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Volumn 28, Issue 3, 2001, Pages 276-280

Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONGENITAL HEART DISEASE; HEART DEVELOPMENT; HEART MUSCLE CELL; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION;

EID: 0034931034     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/90123     Document Type: Article
Times cited : (499)

References (29)
  • 3
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2-5
    • (1995) Genes Dev. , vol.9 , pp. 1654-1666
    • Lyons, I.1
  • 4
    • 0032479573 scopus 로고    scopus 로고
    • Congenital heart disease caused by mutations in the transcription factor NKX2-5
    • (1998) Science , vol.281 , pp. 108-111
    • Schott, J.J.1
  • 5
    • 0033430230 scopus 로고    scopus 로고
    • Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways
    • (1999) J. Clin. Invest. , vol.104 , pp. 1567-1573
    • Benson, D.W.1
  • 6
    • 1842413728 scopus 로고    scopus 로고
    • Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
    • (1997) Nature Genet. , vol.15 , pp. 21-29
    • Li, Q.Y.1
  • 7
    • 0030636780 scopus 로고    scopus 로고
    • Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome
    • (1997) Nature Genet. , vol.15 , pp. 30-35
    • Basson, C.T.1
  • 10
    • 0032850596 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7096-7105
    • Monzen, K.1
  • 11
    • 0027282774 scopus 로고
    • The gene tinman is required for specification of the heart and visceral muscles in Drosophila
    • (1993) Development , vol.118 , pp. 719-729
    • Bodmer, R.1
  • 12
    • 0027237596 scopus 로고
    • Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
    • (1993) Genes Dev. , vol.7 , pp. 1325-1340
    • Azpiazu, N.1    Frasch, M.2
  • 13
    • 0031805612 scopus 로고    scopus 로고
    • Vertebrate homologs of tinman and bagpipe: Roles of the homeobox genes in cardiovascular development
    • (1998) Dev. Genet. , vol.22 , pp. 239-249
    • Tanaka, M.1
  • 15
    • 0033912859 scopus 로고    scopus 로고
    • Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease
    • (2000) J. Clin. Invest , vol.106 , pp. 299-308
    • Kasahara, H.1
  • 16
    • 0032975539 scopus 로고    scopus 로고
    • Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient
    • (1999) Jpn. Circ. J. , vol.63 , pp. 425-426
    • Hosoda, T.1
  • 17
    • 0000342273 scopus 로고    scopus 로고
    • Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements
    • (1996) Dev. Genet. , vol.19 , pp. 119-130
    • Chen, C.Y.1
  • 20
    • 0031844382 scopus 로고    scopus 로고
    • The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3120-3129
    • Lee, Y.1
  • 21
    • 0033583178 scopus 로고    scopus 로고
    • Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4
    • (1999) J. Biol. Chem. , vol.274 , pp. 8231-8239
    • Shiojima, I.1
  • 24
    • 0033614374 scopus 로고    scopus 로고
    • Tbx5 and Tbx4 genes determine the wing/leg identity of limb buds
    • (1999) Nature , vol.398 , pp. 810-814
    • Takeuchi, J.K.1
  • 28
    • 0039706410 scopus 로고    scopus 로고
    • Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor
    • (1997) Nature , vol.389 , pp. 884-888
    • Muller, C.W.1    Herrmann, B.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.