Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development

Development

Volumn 124, Issue 24, 1997, Pages 4971-4982

  Yin, Zhizhang ^a   Xu, Xiao Lei ^a   Frasch, Manfred ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Drosophila; Mesoderm; Patterning; Tinman

Indexed keywords

CIS ACTING ELEMENT; HELIX LOOP HELIX PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; ENHANCER REGION; GENE EXPRESSION REGULATION; HOMEOBOX; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING;

ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; BODY PATTERNING; CLONING, MOLECULAR; CONSERVED SEQUENCE; DNA; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENHANCER ELEMENTS (GENETICS); GATA TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; MESODERM; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TWIST TRANSCRIPTION FACTOR;

EID: 0031468348     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Austin, R. and Biggin, M. (1995). A domain of the even-skipped protein represses transcription by preventing TFIID binding to a promoter: repression by cooperative blocking. Mol. Cell. Biol. 15, 4683-4693.
2. Azpiazu, N. and Frasch, M. (1993). tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 7, 1325-1340.
3. Azpiazu, N., Lawrence, P., Vincent, J.-P. and Frasch, M. (1996). Segmentation and specification of the Drosophila mesoderm. Genes Dev. 10, 3183-3194
4. Baehrecke, E. (1997). who encodes a KH RNA binding protein that functions in muscle development. Development 124, 1323-1332.
5. Baylies, M. K. and Bate, M. (1996). twist: A myogenic switch in Drosophila. Science 272, 1481-1484.
6. Berleth, T., Burri, M., Thoma, G., Bopp, D., Richstein, G., Frigerio, G., Noll, M. and Nusslein-Volhard, C. (1988). The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. EMBO J. 7, 1749-1756
7. Bodmer, R. (1993). The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118, 719-729.
8. Bodmer, R., Jan, L. Y. and Jan, Y. N. (1990). A new homeobox-containing gene, msh-2, is Iransiently expressed early during mesoderm formation of Drosophila. Development 110, 661-669.
9. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
10. Brand, T., Andree, B., Schneider, A., Buchberger, A. and Arnold, H. (1997) Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development. Mech. Dev. 64, 53-59.
11. Branner, E., Peter, O., Schweizer, L. and Basler, K. (1997). pangolin encodes a Lef-l homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature 385, 829-833.
12. Casal, J. and Leptin, M. (1996). Identification of novel genes in Drosophila reveals the complex regulation of early gene activity in the mesoderm. Proc. Natl. Acad. Sci. USA 93, 10327-10332
13. Cohen, S. and Jürgens, G. (1990). Mediation of Drosophila head development by gap-like segmentation genes. Nature 346, 482-485.
14. Cronmiller, C., Schedl, P. and Cline, T. W. (1988). Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development. Genes Dev. 2, 1666-1676.
15. Dalton, D., Chadwick, R. and McGinnis, W. (1989). Expression and embryonic function of empty spiracles: a Drosophila homeo-box gene with two patterning functions on the anterior-posterior axis of the embryo. Gen. Dev. 3, 1940-1956.
16. Evans, S., Yan, W., Murillo, M., Ponce, J. and Papalopulu, N. (1995). tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman. Development 121, 3889-3899.
17. Kinkelstein, R. and Perrimon, N. (1990). The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development. Nature 346, 485-488.
18. Frasch, M. (1995). Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. Nature 374, 464-467.
19. Frasch, M., Hoey, T., Kushlow, C., Doyle, H. J. and Levine, M. (1987) Characterization and localization of the even-skipped protein of Drosophila. EMBO J. 6, 749-759.
20. Frasch, M. and Levine, M. (1987). Complementary patterns af even-skipped and fushi taratu expression involve their differential regulation by a common set of segmentation genes in Drosophila. Genes Dev. 1, 981-995.
