메뉴 건너뛰기




Volumn , Issue , 2010, Pages 569-597

NK-2 Class Homeodomain Proteins. Conserved Regulators of Cardiogenesis

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84858822989     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-381332-9.00026-8     Document Type: Chapter
Times cited : (17)

References (216)
  • 1
    • 0038782391 scopus 로고    scopus 로고
    • Pannier and pointedP2 act sequentially to regulate Drosophila heart development
    • Alvarez A.D., Shi W., Wilson B.A., Skeath J.B. Pannier and pointedP2 act sequentially to regulate Drosophila heart development. Development 2003, 130:3015-3026.
    • (2003) Development , vol.130 , pp. 3015-3026
    • Alvarez, A.D.1    Shi, W.2    Wilson, B.A.3    Skeath, J.B.4
  • 2
    • 0027237596 scopus 로고
    • Tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
    • Azpiazu N., Frasch M. Tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 1993, 7:1325-1340.
    • (1993) Genes Dev. , vol.7 , pp. 1325-1340
    • Azpiazu, N.1    Frasch, M.2
  • 3
    • 34247632152 scopus 로고    scopus 로고
    • Stem cells and the regeneration of the aging cardiovascular system
    • Ballard V.L., Edelberg J.M. Stem cells and the regeneration of the aging cardiovascular system. Circ. Res. 2007, 100:1116-1127.
    • (2007) Circ. Res. , vol.100 , pp. 1116-1127
    • Ballard, V.L.1    Edelberg, J.M.2
  • 4
    • 34548818514 scopus 로고    scopus 로고
    • Transient early embryonic expression of Nkx2-5 mutations linked to congenital heart defects in human cause heart defects in Xenopus laevis
    • Bartlett H.L., Sutherland L., Kolker S.J., Welp C., Tajchman U., Desmarais V., Weeks D.L. Transient early embryonic expression of Nkx2-5 mutations linked to congenital heart defects in human cause heart defects in Xenopus laevis. Dev. Dyn. 2007, 236:2475-2484.
    • (2007) Dev. Dyn. , vol.236 , pp. 2475-2484
    • Bartlett, H.L.1    Sutherland, L.2    Kolker, S.J.3    Welp, C.4    Tajchman, U.5    Desmarais, V.6    Weeks, D.L.7
  • 10
    • 0030926451 scopus 로고    scopus 로고
    • Homeodomain factor Nkx2-5 controls left-right asymmetric expression of bHLH eHand during murine heart development
    • Biben C., Harvey R.P. Homeodomain factor Nkx2-5 controls left-right asymmetric expression of bHLH eHand during murine heart development. Genes Dev. 1997, 11:1357-1369.
    • (1997) Genes Dev. , vol.11 , pp. 1357-1369
    • Biben, C.1    Harvey, R.P.2
  • 11
    • 0031959594 scopus 로고    scopus 로고
    • Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart
    • Biben C., Hatzistavrou T., Harvey R.P. Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart. Mech. Dev. 1998, 73:125-127.
    • (1998) Mech. Dev. , vol.73 , pp. 125-127
    • Biben, C.1    Hatzistavrou, T.2    Harvey, R.P.3
  • 13
    • 0027282774 scopus 로고
    • The gene tinman is required for specification of the heart and visceral muscles in Drosophila
    • Bodmer R. The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 1993, 118:719-729.
    • (1993) Development , vol.118 , pp. 719-729
    • Bodmer, R.1
  • 14
    • 0028959673 scopus 로고
    • Heart development in Drosophila and its relationship to vertebrates
    • Bodmer R. Heart development in Drosophila and its relationship to vertebrates. Trends Cardiovasc. Med. 1995, 5:21-28.
    • (1995) Trends Cardiovasc. Med. , vol.5 , pp. 21-28
    • Bodmer, R.1
  • 15
    • 0002453643 scopus 로고    scopus 로고
    • Genetic determination of Drosophila heart development
    • Academic Press, San Diego, CA, R. Harvey, N. Rosenthal (Eds.)
    • Bodmer R., Frasch M. Genetic determination of Drosophila heart development. Heart Development 1999, 65-90. Academic Press, San Diego, CA. R. Harvey, N. Rosenthal (Eds.).
    • (1999) Heart Development , pp. 65-90
    • Bodmer, R.1    Frasch, M.2
  • 16
    • 0037077285 scopus 로고    scopus 로고
    • A novel family of calmodulin-binding transcription activators in multicellular organisms
    • Bouche N., Scharlat A., Snedden W., Bouchez D., Fromm H. A novel family of calmodulin-binding transcription activators in multicellular organisms. J. Biol. Chem. 2002, 277:21851-21861.
    • (2002) J. Biol. Chem. , vol.277 , pp. 21851-21861
    • Bouche, N.1    Scharlat, A.2    Snedden, W.3    Bouchez, D.4    Fromm, H.5
  • 17
    • 1642402120 scopus 로고    scopus 로고
    • The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer
    • Brown C.O., Chi X., Garcia-Gras E., Shirai M., Feng X.H., Schwartz R.J. The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J. Biol. Chem. 2004, 279:10659-10669.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10659-10669
    • Brown, C.O.1    Chi, X.2    Garcia-Gras, E.3    Shirai, M.4    Feng, X.H.5    Schwartz, R.J.6
  • 19
    • 0035879219 scopus 로고    scopus 로고
    • Novel cell lines promote the discovery of genes involved in early heart development
    • Brunskill E.W., Witte D.P., Yutzey K.E., Potter S.S. Novel cell lines promote the discovery of genes involved in early heart development. Dev. Biol. 2001, 235:507-520.
    • (2001) Dev. Biol. , vol.235 , pp. 507-520
    • Brunskill, E.W.1    Witte, D.P.2    Yutzey, K.E.3    Potter, S.S.4
  • 20
    • 0029984771 scopus 로고    scopus 로고
    • Chick NKx-2.3 represents a novel family member of vertebrate homologues to Drosophila homeobox gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development
    • Buchberger A., Pabst O., Brand T., Seidl K., Arnold H.-H. Chick NKx-2.3 represents a novel family member of vertebrate homologues to Drosophila homeobox gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development. Mech. Dev. 1996, 56:151-163.
    • (1996) Mech. Dev. , vol.56 , pp. 151-163
    • Buchberger, A.1    Pabst, O.2    Brand, T.3    Seidl, K.4    Arnold, H.-H.5
  • 21
    • 33644680809 scopus 로고    scopus 로고
    • Building the mammalian heart from two sources of myocardial cells
    • Buckingham M., Meilhac S., Zaffran S. Building the mammalian heart from two sources of myocardial cells. Nat. Rev. Genet. 2005, 6:826-835.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 826-835
    • Buckingham, M.1    Meilhac, S.2    Zaffran, S.3
  • 22
    • 0346783332 scopus 로고    scopus 로고
    • Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart
    • Cai C.L., Liang X., Shi Y., Chu P.H., Pfaff S.L., Chen J., Evans S. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev. Cell. 2003, 5:877-889.
    • (2003) Dev. Cell. , vol.5 , pp. 877-889
    • Cai, C.L.1    Liang, X.2    Shi, Y.3    Chu, P.H.4    Pfaff, S.L.5    Chen, J.6    Evans, S.7
  • 23
    • 0029046714 scopus 로고
    • Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, Nkx-2.5
    • Chen C.Y., Schwartz R.J. Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, Nkx-2.5. J. Biol. Chem. 1995, 270:15628-15633.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15628-15633
    • Chen, C.Y.1    Schwartz, R.J.2
  • 24
    • 0000634381 scopus 로고    scopus 로고
    • Recruitment of the tinman homologue Nkx-2.5 by serum response factor activates cardiac a-actin gene transcription
    • Chen C.Y., Schwartz R.J. Recruitment of the tinman homologue Nkx-2.5 by serum response factor activates cardiac a-actin gene transcription. Mol. Cell. Biol. 1996, 16:6372-6384.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6372-6384
    • Chen, C.Y.1    Schwartz, R.J.2
  • 25
    • 0000342273 scopus 로고    scopus 로고
    • Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements
    • Chen C.Y., Croissant J., Majesky M., Topouzis S., McQuinn T., Frankovsky M.J., Schwartz R.J. Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements. Dev. Genet. 1996, 19:119-130.
    • (1996) Dev. Genet. , vol.19 , pp. 119-130
    • Chen, C.Y.1    Croissant, J.2    Majesky, M.3    Topouzis, S.4    McQuinn, T.5    Frankovsky, M.J.6    Schwartz, R.J.7
  • 27
    • 0030465318 scopus 로고    scopus 로고
    • Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation
    • Chen J.N., Fishman M.C. Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 1996, 122:3809-3816.
