-
1
-
-
47149089277
-
The life cycle of the metazoan nuclear envelope
-
Anderson, D. J. and Hetzer, M. W. (2008) The life cycle of the metazoan nuclear envelope. Curr. Opin. Cell Biol. 20, 386-392.
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 386-392
-
-
Anderson, D.J.1
Hetzer, M.W.2
-
2
-
-
33847176295
-
Molecular mechanism of the nuclear protein import cycle
-
Stewart, M. (2007) Molecular mechanism of the nuclear protein import cycle. Nat. Rev. Mol. Cell Biol. 8, 195-208.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 195-208
-
-
Stewart, M.1
-
3
-
-
34247135913
-
Classical nuclear localization signals: Definition, function, and interaction with importin alpha
-
Lange, A., Mills, R. E., Lange, C. J., Stewart, M., Devine, S.E., and Corbett, A. H. (2007) Classical nuclear localization signals: definition, function, and interaction with importin alpha. J. Biol. Chem. 282, 5101-5105.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 5101-5105
-
-
Lange, A.1
Mills, R.E.2
Lange, C.J.3
Stewart, M.4
Devine, S.E.5
Corbett, A.H.6
-
4
-
-
0029008267
-
Relocation of the carboxyterminal part of CAN from the nuclear envelope to the nucleus as a result of leukemia-specific chromosome rearrangements
-
Fornerod, M., Boer, J., vanBaal, S., Jaegle, M., vonLindern, M., Murti, K. G., Davis, D., Bonten, J., Buijs, A., and Grosveld, G. (1995) Relocation of the carboxyterminal part of CAN from the nuclear envelope to the nucleus as a result of leukemia-specific chromosome rearrangements. Oncogene 10, 1739-1748.
-
(1995)
Oncogene
, vol.10
, pp. 1739-1748
-
-
Fornerod, M.1
Boer, J.2
VanBaal, S.3
Jaegle, M.4
VonLindern, M.5
Murti, K.G.6
Davis, D.7
Bonten, J.8
Buijs, A.9
Grosveld, G.10
-
5
-
-
0034695924
-
The yeast nuclear pore complex. Composition, architecture, and transport mechanism
-
Rout, M. P., Aitchison, J. D., Suprapto, A., Hjertaas, K., Zhao, Y. and Chait, B. T. (2000) The yeast nuclear pore complex. Composition, architecture, and transport mechanism. J. Cell Biol. 148, 635-652.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 635-652
-
-
Rout, M.P.1
Aitchison, J.D.2
Suprapto, A.3
Hjertaas, K.4
Zhao, Y.5
Chait, B.T.6
-
6
-
-
0034126815
-
The nuclear pore complex: Mediator of translocation between nucleus and cytoplasm
-
Allen, T. D., Cronshaw, J. M., Bagley, S., Kiseleva, E., and Goldberg, M.W. (2000) The nuclear pore complex: mediator of translocation between nucleus and cytoplasm. J. Cell Sci. 113, 1651-1659. (Pubitemid 30333114)
-
(2000)
Journal of Cell Science
, vol.113
, Issue.10
, pp. 1651-1659
-
-
Allen, T.D.1
Cronshaw, J.M.2
Bagley, S.3
Kiseleva, E.4
Goldberg, M.W.5
-
7
-
-
0037604556
-
Peering through the pore. Nuclear pore complex structure, assembly, and function
-
Suntharalingam, M. and Wente, S. R. (2003) Peering through the pore. Nuclear pore complex structure, assembly, and function. Dev. Cell 4, 775-789.
-
(2003)
Dev. Cell
, vol.4
, pp. 775-789
-
-
Suntharalingam, M.1
Wente, S.R.2
-
8
-
-
36749045172
-
The molecular architecture of the nuclear pore complex
-
Alber, F., Dokudovskaya, S., Veenhoff, L. M., Zhang, W., Kipper, J., Devos, D., Suprapto, A., Karni-Schmidt, O., Williams, R., Chait, B. T., Sali, A., and Rout, M. P. (2007) The molecular architecture of the nuclear pore complex. Nature 450, 695-701.
-
(2007)
Nature
, vol.450
, pp. 695-701
-
-
Alber, F.1
Dokudovskaya, S.2
Veenhoff, L.M.3
Zhang, W.4
Kipper, J.5
Devos, D.6
Suprapto, A.7
Karni-Schmidt, O.8
Williams, R.9
Chait, B.T.10
Sali, A.11
Rout, M.P.12
-
9
-
-
32944470084
-
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells
-
Burczynski, M. E., Peterson, R. L., Twine, N. C., Zuberek, K. A., Brodeur, B. J., Casciotti, L., Maganti, V., Reddy, P. S., Strahs, A., Immermann, F., Spinelli, W., Schwertschlag, U., Slager, A. M., Cotreau, M. M., and Dorner, A. J. (2006) Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. J. Mol. Diagn. 8, 51-61.
-
(2006)
J. Mol. Diagn.
, vol.8
, pp. 51-61
-
-
Burczynski, M.E.1
Peterson, R.L.2
Twine, N.C.3
Zuberek, K.A.4
Brodeur, B.J.5
Casciotti, L.6
Maganti, V.7
Reddy, P.S.8
Strahs, A.9
Immermann, F.10
Spinelli, W.11
Schwertschlag, U.12
Slager, A.M.13
Cotreau, M.M.14
Dorner, A.J.15
-
10
-
-
1542609480
-
Minimal nuclear pore complexes define FG repeat domains essential for transport
-
Strawn, L. A., Shen, T., Shulga, N., Goldfarb, D. S., and Wente, S. R. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat. Cell Biol. 6, 197-206.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 197-206
-
-
Strawn, L.A.1
Shen, T.2
Shulga, N.3
Goldfarb, D.S.4
Wente, S.R.5
-
11
-
-
0016652057
-
Nuclear envelope permeability
-
Paine, P. L., Moore, L. C., and Horowitz, S. B. (1975) Nuclear envelope permeability. Nature 254, 109-114.
-
(1975)
Nature
, vol.254
, pp. 109-114
-
-
Paine, P.L.1
Moore, L.C.2
Horowitz, S.B.3
-
13
-
-
38349187678
-
Nucleocytoplasmic transport of proteins
-
Sorokin, A. V., Kim, E. R., and Ovchinnikov, L. P. (2007) Nucleocytoplasmic transport of proteins. Biochemistry (Mosc) 72, 1439-1457.