21. Gorczyka, M. G., Phyllis, R. W. and Budnik, V. (1994). The role of tinman, a mesodermal cell fate gene, in axon pathfinding during the development of the transverse nerve in Drosophila. Development 120, 2143-2152.
22. Goriely, A., Stella, M., Coffinier, C., Kessler, D., Mailhos, C., Dessain, S. and Desplan, C. (1996). A functional homologue of goosecoid in Drosophila. Development 122, 1641-1650.
23. Hahn, M. and Jackle, H. (1996). Drosophila goosecoid participates in neural development but not in body axis formation. EMBO J. 15, 3077-3084.
24. Han, K. and Manley, J. (1993). Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain. Genes Dev. 7, 491-503.
25. Hanna-Rose, W., Licht, J. and Hansen, U. (1997). Two evolutionarily conserved repression domains in the Drosophila Krüppel protein differ in activator specificity. Mol. Cell. Biol. 17, 4820-4829.
26. Harvey, R. (1996). NK-2 homeobox genes and heart development. Dev. Biol. 178, 203-216.
27. Heberlein, U., England, B. and Tjian, R. (1985) Characterization of Drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene. Cell 41, 965-977.
28. Hebrok, M., Füchtbauer, A. and Füchtbauer, E. (1997). Repression of muscle-specific gene activation by the murine Twist protein. Exp. Cell Res. 232, 295-303.
29. Hoey, T., Frasch, M. and Levine, M. (1988). Sequence-specific DNA binding activities of even-skipped and other homeobox proteins in Drosophila. Nature 332, 858-861.
30. Ip, T. Y., Park, R. E., Kosman, D., Yazdanbakhsh, K. and Levine, M. (1992a). dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo. Genes Dev. 6, 1518-1530.
31. Ip, Y. T., Park, R. E., Kosman, D., Bier, E. and Levine, M. (1992b). The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm ofthe Drosophila embryo Genes Dev. 6, 1728-1739.
32. Jagla, K., Frasch, M., Jagla, T., Dretzen, G., Bellard, F. and Bellard, M. (1997). ladybird, a new component of the cardiogenic pathway in Drosophila required for diversification of heart precursors. Development, in press
33. Kosman, D., Ip, Y. T., Levine, M. and Arora, K. (1991) Establishment of the mesoderm-neuroectoderm boundary in the Drosophila embryo. Science 252, 118-122.
34. Lai, Z., Fortini, M. and Rubin, G. (1991). The embryonic expression patterns of zfh-1 and zfh-2, two Drosophila genes encoding novel zinc-finger homeodomain proteins. Mech. Dev. 34, 123-134.
35. Lee, K., Xu, Q. and Breitbart, R. (1996). A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm. Dev. Biol. 180, 722-731.
36. Lee, Y., Park, T., Schulz, R. and Kim, Y. (1997). Twist-mediated activation of the NK-4 homeobox gene in the visceral mesoderm of Drosophila requires two distinct clusters of E-box regulatory elements. J. Biol. Chem. 272, 17531-17541.
37. Leptin, M. (1991). twist and snail as positive and negative regulators during Drosophila mesoderm formation. Genes Dev. 5, 1568-1576.
38. Lilly, B., Galewsky, S., Firulli, A., Schulz, R. and Olson, E. (1994). D-MEF2: a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. Proc. Natl. Acad. Sci. USA 91, 5662-5666.
39. Lints, T. J., Parsons, L. M., Hartley, L., Lyons, I. and Harvey, R. (1993) Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119, 419-431.
40. Lo, P. and Frasch, M. (1997) A novel KH domain protein mediates cell adhesion processes in Drosophila. Dev. Biol., in press.
41. Macdonald, P. M., Ingham, P. and Struhl, G. (1986). Isolation, structure, and expression of even-skipped: a second pair-rule gene of Drosophila containing a homeo box. Cell 47, 721-34.
42. McGinnis, W., Levine, M. S., Hafen, E., Kuroiwa, A. and Gehring, W. J. (1984). A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes. Nature 308, 428-33.
43. Merrill, V. K., Turner, F. R. and Kaufman, T. C. (1987). A genetic and developmental analysis of mutations in the Deformed locus in Drosophila melanogaster. Dev. Biol. 122, 379-95.
