Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis

Development

Volumn 126, Issue 19, 1999, Pages 4223-4234

  Kuo, Hai Chien ^a   Chen, Ju ^a   Ruiz Lozano, Pilar ^a   Zou, Yimin ^a   Nemer, Mona ^c   Chien, Kenneth R ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE

Author keywords

Cardiac hypertrophy; Cardiogenesis; CARP; GATA 4; Heart segment specificity; Mouse; Nkx2.5; Transcriptional regulation

Indexed keywords

ANKYRIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DNA SEQUENCE; EMBRYO; GENE EXPRESSION REGULATION; HEART ATRIUM; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART VENTRICLE; HEART VENTRICLE HYPERTROPHY; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TRANSGENIC MOUSE;

AGE FACTORS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARDIOMEGALY; CELLS, CULTURED; DNA-BINDING PROTEINS; DOWN-REGULATION; EXONS; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REGULATOR; HEART; HOMEODOMAIN PROTEINS; MICE; MICE, TRANSGENIC; MODELS, GENETIC; MUSCLE PROTEINS; NUCLEAR PROTEINS; PLASMIDS; RATS; REPRESSOR PROTEINS; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; XENOPUS PROTEINS;

EID: 0032749982     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Arber, S., Hunter, J. J., Ross, J. J., Hongo, M., Sansig, G., Borg, J., Perriard, J. C., Chien, K. R. and Caroni, P. (1997). MLP-deficieni mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell 88, 393-403.
2. Baumeister, A., Arber, S. and Caroni, P. (1997). Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis. J. Cell Biol. 139, 1231-1242.
3. Chen, Y. C. and Schwartz, R. J. (1996). Recruitment of the tinman homolog Nkx2.5 by serum response factor activates cardiac alpha-actin gene transcription. Mol. Cell. Biol. 16, 6372-6384.
4. Durocher, D., Charron, F., Warren, R., Schwartz, R. J. and Nemer, M. (1997). The cardiac transcription factors Nkx2.5 and GATA-4 are mutual cofactors. EMBO J. 16, 5687-5696
5. Evans, S. M., Tai, L. J., Tan, V. P., Newton, C. B. and Chien, K. R. (1994). Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype. Mol. Cell. Biol. 14, 4269-4279.
6. Fishman, M. C. and Chien, K. R. (1997). Fashioning the vertebrate heart: earliest embryonic decisions. Development 124, 2099-2117.
7. Franco, D., Kelly, R., Lamers, W. H., Buckingham, M. and Moorman, A. F. (1997). Regionalized transcriptional domains of myosin light chain 3f transgenes in the embryonic mouse heart: morphogenetic implications. Dev. Biol. 188, 17-33.
8. He, C. Z. and Burch, J. B. (1997). The chicken GATA-6 locus contains multiple control regions that confer distinct patterns of heart region-specific expression in transgenic mouse embryos. J. Biol. Chem. 272, 28550-28556.
9. 1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc. Natl. Acad. Sci. USA, 94, 7543-7548.
10. Izumo, S., Lompre, A. M., Matsuoka, R., Koren, G., Schwartz, K., Nadal, G. B. and Mahdavi, V. (1987). Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals. J. Clin. Invest. 79, 970-977.
11. Jeyaseelan, R., Poizat, C., Baker, R. K., Abdishoo, S., Isterabadi, L. B., Lyons, G. E. and Kedes, L. (1997). A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes. J. Biol. Chem. 272, 22800-22808.
12. Kubalak, S. W., Miller, H. W., O'Brien, T. X., Dyson, E. and Chien, K. R. (1994). Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis. J. Biol. Chem. 269, 16961-16970.
13. Kuisk, I. R., Li, H., Tran, D. and Capetanaki, Y. (1996). A single MEF2 site governs desmin transcription in both heart and skeletal muscle during mouse embryogenesis. Dev. Biol. 174, 1-13.