-
(2007)
Biochemistry (Mosc)
, vol.72
, pp. 1439-1457
-
-
Sorokin, A.V.1
Kim, E.R.2
Ovchinnikov, L.P.3
-
14
-
-
4644278442
-
Karyopherins: From nuclear-transport mediators to nuclear-function regulators
-
DOI 10.1016/j.tcb.2004.09.004, PII S0962892404002363
-
Mosammaparast, N. and Pemberton, L. F. (2004) Karyopherins: from nuclear-transport mediators to nuclear-function regulators. Trends Cell Biol. 14, 547-556. (Pubitemid 39296617)
-
(2004)
Trends in Cell Biology
, vol.14
, Issue.10
, pp. 547-556
-
-
Mosammaparast, N.1
Pemberton, L.F.2
-
15
-
-
0035846901
-
Importin beta is a mitotic target of the small GTPase ran in spindle assembly
-
DOI 10.1016/S0092-8674(01)00194-5
-
Nachury, M. V., Maresca, T. J., Salmon, W. C., Waterman-Storer, C. M., Heald, R., and Weis, K. (2001) Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. Cell 104, 95-106. (Pubitemid 32144975)
-
(2001)
Cell
, vol.104
, Issue.1
, pp. 95-106
-
-
Nachury, M.V.1
Maresca, T.J.2
Salmon, W.C.3
Waterman-Storer, C.M.4
Heald, R.5
Weis, K.6
-
16
-
-
18844474983
-
Karyopherins and kissing cousins
-
Wozniak, R. W., Rout, M. P., and Aitchison, J. D. (1998) Karyopherins and kissing cousins. Trends Cell Biol. 8, 184-188.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 184-188
-
-
Wozniak, R.W.1
Rout, M.P.2
Aitchison, J.D.3
-
18
-
-
0034913423
-
Importin-beta-like nuclear transport receptors
-
Reviews 3008
-
Strom, A. C. and Weis, K. (2001) Importin-beta-like nuclear transport receptors. Genome Biol. 2, Reviews 3008.
-
(2001)
Genome Biol.
, vol.2
-
-
Strom, A.C.1
Weis, K.2
-
19
-
-
0033279841
-
Transport between the cell nucleus and the cytoplasm
-
Görlich, D. and Kutay, U. (1999) Transport between the cell nucleus and the cytoplasm. Annu. Rev. Cell Dev. Biol. 15, 607-660.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 607-660
-
-
Görlich, D.1
Kutay, U.2
-
20
-
-
0029392854
-
HEAT repeats in the Huntington's disease protein
-
Andrade, M. A. and Bork, P. (1995) HEAT repeats in the Huntington's disease protein. Nat. Genet. 11, 115-116.
-
(1995)
Nat. Genet.
, vol.11
, pp. 115-116
-
-
Andrade, M.A.1
Bork, P.2
-
21
-
-
0038699131
-
The small GTPase Ran: Interpreting the signs
-
Quimby, B. B. and Dasso, M. (2003) The small GTPase Ran: interpreting the signs. Curr. Opin. Cell Biol., 15, 338-344.
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 338-344
-
-
Quimby, B.B.1
Dasso, M.2
-
22
-
-
0033151769
-
The nuclear pore complex: From molecular architecture to functional dynamics
-
Stoffler, D., Fahrenkrog, B., and Aebi, U. (1999) The nuclear pore complex: from molecular architecture to functional dynamics. Curr. Opin. Cell Biol. 11, 391-401.
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 391-401
-
-
Stoffler, D.1
Fahrenkrog, B.2
Aebi, U.3
-
23
-
-
0036264236
-
Regulation of nuclear import and export by the GTPase Ran
-
Steggerda, S. M. and Paschal, B. M. (2002) Regulation of nuclear import and export by the GTPase Ran. Int. Rev. Cytol. 217, 41-91.
-
(2002)
Int. Rev. Cytol.
, vol.217
, pp. 41-91
-
-
Steggerda, S.M.1
Paschal, B.M.2
-
24
-
-
53149119873
-
Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: Implications for nuclear import complex assembly dynamics
-
Forwood, J. K., Lonhienne, T. G., Marfori, M., Robin, G., Meng, W., Guncar, G., Liu, S. M., Stewart, M., Carroll, B. J., and Kobe, B. (2008) Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J. Mol. Biol. 383, 772-782.
-
(2008)
J. Mol. Biol.
, vol.383
, pp. 772-782
-
-
Forwood, J.K.1
Lonhienne, T.G.2
Marfori, M.3
Robin, G.4
Meng, W.5
Guncar, G.6
Liu, S.M.7
Stewart, M.8
Carroll, B.J.9
Kobe, B.10
-
25
-
-
20444468112
-
Structural basis for nuclear import complex dissociation by RanGTP
-
DOI 10.1038/nature03578
-
Lee, S. J., Matsuura, Y., Liu, S. M., and Stewart, M. (2005) Structural basis for nuclear import complex dissociation by RanGTP. Nature 435, 693-696. (Pubitemid 40825515)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 693-696
-
-
Lee, S.J.1
Matsuura, Y.2
Liu, S.M.3
Stewart, M.4
-
26
-
-
4444291705
-
Importin alpha: A multipurpose nuclear-transport receptor
-
Goldfarb, D. S., Corbett, A. H., Mason, D. A., Harreman, M. T., and Adam, S. A. (2004) Importin alpha: a multipurpose nuclear-transport receptor. Trends Cell Biol. 14, 505-514.
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 505-514
-
-
Goldfarb, D.S.1
Corbett, A.H.2
Mason, D.A.3
Harreman, M.T.4
Adam, S.A.5
-
27
-
-
0032189258
-
Signal sequences: More than just greasy peptides
-
DOI 10.1016/S0962-8924(98)01360-9
-
Martoglio, B. and Dobberstein, B. (1998) Signal sequences: more than just greasy peptides. Trends Cell Biol. 8, 410-415. (Pubitemid 28458707)
-
(1998)
Trends in Cell Biology
, vol.8
, Issue.10
, pp. 410-415
-
-
Martoglio, B.1
Dobberstein, B.2
-
28
-
-
0025949412
-
Nuclear targeting sequences - A consensus?
