4-hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes

Neuroscience

Volumn 80, Issue 3, 1997, Pages 685-696

  Keller, J N ^a,b   Mark, R J ^a   Bruce, A J ^a   Blanc, E ^a   Rothstein, J D ^c   Uchida, K ^d   Waeg, G ^e   Mattson, M P ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NAGOYA UNIVERSITY   (Japan)

^e UNIVERSITY OF GRAZ   (Austria)

Author keywords

Alzheimer's disease; Amyloid peptide; Antioxidants; Excitotoxicity; Mitochondrial respiration

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE; ANTIOXIDANT; GLUTAMIC ACID;

AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; LIPID PEROXIDATION; LONG TERM POTENTIATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION; SYNAPTOSOME;

ALDEHYDES; AMINO ACID TRANSPORT SYSTEM X-AG; ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CEREBRAL CORTEX; CROSS-LINKING REAGENTS; FEMALE; FERROUS COMPOUNDS; GLUTAMIC ACID; GLUTATHIONE; KINETICS; MITOCHONDRIA; OXIDATIVE STRESS; PROPYL GALLATE; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTOSOMES;

EID: 0030754962     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00065-1     Document Type: Article

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