Metabolic syndrome abnormalities are associated with severity of anxiety and depression and with tricyclic antidepressant use

Acta Psychiatrica Scandinavica

Volumn 122, Issue 1, 2010, Pages 30-39

  Van Reedt Dortland, A K B ^a   Giltay, E J ^a   Van Veen, T ^a   Zitman, F G ^a   Penninx, B W J H ^a,b,c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Abdominal obesity; Anxiety; Depression; Dyslipidemia; Metabolic syndrome; Tricyclic antidepressants

Indexed keywords

TRICYCLIC ANTIDEPRESSANT AGENT;

ABDOMINAL OBESITY; ADULT; AGED; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG USE; DYSLIPIDEMIA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PRIORITY JOURNAL; ANXIETY; COMORBIDITY; COMPARATIVE STUDY; CORONARY ARTERY DISEASE; HYPERTENSION; MIDDLE AGED; OBESITY, ABDOMINAL; PREVALENCE; SEVERITY OF ILLNESS INDEX;

ADULT; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ANXIETY; COMORBIDITY; CORONARY ARTERY DISEASE; DEPRESSION; FEMALE; HUMANS; HYPERTENSION; MALE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY, ABDOMINAL; PREVALENCE; SEVERITY OF ILLNESS INDEX;

EID: 77953089836     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/j.1600-0447.2010.01565.x     Document Type: Article

References (57)