-
Dingwall, C. and Laskey, R. A. (1991) Nuclear targeting sequences - a consensus? Trends Biochem. Sci. 16, 478-481.
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 478-481
-
-
Dingwall, C.1
Laskey, R.A.2
-
29
-
-
0021269089
-
Sequence requirements for nuclear location of simian virus 40 large-T antigen
-
Kalderon, D., Richardson, W. D., Markham, A. F., and Smith, A. E. (1984) Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature 311, 33-38. (Pubitemid 14065276)
-
(1984)
Nature
, vol.311
, Issue.5981
, pp. 33-38
-
-
Kalderon, D.1
Richardson, W.D.2
Markham, A.F.3
Smith, A.E.4
-
30
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
Kalderon, D., Roberts, B. L., Richardson, W. D., and Smith, A. E. (1984) A short amino acid sequence able to specify nuclear location. Cell 39, 499-509. (Pubitemid 15198589)
-
(1984)
Cell
, vol.39
, Issue.3
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
31
-
-
0026078249
-
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
-
Robbins, J., Dilworth, S. M., Laskey, R. A., and Dingwall, C. (1991) Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 64, 615-623. (Pubitemid 121002977)
-
(1991)
Cell
, vol.64
, Issue.3
, pp. 615-623
-
-
Robbins, J.1
Dilworth, S.M.2
Laskey, R.A.3
Dingwall, C.4
-
32
-
-
0142164604
-
Two independent nuclear localization signals are present in the DNA-binding high-mobility group domains of SRY and SOX9
-
Sudbeck, P. and Scherer, G. (1997) Two independent nuclear localization signals are present in the DNA-binding high-mobility group domains of SRY and SOX9. J. Biol. Chem. 272, 27848-27852.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27848-27852
-
-
Sudbeck, P.1
Scherer, G.2
-
33
-
-
0035824629
-
The C-terminal nuclear localization signal of the sex-determining region Y (SRY) high mobility group domain mediates nuclear import through importin beta 1
-
Forwood, J. K., Harley, V., and Jans, D. A. (2001) The C-terminal nuclear localization signal of the sex-determining region Y (SRY) high mobility group domain mediates nuclear import through importin beta 1. J. Biol. Chem. 276, 46575-46582.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46575-46582
-
-
Forwood, J.K.1
Harley, V.2
Jans, D.A.3
-
34
-
-
0028943643
-
Nuclear localization of the testis determining gene product SRY
-
Poulat, F., Girard, F., Chevron, M. P., Goze, C., Rebillard, X., Calas, B., Lamb, N., and Berta, P. (1995) Nuclear localization of the testis determining gene product SRY. J. Cell Biol. 128, 737-748.
-
(1995)
J. Cell Biol.
, vol.128
, pp. 737-748
-
-
Poulat, F.1
Girard, F.2
Chevron, M.P.3
Goze, C.4
Rebillard, X.5
Calas, B.6
Lamb, N.7
Berta, P.8
-
35
-
-
33746776838
-
Rules for Nuclear Localization Sequence Recognition by Karyopherinbeta2
-
DOI 10.1016/j.cell.2006.05.049, PII S009286740600910X
-
Lee, B. J., Cansizoglu, A. E., Suel, K. E., Louis, T. H., Zhang, Z., and Chook, Y. M. (2006) Rules for nuclear localization sequence recognition by karyopherin beta 2. Cell 126, 543-558. (Pubitemid 44163605)
-
(2006)
Cell
, vol.126
, Issue.3
, pp. 543-558
-
-
Lee, B.J.1
Cansizoglu, A.E.2
Suel, K.E.3
Louis, T.H.4
Zhang, Z.5
Chook, Y.M.6
-
36
-
-
45149113882
-
A PY-NLS nuclear targeting signal is required for nuclear localization and function of the Saccharomyces cerevisiae mRNA-binding protein Hrp1
-
Lange, A., Mills, R. E., Devine, S. E., and Corbett, A. H. (2008) A PY-NLS nuclear targeting signal is required for nuclear localization and function of the Saccharomyces cerevisiae mRNA-binding protein Hrp1. J. Biol. Chem. 283, 12926-12934.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 12926-12934
-
-
Lange, A.1
Mills, R.E.2
Devine, S.E.3
Corbett, A.H.4
-
37
-
-
0037023770
-
Characterization of an unusual importin alpha binding motif in the borna disease virus p10 protein that directs nuclear import
-
Wolff, T., Unterstab, G., Heins, G., Richt, J. A., and Kann, M. (2002) Characterization of an unusual importin alpha binding motif in the borna disease virus p10 protein that directs nuclear import. J. Biol. Chem. 277, 12151-12157.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12151-12157
-
-
Wolff, T.1
Unterstab, G.2
Heins, G.3
Richt, J.A.4
Kann, M.5
-
38
-
-
15444368332
-
Phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin alpha
-
Chen, M. H., Ben-Efraim, I., Mitrousis, G., Walker-Kopp, N., Sims, P. J., and Cingolani, G. (2005) Phospholipid scramblase 1 contains a nonclassical nuclear localization signal with unique binding site in importin alpha. J. Biol. Chem. 280, 10599-10606.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 10599-10606
-
-
Chen, M.H.1
Ben-Efraim, I.2
Mitrousis, G.3
Walker-Kopp, N.4
Sims, P.J.5
Cingolani, G.6
-
39
-
-
0031883281
-
A Ty1 integrase nuclear localization signal required for retrotransposition
-
Moore, S. P., Rinckel, L. A., and Garfinkel, D. J. (1998) A Ty1 integrase nuclear localization signal required for retrotransposition. Mol. Cell Biol. 18, 1105-1114.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 1105-1114
-
-
Moore, S.P.1
Rinckel, L.A.2
Garfinkel, D.J.3
-
40
-
-
0031883282
-
Invading the yeast nucleus: A nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo
-
Kenna, M. A., Brachmann, C. B., Devine, S. E., and Boeke, J. D. (1998) Invading the yeast nucleus: a nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo. Mol. Cell Biol. 18, 1115-1124.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 1115-1124
-
-
Kenna, M.A.1
Brachmann, C.B.2
Devine, S.E.3
Boeke, J.D.4
-
41
-
-
48349125312
-
The Ty1 integrase protein can exploit the classical nuclear protein import machinery for entry into the nucleus
-
McLane, L. M., Pulliam, K. F., Devine, S. E., and Corbett, A. H. (2008) The Ty1 integrase protein can exploit the classical nuclear protein import machinery for entry into the nucleus. Nucleic Acids Res. 36, 4317-4326.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 4317-4326
-
-
McLane, L.M.1
Pulliam, K.F.2
Devine, S.E.3
Corbett, A.H.4
-
42
-
-
0025141758
-
Identification of sequences important in the nucleolar localization human immunodeficiency virus Rev: Relevance of nucleolar localization to function
-
Cochrane, A. W., Perkins, A., and Rosen, C. A. (1990) Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function. J. Virol. 64, 881-885. (Pubitemid 20032706)
-
(1990)
Journal of Virology
, vol.64
, Issue.2
, pp. 881-885
-
-
Cochrane, A.W.1
Perkins, A.2
Rosen, C.A.3
-
43
-
-
0024756963
-
A region of basic amino-acid cluster in HIV-1 Tat protein is essential for trans-acting activity and nucleolar localization
-
Endo, S., Kubota, S., Siomi, H., Adachi, A., Oroszlan, S., Maki, M., and Hatanaka, M. (1989) A region of basic amino-acid cluster in HIV-1 Tat protein is essential for trans-acting activity and nucleolar localization. Virus Genes 3, 99-110.
