-
1
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956;11:298-300.
-
(1956)
J Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
2
-
-
28944439010
-
Dietary fiber intake and risk of colorectal cancer: A pooled analysis of prospective cohort studies
-
DOI 10.1001/jama.294.22.2849
-
Park Y, Hunter DJ, Spiegelman D, Bergkvist L, Berrino F, van den Brandt PA, et al. Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies. JAMA. 2005;294:2849-57. (Pubitemid 41785865)
-
(2005)
Journal of the American Medical Association
, vol.294
, Issue.22
, pp. 2849-2857
-
-
Park, Y.1
Hunter, D.J.2
Spiegelman, D.3
Bergkvist, L.4
Berrino, F.5
Van Den Brandt, P.A.6
Buring, J.E.7
Colditz, G.A.8
Freudenheim, J.L.9
Fuchs, C.S.10
Giovannucci, E.11
Goldbohm, R.A.12
Graham, S.13
Harnack, L.14
Hartman, A.M.15
Jacobs Jr., D.R.16
Kato, I.17
Krogh, V.18
Leitzmann, M.F.19
McCullough, M.L.20
Miller, A.B.21
Pietinen, P.22
Rohan, T.E.23
Schatzkin, A.24
Willett, W.C.25
Wolk, A.26
Zeleniuch-Jacquotte, A.27
Zhang, S.M.28
Smith-Warner, S.A.29
more..
-
3
-
-
77954973280
-
Efficacy of antioxidant vitamins and selenium supplement in prostate cancer prevention: A meta-analysis of randomized controlled trials
-
Jiang L, Yang KH, Tian JH, Guan QL, Yao N, Cao N, et al. Efficacy of antioxidant vitamins and selenium supplement in prostate cancer prevention: a meta-analysis of randomized controlled trials. Nutr Cancer. 2010;62:719-27.
-
(2010)
Nutr Cancer.
, vol.62
, pp. 719-727
-
-
Jiang, L.1
Yang, K.H.2
Tian, J.H.3
Guan, Q.L.4
Yao, N.5
Cao, N.6
-
4
-
-
33847378451
-
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
-
DOI 10.1001/jama.297.8.842
-
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and metaanalysis. JAMA. 2007;297:842-57. (Pubitemid 46333949)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.8
, pp. 842-857
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
6
-
-
34748850786
-
Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress
-
DOI 10.1016/j.cmet.2007.08.011, PII S1550413107002562
-
Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab. 2007;6:280-93. (Pubitemid 47468090)
-
(2007)
Cell Metabolism
, vol.6
, Issue.4
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
7
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science. 2009;325:201-4.
-
(2009)
Science
, vol.325
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
Kastman, E.K.4
Kosmatka, K.J.5
Beasley, T.M.6
-
8
-
-
66649109663
-
Antioxidants prevent health-promoting effects of physical exercise in humans
-
Ristow M, Zarse K, Oberbach A, Klöting N, Birringer M, Kiehntopf M, et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Nat Acad Sci. 2009;106:8665-70.
-
(2009)
Proc Nat Acad Sci.
, vol.106
, pp. 8665-8670
-
-
Ristow, M.1
Zarse, K.2
Oberbach, A.3
Klöting, N.4
Birringer, M.5
Kiehntopf, M.6
-
9
-
-
31144462150
-
Nutrition, hormetic stress and health
-
DOI 10.1079/NRR2005110
-
Lindsay DG. Nutrition, hormetic stress and health. Nutr Res Rev. 2005;18:249-58. (Pubitemid 43132206)
-
(2005)
Nutrition Research Reviews
, vol.18
, Issue.2
, pp. 249-258
-
-
Lindsay, D.G.1
-
10
-
-
77949908145
-
Hormesis is central to toxicology, pharmacology and risk assessment
-
Calabrese EJ. Hormesis is central to toxicology, pharmacology and risk assessment. Hum Exp Toxicol. 2010;29:249-61.
-
(2010)
Hum Exp Toxicol.
, vol.29
, pp. 249-261
-
-
Calabrese, E.J.1
-
11
-
-
77952548782
-
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
-
Ristowand M, Zarse K. How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). Exp Gerontol. 2010;45:410-8.
