메뉴 건너뛰기




Volumn 20, Issue 8, 2000, Pages 2874-2879

Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DROSOPHILA; EMBRYO DEVELOPMENT; FERTILITY; GENE FUNCTION; GENE TARGETING; HOMEOBOX; HOMOZYGOTE; MOUSE; MULTIGENE FAMILY; MUTANT; NONHUMAN; ORGANOGENESIS; PHENOTYPE; PRIORITY JOURNAL;

EID: 0034115494     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.8.2874-2879.2000     Document Type: Article
Times cited : (39)

References (27)
  • 1
    • 0027237596 scopus 로고
    • Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
    • Azpiazu, N., and M. Frasch. 1993. tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 7:1325-1340.
    • (1993) Genes Dev. , vol.7 , pp. 1325-1340
    • Azpiazu, N.1    Frasch, M.2
  • 2
    • 0031959594 scopus 로고    scopus 로고
    • Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart
    • Biben, C., T. Hatzistavrou, and R. P. Harvey. 1998. Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart. Mech. Dev. 73:125-127.
    • (1998) Mech. Dev. , vol.73 , pp. 125-127
    • Biben, C.1    Hatzistavrou, T.2    Harvey, R.P.3
  • 3
    • 0027282774 scopus 로고
    • The gene tinman is required for specification of the heart and visceral muscles in Drosophila
    • Bodmer, R. 1993. The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118:719-729.
    • (1993) Development , vol.118 , pp. 719-729
    • Bodmer, R.1
  • 4
    • 0000071294 scopus 로고
    • A comprehensive classification of homeobox genes
    • D. Duboule (ed.). Oxford University Press, Oxford, England
    • Burglin, T. R. 1993. A comprehensive classification of homeobox genes, p. 25-71. In D. Duboule (ed.). Guidebook to the homeobox genes. Oxford University Press, Oxford, England.
    • (1993) Guidebook to the Homeobox Genes , pp. 25-71
    • Burglin, T.R.1
  • 5
    • 0025770278 scopus 로고
    • Planarian homeobox genes: Cloning, sequence analysis, and expression
    • Garcia-Fernandez, J., J. Baguna, and E. Salo. 1991. Planarian homeobox genes: cloning, sequence analysis, and expression. Proc. Natl. Acad. Sci. USA 88:7338-7342.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7338-7342
    • Garcia-Fernandez, J.1    Baguna, J.2    Salo, E.3
  • 6
    • 0030587603 scopus 로고    scopus 로고
    • NK-2 homeobox genes and heart development
    • Harvey, R. P. 1996. NK-2 homeobox genes and heart development. Dev. Biol. 178:203-216.
    • (1996) Dev. Biol. , vol.178 , pp. 203-216
    • Harvey, R.P.1
  • 8
    • 0025800182 scopus 로고
    • Deciphering the Hox code: Clues to patterning branchial regions of the head
    • Hunt, P., and R. Krumlauf. 1991. Deciphering the Hox code: clues to patterning branchial regions of the head. Cell 66:1075-1078.
    • (1991) Cell , vol.66 , pp. 1075-1078
    • Hunt, P.1    Krumlauf, R.2
  • 9
    • 0025941823 scopus 로고
    • Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
    • Kessel, M., and P. Gruss. 1991. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell 67:89-104.
    • (1991) Cell , vol.67 , pp. 89-104
    • Kessel, M.1    Gruss, P.2
  • 11
    • 0030057596 scopus 로고    scopus 로고
    • The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
    • Kimura, S., Y. Hara, T. Pineau, P. Fernandez-Salguero, C. H. Fox, J. M. Ward, and F. J. Gonzalez. 1996. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 10:60-69.
    • (1996) Genes Dev. , vol.10 , pp. 60-69
    • Kimura, S.1    Hara, Y.2    Pineau, T.3    Fernandez-Salguero, P.4    Fox, C.H.5    Ward, J.M.6    Gonzalez, F.J.7
  • 12
    • 0027184211 scopus 로고
    • Csx: A murine homeobox-containing gene specifically expressed in the developing heart
    • Komuro, I., and S. Izumo. 1993. Csx: a murine homeobox-containing gene specifically expressed in the developing heart. Proc. Natl. Acad. Sci. USA 90:8145-8149.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8145-8149
    • Komuro, I.1    Izumo, S.2
  • 13
    • 0026340586 scopus 로고
    • The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain
    • Lazzaro, D., M. Price, M. de Felice, and R. Di Lauro. 1991. The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development 113:1093-1104.
    • (1991) Development , vol.113 , pp. 1093-1104
    • Lazzaro, D.1    Price, M.2    De Felice, M.3    Di Lauro, R.4
  • 14
    • 0027700251 scopus 로고
    • Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
    • Lints, T. J., L. M. Parsons, L. Hartley, I. Lyons, and R. P. Harvey. 1993. Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119:419-431.
    • (1993) Development , vol.119 , pp. 419-431