-
(1989)
Virus Genes
, vol.3
, pp. 99-110
-
-
Endo, S.1
Kubota, S.2
Siomi, H.3
Adachi, A.4
Oroszlan, S.5
Maki, M.6
Hatanaka, M.7
-
44
-
-
0032911885
-
The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals
-
Truant, R., and Cullen, B. R. (1999) The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals. Mol. Cell Biol. 19, 1210-1217.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 1210-1217
-
-
Truant, R.1
Cullen, B.R.2
-
45
-
-
0036210710
-
Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast
-
Leslie, D. M., Grill, B., Rout, M. P., Wozniak, R. W., and Aitchison, J. D. (2002) Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast. Mol. Cell Biol. 22, 2544-2555.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 2544-2555
-
-
Leslie, D.M.1
Grill, B.2
Rout, M.P.3
Wozniak, R.W.4
Aitchison, J.D.5
-
46
-
-
0032530850
-
Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK
-
Bardwell, L., Cook, J. G., Voora, D., Baggott, D. M., Martinez, A. R., and Thorner, J. (1998) Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. Genes Dev. 12, 2887-2898. (Pubitemid 28440147)
-
(1998)
Genes and Development
, vol.12
, Issue.18
, pp. 2887-2898
-
-
Bardwell, L.1
Cook, J.G.2
Voora, D.3
Baggott, D.M.4
Martinez, A.R.5
Thorner, J.6
-
47
-
-
0028670651
-
Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: Mating and invasive growth
-
Roberts, R. L. and Fink, G. R. (1994) Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth. Genes Dev. 8, 2974-2985.
-
(1994)
Genes Dev.
, vol.8
, pp. 2974-2985
-
-
Roberts, R.L.1
Fink, G.R.2
-
48
-
-
0032168565
-
Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121
-
Kaffman, A., Rank, N. M., and O'Shea, E. K. (1998) Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. Genes Dev. 12, 2673-2683. (Pubitemid 28420648)
-
(1998)
Genes and Development
, vol.12
, Issue.17
, pp. 2673-2683
-
-
Kaffman, A.1
Rank, N.M.2
O'Shea, E.K.3
-
49
-
-
0035877849
-
Nuclear import of the yeast AP-1-like transcription factor Yap1p is mediated by transport receptor Pse1p, and this import step is not affected by oxidative stress
-
Isoyama, T., Murayama, A., Nomoto, A., and Kuge, S. (2001) Nuclear import of the yeast AP-1-like transcription factor Yap1p is mediated by transport receptor Pse1p, and this import step is not affected by oxidative stress. J. Biol. Chem. 276, 21863-21869.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21863-21869
-
-
Isoyama, T.1
Murayama, A.2
Nomoto, A.3
Kuge, S.4
-
50
-
-
0024638464
-
Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins
-
Moye-Rowley, W. S., Harshman, K. D., and Parker, C. S. (1989) Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins. Genes Dev. 3, 283-292.
-
(1989)
Genes Dev
, vol.3
, pp. 283-292
-
-
Moye-Rowley, W.S.1
Harshman, K.D.2
Parker, C.S.3
-
51
-
-
0020188311
-
A polypeptide domain that specifies migration of nucleoplasmin into the nucleus
-
Dingwall, C., Sharnick, S. V., and Laskey, R. A. A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell, 30, 449-458.
-
Cell
, vol.30
, pp. 449-458
-
-
Dingwall, C.1
Sharnick, S.V.2
Laskey, R.A.3
-
52
-
-
0034646565
-
Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha
-
Fontes, M. R., Teh, T., and Kobe, B. (2000) Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha. J. Mol. Biol. 297, 1183-1194.
-
(2000)
J. Mol. Biol.
, vol.297
, pp. 1183-1194
-
-
Fontes, M.R.1
Teh, T.2
Kobe, B.3
-
53
-
-
0041845285
-
Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
-
Fontes, M. R., Teh, T., Jans, D., Brinkworth, R. I., and Kobe, B. (2003) Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha. J. Biol. Chem. 278, 27981-27987.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27981-27987
-
-
Fontes, M.R.1
Teh, T.2
Jans, D.3
Brinkworth, R.I.4
Kobe, B.5
-
54
-
-
0032950628
-
Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin a
-
Kobe, B. (1999) Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin a. Nat. Struct. Biol. 6, 301-304.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 301-304
-
-
Kobe, B.1
-
55
-
-
0032563246
-
Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha
-
DOI 10.1016/S0092-8674(00)81419-1
-
Conti, E., Uy, M., Leighton, L., Blobel, G., and Kuriyan, J. (1998) Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell 94, 193-204. (Pubitemid 28348007)
-
(1998)
Cell
, vol.94
, Issue.2
, pp. 193-204
-
-
Conti, E.1
Uy, M.2
Leighton, L.3
Blobel, G.4
Kuriyan, J.5
-
56
-
-
0034653375
-
Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha
-
Conti, E. and Kuriyan, J. (2000) Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Struct. Fold Des. 8, 329-338.
