-
1
-
-
74549140993
-
Prevalence and trends in obesity among US adults, 1999-2008
-
Flegal KM, Carroll MD, Ogden CL, Curtin R (2010) Prevalence and trends in obesity among US adults, 1999-2008. JAMA 303:235-241
-
(2010)
JAMA
, vol.303
, pp. 235-241
-
-
Flegal, K.M.1
Carroll, M.D.2
Ogden, C.L.3
Curtin, R.4
-
3
-
-
0842285784
-
Clinical management of metabolic syndrome: Report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management
-
DOI 10.1161/01.CIR.0000112379.88385.67
-
Grundy SM, Hansen B, Smith SC Jr, Cleeman JI, Kahn RA, American Heart Association (2004) Clinical management of metabolic syndrome report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation 109:551-556 (Pubitemid 38168522)
-
(2004)
Circulation
, vol.109
, Issue.4
, pp. 551-556
-
-
Grundy, S.M.1
Hansen, B.2
Smith Jr., S.C.3
Cleeman, J.I.4
Kahn, R.A.5
-
4
-
-
0032998913
-
Association of plasma lipids and apolipoproteins with the insulin response element in the apoC-III promoter region in familial combined hyperlipidemia
-
Groenendijk M, Cantor RM, Blom NH, Rotter JI, de Bruin TW, Dallinga-Thie GM (1999) Association of plasma lipids and apolipoproteins with the insulin response element in the apoCIII promoter region in familial combined hyperlipidemia. J Lipid Res 40:1036-1044 (Pubitemid 29287874)
-
(1999)
Journal of Lipid Research
, vol.40
, Issue.6
, pp. 1036-1044
-
-
Groenendijk, M.1
Cantor, R.M.2
Blom, N.H.H.C.3
Rotter, J.I.4
De Bruin, T.W.A.5
Dallinga-Thie, G.M.6
-
5
-
-
1442326015
-
Transcriptional control of apolipoprotein A-I gene expression in diabetes
-
DOI 10.2337/diabetes.53.3.513
-
Mooradian AD, Haas MJ, Wong NC (2004) Transcriptional control of apolipoprotein A-I gene expression in diabetes. Diabetes 53:513-520 (Pubitemid 38270617)
-
(2004)
Diabetes
, vol.53
, Issue.3
, pp. 513-520
-
-
Mooradian, A.D.1
Haas, M.J.2
Wong, N.C.W.3
-
6
-
-
0345275811
-
Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects
-
DOI 10.2337/diabetes.52.12.2882
-
Tripathy D, Mohanty P, Dhindsa S, Syed T, Ghanim H, Aljada A, Dandona P (2003) Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. Diabetes 52(12):2882-2887 (Pubitemid 37466856)
-
(2003)
Diabetes
, vol.52
, Issue.12
, pp. 2882-2887
-
-
Tripathy, D.1
Mohanty, P.2
Dhindsa, S.3
Syed, T.4
Ghanim, H.5
Aliada, A.6
Dandona, P.7
-
7
-
-
0030023775
-
The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans
-
Roden M, Perseghin G, Petersen KF, Hwang JH, Cline GW, Gerow K, Rothman DL, Shulman GI (1996) The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans. J Clin Invest 97:642-648 (Pubitemid 26057081)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.3
, pp. 642-648
-
-
Roden, M.1
Perseghin, G.2
Petersen, K.F.3
Hwang, J.-H.4
Cline, G.W.5
Gerow, K.6
Rothman, D.L.7
Shulman, G.I.8
-
8
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI (2000) Cellular mechanisms of insulin resistance. J Clin Invest 106:171-176 (Pubitemid 30483118)
-
(2000)
Journal of Clinical Investigation
, vol.106
, Issue.2
, pp. 171-176
-
-
Shulman, G.I.1
-
9
-
-
33644856005
-
Obesity and the role of adipose tissue in inflammation and metabolism
-
Greenberg AS, Obin MS (2006) Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr 83:S461-S465
-
(2006)
Am J Clin Nutr
, vol.83
-
-
Greenberg, A.S.1
Obin, M.S.2
-
11
-
-
77953835533
-
Intersection between metabolic dysfunction, high fat diet consumption, and brain aging
-
Uranga RM, Bruce-Keller AJ, Morrison CD, Fernandez-Kim SO, Ebenezer PJ, Zhang L, Dasuri K, Keller JN (2010) Intersection between metabolic dysfunction, high fat diet consumption, and brain aging. J Neurochem 114:344-361
-
(2010)
J Neurochem
, vol.114
, pp. 344-361
-
-
Uranga, R.M.1
Bruce-Keller, A.J.2
Morrison, C.D.3
Fernandez-Kim, S.O.4
Ebenezer, P.J.5
Zhang, L.6
Dasuri, K.7
Keller, J.N.8
-
12
-
-
13544253065
-
Metabolic syndrome: A clinical and molecular perspective
-
DOI 10.1146/annurev.med.56.082103.104751
-
Moller DE, Kaufman KD (2005) Metabolic syndrome: a clinical and molecular perspective. Annu Rev Med 56:45-62 (Pubitemid 40299773)
-
(2005)
Annual Review of Medicine
, vol.56
, pp. 45-62
-
-
Moller, D.E.1
Kaufman, K.D.2
-
13
-
-
44649126625
-
Fasting serum free fatty acid composition, waist/hip ratio and insulin activity in essential hypertensive patients
-
DOI 10.1291/hypres.31.623
-
Wang S, Ma A, Song S, Quan Q, Zhao X, Zheng X (2008) Fasting serum free fatty acid composition, waist/hip ratio and insulin activity in essential hypertensive patients. Hypertens Res 31:623-632 (Pubitemid 351772852)
-
(2008)
Hypertension Research
, vol.31
, Issue.4
, pp. 623-632
-
-
Wang, S.1
Ma, A.2
Song, S.3
Quan, Q.4
Zhao, X.5
Zheng, X.6
-
14
-
-
33845914986
-
Mechanisms linking obesity with cardiovascular disease
-
DOI 10.1038/nature05487, PII NATURE05487
-
Van Gaal LF, Mertens IL, De Block CE (2006) Mechanisms linking obesity with cardiovascular disease. Nature 444:875-880 (Pubitemid 46028447)
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 875-880
-
-
Van Gaal, L.F.1
Mertens, I.L.2
De Block, C.E.3
-
15
-
-
21844444790
-
Obesity, insulin resistance, and the metabolic syndrome: Determinants of endothelial dysfunction in whites and blacks
-
DOI 10.1161/CIRCULATIONAHA.104.520130
-
Lteif AA, Han K, Mather KJ (2005) Obesity, insulin resistance, and the metabolic syndrome: determinants of endothelial dysfunction in whites and blacks. Circulation 112:32-38 (Pubitemid 40962566)
-
(2005)
Circulation
, vol.112
, Issue.1
, pp. 32-38
-
-
Lteif, A.A.1
Han, K.2
Mather, K.J.3
-
16
-
-
0029977757
-
Obesity/insulin resistance is associated with endothelial dysfunction: Implications for the syndrome of insulin resistance
-
Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD (1996) Obesity/insulin resistance is associated with endothelial dysfunction: implications for the syndrome of insulin resistance. J Clin Invest 97:2601-2610
-
(1996)
J Clin Invest
, vol.97
, pp. 2601-2610
-
-
Steinberg, H.O.1
Chaker, H.2
Leaming, R.3
Johnson, A.4
Brechtel, G.5
Baron, A.D.6
-
17
-
-
3242662149
-
C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham offspring study
-
DOI 10.1161/01.CIR.0000136581.59584.0E
-
Rutter MK, Meigs JB, Sullivan LM, D'Agostino RB Sr, Wilson PW (2004) C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 110:380-385 (Pubitemid 38993845)
-
(2004)
Circulation
, vol.110
, Issue.4
, pp. 380-385
-
-
Rutter, M.K.1
Meigs, J.B.2
Sullivan, L.M.3
D'Agostino Sr., R.B.4
Wilson, P.W.F.5
-
18
-
-
34548096759
-
Clustering trend of components of metabolic syndrome
-
DOI 10.1016/j.ijcard.2006.08.051, PII S0167527306011326
-
Aizawa Y, Watanabe H, Ramadan MM, Usuda Y, Watanabe T, Sasaki S (2007) Clustering trend of components of metabolic syndrome. Int J Cardiol 121:117-118 (Pubitemid 47287778)
-
(2007)
International Journal of Cardiology
, vol.121
, Issue.1
, pp. 117-118
-
-
Aizawa, Y.1
Watanabe, H.2
Ramadan, M.M.3
Usuda, Y.4
Watanabe, T.5
Sasaki, S.6
-
19
-
-
1842453995
-
Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factor-κB in mononuclear cells
-
DOI 10.1016/j.metabol.2003.10.013
-
Dhindsa S, Tripathy D, Mohanty P, Ghanim H, Syed T, Aljada A, Dandona P (2004) Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factorkappaB in mononuclear cells. Metabolism 53:330-334 (Pubitemid 38684693)
-
(2004)
Metabolism: Clinical and Experimental
, vol.53
, Issue.3
, pp. 330-334
-
-
Dhindsa, S.1
Tripathy, D.2
Mohanty, P.3
Ghanim, H.4
Syed, T.5
Aljada, A.6
Dandona, P.7
-
20
-
-
20344400660
-
Adipocyte signaling and lipid homeostasis: Sequelae of insulin-resistant adipose tissue
-
DOI 10.1161/01.RES.0000165803.47776.38
-
Yu YH, Ginsberg HN (2005) Adipocyte signaling and lipid homeostasis: sequelae of insulin-resistant adipose tissue. Circ Res 96:1042-1052 (Pubitemid 40791376)
-
(2005)
Circulation Research
, vol.96
, Issue.10
, pp. 1042-1052
-
-
Yu, Y.-H.1
Ginsberg, H.N.2
-
21
-
-
2942716780
-
Modern science versus the stigma of obesity
-
DOI 10.1038/nm0604-563
-
Friedman JM (2004) Modern science versus the stigma of obesity. Nat Med 10:563-569 (Pubitemid 38796839)
-
(2004)
Nature Medicine
, vol.10
, Issue.6
, pp. 563-569
-
-
Friedman, J.M.1
-
22
-
-
0033038862
-
Leptin: Fundamental aspects
-
Trayhurn P, Hoggard N, Mercer JG, Rayner DV (1999) Leptin: fundamental aspects. Int J Obes Relat Metab Disord 23(Suppl 1):22-28 (Pubitemid 29101372)
-
(1999)
International Journal of Obesity
, vol.23
, Issue.SUPPL. 1
, pp. 22-28
-
-
Trayhurn, P.1
Hoggard, N.2
Mercer, J.G.3
Rayner, D.V.4
-
23
-
-
0030898516
-
Direct antidiabetic effect of leptin through triglyceride depletion of tissues
-
DOI 10.1073/pnas.94.9.4637
-
Shimabukuro M, Koyama K, Chen G, Wang M-Y, Trieu F, Lee Y, Newgard CB, Unger RH (1997) Direct antidiabetic effect of leptin through triglyceride depletion of tissues. Proc Natl Acad Sci USA 94:4637-4641 (Pubitemid 27194295)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.9
, pp. 4637-4641
-
-
Shimabukuro, M.1
Koyama, K.2
Chen, G.3
Wang, M.-Y.4
Trieu, F.5
Lee, Y.6
Newgard, C.B.7
Unger, R.H.8
-
24
-
-
0032065645
-
What's in a name? In search of leptin's physiologic role
-
DOI 10.1210/jc.83.5.1407
-
Flier JS (1998) What's in a name? In search of leptin's physiologic role. J Clin Endocrinol Metab 83:1407-1413 (Pubitemid 28500994)
-
(1998)
Journal of Clinical Endocrinology and Metabolism
, vol.83
, Issue.5
, pp. 1407-1413
-
-
Flier, J.S.1
-
25
-
-
33745138155
-
Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in diet-induced metabolic syndrome
-
DOI 10.1016/j.metabol.2006.02.022, PII S0026049506000849
-
Roberts CK, Barnard RJ, Sindhu RK, Jurczak M, Ehdaie A, Vaziri ND (2006) Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in dietinduced metabolic syndrome. Metabolism 55:928-934 (Pubitemid 43902895)
-
(2006)
Metabolism: Clinical and Experimental
, vol.55
, Issue.7
, pp. 928-934
-
-
Roberts, C.K.1
Barnard, R.J.2
Sindhu, R.K.3
Jurczak, M.4
Ehdaie, A.5
Vaziri, N.D.6
-
26
-
-
76149111947
-
Inflammatory lipid mediators in adipocyte function and obesity
-
Iyer A, Fairlie DP, Prins JB, Hammock BD, Brown L (2010) Inflammatory lipid mediators in adipocyte function and obesity. Nat Rev Endocrinol 6:71-82
-
(2010)
Nat Rev Endocrinol
, vol.6
, pp. 71-82
-
-
Iyer, A.1
Fairlie, D.P.2
Prins, J.B.3
Hammock, B.D.4
Brown, L.5
-
27
-
-
78650122129
-
Metabolic-cognitive syndrome: A cross-talk between metabolic syndrome and Alzheimer's disease
-
Frisardi V, Solfrizzi V, Seripa D, Capurso C, Santamato A, Sancarlo D, Vendemiale G, Pilotto A, Panza F (2010) Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease. Ageing Res Rev 9:399-417
-
(2010)
Ageing Res Rev
, vol.9
, pp. 399-417
-
-
Frisardi, V.1
Solfrizzi, V.2
Seripa, D.3
Capurso, C.4
Santamato, A.5
Sancarlo, D.6
Vendemiale, G.7
Pilotto, A.8
Panza, F.9
-
28
-
-
77954023854
-
Metabolic syndrome, age-associated neuroendocrine disorders, and dysregulation of tryptophankynurenine metabolism
-
Oxenkrug GF (2010) Metabolic syndrome, age-associated neuroendocrine disorders, and dysregulation of tryptophankynurenine metabolism. Ann N Y Acad Sci 1199:1-14
-
(2010)
Ann N y Acad Sci
, vol.1199
, pp. 1-14
-
-
Oxenkrug, G.F.1
-
29
-
-
67649682161
-
Adiposity, type 2 diabetes, and Alzheimer's disease
-
Luchsinger JA, Gustafson DR (2009) Adiposity, type 2 diabetes, and Alzheimer's disease. J Alzheimers Dis 16:693-704
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 693-704
-
-
Luchsinger, J.A.1
Gustafson, D.R.2
-
30
-
-
77955011739
-
Is insulin resistant brain state a central feature of the metabolic-cognitive syndrome?
