Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

Developmental Cell

Volumn 5, Issue 6, 2003, Pages 877-889

  Cai, Chen Leng ^a   Liang, Xingqun ^a   Shi, Yunqing ^a   Chu, Po Hsien ^a   Pfaff, Samuel L ^b   Chen, Ju ^a   Evans, Sylvia ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; LIM PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; GENE EXPRESSION; GENE FUNCTION; HEART ATRIUM; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART RIGHT VENTRICLE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINEAGE; CELL MOVEMENT; CELL SURVIVAL; ENDODERM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HEART DEFECTS, CONGENITAL; HOMEODOMAIN PROTEINS; HOMOZYGOTE; MESODERM; MICE; MICE, KNOCKOUT; MYOCARDIUM; NERVE TISSUE PROTEINS; PHARYNX; PREGNANCY; STEM CELLS;

ANIMALIA; MAMMALIA;

EID: 0346783332     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(03)00363-0     Document Type: Article

References (46)

1. Abu-Issa R. Smyth G. Smoak I. Yamamura K. Meyers E.N. Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse Development 129 2002 4613-4625
2. Ahlgren U. Pfaff S.L. Jessell T.M. Edlund T. Edlund H. Independent requirement for ISL1 in formation of pancreatic mesenchyme and isl cells Nature 385 1997 257-260
3. Bruneau B.G. Logan M. Davis N. Levi T. Tabin C.J. Seidman J.G. Seidman C.E. Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome Dev. Biol. 211 1999 100-108
4. Campione M. Ros M.A. Icardo J.M. Piedra E. Christoffels V.M. Schweickert A. Blum M. Franco D. Moorman A.F. Pitx2 expression defines a left cardiac lineage of cells: evidence for atrial and ventricular molecular isomerism in the iv/iv mice Dev. Biol. 231 2001 252-264
5. Cross J.C. Flannery M.L. Blanar M.A. Steingrimsson E. Jenkins N.A. Copeland N.G. Rutter W.J. Werb Z. Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development Development 121 1995 2513-2523
6. Crossley P.H. Martin G.R. The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo Development 121 1995 439-451
7. Cserjesi P. Brown D. Lyons G.E. Olson E.N. Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development Dev. Biol. 170 1995 664-678
8. de la Cruz, M.V., and Sanchez-Gomez, C. (2000). Straight heart tube. Primitive cardiac cavities vs. primitive cardiac segments. In Living Morphogenesis of the Heart, M.V. de La Cruz and R.R. Markwald, eds. (Boston: Birkhauser), pp. 85-99
9. Dudley A.T. Robertson E.J. Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos Dev. Dyn. 208 1997 349-362
10. Feldman B. Poueymirou W. Papaioannou V.E. DeChiara T.M. Goldfarb M. Requirement of FGF-4 for postimplantation mouse development Science 267 1995 246-249
11. Franco D. Markman M.M. Wagenaar G.T. Ya J. Lamers W.H. Moorman A.F. Myosin light chain 2a and 2v identifies the embryonic outflow tract myocardium in the developing rodent heart Anat. Rec. 254 1999 135-146
12. Franco D. Campione M. Kelly R. Zammit P.S. Buckingham M. Lamers W.H. Moorman A.F. Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart Circ. Res. 87 2000 984-991
13. Frank D.U. Fotheringham L.K. Brewer J.A. Muglia L.J. Tristani-Firouzi M. Capecchi M.R. Moon A.M. An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome Development 129 2002 4591-4603
14. Harvey R.P. Biben C. Elliott D.A. Transcriptional control and pattern formation in the developing vertebrate heart: studies on Nk-2 class homeodomain factors In Heart Development Harvey R.P. Rosenthal N. eds. 1999 111-129 Academic Press San Diego, CA
15. Haun C. Alexander J. Stainier D.Y. Okkema P.G. Rescue of Caenorhabditis elegans pharyngeal development by a vertebrate heart specification gene Proc. Natl. Acad. Sci. USA 95 1998 5072-5075
16. Hoffman J.I. Kaplan S. The incidence of congenital heart disease J. Am. Coll. Cardiol. 39 2002 1890-1900
17. Kaufman M.H. The Atlas of Mouse Development 1999 Academic Press San Diego, CA
18. Kelly R.G. Buckingham M.E. The anterior heart-forming field: voyage to the arterial pole of the heart Trends Genet. 18 2002 210-216