44. Murre, C., McCaw, P. S. and Baltimore, D. (1989a). A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56, 777-783.
45. Murre, C., McCaw, P. S., Vaessin, H., Caudy, M., Jan, L. Y., Jan, Y. N., Cabrera, C. V., Buskin, J. N., Hauschka, S. D., Lassar, A. B., Weintraub, H. and Baltimore, D. (1989b). Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 58, 537-544.
46. Nelson, R., Fessier, L., Takagi, Y., Blumberg, B., Keene, D., Olson, P., Parker, C. and Fessler, J. (1994). Peroxidasin: a novel enzyme-matrix protein of Drosophila development. EMBO J. 13, 3438-3447.
47. Nguyen, H., Bodmer, R., Abmayr, S., McDermott, J. and Spoerel, N. (1994). D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis. Proc. Natl. Acad. Sci. USA 91, 7520-7524.
48. Rehorri, K.-P., Thelen, H., Michelson, A. and Reuter, R. (1996). A molecular aspect of hemalopoiesis and endoderm development common to vertebrates and Drosophila. Development 122, 4023-4031.
49. Schultheiss, T., Burch, J. and Lassar, A. (1997) A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev. 11, 451-462.
50. Shishido, E., Higashijima, S., Emori, Y. and Saigo, K. (1993). Two FGF- receptor homologues of Drosophila: one is expressed in mesodermal primordium in early embryos. Development 117, 751-761.
51. Simpson, P. (1983). Maternal-zygotic gene interactions during formation of the dorsovemral pattern in Drosophila embryos. Genetics 105, 615-632.
52. Spicer, D., Rhee, J., Cheung, W. and Lassar, A. (1996). Inhibition of myogenic bHLH and MEF2 transcription factors by the bHLH protein Twist. Science 272, 1476-1480.
53. Sprenger, F., Stevens, L. M. and Nüsslein-Volhard, C. (1989). The Dmsophila gene torso encodes a putative receptor tyrosine kinase. Nature 338, 478-483.
54. Taylor, M., Beatty, K., Hunter, H. and Baylies, M. (1995). Drosophila MEF2 is regulated by twist and is expressed in both the primordia and differentiated cells of the embryonic somatic, visceral and heart musculature. Mech. Dev. 50, 29-41.
55. Technau, G. M. and Campos-Ortega, J. A. (1985). Fate-mapping in wildtype Drosophila melanogaster II. Injections of horseradish peroxidase in cells of the early gastrula stage. Roux's Arch. Dev. Biol. 194, 196-212.
56. Tepass, U., Fessier, L., Aziz, A. and Hartenstein, V. (1994). Embryonic origin of hemocytes and their relationship to cell death in Drosophila. Development 120, 1829-1837.
57. Thisse, B., Stoetzel, C., Gorostiza-Thisse, C. and Perrin-Schmitt, F. (1988). Sequence of the twist gene and nuclear localization of its protein in endomcsodermal cells of early Drosophila embryos. EMBO J. 7, 2175-2183.
58. Thummel, C. S., Boulet, A. M. and Lipshitz, H. D. (1988). Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. Gene 74, 445-450.
59. Tonissen, K., Drysdale, T., Lints, T., Harvey, R. and Krieg, P. (1994) XNkx-2.5, a Xenopus gene related to Nkv-2.5 and tinman: evidence for a conserved role in cardiac development. Dev. Biol. 162, 325-328.
60. Um, M., Li, C. and Manley, J. (1995). The transcriptional repressor even-skipped interacts directly with TATA-binding prolein. Mol. Cell. Biol. 15, 5007-5016.
61. van de Wetering, M., Cavallo, R., Dooijes, D., van Beest, M., van Es, J., Loureiro, J., Ypma, A., Hursh, D., Jones, T., Bejsovec, A., Peifer, M., Mortin, M. and Clevers, H. (1997). Armadillo reactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88, 789-799.
62. Wimmer, E., Jackle, H., Pfeifle, C. and Cohen, S. (1991). A Drosophila homologue of human Sp1 is a head-specific segmentation gene. Nature 366, 690-694.
63. Wu, X., Golden, K. and Bodmer, R. (1995). Heart development in Drosophila requires the segment polarity gene wingless. Dev. Biol. 169, 619-628.
64. Zaffran, S., Astier, M., Gratecos, D. and Semeriva, M. (1997). The held out wings (how) Drosophila gene encodes a putative RNA-binding protein involved in the control of muscular and cardiac activity. Development 124, 2087-2098.