Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

Nature Genetics

Volumn 15, Issue 1, 1997, Pages 21-29

  Li, Quan Yi ^a   Newbury Ecob, Ruth A ^a   Terrett, Jonathan A ^b   Wilson, David I ^c   Curtis, Andrew R J ^d   Yi, Cheong Ho ^e   Gebühr, Tom ^f   Bullen, Philip J ^g   Robson, Stephen C ^h   Strachan, Tom ^c   Bonnet, Damien ^a   Lyonnet, Stanislas ^a   Young, Ian D ^b   Alexander Raeburn, J ^c   Buckler, Alan J ^d   Law, David J ^e   David Brook, J ^f  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b BRISTOL ROYAL HOSPITAL FOR CHILDREN   (United Kingdom)

^c Royal Hospital for Sick Children ^*

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f HÔPITAL NECKER ENFANTS MALADES   (France)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

^h GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT;

AMINO ACID SEQUENCE; CHROMOSOME 12; DEVELOPMENTAL DISORDER; DNA BINDING; DNA SEQUENCE; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE ISOLATION; GENE MAPPING; GENE MUTATION; GENETIC ANALYSIS; HOLT ORAM SYNDROME; PRIORITY JOURNAL; REVIEW; SEQUENCE ANALYSIS; STOP CODON; TRANSACTIVATION;

ABNORMALITIES, MULTIPLE; AMINO ACID SEQUENCE; ANIMALS; ARM; BASE SEQUENCE; CELL LINE; CHROMOSOMES, ARTIFICIAL, YEAST; CHROMOSOMES, HUMAN, PAIR 12; DNA; DNA-BINDING PROTEINS; EMBRYO; FEMALE; FETAL PROTEINS; GENE EXPRESSION; HEART DEFECTS, CONGENITAL; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PEDIGREE; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SYNDROME; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSLOCATION, GENETIC;

EID: 1842413728     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng0197-21     Document Type: Review

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