
-
67149099807
-
HIV-1 trans-activator protein induction of suppressor of cytokine signaling-2 contributes to dysregulation of IFN{gamma} signaling
-
SM Cheng, JC Li, SS Lin, DC Lee, L Liu, Z Chen, and AS Lau: HIV-1 trans-activator protein induction of suppressor of cytokine signaling-2 contributes to dysregulation of IFN{gamma} signaling. Blood 113, 5192- 5201 (2009).
-
(2009)
Blood
, vol.113
, pp. 5192-5201
-
-
Cheng, S.M.1
Li, J.C.2
Lin, S.S.3
Lee, D.C.4
Liu, L.5
Chen, Z.6
Lau, A.S.7
-
112
-
-
77956944087
-
Suppressor of cytokine signaling 3 inhibits antiviral IFN-{beta} signaling to enhance HIV-1 replication in macrophages
-
LN Akhtar, H Qin, MT Muldowney, LL Yanagisawa, O Kutsch, JE Clements, and EN Benveniste: Suppressor of Cytokine Signaling 3 Inhibits Antiviral IFN-{beta} Signaling To Enhance HIV-1 Replication in Macrophages. J. Immunol. 185, 2393-2404. (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 2393-2404
-
-
Akhtar, L.N.1
Qin, H.2
Muldowney, M.T.3
Yanagisawa, L.L.4
Kutsch, O.5
Clements, J.E.6
Benveniste, E.N.7
-
113
-
-
67049119148
-
Respiratory syncytial virus proteins modulate suppressors of cytokine signaling 1 and 3 and the type I interferon response to infection by a toll-like receptor pathway
-
CM Oshansky, TM Krunkosky, J Barber, LP Jones, and RA Tripp: Respiratory syncytial virus proteins modulate suppressors of cytokine signaling 1 and 3 and the type I interferon response to infection by a toll-like receptor pathway. Viral Immunol. 22, 147-161 (2009).
-
(2009)
Viral Immunol.
, vol.22
, pp. 147-161
-
-
Oshansky, C.M.1
Krunkosky, T.M.2
Barber, J.3
Jones, L.P.4
Tripp, R.A.5
-
114
-
-
55849145545
-
Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)
-
EC Moore, J Barber, and RA Tripp: Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15). Virol. J 5, 116 (2008).
-
(2008)
Virol. J
, vol.5
, pp. 116
-
-
Moore, E.C.1
Barber, J.2
Tripp, R.A.3
-
115
-
-
68749090768
-
RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules
-
K Hashimoto, K Ishibashi, K Ishioka, D Zhao, M Sato, S Ohara, Y Abe, Y Kawasaki, Y Sato, SI Yokota, N Fujii, RS Peebles Jr., M Hosoya, and T Suzutani: RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules. Virology 391, 162-170 (2009).
-
(2009)
Virology
, vol.391
, pp. 162-170
-
-
Hashimoto, K.1
Ishibashi, K.2
Ishioka, K.3
Zhao, D.4
Sato, M.5
Ohara, S.6
Abe, Y.7
Kawasaki, Y.8
Sato, Y.9
Yokota, S.I.10
Fujii, N.11
Peebles Jr., R.S.12
Hosoya, M.13
Suzutani, T.14
-
116
-
-
44849105646
-
SOCS-1 protects against chlamydia pneumoniae-induced lethal inflammation but hampers effective bacterial clearance
-
T Yang, P Stark, K Janik, H Wigzell, and ME Rottenberg: SOCS-1 Protects against Chlamydia pneumoniae-Induced Lethal Inflammation but Hampers Effective Bacterial Clearance. J Immunol 180, 4040-4049 (2008).
-
(2008)
J Immunol
, vol.180
, pp. 4040-4049
-
-
Yang, T.1
Stark, P.2
Janik, K.3
Wigzell, H.4
Rottenberg, M.E.5
-
117
-
-
59649114146
-
CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression
-
NJ Stevenson, MR Addley, EJ Ryan, CR Boyd, HP Carroll, V Paunovic, CA Bursill, HC Miller, KM Channon, AE McClurg, MA Armstrong, WA Coulter, DR Greaves, and JA Johnston: CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression. J Leukoc Biol 85, 289-297 (2009).