    • (1996) Development , vol.122 , pp. 3809-3816
    • Chen, J.N.1    Fishman, M.C.2
  • 28
    • 26444593024 scopus 로고    scopus 로고
    • Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules
    • Chi X., Chatterjee P.K., Wilson W., Zhang S.X., Demayo F.J., Schwartz R.J. Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules. Proc. Natl. Acad. Sci. USA 2005, 102:13490-13495.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 13490-13495
    • Chi, X.1    Chatterjee, P.K.2    Wilson, W.3    Zhang, S.X.4    Demayo, F.J.5    Schwartz, R.J.6
  • 29
    • 0000338572 scopus 로고    scopus 로고
    • The homeodomain transcription factor NK-4 acts as either a transcriptional activator or repressor and interacts with the p300 coactivator and the groucho corepressor
    • Choi C.Y., Lee Y.M., Kim Y.H., Park T., Jeon B.H., Schulz R.A., Kim Y. The homeodomain transcription factor NK-4 acts as either a transcriptional activator or repressor and interacts with the p300 coactivator and the groucho corepressor. J. Biol. Chem. 1999, 274:31543-31552.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31543-31552
    • Choi, C.Y.1    Lee, Y.M.2    Kim, Y.H.3    Park, T.4    Jeon, B.H.5    Schulz, R.A.6    Kim, Y.7
  • 32
    • 40549132870 scopus 로고    scopus 로고
    • Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes
    • Christoforou N., Miller R.A., Hill C.M., Jie C.C., Mccallion A.S., Gearhart J.D. Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes. J. Clin. Invest. 2008, 118:894-903.
    • (2008) J. Clin. Invest. , vol.118 , pp. 894-903
    • Christoforou, N.1    Miller, R.A.2    Hill, C.M.3    Jie, C.C.4    Mccallion, A.S.5    Gearhart, J.D.6
  • 33
    • 0029955134 scopus 로고    scopus 로고
    • Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia
    • Cleaver O.B., Patterson K.D., Krieg P.A. Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia. Development 1996, 122:3549-3556.
    • (1996) Development , vol.122 , pp. 3549-3556
    • Cleaver, O.B.1    Patterson, K.D.2    Krieg, P.A.3
  • 34
    • 28844446200 scopus 로고    scopus 로고
    • The EH1 motif in metazoan transcription factors
    • Copley R.R. The EH1 motif in metazoan transcription factors. BMC Genomics 2005, 6:169.
    • (2005) BMC Genomics , vol.6 , pp. 169
    • Copley, R.R.1
  • 35
    • 0036608009 scopus 로고    scopus 로고
    • Control of cardiac development by an evolutionarily conserved transcriptional network
    • Cripps R.M., Olson E.N. Control of cardiac development by an evolutionarily conserved transcriptional network. Dev. Biol. 2002, 246:14-28.
    • (2002) Dev. Biol. , vol.246 , pp. 14-28
    • Cripps, R.M.1    Olson, E.N.2
  • 37
    • 32444446240 scopus 로고    scopus 로고
    • Gene regulatory networks and the evolution of animal body plans
    • Davidson E.H., Erwin D.H. Gene regulatory networks and the evolution of animal body plans. Science 2006, 311:796-800.
    • (2006) Science , vol.311 , pp. 796-800
    • Davidson, E.H.1    Erwin, D.H.2
  • 38
    • 0028972715 scopus 로고
    • Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression
    • Dawson S.R., Turner D.L., Weintraub H., Parkhurst S.M. Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression. Mol. Cell Biol. 1995, 15:6923-6931.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 6923-6931
    • Dawson, S.R.1    Turner, D.L.2    Weintraub, H.3    Parkhurst, S.M.4
  • 39
    • 5444271023 scopus 로고    scopus 로고
    • Thyroid development and its disorders: genetics and molecular mechanisms
    • De Felice M., Di Lauro R. Thyroid development and its disorders: genetics and molecular mechanisms. Endocr. Rev. 2004, 25:722-746.
    • (2004) Endocr. Rev. , vol.25 , pp. 722-746
    • De Felice, M.1    Di Lauro, R.2
  • 41
    • 4544236360 scopus 로고    scopus 로고
    • Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development
    • Dodou E., Verzi M.P., Anderson J.P., Xu S.M., Black B.L. Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development. Development 2004, 131:3931-3942.
    • (2004) Development , vol.131 , pp. 3931-3942
    • Dodou, E.1    Verzi, M.P.2    Anderson, J.P.3    Xu, S.M.4    Black, B.L.5
  • 43
    • 0030799792 scopus 로고    scopus 로고
    • The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
    • Durocher D., Charron F., Warren R., Schwartz R.J., Nemer M. The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO. J. 1997, 16:5687-5696.
    • (1997) EMBO. J. , vol.16 , pp. 5687-5696
    • Durocher, D.1    Charron, F.2    Warren, R.3    Schwartz, R.J.4    Nemer, M.5
  • 44
    • 0029779002 scopus 로고    scopus 로고
    • The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium
    • Durocher D., Chen C.-Y., Ardati A., Schwartz R.J., Nemer M. The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium. Mol. Cell Biol. 1996, 16:4648-4655.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4648-4655
    • Durocher, D.1    Chen, C.-Y.2    Ardati, A.3    Schwartz, R.J.4    Nemer, M.5
  • 46
    • 33646149991 scopus 로고    scopus 로고
    • A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery
    • Elliott D.A., Solloway M.J., Wise N., Biben C., Costa M.W., Furtado M.B., Lange M., Dunwoodie S., Harvey R.P. A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery. Development 2006, 133:1311-1322.
    • (2006) Development , vol.133 , pp. 1311-1322
    • Elliott, D.A.1    Solloway, M.J.2    Wise, N.3    Biben, C.4    Costa, M.W.5    Furtado, M.B.6    Lange, M.7    Dunwoodie, S.8    Harvey, R.P.9
  • 47
    • 0033072866 scopus 로고    scopus 로고
    • Vertebrate tinman homologues and cardiac differentiation
    • Evans S. Vertebrate tinman homologues and cardiac differentiation. Sem. Cell Dev. Biol. 1999, 10:73-83.
    • (1999) Sem. Cell Dev. Biol. , vol.10 , pp. 73-83
    • Evans, S.1
  • 48
    • 0028863326 scopus 로고
    • Tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second homologue of tinman
    • Evans S., Yan W., Murillo M.P., Ponce J., Papalopulu N. Tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second homologue of tinman. Development 1995, 121:3889-3899.
    • (1995) Development , vol.121 , pp. 3889-3899
    • Evans, S.1    Yan, W.2    Murillo, M.P.3    Ponce, J.4    Papalopulu, N.5
  • 50
    • 0031882143 scopus 로고    scopus 로고
    • Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1
    • Firulli A.B., Mcfadden D.G., Lin Q., Srivastava D., Olson E.N. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat. Genet. 1998, 18:266-270.
    • (1998) Nat. Genet. , vol.18 , pp. 266-270
    • Firulli, A.B.1    Mcfadden, D.G.2    Lin, Q.3    Srivastava, D.4    Olson, E.N.5
  • 51
    • 0030010697 scopus 로고    scopus 로고
    • The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain
    • Fisher A.L., Ohsako S., Caudy M. The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain. Mol. Cell Biol. 1996, 16:2670-2677.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 2670-2677
    • Fisher, A.L.1    Ohsako, S.2    Caudy, M.3
  • 52
    • 0031851485 scopus 로고    scopus 로고
    • Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex
    • Fraenkel E., Pabo C.O. Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex. Nat. Struct. Biol. 1998, 5:692-697.
    • (1998) Nat. Struct. Biol. , vol.5 , pp. 692-697
    • Fraenkel, E.1    Pabo, C.O.2
  • 53
    • 0038640316 scopus 로고    scopus 로고
    • The role of Pitx2 during cardiac development. Linking left-right signaling and congenital heart diseases
    • Franco D., Campione M. The role of Pitx2 during cardiac development. Linking left-right signaling and congenital heart diseases. Trends Cardiovasc. Med. 2003, 13:157-163.
    • (2003) Trends Cardiovasc. Med. , vol.13 , pp. 157-163
    • Franco, D.1    Campione, M.2
  • 54
    • 0033071157 scopus 로고    scopus 로고
    • Intersecting signalling and transcriptional pathways in Drosophila heart specification
    • Frasch M. Intersecting signalling and transcriptional pathways in Drosophila heart specification. Semin. Cell Dev. Biol. 1999, 10:61-71.