1. Grundy SM, Cleeman JI, Daniels SR et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005 112 : 2735 2752.
2. Third Report of the National Cholesterol Education Program (NCEP). Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation 2002 106 : 3143 3421.
3. Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006 367 : 1747 1757.
4. Ford ES, Giles WH, Mokdad AH. Increasing prevalence of the metabolic syndrome among U.S. adults. Diabetes Care 2004 27 : 2444 2449.
5. Whooley MA, De Jonge P, Vittinghoff E et al. Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA 2008 300 : 2379 2388.
6. Kubzansky LD, Kawachi I, Weiss ST, Sparrow D. Anxiety and coronary heart disease: a synthesis of epidemiological, psychological, and experimental evidence. Ann Behav Med 1998 20 : 47 58.
7. Kinder LS, Carnethon MR, Palaniappan LP, King AC, Fortmann SP. Depression and the metabolic syndrome in young adults: findings from the Third National Health and Nutrition Examination Survey. Psychosom Med 2004 66 : 316 322.
8. Skilton MR, Moulin P, Terra JL, Bonnet F. Associations between anxiety, depression, and the metabolic syndrome. Biol Psychiatry 2007 62 : 1251 1257.
9. Vogelzangs N, Suthers K, Ferrucci L et al. Hypercortisolemic depression is associated with the metabolic syndrome in late-life. Psychoneuroendocrinology 2007 32 : 151 159.
10. Lehto SM, Heiskanen T, Hintikka J et al. Metabolic syndrome - the impact of depression. Ann Epidemiol 2008 18 : 871.
11. Koponen H, Jokelainen J, Keinanen-Kiukaanniemi S, Kumpusalo E, Vanhala M. Metabolic syndrome predisposes to depressive symptoms: a population-based 7-year follow-up study. J Clin Psychiatry 2008 69 : 178 182.
12. Vanhala M, Jokelainen J, Keinanen-Kiukaanniemi S, Kumpusalo E, Koponen H. Depressive symptoms predispose females to metabolic syndrome: a 7-year follow-up study. Acta Psychiatr Scand 2008 119 : 137 142.
13. Dunbar JA, Reddy P, Davis-Lameloise N et al. Depression: an important comorbidity with metabolic syndrome in a general population. Diabetes Care 2008 31 : 2368 2373.
14. Akbaraly TN, Kivimaki M, Brunner EJ et al. Association between metabolic syndrome and depressive symptoms in middle-aged adults: results from the Whitehall II study. Diabetes Care 2009 32 : 499 504.
15. Capuron L, Su S, Miller AH et al. Depressive symptoms and metabolic syndrome: is inflammation the underlying link? Biol Psychiatry 2008 64 : 896 900.
16. Raikkonen K, Matthews KA, Kuller LH. The relationship between psychological risk attributes and the metabolic syndrome in healthy women: antecedent or consequence? Metabolism 2002 51 : 1573 1577.
17. Herva A, Rasanen P, Miettunen J et al. Co-occurrence of metabolic syndrome with depression and anxiety in young adults: the Northern Finland 1966 Birth Cohort Study. Psychosom Med 2006 68 : 213 216. (Pubitemid 43740123)
18. Gil K, Radzillowicz P, Zdrojewski T et al. Relationship between the prevalence of depressive symptoms and metabolic syndrome. Results of the SOPKARD Project. Kardiol Pol 2006 64 : 464 469.
19. Heiskanen TH, Niskanen LK, Hintikka JJ et al. Metabolic syndrome and depression: a cross-sectional analysis. J Clin Psychiatry 2006 67 : 1422 1427.
20. Miettola J, Niskanen LK, Viinamaki H, Kumpusalo E. Metabolic syndrome is associated with self-perceived depression. Scand J Prim Health Care 2008 26 : 203 210.
21. Vaccarino V, Mcclure C, Johnson BD et al. Depression, the metabolic syndrome and cardiovascular risk. Psychosom Med 2008 70 : 40 48.
22. Vogelzangs N, Beekman AT, Kritchevsky SB et al. Psychosocial risk factors and the metabolic syndrome in elderly persons: findings from the Health, Aging and Body Composition study. J Gerontol A Biol Sci Med Sci 2007 62 : 563 569.
23. Roriz-Cruz M, Rosset I, Wada T et al. Stroke-independent association between metabolic syndrome and functional dependence, depression, and low quality of life in elderly community-dwelling Brazilian people. J Am Geriatr Soc 2007 55 : 374 382.
24. Goldbacher EM, Bromberger J, Matthews KA. Lifetime history of major depression predicts the development of the metabolic syndrome in middle-aged women. Psychosom Med 2009 71 : 266 272.
25. Muhtz C, Zyriax BC, Klahn T, Windler E, Otte C. Depressive symptoms and metabolic risk: effects of cortisol and gender. Psychoneuroendocrinology 2009 34 : 1004 1011.
26. Laudisio A, Marzetti E, Pagano F, Pozzi G, Bernabei R, Zuccala G. Depressive symptoms and metabolic syndrome: selective association in older women. J Geriatr Psychiatry Neurol 2009 22 : 215 222.
27. Hildrum B, Mykletun A, Midthjell K, Ismail K, Dahl AA. No association of depression and anxiety with the metabolic syndrome: the Norwegian HUNT study. Acta Psychiatr Scand 2009 120 : 14 22.