-
(2009)
J Leukoc Biol
, vol.85
, pp. 289-297
-
-
Stevenson, N.J.1
Addley, M.R.2
Ryan, E.J.3
Boyd, C.R.4
Carroll, H.P.5
Paunovic, V.6
Bursill, C.A.7
Miller, H.C.8
Channon, K.M.9
McClurg, A.E.10
Armstrong, M.A.11
Coulter, W.A.12
Greaves, D.R.13
Johnston, J.A.14
-
118
-
-
70349650125
-
Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domaincontaining adapter inducing IFN-{beta}-dependent pathways and increases expression of negative regulators of TLR signaling
-
J
-
W Piao, C Song, H Chen, MA Quevedo Diaz, LM Wahl, KA Fitzgerald, L Li, and AE Medvedev: Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domaincontaining adapter inducing IFN-{beta}-dependent pathways and increases expression of negative regulators of TLR signaling. J. Leukoc. Biol 86, 863-875 (2009).
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 863-875
-
-
Piao, W.1
Song, C.2
Chen, H.3
Diaz, M.A.Q.4
Wahl, L.M.5
Fitzgerald, K.A.6
Li, L.7
Medvedev, A.E.8
-
119
-
-
74549130435
-
CD14 signaling restrains chronic inflammation through Induction of p38-MAPK/SOCS dependent tolerance
-
B Sahay, RL Patsey, CH Eggers, JC Salazar, JD Radolf, and TJ Sellati: CD14 Signaling Restrains Chronic Inflammation through Induction of p38-MAPK/SOCSDependent Tolerance. PLoS Pathog. 5, e1000687 (2009).
-
(2009)
PLoS Pathog
, vol.5
-
-
Sahay, B.1
Patsey, R.L.2
Eggers, C.H.3
Salazar, J.C.4
Radolf, J.D.5
Sellati, T.J.6
-
120
-
-
33750037600
-
Contribution of interferon-β to the murine macrophage response to the toll-like receptor 4 agonist, lipopolysaccharide
-
DOI 10.1074/jbc.M604958200
-
KE Thomas, CL Galligan, NR Deonarain, EN Fish, and SN Vogel: Contribution of interferon (IFN)-beta to the murine macrophage response to the TLR4 agonist, lipopolysaccharide. J Biol Chem. 281, 31119-31130 (2006). (Pubitemid 44582166)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.41
, pp. 31119-31130
-
-
Thomas, K.E.1
Galligan, C.L.2
Newman, R.D.3
Fish, E.N.4
Vogel, S.N.5
-
121
-
-
0038476601
-
Central role for type I interferons and Tyk2 in lipopolysaccharide- induced endotoxin shock
-
DOI 10.1038/ni910
-
M Karaghiosoff, R Steinborn, P Kovarik, G Kriegshauser, M Baccarini, B Donabauer, U Reichart, T Kolbe, C Bogdan, T Leanderson, D Levy, T Decker, and M Muller: Central role for type I interferons and Tyk2 in lipopolysaccharide- induced endotoxin shock. Nat. Immunol 4, 471-477 (2003). (Pubitemid 36592440)
-
(2003)
Nature Immunology
, vol.4
, Issue.5
, pp. 471-477
-
-
Karaghiosoff, M.1
Steinborn, R.2
Kovarik, P.3
Kriegshauser, G.4
Baccarin, M.5
Donabauer, B.6
Reichart, U.7
Kolbe, T.8
Bogdan, C.9
Leanderson, T.10
Levy, D.11
Decker, T.12
Muller, M.13
-
122
-
-
35748939086
-
Differential Effects of CpG DNA on IFN-beta Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages
-
K Schroder, M Spille, A Pilz, J Lattin, KA Bode, KM Irvine, AD Burrows, T Ravasi, H Weighardt, KJ Stacey, T Decker, DA Hume, AH Dalpke, and MJ Sweet: Differential Effects of CpG DNA on IFN-beta Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages. J Immunol 179, 3495-3503 (2007).
-
(2007)
J Immunol
, vol.179
, pp. 3495-3503
-
-
Schroder, K.1
Spille, M.2
Pilz, A.3
Lattin, J.4
Bode, K.A.5
Irvine, K.M.6
Burrows, A.D.7
Ravasi, T.8
Weighardt, H.9
Stacey, K.J.10
Decker, T.11
Hume, D.A.12
Dalpke, A.H.13
Sweet, M.J.14
-
123
-
-
79959355521
-
Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptorinduced STAT1 activation
-
doi/10.1073/pnas.1017296108
-
S Bhattacharyya, Y Zhao, TW Kay, and LJ Muglia: Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptorinduced STAT1 activation. Proc. Natl. Acad. Sci. U. S. A doi/10.1073/pnas.1017296108, (2011).
