Adult cardiac stem cells are multipotent and support myocardial regeneration

Cell

Volumn 114, Issue 6, 2003, Pages 763-776

  Beltrami, Antonio P ^a   Barlucchi, Laura ^a   Torella, Daniele ^a   Baker, Mathue ^a   Limana, Federica ^a   Chimenti, Stefano ^a   Kasahara, Hideko ^b   Rota, Marcello ^a   Musso, Ezio ^a   Urbanek, Konrad ^a   Leri, Annarosa ^a   Kajstura, Jan ^a   Nadal Ginard, Bernardo ^a   Anversa, Piero ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUSION; CELL REGENERATION; CELL SUBPOPULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HEART MUSCLE; IN VIVO STUDY; MOLECULAR CLONING; MUSCLE CELL; MUSCLE DEVELOPMENT; MUSCLE REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE; STEM CELL;

ANIMALIA;

EID: 10744228523     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00687-1     Document Type: Article

References (44)

1. Alison M.R., Poulsom R., Otto W.R., Vig P., Brittan M., Direkze N.C., Prestin S.L., Wright N.A. Plastic adult stem cells. will they graduate from the school of hard knocks? J. Cell Sci. 116:2003;599-603.
2. Anderson D.J., Gage F.H., Weissman I.L. Can stem cells cross lineage boundaries? Nat. Med. 7:2001;393-395.
3. Anversa P., Nadal-Ginard B. Cardiac chimerism. methods matter Circulation. 106:2002;e129-e131. a.
4. Anversa P., Nadal-Ginard B. Myocyte renewal and ventricular remodeling. Nature. 415:2002;240-243. b.
5. Assmus B., Schachinger V., Teupe C., Britten M., Lehmann R., Dobert N., Grunwald F., Aicher A., Irbich C., Martin H.et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation. 106:2002;3009-3017.
6. Beltrami A.P., Urbanek K., Kajstura J., Yan S.M., Finato N., Bussani R., Nadal-Ginard B., Silvestri F., Leri A., Beltrami C.A., Anversa P. Evidence that human cardiac myocytes divide after myocardial infarction. N. Engl. J. Med. 344:2001;1750-1757.
7. Broudy V.C. Stem cell factor and hematopoiesis. Blood. 90:1997;1345-1364.
8. Chien K.R., Olson E.N. Converging pathways and principles in heart development and disease. Cell. 110:2002;153-162.
9. Frangogiannis N.G., Perrard J.L., Mendoza L.H., Burns A.R., Lindsey M.L., Ballantyne C.M., Michael L.H., Smith C.W., Entman M.L. Stem cell factor induction is associated with mast cell accumulation after canine myocardial ischemia and reperfusion. Circulation. 98:1998;687-698.
10. Gage F.H. Mammalian neural stem cells. Science. 287:2002;1433-1438.
11. Glaser R., Lu M.M., Narula N., Epstein J.A. Smooth muscle cells, but not myocytes, of host origin in transplanted human hearts. Circulation. 106:2002;17-19.
12. Hellermann J.P., Jacobsen S.J., Gersh B.J., Rodeheffer R.J., Reeder G.S., Roger V.L. Heart failure after myocardial infarction. a review Am. J. Med. 113:2002;324-330.
13. Jiang Y., Jahagirdar B.N., Reinhardt R.L., Schwartz R.E., Keene C.D., Ortiz-Gonzalez X.R., Reyes M., Lenvik T., Lund T., Blackstad M.et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature. 418:2002;41-49.
14. Kajstura J., Leri A., Finato N., DiLoreto C., Beltrami C.A., Anversa P. Myocyte proliferation in end-stage cardiac failure. Proc. Natl. Acad. Sci. USA. 95:1998;8801-8805.
15. Kasahara H., Bartunkova S., Schinke M., Tanaka M., Izumo S. Cardiac and extracardiac expression of Csx/Nkx2.5 homeodomain protein. Circ. Res. 82:1998;936-946.
16. Kondo M., Wagers A.J., Manz M.G., Prohaska S.S., Scherer D.C., Beilhack G.F., Shizuru J.A., Weissman I.L. Biology of hematopoietic stem cells and progenitors. implications for clinical application Annu. Rev. Immunol. 21:2003;759-806.
17. Kosaka M., Kodama R., Eguchi G. In vitro culture system for iris-pigmented epithelial cells for molecular analysis of transdifferentiation. Exp. Cell Res. 245:1998;245-251.
18. Krause D.S., Theise N.D., Collector M.I., Henegariu O., Hwang S., Gardner R., Neutzel S., Sharkis S.J. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell. 105:2001;369-377.
19. Kunisada T., Yoshida H., Yamazaki H., Miyamoto A., Hemmi H., Nishimura E., Shultz L.D., Nishikawa S., Hayashi S. Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors. Development. 125:1998;2915-2923.
20. Laflamme M.A., Myerson D., Saffitz J.E., Murry C.E. Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts. Circ. Res. 90:2002;634-640.
