Overexpression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia

Development

Volumn 122, Issue 11, 1996, Pages 3549-3556

  Cleaver, Ondine B ^a   Patterson, Kristin D ^a   Kriegt, Paul A ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Cardiac development; Heart field; Homeobox; Organogenesis; tinman; Xenopus; XNkx 2.5

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HOMEOBOX; NONHUMAN; PRIORITY JOURNAL; XENOPUS LAEVIS;

ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; GENES, HOMEOBOX; HEART; HOMEODOMAIN PROTEINS; HYPERPLASIA; IN SITU HYBRIDIZATION; MESODERM; MOLECULAR SEQUENCE DATA; MYOCARDIUM; TRANSCRIPTION FACTORS; XENOPUS LAEVIS; XENOPUS PROTEINS; ZEBRAFISH PROTEINS;

ANIMALIA; GALLUS GALLUS; INSECTA; VERTEBRATA; XENOPUS LAEVIS;

EID: 0029955134     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Azpiazu, N. and Frasen, M. (1993). tinman and bagpipe: two homeobox genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 7, 1325-1340.
2. Bodmer, R., Jan, L. Y. and Jan, Y. N. (1990). A new homeobox-oontaining gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila, Development 110, 661-669.
3. Bodmer, R. (1993). The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118, 719-729.
4. Bodner, M., Castrillo, J.-L., Theill, L. E., Deerinck, T., Ellisman, M. and Karin, M. (1988). The pituitary-specific transcription factor GHF-I is a homeobox-containing protein. Cell 55, 505-518.
5. Chambers, A. E., Logan, M., Kotecha, S., Towers, N., Sparrow, D. and Vlohtin. T. J. (1994). The RSRF/MEF2 protein SLI regulates cardiac muscle-specific transcription of a myosin light-chain gene in Xenopus embryos. Genes Dev. 8, 1324-1334.
6. Dale, L. and Slack, J. M. W. (1987). Fate map for the 32-cell stage of Xenopus laevis. Development 99, 527-551.
7. Dear, T. N., Colledge, W. H., Carlton, M. B., Lavenir, I., Larson, T., Smith, A. J., Warren, A. J., Evans, M. J., Sofroniew, M. V. and Rabbits, T. H. (1995). The Hoxll gene is essential for cell survival during spleen development. Development 121, 2909-2915.
8. Drysdale, T. A., Tonissen, K. F., Patterson, K. D., Crawford, M. J. and Krieg, P. A. (1994). Cardiac troponin I is a heart-specific marker in the Xenopus embryo: Expression during abnormal heart morphogenesis. Dev. Biol. 165, 432-441.
9. Evans, S. M., Yan, W., Murillo. M. P., Ponce, J. and Papalopulu, N. (1995). tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman. Development 121, 3889-3899.
10. Frain, M., Swart, G., Monad, P., Nicosia, A., Stampfli, S., Franck, R. and Cortese, R. (1989). The liver-specific transcription factor. LF-B1 contains a highly diverged homeobox DNA binding domain. Cell 59, 145-157.
11. Fu, Y. and Izumo, S. (1995). Cardiac myogenesis: Overexpression of XCsx2 or XMEF2A in whole Xenopus embryos induces the precocious expression of XAWCagene. Roux's Arch. Dev. Biol. 205, 198-202.
12. Grueneberg, D. A., Natesan, S., Alexandre, C. and Oilman. M. Z. (1992). Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of the serum response factor. Science 257, 1989-1095.
13. Guazzi, S., Price, M., De Felice, M., Damante, G., Mattel, M.-G. and Di Lauro, R. (1990). Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J. 9, 3631-3639.
14. Guazzi, S., Lonigro, R., Pintonello, L., Boncinelli, E., Di Lauro, R. and Mavilio, F. (1994). The thyroid transcription factor-1 gene is a candidate target for regulation by Hox proteins. EMBO J. 13, 339-3347.
15. Halder, G., Callaerts, P. and Gehring, W. J. (1995). Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science 267, 1788-1792.
16. Harland, R. (1991). In situ hybridization: An improved whole mount method for Xenopus embryos. Meth. Cell Biol. 36, 685-695.
17. Ingraham, H. A., Chen, R., Mangalam, H. J., Elsholtz, H. P., Flynn, S. E., Lin, C. R., Simmons, D. M., Swanson, L. and Rosenfeld, M. G. (1988). A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell 55, 519-529.
18. Ji, H., Sandberg, K., Zhang, Y. and Catt, K. J. (1993). Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor. Biochem, Biophys. Res. Commun. 194, 756-762.