-
(2010)
Exp Gerontol.
, vol.45
, pp. 410-418
-
-
Ristowand, M.1
Zarse, K.2
-
12
-
-
78649467294
-
Nutraceutical antioxidants as novel neuroprotective agents
-
Kelsey NA, WilkinsHM, Linseman DA. Nutraceutical antioxidants as novel neuroprotective agents. Molecules. 2010;15:7792-814.
-
(2010)
Molecules.
, vol.15
, pp. 7792-7814
-
-
Kelsey, N.A.1
Wilkins, H.M.2
Linseman, D.A.3
-
13
-
-
79954504166
-
Basic principles and emerging concepts in the redox control of transcription factors
-
doi:10.1089/ars.2010.3534
-
Brigelius-Flohe R, Flohe L. Basic principles and emerging concepts in the redox control of transcription factors. Antioxid Redox Signal. (2011); doi:10.1089/ars.2010.3534.
-
(2011)
Antioxid Redox Signal.
-
-
Brigelius-Flohe, R.1
Flohe, L.2
-
16
-
-
0000000661
-
Effects of extract of western redcedar heartwood on certain wood-decaying fungi in culture
-
Southamand CM, Ehrlich J. Effects of extract of western redcedar heartwood on certain wood-decaying fungi in culture. Phytopathology. 1943;33:517-24.
-
(1943)
Phytopathology.
, vol.33
, pp. 517-524
-
-
Southamand, C.M.1
Ehrlich, J.2
-
18
-
-
0034575085
-
Longevity and aging: Beneficial effects of exposure to mild stress
-
Minois N. Longevity and aging: beneficial effects of exposure to mild stress. Biogerontology. 2000;1:15-29.
-
(2000)
Biogerontology
, vol.1
, pp. 15-29
-
-
Minois, N.1
-
19
-
-
0033794769
-
Hormesis: A stress response in cells exposed to low levels of heavy metals
-
Damelin LH, Vokes S, Whitcutt JM, Damelin SB, Alexander JJ. Hormesis: a stress response in cells exposed to low levels of heavy metals. Hum Exp Toxicol. 2000;19:420-30.
-
(2000)
Hum Exp Toxicol.
, vol.19
, pp. 420-430
-
-
Damelin, L.H.1
Vokes, S.2
Whitcutt, J.M.3
Damelin, S.B.4
Alexander, J.J.5
-
20
-
-
31844439407
-
Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients: "Mitohormesis" for health and vitality
-
DOI 10.1016/j.mehy.2005.09.009, PII S0306987705004676
-
Tapia PC. Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients: 'Mitohormesis' for health and vitality. Med Hypotheses. 2006;66:832-43. (Pubitemid 43181634)
-
(2006)
Medical Hypotheses
, vol.66
, Issue.4
, pp. 832-843
-
-
Tapia, P.C.1
-
21
-
-
78649636576
-
Dietary isoflavones and vascular protection: Activation of cellular antioxidant defenses by SERMs or hormesis?
-
Siowand RC, Mann GE. Dietary isoflavones and vascular protection: activation of cellular antioxidant defenses by SERMs or hormesis? Mol Aspects Med. 2010;31:468-77.
-
(2010)
Mol Aspects Med.
, vol.31
, pp. 468-477
-
-
Siowand, R.C.1
Mann, G.E.2
-
22
-
-
77950268110
-
The hormetic role of dietary antioxidants in free radical-related diseases
-
Calabrese V, Cornelius C, Trovato A, Cavallaro M, Mancuso C, Di Rienzo L, et al. The hormetic role of dietary antioxidants in free radical-related diseases. Curr Pharm Des. 2010;16:877-83.
-
(2010)
Curr Pharm Des.
