Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)

Virology Journal

Volumn 5, Issue , 2008, Pages

  Moore, Elizabeth C ^a   Barber, Jamie ^a   Tripp, Ralph A ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERFERON; INTERFERON STIMULATED GENE FACTOR 15; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; CYTOKINE; ISG15 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING; UBIQUITIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BRONCHIOLE; CELL LINE; CELL STRAIN MLE-I 5; CELL TYPE; EPITHELIUM CELL; GENE DELETION; IMMUNE RESPONSE; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; MOUSE; MUTANT; NONHUMAN; PROTEIN EXPRESSION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS INFECTION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; PHYSIOLOGY; VIROLOGY; VIRUS ATTACHMENT;

ANIMALIA; MUS; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

ANIMALS; CELL LINE; CYTOKINES; EPITHELIAL CELLS; GENE DELETION; GENE EXPRESSION PROFILING; INTERFERON TYPE I; MICE; RESPIRATORY SYNCYTIAL VIRUSES; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; UBIQUITINS; VIRAL NONSTRUCTURAL PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRUS ATTACHMENT;

EID: 55849145545     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-5-116     Document Type: Article

References (69)

1. The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: friend or foe? JB Andersen BA Hassel, Cytokine Growth Factor Rev 2006 17 6 411 21 10.1016/j.cytogfr.2006.10.001 17097911
2. Respiratory syncytial virus (RSV) evades the human adaptive immune system by skewing the Th1/Th2 cytokine balance toward increased levels of Th2 cytokines and IgE, markers of allergy - a review. Y Becker, Virus Genes 2006 33 2 235 52 16972040
3. Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-kappaB-dependent, interferon-independent mechanism and facilitate virus growth. V Bitko O Shulyayeva B Mazumder A Musiyenko M Ramaswamy DC Look S Barik, J Virol 2007 81 4 1786 95 17151097 10.1128/JVI.01420-06
4. Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3. B Bossert S Marozin KK Conzelmann, J Virol 2003 77 16 8661 8 12885884 10.1128/JVI.77.16.8661-8668.2003
5. Nucleotide sequences of the 1B and 1C nonstructural protein mRNAs of human respiratory syncytial virus. PL Collins GW Wertz, Virology 1985 143 2 442 51 10.1016/0042-6822(85)90384-8 2998021
6. Host responses to respiratory virus infection and immunization. JE Crowe Jr, Curr Top Microbiol Immunol 1999 236 191 214 9893361
7. Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins. A Dalpke K Heeg H Bartz A Baetz, Immunobiology 2008 213 3-4 225 35 10.1016/j.imbio.2007.10.008 18406369
8. Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection. A Didierlaurent J Goulding S Patel R Snelgrove L Low M Bebien T Lawrence LS van Rijt BN Lambrecht JC Sirard T Hussell, J Exp Med 2008 205 2 323 9 18227219 10.1084/jem.20070891
9. Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway. Z Du L Wei A Murti SR Pfeffer M Fan CH Yang LM Pfeffer, J Cell Biochem 2007 102 5 1087 94 10.1002/jcb.21535 17910035
10. Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase. J Elliott OT Lynch Y Suessmuth P Qian CR Boyd JF Burrows R Buick NJ Stevenson O Touzelet M Gadina UF Power JA Johnston, J Virol 2007 81 7 3428 36 17251292 10.1128/JVI.02303-06
11. Expression and characterisation of the NS1 and NS2 proteins of respiratory syncytial virus. JE Evans PA Cane CR Pringle, Virus Res 1996 43 2 155 61 10.1016/0168-1702(96)01327-5 8864205
12. Respiratory syncytial virus infection in adults. AR Falsey, Semin Respir Crit Care Med 2007 28 2 171 81 10.1055/s-2007-976489 17458771