-
Frisardi V, Solfrizzi V, Capurso C, Imbimbo BP, Vendemiale G, Seripa D, Pilotto A, Panza F (2010) Is insulin resistant brain state a central feature of the metabolic-cognitive syndrome? J Alzheimers Dis 21:57-63
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 57-63
-
-
Frisardi, V.1
Solfrizzi, V.2
Capurso, C.3
Imbimbo, B.P.4
Vendemiale, G.5
Seripa, D.6
Pilotto, A.7
Panza, F.8
-
31
-
-
35848947008
-
Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: Experimental data
-
Delzenne NM, Cani PD, Neyrinck AM (2007) Modulation of glucagon-like peptide1 and energy metabolism by inulin and oligofructose: experimental data. J Nutr 137(11 Suppl):2547S-2551S (Pubitemid 350058733)
-
(2007)
Journal of Nutrition
, vol.137
, Issue.11
-
-
Delzenne, N.M.1
Cani, P.D.2
Neyrinck, A.M.3
-
32
-
-
35848930359
-
Glucagon-like peptide-1 and energy homeostasis
-
Burcelin R, Cani PD, Knauf C (2007) Glucagon-like peptide-1 and energy homeostasis. J Nutr 137(11 Suppl):2534S-2538S (Pubitemid 350058731)
-
(2007)
Journal of Nutrition
, vol.137
, Issue.11
-
-
Burcelin, R.1
Cani, P.D.2
Knauf, C.3
-
33
-
-
0842324779
-
Obesity Wars: Molecular Progress Confronts an Expanding Epidemic
-
DOI 10.1016/S0092-8674(03)01081-X
-
Flier JS (2004) Obesity wars: molecular progress confronts an expanding epidemic. Cell 116:337-350 (Pubitemid 38167322)
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 337-350
-
-
Flier, J.S.1
-
34
-
-
22744441151
-
Fuel sensing and the central nervous system (CNS): Implications for the regulation of energy balance and the treatment for obesity
-
DOI 10.1111/j.1467-789X.2005.00193.x
-
Seeley RJ, York DA (2005) Fuel sensing and the central nervous system (CNS): implications for the regulation of energy balance and the treatment for obesity. Obes Rev 6:259-265 (Pubitemid 41032801)
-
(2005)
Obesity Reviews
, vol.6
, Issue.3
, pp. 259-265
-
-
Seeley, R.J.1
York, D.A.2
-
35
-
-
11144338712
-
Gastrointestinal hormones and food intake
-
DOI 10.1053/j.gastro.2004.10.043, PII S0016508504019936
-
Strader AD, Woods SC (2005) Gastrointestinal hormones and food intake. Gastroenterology 128(1):175-191 (Pubitemid 40039969)
-
(2005)
Gastroenterology
, vol.128
, Issue.1
, pp. 175-191
-
-
Strader, A.D.1
Woods, S.C.2
-
36
-
-
32644439916
-
The brain and the metabolic syndrome: Not a wireless connection
-
DOI 10.1210/en.2005-1586
-
Perez-Tilve D, Stern JE, Tschöp M (2006) The brain and the metabolic syndrome: not a wireless connection. Endocrinology 147:1136-1139 (Pubitemid 43244344)
-
(2006)
Endocrinology
, vol.147
, Issue.3
, pp. 1136-1139
-
-
Perez-Tilve, D.1
Stern, J.E.2
Tschop, M.3
-
37
-
-
64249103514
-
Plasticity of central autonomic neural circuits in diabetes
-
Zsombok A, Smith BN (2009) Plasticity of central autonomic neural circuits in diabetes. Biochim Biophys Acta 1792:423-431
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 423-431
-
-
Zsombok, A.1
Smith, B.N.2
-
38
-
-
16244383657
-
A brain-liver circuit regulates glucose homeostasis
-
DOI 10.1016/j.cmet.2004.11.001, PII S1550413104000026
-
Pocai A, Obici S, Schwartz GJ, Rossetti L (2005) A brain-liver circuit regulates glucose homeostasis. Cell Metab 1:53-61 (Pubitemid 43960581)
-
(2005)
Cell Metabolism
, vol.1
, Issue.1
, pp. 53-61
-
-
Pocai, A.1
Obici, S.2
Schwartz, G.J.3
Rossetti, L.4
-
39
-
-
27144523482
-
Melanocortin-4 receptor mRNA is expressed in sympathetic nervous system outflow neurons to white adipose tissue
-
DOI 10.1152/ajpregu.00348.2005 58-5
-
Song CK, Jackson RM, Harris RB, Richard D, Bartness TJ (2005) Melanocortin-4 receptor mRNA is expressed in sympathetic nervous system outflow neurons to white adipose tissue. Am J Physiol Regul Integr Comp Physiol 289:R1467-R1476 (Pubitemid 41507413)
-
(2005)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.289
, Issue.5
-
-
Song, C.K.1
Jackson, R.M.2
Harris, R.B.S.3
Richard, D.4
Bartness, T.J.5
-
40
-
-
33746189654
-
Brain glucose sensing: A subtle mechanism
-
DOI 10.1097/01.mco.0000232908.84483.e0, PII 0007519720060700000019
-
Penicaud L, Leloup C, Fioramonti X, Lorsignol A, Benani A (2006) Brain glucose sensing: a subtle mechanism. Curr Opin Clin Nutr Metab Care 9:458-462 (Pubitemid 44097818)
-
(2006)
Current Opinion in Clinical Nutrition and Metabolic Care
, vol.9
, Issue.4
, pp. 458-462
-
-
Penicaud, L.1
Leloup, C.2
Fioramonti, X.3
Lorsignol, A.4
Benani, A.5
-
42
-
-
0021891128
-
Blood glucose levels modulate efferent activity in the vagal supply to the rat liver
-
Niijima A (1985) Blood glucose levels modulate efferent activity in the vagal supply to the rat liver. J Physiol 364:105-112 (Pubitemid 15067202)
-
(1985)
Journal of Physiology
, vol.364
, pp. 105-112
-
-
Niijima, A.1
-
43
-
-
0014012147
-
Reciprocal influences of the ventromedial and lateral hypothalamic nuclei on blood glucose level and liver glycogen content
-
Shimazu T, Fukuda A, Ban T (1966) Reciprocal influences of the ventromedial and lateral hypothalamic nuclei on blood glucose level and liver glycogen content. Nature 210:1178-1179
-
(1966)
Nature
, vol.210
, pp. 1178-1179
-
-
Shimazu, T.1
Fukuda, A.2
Ban, T.3
-
44
-
-
17844379717
-
ATP channels control hepatic glucose production
-
DOI 10.1038/nature03439
-
Pocai A, Lam TK, Gutierrez-Juarez R, Obici S, Schwartz GJ, Bryan J, Aguilar-Bryan L, Rossetti L (2005) Hypothalamic K(ATP) channels control hepatic glucose production. Nature 434:1026-1031 (Pubitemid 40586051)
-
(2005)
Nature
, vol.434
, Issue.7036
, pp. 1026-1031
-
-
Pocal, A.1
Lam, T.K.T.2
Gutierrez-Juarez, R.3
Obici, S.4
Schwartz, G.J.5
Bryan, J.6
Aguilar-Bryan, L.7
Rossetti, L.8
-
45
-
-
0022510796
-
Autoradiographic localization of insulin receptors in rat brain: Prominence in olfactory and limbic areas
-
DOI 10.1016/0306-4522(86)90082-5
-
Hill JM, Lesniak MA, Pert CB, Roth J (1986) Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas. Neuroscience 17:1127-1138 (Pubitemid 16080101)
-
(1986)
Neuroscience
, vol.17
, Issue.4
, pp. 1127-1138
-
-
Hill, J.M.1
Lesniak, M.A.2
Pert, C.B.3
Roth, J.4
-
46
-
-
68949089312
-
Alzheimer's disease is type 3 diabetes-evidence reviewed
-
de la Monte SM, Wands JR (2008) Alzheimer's disease is type 3 diabetes-evidence reviewed. J Diabetes Sci Technol 2:1101-1113
-
(2008)
J Diabetes Sci Technol
, vol.2
, pp. 1101-1113
-
-
De La Monte, S.M.1
Wands, J.R.2
-
47
-
-
54349085910
-
IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination
-
Freude S, Leeser U, Muller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Kohler C, Schroder H, Krone W, Bruning JC, Schubert M (2008) IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination. J Neurochem 107:907-917
-
(2008)
J Neurochem
, vol.107
, pp. 907-917
-
-
Freude, S.1
Leeser, U.2
Muller, M.3
Hettich, M.M.4
Udelhoven, M.5
Schilbach, K.6
Tobe, K.7
Kadowaki, T.8
Kohler, C.9
Schroder, H.10
Krone, W.11
Bruning, J.C.12
Schubert, M.13
-
48
-
-
0030330547
-
The role of the insulin-like growth factors in the central nervous system
-
D'Ercole AJ, Ye P, Calikoglu AS, Gutierrez-Ospina G (1996) The role of the insulin-like growth factors in the central nervous system. Mol Neurobiol 13:227-255 (Pubitemid 126715878)
-
(1996)
Molecular Neurobiology
, vol.13
, Issue.3
, pp. 227-255
-
-
D'Ercole, A.J.1
Ye, P.2
Calikoglu, A.S.3
Gutierrez-Ospina, G.4
-
49
-
-
15044350668
-
The expanding TOR signaling network
-
DOI 10.1016/j.ceb.2005.02.008, Cell Regulation
-
Martin DE, Hall MN (2005) The expanding TOR signaling network. Curr Opin Cell Biol 17(2):158-166 (Pubitemid 40380939)
-
(2005)
Current Opinion in Cell Biology
, vol.17
, Issue.2
, pp. 158-166
-
-
Martin, D.E.1
Hall, M.N.2
-
50
-
-
33846841155
-
A link between protein translation and body weight
-
DOI 10.1172/JCI31289
-
Rui L (2007) A link between protein translation and body weight. J Clin Invest 117:310-313 (Pubitemid 46203959)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.2
, pp. 310-313
-
-
Rui, L.1
-
51
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
DOI 10.1038/ncb1183
-
Jacinto E, Loewith R, Schmidt A, Lin S, Ruegg MA, Hall A, Hall MN (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 6:1122-1128 (Pubitemid 39468014)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.11
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
Hall, M.N.7
-
52
-
-
42449104351
-
MTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes
-
Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N, Leibowitz G (2008) mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. Diabetes 57:945-957
-
(2008)
Diabetes
, vol.57
, pp. 945-957
-
-
Fraenkel, M.1
Ketzinel-Gilad, M.2
Ariav, Y.3
Pappo, O.4
Karaca, M.5
Castel, J.6
Berthault, M.F.7
Magnan, C.8
Cerasi, E.9
Kaiser, N.10
Leibowitz, G.11
-
53
-
-
0033436355
-
Insulin and leptin: Dual adiposity signals to the brain for the regulation of food intake and body weight
-
DOI 10.1016/S0006-8993(99)01974-5, PII S0006899399019745
-
Baskin DG, Figlewicz Lattermann D, Seeley RJ, Woods SC, Porte D Jr, Schwartz MW (1999) Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. Brain Res 848:114-123 (Pubitemid 30001660)
-
(1999)
Brain Research
, vol.848
, Issue.1-2
, pp. 114-123
-
-
Baskin, D.G.1
Figlewicz Lattemann, D.2
Seeley, R.J.3
Woods, S.C.4
Porte Jr., D.5
Schwartz, M.W.6
-
54
-
-
0026668877
-
Insulin and insulinomimetic agents induce activation of phosphatidylinositol 30-kinase upon its association with pp185 (IRS-1) in intact rat livers
