Differential effects of CpG DNA on IFN-β induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages

Journal of Immunology

Volumn 179, Issue 6, 2007, Pages 3495-3503

  Schroder, Kate ^a   Spille, Martina ^b   Pilz, Andreas ^c   Lattin, Jane ^a   Bode, Konrad A ^b   Irvine, Katharine M ^a   Burrows, Allan D ^a   Ravasi, Timothy ^d   Weighardt, Heike ^e   Stacey, Katryn J ^a   Decker, Thomas ^c   Hume, David A ^a   Dalpke, Alexander H ^b   Sweet, Matthew J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c Vienna Biocenter   (Austria)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CPG DNA; CPG OLIGODEOXYNUCLEOTIDE; DNA; INTERFERON; INTERFERON REGULATORY FACTOR; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; SERINE; STAT1 PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR 9 INHIBITOR; TOLL LIKE RECEPTOR AGONIST; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; UNCLASSIFIED DRUG; IMMUNOLOGICAL ADJUVANT;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; ANIMAL; AUTOCRINE EFFECT; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; COMPARATIVE STUDY; CPG ISLAND; DOWN REGULATION; DRUG ANTAGONISM; FEMALE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; AUTOCRINE COMMUNICATION; CELL LINE; CPG ISLANDS; DENDRITIC CELLS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERFERON-BETA; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTORS;

EID: 35748939086     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.6.3495     Document Type: Article

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