-
(2000)
Struct. Fold Des.
, vol.8
, pp. 329-338
-
-
Conti, E.1
Kuriyan, J.2
-
57
-
-
0142231575
-
Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
-
DOI 10.1042/BJ20030510
-
Fontes, M. R., Teh, T., Toth, G., John, A., Pavo, I., Jans, D. A., and Kobe, B. (2003) Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha. Biochem. J. 375, 339-349. (Pubitemid 37315442)
-
(2003)
Biochemical Journal
, vol.375
, Issue.2
, pp. 339-349
-
-
Fontes, M.R.M.1
Teh, T.2
Toth, G.3
John, A.4
Pavo, I.5
Jans, D.A.6
Kobe, B.7
-
58
-
-
33847624936
-
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit
-
Tarendeau, F., Boudet, J., Guilligay, D., Mas, P. J., Bougault, C. M., Boulo, S., Baudin, F., Ruigrok, R. W., Daigle, N., Ellenberg, J., et al. (2007) Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat. Struct. Mol. Biol. 14, 229-233.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 229-233
-
-
Tarendeau, F.1
Boudet, J.2
Guilligay, D.3
Mas, P.J.4
Bougault, C.M.5
Boulo, S.6
Baudin, F.7
Ruigrok, R.W.8
Daigle, N.9
Ellenberg, J.10
-
59
-
-
43149125406
-
Structural basis for the nuclear import of the human androgen receptor
-
DOI 10.1242/jcs.022103
-
Cutress, M. L., Whitaker, H. C., Mills, I. G., Stewart, M., and Neal, D. E. (2008) Structural basis for the nuclear import of the human androgen receptor. J. Cell Sci. 121, 957-968. (Pubitemid 351639415)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.7
, pp. 957-968
-
-
Cutress, M.L.1
Whitaker, H.C.2
Mills, I.G.3
Stewart, M.4
Neal, D.E.5
-
60
-
-
0142149147
-
Dissection of the karyopherin alpha nuclear localization signal (NLS)-binding groove: Functional requirements for NLS binding
-
Leung, S. W., Harreman, M. T., Hodel, M. R., Hodel, A. E., and Corbett, A. H. (2003) Dissection of the karyopherin alpha nuclear localization signal (NLS)-binding groove: functional requirements for NLS binding. J. Biol. Chem. 278, 41947-41953.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 41947-41953
-
-
Leung, S.W.1
Harreman, M.T.2
Hodel, M.R.3
Hodel, A.E.4
Corbett, A.H.5
-
61
-
-
0035933149
-
Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I
-
Gross, S. and Moore, C. (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc. Natl. Acad. Sci. USA 98, 6080-6085.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6080-6085
-
-
Gross, S.1
Moore, C.2
-
62
-
-
45849096845
-
Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signals
-
Suel, K. E., Gu, H., and Chook, Y. M. (2008) Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signals. PLoS Biol. 6, e137.
-
(2008)
PLoS Biol
, vol.6
-
-
Suel, K.E.1
Gu, H.2
Chook, Y.M.3
-
63
-
-
0037333846
-
A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway
-
Lischka, P., Sorg, G., Kann, M., Winkler, M., and Stamminger, T. (2003) A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway. J. Virol. 77, 3734-3748.
-
(2003)
J. Virol.
, vol.77
, pp. 3734-3748
-
-
Lischka, P.1
Sorg, G.2
Kann, M.3
Winkler, M.4
Stamminger, T.5
-
64
-
-
0035844291
-
Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs
-
Melen, K., Kinnunen, L., and Julkunen, I. (2001) Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs. J. Biol. Chem. 276, 16447-16455.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16447-16455
-
-
Melen, K.1
Kinnunen, L.2
Julkunen, I.3
-
65
-
-
0034913423
-
Importin-beta-like nuclear transport receptors
-
Reviews 3008
-
Strom, A. C. and Weis, K. (2001) Importin-beta-like nuclear transport receptors. Genome Biol. 2, Reviews 3008.
-
(2001)
Genome Biol.
, vol.2
-
-
Strom, A.C.1
Weis, K.2
-
66
-
-
0032961356
-
Importin beta can mediate the nuclear import of an arginine-rich nuclear localization signal in the absence of importin alpha
-
Palmeri, D. and Malim, M. H. (1999) Importin beta can mediate the nuclear import of an arginine-rich nuclear localization signal in the absence of importin alpha. Mol. Cell Biol. 19, 1218-1225.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 1218-1225
-
-
Palmeri, D.1
Malim, M.H.2
-
67
-
-
0032168565
-
Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121
-
Kaffman, A., Rank, N. M., and O'Shea, E. K. (1998) Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. Genes Dev. 12, 2673-2683. (Pubitemid 28420648)
-
(1998)
Genes and Development
, vol.12
, Issue.17
, pp. 2673-2683
-
-
Kaffman, A.1
Rank, N.M.2
O'Shea, E.K.3
-
68
-
-
33751222250
-
Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo
-
DOI 10.1083/jcb.200608141
-
Timney, B. L., Tetenbaum-Novatt, J., Agate, D. S., Williams, R., Zhang, W., Chait, B. T., and Rout, M. P. (2006) Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo. J Cell Biol. 175, 579-593. (Pubitemid 44790612)
-
(2006)
Journal of Cell Biology
, vol.175
, Issue.4
, pp. 579-593
-
-
Timney, B.L.1
Tetenbaum-Novatt, J.2
Agate, D.S.3
Williams, R.4
Zhang, W.5
Chait, B.T.6
Rout, M.P.7
-
69
-
-
33747697156
-
Nuclear localization signal receptor affinity correlates with in vivo localization in Saccharomyces cerevisiae
-
Hodel, A. E., Harreman, M. T., Pulliam, K. F., Harben, M. E., Holmes, J. S., Hodel, M. R., Berland, K.M., and Corbett, A. H. (2006) Nuclear localization signal receptor affinity correlates with in vivo localization in Saccharomyces cerevisiae. J. Biol. Chem. 281, 23545-23556.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23545-23556
-
-
Hodel, A.E.1
Harreman, M.T.2
Pulliam, K.F.3
Harben, M.E.4
Holmes, J.S.5
Hodel, M.R.6
Berland, K.M.7
Corbett, A.H.8
-
70
-
-
0033578021
-
Nuclear transport: Randy couples
-
Macara, I. G. (1999) Nuclear transport: randy couples. Curr Biol. 9, R436-R439.