-
Hadari YR, Tzahar E, Nadiv O, Rothenberg P, Roberts CT Jr, LeRoith D, Yarden Y, Zick Y (1992) Insulin and insulinomimetic agents induce activation of phosphatidylinositol 30-kinase upon its association with pp185 (IRS-1) in intact rat livers. J Biol Chem 267:17483-17486
-
(1992)
J Biol Chem
, vol.267
, pp. 17483-17486
-
-
Hadari, Y.R.1
Tzahar, E.2
Nadiv, O.3
Rothenberg, P.4
Roberts Jr., C.T.5
Leroith, D.6
Yarden, Y.7
Zick, Y.8
-
56
-
-
0025765803
-
SH2 and SH3 Domains: Elements that control interactions of cytoplasmic signaling proteins
-
Koch CA, Anderson D, Moran MF, Ellis C, Pawson T (1991) SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science 252:668-674 (Pubitemid 21916987)
-
(1991)
Science
, vol.252
, Issue.5006
, pp. 668-674
-
-
Koch, C.A.1
Anderson, D.2
Moran, M.F.3
Ellis, C.4
Pawson, T.5
-
58
-
-
2342444310
-
Leptin receptor signaling and the regulation of mammalian physiology
-
Myers MG Jr (2004) Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog Horm Res 59:287-304
-
(2004)
Recent Prog Horm Res
, vol.59
, pp. 287-304
-
-
Myers Jr., M.G.1
-
59
-
-
16844369740
-
PI3K integrates the action of insulin and leptin on hypothalamic neurons
-
DOI 10.1172/JCI200524301
-
Xu AW, Kaelin CB, Takeda K, Akira S, Schwartz MW, Barsh GS (2005) PI3K integrates the action of insulin and leptin on hypothalamic neurons. J Clin Invest 115:951-958 (Pubitemid 40489399)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.4
, pp. 951-958
-
-
Xu, A.W.1
Kaelin, C.B.2
Takeda, K.3
Akira, S.4
Schwartz, M.W.5
Barsh, G.S.6
-
60
-
-
33644665508
-
Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling
-
DOI 10.1152/ajpendo.00094.2005
-
Morrison CD, Morton GJ, Niswender KD, Gelling RW, Schwartz MW (2005) Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling. Am J Physiol Endocrinol Metab 289:E1051-E1057 (Pubitemid 43772054)
-
(2005)
American Journal of Physiology - Endocrinology and Metabolism
, vol.289
, Issue.6
-
-
Morrison, C.D.1
Morton, G.J.2
Niswender, K.D.3
Gelling, R.W.4
Schwartz, M.W.5
-
61
-
-
12944261926
-
Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation
-
Mirshamsi S, Laidlaw HA, Ning K, Anderson E, Burgess LA, Gray A, Sutherland C, Ashford ML (2004) Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation. BMC Neurosci 5:54
-
(2004)
BMC Neurosci
, vol.5
, pp. 54
-
-
Mirshamsi, S.1
Laidlaw, H.A.2
Ning, K.3
Anderson, E.4
Burgess, L.A.5
Gray, A.6
Sutherland, C.7
Ashford, M.L.8
-
62
-
-
33745576798
-
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
-
DOI 10.1038/nn1731, PII N1731
-
Kim MS, Pak YK, Jang PG, Namkoong C, Choi YS, Won JC, Kim KS, Kim SW, Kim HS, Park JY, Kim YB, Lee KU (2006) Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis. Nat Neurosci 9:901-906 (Pubitemid 43980504)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.7
, pp. 901-906
-
-
Kim, M.-S.1
Pak, Y.K.2
Jang, P.-G.3
Namkoong, C.4
Choi, Y.-S.5
Won, J.-C.6
Kim, K.-S.7
Kim, S.-W.8
Kim, H.-S.9
Park, J.-Y.10
Kim, Y.-B.11
Lee, K.-U.12
-
63
-
-
67650088267
-
The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling
-
Morton GJ, Blevins JE, Kim F, Matsen M, Figlewicz DP (2009) The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling. Am J Physiol Endocrinol Metab 297:E202-E210
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
-
-
Morton, G.J.1
Blevins, J.E.2
Kim, F.3
Matsen, M.4
Figlewicz, D.P.5
-
65
-
-
4243098381
-
Dietary fat, insulin sensitivity and the metabolic syndrome
-
DOI 10.1016/j.clnu.2004.02.006, PII S0261561404000263
-
Riccardi G, Giacco R, Rivellese AA (2004) Dietary fat, insulin sensitivity and the metabolic syndrome. Clin Nutr 23:447-456 (Pubitemid 39107022)
-
(2004)
Clinical Nutrition
, vol.23
, Issue.4
, pp. 447-456
-
-
Riccardi, G.1
Giacco, R.2
Rivellese, A.A.3
-
66
-
-
0023240831
-
Fish oil prevents insulin resistance induced by high-fat feeding in rats
-
Storlien LH, Kraegen EW, Chisholm DJ, Ford GL, Bruce DG, Pascoe WS (1987) Fish oil prevents insulin resistance induced by high-fat feeding in rats. Science 237:885-888 (Pubitemid 17128276)
-
(1987)
Science
, vol.237
, Issue.4817
, pp. 885-888
-
-
Storlien, L.H.1
Kraegen, E.W.2
Chisholm, D.J.3
-
67
-
-
34250326302
-
The emerging role of FOXO transcription factors in pancreatic beta cells
-
Glauser DA, Schlegel W (2007) The emerging role of FOXO transcription factors in pancreatic beta cells. J Endocrinol 193:195-207
-
(2007)
J Endocrinol
, vol.193
, pp. 195-207
-
-
Glauser, D.A.1
Schlegel, W.2
-
68
-
-
0036950665
-
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth
-
DOI 10.1172/JCI200216857
-
Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH 3rd, Wright CV, White MF, Arden KC, Accili D (2002) The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J Clin Invest 110:1839-1847 (Pubitemid 36076491)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.12
, pp. 1839-1847
-
-
Kitamura, T.1
Nakae, J.2
Kitamura, Y.3
Kido, Y.4
Biggs III, W.H.5
Wright, C.V.E.6
White, M.F.7
Arden, K.C.8
Accili, D.9
-
71
-
-
0037959071
-
The state of lipid rafts: From model membranes to cells
-
DOI 10.1146/annurev.biophys.32.110601.142439
-
Edidin M (2003) The state of lipid rafts: from model membranes to cells. Annu Rev Biophys Biomol Struct 32:257-283 (Pubitemid 37056230)
-
(2003)
Annual Review of Biophysics and Biomolecular Structure
, vol.32
, pp. 257-283
-
-
Edidin, M.1
-
72
-
-
76749104269
-
The nutritional and clinical significance of lipid rafts
-
Yaqoob P, Shaikh SR (2010) The nutritional and clinical significance of lipid rafts. Curr Opin Clin Nutr Metab Care 13:156-166
-
(2010)
Curr Opin Clin Nutr Metab Care
, vol.13
, pp. 156-166
-
-
Yaqoob, P.1
Shaikh, S.R.2
-
73
-
-
0025755283
-
Insulin in the cerebrospinal fluid
-
Plata-Salaman CR (1991) Insulin in the cerebrospinal fluid. Neurosci Biobehav Rev 15:243-258
-
(1991)
Neurosci Biobehav Rev
, vol.15
, pp. 243-258
-
-
Plata-Salaman, C.R.1
-
74
-
-
0024345665
-
Distribution of insulin receptor-like immunoreactivity in the rat forebrain
-
DOI 10.1016/0306-4522(89)90036-5
-
Unger J, McNeill TH, Moxley RT, White M, Moss A, Livingston JN (1989) Distribution of insulin receptor-like immunoreactivity in the rat forebrain. Neuroscience 31:143-157 (Pubitemid 19209704)
-
(1989)
Neuroscience
, vol.31
, Issue.1
, pp. 143-157
-
-
Unger, J.1
McNeill, T.H.2
Moxley III, R.T.3
White, M.4
Moss, A.5
Livingston, J.N.6
-
75
-
-
15244350991
-
Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease
-
de la Monte SM, Wands JR (2005) Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J Alzheimers Dis 7:45-61 (Pubitemid 40387184)
-
(2005)
Journal of Alzheimer's Disease
, vol.7
, Issue.1
, pp. 45-61
-
-
De La Monte, S.M.1
Wands, J.R.2
-
76
-
-
78650647440
-
Nutraceutical properties of Mediterranean diet and cognitive decline: Possible underlying mechanisms
-
Frisardi V, Panza F, Seripa D, Imbimbo BP, Vendemiale G, Pilotto A, Solfrizzi V (2010) Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms. J Alzheimers Dis 22:715-740
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 715-740
-
-
Frisardi, V.1
Panza, F.2
Seripa, D.3
Imbimbo, B.P.4
Vendemiale, G.5
Pilotto, A.6
Solfrizzi, V.7
-
78
-
-
10744222995
-
Oxidative stress is associated with adiposity and insulin resistance in men
-
DOI 10.1210/jc.2003-030202
-
Urakawa H, Katsuki A, Sumida Y, Gabazza EC, Murashima S, Morioka K, Maruyama N, Kitagawa N, Tanaka T, Hori Y, Nakatani K, Yano Y, Adachi Y (2003) Oxidative stress is associated with adiposity and insulin resistance in men. J Clin Endocrinol Metab 88:4673-4676 (Pubitemid 37357510)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.10
, pp. 4673-4676
-
-
Urakawa, H.1
Katsuki, A.2
Sumida, Y.3
Gabazza, E.C.4
Murashima, S.5
Morioka, K.6
Maruyama, N.7
Kitagawa, N.8
Tanaka, T.9
Hori, Y.10
Nakatani, K.11
Yano, Y.12
Adachi, Y.13
-
79
-
-
31344447948
-
The metabolic syndrome: Inflammation, diabetes mellitus, and cardiovascular disease
-
DOI 10.1016/j.amjcard.2005.11.010, PII S000291490502028X
-
Haffner SM (2006) The metabolic syndrome: inflammation, diabetes mellitus, and cardiovascular disease. Am J Cardiol 97:3A-11A (Pubitemid 43139714)
-
(2006)
American Journal of Cardiology
, vol.97
, Issue.2 SUPPL. 1
-
-
Haffner, S.M.1
-
80
-
-
0036796875
-
Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
-
DOI 10.1210/er.2001-0039
-
Evans JL, Goldfine ID, Maddux BA, Grodsky GM (2002) Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 23:599-622 (Pubitemid 35191625)
-
(2002)
Endocrine Reviews
, vol.23
, Issue.5
, pp. 599-622
-
-
Evans, J.L.1
Goldfine, I.D.2
Maddux, B.A.3
Grodsky, G.M.4
-
81
-
-
33746377553
-
Obesity-related derangements in metabolic regulation
-
DOI 10.1146/annurev.biochem.75.103004.142512
-
Muoio DM, Newgard CB (2006) Obesity-related derangements in metabolic regulation. Annu Rev Biochem 75:367-401 (Pubitemid 44118037)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 367-401
-
-
Muoio, D.M.1
Newgard, C.B.2
-
82
-
-
33750572410
-
Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells
-
DOI 10.1042/BJ20060244
-
Dimopoulos N, Watson M, Sakamoto K, Hundal HS (2006) Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells. Biochem J 399:473-481 (Pubitemid 44672638)
-
(2006)
Biochemical Journal
, vol.399
, Issue.3
, pp. 473-481
-
-
Dimopoulos, N.1
Watson, M.2
Sakamoto, K.3
Hundal, H.S.4
-
83
-
-
0035896366
-
Protein kinase B (PKB/Akt) - A key regulator of glucose transport?