19. Kelly R.G. Brown N.A. Buckingham M.E. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm Dev. Cell 1 2001 435-440
20. Kim R.Y. Robertson E.J. Solloway M.J. Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart Dev. Biol. 235 2001 449-466
21. Kirby M.L. Molecular embryogenesis of the heart Pediatr. Dev. Pathol. 5 2002 516-543
22. Kubalak S.W. Miller-Hance W.C. O'Brien T.X. Dyson E. Chien K.R. Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis J. Biol. Chem. 269 1994 16961-16970
23. Lamers W.H. Moorman A.F. Cardiac septation: a late contribution of the embryonic primary myocardium to heart morphogenesis Circ. Res. 91 2002 93-103
24. Lough J. Sugi Y. Endoderm and heart development Dev. Dyn. 217 2000 327-342
25. Lyons K.M. Hogan B.L. Robertson E.J. Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development Mech. Dev. 50 1995 71-83
26. Mjaatvedt C.H. Nakaoka T. Moreno-Rodriguez R. Norris R.A. Kern M.J. Eisenberg C.A. Turner D. Markwald R.R. The outflow tract of the heart is recruited from a novel heart-forming field Dev. Biol. 238 2001 97-109
27. Niswander L. Martin G.R. Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse Development 114 1992 755-768
28. O'Brien T.X. Lee K.J. Chien K.R. Positional specification of ventricular myosin light chain 2 expression in the primitive murine heart tube Proc. Natl. Acad. Sci. USA 90 1993 5157-5161
29. Park M. Lewis C. Turbay D. Chung A. Chen J.N. Evans S. Breitbart R.E. Fishman M.C. Izumo S. Bodmer R. Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes Proc. Natl. Acad. Sci. USA 95 1998 9366-9371
30. Pexieder T. Standardized method for study of normal and abnormal cardiac development in chick, rat, mouse, dog, and human embryos Teratology 33 1986 91C-92C
31. Pfaff S.L. Mendelsohn M. Stewart C.L. Edlund T. Jessell T.M. Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation Cell 84 1996 309-320
32. Ranganayakulu G. Elliott D.A. Harvey R.P. Olson E.N. Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice Development 125 1998 3037-3048
33. Sekine K. Ohuchi H. Fujiwara M. Yamasaki M. Yoshizawa T. Sato T. Yagishita N. Matsui D. Koga Y. Itoh N. Kato S. Fgf10 is essential for limb and lung formation Nat. Genet. 21 1999 138-141
34. Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain Nat. Genet. 21 1999 70-71
35. Srinivas S. Watanabe T. Lin C.S. William C.M. Tanabe Y. Jessell T.M. Costantini F. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus BMC Dev. Biol. 1 2001 4
36. Sun X. Meyers E.N. Lewandoski M. Martin G.R. Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo Genes Dev. 13 1999 1834-1846
37. Tanaka M. Chen Z. Bartunkova S. Yamasaki N. Izumo S. The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development Development 126 1999 1269-1280
38. Thomas T. Yamagishi H. Overbeek P.A. Olson E.N. Srivastava D. The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness Dev. Biol. 196 1998 228-236
39. Thor S. Thomas J.B. The Drosophila isl gene governs axon pathfinding and neurotransmitter identity Neuron 18 1997 397-409
40. Waldo K.L. Kumiski D.H. Wallis K.T. Stadt H.A. Hutson M.R. Platt D.H. Kirby M.L. Conotruncal myocardium arises from a secondary heart field Development 128 2001 3179-3188
41. Wilkinson, D.G. ed. (1992). In Situ Hybridization: A Practical Approach (New York: Oxford University Press).
42. Winnier G. Blessing M. Labosky P.A. Hogan B.L. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse Genes Dev. 9 1995 2105-2116
43. Yuan S. Schoenwolf G.C. Isl-1 marks the early heart rudiments and is asymmetrically expressed during early rotation of the foregut in the chick embryo Anat. Rec. 260 2000 204-207
44. Yutzey K.E. Kirby M.L. Wherefore heart thou? Embryonic origins of cardiogenic mesoderm Dev. Dyn. 223 2002 307-320
45. Zhang H. Bradley A. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development Development 122 1996 2977-2986
46. Zinyk D.L. Mercer E.H. Harris E. Anderson D.J. Joyner A.L. Fate mapping of the mouse midbrain-hindbrain constriction using a site-specific recombination system Curr. Biol. 8 1998 665-668