-
(1999)
Curr Biol.
, vol.9
-
-
Macara, I.G.1
-
71
-
-
7244255836
-
Getting the message across, STAT! Design principles of a molecular signaling circuit
-
Vinkemeier, U. (2004) Getting the message across, STAT! Design principles of a molecular signaling circuit. J. Cell Biol. 167, 197-201.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 197-201
-
-
Vinkemeier, U.1
-
72
-
-
0034041537
-
Nuclear targeting signal recognition: A key control point in nuclear transport?
-
Jans, D. A., Xiao, C. Y., and Lam, M. H. (2000) Nuclear targeting signal recognition: a key control point in nuclear transport? Bioessays 22, 532-544.
-
(2000)
Bioessays
, vol.22
, pp. 532-544
-
-
Jans, D.A.1
Xiao, C.Y.2
Lam, M.H.3
-
73
-
-
1042278767
-
Nuclear transport and cancer: From mechanism to intervention
-
Kau, T. R., Way, J. C., and Silver, P. A. (2004) Nuclear transport and cancer: from mechanism to intervention. Nat. Rev. Cancer 4, 106-117.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 106-117
-
-
Kau, T.R.1
Way, J.C.2
Silver, P.A.3
-
74
-
-
33746038130
-
Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer
-
Dahl, E., Kristiansen, G., Gottlob, K., Klaman, I., Ebner, E., Hinzmann, B., Hermann, K., Pilarsky, C., Durst, M., Klinkhammer-Schalke, M., et al. (2006) Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer. Clin. Cancer Res. 12, 3950-3960.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 3950-3960
-
-
Dahl, E.1
Kristiansen, G.2
Gottlob, K.3
Klaman, I.4
Ebner, E.5
Hinzmann, B.6
Hermann, K.7
Pilarsky, C.8
Durst, M.9
Klinkhammer-Schalke, M.10
-
75
-
-
33645739022
-
Gene expression profiling of primary cutaneous melanoma and clinical outcome
-
Winnepenninckx, V., Lazar, V., Michiels, S., Dessen, P., Stas, M., Alonso, S. R., Avril, M. F., Ortiz Romero, P. L., Robert, T., Balacescu, O., et al. (2006) Gene expression profiling of primary cutaneous melanoma and clinical outcome. J. Natl. Cancer Inst. 98, 472-482.
-
(2006)
J. Natl. Cancer Inst.
, vol.98
, pp. 472-482
-
-
Winnepenninckx, V.1
Lazar, V.2
Michiels, S.3
Dessen, P.4
Stas, M.5
Alonso, S.R.6
Avril, M.F.7
Ortiz Romero, P.L.8
Robert, T.9
Balacescu, O.10
-
76
-
-
0034725636
-
Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53
-
Kim, I. S., Kim, D. H., Han, S. M., Chin, M. U., Nam, H. J., Cho, H. P., Choi, S. Y., Song, B. J., Kim, E. R., Bae, Y. S., et al. (2000) Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53. J. Biol. Chem. 275, 23139-23145.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23139-23145
-
-
Kim, I.S.1
Kim, D.H.2
Han, S.M.3
Chin, M.U.4
Nam, H.J.5
Cho, H.P.6
Choi, S.Y.7
Song, B.J.8
Kim, E.R.9
Bae, Y.S.10
-
77
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko, L. J. and Prives, C. (1996) p53: puzzle and paradigm. Genes Dev. 10, 1054-1072.
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
78
-
-
0026694826
-
Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
-
Moll, U. M., Riou, G., and Levine, A. J. (1992) Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc. Natl. Acad. Sci. USA 89, 7262-7266.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7262-7266
-
-
Moll, U.M.1
Riou, G.2
Levine, A.J.3
-
79
-
-
0029049828
-
Wildtype p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
-
Moll, U. M., LaQuaglia, M., Benard, J., and Riou, G. (1995) Wildtype p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc. Natl. Acad. Sci. US A 92, 4407-4411.
-
(1995)
Proc. Natl. Acad. Sci. US A
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
Laquaglia, M.2
Benard, J.3
Riou, G.4
-
80
-
-
0028978774
-
p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma
-
Bosari, S., Viale, G., Roncalli, M., Graziani, D., Borsani, G., Lee, A. K., and Coggi, G. (1995) p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma. Am. J. Pathol. 147, 790-798.
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 790-798
-
-
Bosari, S.1
Viale, G.2
Roncalli, M.3
Graziani, D.4
Borsani, G.5
Lee, A.K.6
Coggi, G.7
-
81
-
-
0038810142
-
Defective importin beta recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations
-
Harley, V. R., Layfield, S., Mitchell, C. L., Forwood, J. K., John, A. P., Briggs, L. J., McDowall, S. G., and Jans, D. A. (2003) Defective importin beta recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations. Proc. Natl. Acad. Sci. USA 100, 7045-7050.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7045-7050
-
-
Harley, V.R.1
Layfield, S.2
Mitchell, C.L.3
Forwood, J.K.4
John, A.P.5
Briggs, L.J.6
McDowall, S.G.7
Jans, D.A.8
-
82
-
-
0035824513
-
Human sex reversal due to impaired nuclear localization of SRY. A clinical correlation
-
Li, B., Zhang, W., Chan, G., Jancso-Radek, A., Liu, S., and Weiss, M. A. (2001) Human sex reversal due to impaired nuclear localization of SRY. A clinical correlation. J. Biol. Chem. 276, 46480-46484.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46480-46484
-
-
Li, B.1
Zhang, W.2
Chan, G.3
Jancso-Radek, A.4
Liu, S.5
Weiss, M.A.6
-
83
-
-
0025250731
-
Genetic evidence equating SRY and the testis-determining factor
-
Berta, P., Hawkins, J. R., Sinclair, A. H., Taylor, A., Griffiths, B. L., Goodfellow, P. N., and Fellous, M. (1990) Genetic evidence equating SRY and the testis-determining factor. Nature 348, 448-450. (Pubitemid 120015086)
-
(1990)
Nature
, vol.348
, Issue.6300
, pp. 448-450
-
-
Berta, P.1
Hawkins, J.R.2
Sinclair, A.H.3
Taylor, A.4
Griffiths, B.L.5
Goodfellow, P.N.6
Fellous, M.7
-
84
-
-
0025328296
-
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes
-
DOI 10.1038/346245a0
-
Gubbay, J., Collignon, J., Koopman, P., Capel, B., Economou, A., Munsterberg, A., Vivian, N., Goodfellow, P., and Lovell-Badge, R. (1990) A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 346, 245-250. (Pubitemid 20227397)
-
(1990)
Nature
, vol.346
, Issue.6281
, pp. 245-250
-
-
Gubbay, J.1
Collignon, J.2
Koopman, P.3
Capel, B.4
Economou, A.5
Munsterberg, A.6
Vivian, N.7
Goodfellow, P.8
Lovell-Badge, R.9
-
85
-
-
0027936497
-
Sex determination
-
Hawkins, J. R. (1994) Sex determination. Hum. Mol. Genet. 3, 1463-1467.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1463-1467
-
-
Hawkins, J.R.1
-
86
-
-
0027050688
-
A familial mutation in the testis-determining gene SRY shared by both sexes
-
Jager, R. J., Harley, V. R., Pfeiffer, R. A., Goodfellow, P. N., and Scherer, G. (1992) A familial mutation in the testis-determining gene SRY shared by both sexes. Hum. Genet. 90, 350-355.