-
DOI 10.1016/S0014-5793(01)02242-6, PII S0014579301022426
-
Hajduch E, Litherland GJ, Hundal HS (2001) Protein kinase B: a key regulator of glucose transport? FEBS Lett 492:199-203 (Pubitemid 32217828)
-
(2001)
FEBS Letters
, vol.492
, Issue.3
, pp. 199-203
-
-
Hajduch, E.1
Litherland, G.J.2
Hundal, H.S.3
-
84
-
-
0037135536
-
De novo sphingolipid biosynthesis: A necessary, but dangerous, pathway
-
DOI 10.1074/jbc.R200009200
-
Merrill AH Jr (2002) De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway. J Biol Chem 277:25843-25846 (Pubitemid 34967059)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.29
, pp. 25843-25846
-
-
Merrill Jr., A.H.1
-
85
-
-
33847332202
-
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
-
Holland WL, Brozinick JT, Wang LP, Hawkins ED, Sargent KM, Liu Y, Narra K, Hoehn KL, Knotts TA, Siesky A, Nelson DH, Karathanasis SK, Fontenot GK, Birnbaum MJ, Summers SA (2007) Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance. Cell Metab 593:167-179
-
(2007)
Cell Metab
, vol.593
, pp. 167-179
-
-
Holland, W.L.1
Brozinick, J.T.2
Wang, L.P.3
Hawkins, E.D.4
Sargent, K.M.5
Liu, Y.6
Narra, K.7
Hoehn, K.L.8
Knotts, T.A.9
Siesky, A.10
Nelson, D.H.11
Karathanasis, S.K.12
Fontenot, G.K.13
Birnbaum, M.J.14
Summers, S.A.15
-
86
-
-
0028348472
-
Effect of fatty acids on insulin release: Role of chain length and degree of unsaturation
-
Opara EC, Garfinkel M, Hubbard VS, Burch WM, Akwari OE (1994) Effect of fatty acids on insulin release: role of chain length and degree of unsaturation. Am J Physiol 266(4 Pt 1):E635-E639
-
(1994)
Am J Physiol
, vol.266
, Issue.4 PART 1
-
-
Opara, E.C.1
Garfinkel, M.2
Hubbard, V.S.3
Burch, W.M.4
Akwari, O.E.5
-
87
-
-
0034982345
-
Dietary fat intake and risk of type 2 diabetes in women
-
Salmeron J, Hu FB, Manson JE, Stampfer MJ, Colditz GA, Rimm EB, Willett WC (2001) Dietary fat intake and risk of type 2 diabetes in women. Am J Clin Nutr 73:1019-1026 (Pubitemid 32496939)
-
(2001)
American Journal of Clinical Nutrition
, vol.73
, Issue.6
, pp. 1019-1026
-
-
Salmeron, J.1
Hu, F.B.2
Manson, J.E.3
Stampfer, M.J.4
Colditz, G.A.5
Rimm, E.B.6
Willett, W.C.7
-
88
-
-
61949365497
-
Prevention of insulin resistance by n-3 polyunsaturated fatty acids
-
Fedor D, Kelley DS (2009) Prevention of insulin resistance by n-3 polyunsaturated fatty acids. Curr Opin Clin Nutr Metab Care 12:138-146
-
(2009)
Curr Opin Clin Nutr Metab Care
, vol.12
, pp. 138-146
-
-
Fedor, D.1
Kelley, D.S.2
-
89
-
-
19344368463
-
Eicosapentaenoic fatty acid increases leptin secretion from primary cultured rat adipocytes: Role of glucose metabolism
-
DOI 10.1152/ajpregu.00727.2004 57-6
-
Pérez-Matute P, Marti A, Martínez JA, Fernández- Otero MP, Stanhope KL, Havel PJ, Moreno-Aliaga MJ (2005) Eicosapentaenoic fatty acid increases leptin secretion from primary cultured rat adipocytes: role of glucose metabolism. Am J Physiol Regul Integr Comp Physiol 288:R1682-R1688 (Pubitemid 40720718)
-
(2005)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.288
, Issue.6
-
-
Perez-Matute, P.1
Marti, A.2
Martinez, J.A.3
Fernandez-Otero, M.P.4
Stanhope, K.L.5
Havel, P.J.6
Moreno-Aliaga, M.J.7
-
90
-
-
78149275191
-
Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation
-
Kalupahana NS, Claycombe K, Newman SJ, Stewart T, Siriwardhana N, Matthan N, Lichtenstein AH, Moustaid-Moussa N (2010) Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation. J Nutr 140:1915-1922
-
(2010)
J Nutr
, vol.140
, pp. 1915-1922
-
-
Kalupahana, N.S.1
Claycombe, K.2
Newman, S.J.3
Stewart, T.4
Siriwardhana, N.5
Matthan, N.6
Lichtenstein, A.H.7
Moustaid-Moussa, N.8
-
91
-
-
34447115107
-
Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells
-
DOI 10.1074/jbc.M700647200
-
Kraveka JM, Li L, Szulc ZM, Bielawski J, Ogretmen B, Hannun YA, Obeid LM, Bielawska A (2007) Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells. J Biol Chem 282:16718-16728 (Pubitemid 47093220)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.23
, pp. 16718-16728
-
-
Kraveka, J.M.1
Li, L.2
Szulc, Z.M.3
Bielawski, J.4
Ogretmen, B.5
Hannun, Y.A.6
Obeid, L.M.7
Bielawska, A.8
-
92
-
-
84857041633
-
Differential regulation of dihydroceramide desaturase by palmitate vs. monounsaturated fatty acids: Implications to insulin resistance
-
Hu W, Ross JS, Geng T, Brice SE, Cowart LA (2011) Differential regulation of dihydroceramide desaturase by palmitate vs. monounsaturated fatty acids: implications to insulin resistance. J Biol Chem 285:35792-35802
-
(2011)
J Biol Chem
, vol.285
, pp. 35792-35802
-
-
Hu, W.1
Ross, J.S.2
Geng, T.3
Brice, S.E.4
Cowart, L.A.5
-
93
-
-
0027437753
-
Diacylglycerol/protein kinase C signalling: A mechanism for insulin resistance?
-
Shmueli E, Alberti KG, Record CO (1993) Diacylglycerol/protein kinase C signalling: a mechanism for insulin resistance? J Intern Med 234:397-400 (Pubitemid 23305788)
-
(1993)
Journal of Internal Medicine
, vol.234
, Issue.4
, pp. 397-400
-
-
Shmueli, E.1
Alberti, K.G.M.M.2
Record, C.O.3
-
94
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α
-
Itani SI, Ruderman NB, Schmieder F, Boden G (2002) Lipidinduced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes 51:2005-2011 (Pubitemid 34729001)
-
(2002)
Diabetes
, vol.51
, Issue.7
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
Boden, G.4
-
95
-
-
0035018260
-
DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells
-
Montell E, Turini M, Marotta M, Roberts M, Noé V, Ciudad CJ, Macé K, Gómez-Foix AM (2001) DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells. Am J Physiol Endocrinol Metab 280:E229-E237
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Montell, E.1
Turini, M.2
Marotta, M.3
Roberts, M.4
Noé, V.5
Ciudad, C.J.6
MacÉ, K.7
Gómez-Foix, A.M.8
-
96
-
-
0035149738
-
Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats
-
Dobbins RL, Szczepaniak LS, Bentley B, Esser V, Myhill J, McGarry JD (2001) Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats. Diabetes 50:123-130 (Pubitemid 32047990)
-
(2001)
Diabetes
, vol.50
, Issue.1
, pp. 123-130
-
-
Dobbins, R.L.1
Szczepaniak, L.S.2
Bentley, B.3
Esser, V.4
Myhill, J.5
Denis McGarry, J.6
-
97
-
-
77957569202
-
Targeting ceramide synthesis to reverse insulin resistance
-
Schmitz-Peiffer C (2010) Targeting ceramide synthesis to reverse insulin resistance. Diabetes 59:2351-2353
-
(2010)
Diabetes
, vol.59
, pp. 2351-2353
-
-
Schmitz-Peiffer, C.1
-
98
-
-
3042540864
-
Physiological actions of diacylglycerol outcome
-
DOI 10.1097/00075197-200403000-00007
-
Tada N (2004) Physiological actions of diacylglycerol outcome. Curr Opin Clin Nutr Metab Care 7:145-149 (Pubitemid 40340676)
-
(2004)
Current Opinion in Clinical Nutrition and Metabolic Care
, vol.7
, Issue.2
, pp. 145-149
-
-
Tada, N.1
-
99
-
-
34248657542
-
A 1,3-diacylglycerol-rich oil induces less atherosclerosis and lowers plasma cholesterol in diabetic apoE-deficient mice
-
DOI 10.1016/j.atherosclerosis.2006.08.024, PII S0021915006004825
-
Fujii A, Allen TJ, Nestel PJ (2007) A 1, 3-diacylglycerol-rich oil induces less atherosclerosis and lowers plasma cholesterol in diabetic apoE-deficient mice. Atherosclerosis 193:55-61 (Pubitemid 46776710)
-
(2007)
Atherosclerosis
, vol.193
, Issue.1
, pp. 55-61
-
-
Fujii, A.1
Allen, T.J.2
Nestel, P.J.3
-
100
-
-
33745154502
-
Effect of diacylglycerol on the development of impaired glucose tolerance in sucrose-fed rats
-
DOI 10.1007/s11745-006-5105-7
-
Meguro S, Osaki N, Matsuo N, Tokimitsu I (2006) Effect of diacylglycerol on the development of impaired glucose tolerance in sucrose-fed rats. Lipids 41:347-355 (Pubitemid 43902263)
-
(2006)
Lipids
, vol.41
, Issue.4
, pp. 347-355
-
-
Meguro, S.1
Osaki, N.2
Matsuo, N.3
Tokimitsu, I.4
-
101
-
-
0036669924
-
Anti-obesity effect of dietary diacylglycerol in C57BL/6J mice: Dietary diacylglycerol stimulates intestinal lipid metabolism
-
Murase T, Aoki M, Wakisaka T, Hase T, Tokimitsu I (2002) Anti-obesity effect of dietary diacylglycerol in C57BL/6J mice: dietary diacylglycerol stimulates intestinal lipid metabolism. J Lipid Res 43:1312-1319 (Pubitemid 34993532)
-
(2002)
Journal of Lipid Research
, vol.43
, Issue.8
, pp. 1312-1319
-
-
Murase, T.1
Aoki, M.2
Wakisaka, T.3
Hase, T.4
Tokimitsu, I.5
-
102
-
-
38949210746
-
Diacylglycerol oil for the metabolic syndrome
-
Yanai H, Tomono Y, Ito K, Furutani N, Yoshida H, Tada N (2007) Diacylglycerol oil for the metabolic syndrome. Nutr J 6:43-45
-
(2007)
Nutr J
, vol.6
, pp. 43-45
-
-
Yanai, H.1
Tomono, Y.2
Ito, K.3
Furutani, N.4
Yoshida, H.5
Tada, N.6
-
103
-
-
45149106053
-
Sphingolipids, insulin resistance, and metabolic disease: New insights from in vivo manipulation of sphingolipid metabolism
-
DOI 10.1210/er.2007-0025
-
Holland WL, Summers SA (2008) Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism. Endocr Rev 29:381-402 (Pubitemid 351831506)
-
(2008)
Endocrine Reviews
, vol.29
, Issue.4
, pp. 381-402
-
-
Holland, W.L.1
Summers, S.A.2
-
104
-
-
42249105215
-
The sphingolipid salvage pathway in ceramide metabolism and signaling
-
Kitatani K, Idkowiak-Baldys J, Hannun YA (2008) The sphingolipid salvage pathway in ceramide metabolism and signaling. Cell Signal 20:1010-1018
-
(2008)
Cell Signal
, vol.20
, pp. 1010-1018
-
-
Kitatani, K.1
Idkowiak-Baldys, J.2
Hannun, Y.A.3
-
105
-
-
0038532298
-
A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
-
DOI 10.1074/jbc.M212307200
-
Chavez JA, Knotts TA, Wang LP, Li G, Dobrowsky RT, Florant GL, Summers SA (2003) A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J Biol Chem 278:10297-10303 (Pubitemid 36800291)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.12
, pp. 10297-10303
-
-
Chavez, J.A.1
Knotts, T.A.2
Wang, L.-P.3
Li, G.4
Dobrowsky, R.T.5
Florant, G.L.6
Summers, S.A.7
-
106
-
-
31644443192
-
Ceramides in insulin resistance and lipotoxicity
-
DOI 10.1016/j.plipres.2005.11.002, PII S0163782705000500
-
Summers SA (2006) Ceramides in insulin resistance and lipotoxicity. Prog Lipid Res 45:42-72 (Pubitemid 43170804)
-
(2006)
Progress in Lipid Research
, vol.45
, Issue.1
, pp. 42-72
-
-
Summers, S.A.1
-
107
-
-
1442314865
-
