Preparation and expression of biologically active prolactin and growth hormone receptors and suppressor of cytokine signaling proteins 1, 2, 3, and 6 tagged with cyan and yellow fluorescent proteins

Protein Expression and Purification

Volumn 25, Issue 3, 2002, Pages 456-464

  Ben Yair, Liora ^a   Slaaby, Rita ^b   Herman, Asael ^a   Cohen, Yael ^a   Biener, Eva ^a   Moran, Nava ^a   Yoshimura, Akihiko ^c   Whittaker, Jonathan ^b   De Meyts, Pierre ^b   Herman, Brian ^d   Gertler, Arieh ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HAGEDORN RESEARCH INSTITUTE   (Denmark)

^c KURUME UNIVERSITY   (Japan)

^d Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Cyan fluorescent protein; Growth hormone receptor; Prolactin receptor; SOCS proteins; Yellow fluorescent protein

Indexed keywords

ANIMALS; BACTERIAL PROTEINS; CARRIER PROTEINS; CELL LINE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; PLACENTAL LACTOGEN; PROLACTIN; PROTEIN BIOSYNTHESIS; PROTEIN TRANSPORT; PROTEINS; RECEPTORS, SOMATOTROPIN; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; SHEEP; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION;

OVIS;

EID: 0036413509     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1046-5928(02)00044-X     Document Type: Article

References (37)