-
(1992)
Hum. Genet.
, vol.90
, pp. 350-355
-
-
Jager, R.J.1
Harley, V.R.2
Pfeiffer, R.A.3
Goodfellow, P.N.4
Scherer, G.5
-
87
-
-
0036432466
-
Biochemical defects in eight SRY missense mutations causing XY gonadal dysgenesis
-
Mitchell, C. L., and Harley, V. R. (2002) Biochemical defects in eight SRY missense mutations causing XY gonadal dysgenesis. Mol. Genet. Metab. 77, 217-225.
-
(2002)
Mol. Genet. Metab.
, vol.77
, pp. 217-225
-
-
Mitchell, C.L.1
Harley, V.R.2
-
88
-
-
0027253046
-
Analysis of the SRY gene in 22 sex-reversed XY females identifies four new point mutations in the conserved DNA binding domain
-
Affara, N. A., Chalmers, I. J., and Ferguson-Smith, M. A. (1993) Analysis of the SRY gene in 22 sex-reversed XY females identifies four new point mutations in the conserved DNA binding domain. Hum. Mol. Genet. 2, 785-789.
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 785-789
-
-
Affara, N.A.1
Chalmers, I.J.2
Ferguson-Smith, M.A.3
-
89
-
-
0031411417
-
A novel double nucleotide substitution in the HMG box of the SRY gene associated with Swyer syndrome
-
Battiloro, E., Angeletti, B., Tozzi, M. C., Bruni, L., Tondini, S., Vignetti, P., Verna, R., and D'Ambrosio, E. (1997) A novel double nucleotide substitution in the HMG box of the SRY gene associated with Swyer syndrome. Hum. Genet. 100, 585-587.
-
(1997)
Hum. Genet.
, vol.100
, pp. 585-587
-
-
Battiloro, E.1
Angeletti, B.2
Tozzi, M.C.3
Bruni, L.4
Tondini, S.5
Vignetti, P.6
Verna, R.7
D'Ambrosio, E.8
-
90
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet, B. and Gelinas, C. (1999) Aberrant rel/nfkb genes and activity in human cancer. Oncogene 18, 6938-6947.
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
91
-
-
0034283837
-
The Rel/NF-kappa B family: Friend and foe
-
Perkins, N. D. (2000) The Rel/NF-kappa B family: friend and foe. Trends Biochem. Sci. 25, 434-440.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 434-440
-
-
Perkins, N.D.1
-
92
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin, M., Cao, Y., Greten, F. R., and Li, Z. W. (2002) NF-kappaB in cancer: from innocent bystander to major culprit. Nat. Rev. Cancer 2, 301-310.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
93
-
-
0027400286
-
Nuclear uptake control of NF-kappaB by MAD-3, an IkappaB protein present in the nucleus
-
Zabel, U., Henkel, T., Silva, M. S., and Baeuerle, P. A. (1993) Nuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleus. EMBO J. 12, 201-211. (Pubitemid 23042397)
-
(1993)
EMBO Journal
, vol.12
, Issue.1
, pp. 201-211
-
-
Zabel, U.1
Henkel, T.2
Dos Santos Silva, M.3
Baeuerle, P.A.4
-
94
-
-
0027078835
-
I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding
-
Ganchi, P. A., Sun, S. C., Greene, W. C., and Ballard, D. W. (1992) I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding. Mol. Biol. Cell 3, 1339-1352.
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 1339-1352
-
-
Ganchi, P.A.1
Sun, S.C.2
Greene, W.C.3
Ballard, D.W.4
-
95
-
-
0026783210
-
I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: A mechanism for cytoplasmic retention
-
Beg, A. A., Ruben, S. M., Scheinman, R. I., Haskill, S., Rosen, C. A., and Baldwin, A. S., Jr. (1992) I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention. Genes Dev. 6, 1899-1913.
-
(1992)
Genes Dev
, vol.6
, pp. 1899-1913
-
-
Beg, A.A.1
Ruben, S.M.2
Scheinman, R.I.3
Haskill, S.4
Rosen, C.A.5
Baldwin Jr., A.S.6
-
96
-
-
0027176524
-
Rapid proteolysis of IkappaB-alpha is necessary for activation of transcription factor NF-kappab
-
DOI 10.1038/365182a0
-
Henkel, T., Machleidt, T., Alkalay, I., Kronke, M., Ben-Neriah, Y., and Baeuerle, P. A. (1993) Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B. Nature 365, 182-185. (Pubitemid 23282067)
-
(1993)
Nature
, vol.365
, Issue.6442
, pp. 182-185
-
-
Henkel, T.1
Machleidt, T.2
Alkalay, I.3
Kronke, M.4
Ben-Neriah, Y.5
Baeuerle, P.A.6
-
97
-
-
0028148227
-
A proteasome inhibitor prevents activation of NF-kappaB and stabilizes a newly phosphorylated form of IkappaB-alpha that is still bound to NF-kappaB
-
Traenckner, E. B., Wilk, S., and Baeuerle, P. A. (1994) A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NFkappa B. EMBO J. 13, 5433-5441. (Pubitemid 24351822)
-
(1994)
EMBO Journal
, vol.13
, Issue.22
, pp. 5433-5441
-
-
Traenckner, E.B.-M.1
Wilk, S.2
Baeuerle, P.A.3
-
98
-
-
0023821516
-
Identification of a putative regulator of early T cell activation genes
-
Shaw, J. P., Utz, P. J., Durand, D. B., Toole, J. J., Emmel, E. A., and Crabtree, G. R. (1988) Identification of a putative regulator of early T cell activation genes. Science 241, 202-205.
