-
1
-
-
0036558025
-
The SOCS box: A tale of destruction and degradation
-
Kile, B.T. et al. The SOCS box: a tale of destruction and degradation. Trends Biochem. Sci. 27, 235-241 (2002).
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 235-241
-
-
Kile, B.T.1
-
2
-
-
0032836015
-
Suppressors of cytokine signaling (SOCS): Negative regulators of signal transduction
-
Alexander, W.S. et al. Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction. J. Leukoc. Biol. 66, 588-592 (1999).
-
(1999)
J. Leukoc. Biol.
, vol.66
, pp. 588-592
-
-
Alexander, W.S.1
-
3
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon-γ signaling and prevents the potentially fatal neonatal actions of this cytokine
-
Alexander, W.S. et al. SOCS1 is a critical inhibitor of interferon-γ signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 98, 597-608 (1999).
-
(1999)
Cell
, vol.98
, pp. 597-608
-
-
Alexander, W.S.1
-
4
-
-
0033520467
-
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
-
Marine, J.C. et al. SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell 98, 609-616 (1999).
-
(1999)
Cell
, vol.98
, pp. 609-616
-
-
Marine, J.C.1
-
5
-
-
0034729710
-
Gigantism in mice lacking suppressor of cytolkine signalling-2
-
Metcalf, D. et al. Gigantism in mice lacking suppressor of cytolkine signalling-2. Nature 405, 1069-1073 (2000).
-
(2000)
Nature
, vol.405
, pp. 1069-1073
-
-
Metcalf, D.1
-
6
-
-
0037174816
-
Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling
-
Greenhalgh, C.J. et al. Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling. J. Biol. Chem. 277, 40181-40184 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40181-40184
-
-
Greenhalgh, C.J.1
-
7
-
-
0033520389
-
SOCS3 is essential in the regulation of fetal liver erythropoiesis
-
Marine, J.C. et al. SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell 98, 617-627 (1999).
-
(1999)
Cell
, vol.98
, pp. 617-627
-
-
Marine, J.C.1
-
8
-
-
0037415694
-
SOCS3: An essential regulator of LIF receptor signaling in trophoblast giant cell differentiation
-
Takahashi, Y. et al. SOCS3: An essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. EMBO J. 22, 372-384 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 372-384
-
-
Takahashi, Y.1
-
9
-
-
0035979275
-
Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3
-
Roberts, A.W. et al. Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3. Proc. Natl. Acad. Sci. USA 98, 9324-9329 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9324-9329
-
-
Roberts, A.W.1
-
10
-
-
0037162397
-
SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities
-
De Souza, D. et al. SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities. Biochemistry 41, 9229-9236 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 9229-9236
-
-
De Souza, D.1
-
11
-
-
0034724677
-
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
-
Schmitz, J. et al. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. J. Biol. Chem. 275, 12848-12856 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12848-12856
-
-
Schmitz, J.1
-
12
-
-
0034612271
-
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp13O
-
Nicholson, S.E. et al. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp13O. Proc. Natl. Acad, Sci. USA 97, 6493-6498 (2000).
-
(2000)
Proc. Natl. Acad, Sci. USA
, vol.97
, pp. 6493-6498
-
-
Nicholson, S.E.1
-
13
-
-
0036681955
-
Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
-
Hortner, M. et al. Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. J. Immunol. 169, 1219-1227 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 1219-1227
-
-
Hortner, M.1
-
14
-
-
0036105755
-
A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor
-
Hortner, M. et al. A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor. Eur. J. Biochem. 269, 2516-2526 (2002).
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 2516-2526
-
-
Hortner, M.1
-
15
-
-
0033535958
-
Autoregulation of pituitary corticotroph SOCS-3 expression: Characterization of the murine SOCS-3 promoter
-
Auernhammer, C.J., Bousquet, C. & Melmed, S. Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter. Proc. Natl. Acad. Sci. USA 96, 6964-6969 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6964-6969
-
-
Auernhammer, C.J.1
Bousquet, C.2
Melmed, S.3
-
16
-
-
13044290651
-
Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: Evidence for an IL-10-induced pathway that is independent of STAT protein activation
-
Cassatella, M.A, et al. Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: evidence for an IL-10-induced pathway that is independent of STAT protein activation. Blood 94, 2880-2889 (1999).
-
(1999)
Blood
, vol.94
, pp. 2880-2889
-
-
Cassatella, M.A.1
-
17
-
-
0033197958
-
Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-γ
-
Stoiber, D. et al. Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-γ. J. Immunol. 163, 2640-2647 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 2640-2647
-
-
Stoiber, D.1
-
18
-
-
0035159504
-
Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3
-
Stoiber, D. et al. Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3. J. Immunol. 166, 466-472 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 466-472
-
-
Stoiber, D.1
-
19
-
-
0033233214
-
LIPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages
-
Bode, J.G. et al. LIPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett. 463, 365-370 (1999).
