The wingless signaling pathway is directly involved in Drosophila heart development

Developmental Biology

Volumn 177, Issue 1, 1996, Pages 104-116

  Park, Maiyon ^a   Wu, Xiushan ^a,c   Golden, Krista ^a   Axelrod, Jeffrey D ^b   Bodmer, Rolf ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT;

ARTICLE; DROSOPHILA; EMBRYO SEGMENTATION; GENE; GENE EXPRESSION; HEART DEVELOPMENT; HOMEOBOX; MESODERM; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0030578428     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1996.0149     Document Type: Article

References (62)

1. Axelrod, J. D., Matsuno, K., Artavanis-Tsakonas, S., and Perrimon, N. (1996). Interaction between Wingless and Notch signalling pathways mediated by Dishevelled. Science 271, 1826-1832.
2. Azpiazu, N., and Frasch, M. (1993). Tinman and bagpipe: two homeobox genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 7, 1325-1340.
3. Baker, N. (1987). Molecular cloning of sequences from wingless, a segment polarity gene in Drosophila: The spatial distribution of a transcript in embryos. EMBO J. 6, 1765-1773.
4. Bate, M. (1993). The mesoderm and its derivatives. In "The Developmental Biology of Drosophila melanogaster," (M. Bate and A. Martinez Arias, Eds.), Vol. 2, pp. 1013-1090. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
5. Baylies, M. K., Martinez Arias, A., and Bate, M. (1995). wingless is required for the formation of a subset of muscle founder cells during Drosophila embryogenesis. Development 121, 3829-3837.
6. Bejsovec, A., and Martinez Arias, A. (1991). Roles of wingless in patterning the larval epidermis of Drosophila. Development 113, 471-485.
7. Bodmer, R., Jan, L. Y., and Jan, Y. N. (1990). A new homeobox-containing gene, msh-2 (tinman), is transiently expressed early during mesoderm formation in Drosophila. Development 110, 661-669.
8. Bodmer, R. (1993). The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118, 719-729.
9. Bodmer, R. (1995). Heart development in Drosophila and its relationship to vertebrate systems. Trends Cardiovasc. Med. 5, 21-27.
10. Bour, B. A., O'Brien, M. A., Lockwood, W. L., Goldstein, E. S., Bodmer, R., Taghert, P. H., Abmayr, S. M., and Nguyen, H. T. (1995). Drosophila MEF2, a transcription factor that is essential for myogenesis. Genes Dev. 9, 730-741.
11. Bourouis, M., Moore, P., Ruel, L., Grau, Y., Heitzler, P., and Simpson, P. (1990). An early embryonic profuct of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/ cdc2+ subfamily. EMBO J. 9, 2877-2884.
12. Cadigan, K. M., Grossniklaus, U., and Gehring, W. J. (1994). Localized expression of sloppy paired protein maintains the polarity of Drosophila parasegments. Genes Dev. 8, 899-913.
13. Chou, T. B., and Perrimon, N. (1992). Use of a yeast site-specific recombinase to produce female germ line chimeras in Drosophila. Genetics 131, 643-653.
14. Chu-LaGraff, Q., and Doe, C. Q. (1993). Neuroblast specification and formation regulated by wingless in the Drosophila CNS. Science 261, 1594-1597.
15. Evans, S. M., Yan, W., Murillo, M. P., Ponce, J., and Papalopulu, N. (1995). Tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: Xnkx-2.3, a second vertebrate homologue of tinman. Development 121, 3889-3899.
16. Francois, V., Solloway, M., O'Neil, J. W., Emery, J., and Bier, E. (1994). Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. Genes Dev. 8, 2602-2616.
17. Frasch, M., Hoey, T., Rushlow, C., Doyle, H., and Levine, M. (1987). Characterization and localization of the even-skipped protein of Drosophila. EMBO J. 6, 749-759.