, vol.16
, pp. 877-883
-
-
Calabrese, V.1
Cornelius, C.2
Trovato, A.3
Cavallaro, M.4
Mancuso, C.5
Di Rienzo, L.6
-
23
-
-
28844493577
-
Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence
-
DOI 10.1016/j.febslet.2005.11.017, PII S0014579305013773
-
Kharade SV, Mittal N, Das SP, Sinha P, Roy N. Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence. FEBS Lett. 2005;579:6809-13. (Pubitemid 41773691)
-
(2005)
FEBS Letters
, vol.579
, Issue.30
, pp. 6809-6813
-
-
Kharade, S.V.1
Mittal, N.2
Das, S.P.3
Sinha, P.4
Roy, N.5
-
24
-
-
0000853087
-
Prolongation of the life of Drosophila subobscura by a brief exposure of adults to a high temperature
-
Smith JM. Prolongation of the life of Drosophila subobscura by a brief exposure of adults to a high temperature. Nature. 1958;181:496-7.
-
(1958)
Nature
, vol.181
, pp. 496-497
-
-
Smith, J.M.1
-
25
-
-
33751542902
-
Hormesis and aging in Caenorhabditis elegans
-
DOI 10.1016/j.exger.2006.09.004, PII S053155650600283X
-
Cypser JR, Tedesco P, Johnson TE. Hormesis and aging in Caenorhabditis elegans. Exp Gerontol. 2006;41:935-9. (Pubitemid 44830104)
-
(2006)
Experimental Gerontology
, vol.41
, Issue.10
, pp. 935-939
-
-
Cypser, J.R.1
Tedesco, P.2
Johnson, T.E.3
-
26
-
-
0031669208
-
Effect of a continuous gamma irradiation at a very low dose on the life span of mice
-
Caratero A, Courtade M, Bonnet L, Planel H, Caratero C. Effect of a continuous gamma irradiation at a very low dose on the life span of mice. Gerontology. 1998;44:272-6. (Pubitemid 28403388)
-
(1998)
Gerontology
, vol.44
, Issue.5
, pp. 272-276
-
-
Caratero, A.1
Courtade, M.2
Bonnet, L.3
Planel, H.4
Caratero, C.5
-
27
-
-
39749104169
-
Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint
-
DOI 10.1038/ng.2007.50, PII NG200750
-
Owusu-Ansah E, Yavari A, Mandal S, Banerjee U. Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint. Nat Genet. 2008;40:356-61. (Pubitemid 351311760)
-
(2008)
Nature Genetics
, vol.40
, Issue.3
, pp. 356-361
-
-
Owusu-Ansah, E.1
Yavari, A.2
Mandal, S.3
Banerjee, U.4
-
28
-
-
70349512259
-
Reactive oxygen species enhance insulin sensitivity
-
Loh K, Deng H, Fukushima A, Cai X, Boivin B, Galic S, et al. Reactive oxygen species enhance insulin sensitivity. Cell Metab. 2009;10:260-72.
-
(2009)
Cell Metab.
, vol.10
, pp. 260-272
-
-
Loh, K.1
Deng, H.2
Fukushima, A.3
Cai, X.4
Boivin, B.5
Galic, S.6
-
29
-
-
0344915418
-
Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis
-
Talalay P, De Long MJ, Prochaska HJ. Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis. Proc Natl Acad Sci USA. 1988;85:8261-5.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8261-8265
-
-
Talalay, P.1
De Long, M.J.2
Prochaska, H.J.3
-
30
-
-
0038378322
-
Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis
-
DOI 10.1016/S0065-2571(02)00038-9
-
Talalay P, Dinkova-Kostova AT, Holtzclaw WD. Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis. Adv Enzyme Regul. 2003;43:121-34. (Pubitemid 36872827)
-
(2003)
Advances in Enzyme Regulation
, vol.43
, pp. 121-134
-
-
Talalay, P.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
-
31
-
-
56249106571
-
Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals
-
Surh YJ, Kundu JK, Na HK. Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Med. 2008;74:1526-39.
-
(2008)
Planta Med.
, vol.74
, pp. 1526-1539
-
-
Surh, Y.J.1
Kundu, J.K.2
Na, H.K.3
-
32
-
-
78149434112
-
The Nrf2 system as a potential target for the development of indirect antioxidants
-
Jungand KA, Kwak MK. The Nrf2 system as a potential target for the development of indirect antioxidants. Molecules. 2010;15:7266-91.
