The SOCS Box of SOCS-1 Accelerates Ubiquitin-dependent Proteolysis of TEL-JAK2

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 12530-12538

  Kamizono, Shintaro ^a   Hanada, Toshikatsu ^a   Yasukawa, Hideo ^a   Minoguchi, Shigeru ^a   Kato, Reiko ^a   Minoguchi, Mayu ^a   Hattori, Kimihiko ^b   Hatakeyama, Shigetsugu ^b   Yada, Masayoshi ^b   Morita, Sumiyo ^c   Kitamura, Toshio ^c   Kato, Hirohisa ^a   Nakayama, Kei Ichi ^b   Yoshimura, Akihiko ^a,b  

^a KURUME UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGENS; CELL CULTURE; CHEMICAL ACTIVATION; ENZYME INHIBITION; GENETIC ENGINEERING; TUMORS;

PHOSPHORYLATION;

BIOCHEMISTRY;

CULLIN 2; CYTOKINE; ELONGIN B; ELONGIN C; GENE PRODUCT; JAK2 TYROSINE KINASE; JANUS KINASE; PHOSPHOTRANSFERASE INHIBITOR; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CARRIER PROTEIN; CELL CYCLE PROTEIN; CUL2 PROTEIN, HUMAN; CULLIN; ELONGIN; HYBRID PROTEIN; ONCOPROTEIN; RECOMBINANT PROTEIN; REPRESSOR PROTEIN; SIGNAL PEPTIDE; SOCS1 PROTEIN, HUMAN; SOCS1 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING; TEL JAK2 FUSION PROTEIN, HUMAN; TEL JAK2 FUSION PROTEIN, MOUSE; TEL-JAK2 FUSION PROTEIN, HUMAN; TEL-JAK2 FUSION PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; CHROMOSOME 12P; CHROMOSOME 9P; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FUSION GENE; GENE; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE OVEREXPRESSION; HOMEOBOX; LEUKEMIA; MOUSE; NONHUMAN; OLIGOMERIZATION; ONCOGENE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SOCS 1 GENE; SOCS BOX; TEL JAK2 FUSION GENE; TUMOR SUPPRESSOR GENE; VON HIPPEL LINDAU DISEASE; ANIMAL; BINDING SITE; CELL DIVISION; CELL LINE; CHEMISTRY; CHROMOSOME 12; CHROMOSOME 9; GENETIC TRANSFECTION; GENETICS; HUMAN; KINETICS; METABOLISM; MUTAGENESIS; PHOSPHORYLATION; SRC HOMOLOGY DOMAIN;

ANIMALIA; JANUS;

ANIMALS; BINDING SITES; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 9; CULLIN PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; LEUKEMIA; MICE; MUTAGENESIS; ONCOGENE PROTEINS, FUSION; PHOSPHORYLATION; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SRC HOMOLOGY DOMAINS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION FACTORS; TRANSFECTION; UBIQUITINS;

EID: 0035918239     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010074200     Document Type: Article

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