    • (1999) Semin. Cell Dev. Biol. , vol.10 , pp. 61-71
    • Frasch, M.1
  • 55
    • 0029584055 scopus 로고
    • Cardiac myogenesis: overexpression of XCsx2 or XMef2a in whole Xenopus embryos induces the precocious expression of XMHCa gene
    • Fu Y., Izumo S. Cardiac myogenesis: overexpression of XCsx2 or XMef2a in whole Xenopus embryos induces the precocious expression of XMHCa gene. Roux's Arch. Dev. Biol. 1995, 205:198-202.
    • (1995) Roux's Arch. Dev. Biol. , vol.205 , pp. 198-202
    • Fu, Y.1    Izumo, S.2
  • 56
    • 0031647381 scopus 로고    scopus 로고
    • Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
    • Fu Y., Yan W., Mohun T.J., Evans S.M. Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner. Development 1998, 125:4439-4449.
    • (1998) Development , vol.125 , pp. 4439-4449
    • Fu, Y.1    Yan, W.2    Mohun, T.J.3    Evans, S.M.4
  • 57
    • 0031033603 scopus 로고    scopus 로고
    • D-mef2 is a target for Tinman activation during Drosophila heart development
    • Gajewski K., Kim Y., Lee Y.M., Olson E.N., Schulz R.A. D-mef2 is a target for Tinman activation during Drosophila heart development. EMBO. J. 1997, 16:515-522.
    • (1997) EMBO. J. , vol.16 , pp. 515-522
    • Gajewski, K.1    Kim, Y.2    Lee, Y.M.3    Olson, E.N.4    Schulz, R.A.5
  • 58
    • 0033398273 scopus 로고    scopus 로고
    • The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila
    • Gajewski K., Fossett N., Molkentin J.D., Schulz R.A. The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila. Development 1999, 126:5679-5688.
    • (1999) Development , vol.126 , pp. 5679-5688
    • Gajewski, K.1    Fossett, N.2    Molkentin, J.D.3    Schulz, R.A.4
  • 61
    • 24744435397 scopus 로고    scopus 로고
    • Mammalian Groucho homologs: redundancy or specificity?
    • Gasperowicz M., Otto F. Mammalian Groucho homologs: redundancy or specificity?. J. Cell Biochem. 2005, 95:670-687.
    • (2005) J. Cell Biochem. , vol.95 , pp. 670-687
    • Gasperowicz, M.1    Otto, F.2
  • 63
    • 0035923555 scopus 로고    scopus 로고
    • NKX2.5 mutations in patients with tetralogy of Fallot
    • Goldmuntz E., Geiger E., Benson D.W. NKX2.5 mutations in patients with tetralogy of Fallot. Circulation 2001, 104:2565-2568.
    • (2001) Circulation , vol.104 , pp. 2565-2568
    • Goldmuntz, E.1    Geiger, E.2    Benson, D.W.3
  • 64
    • 0028323421 scopus 로고
    • A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription
    • Grepin C., Dagnino L., Robitaille L., Haberstroh L., Antakly T., Nemer M. A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription. Mol. Cell Biol. 1994, 14:3115-3129.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 3115-3129
    • Grepin, C.1    Dagnino, L.2    Robitaille, L.3    Haberstroh, L.4    Antakly, T.5    Nemer, M.6
  • 65
    • 0032380010 scopus 로고    scopus 로고
    • Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5
    • Grow M.W., Krieg P.A. Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5. Dev. Biol. 1998, 204:187-196.
    • (1998) Dev. Biol. , vol.204 , pp. 187-196
    • Grow, M.W.1    Krieg, P.A.2
  • 66
    • 0030916275 scopus 로고    scopus 로고
    • Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity
    • Gruschus J., Tsao D., Wang L.-H., Nirenberg M., Ferretti J. Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry 1997, 36:5372-5380.
    • (1997) Biochemistry , vol.36 , pp. 5372-5380
    • Gruschus, J.1    Tsao, D.2    Wang, L.-H.3    Nirenberg, M.4    Ferretti, J.5
  • 67
    • 0033546260 scopus 로고    scopus 로고
    • The three dimensional structure of the vnd/NK-2 homeodomain-DNA complex by NMR spectroscopy
    • Gruschus J., Tsao D., Wang L.-H., Nirenberg M., Ferretti J. The three dimensional structure of the vnd/NK-2 homeodomain-DNA complex by NMR spectroscopy. J. Mol. Biol. 1999, 289:529-545.
    • (1999) J. Mol. Biol. , vol.289 , pp. 529-545
    • Gruschus, J.1    Tsao, D.2    Wang, L.-H.3    Nirenberg, M.4    Ferretti, J.5
  • 68
    • 0025010740 scopus 로고
    • Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity
    • Guazzi S., Price M., De Felice M., Damante G., Mattei M.-G., Di Lauro R. Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO. J. 1990, 9:3631-3639.
    • (1990) EMBO. J. , vol.9 , pp. 3631-3639
    • Guazzi, S.1    Price, M.2    De Felice, M.3    Damante, G.4    Mattei, M.-G.5    Di Lauro, R.6
  • 69
    • 0036631483 scopus 로고    scopus 로고
    • Progressive AV-block and anomalous venous return among cardiac anomalies associated with two novel missense mutations in the CSX/NKX2-5 gene
    • Gutierrez-Roelens I., Sluysmans T., Gewillig M., Devriendt K., Vikkula M. Progressive AV-block and anomalous venous return among cardiac anomalies associated with two novel missense mutations in the CSX/NKX2-5 gene. Hum. Mutat. 2002, 20:75-76.
    • (2002) Hum. Mutat. , vol.20 , pp. 75-76
    • Gutierrez-Roelens, I.1    Sluysmans, T.2    Gewillig, M.3    Devriendt, K.4    Vikkula, M.5
  • 70
  • 72
    • 24344440942 scopus 로고    scopus 로고
    • Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis
    • Han Z., Olson E.N. Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis. Development 2005, 132:3525-3536.
    • (2005) Development , vol.132 , pp. 3525-3536
    • Han, Z.1    Olson, E.N.2
  • 73
    • 0030587603 scopus 로고    scopus 로고
    • NK-2 homeobox genes and heart development
    • Harvey R.P. NK-2 homeobox genes and heart development. Dev. Biol. 1996, 178:203-216.
    • (1996) Dev. Biol. , vol.178 , pp. 203-216
    • Harvey, R.P.1
  • 74
    • 0002302912 scopus 로고    scopus 로고
    • Transcriptional control and pattern formation in the vertebrate heart: studies on NK-2 class homeodomain factors
    • Academic Press, San Diego, CA, R.P. Harvey, N. Rosenthal (Eds.)
    • Harvey R.P., Biben C., Elliott D.A. Transcriptional control and pattern formation in the vertebrate heart: studies on NK-2 class homeodomain factors. Heart Development 1998, 111-129. Academic Press, San Diego, CA. R.P. Harvey, N. Rosenthal (Eds.).
    • (1998) Heart Development , pp. 111-129
    • Harvey, R.P.1    Biben, C.2    Elliott, D.A.3
  • 77
    • 0034931034 scopus 로고    scopus 로고
    • Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
    • Hiroi Y., Kudoh S., Monzen K., Ikeda Y., Yazaki Y., Nagai R., Komuro I. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat. Genet. 2001, 28:276-280.
    • (2001) Nat. Genet. , vol.28 , pp. 276-280
    • Hiroi, Y.1    Kudoh, S.2    Monzen, K.3    Ikeda, Y.4    Yazaki, Y.5    Nagai, R.6    Komuro, I.7
  • 78
    • 0037134945 scopus 로고    scopus 로고
    • The incidence of congenital heart disease
    • Hoffman J.I., Kaplan S. The incidence of congenital heart disease. J. Am. Coll. Cardiol. 2002, 39:1890-1900.
    • (2002) J. Am. Coll. Cardiol. , vol.39 , pp. 1890-1900
    • Hoffman, J.I.1    Kaplan, S.2
  • 80
    • 33751160409 scopus 로고    scopus 로고
    • ID proteins as targets in cancer and tools in neurobiology
    • Iavarone A., Lasorella A. ID proteins as targets in cancer and tools in neurobiology. Trends Mol. Med. 2006, 12:588-594.