Effect of streptozotocin-diabetes on the functioning of the sphingomyelin-signalling pathway in skeletal muscles of the rat
-
DOI 10.1055/s-2004-814197
-
Gorska M, Dobrzyn A, Zendzian-Piotrowska M, Gorski J (2004) Effect of streptozotocin-diabetes on the functioning of the sphingomyelin-signalling pathway in skeletal muscles of the rat. Horm Metab Res 36:14-21 (Pubitemid 38283188)
-
(2004)
Hormone and Metabolic Research
, vol.36
, Issue.1
, pp. 14-21
-
-
Gorska, M.1
Dobrzyn, A.2
Zendzian-Piotrowska, M.3
Gorski, J.4
-
108
-
-
0346729968
-
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
-
DOI 10.2337/diabetes.53.1.25
-
Adams JM 2nd, Pratipanawatr T, Berria R, Wang E, DeFronzo RA, Sullards MC, Mandarino LJ (2004) Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 53:25-31 (Pubitemid 38044694)
-
(2004)
Diabetes
, vol.53
, Issue.1
, pp. 25-31
-
-
Adams II, J.M.1
Pratipanawatr, T.2
Berria, R.3
Wang, E.4
DeFronzo, R.A.5
Sullards, M.C.6
Mandarino, L.J.7
-
109
-
-
0142091454
-
Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism
-
DOI 10.1128/MCB.23.21.7794-7808.2003
-
Powell DJ, Hajduch E, Kular G, Hundal HS (2003) Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol Cell Biol 23:7794-7808 (Pubitemid 37271476)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.21
, pp. 7794-7808
-
-
Powell, D.J.1
Hajduch, E.2
Kular, G.3
Hundal, H.S.4
-
110
-
-
0031841949
-
Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide
-
Summers SA, Garza LA, Zhou H, Birnbaum MJ (1998) Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide. Mol Cell Biol 18:5457-5464 (Pubitemid 28388128)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.9
, pp. 5457-5464
-
-
Summers, S.A.1
Garza, L.A.2
Zhou, H.3
Birnbaum, M.J.4
-
111
-
-
0036154215
-
Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes
-
DOI 10.1016/S0898-6568(01)00238-8, PII S0898656801002388
-
Resjo S, Goransson O, Harndahl L, Zolnierowicz S, Manganiello V, Degerman E (2002) Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes. Cell Signal 14:231-238 (Pubitemid 34102452)
-
(2002)
Cellular Signalling
, vol.14
, Issue.3
, pp. 231-238
-
-
Resjo, S.1
Goransson, O.2
Harndahl, L.3
Zolnierowicz, S.4
Manganiello, V.5
Degerman, E.6
-
112
-
-
33947128224
-
Endocannabinoids and the regulation of their levels in health and disease
-
DOI 10.1097/MOL.0b013e32803dbdec, PII 0004143320070400000003
-
Di Marzo V, Petrosino S (2007) Endocannabinoids and the regulation of their levels in health and disease. Curr Opin Lipidol 18:129-140 (Pubitemid 46412082)
-
(2007)
Current Opinion in Lipidology
, vol.18
, Issue.2
, pp. 129-140
-
-
Di Marzo, V.1
Petrosino, S.2
-
113
-
-
0036838628
-
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine
-
DOI 10.1016/S0006-8993(02)03344-9, PII S0006899302033449
-
González S, Cascio MG, Fernández-Ruiz J, Fezza F, Di Marzo V, Ramos JA (2002) Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. Brain Res 954:73-81 (Pubitemid 35223443)
-
(2002)
Brain Research
, vol.954
, Issue.1
, pp. 73-81
-
-
Gonzalez, S.1
Grazia Cascio, M.2
Fernandez-Ruiz, J.3
Fezza, F.4
Di Marzo, V.5
Ramos, J.A.6
-
114
-
-
40949116660
-
Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury
-
Zhang M, Martin BR, PhD AdlerMW, Razdan RK, Ganea D, Tuma RF (2008) Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury. Neuroscience 152:753-760
-
(2008)
Neuroscience
, vol.152
, pp. 753-760
-
-
Zhang, M.1
Martin, B.R.2
Adlermw, P.3
Razdan, R.K.4
Ganea, D.5
Tuma, R.F.6
-
115
-
-
77951075415
-
Activation of cannabinoid CB2 receptor ameliorates atherosclerosis associated with suppression of adhesion molecules
-
Zhao Y, Yuan Z, Liu Y, Xue J, Tian Y, Liu W, Zhang W, Shen Y, Xu W, Liang X, Chen T (2010) Activation of cannabinoid CB2 receptor ameliorates atherosclerosis associated with suppression of adhesion molecules. J Cardiovasc Pharmacol 55:292-298
-
(2010)
J Cardiovasc Pharmacol
, vol.55
, pp. 292-298
-
-
Zhao, Y.1
Yuan, Z.2
Liu, Y.3
Xue, J.4
Tian, Y.5
Liu, W.6
Zhang, W.7
Shen, Y.8
Xu, W.9
Liang, X.10
Chen, T.11
-
116
-
-
48149101434
-
The endocannabinoid system in obesity and type 2 diabetes
-
Di Marzo V (2008) The endocannabinoid system in obesity and type 2 diabetes. Diabetologia 51:1356-1367
-
(2008)
Diabetologia
, vol.51
, pp. 1356-1367
-
-
Di Marzo, V.1
-
117
-
-
42349112027
-
The endocannabinoid system and the control of glucose homeostasis
-
DOI 10.1111/j.1365-2826.2008.01692.x
-
Nogueiras R, Rohner-Jeanrenaud F, Woods SC, Tschöp MH (2008) The endocannabinoid system and the control of glucose homeostasis. J Neuroendocrinol 20(Suppl 1):147-151 (Pubitemid 351552686)
-
(2008)
Journal of Neuroendocrinology
, vol.20
, Issue.SUPPL. 1
, pp. 147-151
-
-
Nogueiras, R.1
Rohner-Jeanrenaud, F.2
Woods, S.C.3
Tschop, M.H.4
-
118
-
-
35648993493
-
Endocannabinoids and neurodegenerative diseases
-
DOI 10.1016/j.phrs.2007.09.008, PII S1043661807001673, The endocannabinoid system and psychopathology
-
Micale V, Mazzola C, Drago F (2007) Endocannabinoids and neurodegenerative diseases. Pharmacol Res 56(5):382-392 (Pubitemid 350026397)
-
(2007)
Pharmacological Research
, vol.56
, Issue.5
, pp. 382-392
-
-
Micale, V.1
Mazzola, C.2
Drago, F.3
-
120
-
-
0036488182
-
Neuroprotective properties of cannabinoids against oxidative stress: Role of the cannabinoid receptor CB1
-
DOI 10.1046/j.0022-3042.2001.00716.x
-
Marsicano G, Moosmann B, Hermann H, Lutz B, Behl C (2002) Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J Neurochem 80:448-456 (Pubitemid 36383028)
-
(2002)
Journal of Neurochemistry
, vol.80
, Issue.3
, pp. 448-456
-
-
Marsicano, G.1
Moosmann, B.2
Hermann, H.3
Lutz, B.4
Behl, C.5
-
121
-
-
67649843735
-
The endocannabinoid system as a target for the treatment of motor dysfunction
-
Fernández-Ruiz J (2009) The endocannabinoid system as a target for the treatment of motor dysfunction. Br J Pharmacol 156:1029-1040
-
(2009)
Br J Pharmacol
, vol.156
, pp. 1029-1040
-
-
Fernández-Ruiz, J.1
-
122
-
-
0141865717
-
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
-
DOI 10.1126/science.1088208
-
Marsicano G, Goodenough S, Monory K, Hermann H, Eder M, Cannich A, Azad SC, Cascio MG, Gutiérrez SO, van der Stelt M, López-Rodriguez ML, Casanova E, Schütz G, Zieglgänsberger W, Di Marzo V, Behl C, Lutz B (2003) CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 302:84-88 (Pubitemid 37210691)
-
(2003)
Science
, vol.302
, Issue.5642
, pp. 84-88
-
-
Marsicano, G.1
Goodenough, S.2
Monory, K.3
Hermann, H.4
Eder, M.5
Cannich, A.6
Azad, S.C.7
Cascio, M.G.8
Gutierrez, S.O.9
Van Der Stelt, M.10
Lopez-Rodriguez, M.L.11
Casanova, E.12
Schutz, G.13
Zieglgansberger, W.14
Di Marzo, V.15
Behl, C.16
Lutz, B.17
-
123
-
-
26844448746
-
2 receptor in microglial cells in response to inflammatory stimuli
-
DOI 10.1111/j.1471-4159.2005.03380.x
-
Maresz K, Carrier EJ, Ponomarev ED, Hillard CJ, Dittel BN (2005) Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. J Neurochem 95:437-445 (Pubitemid 41457512)
-
(2005)
Journal of Neurochemistry
, vol.95
, Issue.2
, pp. 437-445
-
-
Maresz, K.1
Carrier, E.J.2
Ponomarev, E.D.3
Hillard, C.J.4
Dittel, B.N.5
-
124
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer H, Schaur RJ, Zollner H (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11:81-128 (Pubitemid 121003917)
-
(1991)
Free Radical Biology and Medicine
, vol.11
, Issue.1
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
125
-
-
0031020476
-
A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β- peptide
-
Mark RJ, Lovell MA, Markesbery WR, Uchida K, Mattson MP (1997) A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid b-peptide. J Neurochem 68:255-264 (Pubitemid 26427315)
-
(1997)
Journal of Neurochemistry
, vol.68
, Issue.1
, pp. 255-264
-
-
Mark, R.J.1
Lovell, M.A.2
Markesbery, W.R.3
Uchida, K.4
Mattson, M.P.5
-
126
-
-
0031840571
-
Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system
-
Keller JN, Mattson MP (1998) Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system. Rev Neurosci 9:105-116 (Pubitemid 28386642)
-
(1998)
Reviews in the Neurosciences
, vol.9
, Issue.2
, pp. 105-116
-
-
Keller, J.N.1
Mattson, M.P.2
-
127
-
-
4344617347
-
+-ATPase activity induced by 4-hydroxy-2-nonenal
-
Kadoya A, Miyake H, Ohyashiki T (2003) Contribution of lipid dynamics on the inhibition of bovine brain synaptosomal Na?-K?-ATPase activity induced by 4-hydroxy-2-nonenal. Biol Pharm Bull 26:787-793 (Pubitemid 39655296)
-
(2003)
Biological and Pharmaceutical Bulletin
, vol.26
, Issue.6
, pp. 787-793
-
-
Kadoya, A.1
Miyake, H.2
Ohyashiki, T.3
-
128
-
-
0030316478
-
The role of calcium in the regulation of apoptosis
-
McConkey DJ (1996) The role of calcium in the regulation of apoptosis. Scanning Microsc 10:777-793
-
(1996)
Scanning Microsc
, vol.10
, pp. 777-793
-
-
McConkey, D.J.1
-
129
-
-
79955544309
-
Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network
-
Xu B, Chen S, Luo Y, Chen Z, Liu L, Zhou H, Chen W, Shen T, Han X, Chen L, Huang S (2011) Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network PLoS One. 6:e19052
-
(2011)
PLoS One
, vol.6
-
-
Xu, B.1
Chen, S.2
Luo, Y.3
Chen, Z.4
Liu, L.5
Zhou, H.6
Chen, W.7
Shen, T.8
Han, X.9
Chen, L.10
Huang, S.11
-
130
-
-
0030754962
-
4-hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes
-
DOI 10.1016/S0306-4522(97)00065-1, PII S0306452297000651
-
Keller JN, Mark RJ, Bruce AJ, Blanc E, Rothstein JD, Uchida K, Wäg G, Mattson MP (1997) 4-hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes. Neuroscience 80:685-696 (Pubitemid 27334614)
-
(1997)
Neuroscience
, vol.80
, Issue.3
, pp. 685-696
-
-
Keller, J.N.1
Mark, R.J.2
Bruce, A.J.3
Blanc, E.4
Rothstein, J.D.5
Uchida, K.6
Waeg, G.7
Mattson, M.P.8
-
131
-
-
0035097862
-
Mechanism for obesity-induced increase in myocardial lipid peroxidation
-
DOI 10.1038/sj.ijo.0801536
-
Vincent HK, Powers SK, Dirks AJ, Scarpace PJ (2001) Mechanism for obesity-induced increase in myocardial lipid peroxidation. Int J Obes Relat Metab Disord 25:378-388 (Pubitemid 32209814)
-
(2001)
International Journal of Obesity
, vol.25
, Issue.3
, pp. 378-388
-
-
Vincent, H.K.1
Powers, S.K.2
Dirks, A.J.3
Scarpace, P.J.4
-
132
-
-
0142070953
-
Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: A case of good vs. bad lipids?