    • Lints, T.J.1    Parsons, L.M.2    Hartley, L.3    Lyons, I.4    Harvey, R.P.5
  • 15
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
    • Lyons, I., L. M. Parsons, L. Hartley, R. Li, J. E. Andrews, L. Robb, and R. P. Harvey. 1995. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev. 9:1654-1666.
    • (1995) Genes Dev. , vol.9 , pp. 1654-1666
    • Lyons, I.1    Parsons, L.M.2    Hartley, L.3    Li, R.4    Andrews, J.E.5    Robb, L.6    Harvey, R.P.7
  • 16
    • 0027321548 scopus 로고
    • Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
    • Nagy, A., J. Rossant, R. Nagy, W. Abramow-Newerly, and J. C. Roder. 1993. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90:8424-8428.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8424-8428
    • Nagy, A.1    Rossant, J.2    Nagy, R.3    Abramow-Newerly, W.4    Roder, J.C.5
  • 17
    • 0027251031 scopus 로고
    • Lox10, a member of the NK-2 homeobox gene class, is expressed in a segmental pattern in the endoderm and in the cephalic nervous system of the leech Helobdella
    • Nardelli-Haefliger, D., and M. Shankland. 1993. Lox10, a member of the NK-2 homeobox gene class, is expressed in a segmental pattern in the endoderm and in the cephalic nervous system of the leech Helobdella. Development 118:877-892.
    • (1993) Development , vol.118 , pp. 877-892
    • Nardelli-Haefliger, D.1    Shankland, M.2
  • 18
    • 0031406027 scopus 로고    scopus 로고
    • Nkx2.6 expression is transiently and specifically restricted to the branchial region of pharyngeal-stage mouse embryos
    • Nikolova, M., X. Chen, and T. Lufkin. 1997. Nkx2.6 expression is transiently and specifically restricted to the branchial region of pharyngeal-stage mouse embryos. Mech. Dev. 69:215-218.
    • (1997) Mech. Dev. , vol.69 , pp. 215-218
    • Nikolova, M.1    Chen, X.2    Lufkin, T.3
  • 19
    • 0030899175 scopus 로고    scopus 로고
    • The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre-and postnatal mouse development
    • Pabst, O., A. Schneider, T. Brand, and H. H. Arnold. 1997 The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre-and postnatal mouse development. Dev. Dyn. 209:29-35.
    • (1997) Dev. Dyn. , vol.209 , pp. 29-35
    • Pabst, O.1    Schneider, A.2    Brand, T.3    Arnold, H.H.4
  • 20
    • 0032974961 scopus 로고    scopus 로고
    • Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen
    • Pabst, O., R. Zweigerdt, and H. H. Arnold. 1999. Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen. Development 126:2215-2225.
    • (1999) Development , vol.126 , pp. 2215-2225
    • Pabst, O.1    Zweigerdt, R.2    Arnold, H.H.3
  • 22
    • 0031571635 scopus 로고    scopus 로고
    • Chicken Nkx-2.8: A novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm
    • Reecy, J. M., M. Yamada, K. Cummings, D. Sosic, C. Y. Chen, G. Eichele, E. N. Olson, and R. J. Schwartz. 1997. Chicken Nkx-2.8: a novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm. Dev. Biol. 188:295-311.
    • (1997) Dev. Biol. , vol.188 , pp. 295-311
    • Reecy, J.M.1    Yamada, M.2    Cummings, K.3    Sosic, D.4    Chen, C.Y.5    Eichele, G.6    Olson, E.N.7    Schwartz, R.J.8
  • 24
    • 0031843386 scopus 로고    scopus 로고
    • Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
    • Sussel, L., J. Kalamaras, O. C. U. J. Hartigan, J. J. Meneses, R. A. Pedersen, J. L. Rubenstein, and M. S. German. 1998. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125:2213-2221.
    • (1998) Development , vol.125 , pp. 2213-2221
    • Sussel, L.1    Kalamaras, J.2    Hartigan, O.C.U.J.3    Meneses, J.J.4    Pedersen, R.A.5    Rubenstein, J.L.6    German, M.S.7
  • 25
    • 0032907924 scopus 로고    scopus 로고
    • The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development
    • Tanaka, M., Z. Chen, S. Bartunkova, N. Yamasaki, and S. Izumo. 1999. The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development 126:1269-1280.
    • (1999) Development , vol.126 , pp. 1269-1280
    • Tanaka, M.1    Chen, Z.2    Bartunkova, S.3    Yamasaki, N.4    Izumo, S.5
  • 27
    • 0025780879 scopus 로고
    • Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
    • Tybulewicz, V. L., C. E. Crawford, P. K. Jackson, R. T. Bronson, and R. C. Mulligan. 1991. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65:1153-1163.
    • (1991) Cell , vol.65 , pp. 1153-1163
    • Tybulewicz, V.L.1    Crawford, C.E.2    Jackson, P.K.3    Bronson, R.T.4    Mulligan, R.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.