-
(1988)
Science
, vol.241
, pp. 202-205
-
-
Shaw, J.P.1
Utz, P.J.2
Durand, D.B.3
Toole, J.J.4
Emmel, E.A.5
Crabtree, G.R.6
-
99
-
-
0030899131
-
Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin- Sensitive intramolecular interaction
-
Beals, C. R., Clipstone, N. A., Ho, S. N., and Crabtree, G. R. (1997) Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin- sensitive intramolecular interaction. Genes Dev. 11, 824-834.
-
(1997)
Genes Dev
, vol.11
, pp. 824-834
-
-
Beals, C.R.1
Clipstone, N.A.2
Ho, S.N.3
Crabtree, G.R.4
-
100
-
-
0032577673
-
Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1
-
DOI 10.1016/S0092-8674(00)81445-2
-
Zhu, J., Shibasaki, F., Price, R., Guillemot, J. C., Yano, T., Dotsch, V., Wagner, G., Ferrara, P., and McKeon, F. (1998) Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1. Cell 93, 851-861. (Pubitemid 28257590)
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 851-861
-
-
Zhu, J.1
Shibasaki, F.2
Price, R.3
Guillemot, J.-C.4
Yano, T.5
Dotsch, V.6
Wagner, G.7
Ferrara, P.8
McKeon, F.9
-
101
-
-
0034003578
-
Nucleocytoplasmic shuttling and the control of NF-AT signaling
-
Zhu, J. and McKeon, F. (2000) Nucleocytoplasmic shuttling and the control of NF-AT signaling. Cell Mol. Life Sci. 57, 411-420.
-
(2000)
Cell Mol. Life Sci.
, vol.57
, pp. 411-420
-
-
Zhu, J.1
McKeon, F.2
-
102
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275, 1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittmann, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
103
-
-
14444269482
-
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines
-
Teng, D. H.-F., Hu, R., Lin, H., Davis, T., Iliev, D., Frye, C., Swedlund, B., Hansen, K. L., Vinson, V. L., Gumpper, K. L., Ellis, L., El- Naggar, A., Frazier, M., Jasser, S., Langford, L. A., Lee, J., Mills, G. B., Perhouse, M. A., Pollack, R. E., Tornos, C., Troncoso, P., Yung, W. K. A., Fujii, G., Berson, A., Bookstein, R., Bolen, J. B., Tavtigian, S. V., Steck, P. A. (1997) MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res. 57, 5221-5225.
-
(1997)
Cancer Res
, vol.57
, pp. 5221-5225
-
-
Teng, D.H.-F.1
Hu, R.2
Lin, H.3
Davis, T.4
Iliev, D.5
Frye, C.6
Swedlund, B.7
Hansen, K.L.8
Vinson, V.L.9
Gumpper, K.L.10
Ellis, L.11
El- Naggar, A.12
Frazier, M.13
Jasser, S.14
Langford, L.A.15
Lee, J.16
Mills, G.B.17
Perhouse, M.A.18
Pollack, R.E.19
Tornos, C.20
Troncoso, P.21
Yung, W.K.A.22
Fujii, G.23
Berson, A.24
Bookstein, R.25
Bolen, J.B.26
Tavtigian, S.V.27
Steck, P.A.28
more..
-
104
-
-
0033852872
-
Mutations of the human PTEN gene
-
Bonneau, D. and Longy, M. (2000) Mutations of the human PTEN gene. Hum. Mutat. 16, 109-122.
-
(2000)
Hum. Mutat.
, vol.16
, pp. 109-122
-
-
Bonneau, D.1
Longy, M.2
-
105
-
-
0032577699
-
The tumor suppressor, PTEN/ MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama, T. and Dixon, J.E. (1998) The tumor suppressor, PTEN/ MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273, 13375-13378.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
106
-
-
27844535741
-
Class reunion: PTEN joins the nuclear crew
-
DOI 10.1038/sj.onc.1209089, PII 1209089
-
Lian, Z. and Di Cristofano, A. (2005) Class reunion: PTEN joins the nuclear crew. Oncogene 24, 7394-7400. (Pubitemid 41637979)
-
(2005)
Oncogene
, vol.24
, Issue.50
, pp. 7394-7400
-
-
Lian, Z.1
Di Cristofano, A.2
-
107
-
-
33845977965
-
Ubiquitination regulates PTEN nuclear import and tumor suppression
-
Trotman, L. C., Wang, X., Alimonti, A., Chen, Z., Teruya-Feldstein, J., Yang, H., Pavletich, N. P., Carver, B. S., Cordon-Cardo, C., Erdjument- Bromage, H., et al. (2007) Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell 128, 141-156.
-
(2007)
Cell
, vol.128
, pp. 141-156
-
-
Trotman, L.C.1
Wang, X.2
Alimonti, A.3
Chen, Z.4
Teruya-Feldstein, J.5
Yang, H.6
Pavletich, N.P.7
Carver, B.S.8
Cordon-Cardo, C.9
Erdjument- Bromage, H.10
-
108
-
-
0041742215
-
Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley- Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway
-
Zhou, X. P., Waite, K. A., Pilarski, R., Hampel, H., Fernandez, M. J., Bos, C., Dasouki, M., Feldman, G. L., Greenberg, L. A., Ivanovich, J., et al. (2003) Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley- Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway. Am. J. Hum. Genet. 73, 404-411.
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 404-411
-
-
Zhou, X.P.1
Waite, K.A.2
Pilarski, R.3
Hampel, H.4
Fernandez, M.J.5
Bos, C.6
Dasouki, M.7
Feldman, G.L.8
Greenberg, L.A.9
Ivanovich, J.10
|