18. Frasch, M. (1995). Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. Nature 374, 464-467.
19. Govind, S., and Steward, R. (1991). Dorsoventral pattern formation in Drosophila. Trends Genet. 7, 119-125.
20. Grossniklaus, U., Pearson, R. K., and Gehring, W. J. (1992). The Drosophila sloppy paired locus encodes two proteins involved in segmentation that show homology to mammalian transcription factors. Genes Dev. 6, 1030-1051.
21. Ingham, P. W. (1993). Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo. Nature 366, 560-562.
22. Heemskerk, J., and DiNardo, S. (1994). Drosophila hedgehog acts as a morphogen in cellular patterning. Cell 76, 449-460.
23. Karpen, G. H., and Spradling, A. C. (1992). Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P-element insertional mutagenesis. Genetics 132, 737-753.
24. Kiehart, D. P., and Feghali, R. (1986). Cytoplasmic myosin from Drosophila melanogaster. J. Cell Biol. 103, 1517-1525.
25. + channels by interaction with a family of membrane-associated guanylate kinases. Nature 378, 85-88.
26. Klingensmith, J., Nusse, R., and Perrimon, N. (1994). The Drosophila segment polarity gene dishevelled encodes a novel protein required for the response to the wingless signal. Genes Dev. 8, 118-130.
27. Komuro, I., and Izumo, S. (1993). csx, a murine homeobox-containing gene specifically expressed in the developing heart. Proc. Natl. Acad. Sci. USA 90, 8145-1949.
28. Lai, Z., Fortini, M. E., and Rubin, G. M. (1991). The embryonic expression patterns of zfh-1 and zfh-2, two Drosophila genes encoding novel zinc-finger homeodomain proteins. Mech Dev. 34, 123-134.
29. Lawrence, P. A., Bodmer, R., and Vincent, J. P. (1995). Segmental patterning of heart precursors in Drosophila. Development 121, 4303-4308.
30. Lilly, B., Zhao, B., Ranganayakulu, G., Patterson, B. M., Schulz, R. A., and Olson, E. N. (1995). Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila. Science 267, 688-693.
31. Lints, T. J., Parsons, L. M., Hartley, L., Lyons, I., and Harvey, R. (1993). Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119, 419-431.
32. Lyons, I., Parsons, L. M., Hartley, L., Li, R., Andrews, J. E., Robb, L., and Harvey, R. P. (1995). Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2-5. Genes Dev. 9, 1654-1666.
33. Noordermeer, J., Johnston, P., Rijsewijk, F., Nusse, R., and Lawrence, P. (1992). The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development 116, 711-719.
34. Noordermeer, J., Klingensmith, J., Perrimon, N., and Nusse, R. (1994). dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature 367, 80-83.
35. Nusse, R., and Varmus, H. E. (1992). Wnt genes. Cell 69, 1073-1087.
36. Nusslein-Volhard, C. E., Wieschaus, E., and Kluding, H. (1984). Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome. Roux's Arch. Dev. Biol. 193, 267-282.
37. Oda, H., Uemura, T., Shiomi, K., Nagafuchi, A., Tsukita, S., and Takeichi, M. (1993). Identification of a Drosophila homologue of -catenin and its association with the armadillo protein. J. Cell Biol. 121, 1133-1140.
38. Orenic, T. V., Slusarski, D. C., Kroll, K. L., and Holmgren, R. A. (1990). Cloning and characterization of the segment polarity gene cubitus interruptus dominant of Drosophila. Genes Dev. 4, 1053-1067.
39. Patel, N., Snow, P. M., and Goodman, C. S. (1987). Characterization and cloning of fasciclin III: a glycoprotein expressed on a subset of neurons and axon pathways in Drosophila. Cell 48, 975-988.
40. Peifer, M., and Wieschaus, E. (1990). The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human Plakoglobin. Cell 63, 1167-1178.