-
(2010)
Molecules.
, vol.15
, pp. 7266-7291
-
-
Jungand, K.A.1
Kwak, M.K.2
-
34
-
-
33747728194
-
Dimerization of substrate adaptors can facilitate Cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: A two-site interaction model for the Nrf2-Keap1 complex
-
DOI 10.1074/jbc.M601119200
-
McMahon M, Thomas N, Itoh K, Yamamoto M, Hayes JD. Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex. J Biol Chem. 2006;281:24756-68. (Pubitemid 44274250)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.34
, pp. 24756-24768
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
35
-
-
22544464124
-
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
-
DOI 10.1073/pnas.0502402102
-
Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc Natl Acad Sci USA. 2005;102:10070-5. (Pubitemid 41023327)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.29
, pp. 10070-10075
-
-
Eggler, A.L.1
Liu, G.2
Pezzuto, J.M.3
Van Breemen, R.B.4
Mesecar, A.D.5
-
36
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers
-
DOI 10.1073/pnas.0307301101
-
Wakabayashi N, Dinkova-Kostova AT, Holtzclaw WD, Kang MI, Kobayashi A, Yamamoto M, et al. Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers. Proc Natl Acad Sci USA. 2004;101:2040-5. (Pubitemid 38229011)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.7
, pp. 2040-2045
-
-
Wakabayashi, N.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
Kang, M.-I.4
Kobayashi, A.5
Yamamoto, M.6
Kensler, T.W.7
Talalay, P.8
-
37
-
-
78651099584
-
Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning
-
author reply E3-4
-
Bell KF, Al-Mubarak B, Fowler JH, Baxter PS, Gupta K, Tsujita T, et al. Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning. Proc Natl Acad Sci USA. 2011;108:E1-2. author reply E3-4.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
-
-
Bell, K.F.1
Al-Mubarak, B.2
Fowler, J.H.3
Baxter, P.S.4
Gupta, K.5
Tsujita, T.6
-
38
-
-
78049233238
-
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway
-
Haskew-Layton RE, Payappilly JB, Smirnova NA, Ma TC, Chan KK, Murphy TH, et al. Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway. Proc Natl Acad Sci USA. 2010;107:17385-90.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 17385-17390
-
-
Haskew-Layton, R.E.1
Payappilly, J.B.2
Smirnova, N.A.3
Ma, T.C.4
Chan, K.K.5
Murphy, T.H.6
-
39
-
-
78649919277
-
Resveratrol: An assessment of its dose response an introduction
-
Calabrese EJ. Resveratrol: an assessment of its dose response an introduction. Hum Exp Toxicol. 2010;29:977-9.
-
(2010)
Hum Exp Toxicol.
, vol.29
, pp. 977-979
-
-
Calabrese, E.J.1
-
40
-
-
78650763353
-
Intracellular GSH depletion triggered mitochondrial Bax translocation to accomplish resveratrolinduced apoptosis in the U937 cell line
-
Guha P, Dey A, Sen R, Chatterjee M, Chattopadhyay S, Bandyopadhyay SK. Intracellular GSH depletion triggered mitochondrial Bax translocation to accomplish resveratrolinduced apoptosis in the U937 cell line. J Pharmacol Exp Ther. 2011;336:206-14.
-
(2011)
J Pharmacol Exp Ther.
, vol.336
, pp. 206-214
-
-
Guha, P.1
Dey, A.2
Sen, R.3
Chatterjee, M.4
Chattopadhyay, S.5
Bandyopadhyay, S.K.6
-
41
-
-
84855751379
-
Resveratrol protects quail hepatocytes against heat stress: Modulation of the Nrf2 transcription factor and heat shock proteins
-
doi:10.1111/j.1439-0396.2010.01123.x
-
Sahin K, Orhan C, Akdemir F, Tuzcu M, Iben C, Sahin N. Resveratrol protects quail hepatocytes against heat stress: modulation of the Nrf2 transcription factor and heat shock proteins. J Anim Physiol Anim Nutr (Berl). 2011; doi:10.1111/j.1439-0396.2010.01123.x.