14. Kuo, C. T., Morrisey, E. E., Anandappa, R., Sigrist, K., Lu, M. M., Parmacek, M. S., Soudais, C. and Leiden, J. M. (1997). GATA4 transcripotion factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 11, 1048-1060.
15. Lee, Y., Shioi, T., Kasahara, H., Jobe, S. M., Wiese, R., Markham, B. E., Izumo, S. (1998). The cardiac tissue-restricted Homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression. Mol. Cell. Biol. 18, 3120-3129.
16. Lee, R. T., Bloch, K. D., Pfeffer, J. M., Pfeffer, M. A., Neer, E. J. and Seidman, C. E. (1988). Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy. J. Clin. Invest. 81, 431-434.
17. Lyons, I., Parsons, L. M., Hartley, L., Li, R. andrews, J. E., Robb, L. and Harvey, R. P. (1995). Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2.5. Genes Dev. 9, 1654-1666.
18. Molkentin, J. D., Lin, Q., Duncan, S. A. and Olson, E. N. (1997) Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 11, 1061-1072.
19. Molkentin, J. D., Lu, J-R., Antos, C. L., Markham, B., Richardson, J., Robbins, J., Grant, S. R. and Olson E. N. (1998). A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93, 215-228.
20. O'Brien, T. X., Lee, K. J. and Chien, K. R. (1993). Positional specification of ventricular myosin light chain 2 expression in the primitive murine heart tube. Proc. Natl. Acad. Sci. USA 90, 5157-5161.
21. Olson, E. and Srivastava, D. (1996). Molecular pathways controlling heart development. Science 272, 671-676.
22. Reecy, J. M., Li, X., Yamada, M., DeMayo, F., Newman, C. S., Harvey R. P. and Schwartz, R. J. (1999). Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2.5. Development 126, 839-849
23. Rockman, H. A., Ross, R. S., Harris, A. N., Knowlton, K. U., Steinhelper, M. E., Field, L. J., Ross, J. J. and Chien, K. R. (1991). Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy [published erratum appears in Proc. Natl. Acad. Sci. USA 1991 88(21):9907]. Proc. Natl. Acad. Sci. USA 88, 8277-8281.
24. Ross, R. S., Navankasattusas, S., Harvey, R. P. and Chien, K. R. (1996). An HF-1a/HF-1b/MEF-2 combinatorial element confers cardiac ventricular specificity and established an anterior-posterior gradient of expression. Development 122, 1799-1809.
25. Schwartz, K., de, la, Bastie, D, Bouveret, P., Oliviero, P., Alonso, S. and Buckingham, M. (1986). Alpha-skeletal muscle actin mRNAs accumulate in hypertrophied adult rat hearts. Circ. Res. 59, 551-555.
26. Sepulveda, J. L., Belaguli, N., Nigam, V., Chen, C. V., Nemer, M. and Schwartz, R. J. (1998). GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol. Cell. Biol. 18, 3405-3415.
27. Shiojima, I., Komuro, I., Oka, T., Hiroi, Y., Mizuno, T., Takimoto, E. Monzen, K., Aikawa, R., Akazawa, H., Yamazaki, T., Kudoh., S. and Yazaki, Y. (1999). Context-dependent transcriptional cooperation mediated by cardiac transcriptionfactors Csx/Nkx2.5 and GATA-4. J. Biol. Chem. 274, 8231-8239.
28. Zhu, H., Garcia, A. V., Ross, R. S., Evans, S. M. and Chien, K. R. (1991). A conserved 28-base-pair element (HF-1) in the rat cardiac myosin light-chain-2 gene confers cardiac-specific and alpha-adrenergic-inducible expression in cultured neonatal rat myocardial cells. Mol. Cell. Biol. 11, 2273-2281.
29. Zou, Y., Evans, S., Chen, J., Kuo, H. C., Harvey, R. P. and Chien, K. R. (1997). CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. Development 124, 793-804.