    • (2006) Trends Mol. Med. , vol.12 , pp. 588-594
    • Iavarone, A.1    Lasorella, A.2
  • 83
    • 33645238760 scopus 로고    scopus 로고
    • Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals
    • Isono K., Nemoto K., Li Y., Takada Y., Suzuki R., Katsuki M., Nakagawara A., Koseki H. Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol. Cell Biol. 2006, 26:2758-2771.
    • (2006) Mol. Cell Biol. , vol.26 , pp. 2758-2771
    • Isono, K.1    Nemoto, K.2    Li, Y.3    Takada, Y.4    Suzuki, R.5    Katsuki, M.6    Nakagawara, A.7    Koseki, H.8
  • 85
    • 0032959891 scopus 로고    scopus 로고
    • Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tissue specifying homeobox gene product Csx/Nkx2-5
    • Kasahara H., Izumo S. Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tissue specifying homeobox gene product Csx/Nkx2-5. Mol. Cell Biol. 1999, 19:526-536.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 526-536
    • Kasahara, H.1    Izumo, S.2
  • 86
    • 0033912859 scopus 로고    scopus 로고
    • Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease
    • Kasahara H., Lee B., Schott J.J., Benson D.W., Seidman J.G., Seidman C.E., Izumo S. Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease. J. Clin. Invest. 2000, 106:299-308.
    • (2000) J. Clin. Invest. , vol.106 , pp. 299-308
    • Kasahara, H.1    Lee, B.2    Schott, J.J.3    Benson, D.W.4    Seidman, J.G.5    Seidman, C.E.6    Izumo, S.7
  • 88
    • 4444223413 scopus 로고    scopus 로고
    • Biochemical analyses of eight NKX2.5 homeodomain missense mutations causing atrioventricular block and cardiac anomalies
    • Kasahara H., Benson D.W. Biochemical analyses of eight NKX2.5 homeodomain missense mutations causing atrioventricular block and cardiac anomalies. Cardiovasc. Res. 2004, 64:40-51.
    • (2004) Cardiovasc. Res. , vol.64 , pp. 40-51
    • Kasahara, H.1    Benson, D.W.2
  • 89
    • 33750456216 scopus 로고    scopus 로고
    • Multipotent flk-1+ cardio-vascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages
    • Kattman S.J., Huber T.L., Keller G.M. Multipotent flk-1+ cardio-vascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev. Cell 2006, 11:723-732.
    • (2006) Dev. Cell , vol.11 , pp. 723-732
    • Kattman, S.J.1    Huber, T.L.2    Keller, G.M.3
  • 90
    • 0018970109 scopus 로고
    • Cytogenetic analysis of chromosome 3 in Drosophila melanogaster: the homeotic gene complex in polytene chromosome interval 84A-B
    • Kaufman T.C., Lewis R., Wakimoto B. Cytogenetic analysis of chromosome 3 in Drosophila melanogaster: the homeotic gene complex in polytene chromosome interval 84A-B. Genetics 1980, 94:115-133.
    • (1980) Genetics , vol.94 , pp. 115-133
    • Kaufman, T.C.1    Lewis, R.2    Wakimoto, B.3
  • 91
    • 0242552528 scopus 로고    scopus 로고
    • Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2
    • Kim D.W., Lassar A.B. Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2. Mol. Cell Biol. 2003, 23:8704-8717.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 8704-8717
    • Kim, D.W.1    Lassar, A.B.2
  • 93
    • 0345898928 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors
    • Kim Y.H., Choi C.Y., Lee S.-J., Conti M.A., Kim Y. Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. J. Biol. Chem. 1998, 273:25875-25879.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25875-25879
    • Kim, Y.H.1    Choi, C.Y.2    Lee, S.-J.3    Conti, M.A.4    Kim, Y.5
  • 95
    • 0038444550 scopus 로고    scopus 로고
    • Gata factor Pannier is required to establish competence for heart progenitor formation
    • Klinedinst S.L., Bodmer R. Gata factor Pannier is required to establish competence for heart progenitor formation. Development 2003, 130:3027-3038.
    • (2003) Development , vol.130 , pp. 3027-3038
    • Klinedinst, S.L.1    Bodmer, R.2
  • 96
    • 0027299922 scopus 로고
    • DNA-binding specificities of the GATA transcription factor family
    • Ko L.J., Engel J.D. DNA-binding specificities of the GATA transcription factor family. Mol. Cell Biol. 1993, 13:4011-4022.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 4011-4022
    • Ko, L.J.1    Engel, J.D.2
  • 98
    • 0027184211 scopus 로고
    • Csx: A murine homeobox-containing gene specifically expressed in the developing heart
    • Komuro I., Izumo S. Csx: A murine homeobox-containing gene specifically expressed in the developing heart. Proc. Natl. Acad. Sci. USA 1993, 90:8145-8149.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8145-8149
    • Komuro, I.1    Izumo, S.2
  • 99
    • 33748144332 scopus 로고    scopus 로고
    • Familial congenital heart disease, progressive atrioventricular block and the cardiac homeobox transcription factor gene NKX2.5: identification of a novel mutation
    • Konig K., Will J.C., Berger F., Muller D., Benson D.W. Familial congenital heart disease, progressive atrioventricular block and the cardiac homeobox transcription factor gene NKX2.5: identification of a novel mutation. Clin. Res. Cardiol. 2006, 95:499-503.
    • (2006) Clin. Res. Cardiol. , vol.95 , pp. 499-503
    • Konig, K.1    Will, J.C.2    Berger, F.3    Muller, D.4    Benson, D.W.5
  • 101
    • 0032714962 scopus 로고    scopus 로고
    • Tinman regulates the transcription of the beta3 tubulin gene (betaTub60D) in the dorsal vessel of Drosophila
    • Kremser T., Gajewski K., Schulz R.A., Renkawitz-Pohl R. Tinman regulates the transcription of the beta3 tubulin gene (betaTub60D) in the dorsal vessel of Drosophila. Dev. Biol. 1999, 216:327-339.
    • (1999) Dev. Biol. , vol.216 , pp. 327-339
    • Kremser, T.1    Gajewski, K.2    Schulz, R.A.3    Renkawitz-Pohl, R.4
  • 102
    • 0032749982 scopus 로고    scopus 로고
    • Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis
    • Kuo H., Chen J., Ruiz-Lozano P., Zou Y., Nemer M., Chien K.R. Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis. Development 1999, 126:4223-4234.
    • (1999) Development , vol.126 , pp. 4223-4234
    • Kuo, H.1    Chen, J.2    Ruiz-Lozano, P.3    Zou, Y.4    Nemer, M.5    Chien, K.R.6
  • 103
    • 0033524661 scopus 로고    scopus 로고
    • Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system
    • Kupershmidt S., Yang T., Anderson M.E., Wessels A., Niswender K.D., Magnuson M.A., Roden D.M. Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system. Circ. Res. 1999, 84:146-152.
    • (1999) Circ. Res. , vol.84 , pp. 146-152
    • Kupershmidt, S.1    Yang, T.2    Anderson, M.E.3    Wessels, A.4    Niswender, K.D.5    Magnuson, M.A.6    Roden, D.M.7
  • 104
    • 0032110463 scopus 로고    scopus 로고
    • Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2
    • Labbe E., Silvestri C., Hoodless P.A., Wrana J.L., Attisano L. Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2. Mol. Cell. 1998, 2:109-120.
    • (1998) Mol. Cell. , vol.2 , pp. 109-120
    • Labbe, E.1    Silvestri, C.2    Hoodless, P.A.3    Wrana, J.L.4    Attisano, L.5
  • 105
    • 0030589617 scopus 로고    scopus 로고
    • A new tinman-related gene, nxk2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm
    • Lee K.H., Breitbart R.E. A new tinman-related gene, nxk2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm. Dev. Biol. 1996, 180:722-731.
    • (1996) Dev. Biol. , vol.180 , pp. 722-731
    • Lee, K.H.1    Breitbart, R.E.2
  • 106
    • 0031844382 scopus 로고    scopus 로고
    • The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates Atrial Natriuretic Factor gene expression
    • Lee Y., Shioi T., Kasahara H., Jobe S.M., Wiese R.J., Markham B.E., Izumo S. The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates Atrial Natriuretic Factor gene expression. Mol. Cell Biol. 1998, 18:3120-3129.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 3120-3129
    • Lee, Y.1    Shioi, T.2    Kasahara, H.3    Jobe, S.M.4    Wiese, R.J.5    Markham, B.E.6    Izumo, S.7
  • 107
    • 0034640295 scopus 로고    scopus 로고
    • Jumonji, a nuclear protein that is necessary for normal heart development
    • Lee Y., Song A.J., Baker R., Micales B., Conway S.J., Lyons G.E. Jumonji, a nuclear protein that is necessary for normal heart development. Circ. Res. 2000, 86:932-938.