-
(2011)
J Anim Physiol Anim Nutr (Berl).
-
-
Sahin, K.1
Orhan, C.2
Akdemir, F.3
Tuzcu, M.4
Iben, C.5
Sahin, N.6
-
42
-
-
23844553151
-
Xanthohumol isolated from Humulus lupulus inhibits menadione-induced DNA damage through induction of quinone reductase
-
DOI 10.1021/tx050058x
-
Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, et al. Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase. Chem Res Toxicol. 2005;18:1296-305. (Pubitemid 41170254)
-
(2005)
Chemical Research in Toxicology
, vol.18
, Issue.8
, pp. 1296-1305
-
-
Dietz, B.M.1
Kang, Y.-H.2
Liu, G.3
Eggler, A.L.4
Yao, P.5
Chadwick, L.R.6
Pauli, G.F.7
Farnsworth, N.R.8
Mesecar, A.D.9
Van Breemen, R.B.10
Bolton, J.L.11
-
43
-
-
70349801984
-
Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta (12, 14)-prostaglandin J(2)
-
Kansanen E, Kivela AM, Levonen AL. Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta(12,14)-prostaglandin J(2). Free Radic Biol Med. 2009;47:1310-7.
-
(2009)
Free Radic Biol Med.
, vol.47
, pp. 1310-1317
-
-
Kansanen, E.1
Kivela, A.M.2
Levonen, A.L.3
-
44
-
-
36349020163
-
Sites of alkylation of human keap1 by natural chemoprevention agents
-
DOI 10.1016/j.jasms.2007.09.015, PII S1044030507008483
-
Luo Y, Eggler AL, Liu D, Liu G, Mesecar AD, van Breemen RB. Sites of alkylation of human Keap1 by natural chemoprevention agents. J Am Soc Mass Spectrom. 2007;18:2226-32. (Pubitemid 350161332)
-
(2007)
Journal of the American Society for Mass Spectrometry
, vol.18
, Issue.12
, pp. 2226-2232
-
-
Luo, Y.1
Eggler, A.L.2
Liu, D.3
Liu, G.4
Mesecar, A.D.5
Van Breemen, R.B.6
-
45
-
-
64549130036
-
Fragrant unsaturated aldehydes elicit activation of the Keap1/Nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress
-
Masutani H, Otsuki R, Yamaguchi Y, Takenaka M, Kanoh N, Takatera K, et al. Fragrant unsaturated aldehydes elicit activation of the Keap1/Nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress. Antioxid Redox Signal. 2009;11:949-62.
-
(2009)
Antioxid Redox Signal.
, vol.11
, pp. 949-962
-
-
Masutani, H.1
Otsuki, R.2
Yamaguchi, Y.3
Takenaka, M.4
Kanoh, N.5
Takatera, K.6
-
46
-
-
33244472848
-
Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo
-
DOI 10.1021/ja057358l
-
Fangand J, Holmgren A. Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo. J Am Chem Soc. 2006;128:1879-85. (Pubitemid 43277327)
-
(2006)
Journal of the American Chemical Society
, vol.128
, Issue.6
, pp. 1879-1885
-
-
Fang, J.1
Holmgren, A.2
-
47
-
-
0037379388
-
Molecular basis of enzyme inactivation by an endogenous electrophile 4-hydroxy-2-nonenal: Identification of modification sites in glyceraldehyde-3-phosphate dehydrogenase
-
DOI 10.1021/bi027172o
-
Ishii T, Tatsuda E, Kumazawa S, Nakayama T, Uchida K. Molecular basis of enzyme inactivation by an endogenous electrophile 4-hydroxy-2-nonenal: identification of modification sites in glyceraldehyde-3-phosphate dehydrogenase. Biochemistry. 2003;42:3474-80. (Pubitemid 36368641)
-
(2003)
Biochemistry
, vol.42
, Issue.12
, pp. 3474-3480
-
-
Ishii, T.1
Tatsuda, E.2
Kumazawa, S.3
Nakayama, T.4
Uchida, K.5
-
48
-
-
0031565995
-
Interactions of α, β-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1
-
DOI 10.1016/S0009-2797(97)00096-3, PII S0009279797000963
-