41. Peifer, M., and Bejsovec, A. (1992). Knowing your neighbor: cell interactions determine intrasegmental pattering in Drosophila. Trends Genet. 8, 243-249.
42. Peifer, M., Sweeton, D., Casey, M., and Wieschaus, E. (1994). wingless signal and zeste-white 3 kinase trigger opposing changes in the intracellular distribution of armadillo. Development 120, 369-380.
43. Perrimon, N. (1994). The genetic basis of patterned baldness in Drosophila. Cell 76, 781-784.
44. Poulson, D. F. (1950). Histogenesis, organogenesis and differentiation in the embryo of Drosophila melanogaster. In "The Biology of Drosophila," (M. Demerec, Ed.), pp. 168-274. Wiley, New York.
45. Riggleman, B., Schedl, P., and Weischaus, E. (1990). Spatial expression of the Drosophila segment polarity gene armadillo is post-transcriptionally regulated by wingless. Cell 63, 549-560.
46. Rugendorff, A., Younossi-Hartenstein, A., and Hartenstein, V. (1994). Embryonic origin and differentiation of the Drosophila heart. Roux's Arch Dev. Biol. 203, 266-280.
47. Siegfried, E., Perkins, L. A., Capaci, T. M., and Perrimon, N. (1990). Putative protein kinase product of the Drosophila segment-polarity gene zeste-white 3. Nature 345, 825-829.
48. Siegfried, E., Chou, T. B., and Perrimon, N. (1992). wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell 71, 1167-1179.
49. Siegfried, E., Wilder, E. L., and Perrimon, N. (1994). Components of wingless signalling in Drosophila. Nature 367, 76-79.
50. Simpson, P. (1983). Maternal-zygotic gene interactions involving the dorsal-ventral axis in Drosophila embryos. Genetics 105, 615-632.
51. Staehling-Hampton, K., Hoffmann, F. M., Baylies, M. K., Rushton, E., and Bate, M. (1994). dpp induces mesodermal gene expression in Drosophila. Nature 372, 783-786.
52. St. Johnston, D., and Nusslein-Volhard, C. (1992). The origin of pattern and polarity in the Drosophila embryo. Cell 68, 201-219.
53. Tabata, T., and Kornberg, T. B. (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.
54. Tautz, D., and Pfeifle, D. (1989). A nonradioactive in situ hybridization method for the localization of specific RNAs in Drosophila reveals a translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
55. Thisse, B., Stoetzel, C., Messal, M. E., and Perrin-Schmitt, F. (1987). Genes of the Drosophila dorsal group control the specific expression of the zygotic gene twist in presumptive mesodermal cells. Genes Dev. 1, 709-715.
56. Thisse, B., Stoetzel, C., Gorositiza-Thisse, C., and Perrin-Schmitt, F. (1988). Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos. EMBO J. 7, 2175-2183.
57. Tonissen, K. F., Drysdale, T. A., Lints, T. J., Harvey, R. P., and Krieg, P. A. (1994). XNkx2.5: a Xenopus homologue of Nkx-2.5 and tinman. Evidence for a conserved role in cardiac development. Dev. Biol. 162, 325-328.
58. van den Heuvel, M., Nusse, R., Johnston, P., and Lawrence, P. A. (1989). Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication. Cell 59, 739-749.
59. Vincent, J. P., and Lawrence, P. A. (1994). Drosophila wingless sustains engrailed expression only in adjoining cells: evidence from mosaic embryos. Cell 77, 909-915.
60. Woods, D. F., and Bryant, P. J. (1991). The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at separate junctions. Cell 66, 451-464.
61. Wu, X., Golden, K., and Bodmer, R. (1995). Heart development in Drosophila requires the segment polarity gene wingless. Dev. Biol. 169, 619-628.
62. Yanagawa, S., Leeuwen, F., Wodarz, A., Klingensmith, J., and Nusse, R. (1995). The Dishevelled protein is modified by wingless signaling in Drosophila. Genes Dev. 9, 1087-1097.