13. Function of the respiratory syncytial virus small hydrophobic protein. S Fuentes KC Tran P Luthra MN Teng B He, J Virol 2007 81 15 8361 6 17494063 10.1128/JVI.02717-06
14. Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. NV Giannakopoulos JK Luo V Papov W Zou DJ Lenschow BS Jacobs EC Borden J Li HW Virgin DE Zhang, Biochem Biophys Res Commun 2005 336 2 496 506 10.1016/j.bbrc.2005.08.132 16139798
15. Paramyxovirus accessory proteins as interferon antagonists. B Gotoh T Komatsu K Takeuchi J Yokoo, Microbiol Immunol 2001 45 12 787 800 11838896
16. Respiratory syncytial virus G protein and G protein CX3C motif adversely affect CX3CR1+ T cell responses. J Harcourt R Alvarez LP Jones C Henderson LJ Anderson RA Tripp, J Immunol 2006 176 3 1600 8 16424189
17. Anti-G protein antibody responses to respiratory syncytial virus infection or vaccination are associated with inhibition of G protein CX3C-CX3CR1 binding and leukocyte chemotaxis. JL Harcourt RA Karron RA Tripp, J Infect Dis 2004 190 11 1936 40 10.1086/425516 15529257
18. Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus. LM Haynes DD Moore EA Kurt-Jones RW Finberg LJ Anderson RA Tripp, J Virol 2001 75 22 10730 7 11602714 10.1128/JVI.75.22.10730-10737.2001
19. Pathogenesis of respiratory syncytial virus infection in ferret and fetal human tracheas in organ culture. FW Henderson SC Hu AM Collier, Am Rev Respir Dis 1978 118 1 29 37 354444
20. IRF-7 is the master regulator of type-I interferon-dependent immune responses. K Honda H Yanai H Negishi M Asagiri M Sato T Mizutani N Shimada Y Ohba A Takaoka N Yoshida T Taniguchi, Nature 2005 434 7034 772 7 10.1038/nature03464 15800576
21. Ikkepsilon regulates viral-induced interferon regulatory factor-3 activation via a redox-sensitive pathway. H Indukuri SM Castro SM Liao LA Feeney M Dorsch AJ Coyle RP Garofalo AR Brasier A Casola, Virology 2006 353 1 155 65 10.1016/j.virol.2006.05.022 16806387
22. Respiratory viral infections in transplant recipients. MG Ison, Antivir Ther 2007 12 4 Pt B 627 38 17944270
23. Different patterns of cytokine induction in cultures of respiratory syncytial (RS) virus-specific human TH cell lines following stimulation with RS virus and RS virus proteins. M Jackson R Scott, J Med Virol 1996 49 3 161 9 10.1002/(SICI)1096-9071(199607)49:3<161::AID-JMV2>3.0.CO;2-2 8818960
24. SOCS: physiological suppressors of cytokine signaling. DL Krebs DJ Hilton, J Cell Sci 2000 113 Pt 16 2813 9 10910765
25. Suppressor of cytokine signaling 3 (SOCS3) in Th2 cells evokes Th2 cytokines, IgE, and eosinophilia. M Kubo H Inoue, Curr Allergy Asthma Rep 2006 6 1 32 9 10.1007/s11882-006-0007-6 16476192
26. Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression. T Kubota M Matsuoka TH Chang P Tailor T Sasaki M Tashiro A Kato K Ozato, J Biol Chem 2008
27. Interferon targeted genes in host defense. MS Kunzi PM Pitha, Autoimmunity 2003 36 8 457 61 10.1080/08916930310001605855 14984022
28. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. EA Kurt-Jones L Popova L Kwinn LM Haynes LP Jones RA Tripp EE Walsh MW Freeman DT Golenbock LJ Anderson RW Finberg, Nat Immunol 2000 1 5 398 401 10.1038/80833 11062499
29. Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness. MS Lo RM Brazas MJ Holtzman, J Virol 2005 79 14 9315 9 15994826 10.1128/JVI.79.14. 9315-9319.2005
30. ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation. G Lu JT Reinert I Pitha-Rowe A Okumura M Kellum KP Knobeloch B Hassel PM Pitha, Cell Mol Biol (Noisy-le-grand) 2006 52 1 29 41 16914094
31. Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections? S Mahalingam J Schwarze A Zaid M Nissen T Sloots S Tauro J Storer R Alvarez RA Tripp, Microbes Infect 2006 8 1 285 93 10.1016/j.micinf.2005.07.001 16182587
32. High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction. MP Malakhov KI Kim OA Malakhova BS Jacobs EC Borden DE Zhang, J Biol Chem 2003 278 19 16608 13 10.1074/jbc.M208435200 12582176
33. Respiratory syncytial virus infection in adults. Y Murata AR Falsey, Antivir Ther 2007 12 4 Pt B 659 70 17944273
34. Laminin alpha-chain expression and basement membrane formation by MLE-15 respiratory epithelial cells. NM Nguyen Y Bai K Mochitate RM Senior, Am J Physiol Lung Cell Mol Physiol 2002 282 5 L1004 11 11943665
35. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. LA O'Neill AG Bowie, Nat Rev Immunol 2007 7 5 353 64 10.1038/nri2079 17457343
36. Pathogenesis of respiratory syncytial virus infection in the murine model. RS Peebles Jr BS Graham, Proc Am Thorac Soc 2005 2 2 110 5 10.1513/pats.200501-002AW 16113477
37. Morphologic changes reflecting early and late effects of irradiation of the distal lung of the mouse: a review. DP Penney DW Siemann P Rubin DL Shapiro J Finkelstein RA Cooper Jr, Scan Electron Microsc 1982 Pt 1 413 25 7167757
38. Viral defense, carcinogenesis and ISG15: novel roles for an old ISG. IF Pitha-Rowe PM Pitha, Cytokine Growth Factor Rev 2007 18 5-6 409 17 17689132 10.1016/j.cytogfr.2007.06.017
39. TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease. B Puthothu J Forster A Heinzmann M Krueger, Dis Markers 2006 22 5-6 303 8 17264400
40. Specific inhibition of type I interferon signal transduction by respiratory syncytial virus. M Ramaswamy L Shi MM Monick GW Hunninghake DC Look, Am J Respir Cell Mol Biol 2004 30 6 893 900 10.1165/rcmb.2003-0410OC 14722224
41. ISG15: the immunological kin of ubiquitin. KJ Ritchie DE Zhang, Semin Cell Dev Biol 2004 15 2 237 46 10.1016/j.semcdb.2003.12.005 15209384
42. Interferon-inducible antiviral effectors. AJ Sadler BR Williams, Nat Rev Immunol 2008 8 7 559 68 10.1038/nri2314 18575461
43. Novel functions of proteins encoded by viral stress-inducible genes. SN Sarkar GC Sen, Pharmacol Ther 2004 103 3 245 59 10.1016/j.pharmthera.2004.07.007 15464592
44. Antiviral innate immunity pathways. RB Seth L Sun ZJ Chen, Cell Res 2006 16 2 141 7 10.1038/sj.cr.7310019 16474426
45. Soluble G protein of respiratory syncytial virus inhibits Toll-like receptor 3/4-mediated IFN-beta induction. M Shingai M Azuma T Ebihara M Sasai K Funami M Ayata H Ogura H Tsutsumi M Matsumoto T Seya, Int Immunol 2008 18611945
46. Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]. KM Spann KC Tran B Chi RL Rabin PL Collins, J Virol 2004 78 8 4363 9 15047850 10.1128/JVI.78.8.4363-4369.2004
47. Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines. KM Spann KC Tran PL Collins, J Virol 2005 79 9 5353 62 15827150 10.1128/JVI.79.9.5353-5362.2005
48. RSV 2007: Recent Advances in Respiratory Syncytial Virus Research. WW Stevens AR Falsey TJ Braciale, Viral Immunol 2008 21 2 133 40 10.1089/vim.2008.0012 18570587
49. Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha. LH Thomas JS Friedland M Sharland S Becker, J Immunol 1998 161 2 1007 16 9670982
50. The brume surrounding respiratory syncytial virus persistence. RA Tripp, Am J Respir Crit Care Med 2004 169 7 778 9 10.1164/rccm.2401013 15044217
51. Pathogenesis of respiratory syncytial virus infection. RA Tripp, Viral Immunol 2004 17 2 165 81 10.1089/0882824041310513 15279697
