Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm

Development

Volumn 125, Issue 8, 1998, Pages 1447-1456

  Onichtchouk, Darya ^a   Glinka, Rei ^a   Niehrs, Christof ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

BMP 4; Homeobox; Mesoderm; Organizer; Xenopus; Xvent 1; Xvent 2

Indexed keywords

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO AXIS; EMBRYO PATTERN FORMATION; GENE FUNCTION; GENETIC TRANSCRIPTION; HOMEOBOX; MESODERM; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; REPRESSOR GENE; SIGNAL TRANSDUCTION; XENOPUS;

ANIMALS; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; DNA PRIMERS; DNA-BINDING PROTEINS; EMBRYO, NONMAMMALIAN; EMBRYONIC INDUCTION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MESODERM; NERVOUS SYSTEM; POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; SMAD PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOPUS; XENOPUS PROTEINS;

AMPHIBIA; ANIMALIA; REPTILIA; VERTEBRATA;

EID: 0031812546     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Bellefroid, E. J., Bourguignon, C., Hollemann, T., Ma, Q., Anderson, D. J., Kintner, C. and Pieler, T. (1996). X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation. Cell 87, 1191-1202.
2. Blitz, I. L. and Cho, K. W. Y. (1995). Anterior neuroectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle. Development 121, 993-1004.
3. Christian, J. L. and Moon, R. T. (1993). Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev. 7, 13-28.
4. Clement, J. H., Fettes, P., Knöchel, S., Lef, J. and Knöchel, W. (1995). Bone morphogenetic protein 2 in the early development of Xenopus laevis. Mech. Dev. 52, 357-370.
5. Conlon, F., Sedgwick, S. G., Weston, K. M. and Smith, J. C. (1996). Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm. Development 122, 2427-2435.
6. De Celis, J. F., Barrio, R. and Kafatos, F. C. (1996). A gene complex acting downstream of dpp in Drosophila wing morphogenesis. Nature 381, 421-424.
7. De Robertis, E. M. and Sasai, Y. (1996). A common plan for dorsoventral patterning in Bilateria. Nature 380, 37-40.
8. Dent, J. A., Polson, A. G. and Klymkowsky, M. W. (1989). A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus. Development 105, 61-74.
9. Dosch, R., Gawantka, V., Delius, H., Blumenstock, C. and Niehrs, C. (1997). Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus. Development 124, 2325-2334.
10. Fainsod, A., Steinbeisser, H. and De, R. E. (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J. 13, 5015-5025.
11. Ferguson, E. L. and Anderson, K. V. (1992). Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461.
12. Ferreiro, B., Artinger, M., Cho, K. W., Niehrs, C. (1998). Antimorphic goosecoids. Development 125, 1347-1359.
13. Friedman, A. D., Triezenberg, S. J. and McKnight, S. L. (1988). Expression of a truncated viral trans-activator selectively impedes lytic infection by its cognate virus. Nature 335, 452-454.
14. Gawantka, V., Delius, H., Hirschfeld, K., Blumenstock, C. and Niehrs, C. (1995). Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1. EMBO J. 14, 6268-6279.
15. Glinka, A., Wu, W., Onichtchouk, D., Blumenstock, C. and Niehrs, C. (1997). Head induction by simultaneous repression of Bmp and wnt signalling in Xenopus. Nature 389, 517-519.
16. Graff, J. M., Thies, R. S., Song, J. J., Celeste, A. J. and Melton, D. A. (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.
17. Grimm, S. and Pflugfelder, G. O. (1996). Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless. Science 271, 1601-1604.
18. Han, K. and Manley, J. L. (1993). Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain. Genes Dev. 7, 491-503.
19. Hemmati-Brivanlou, A. and Melton, D. A. (1994). Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 77, 273-281.
20. Hemmati-Brivanlou, A. and Melton, D. (1997). Vertebrate embryonic cells will become nerve cells unless told otherwise. Cell 88, 13-17.
21. Hogan, B. M. (1996). Bone morphogenetic proteins:multifunctional regulators of vertebrate development. Genes Dev. 10, 1580-1594.
22. Hoppler, S., Brown, J. D. and Moon, R. T. (1996). Expression of a dominant-negative wnt blocks induction of MyoD in Xenopus embryos. Genes Dev. 10, 2805-2817.
23. Jaynes, J. B. and O' Farrell, P. H. (1991). Active repression of transcription by the Engrailed homeodomain protein. EMBO J. 10, 1427-1433.
24. Kao, K. R. and Elinson, R. P. (1988). The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos. Dev. Biol. 127, 64-77.
25. Kintner, C. R. and Brockes, J. P. (1984). Monoclonal antibodies recognize blastemal cells derived from differentiating muscle in newt limb regeneration. Nature 308, 67-69.
26. Knecht, A. and Harland, R. M. (1997). Mechanisms of dorsal-ventral paterning in noggin-induced neural tissue. Development 124, 2477-2488.
27. Ladher, R., Mohun, T. J., Smith, J. C. and Snape, A. M. (1996). Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4. Development 122, 2385-2394.
28. Lecuit, T., Brook, W. J., Ng, M., Calleja, M., Sun, H. and Cohen, S. (1996). Two distinct mechanisms for long-range patterning by decapentaplegic in the Drosophua wing. Nature 381, 387-392.
29. Lecuit, T. and Cohen, S. M. (1997). Proximal-distal axis formation in the Drosophila leg. Nature 388, 139-145.