19. Keller, R. E. (1976). Vital dye mapping of the gastrula and neurula of Xenopus laevis II. Prospective areas and morphogenetic movements of the deep layer. Dev. Biol. 51, 118-137.
20. Kim, Y. and Nirenberg, M. (1989). Drosophila NK-homeobox genes. Frac. Nat. Acad. Sci. USA 86, 7716-7720.
21. Komuro, I. and Izumo, S. (1993). Car. A murine homeobox-containing gene specifically expressed in the developing heart. Proc. Nat. Acad. Sci. USA 90, 8145-8149.
22. Krieg, P. A. and Melton, D. A. (1984). Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDN As. Nucl. Acids Res. 12, 7057-7070.
23. Lazarro, D., Price, M., De Felice, M. and Di Lauro, R. (1991). The transcription factor TTF-I is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development 113, 1093-1104.
24. Lints, T. J., Parsons, L. M., Hartley, L., Lyons, I. and Harvey, R. P. (1993). Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119, 419-431.
25. Logan, M. and Mohun, T. (1993). Induction of cardiac muscle differentiation in isolated animal pole expiants of Xenopus laevis embryos. Development 118, 865-875.
26. Lyons, I., Parsons, L. M., Hartley, L., Li, R., Andrews, J. E., Robb, L. and Harvey, R. P. (1995). Myogenic and morphogenetic detects in the heart tubes of murine embryos lacking the homeobox gene Nkx-2.5. Genes Dev. 9, 1654-1666.
27. McGinnis, W. and Krumlauf, R. (1992). Homeobox genes and axial patterning. Cell 68, 283-302.
28. Nascone, N. and Mercola, M. (1995). An inductive role for the endoderm in Xenopus cardiogenesis. Development 121, 515-523.
29. Nieuwkoop, P. D. and Faber, J. (1994). Normal Table of Xenopus laevis (Daudin), 2nd edn. Garland Publishing. Inc. New York.
30. Olson, E. N. (1993). Regulation of muscle transcription by the MyoD family: The heart of the matter. Circ. Res. 72, 1-6.
31. Price, M., Lazzaro, D., Pohl, T., Mattei, M.-G., Ruther, U., Olivo, J.-C., Duboule, D. and Di Lauro, R. (1992). Regional expression of the homeobox gene Nkx-2,2 in the developing mammalian forebrain. Neuron 8, 241-255.
32. Quiring, R., Walldorf, U., Kloter, U. and Gehring, W. J. (1995). Homology of the eyeless gene of Drosophila to the small eye gene in Mice and Aniridia in humans. Science 265, 785-789.
33. Roberts, C. W., Shutter, J. R. and Korsmeyer, S. J. (1994). Hux ll controls the genesis of the spleen. Nature 368, 747-749.
34. Sartorelli, V. and Kodes. L. (1992). Myocardial activation of the human cardiac a-actin promoter by helix-loop-helix proteins. Proc. Nat. Acad. Sci. USA 89, 4047-4051.
35. Sassoon, D., Lyons, W. E., Wright, V., Lin, A., Lassar, A., Weintraub, H. and Buckingham, M. (1989). Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis. Nature 341, 303-307.
36. Sassoon, D. A. (1993). Myogenic regulatory factors: Dissecting their role and regulation during vertebrate embryogenesis. Dev. Biol. 156, 11-23.
37. Sater, A. K. and Jacobson, A. G. (1989). The specification of heart mesoderm occurs during gastrulation in Xenopus laevis. Development 105, 821-830.
38. Sater, A. K. and Jacobson, A. G. (1990a). The role of the dorsal lip in the induction of heart mesoderm in Xenopus laevis. Development 108, 461-470.
39. Sater, A. K. and Jacobson, A. G. (1990b). The restriction of the heart morphogenetic field in Xenopus laevis. Dev. Biol. 140, 328-336.
40. Shultheiss, T. M., Xydas, S. and Lassar, A. B. (1995). Induction of avian cardiac myogenesisby anleriorendoderm. Development 121, 4203-4214.
41. Tonissen, K. F., Drysdale, T. A., Lints, T. J., Harvey, R. P. and Krieg, P. A. (1994). XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: Evidence for a conserved role in cardiac development. Dev. Biol. 162, 325-328.
42. Tonissen, K. F. and Krieg, P. A. (1994). Analysis of a variant Max sequence expressed in Xenopus laevis. Oncogene 9, 33-38.
43. Vize, P. D., Hemmati-Brivanlou, A., Harland, R. M. and Melton, D. A. (1991). Assays for gene function in developing Xenopus embryos. Merit. Cell Biol. 36, 367-387.
44. Vize, P. D. (1996). DNA sequences mediating the transcriptional responses of the Mix. 2 homeobox gene to mesoderm induction. Dev. Biol. 117, 226-231.