    • (2000) Circ. Res. , vol.86 , pp. 932-938
    • Lee, Y.1    Song, A.J.2    Baker, R.3    Micales, B.4    Conway, S.J.5    Lyons, G.E.6
  • 109
    • 34250205260 scopus 로고    scopus 로고
    • Carboxyl terminus of Nkx2.5 impairs its interaction with p300
    • Li T., Li Y.M., Jia Z.Q., Chen P., Ma K.T., Zhou C.Y. Carboxyl terminus of Nkx2.5 impairs its interaction with p300. J. Mol. Biol. 2007, 370:976-992.
    • (2007) J. Mol. Biol. , vol.370 , pp. 976-992
    • Li, T.1    Li, Y.M.2    Jia, Z.Q.3    Chen, P.4    Ma, K.T.5    Zhou, C.Y.6
  • 110
    • 0037091085 scopus 로고    scopus 로고
    • Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region
    • Liberatore C.M., Searcy-Schrick R.D., Vincent E.B., Yutzey K.E. Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region. Dev Biol. 2002, 244:243-256.
    • (2002) Dev Biol. , vol.244 , pp. 243-256
    • Liberatore, C.M.1    Searcy-Schrick, R.D.2    Vincent, E.B.3    Yutzey, K.E.4
  • 111
    • 0032937224 scopus 로고    scopus 로고
    • Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer
    • Lien C.L., Wu C., Mercer B., Webb R., Richardson J.A., Olson E.N. Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development 1999, 126:75-84.
    • (1999) Development , vol.126 , pp. 75-84
    • Lien, C.L.1    Wu, C.2    Mercer, B.3    Webb, R.4    Richardson, J.A.5    Olson, E.N.6
  • 112
    • 0037090906 scopus 로고    scopus 로고
    • Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site
    • Lien C.L., McAnally J., Richardson J.A., Olson E.N. Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site. Dev. Biol. 2002, 244:257-266.
    • (2002) Dev. Biol. , vol.244 , pp. 257-266
    • Lien, C.L.1    McAnally, J.2    Richardson, J.A.3    Olson, E.N.4
  • 113
    • 38149090853 scopus 로고    scopus 로고
    • Induction of Id2 expression by cardiac transcription factors GATA4 and Nkx2.5
    • Lim J.Y., Kim W.H., Kim J., Park S.I. Induction of Id2 expression by cardiac transcription factors GATA4 and Nkx2.5. J. Cell Biochem. 2007, 103:182-194.
    • (2007) J. Cell Biochem. , vol.103 , pp. 182-194
    • Lim, J.Y.1    Kim, W.H.2    Kim, J.3    Park, S.I.4
  • 116
    • 0027383023 scopus 로고
    • Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
    • Lints T.J., Parsons L.M., Hartley L., Lyons I., Harvey R.P. Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 1993, 119:419-431.
    • (1993) Development , vol.119 , pp. 419-431
    • Lints, T.J.1    Parsons, L.M.2    Hartley, L.3    Lyons, I.4    Harvey, R.P.5
  • 117
    • 33750631220 scopus 로고    scopus 로고
    • Coactivator control of cardiovascular growth and remodeling
    • Liu N., Olson E.N. Coactivator control of cardiovascular growth and remodeling. Curr. Opin. Cell Biol. 2006, 18:715-722.
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 715-722
    • Liu, N.1    Olson, E.N.2
  • 118
    • 0034967570 scopus 로고    scopus 로고
    • A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila
    • Lo P.C., Frasch M. A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila. Mech. Dev. 2001, 104:49-60.
    • (2001) Mech. Dev. , vol.104 , pp. 49-60
    • Lo, P.C.1    Frasch, M.2
  • 119
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2-5
    • Lyons I., Parsons L.M., Hartley L., Li R., Andrews J.E., Robb L., Harvey R.P. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2-5. Genes Dev. 1995, 9:1654-1666.
    • (1995) Genes Dev. , vol.9 , pp. 1654-1666
    • Lyons, I.1    Parsons, L.M.2    Hartley, L.3    Li, R.4    Andrews, J.E.5    Robb, L.6    Harvey, R.P.7
  • 123
    • 0029740603 scopus 로고    scopus 로고
    • BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.1
    • Mead P.E., Brivanlou I.H., Kelley C.M., Zon L.I. BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.1. Nature 1996, 382:357-360.
    • (1996) Nature , vol.382 , pp. 357-360
    • Mead, P.E.1    Brivanlou, I.H.2    Kelley, C.M.3    Zon, L.I.4
  • 124
    • 0027231112 scopus 로고
    • DNA-binding specificity of GATA family transcription factors
    • Merika M., Orkin S.H. DNA-binding specificity of GATA family transcription factors. Mol. Cell Biol. 1993, 13:3999-4010.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 3999-4010
    • Merika, M.1    Orkin, S.H.2
  • 126
    • 33847321958 scopus 로고    scopus 로고
    • Development of the cardiac conduction system
    • Mikawa T., Hurtado R. Development of the cardiac conduction system. Semin. Cell Dev. Biol. 2007, 18:90-100.
    • (2007) Semin. Cell Dev. Biol. , vol.18 , pp. 90-100
    • Mikawa, T.1    Hurtado, R.2
  • 127
    • 12944309290 scopus 로고    scopus 로고
    • The Drosophila melanogaster T-box genes midline and H15 are conserved regulators of heart development
    • Miskolczi-Mccallum C.M., Scavetta R.J., Svendsen P.C., Soanes K.H., Brook W.J. The Drosophila melanogaster T-box genes midline and H15 are conserved regulators of heart development. Dev. Biol. 2005, 278:459-472.
    • (2005) Dev. Biol. , vol.278 , pp. 459-472
    • Miskolczi-Mccallum, C.M.1    Scavetta, R.J.2    Svendsen, P.C.3    Soanes, K.H.4    Brook, W.J.5
  • 128
    • 0034671733 scopus 로고    scopus 로고
    • The zinc finger-containing transcription factors GATA-4,-5 and -6
    • Molkentin J.D. The zinc finger-containing transcription factors GATA-4,-5 and -6. J. Biol. Chem. 2000, 275:38949-38952.
    • (2000) J. Biol. Chem. , vol.275 , pp. 38949-38952
    • Molkentin, J.D.1
  • 134
    • 0035937415 scopus 로고    scopus 로고
    • Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube
    • Muhr J., Andersson E., Persson M., Jessell T.M., Ericson J. Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube. Cell 2001, 104:861-873.
    • (2001) Cell , vol.104 , pp. 861-873
    • Muhr, J.1    Andersson, E.2    Persson, M.3    Jessell, T.M.4    Ericson, J.5
  • 135
    • 0031835362 scopus 로고    scopus 로고
    • Tinman-related genes expressed during heart development in Xenopus
    • Newman C.S., Krieg P.A. Tinman-related genes expressed during heart development in Xenopus. Dev. Genet. 1998, 22:230-238.
    • (1998) Dev. Genet. , vol.22 , pp. 230-238
    • Newman, C.S.1    Krieg, P.A.2
  • 136
  • 139
    • 33847261472 scopus 로고    scopus 로고
    • Re-employment of developmental transcription factors in adult heart disease
    • Oka T., Xu J., Molkentin J.D. Re-employment of developmental transcription factors in adult heart disease. Semin. Cell Dev. Biol. 2007, 18:117-131.
    • (2007) Semin. Cell Dev. Biol. , vol.18 , pp. 117-131
    • Oka, T.1    Xu, J.2    Molkentin, J.D.3
  • 140
    • 0031812546 scopus 로고    scopus 로고
    • Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm
    • Onichtchouk D., Glinka A., Niehrs C. Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm. Development 1998, 125:1447-1456.
    • (1998) Development , vol.125 , pp. 1447-1456
    • Onichtchouk, D.1    Glinka, A.2    Niehrs, C.3
  • 142
    • 0030578428 scopus 로고    scopus 로고
    • The wingless pathway is directly involved in Drosophila heart development
    • Park M., Wu X., Golden K., Axelrod J.D., Bodmer R. The wingless pathway is directly involved in Drosophila heart development. Dev. Biol. 1996, 177:104-116.