28. Viinamaki H, Heiskanen T, Lehto SM et al. Association of depressive symptoms and metabolic syndrome in men. Acta Psychiatr Scand 2009 120 : 23 29.
29. Carroll D, Phillips AC, Thomas GN, Gale CR, Deary I, Batty GD. Generalized anxiety disorder is associated with metabolic syndrome in the Vietnam experience study. Biol Psychiatry 2009 66 : 91 93.
30. Richter N, Juckel G, Assion HJ. Metabolic syndrome: a follow-up study of acute depressive inpatients. Eur Arch Psychiatry Clin Neurosci 2010 260 : 41 49.
31. Lehto SM, Hintikka J, Niskanen L et al. Low HDL cholesterol associates with major depression in a sample with a 7-year history of depressive symptoms. Prog Neuropsychopharmacol Biol Psychiatry 2008 32 : 1557 1561.
32. Licht CM, De Geus EJ, Seldenrijk A et al. Depression is associated with decreased blood pressure, but antidepressant use increases the risk for hypertension. Hypertension 2009 53 : 631 638.
33. Mcintyre RS, Soczynska JK, Konarski JZ, Kennedy SH. The effect of antidepressants on glucose homeostasis and insulin sensitivity: synthesis and mechanisms. Expert Opin Drug Saf 2006 5 : 157 168.
34. Mann JJ. The medical management of depression. N Engl J Med 2005 353 : 1819 1834.
35. Fava M. Weight gain and antidepressants. J Clin Psychiatry 2000 61 (Suppl. 11 37 41.
36. Mcintyre RS, Soczynska JK, Konarski JZ, Kennedy SH. The effect of antidepressants on lipid homeostasis: a cardiac safety concern? Expert Opin Drug Saf 2006 5 : 523 537.
37. Penninx BW, Beekman AT, Smit JH et al. The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods. Int J Methods Psychiatr Res 2008 17 : 121 140.
38. World Health Organisation (WHO). The Composite International Diagnostic Interview (CIDI).
39. Kabacoff RI, Segal DL, Hersen M, Van Hasselt VB. Psychometric properties and diagnostic utility of the Beck Anxiety Inventory and the State-Trait Anxiety Inventory with older adult psychiatric outpatients. J Anxiety Disord 1997 11 : 33 47.
40. IDS. IDS guide. Available from: http://www.ids-qids.org/. 2008.
41. WHO. WHO Collaborating Centre for Drug Statistics Methodology. Available from: http://www.whocc.no/. 2008.
42. Yaffe K, Kanaya A, Lindquist K et al. The metabolic syndrome, inflammation, and risk of cognitive decline. JAMA 2004 292 : 2237 2242.
43. Booth M. Assessment of physical activity: an international perspective. Res Q Exerc Sport 2000 71 : S114 S120.
44. De Graaf R, Bijl RV, Ten Have M, Beekman AT, Vollebergh WA. Pathways to comorbidity: the transition of pure mood, anxiety and substance use disorders into comorbid conditions in a longitudinal population-based study. J Affect Disord 2004 82 : 461 467.
45. De Graaf R, Bijl RV, Ten Have M, Beekman AT, Vollebergh WA. Rapid onset of comorbidity of common mental disorders: findings from the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Acta Psychiatr Scand 2004 109 : 55 63.
46. Meigs JB, D'agostino RB Sr., Wilson PW, Cupples LA, Nathan DM, Singer DE. Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study. Diabetes 1997 46 : 1594 1600.
47. Kahn R, Buse J, Ferrannini E, Stern M. The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2005 28 : 2289 2304. (Pubitemid 41242486)
48. Van Reedt Dortland AKB, Giltay EJ, Van Veen T, Van Pelt J, Zitman FG Serum lipids and major depressive disorder: results from the NESDA cohort study. J Clin Psychiatry 2009. December 19. [Epub ahead of print].
49. Bonnet F, Irving K, Terra JL, Nony P, Berthezene F, Moulin P. Anxiety and depression are associated with unhealthy lifestyle in patients at risk of cardiovascular disease. Atherosclerosis 2005 178 : 339 344.
50. Yirmiya R, Pollak Y, Morag M et al. Illness, cytokines, and depression. Ann N Y Acad Sci 2000 917 : 478 487.
51. Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 2000 23 : 477 501.
52. Bjorntorp P, Rosmond R. The metabolic syndrome - a neuroendocrine disorder? Br J Nutr 2000 83 (Suppl. 1 S49 S57.
53. Maes M, Bosmans E, Suy E, Vandervorst C, Dejonckheere C, Raus J. Depression-related disturbances in mitogen-induced lymphocyte responses and interleukin-1 beta and soluble interleukin-2 receptor production. Acta Psychiatr Scand 1991 84 : 379 386.
54. Penninx BW, Kritchevsky SB, Yaffe K et al. Inflammatory markers and depressed mood in older persons: results from the health, aging and body composition study. Biol Psychiatry 2003 54 : 566 572.
55. Lehto SM, Huotari A, Niskanen L et al. Serum adiponectin and resistin levels in major depressive disorder. Acta Psychiatr Scand 2010 121 : 209 215.
56. Brunner EJ, Hemingway H, Walker BR et al. Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study. Circulation 2002 106 : 2659 2665.
57. Mezzacappa E, Steingard R, Kindlon D, Saul JP, Earls F. Tricyclic antidepressants and cardiac autonomic control in children and adolescents. J Am Acad Child Adolesc Psychiatry 1998 37 : 52 59.