-
DOI 10.1016/S0014-5793(03)00875-5
-
Russell AP, Gastaldi G, Bobbioni-Harsch E, Arboit P, Gobelet C, Dériaz O, Golay A, Witztum JL, Giacobino JP (2003) Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids? FEBS Lett 551:104-106 (Pubitemid 37281335)
-
(2003)
FEBS Letters
, vol.551
, Issue.1-3
, pp. 104-106
-
-
Russell, A.P.1
Gastaldi, G.2
Bobbioni-Harsch, E.3
Arboit, P.4
Gobelet, C.5
Deriaz, O.6
Golay, A.7
Witztum, J.L.8
Giacobino, J.-P.9
-
133
-
-
33846805626
-
Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma
-
DOI 10.1016/j.freeradbiomed.2006.12.005, PII S089158490600801X
-
Johnson JB, Summer W, Cutler RG, Martin B, Hyun DH, Dixit VD, Pearson M, Nassar M, Telljohann R, Maudsley S, Carlson O, John S, Laub DR, Mattson MP (2007) Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma. Free Radic Biol Med 42:665-674 (Pubitemid 46205148)
-
(2007)
Free Radical Biology and Medicine
, vol.42
, Issue.5
, pp. 665-674
-
-
Johnson, J.B.1
Summer, W.2
Cutler, R.G.3
Martin, B.4
Hyun, D.-H.5
Dixit, V.D.6
Pearson, M.7
Nassar, M.8
Tellejohan, R.9
Maudsley, S.10
Carlson, O.11
John, S.12
Laub, D.R.13
Mattson, M.P.14
-
134
-
-
34247361278
-
Carbonylation of adipose proteins in obesity and insulin resistance: Identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal
-
DOI 10.1074/mcp.M600120-MCP200
-
Grimsrud PA, Picklo MJ Sr, Griffin TJ, Bernlohr DA (2007) Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal. Mol Cell Proteomics 6:624-637 (Pubitemid 46630095)
-
(2007)
Molecular and Cellular Proteomics
, vol.6
, Issue.4
, pp. 624-637
-
-
Grimsrud, P.A.1
Picklo Sr., M.J.2
Griffin, T.J.3
Bernlohr, D.A.4
-
135
-
-
34248598495
-
The lipid peroxidation end-product 4-HNE induces COX-2 expression through p38MAPK activation in 3T3-L1 adipose cell
-
DOI 10.1016/j.febslet.2007.04.048, PII S001457930700436X
-
Zarrouki B, Soares AF, Guichardant M, Lagarde M, Géloën A (2007) The lipid peroxidation end-product 4-HNE induces COX-2 expression through p38MAPK activation in 3T3-L1 adipose cell. FEBS Lett 581:2394-2400 (Pubitemid 46764695)
-
(2007)
FEBS Letters
, vol.581
, Issue.13
, pp. 2394-2400
-
-
Zarrouki, B.1
Soares, A.F.2
Guichardant, M.3
Lagarde, M.4
Geloen, A.5
-
136
-
-
70349236876
-
Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders
-
Mattson MP (2009) Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders. Exp Gerontol 44:625-633
-
(2009)
Exp Gerontol
, vol.44
, pp. 625-633
-
-
Mattson, M.P.1
-
137
-
-
41149143613
-
Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice
-
DOI 10.1021/bi702124u
-
Singh SP, Niemczyk M, Saini D, Awasthi YC, Zimniak L, Zimniak P (2008) Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. Biochemistry 47:3900-3911 (Pubitemid 351431379)
-
(2008)
Biochemistry
, vol.47
, Issue.12
, pp. 3900-3911
-
-
Singh, S.P.1
Niemczyk, M.2
Saini, D.3
Awasthi, Y.C.4
Zimniak, L.5
Zimniak, P.6
-
138
-
-
43849102129
-
High-fat, energy-dense, fast-food-style breakfast results in an increase in oxidative stress in metabolic syndrome
-
DOI 10.1016/j.metabol.2008.02.016, PII S0026049508000875
-
Devaraj S, Wang-Polagruto J, Polagruto J, Keen CL, Jialal I (2008) High-fat, energy-dense, fast-food-style breakfast results in an increase in oxidative stress in metabolic syndrome. Metabolism 57:867-870 (Pubitemid 351697920)
-
(2008)
Metabolism: Clinical and Experimental
, vol.57
, Issue.6
, pp. 867-870
-
-
Devaraj, S.1
Wang-Polagruto, J.2
Polagruto, J.3
Keen, C.L.4
Jialal, I.5
-
139
-
-
0035231707
-
Plasma levels of soluble vascular adhesion molecule-1 and cholesterol oxidation product in type 2 diabetic patients with nephropathy
-
Murakami H, Tamasawa N, Matsui J, Yamato K, JingZhi G, Suda T (2001) Plasma levels of soluble vascular adhesion molecule-1 and cholesterol oxidation product in type 2 diabetic patients with nephropathy. J Atheroscler Thromb 8:21-24
-
(2001)
J Atheroscler Thromb
, vol.8
, pp. 21-24
-
-
Murakami, H.1
Tamasawa, N.2
Matsui, J.3
Yamato, K.4
Jingzhi, G.5
Suda, T.6
-
140
-
-
33646410697
-
Can the liver X receptor work its magic in skeletal muscle too?
-
Krook A (2006) Can the liver X receptor work its magic in skeletal muscle too? Diabetologia 49:819-821
-
(2006)
Diabetologia
, vol.49
, pp. 819-821
-
-
Krook, A.1
-
141
-
-
33644850701
-
Oxidized LDL and abdominal obesity: A key to understanding the metabolic syndrome
-
Knopp RH, Paramsothy P (2006) Oxidized LDL and abdominal obesity: a key to understanding the metabolic syndrome. Am J Clin Nutr 83:1-2 (Pubitemid 44699225)
-
(2006)
American Journal of Clinical Nutrition
, vol.83
, Issue.1
, pp. 1-2
-
-
Knopp, R.H.1
Paramsothy, P.2
-
142
-
-
2342520613
-
Lipid arrays: New tools in the understanding of membrane dynamics and lipid signaling
-
DOI 10.1124/mi.4.2.6
-
Ivanova PT, Milne SB, Forrester JS, Brown HA (2004) LIPID arrays: new tools in the understanding of membrane dynamics and lipid signaling. Mol Interv 4:86-96 (Pubitemid 38584971)
-
(2004)
Molecular Interventions
, vol.4
, Issue.2
, pp. 86-96
-
-
Ivanova, P.T.1
Milne, S.B.2
Forrester, J.S.3
Brown, H.A.4
Armstrong, M.D.5
-
143
-
-
0027471304
-
Central adiposity and increased risk of coronary artery disease mortality in older women
-
Prineas RJ, Folsom AR, Kaye SA (1993) Central adiposity and increased risk of coronary artery disease mortality in older women. Ann Epidemiol 3:35-41 (Pubitemid 23050727)
-
(1993)
Annals of Epidemiology
, vol.3
, Issue.1
, pp. 35-41
-
-
Prineas, R.J.1
Folsom, A.R.2
Kaye, S.A.3
-
144
-
-
1242291791
-
Clinical Importance of Obesity Versus the Metabolic Syndrome in Cardiovascular Risk in Women: A Report from the Women's Ischemia Syndrome Evaluation (WISE) Study
-
DOI 10.1161/01.CIR.0000115514.44135.A8
-
Kip KE, Morroguin OC, Kelley DE, Johnson BP, Kelsey SF, Shaw LJ, Rogers WJ, Reis SE (2004) Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) study. Circulation 109:706-713 (Pubitemid 38222888)
-
(2004)
Circulation
, vol.109
, Issue.6
, pp. 706-713
-
-
Kip, K.E.1
Marroquin, O.C.2
Kelley, D.E.3
Johnson, B.D.4
Kelsey, S.F.5
Shaw, L.J.6
Rogers, W.J.7
Reis, S.E.8
-
145
-
-
34848911661
-
Metabolic syndrome as a risk factor for coronary heart disease and stroke: An 11-year prospective cohort in Taiwan community
-
Chien KL, Hsu HC, Sung FC, Su TC, Chen MF, Lee YT (2007) Metabolic syndrome as a risk factor for coronary heart disease and stroke: an 11-year prospective cohort in Taiwan community. Atherosclerosis 194:214-221
-
(2007)
Atherosclerosis
, vol.194
, pp. 214-221
-
-
Chien, K.L.1
Hsu, H.C.2
Sung, F.C.3
Su, T.C.4
Chen, M.F.5
Lee, Y.T.6
-
146
-
-
44849127652
-
Body mass index and magnetic resonance markers of brain integrity in adults
-
Gazdzinski S, Kornak J, Weiner MW, Meyerhoff DJ (2008) Body mass index and magnetic resonance markers of brain integrity in adults. Ann Neurol 63:652-657
-
(2008)
Ann Neurol
, vol.63
, pp. 652-657
-
-
Gazdzinski, S.1
Kornak, J.2
Weiner, M.W.3
Meyerhoff, D.J.4
-
147
-
-
54249156545
-
Metabolic syndrome: From epidemiology to systems biology
-
Lusis AJ, Attie AD, Reue K (2008) Metabolic syndrome: from epidemiology to systems biology. Nat Rev Genet 9:819-830
-
(2008)
Nat Rev Genet
, vol.9
, pp. 819-830
-
-
Lusis, A.J.1
Attie, A.D.2
Reue, K.3
-
148
-
-
27844600646
-
Metabolic syndrome as a predictor of ischemic stroke in elderly persons
-
DOI 10.2169/internalmedicine.44.922
-
Kawamoto R, Tomita H, Oka Y, Kodama A (2005) Metabolic syndrome as a predictor of ischemic stroke in elderly persons. Intern Med 44:922-927 (Pubitemid 41644088)
-
(2005)
Internal Medicine
, vol.44
, Issue.9
, pp. 922-927
-
-
Kawamoto, R.1
Tomita, H.2
Oka, Y.3
Kodama, A.4
-
149
-
-
0038642367
-
Diagnosis, prevention, and intervention for the metabolic syndrome
-
DOI 10.1016/S0002-9149(03)00507-1
-
Scott CL (2003) Diagnosis, prevention, and intervention for the metabolic syndrome. Am J Cardiol 92:35i-42i (Pubitemid 36831113)
-
(2003)
American Journal of Cardiology
, vol.92
, Issue.1 SUPPL.