    • (1996) Dev. Biol. , vol.177 , pp. 104-116
    • Park, M.1    Wu, X.2    Golden, K.3    Axelrod, J.D.4    Bodmer, R.5
  • 143
    • 0028170530 scopus 로고
    • Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
    • Paroush Z., Finley R.L., Kidd T., Wainwright S.M., Ingham P.W., Brent R., Ish-Horowicz D. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell 1994, 79:805-815.
    • (1994) Cell , vol.79 , pp. 805-815
    • Paroush, Z.1    Finley, R.L.2    Kidd, T.3    Wainwright, S.M.4    Ingham, P.W.5    Brent, R.6    Ish-Horowicz, D.7
  • 145
    • 0033602242 scopus 로고    scopus 로고
    • Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex
    • Passner J.M., Ryoo H.D., Shen L., Mann R.S., Aggarwal A.K. Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature 1999, 397:714-719.
    • (1999) Nature , vol.397 , pp. 714-719
    • Passner, J.M.1    Ryoo, H.D.2    Shen, L.3    Mann, R.S.4    Aggarwal, A.K.5
  • 146
    • 0033582545 scopus 로고    scopus 로고
    • Structure of a HoxB1-Pbx1 heterodimer bound to DNA: Role of the hexapeptide and a fourth homeodomain helix in complex formation
    • Piper D.E., Batchelor A.H., Chang C.-P., Cleary M.L., Wolberger C. Structure of a HoxB1-Pbx1 heterodimer bound to DNA: Role of the hexapeptide and a fourth homeodomain helix in complex formation. Cell 1999, 96:587-597.
    • (1999) Cell , vol.96 , pp. 587-597
    • Piper, D.E.1    Batchelor, A.H.2    Chang, C.-P.3    Cleary, M.L.4    Wolberger, C.5
  • 149
    • 14544291982 scopus 로고    scopus 로고
    • Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart
    • Qian L., Liu J., Bodmer R. Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart. Dev. Biol. 2005, 279:509-524.
    • (2005) Dev. Biol. , vol.279 , pp. 509-524
    • Qian, L.1    Liu, J.2    Bodmer, R.3
  • 152
    • 0031571635 scopus 로고    scopus 로고
    • Chicken Nkx-2.8: A novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm
    • Reecy J.M., Yamada M., Cummings K., Sosic D., Chen C.Y., Eichele G., Olson E.N., Schwartz R.J. Chicken Nkx-2.8: A novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm. Dev. Biol. 1997, 188:295-311.
    • (1997) Dev. Biol. , vol.188 , pp. 295-311
    • Reecy, J.M.1    Yamada, M.2    Cummings, K.3    Sosic, D.4    Chen, C.Y.5    Eichele, G.6    Olson, E.N.7    Schwartz, R.J.8
  • 153
    • 28844432418 scopus 로고    scopus 로고
    • The Dorsocross T-box genes are key components of the regulatory network controlling early cardiogenesis in Drosophila
    • Reim I., Frasch M. The Dorsocross T-box genes are key components of the regulatory network controlling early cardiogenesis in Drosophila. Development 2005, 132:4911-4925.
    • (2005) Development , vol.132 , pp. 4911-4925
    • Reim, I.1    Frasch, M.2
  • 154
    • 23144464213 scopus 로고    scopus 로고
    • Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila
    • Reim I., Mohler J.P., Frasch M. Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila. Mech. Dev. 2005, 122:1056-1069.
    • (2005) Mech. Dev. , vol.122 , pp. 1056-1069
    • Reim, I.1    Mohler, J.P.2    Frasch, M.3
  • 155
    • 0031882249 scopus 로고    scopus 로고
    • The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis
    • Riley P., Anson-Cartwright L., Cross J.C. The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis. Nat. Genet. 1998, 18:271-275.
    • (1998) Nat. Genet. , vol.18 , pp. 271-275
    • Riley, P.1    Anson-Cartwright, L.2    Cross, J.C.3
  • 156
    • 33845909812 scopus 로고    scopus 로고
    • Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart
    • Risebro C.A., Smart N., Dupays L., Breckenridge R., Mohun T.J., Riley P.R. Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart. Development 2006, 133:4595-4606.
    • (2006) Development , vol.133 , pp. 4595-4606
    • Risebro, C.A.1    Smart, N.2    Dupays, L.3    Breckenridge, R.4    Mohun, T.J.5    Riley, P.R.6
  • 157
    • 0000826497 scopus 로고
    • The circulation system and associated cells and tissues
    • Academic Press, New York, NY, M. Ashburner, T.R.F. Wright (Eds.)
    • Rizki T.M. The circulation system and associated cells and tissues. The Genetics and Biology of Drosophila 1978, Vol. 26:397-452. Academic Press, New York, NY. M. Ashburner, T.R.F. Wright (Eds.).
    • (1978) The Genetics and Biology of Drosophila , vol.26 , pp. 397-452
    • Rizki, T.M.1
  • 159
    • 0042347689 scopus 로고    scopus 로고
    • Id proteins in development, cell cycle and cancer
    • Ruzinova M.B., Benezra R. Id proteins in development, cell cycle and cancer. Trends Cell. Biol. 2003, 13:410-418.
    • (2003) Trends Cell. Biol. , vol.13 , pp. 410-418
    • Ruzinova, M.B.1    Benezra, R.2
  • 160
    • 33846849311 scopus 로고    scopus 로고
    • The NK homeodomain transcription factor Tinman is a direct activator of seven-up in the Drosophila dorsal vessel
    • Ryan K.M., Hendren J.D., Helander L.A., Cripps R.M. The NK homeodomain transcription factor Tinman is a direct activator of seven-up in the Drosophila dorsal vessel. Dev. Biol. 2007, 302:694-702.
    • (2007) Dev. Biol. , vol.302 , pp. 694-702
    • Ryan, K.M.1    Hendren, J.D.2    Helander, L.A.3    Cripps, R.M.4
  • 161
    • 0032809986 scopus 로고    scopus 로고
    • Expression of immediate early genes, GATA-4, and Nkx-2.5 in adrenergic-induced cardiac hypertrophy and during regression in adult mice
    • Saadane N., Alpert L., Chalifour L.E. Expression of immediate early genes, GATA-4, and Nkx-2.5 in adrenergic-induced cardiac hypertrophy and during regression in adult mice. Br. J. Pharmacol. 1999, 127:1165-1176.
    • (1999) Br. J. Pharmacol. , vol.127 , pp. 1165-1176
    • Saadane, N.1    Alpert, L.2    Chalifour, L.E.3
  • 162
    • 33847271755 scopus 로고    scopus 로고
    • A core transcriptional network for early mesoderm development in Drosophila melanogaster
    • Sandmann T., Girardot C., Brehme M., Tongprasit W., Stolc V., Furlong E.E. A core transcriptional network for early mesoderm development in Drosophila melanogaster. Genes Dev. 2007, 21:436-449.
    • (2007) Genes Dev. , vol.21 , pp. 436-449
    • Sandmann, T.1    Girardot, C.2    Brehme, M.3    Tongprasit, W.4    Stolc, V.5    Furlong, E.E.6
  • 164
    • 0034004871 scopus 로고    scopus 로고
    • BMP2 is required for early heart development during a distinct time period
    • Schlange T., Andree B., Arnold H.H., Brand T. BMP2 is required for early heart development during a distinct time period. Mech. Dev. 2000, 91:259-270.
    • (2000) Mech. Dev. , vol.91 , pp. 259-270
    • Schlange, T.1    Andree, B.2    Arnold, H.H.3    Brand, T.4
  • 165
    • 0023128247 scopus 로고
    • Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia
    • Schneuwly S., Klemenz R., Gehring W.J. Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia. Nature 1987, 325:816-818.
    • (1987) Nature , vol.325 , pp. 816-818
    • Schneuwly, S.1    Klemenz, R.2    Gehring, W.J.3
  • 167
    • 0029583152 scopus 로고
    • Induction of avian cardiac myogenesis by anterior endoderm
    • Schultheiss T.M., Xydas S., Lassar A.B. Induction of avian cardiac myogenesis by anterior endoderm. Development 1995, 121:4203-4214.
    • (1995) Development , vol.121 , pp. 4203-4214
    • Schultheiss, T.M.1    Xydas, S.2    Lassar, A.B.3
  • 168
    • 0031018002 scopus 로고    scopus 로고
    • A role for bone morphogenetic proteins in the induction of cardiac myogenesis
    • Schultheiss T.M., Burch J.B., Lassar A.B. A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev. 1997, 11:451-462.
