A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery

Development

Volumn 133, Issue 7, 2006, Pages 1311-1322

  Elliott, David A ^a,d   Solloway, Mark J ^a,e   Wise, Natalie ^a   Biben, Christine ^a   Costa, Mauro W ^a,c   Furtado, Milena B ^a   Lange, Martin ^a,f   Dunwoodie, Sally ^a,b   Harvey, Richard P ^a,b  

^a VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e GENENTECH INC   (United States)

^f MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

Congenital heart disease; Heart; Homeodomain; Nkx2 5

Indexed keywords

ALANINE; HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.5; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CHIMERA; CONGENITAL HEART DISEASE; CONGENITAL HEART MALFORMATION; DISEASE SEVERITY; DNA BINDING; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; FETUS MORTALITY; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; GENE TARGETING; HEART DEVELOPMENT; IN VITRO STUDY; NEWBORN; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CELL LINE; CELLS, CULTURED; CEPHALOPODA; CONSERVED SEQUENCE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EMBRYO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; GENES, REPORTER; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEINS; HETEROZYGOTE; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION; LUCIFERASES; MICE; MOLECULAR SEQUENCE DATA; MUTATION; MYOCARDIUM; MYOCYTES, CARDIAC; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TYROSINE;

CHIMAERIFORMES;

EID: 33646149991     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.02305     Document Type: Article

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