-
-
Scott, C.L.1
-
150
-
-
12844262139
-
The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study
-
DOI 10.2337/diacare.28.2.385
-
McNeill A, Rosamond W, Girman C, Golden S, Schmidt MI, East H, Ballantyne C, Heiss G (2005) The metabolic syndrome and 11-year risk of incident cardiovascular disease in the Atherosclerosis Risk in Communities Study. Diabetes Care 28:385-390 (Pubitemid 40170944)
-
(2005)
Diabetes Care
, vol.28
, Issue.2
, pp. 385-390
-
-
McNeill, A.M.1
Rosamond, W.D.2
Girman, C.J.3
Golden, S.H.4
Schmidt, M.I.5
East, H.E.6
Ballantyne, C.M.7
Heiss, G.8
-
151
-
-
28944434431
-
Metabolic syndrome vs Framingham risk score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus
-
DOI 10.1001/archinte.165.22.2644
-
Wannamethee SG, Shaper AG, Lennon L, Morris RW (2005) Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus. Arch Intern Med 165:2644-2650 (Pubitemid 41785063)
-
(2005)
Archives of Internal Medicine
, vol.165
, Issue.22
, pp. 2644-2650
-
-
Wannamethee, S.G.1
Shaper, A.G.2
Lennon, L.3
Morris, R.W.4
-
152
-
-
38149012414
-
Metabolic syndrome and ischemic stroke risk: Northern Manhattan Study
-
Boden-Albala B, Sacco RL, Lee HS, Grahame-Clarke C, Rundek T, Elkind MV, Wright C, Giardina EG, DiTullio MR, Homma S, Paik MC (2008) Metabolic syndrome and ischemic stroke risk: Northern Manhattan Study. Stroke 39:30-35
-
(2008)
Stroke
, vol.39
, pp. 30-35
-
-
Boden-Albala, B.1
Sacco, R.L.2
Lee, H.S.3
Grahame-Clarke, C.4
Rundek, T.5
Elkind, M.V.6
Wright, C.7
Giardina, E.G.8
Ditullio, M.R.9
Homma, S.10
Paik, M.C.11
-
154
-
-
0035006350
-
Increased basal levels of plasma nitric oxide in Type 2 diabetic subjects: Relationship to microvascular complications
-
DOI 10.1016/S1056-8727(01)00144-1
-
Maejima K, Nakano S, Himeno M, Tsuda S, Makiishi H, Ito T, Nakagawa A, Kigoshi T, Ishibashi T, Nishio M, Uchida K (2001) Increased basal levels of plasma nitric oxide in type 2 diabetic subjects: relationship to microvascular complications. J Diabetes Complications 15:135-143 (Pubitemid 32453170)
-
(2001)
Journal of Diabetes and its Complications
, vol.15
, Issue.3
, pp. 135-143
-
-
Maejima, K.1
Nakano, S.2
Himeno, M.3
Tsuda, S.-I.4
Makiishi, H.5
Ito, T.6
Nakagawa, A.7
Kigoshi, T.8
Ishibashi, T.9
Nishio, M.10
Uchida, K.11
-
155
-
-
0036136898
-
Endothelial dysfunction and stroke
-
Cosentino F, Rubattu S, Savoia C, Venturelli V, Pagannonne E, Volpe M (2001) Endothelial dysfunction and stroke. J Cardiovasc Pharmacol 38(Suppl 2):S75-S78 (Pubitemid 34020562)
-
(2002)
Journal of Cardiovascular Pharmacology
, vol.38
, Issue.SUPPL. 2
-
-
Cosentino, F.1
Rubattu, S.2
Savoia, C.3
Venturelli, V.4
Pagannonne, E.5
Volpe, M.6
-
156
-
-
33645337656
-
Blunted response to systemic nitric oxide synthase inhibition in the cerebral circulation of patients with type 2 diabetes
-
Nazir FS, Alem M, Small M, Connell JM, Lees KR, Walters MR, Cleland SJ (2006) Blunted response to systemic nitric oxide synthase inhibition in the cerebral circulation of patients with type 2 diabetes. Diabet Med 23:398-402
-
(2006)
Diabet Med
, vol.23
, pp. 398-402
-
-
Nazir, F.S.1
Alem, M.2
Small, M.3
Connell, J.M.4
Lees, K.R.5
Walters, M.R.6
Cleland, S.J.7
-
157
-
-
0029921450
-
Plateletdependent thrombin generation in patients with diabetes mellitus:
-
Aoki I, Shimoyama K, Aoki N, Homori M, Yanagisawa A, Nakahara K, Kawai Y, Kitamura SI, Ishikawa K (1996) Plateletdependent thrombin generation in patients with diabetes mellitus: effects of glycemic control on coagulability in diabetes. J Am Coll Cardiol 27:560-566
-
(1996)
J Am Coll Cardiol
, vol.27
, pp. 560-566
-
-
Aoki, I.1
Shimoyama, K.2
Aoki, N.3
Homori, M.4
Yanagisawa, A.5
Nakahara, K.6
Kawai, Y.7
Kitamura, S.I.8
Ishikawa, K.9
-
158
-
-
0027049709
-
Thrombin-antithrombin III complexes in type II diabetes mellitus
-
DOI 10.1016/1056-8727(92)90042-J
-
Davi G, Gennaro F, Spatola A, Catalano I, Averna M, Montalto G, Amato S, Notarbartolo A (1992) Thrombin-antithrombin III complexes in type II diabetes mellitus. J Diabetes Complicat 6:7-11 (Pubitemid 23034744)
-
(1992)
Journal of Diabetes and its Complications
, vol.6
, Issue.1
, pp. 7-11
-
-
Davi, G.1
Gennaro, F.2
Spatola, A.3
Catalano, I.4
Averna, M.5
Montalto, G.6
Amato, S.7
Notarbartolo, A.8
-
159
-
-
0344011158
-
Association of inflammation markers with impaired insulin sensitivity and coagulative activation in obese healthy women
-
DOI 10.1210/jc.2003-030508
-
Romano M, Guagnano MT, Pacini G, Vigneri S, Falco A, Marinopiccoli M, Manigrasso MR, Basili S, Davi G (2003) Association of inflammation markers with impaired insulin sensitivity and coagulative activation in obese healthy women. J Clin Endocrinol Metab 88:5321-5326 (Pubitemid 37452734)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.11
, pp. 5321-5326
-
-
Romano, M.1
Guagnano, M.T.2
Pacini, G.3
Vigneri, S.4
Falco, A.5
Marinopiccoli, M.6
Manigrasso, M.R.7
Basili, S.8
Davi, G.9
-
160
-
-
28344441841
-
2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study
-
DOI 10.1001/archinte.165.21.2479
-
Ballantyne CM, Hoogeveen RC, Bang H, Coresh J, Folsom AR, Chambless LE, Myerson M, Wu KK, Sharrett AR, Boerwinkle E (2005) Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study. Arch Intern Med 165:2479-2484 (Pubitemid 41720009)
-
(2005)
Archives of Internal Medicine
, vol.165
, Issue.21
, pp. 2479-2484
-
-
Ballantyne, C.M.1
Hoogeveen, R.C.2
Bang, H.3
Coresh, J.4
Folsom, A.R.5
Chambless, L.E.6
Myerson, M.7
Wu, K.K.8
Sharrett, A.R.9
Boerwinkle, E.10
-
161
-
-
0037312855
-
Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: A population-based study
-
DOI 10.2337/diabetes.52.2.442
-
Engstrom G, Stavenow L, Hedblad B, Lind P, Eriksson KF, Janzon L, Lindgarde F (2003) Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: a population-based study. Diabetes 52:442-447 (Pubitemid 36173201)
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 442-447
-
-
Engstrom, G.1
Stavenow, L.2
Hedblad, B.3
Lind, P.4
Eriksson, K.-F.5
Janzon, L.6
Lindgarde, F.7
-
162
-
-
0028848187
-
Impaired insulin-induced platelet antiaggregating effect in obesity and in obese NIDDM patients
-
Trovati M, Mularoni EM, Burzacca S, Ponziani MC, Massucco P, Mattiello L, Piretto V, Cavalot F, Anfossi G (1995) Impaired insulin-induced platelet antiaggregating effect in obesity and in obese NIDDM patients. Diabetes 44:1318-1322
-
(1995)
Diabetes
, vol.44
, pp. 1318-1322
-
-
Trovati, M.1
Mularoni, E.M.2
Burzacca, S.3
Ponziani, M.C.4
Massucco, P.5
Mattiello, L.6
Piretto, V.7
Cavalot, F.8
Anfossi, G.9
-
163
-
-
0030963302
-
Duration of diabetes and carotid wall thickness: The Insulin Resistance Atherosclerosis Study (IRAS)
-
Wagenknecht LE, D'Agostino R Jr, Savage PJ, O'Leary DH, Saad MF, Haffner SM (1997) Duration of diabetes and carotid wall thickness: the Insulin Resistance Atherosclerosis Study (IRAS). Stroke 28:999-1005 (Pubitemid 27209149)
-
(1997)
Stroke
, vol.28
, Issue.5
, pp. 999-1005
-
-
Wagenknecht, L.E.1
D'Agostino Jr., R.2
Savage, P.J.3
O'Leary, D.H.4
Saad, M.F.5
Haffner, S.M.6
-
164
-
-
27844472159
-
Increased risk of Alzheimer's disease in type II diabetes: Insulin resistance of the brain or insulin-induced amyloid pathology?