21. MacLellan W.R., Schneider M.D. Genetic dissection of cardiac growth control pathways. Annu. Rev. Physiol. 62:2000;289-319.
22. Mahmud N., Devine S.M., Weller K.P., Parmar S., Sturgeon C., Nelson M.C., Hewett T., Hoffman R. The relative quiescence of hematopoietic stem cells in nonhuman primates. Blood. 97:2001;3061-3068.
23. McDonnell T.J., Oberpriller J.O. The response of the atrium to direct mechanical wounding in the adult heart of the newt, Notophthalmus viridescens. An electron-microscope and autoradiographic study. Cell Tissue Res. 235:1984;583-592.
24. Mikawa T. Cardiac lineages. Harvey R.P., Rosenthal N. Heart Development. 1999;Academic Press, San Diego. 19-49.pp.
25. Molkentin J.D., Lin Q., Duncan S.A., Olson E.N. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 11:1997;1061-1072.
26. Morrison S.J., Wandycz A.M., Akashi K., Globerson A., Weissman I.L. The aging of hematopoietic stem cells. Nat. Med. 2:1996;1011-1019.
27. Morrison S.J., Wandycz A.M., Hemmati H.D., Wright D.E., Weissman I.L. Identification of a lineage of multipotent hematopoietic progenitors. Development. 124:1997;1929-1939.
28. Muller P., Pfeiffer P., Koglin J., Schafers H.J., Seeland U., Janzen I., Urbschat S., Bohm M. Cardiomyocytes of noncardiac origin in myocardial biopsies of human transplanted hearts. Circulation. 106:2002;31-35.
29. Nadal-Ginard B., Kajstura J., Leri A., Anversa P. Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ. Res. 92:2003;139-150.
30. Nadin, B.M., Goodell, M.A., and Hirschi, K.K. (2003). Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood, in press. Published online June 12, 2003. 10.1182/blood-2003-01-0118 .
31. Orlic D., Kajstura J., Chimenti S., Jakoniuk I., Anderson S.M., Li B., Pickel J., McKay R., Nadal-Ginard B., Bodine D.M.et al. Bone marrow cells regenerate infarcted myocardium. Nature. 410:2001;701-705.
32. Perin E.C., Dohmann H.F., Borojevic R., Silva S.A., Sousa A.L., Mesquita C., Rossi M.I., Carvalho A.C., Dutra H.S., Dohmann H.J.et al. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation. 107:2003;2294-2302.
33. Quaini F., Urbanek K., Beltrami A.P., Finato N., Beltrami C.A., Nadal-Ginard B., Kajstura J., Leri A., Anversa P. Chimerism of the transplanted heart. N. Engl. J. Med. 346:2002;5-15.
34. Rosenthal N. Prometheus's vulture and the stem cell promise. N. Engl. J. Med. 346:2003;267-274.
35. Rumyantsev P.P., Broisov A. DNA synthesis in myocytes from different myocardial compartments of young rats in norm, after experimental infarction and in vitro. Biomed. Biochim. Acta. 46:1987;S610-S615.
36. Scholzen T., Gerdes J. The Ki-67 protein. from the known to the unknown J. Cell. Physiol. 182:2000;311-322.
37. Sellers S.E., Tisdale J.F., Agricola B.A., Metzger M.E., Donahue R.E., Dunbar C.E., Sorrentino B.P. The effect of multidrug-resistance 1 gene versus neo transduction on ex vivo and in vivo expansion of rhesus macaque hematopoietic repopulating cells. Blood. 97:2001;1888-1891.
38. Strauer B.E., Brehm M., Zeus T., Kostering M., Hernandez A., Sorg R.V., Kogler G., Wernet P. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation. 106:2002;1913-1918.
39. Suslov O.N., Kukekov V.G., Ignatova T.N., Steindler D.A. Neural stem cell heterogeneity demonstrated by molecular phenotyping of clonal neurospheres. Proc. Natl. Acad. Sci. USA. 99:2002;14506-14511.
40. Teyssier-Le Discorde M., Prost S., Nandrot E., Kirszenbaum M. Spatial and temporal mapping of c-kit and its ligand, stem cell factor expression during human embryonic haemopoiesis. Br. J. Haematol. 107:1999;247-253.
41. Tropepe V., Sibilia M., Ciruna B.G., Rossant J., Wagner E.F., van der Koo D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev. Biol. 208:1999;166-168.
42. Tse H.F., Kwong Y.L., Chan J.K., Lo G., Ho C.L., Lau C.P. Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet. 361:2003;47-49.
43. Urbanek K., Quaini F., Tasca G., Torella D., Castaldo C., Nadal-Ginard B., Leri A., Kajstura J., Quaini E., Anversa P. Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proc. Natl. Acad. Sci. USA. 100:2003;10440-10445. . Published online August 19, 2003 10.1073/pnas/1832855100.
44. Weissman I.L., Anderson D.J., Gage F. Stem and progenitor cells. origins, phenotypes, lineage commitments, and transdifferentiations Annu. Rev. Cell Dev. Biol. 17:2001;387-403.