Suppressor of cytokine signaling 3 inhibits antiviral IFN-β signaling to enhance HIV-1 replication in macrophages

Journal of Immunology

Volumn 185, Issue 4, 2010, Pages 2393-2404

  Akhtar, Lisa Nowoslawski ^a   Qin, Hongwei ^a   Muldowney, Michelle T ^a   Yanagisawa, Lora L ^a   Kutsch, Olaf ^b   Clements, Janice E ^c   Benveniste, Etty N ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; ANTIVIRUS AGENT; PEPTIDE FRAGMENT; SOCS3 PROTEIN, HUMAN; SOCS3 PROTEIN, MOUSE; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM INFECTION; DISEASE COURSE; DISEASE SEVERITY; GENE EXPRESSION; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS INHIBITION; VIRUS LOAD; VIRUS REPLICATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CHEMISTRY; DRUG EFFECT; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MACACA; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIROLOGY;

AIDS DEMENTIA COMPLEX; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELLS, CULTURED; GENE EXPRESSION; HIV INFECTIONS; HIV-1; HUMANS; INTERFERON-BETA; MACACA MULATTA; MACROPHAGES; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; STAT TRANSCRIPTION FACTORS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

EID: 77956944087     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903563     Document Type: Article

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