    • (1997) Genes Dev. , vol.11 , pp. 451-462
    • Schultheiss, T.M.1    Burch, J.B.2    Lassar, A.B.3
  • 169
    • 0032727374 scopus 로고    scopus 로고
    • Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription
    • Schwartz R.J., Olson E.N. Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription. Development 1999, 126:4187-4192.
    • (1999) Development , vol.126 , pp. 4187-4192
    • Schwartz, R.J.1    Olson, E.N.2
  • 171
    • 0031647382 scopus 로고    scopus 로고
    • A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice
    • Searcy R.D., Vincent E.B., Liberatore C.M., Yutzey K.E. A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice. Development 1998, 125:4461-4470.
    • (1998) Development , vol.125 , pp. 4461-4470
    • Searcy, R.D.1    Vincent, E.B.2    Liberatore, C.M.3    Yutzey, K.E.4
  • 172
    • 0031815073 scopus 로고    scopus 로고
    • GATA-4 and Nkx2-5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression
    • Sepulveda J.L., Belaguli N., Nigam V., Chen C.-Y., Nemer M., Schwartz R.J. GATA-4 and Nkx2-5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol. Cell Biol. 1998, 18:3405-3415.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 3405-3415
    • Sepulveda, J.L.1    Belaguli, N.2    Nigam, V.3    Chen, C.-Y.4    Nemer, M.5    Schwartz, R.J.6
  • 173
    • 0037067697 scopus 로고    scopus 로고
    • Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity
    • Sepulveda J.L., Vlahopoulos S., Iyer D., Belaguli N., Schwartz R.J. Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity. J. Biol. Chem. 2002, 277:25775-25782.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25775-25782
    • Sepulveda, J.L.1    Vlahopoulos, S.2    Iyer, D.3    Belaguli, N.4    Schwartz, R.J.5
  • 175
    • 0346056964 scopus 로고    scopus 로고
    • Molecular regulation of cardiac chamber-specific gene expression
    • Small E.M., Krieg P.A. Molecular regulation of cardiac chamber-specific gene expression. Trends Cardiovasc. Med. 2004, 14:13-18.
    • (2004) Trends Cardiovasc. Med. , vol.14 , pp. 13-18
    • Small, E.M.1    Krieg, P.A.2
  • 176
    • 0029846335 scopus 로고    scopus 로고
    • A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, med-iates active transcriptional repression in vivo
    • Smith S.T., Jaynes J.B. A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, med-iates active transcriptional repression in vivo. Development 1996, 122:3141-3150.
    • (1996) Development , vol.122 , pp. 3141-3150
    • Smith, S.T.1    Jaynes, J.B.2
  • 179
    • 0030903857 scopus 로고    scopus 로고
    • Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
    • Srivastava D., Thomas T., Lin Q., Brown D., Olson E.N. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat. Genet. 1997, 16:154-160.
    • (1997) Nat. Genet. , vol.16 , pp. 154-160
    • Srivastava, D.1    Thomas, T.2    Lin, Q.3    Brown, D.4    Olson, E.N.5
  • 180
    • 0036362978 scopus 로고    scopus 로고
    • Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5
    • Stanley E.G., Biben C., Elefanty A., Barnett L., Koentgen F., Robb L., Harvey R.P. Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5. Int. J. Dev. Biol. 2002, 46:431-439.
    • (2002) Int. J. Dev. Biol. , vol.46 , pp. 431-439
    • Stanley, E.G.1    Biben, C.2    Elefanty, A.3    Barnett, L.4    Koentgen, F.5    Robb, L.6    Harvey, R.P.7
  • 182
    • 42449149191 scopus 로고    scopus 로고
    • Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression
    • Sultana N., Nag K., Hoshijima K., Laird D.W., Kawakami A., Hirose S. Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression. Proc. Natl. Acad. Sci. USA 2008, 105:4763-4768.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 4763-4768
    • Sultana, N.1    Nag, K.2    Hoshijima, K.3    Laird, D.W.4    Kawakami, A.5    Hirose, S.6
  • 183
    • 33748291758 scopus 로고    scopus 로고
    • Roles of jumonji and jumonji family genes in chromatin regulation and development
    • Takeuchi T., Watanabe Y., Takano-Shimizu T., Kondo S. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev. Dyn. 2006, 235:2449-2459.
    • (2006) Dev. Dyn. , vol.235 , pp. 2449-2459
    • Takeuchi, T.1    Watanabe, Y.2    Takano-Shimizu, T.3    Kondo, S.4
  • 185
    • 0032907924 scopus 로고    scopus 로고
    • The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development
    • Tanaka M., Chen Z., Bartunkova S., Yamasaki N., Izumo S. The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development 1999, 126:1269-1280.
    • (1999) Development , vol.126 , pp. 1269-1280
    • Tanaka, M.1    Chen, Z.2    Bartunkova, S.3    Yamasaki, N.4    Izumo, S.5
  • 186
    • 0344428124 scopus 로고    scopus 로고
    • Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5
    • Tanaka M., Wechsler S.B., Lee I.W., Yamasaki N., Lawitts J.A., Izumo S. Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5. Development 1999, 126:1439-1450.
    • (1999) Development , vol.126 , pp. 1439-1450
    • Tanaka, M.1    Wechsler, S.B.2    Lee, I.W.3    Yamasaki, N.4    Lawitts, J.A.5    Izumo, S.6
  • 187
    • 0034115494 scopus 로고    scopus 로고
    • Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting
    • Tanaka M., Yamasaki N., Izumo S. Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting. Mol. Cell Biol. 2000, 20:2874-2879.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 2874-2879
    • Tanaka, M.1    Yamasaki, N.2    Izumo, S.3
  • 189
    • 53249113134 scopus 로고    scopus 로고
    • Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number
    • Targoff K.L., Schell T., Yelon D. Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number. Dev. Biol. 2008, 322:314-321.
    • (2008) Dev. Biol. , vol.322 , pp. 314-321
    • Targoff, K.L.1    Schell, T.2    Yelon, D.3
  • 190
    • 0032874241 scopus 로고    scopus 로고
    • Comparative stability analysis of the thyroid transcription factor 1 and Antennapedia homeodomains: evidence for residue 54 in controlling the structural stability of the recognition helix
    • Tell G., Acquaviva R., Formisano S., Fogolari F., Pucillo C., Damante G. Comparative stability analysis of the thyroid transcription factor 1 and Antennapedia homeodomains: evidence for residue 54 in controlling the structural stability of the recognition helix. Int. J. Biochem. Cell Biol. 1999, 31:1339-1353.
    • (1999) Int. J. Biochem. Cell Biol. , vol.31 , pp. 1339-1353
    • Tell, G.1    Acquaviva, R.2    Formisano, S.3    Fogolari, F.4    Pucillo, C.5    Damante, G.6
  • 192
    • 0031861927 scopus 로고    scopus 로고
    • Upregulation of the cardiac homeobox gene Nkx2-5 (CSX) in feline right ventricular pressure overload
    • Thompson J.T., Rackley M.S., O'Brien T.X. Upregulation of the cardiac homeobox gene Nkx2-5 (CSX) in feline right ventricular pressure overload. Am. J. Physiol. 1998, 274:H1569-H1573.
    • (1998) Am. J. Physiol. , vol.274
    • Thompson, J.T.1    Rackley, M.S.2    O'Brien, T.X.3
  • 193
    • 0031895523 scopus 로고    scopus 로고
    • Two distinct types of repression domain in Engrailed: One interacts with the Groucho corepressor and is preferentially active on integrated target genes
    • Tolkunova E.N., Fujioka M., Kobayashi M., Deepali D., Jaynes J.B. Two distinct types of repression domain in Engrailed: One interacts with the Groucho corepressor and is preferentially active on integrated target genes. Mol. Cell Biol. 1998, 18:2804-2814.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 2804-2814
    • Tolkunova, E.N.1    Fujioka, M.2    Kobayashi, M.3    Deepali, D.4    Jaynes, J.B.5
  • 194
    • 0028294694 scopus 로고
    • XNkx2.5, a Xenopus gene related to Nkx-2.5 and tinman: Evidence for a conserved role in cardiac development
    • Tonissen K.F., Drysdale T.A., Lints T.J., Harvey R.P., Krieg P.A. XNkx2.5, a Xenopus gene related to Nkx-2.5 and tinman: Evidence for a conserved role in cardiac development. Dev. Biol. 1994, 162:325-328.