-
DOI 10.1042/BST20051041
-
Biessels GJ, Kappelle LJ (2005) Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology? Biochem Soc Trans 33:1041-1044 (Pubitemid 41659109)
-
(2005)
Biochemical Society Transactions
, vol.33
, Issue.5
, pp. 1041-1044
-
-
Biessels, G.J.1
Kappelle, L.J.2
-
165
-
-
5344256250
-
Hyperinsulinemia and risk of Alzheimer disease
-
Luchsinger JA, Tang MX, Shea S, Mayeux R (2004) Hyperinsulinemia and risk of Alzheimer disease. Neurology 63:1187-1192 (Pubitemid 39350015)
-
(2004)
Neurology
, vol.63
, Issue.7
, pp. 1187-1192
-
-
Luchsinger, J.A.1
Tang, M.-X.2
Shea, S.3
Mayeux, R.4
-
166
-
-
0035871641
-
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
-
Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H (2001) Stimulation of betaamyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci 21:2561-2570 (Pubitemid 32298198)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.8
, pp. 2561-2570
-
-
Gasparini, L.1
Gouras, G.K.2
Wang, R.3
Gross, R.S.4
Beal, M.F.5
Greengard, P.6
Xu, H.7
-
167
-
-
0034038036
-
Degradation of soluble amyloid β-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains
-
DOI 10.1023/A:1007527721160
-
Perez A, Morell L, Cresto JC, Castano EM (2000) Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains. Neurochem Res 25:247-255 (Pubitemid 30210091)
-
(2000)
Neurochemical Research
, vol.25
, Issue.2
, pp. 247-255
-
-
Perez, A.1
Morelli, L.2
Cresto, J.C.3
Castano, E.M.4
-
168
-
-
19944433845
-
β-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways
-
DOI 10.1111/j.1471-4159.2004.02895.x
-
Tamagno E, Parola M, Bardini P, Piccini A, Borghi R, Guglielmotto M, Santoro G, Davit A, Danni O, Smith MA, Perry G, Tabaton M (2005) Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways. J Neurochem 92:628-636 (Pubitemid 40189465)
-
(2005)
Journal of Neurochemistry
, vol.92
, Issue.3
, pp. 628-636
-
-
Tamagno, E.1
Parola, M.2
Bardini, P.3
Piccini, A.4
Borghi, R.5
Guglielmotto, M.6
Santoro, G.7
Davit, A.8
Danni, O.9
Smith, M.A.10
Perry, G.11
Tabaton, M.12
-
169
-
-
33747104566
-
Links between Alzheimer's disease and diabetes
-
DOI 10.1358/dot.2006.42.7.973588
-
Sun MK, Alkon DL (2006) Links between Alzheimer's disease and diabetes. Drugs Today (Barc) 42:481-489 (Pubitemid 44221017)
-
(2006)
Drugs of Today
, vol.42
, Issue.7
, pp. 481-489
-
-
Sun, M.-K.1
Alkon, D.L.2
-
170
-
-
1542752823
-
Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease
-
Grossman H (2003) Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease. CNS Spectr 8:815-823
-
(2003)
CNS Spectr
, vol.8
, pp. 815-823
-
-
Grossman, H.1
-
171
-
-
75149178824
-
Insulin resistance in Alzheimer's diseasë
-
Taylor and Francis, London
-
Craft S, Reger MA, Baker LD (2006) Insulin resistance in Alzheimer's diseasë. Alzheimer's disease and related disorders Annual 5. Taylor and Francis, London, pp 111-133
-
(2006)
Alzheimer's Disease and Related Disorders Annual
, vol.5
, pp. 111-133
-
-
Craft, S.1
Reger, M.A.2
Baker, L.D.3
-
172
-
-
33846989295
-
Impaired insulin signaling and the pathogenesis of Alzheimer's disease
-
Revill P, Moral M, Prous JR (2006) Impaired insulin signaling and the pathogenesis of Alzheimer's disease. Drug Today 42:785-790
-
(2006)
Drug Today
, vol.42
, pp. 785-790
-
-
Revill, P.1
Moral, M.2
Prous, J.R.3
-
173
-
-
34548711907
-
Type 2 diabetes and risk of cognitive impairment and dementia
-
DOI 10.1007/s11910-007-0058-7
-
Whitmer RA (2007) Type 2 diabetes and risk of cognitive impairment and dementia. Curr Neurol Neurosci Rep 7:373-380 (Pubitemid 47422778)
-
(2007)
Current Neurology and Neuroscience Reports
, vol.7
, Issue.5
, pp. 373-380
-
-
Whitmer, R.A.1
-
174
-
-
77953089836
-
Metabolic syndrome abnormalities are associated with severity of anxiety and depression and with tricyclic antidepressant use
-
van Reedt Dortland AK, Giltay EJ, van Veen T, Zitman FG, Penninx BW (2010) Metabolic syndrome abnormalities are associated with severity of anxiety and depression and with tricyclic antidepressant use. Acta Psychiatr Scand 122:30-39
-
(2010)
Acta Psychiatr Scand
, vol.122
, pp. 30-39
-
-
Van Reedt Dortland, A.K.1
Giltay, E.J.2
Van Veen, T.3
Zitman, F.G.4
Penninx, B.W.5
-
175
-
-
77956207020
-
The association between conventional antidepressants and the metabolic syndrome: A review of the evidence and clinical implications
-
McIntyre RS, Park KY, Law CW, Sultan F, Adams A, Lourenco MT, Lo AK, Soczynska JK, Woldeyohannes H, Alsuwaidan M, Yoon J, Kennedy SH (2010) The association between conventional antidepressants and the metabolic syndrome: a review of the evidence and clinical implications. CNS Drugs 24:741-753
-
(2010)
CNS Drugs
, vol.24
, pp. 741-753
-
-
McIntyre, R.S.1
Park, K.Y.2
Law, C.W.3
Sultan, F.4
Adams, A.5
Lourenco, M.T.6
Lo, A.K.7
Soczynska, J.K.8
Woldeyohannes, H.9
Alsuwaidan, M.10
Yoon, J.11
Kennedy, S.H.12
-
176
-
-
17444366914
-
Genes, stress, and depression
-
DOI 10.1016/j.metabol.2005.01.007, Depression: enetics, Pathophysiology, and Clinical Manifestations
-
Wurtman RJ (2005) Genes, stress, and depression. Metabolism 54(5 Suppl 1):16-19 (Pubitemid 40546017)
-
(2005)
Metabolism: Clinical and Experimental
, vol.54
, Issue.5 SUPPL.
, pp. 16-19
-
-
Wurtman, R.J.1
-
177
-
-
38649105517
-
Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR)
-
DOI 10.1007/s10519-007-9172-1
-
Brummett BH, Boyle SH, Siegler IC, Kuhn CM, Ashley-Koch A, Jonassaint CR, Züchner S, Collins A, Williams RB (2008) Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR). Behav Genet 38:34-43 (Pubitemid 351164912)
-
(2008)
Behavior Genetics
, vol.38
, Issue.1
, pp. 34-43
-
-
Brummett, B.H.1
Boyle, S.H.2
Siegler, I.C.3
Kuhn, C.M.4
Ashley-Koch, A.5
Jonassaint, C.R.6
Zuchner, S.7
Collins, A.8
Williams, R.B.9
-
178
-
-
67649717023
-
The psychoneuroimmunology of depression
-
Leonard BE, Myint A (2009) The psychoneuroimmunology of depression. Hum Psychopharmacol 24:165-175
-
(2009)
Hum Psychopharmacol
, vol.24
, pp. 165-175
-
-
Leonard, B.E.1
Myint, A.2
-
179
-
-
60849106515
-
Cascading effects of stressors and inflammatory immune system activation: Implications for major depressive disorder
-
Anisman H (2009) Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder. J Psychiatry Neurosci 34:4-20
-
(2009)
J Psychiatry Neurosci
, vol.34
, pp. 4-20
-
-
Anisman, H.1
-
180
-
-
23644431529
-
The stress system in the human brain in depression and neurodegeneration
-
DOI 10.1016/j.arr.2005.03.003, PII S1568163705000048, Stress, Neuropeptides and Age-Related Diseases
-
Swaab DF, Bao AM, Lucassen PJ (2005) The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 4:141-194 (Pubitemid 41114861)
-
(2005)
Ageing Research Reviews
, vol.4
, Issue.2
, pp. 141-194
-
-
Swaab, D.F.1
Bao, A.-M.2
Lucassen, P.J.3
-
181
-
-
50449094193
-
IGF-1 regulates cAMP levels in astrocytes through a beta2-adrenergic receptordependant mechanism
-
Chesik D, Wilczak N, De Keyser J (2008) IGF-1 regulates cAMP levels in astrocytes through a beta2-adrenergic receptordependant mechanism. Int J Med Sci 5:240-243
-
(2008)
Int J Med Sci
, vol.5
, pp. 240-243
-
-
Chesik, D.1
Wilczak, N.2
De Keyser, J.3
-
182
-
-
77956102243
-
Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis
-
Robertson SD, Matthies HJ, Owens WA, Sathananthan V, Christianson NS, Kennedy JP, Lindsley CW, Daws LC, Galli A (2010) Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis. J Neurosci 30:11305-11316
-
(2010)
J Neurosci
, vol.30
, pp. 11305-11316
-
-
Robertson, S.D.1
Matthies, H.J.2
Owens, W.A.3
Sathananthan, V.4
Christianson, N.S.5
Kennedy, J.P.6
Lindsley, C.W.7
Daws, L.C.8
Galli, A.9
-
183
-
-
79957961825
-
Late-life depression and Alzheimer's disease: The glutamatergic system inside of this mirror relationship
-
Frisardi V, Panza F, Farooqui AA (2011) Late-life depression and Alzheimer's disease: the glutamatergic system inside of this mirror relationship. Brain Res Rev 67:344-355
-
(2011)
Brain Res Rev
, vol.67
, pp. 344-355
-
-
Frisardi, V.1
Panza, F.2
Farooqui, A.A.3
-
184
-
-
74949087576
-
Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia
-
Bardgett ME, McCarthy JJ, Stocker SD (2010) Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia. Hypertension 55:284-290
-
(2010)
Hypertension
, vol.55
, pp. 284-290
-
-
Bardgett, M.E.1
McCarthy, J.J.2
Stocker, S.D.3
-
185
-
-
77649251242
-
Altered balance of gamma-aminobutyric acidergic and glutamatergic afferent inputs in rostral ventrolateral medulla-projecting neurons in the paraventricular nucleus of the hypothalamus of renovascular hypertensive rats
-
Biancardi VC, Campos RR, Stern JE (2010) Altered balance of gamma-aminobutyric acidergic and glutamatergic afferent inputs in rostral ventrolateral medulla-projecting neurons in the paraventricular nucleus of the hypothalamus of renovascular hypertensive rats. J Comp Neurol 518:567-585
-
(2010)
J Comp Neurol
, vol.518
, pp. 567-585
-
-
Biancardi, V.C.1
Campos, R.R.2
Stern, J.E.3
-
186
-
-
79956048714
-
Composition of fatty acids in plasma and erythrocytes and eicosanoids level in patients with metabolic syndrome
-
Novgorodtseva TP, Karaman YK, Zhukova NV, Lobanova EG, Antonyuk MV, Kantur TA (2011) Composition of fatty acids in plasma and erythrocytes and eicosanoids level in patients with metabolic syndrome. Lipids Health Dis 10:82
-
(2011)
Lipids Health Dis
, vol.10
, pp. 82
-
-
Novgorodtseva, T.P.1
Karaman, Y.K.2
Zhukova, N.V.3
Lobanova, E.G.4
Antonyuk, M.V.5
Kantur, T.A.6
-
187
-
-
79959736389
-
Oncostatin M produced in Kupffer cells in response to PGE2: Possible contributor to hepatic insulin resistance and steatosis
-
Henkel J, Gärtner D, Dorn C, Hellerbrand C, Schanze N, Elz SR, Püschel GP (2011) Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis. Lab Invest 91:1107-1117
-
(2011)
Lab Invest
, vol.91
, pp. 1107-1117
-
-
Henkel, J.1
Gärtner, D.2
Dorn, C.3
Hellerbrand, C.4
Schanze, N.5
Elz, S.R.6
Püschel, G.P.7
-
188
-
-
25444473871
-
Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients
-
DOI 10.1002/jnr.20487
-
McLarnon JG, Choi HB, Lue LF, Walker DG, Kim SU (2005) Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients. J Neurosci Res 81:426-435 (Pubitemid 41359297)
-
(2005)
Journal of Neuroscience Research
, vol.81
, Issue.3
, pp. 426-435
-
-
McLarnon, J.G.1
Choi, H.B.2
Lue, L.-F.3
Walker, D.G.4
Kim, S.U.5
-
189
-
-
78651500448
-
Serum platelet-activating factor acetylhydrolase activity: Relationship with metabolic syndrome in women with history of gestational diabetes mellitus
-
Derbent A, Kargili A, Koca C, Gümüş II?, Sevgili S, Simavli S, Karakurt F, Turhan NÖ (2011) Serum platelet-activating factor acetylhydrolase activity: relationship with metabolic syndrome in women with history of gestational diabetes mellitus. Gynecol Endocrinol 27:128-133
-
(2011)
Gynecol Endocrinol
, vol.27
, pp. 128-133
-
-
Derbent, A.1
Kargili, A.2
Koca, C.3
Gümüş, I.I.4
Sevgili, S.5
Simavli, S.6
Karakurt, F.7
Nö, T.8
-
190
-
-
84860493578
-
Lipid mediators of insulin resistance
-
Holland WL, Knotts TA, Chavez JA, Wang LP, Hoehn KL, Summers SA (2007) Lipid mediators of insulin resistance. Nutr Rev 65:S39-S46
-
(2007)
Nutr Rev
, vol.65
-
-
Holland, W.L.1
Knotts, T.A.2
Chavez, J.A.3
Wang, L.P.4
Hoehn, K.L.5
Summers, S.A.6
-
191
-
-
57349148715
-
Oxysterol as a marker of atherogenic dyslipidemia in adolescence
-
DOI 10.1210/jc.2008-0586
-
Alkazemi D, Egeland G, Vaya J, Meltzer S, Kubow S (2008) Oxysterol as a marker of atherogenic dyslipidemia in adolescence. J Clin Endocrinol Metab 93:4282-4289 (Pubitemid 352789523)
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, Issue.11
, pp. 4282-4289
-
-
Alkazemi, D.1
Egeland, G.2
Vaya, J.3
Meltzer, S.4
Kubow, S.5
|