1. J. Darnell, Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway, Interferon Cytokine Res. 18 (1998) 549-554.
2. H. Yasukawa, A. Sasaki, A. Yoshimura, Negative regulation of cytokine signaling pathways, Annu. Rev. Immunol. 18 (2000) 143-164.
3. R. Starr, D.J. Hilton, Negative regulation of the JAK/STAT pathway, Bioessays 21 (1999) 47-52.
4. N. Daniel, M.J. Waters, C. Bignon, J. Djiane, Involvement of a subset of tyrosine kinases and phosphatases in regulation of the beta-lactoglobulin gene promoter by prolactin, Mol. Cell Endocrinol. 118 (1996) 25-35.
5. D.L. Krebs, D.J. Hilton, SOCS proteins: Negative regulators of cytokine signaling, Stem Cells 5 (2001) 378-389.
6. T.A. Endo, M. Masuhara, M. Yokouchi, R. Suzuki, H. Sakamoto, K. Mitsui, A. Matsumoto, S. Tanimura, M. Ohtsubo, H. Misawa, T. Miyazaki, N. Leonor, T. Taniguchi, T. Fujita, Y. Kanakura, S. Komiya, A. Yoshimura, A new protein containing an SH2 domain that inhibits JAK kinases, Nature 387 (1997) 921-924.
7. T. Naka, M. Narazaki, M. Hirata, T. Matsumoto, S. Minamoto, A. Aono, N. Nishimoto, T. Kajita, T. Taga, K. Yoshizaki, S. Akira, T. Kishimoto, Structure and function of a new STAT-induced STAT inhibitor, Nature 387 (1997) 924-929.
8. H. Yasukawa, H. Misawa, H. Sakamoto, M. Masuhara, A. Sasaki, T. Wakioka, S. Ohtsuka, T. Imaizumi, T. Matsuda, J.N. Ihle, A. Yoshimura, The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop, EMBO J. 18 (1999) 1309-1320.
9. J.G. Zhang, A. Farley, S.E. Nicholson, T.A. Willson, L.M. Zugaro, R.J. Simpson, R.L. Moritz, D. Cary, R. Richardson, G. Hausmann, B.J. Kile, S.B. Kent, W.S. Alexander, D. Metcalf, D.J. Hilton, N.A. Nicola, M. Baca, The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may bound proteins to proteasomal degradation, Proc. Natl. Acad. Sci. USA 96 (1999) 2071-2076.
10. J.A. Hansen, K. Lindberg, D.J. Hilton, J.H. Nielsen, N. Billestrup, Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins, Mol. Endocrinol. 13 (1999) 1832-1843.
11. A. Pezet, H. Favre, P.A. Kelly, M. Edery, Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling, J. Biol. Chem. 274 (1999) 24497-24502.
12. S.E. Nicholson, D. De Souza, L.J. Fabri, J. Corbin, T.A. Willson, J.G. Zhang, A. Silva, M. Asimakis, A. Farley, A.D. Nash, D. Metcalf, D.J. Hilton, N.A. Nicola, M. Baca, Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130, Proc. Natl. Acad. Sci. USA 97 (2000) 6493-6498.
13. A. Gertler, J. Grosclaude, C.J. Strasburger, S. Nir, J. Djiane, Real-time kinetic measurements of the interactions between lactogenic hormones and prolactin-receptor extracellular domains from several species support the model of hormone-induced transient receptor dimerization, J. Biol. Chem. 271 (1996) 24482-24491.
14. D Helman, N.R. Staten, J. Grosclaude, N. Daniel, C. Nespoulous, J. Djiane, A. Gertler, Novel recombinant analogues of bovine placental lactogen G133K/R provide a tool to understand the diAerence between the action of prolactin and growth hormone receptors, J. Biol. Chem. 273 (1998) 16067-16074.
15. D. Helman, A. Herman, J. Paly, O. Livnah, P.A. Elkins, A.M. Devos, J. Djiane, A. Gertler, Selective mutations of ovine and bovine placental lactogens abolish biological activity mediated through homologous but not heterologous lactogenic receptors, J. Endocrinol. 168 (2001) 317-324.
16. C. Bole-Feysot, V. Goffin, M. Edery, N. Binart, P.A. Kelly, Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice, Endocr. Rev. 19 (1998) 225-268.
17. J. Herrington, L.S. Smit, J. Schwartz, C. Carter-Su, The role of STAT proteins in growth hormone signaling, Oncogene 15 (2000) 2585-2597.
18. G.W. Gordon, G. Berry, N.P. Mahajan, X.-H. Liang, B. Levine, B. Herman, Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy, Biophys. J. 74 (1998) 2702-2713.
19. N.P. Mahajan, D.C. Harrison-Shostak, J. Michaux, B. Herman, Novel mutant green fluorescent protein protease substrates reveal the activation of specific caspases during apoptosis, Chem. Biol. 6 (1999) 401-409.
20. N.P. Mahajan, K. Linder, G. Berry, G.W. Gordon, R. Tsien, R. Heim, B. Herman, Bcl-2 and bax interactions in mitochondria probed with fluorescent protein and fluorescence resonance energy transfer, Nat. Biotechnol. 16 (1998) 547-552.
21. E. Sakal, Ch. Bignon, A. Kantor, H. Leibovitch, A. Shamay, J. Djiane, A. Gertler, Large-scale preparation of recombinant ovine placental lactogen, J. Endocrinol. 152 (1997) 317-327.
22. H. Leibovich, R. Raver, A. Herman, E.L. Gregoraszczuk, E. Gootwine, A. Gertler, Large-scale preparation of recombinant ovine prolactin and determination of its in vitro and in vivo activity, Prot. Express. Purif. 22 (2001) 489-496.
23. A. Herman, D. Helman, O. Livnah, A. Gertler, Ruminant placental lactogens act as antagonists to homologous growth hormone receptors and as agonists to human or rabbit growth hormone receptors, J. Biol. Chem. 274 (1999) 7631-7639.
24. T.E. Adams, L.T. Baker, R.J. Fiddes, M.R. Brandon, The sheep growth hormone receptor: Molecular cloning and ontogeny of mRNA expression in the liver, Mol. Cell Endocrinol. 22 (1990) 135-145.
25. M. Masuhara, H. Sakamoto, A. Matsumoto, R. Suzuki, H. Yasukawa, K. Mitsui, T. Wakioka, S. Tanimura, A. Sasaki, H. Misawa, M. Yokouchi, M. Ohtsubo, A. Yoshimura, Cloning and characterization of novel CIS family genes, Biochem. Biophys. Res. Commun. 239 (1997) 439-446.
26. A. Tchelet, T. Vogel, D. Helman, R. Guy, C. Neospouolus, V. GoNn, J. Djiane, A. Gertler, Selective modification at the N-terminal region of human growth hormone (hGH) that shows antagonistic activity, Mol. Cell Endocrinol. 130 (1997) 141-152.
27. J.J. Lebrun, S. Ali, V. Goffin, A. Ulrich, P.A. Kelly, A single phosphotyrosine residue of the prolactin receptor is responsible for the activation of gene transcription, Proc. Natl. Acad. Sci. USA 92 (1995) 4031-4035.
28. J.A. VanderKuur, X. Wang, L. Zhang, G.S. Campbell, G. Allevato, N. Billestrup, G. Norstedt, C. Carter-Su, Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase, J. Biol. Chem. 269 (1994) 21709-21717.
29. P. Scott, M.A. Kessler, L.A. Schuler, Molecular cloning of the bovine prolactin receptor and distribution of prolactin and growth hormone receptor transcripts in fetal and utero-placental tissues, Mol. Cell Endocrinol. 89 (1992) 47-58.
30. C. Bignon, N. Binart, C. Ormandy, L.A. Schuler, P.A. Kelly, J. Djiane, Long and short forms of the ovine prolactin receptor: cDNA cloning and genomic analysis reveal that the two forms arise by different alternative splicing mechanisms in ruminants and in rodents, J. Mol. Endocrinol. 19 (1997) 109-120.
31. O. Goupille, N. Daniel, Ch. Bignon, G. Jolivet, J. Djiane, Prolactin signal transduction to milk protein genes: Carboxy-terminal part of the prolactin receptor and its tyrosine phosphorylation are not obligatory for JAK2 and STAT5 activation, Mol. Cell Endocrinol. 127 (1997) 155-169.
32. R.Y. Tsien, The green fluorescent protein, Annu. Rev. Biochem. 67 (1998) 509-544.
33. D. Helman, Y. Sandowski, Y. Cohen, A. Yoshimura, S. Merchav, A. Gertler, Cytokine inducible SH2 protein (CIS3) and JAK2 binding protein (JAB) abolish prolactin receptor-mediated activity, FEBS Lett. 441 (1998) 287-291.
34. C. Yeaman, K.K. Grindstaff, J.R. Wright, W.J. Nelson, Sec6/8 complexes on trans-Golgi network and plasma membrane regulate late stages of exocytosis in mammalian cells, J. Cell Biol. 155 (2001) 593-604.
35. A.A. Very, C. Bosseux, F. Gaymard, H. Sentenac, J.B. Thibaud, Level of expression in Xenopus oocytes affect some characteristics of a plant inward-rectifying voltage-gated K+ channel, Pfluegers Archiv. Eur. J. Physiol. 428 (1994) 422-424.
36. R.R. Kopito, R. Sitia, Aggresomes and Russell bodies. Symptoms of cellular indigestion? EMBO Rep. 1 (2000) 225-231.
37. R.R. Kopito, Aggresomes, inclusion bodies and protein aggregation, Trends Cell Biol. 10 (2000) 524-530.