    • (1994) Dev. Biol. , vol.162 , pp. 325-328
    • Tonissen, K.F.1    Drysdale, T.A.2    Lints, T.J.3    Harvey, R.P.4    Krieg, P.A.5
  • 195
    • 0028658407 scopus 로고
    • Elongation of helix III of the NK-2 homeodomain upon binding to DNA: a secondary structure study by NMR
    • Tsao D., Gruschus J., Wang L.-H., Nirenberg M., Ferretti J. Elongation of helix III of the NK-2 homeodomain upon binding to DNA: a secondary structure study by NMR. Biochemistry 1994, 33:15053-15060.
    • (1994) Biochemistry , vol.33 , pp. 15053-15060
    • Tsao, D.1    Gruschus, J.2    Wang, L.-H.3    Nirenberg, M.4    Ferretti, J.5
  • 196
    • 33845229519 scopus 로고    scopus 로고
    • The Nk-2 box of the Drosophila homeodomain protein, Vnd, contributes to its repression activity in a Groucho-dependent manner
    • Uhler J., Zhang H., Syu L.J., Mellerick D.M. The Nk-2 box of the Drosophila homeodomain protein, Vnd, contributes to its repression activity in a Groucho-dependent manner. Mech. Dev. 2007, 124:1-10.
    • (2007) Mech. Dev. , vol.124 , pp. 1-10
    • Uhler, J.1    Zhang, H.2    Syu, L.J.3    Mellerick, D.M.4
  • 199
    • 4544315655 scopus 로고    scopus 로고
    • Protein kinases C and D med-iate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
    • Vega R.B., Harrison B.C., Meadows E., Roberts C.R., Papst P.J., Olson E.N., McKinsey T.A. Protein kinases C and D med-iate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol. Cell Biol. 2004, 24:8374-8385.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 8374-8385
    • Vega, R.B.1    Harrison, B.C.2    Meadows, E.3    Roberts, C.R.4    Papst, P.J.5    Olson, E.N.6    McKinsey, T.A.7
  • 200
    • 0027724196 scopus 로고
    • Structural study of rat thyroid transcription factor 1 homeodomain (TTF-1 HD) by nuclear magnetic resonance
    • Viglino P., Fogolari F., Formisano S., Bortolotti N., Damante G., Di Lauro R., Esposito G. Structural study of rat thyroid transcription factor 1 homeodomain (TTF-1 HD) by nuclear magnetic resonance. FEBS. Lett. 1993, 336:397-402.
    • (1993) FEBS. Lett. , vol.336 , pp. 397-402
    • Viglino, P.1    Fogolari, F.2    Formisano, S.3    Bortolotti, N.4    Damante, G.5    Di Lauro, R.6    Esposito, G.7
  • 202
    • 53149119958 scopus 로고    scopus 로고
    • Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier
    • Wang J., Zhang H., Iyer D., Feng X.H., Schwartz R.J. Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier. J. Biol. Chem. 2008, 283:23235-23243.
    • (2008) J. Biol. Chem. , vol.283 , pp. 23235-23243
    • Wang, J.1    Zhang, H.2    Iyer, D.3    Feng, X.H.4    Schwartz, R.J.5
  • 203
    • 0034662863 scopus 로고    scopus 로고
    • Intramolecular control of transcriptional activity by the NK2-specific domain in NK-2 homeodomain proteins
    • Watada H., Mirmira R.G., Kalamaras J., German M.S. Intramolecular control of transcriptional activity by the NK2-specific domain in NK-2 homeodomain proteins. Proc. Natl. Acad. Sci. USA 2000, 97:9443-9448.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9443-9448
    • Watada, H.1    Mirmira, R.G.2    Kalamaras, J.3    German, M.S.4
  • 204
    • 0036848609 scopus 로고    scopus 로고
    • Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD
    • Watanabe Y., Benson D.W., Yano S., Akagi T., Yoshino M., Murray J.C. Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD. J. Med. Genet. 2002, 39:807-811.
    • (2002) J. Med. Genet. , vol.39 , pp. 807-811
    • Watanabe, Y.1    Benson, D.W.2    Yano, S.3    Akagi, T.4    Yoshino, M.5    Murray, J.C.6
  • 205
    • 0032414597 scopus 로고    scopus 로고
    • A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis
    • Weisberg E., Winnier G.E., Chen X., Farnsworth C.L., Hogan B.L., Whitman M. A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis. Mech. Dev. 1998, 79:17-27.
    • (1998) Mech. Dev. , vol.79 , pp. 17-27
    • Weisberg, E.1    Winnier, G.E.2    Chen, X.3    Farnsworth, C.L.4    Hogan, B.L.5    Whitman, M.6
  • 206
    • 33845442108 scopus 로고    scopus 로고
    • Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart
    • Wu S.M., Fujiwara Y., Cibulsky S.M., Clapham D.E., Lien C.L., Schultheiss T.M., Orkin S.H. Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 2006, 127:1137-1150.
    • (2006) Cell , vol.127 , pp. 1137-1150
    • Wu, S.M.1    Fujiwara, Y.2    Cibulsky, S.M.3    Clapham, D.E.4    Lien, C.L.5    Schultheiss, T.M.6    Orkin, S.H.7
  • 207
    • 0029000929 scopus 로고
    • Heart development in Drosophila requires the segment polarity gene wingless
    • Wu X., Golden K., Bodmer R. Heart development in Drosophila requires the segment polarity gene wingless. Dev. Biol. 1995, 169:619-628.
    • (1995) Dev. Biol. , vol.169 , pp. 619-628
    • Wu, X.1    Golden, K.2    Bodmer, R.3
  • 208
    • 0032145411 scopus 로고    scopus 로고
    • Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm
    • Xu X., Yin Z., Hudson J.B., Ferguson E.L., Frasch M. Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. Genes Dev. 1998, 12:2354-2370.
    • (1998) Genes Dev. , vol.12 , pp. 2354-2370
    • Xu, X.1    Yin, Z.2    Hudson, J.B.3    Ferguson, E.L.4    Frasch, M.5
  • 209
    • 0035891429 scopus 로고    scopus 로고
    • The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation
    • Yamagishi H., Yamagishi C., Nakagawa O., Harvey R.P., Olson E.N., Srivastava D. The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev. Biol. 2001, 239:190-203.
    • (2001) Dev. Biol. , vol.239 , pp. 190-203
    • Yamagishi, H.1    Yamagishi, C.2    Nakagawa, O.3    Harvey, R.P.4    Olson, E.N.5    Srivastava, D.6
  • 210
    • 0031468348 scopus 로고    scopus 로고
    • Regulation of twist target gene tinman by modular cis-regulatory elements during early mesoderm development
    • Yin Z., Xu X.L., Frasch M. Regulation of twist target gene tinman by modular cis-regulatory elements during early mesoderm development. Development 1997, 124:4971-4982.
    • (1997) Development , vol.124 , pp. 4971-4982
    • Yin, Z.1    Xu, X.L.2    Frasch, M.3
  • 211
    • 0031805714 scopus 로고    scopus 로고
    • Regulation and function of tinman during dorsal mesoderm induction and heart specification in Drosophila
    • Yin Z., Frasch M. Regulation and function of tinman during dorsal mesoderm induction and heart specification in Drosophila. Dev. Genet. 1998, 22:187-200.
    • (1998) Dev. Genet. , vol.22 , pp. 187-200
    • Yin, Z.1    Frasch, M.2
  • 212
    • 0037144658 scopus 로고    scopus 로고
    • Early signals in cardiac development
    • Zaffran S., Frasch M. Early signals in cardiac development. Circ. Res. 2002, 91:457-469.
    • (2002) Circ. Res. , vol.91 , pp. 457-469
    • Zaffran, S.1    Frasch, M.2
  • 213
    • 33751061126 scopus 로고    scopus 로고
    • Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila
    • Zaffran S., Reim I., Qian L., Lo P.C., Bodmer R., Frasch M. Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila. Development 2006, 133:4073-4083.
    • (2006) Development , vol.133 , pp. 4073-4083
    • Zaffran, S.1    Reim, I.2    Qian, L.3    Lo, P.C.4    Bodmer, R.5    Frasch, M.6
  • 214
    • 33847189172 scopus 로고    scopus 로고
    • Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo
    • Zeitlinger J., Zinzen R.P., Stark A., Kellis M., Zhang H., Young R.A., Levine M. Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo. Genes Dev. 2007, 21:385-390.
    • (2007) Genes Dev. , vol.21 , pp. 385-390
    • Zeitlinger, J.1    Zinzen, R.P.2    Stark, A.3    Kellis, M.4    Zhang, H.5    Young, R.A.6    Levine, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.