30. Lemaire, P. (1996). The coming of age of ventralising homeobox genes in amphibian development. BioEssays 18, 701-704.
31. Lemaire, P., Garrett, N. and Gurdon, J. B. (1995). Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81, 85-94.
32. Lemaire, P. and Kodjabachian, L. (1996). The vertebrate organizer: structure and molecules. Trends Genet. 12, 525-531.
33. Leyns, L., Bouwmeester, T., Kim, S.-H., Piccolo, S. and De Robertis, E. M. (1997). Frzb-1 is a secreted antagonist of wnt-signals expressed in the Spemann organizer. Cell 88, 747-756.
34. Liem, K. F., Tremml, G., Roelink, H. and Jessell, T. M. (1995). Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82, 969-979.
35. Massague, J., Hata, A. and Liu, F. (1997). TGF-beta signalling through the Smad pathway. Trends Cell Biol. 7, 187-192.
36. Mayor, R. (1995). Induction of the prospective neural crest of Xenopus. Development 121, 767-777.
37. Mead, P. E., Brivanlou, I. H., Kelley, C. M. and Zon, L. I. (1996). BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.l. Nature 382, 357-360.
38. Miklos, G. L. and Rubin, G. M. (1996). The role of the genome project in determining gene function: insights from model organisms. Cell 86, 521-529.
39. Mohun, T. J., Brennan, S. and Gurdon, J. B. (1984). Region-specific regulation of the actin multi-gene family in early amphibian embryos. Philos. Trans R. Soc. Lond. B Biol. Sci. 307, 337-42.
40. Neave, B., Holder, N. and Patient, R. (1997). A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish. Mech. Dev. 62, 103-246.
41. Nellen, D., Burke, R., Struhl, G. and Basler, K. (1996). Direct and long-range action of a dpp morphogen gradient. Cell 85, 357-368.
42. Niehrs, C., Keller, R., Cho, K. W. and De Robertis, E. M. (1993). The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell 72, 491-503.
43. Niehrs, C., Steinbeisser, H. and De Robertis, E. M. (1994). Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid. Science 263, 817-820.
44. Onichtchouk, D., Gawantka, V., Dosch, R., Delius, H., Hirschfeld, K., Blumenstock, C. and Niehrs, C. (1996). The Xvent-2 homeobox gene is part of the BMP-4 signaling pathway controling dorsoventral patterning of Xenopus mesoderm. Development 122, 3045-3053.
45. Papalopulu, N. and Kintner, C. (1996). A Xenopus gene, Xbr-1. defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye. Dev. Biol. 174, 104-114.
46. Rosa, F. M. (1989). Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. Cell 57, 965-974.
47. Ruiz i Altaba, A. and Melton, D. A. (1989a). Bimodal and graded expression of the Xenopus homeobox gene Xhox3 during embryonic development. Development 106, 173-183.
48. Ruiz i Altaba, A. and Melton, D. A. (1989b). Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis. Cell 51, 317-326.
49. Rupp, R. A. and Weintraub, H. (1991). Ubiquitous MyoD transcription at the midblastula transition precedes induction-dependent MyoD expression in presumptive mesoderm of X. laevis. Cell 65, 927-937.
50. Sasai, Y., Lu, B., Steinbeisser, H. and De Robertis, E. M. (1995). Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.
51. Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M. (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.
52. Schmidt, J. E., vonDassow, G. and Kimelman, D. (1996). Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox. Development 122, 1711-1721.
53. Smith, J. C., Price, B. M., Green, J. B., Weigel, D. and Herrmann, B. G. (1991). Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
54. Sturtevant, M. A., Biehs, B., Marin, E. and Bier, E. (1997). The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing. Development 124, 21-32.
55. Suzuki, A., Thies, R. S., Yamaji, N., Song, J. J., Wozney, J. M., Murakami, K. and Ueno, N. (1994). A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc. Natl Acad. Sci. USA 91, 10255-10259.
56. Thomsen, G., Woolf, T., Whitman, M., Sokol, S., Vaughan, J., Vale, W. and Melton, D. A. (1990). Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63, 485-493.
57. Tidman-Ault, C., Dirksen, M. L. and Jamrich, M. (1996). A novel homeobox gene PV.1 mediates induction of ventral mesoderm in Xenopus embryos. Proc. Natl. Acad. Sci. USA 93, 6415-6420.
58. Tonegawa, A., Funayama, N., Ueno, N. and Takahashi, Y. (1997). Mesodermal subdivision along the mediolateral axis in chicken controlledby different concentrations of BMP-4. Development 124, 1975-1984.
59. Walmsley, M. E., Guille, M. J., Bertwistle, D., Smith, J. C., Pizzey, J. A. and Patient, R. K. (1994). Negative control of Xenopus GATA-2 by activin and noggin with eventual expression in precursors of the ventral blood islands. Development 120, 2519-2529.
60. Wang, S., Krinks, M., Lin, K., Luyten, F. P. and Moos, M. (1997). Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8. Cell 88, 757-766.
61. Wang, Y., O'Malley Jr., B. W., Tsai, S. Y. and O'Malley, B. W. (1994). A regulatory system for use in gene transfer. Proc. Natl. Acad. Sci. USA 91, 8180-8184.
62. Wharton, K. A., Ray, R. P. and Gelbart, W. M. (1993). An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822.
63. Wilson, P. A. and Hemmati-Brivanlou, B. A. (1995). Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333.