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
-
-
Bhattacharyya, S.1
Zhao, Y.2
Kay, T.W.3
Muglia, L.J.4
-
124
-
-
28044461950
-
Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT
-
DOI 10.1073/pnas.0508517102
-
A Kimura, T Naka, T Muta, O Takeuchi, S Akira, I Kawase, and T Kishimoto: Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT. PNAS 102, 17089-17094 (2005). (Pubitemid 41692688)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.47
, pp. 17089-17094
-
-
Kimura, A.1
Naka, T.2
Muta, T.3
Takeuchi, O.4
Akira, S.5
Kawase, I.6
Kishimoto, T.7
-
125
-
-
33646836481
-
SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation
-
DOI 10.1074/jbc.M512338200
-
Y He, W Zhang, R Zhang, H Zhang, and W Min: SOCS1 Inhibits Tumor Necrosis Factor-induced Activation of ASK1- JNK Inflammatory Signaling by Mediating ASK1 Degradation. J. Biol. Chem. 281, 5559-5566 (2006). (Pubitemid 43847652)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.9
, pp. 5559-5566
-
-
He, Y.1
Zhang, W.2
Zhang, R.3
Zhang, H.4
Min, W.5
-
126
-
-
31344467156
-
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
-
DOI 10.1038/ni1299, PII N1299
-
A Mansell, R Smith, SL Doyle, P Gray, JE Fenner, PJ Crack, SE Nicholson, DJ Hilton, LA O'Neill, and PJ Hertzog: Suppressor of cytokine signaling 1 negatively regulates Tolllike receptor signaling by mediating Mal degradation. Nat. Immunol. 7, 148-155 (2006). (Pubitemid 43135880)
-
(2006)
Nature Immunology
, vol.7
, Issue.2
, pp. 148-155
-
-
Mansell, A.1
Smith, R.2
Doyle, S.L.3
Gray, P.4
Fenner, J.E.5
Crack, P.J.6
Nicholson, S.E.7
Hilton, D.J.8
O'Neill, L.A.J.9
Luke, A.J.10
Hertzog, P.J.11
-
127
-
-
33644831336
-
4 and aspirin-triggered lipoxin are SOCS-2 dependent
-
DOI 10.1038/nm1355, PII N1355
-
FS Machado, JE Johndrow, L Esper, A Dias, A Bafica, CN Serhan, and J Aliberti: Anti-inflammatory actions of lipoxin A(4) and aspirin-triggered lipoxin are SOCS-2 dependent. Nat. Med. 12, 330-334 (2006). (Pubitemid 43355082)
-
(2006)
Nature Medicine
, vol.12
, Issue.3
, pp. 330-334
-
-
Machado, F.S.1
Johndrow, J.E.2
Esper, L.3
Dias, A.4
Bafica, A.5
Serhan, C.N.6
Aliberti, J.7
-
128
-
-
43549114554
-
Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6
-
DOI 10.1084/jem.20072416
-
FS Machado, L Esper, A Dias, R Madan, Y Gu, D Hildeman, CN Serhan, CL Karp, and J Aliberti: Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6. J. Exp. Med. 205, 1077-1086 (2008). (Pubitemid 351679683)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.5
, pp. 1077-1086
-
-
Machado, F.S.1
Esper, L.2
Dias, A.3
Madan, R.4
Gu, Y.5
Hildeman, D.6
Serhan, C.N.7
Karp, C.L.8
Aliberti, J.9
-
130
-
-
0027176524
-
Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κb
-
DOI 10.1038/365182a0
-
T Henkel, T Machleidt, I Alkalay, M Kronke, Y Ben-Neriah, and PA
-
(1993)
Nature
, vol.365
, Issue.6442
, pp. 182-185
-
-
Henkel, T.1
Machleidt, T.2
Alkalay, I.3
Kronke, M.4
Ben-Neriah, Y.5
Baeuerle, P.A.6
-
131
-
-
3142771914
-
Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor κB response
-
DOI 10.1084/jem.20040196
-
S Saccani, I Marazzi, AA Beg, and G Natoli: Degradation of Promoter-bound p65/RelA Is Essential for the Prompt Termination of the Nuclear Factor {kappa}B Response. J. Exp. Med. 200, 107-113 (2004). (Pubitemid 38924733)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.1
, pp. 107-113
-
-
Saccani, S.1
Marazzi, I.2
Beg, A.A.3
Natoli, G.4
-
132
-
-
45149090556
-
Nuclear ubiquitin ligases, NFκB degradation, and the control of inflammation
-
G Natoli, and S Chiocca: Nuclear Ubiquitin Ligases, NFκB Degradation, and the Control of Inflammation. Science Signaling 1, e1 (2008).