van Iersel ML, Ploemen JP, Lo Bello M, Federici G, van Bladeren PJ. Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1. Chem Biol Interact. 1997;108:67-78. (Pubitemid 28057494)
-
(1997)
Chemico-Biological Interactions
, vol.108
, Issue.1-2
, pp. 67-78
-
-
Van Iersel, M.L.P.S.1
Ploemen, J.-P.H.T.M.2
Lo Bello, M.3
Federici, G.4
Van Bladeren, P.J.5
-
49
-
-
23244458797
-
Covalent modification of actin by 4-hydroxy-trans-2-nonenal (HNE): LC-ESI-MS/MS evidence for Cys374 Michael adduction
-
DOI 10.1002/jms.872
-
Aldini G, Dalle-Donne I, Vistoli G, Maffei Facino R, Carini M. Covalent modification of actin by 4-hydroxy-trans-2-nonenal (HNE): LC-ESI-MS/MS evidence for Cys374 Michael adduction. J Mass Spectrom. 2005;40:946-54. (Pubitemid 41098081)
-
(2005)
Journal of Mass Spectrometry
, vol.40
, Issue.7
, pp. 946-954
-
-
Aldini, G.1
Dalle-Donne, I.2
Vistoli, G.3
Facino, R.M.4
Carini, M.5
-
50
-
-
77950996693
-
1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes
-
Klaus V, Hartmann T, Gambini J, Graf P, Stahl W, Hartwig A, et al. 1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes. Arch Biochem Biophys. 2010;496:93-100.
-
(2010)
Arch Biochem Biophys.
, vol.496
, pp. 93-100
-
-
Klaus, V.1
Hartmann, T.2
Gambini, J.3
Graf, P.4
Stahl, W.5
Hartwig, A.6
-
51
-
-
55949084077
-
Molecular transduction mechanisms of the redox network underlying the antiproliferative effects of allyl compounds from garlic
-
Filomeni G, Rotilio G, Ciriolo MR. Molecular transduction mechanisms of the redox network underlying the antiproliferative effects of allyl compounds from garlic. J Nutr. 2008;138:2053-7.
-
(2008)
J Nutr.
, vol.138
, pp. 2053-2057
-
-
Filomeni, G.1
Rotilio, G.2
Ciriolo, M.R.3
-
52
-
-
0028898483
-
Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases
-
Zhang Y, Kolm RH, Mannervik B, Talalay P. Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases. Biochem Biophys Res Commun. 1995;206:748-55.
-
(1995)
Biochem Biophys Res Commun.
, vol.206
, pp. 748-755
-
-
Zhang, Y.1
Kolm, R.H.2
Mannervik, B.3
Talalay, P.4
-
53
-
-
77953100764
-
Electrophilic tuning of the chemoprotective natural product sulforaphane
-
Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, et al. Electrophilic tuning of the chemoprotective natural product sulforaphane. Proc Natl Acad Sci USA. 2010;107: 9590-5.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9590-9595
-
-
Ahn, Y.H.1
Hwang, Y.2
Liu, H.3
Wang, X.J.4
Zhang, Y.5
Stephenson, K.K.6
-
54
-
-
70349783629
-
The influence of the branched-chain fatty acids pristanic acid and Refsum diseaseassociated phytanic acid on mitochondrial functions and calcium regulation of hippocampal neurons, astrocytes, and oligodendrocytes
-
Ronicke S, Kruska N, Kahlert S, Reiser G. The influence of the branched-chain fatty acids pristanic acid and Refsum diseaseassociated phytanic acid on mitochondrial functions and calcium regulation of hippocampal neurons, astrocytes, and oligodendrocytes. Neurobiol Dis. 2009;36:401-10.
-
(2009)
Neurobiol Dis.
, vol.36
, pp. 401-410
-
-
Ronicke, S.1
Kruska, N.2
Kahlert, S.3
Reiser, G.4
-
55
-
-
80052241805
-
Proapoptotic effects of long-chain vitamin e metabolites in HepG2 cells are mediated by oxidative stress
-
Birringer M, Lington D, Vertuani S, Manfredini S, Scharlau D, Glei M, et al. Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress. Free Radic Biol Med. 2010;49:1315-22.