52. Pneumovirus and Metapneumovirus: respiratory syncytial virus and human metapneumovirus. RA Tripp Ed, Topley and Wilson's Microbiology and Microbial Infections London: Hoffer Arnold., Mahy BWJ, Meulen VT, 10 2005 2
53. Respiratory syncytial virus G and/or SH glycoproteins modify CC and CXC chemokine mRNA expression in the BALB/c mouse. RA Tripp L Jones LJ Anderson, J Virol 2000 74 13 6227 9 10846112 10.1128/JVI.74.13.6227-6229.2000
54. CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein. RA Tripp LP Jones LM Haynes H Zheng PM Murphy LJ Anderson, Nat Immunol 2001 2 8 732 8 10.1038/90675 11477410
55. Respiratory syncytial virus G and/or SH protein alters Th1 cytokines, natural killer cells, and neutrophils responding to pulmonary infection in BALB/c mice. RA Tripp D Moore L Jones W Sullender J Winter LJ Anderson, J Virol 1999 73 9 7099 107 10438795
56. Cytokines and respiratory syncytial virus infection. RA Tripp C Oshansky R Alvarez, Proc Am Thorac Soc 2005 2 2 147 9 10.1513/pats.200502-014AW 16113483
57. Characterization of murine interferon-alpha 12 (MuIFN-alpha12): biological activities and gene expression. SL Tsang PC Leung KK Leung WL Yau MP Hardy NK Mak KN Leung MC Fung, Cytokine 2007 37 2 138 49 10.1016/j.cyto.2007.03. 002 17451966
58. Respiratory syncytial virus infection of human respiratory epithelial cells enhances inducible nitric oxide synthase gene expression. H Tsutsumi R Takeuchi M Ohsaki K Seki S Chiba, J Leukoc Biol 1999 66 1 99 104 10410996
59. TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide. MK Tulic RJ Hurrelbrink CM Prele IA Laing JW Upham P Le Souef PD Sly PG Holt, J Immunol 2007 179 1 132 40 17579031
60. Infection of cultured human type II pneumonocytes with certain respiratory viruses. DA Tyrrell M Mika-Johnson G Phillips WH Douglas PJ Chapple, Infect Immun 1979 26 2 621 9 232693
61. Adhesion molecule expression on epithelial cells infected with respiratory syncytial virus. SZ Wang PG Hallsworth KD Dowling JH Alpers JJ Bowden KD Forsyth, Eur Respir J 2000 15 2 358 66 10.1034/j.1399-3003.2000.15b23. x 10706505
62. Structure and expression of human IFN-alpha genes. C Weissmann S Nagata W Boll M Fountoulakis A Fujisawa JI Fujisawa J Haynes K Henco N Mantei H Ragg C Schein J Schmid G Shaw M Streuli H Taira K Todokoro U Weidle, Philos Trans R Soc Lond B Biol Sci 1982 299 1094 7 28 10.1098/rstb.1982.0102 6128751
63. Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice. KA Wikenheiser DK Vorbroker WR Rice JC Clark CJ Bachurski HK Oie JA Whitsett, Proc Natl Acad Sci USA 1993 90 23 11029 33 8248207 10.1073/pnas.90.23.11029
64. Development of type II pneumocytes in rat lung. SL Young EK Fram CL Spain EW Larson, Am J Physiol 1991 260 2 Pt 1 L113 22 1996654
65. Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein. W Yuan RM Krug, EMBO J 2001 20 3 362 71 11157743 10.1093/emboj/20.3.362
66. Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. L Zhang ME Peeples RC Boucher PL Collins RJ Pickles, J Virol 2002 76 11 5654 66 11991994 10.1128/JVI.76.11.5654-5666.2002
67. Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene. W Zhang H Yang X Kong S Mohapatra H San Juan-Vergara G Hellermann S Behera R Singam RF Lockey SS Mohapatra, Nat Med 2005 11 1 56 62 10.1038/nm1174 15619625
68. Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways. C Zhao C Denison JM Huibregtse S Gygi RM Krug, Proc Natl Acad Sci USA 2005 102 29 10200 5 16009940 10.1073/pnas.0504754102
69. Type II pneumocyte-CD8+ T-cell interactions. Relationship between target cell cytotoxicity and activation. MQ Zhao MK Amir WR Rice RI Enelow, Am J Respir Cell Mol Biol 2001 25 3 362 9 11588015