-
(2008)
Science Signaling
, vol.1
-
-
Natoli, G.1
Chiocca, S.2
-
133
-
-
34249066486
-
PDLIM2-mediated termination of transcription factor NF-κB activation by intranuclear sequestration and degradation of the p65 subunit
-
DOI 10.1038/ni1464, PII NI1464
-
T Tanaka, MJ Grusby, and T Kaisho: PDLIM2- mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit. Nat Immunol 8, 584-591 (2007). (Pubitemid 46785122)
-
(2007)
Nature Immunology
, vol.8
, Issue.6
, pp. 584-591
-
-
Tanaka, T.1
Grusby, M.J.2
Kaisho, T.3
-
134
-
-
77949540609
-
Pim-1 controls NF-kappaB signalling by stabilizing RelA/p65
-
K Nihira, Y Ando, T Yamaguchi, Y Kagami, Y Miki, and K Yoshida: Pim-1 controls NF-kappaB signalling by stabilizing RelA/p65. Cell Death. Differ. 17, 689-698 (2009).
-
(2009)
Cell Death. Differ.
, vol.17
, pp. 689-698
-
-
Nihira, K.1
Ando, Y.2
Yamaguchi, T.3
Kagami, Y.4
Miki, Y.5
Yoshida, K.6
-
135
-
-
0035908126
-
Two waves of nuclear factor κb recruitment to target promoters
-
S Saccani, S Pantano, and G Natoli: Two Waves of Nuclear Factor κB Recruitment to Target Promoters. J Exp Med 193, 1351-1360 (2001).
-
(2001)
J Exp Med
, vol.193
, pp. 1351-1360
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
136
-
-
34447520614
-
UXT is a novel and essential cofactor in the NF-κB transcriptional enhanceosome
-
DOI 10.1083/jcb.200611081
-
S Sun, Y Tang, X Lou, L Zhu, K Yang, B Zhang, H Shi, and C Wang: UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome. J. Cell Biol 178, 231-244 (2007). (Pubitemid 47076460)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.2
, pp. 231-244
-
-
Sun, S.1
Tang, Y.2
Lou, X.3
Zhu, L.4
Yang, K.5
Zhang, B.6
Shi, H.7
Wang, C.8
-
137
-
-
0033558088
-
Socs1 binds to multiple signalling proteins and suppresses Steel factor-dependent proliferation
-
DOI 10.1093/emboj/18.4.904
-
P De Sepulveda, K Okkenhaug, JL Rose, RG Hawley, P Dubreuil, and R Rottapel: Socs1 binds to multiple signalling proteins and suppresses steel factor- dependent proliferation. EMBO J. 18, 904-915 (1999). (Pubitemid 29082270)
-
(1999)
EMBO Journal
, vol.18
, Issue.4
, pp. 904-915
-
-
De Sepulveda, P.1
Okkenhaug, K.2
La Rose, J.3
Hawley, R.G.4
Dubreuil, P.5
Rottapel, R.6
-
138
-
-
65649128907
-
Termination of NFkappaB activity through a gammaherpesvirus protein that assembles an EC(5)S ubiquitin-ligase
-
L Rodrigues, J Filipe, MP Seldon, L Fonseca, J Anrather, MP Soares, and JP Simas: Termination of NFkappaB activity through a gammaherpesvirus protein that assembles an EC(5)S ubiquitin-ligase. EMBO J. 28, 1283- 1295 (2009).
-
(2009)
EMBO J
, vol.28
, pp. 1283-1295
-
-
Rodrigues, L.1
Filipe, J.2
Seldon, M.P.3
Fonseca, L.4
Anrather, J.5
Soares, M.P.6
Simas, J.P.7
-
139
-
-
61449254342
-
Kinetic of RelA activation controls magnitude of TLR-mediated IL-12p40 induction
-
KA Bode, F Schmitz, L Vargas, K Heeg, and AH Dalpke: Kinetic of RelA activation controls magnitude of TLR-mediated IL-12p40 induction. J. Immunol. 182, 2176- 2184 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 2176-2184
-
-
Bode, K.A.1
Schmitz, F.2
Vargas, L.3
Heeg, K.4
Dalpke, A.H.5
|