-
(1999)
FEBS Lett.
, vol.463
, pp. 365-370
-
-
Bode, J.G.1
-
20
-
-
0035877256
-
Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs
-
Dalpke, A.H., Opper, S., Zimmermann, S. & Heeg, K. Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs. J. Immunol. 166, 7082-7089 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 7082-7089
-
-
Dalpke, A.H.1
Opper, S.2
Zimmermann, S.3
Heeg, K.4
-
21
-
-
0035667907
-
Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis
-
Shouda, T. et al. Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. J. Clin. Invest. 108, 1781-1788 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1781-1788
-
-
Shouda, T.1
-
22
-
-
0035910753
-
CIS3/SOCS3/SS13 plays a negative regulatory role in STAT3 activation and intestinal inflammation
-
Suzuki, A. et al. CIS3/SOCS3/SS13 plays a negative regulatory role in STAT3 activation and intestinal inflammation. J. Exp. Med. 193, 471-481 (2001).
-
(2001)
J. Exp. Med.
, vol.193
, pp. 471-481
-
-
Suzuki, A.1
-
23
-
-
0037097509
-
Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation
-
Berlato, C. et al. Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation. J. Immunol. 168, 6404-6411 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 6404-6411
-
-
Berlato, C.1
-
24
-
-
0032779561
-
The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes
-
Donnelly, R.P., Dickensheets, H. & Finbloom, D.S. The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J. Interferon Cytokine Res. 19, 563-573 (1999).
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 563-573
-
-
Donnelly, R.P.1
Dickensheets, H.2
Finbloom, D.S.3
-
25
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich, P.C. et al. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 334, 297-314 (1998).
-
(1998)
Biochem. J.
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
-
26
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
Takeda, K. et al. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10, 39-49 (1999).
-
(1999)
Immunity
, vol.10
, pp. 39-49
-
-
Takeda, K.1
-
27
-
-
0036721716
-
Shaping gene expression in activated and resting primary macrophages by IL-10
-
Lang, R, et al. Shaping gene expression in activated and resting primary macrophages by IL-10. J. Immunol. 169, 2253-2263 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 2253-2263
-
-
Lang, R.1
-
28
-
-
0034977353
-
Functional classification of interferon-stimulated genes identified using microarrays
-
de Veer, M.J. et al. Functional classification of interferon-stimulated genes identified using microarrays. J. Leukoc. Biol. 69, 912-920 (2001).
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 912-920
-
-
de Veer, M.J.1
-
29
-
-
0035666295
-
Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited
-
Friederichs, K. et al. Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited. Eur. J. Biochem. 268, 6401-6407 (2001).
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 6401-6407
-
-
Friederichs, K.1
-
30
-
-
0001903105
-
Dissection of signaling cascades through gp130 in vivo: Reciprocal roles for STAT3- and SHP2-mediated signals in immune responses
-
Ohtani, T. et al. Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. Immunity 12, 95-105 (2000).
-
(2000)
Immunity
, vol.12
, pp. 95-105
-
-
Ohtani, T.1
-
31
-
-
0036796060
-
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
-
Tebbutt, N.C. et al. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nat. Med. 8, 1089-1097 (2002).
-
(2002)
Nat. Med.
, vol.8
, pp. 1089-1097
-
-
Tebbutt, N.C.1
-
32
-
-
0035006109
-
Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 rasGAP and activates Ras
-
Cacalano, N.A., Sanden, D. & Johnson, J.A. Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 rasGAP and activates Ras. Nat. Cell Biol. 3, 460-465 (2001).
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 460-465
-
-
Cacalano, N.A.1
Sanden, D.2
Johnson, J.A.3
-
33
-
-
0037062503
-
Mutational switch of an IL-6 response to an interferon-γ-like response
-
Costa-Pereira, A.P. et al. Mutational switch of an IL-6 response to an interferon-γ-like response. Proc. Natl. Acad. Sci. USA 99, 8043-8047 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8043-8047
-
-
Costa-Pereira, A.P.1
-
34
-
-
0034515268
-
Immune response in Stat2 knockout mice
-
Park, C., Li, E., Cha, E. & Schindler, C. Immune response in Stat2 knockout mice. Immunity 13, 795-804 (2000).
-
(2000)
Immunity
, vol.13
, pp. 795-804
-
-
Park, C.1
Li, E.2
Cha, E.3
Schindler, C.4
-
35
-
-
0037938816
-
SOCS3 negatively regulates IL-6 signaling in vivo
-
advance online publication, 18 May (doi:10.1038/ni931)
-
Croker, B.A. et al. SOCS3 negatively regulates IL-6 signaling in vivo. Nat. Immunol, advance online publication, 18 May 2003 (doi:10.1038/ni931).
-
(2003)
Nat. Immunol.
-
-
Croker, B.A.1
|