Two waves of nuclear factor κB recruitment to target promoters

Journal of Experimental Medicine

Volumn 193, Issue 12, 2001, Pages 1351-1359

  Saccani, Simona ^a   Pantano, Serafino ^a   Natoli, Gioacchino ^a  

^a V V Vela   (Switzerland)

Author keywords

Chromatin immunoprecipitation; Histone acetylation; Lipopolysaccharide; NF B; Rel

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANIMAL CELL; ARTICLE; BIOMEDICINE; CHROMATIN STRUCTURE; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

ACETYLATION; ANIMALS; BINDING SITES; CELL LINE; CELL NUCLEUS; CHROMATIN; DNA-BINDING PROTEINS; HISTONES; I-KAPPA B PROTEINS; KINETICS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN TRANSPORT;

EID: 0035908126     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.12.1351     Document Type: Article

References (47)

1. The NF-kappa B and I kappa B proteins: New discoveries and insights
2. NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
3. I kappa B: A specific inhibitor of the NF-kappa B transcription factor
4. Rel-associated pp40: An inhibitor of the rel family of transcription factors
5. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity
6. I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B
7. I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity
8. I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: A mechanism for cytoplasmic retention
9. I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding
10. The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding
11. Nuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleus
12. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: A mechanism for NF-kappa B activation
13. Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B
14. The transcription factor NF-kappaB: Control of oncogenesis and cancer therapy resistance
15. Purified human I kappa B can rapidly dissociate the complex of the NF- kappa B transcription factor with its cognate DNA
16. Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B
17. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
18. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
19. Identification and characterization of an IkappaB kinase
20. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
21. IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
22. IKK-1 and IKK-2: Cytokine-activated IkappaB kinases essential for NF-kappaB activation
23. Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
24. The IKK complex: An integrator of all signals that activate NF-kappaB?
25. Identification of the receptor component of the IkappaBalpha-ubiquitin ligase
26. A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways
27. Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction
28. A critical role for the RelA subunit of nuclear factor kappaB in regulation of multiple immune-response genes and in Fas-induced cell death
29. Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB
30. Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B
31. Activation of the human RANTES gene promoter in a macrophage cell line by lipopolysaccharide is dependent on stress-activated protein kinases and the IkappaB kinase cascade: Implications for exacerbation of allergic inflammation by environmental pollutants
32. Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: The dominant role for NF-kappaB but not C/EBPss or c-Jun
33. TNF regulates the m vivo occupancy of both distal and proximal regulatory regions of the MCP-1/JE gene
34. NF-kappa B and Rel: Participants in a multiform transcriptional regulatory system
35. What does ́chromatin remodelinǵ mean?
36. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
37. Histone acetylation in chromatin structure and transcription
38. Acetylation and chromosomal functions
39. The language of covalent histone modifications
40. Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription
41. Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter
42. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter
43. Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription
44. Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages
45. Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event
46. Chromatin condensation: Does histone H1 dephosphorylation play a role?
47. Prolonged glucocorticoid exposure dephosphorylates histone H1 and inactivates the MMTV promoter