-
(2010)
Free Radic Biol Med.
, vol.49
, pp. 1315-1322
-
-
Birringer, M.1
Lington, D.2
Vertuani, S.3
Manfredini, S.4
Scharlau, D.5
Glei, M.6
-
56
-
-
0028892819
-
Crocetin protects against oxidative damage in rat primary hepatocytes
-
Tseng TH, Chu CY, Huang JM, Shiow SJ, Wang CJ. Crocetin protects against oxidative damage in rat primary hepatocytes. Cancer Lett. 1995;97:61-7.
-
(1995)
Cancer Lett.
, vol.97
, pp. 61-67
-
-
Tseng, T.H.1
Chu, C.Y.2
Huang, J.M.3
Shiow, S.J.4
Wang, C.J.5
-
57
-
-
30944448233
-
Acute effect of fatty acids on metabolism and mitochondrial coupling in skeletal muscle
-
DOI 10.1016/j.bbabio.2005.11.007, PII S0005272805002574
-
Hirabara SM, Silveira LR, Alberici LC, Leandro CV, Lambertucci RH, Polimeno GC, et al. Acute effect of fatty acids on metabolism and mitochondrial coupling in skeletal muscle. Biochim Biophys Acta. 2006;1757:57-66. (Pubitemid 43113322)
-
(2006)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1757
, Issue.1
, pp. 57-66
-
-
Hirabara, S.M.1
Silveira, L.R.2
Alberici, L.C.3
Leandro, C.V.G.4
Lambertucci, R.H.5
Polimeno, G.C.6
Cury Boaventura, M.F.7
Procopio, J.8
Vercesi, A.E.9
Curi, R.10
-
58
-
-
77649274855
-
Activation of the Nrf2/ARE pathway via Salkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound
-
Ohnuma T, Nakayama S, Anan E, Nishiyama T, Ogura K, Hiratsuka A. Activation of the Nrf2/ARE pathway via Salkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound. Toxicol Appl Pharmacol. 2010;244:27-36.
-
(2010)
Toxicol Appl Pharmacol.
, vol.244
, pp. 27-36
-
-
Ohnuma, T.1
Nakayama, S.2
Anan, E.3
Nishiyama, T.4
Ogura, K.5
Hiratsuka, A.6
-
59
-
-
62249089498
-
Targeting the redox sensitive Nrf2-Keap1 defense pathway in cardiovascular disease: Protection afforded by dietary isoflavones
-
Mann GE, Bonacasa B, Ishii T, Siow RC. Targeting the redox sensitive Nrf2-Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones. Curr Opin Pharmacol. 2009;9:139-45.
-
(2009)
Curr Opin Pharmacol.
, vol.9
, pp. 139-145
-
-
Mann, G.E.1
Bonacasa, B.2
Ishii, T.3
Siow, R.C.4
-
60
-
-
38449111059
-
Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
-
DOI 10.1111/j.1471-4159.2007.05039.x
-
Satoh T, Kosaka K, Itoh K, Kobayashi A, Yamamoto M, Shimojo Y, et al. Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1. J Neurochem. 2008;104:1116-31. (Pubitemid 351143643)
-
(2008)
Journal of Neurochemistry
, vol.104
, Issue.4
, pp. 1116-1131
-
-
Satoh, T.1
Kosaka, K.2
Itoh, K.3
Kobayashi, A.4
Yamamoto, M.5
Shimojo, Y.6
Kitajima, C.7
Cui, J.8
Kamins, J.9
Okamoto, S.-I.10
Izumi, M.11
Shirasawa, T.12
Lipton, S.A.13
-
61
-
-
58849166492
-
Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neurons
-
Schroeder EK, Kelsey NA, Doyle J, Breed E, Bouchard RJ, Loucks FA, et al. Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neurons. Antioxid Redox Signal. 2009;11:469-80.
-
(2009)
Antioxid Redox Signal.
, vol.11
, pp. 469-480
-
-
Schroeder, E.K.1
Kelsey, N.A.2
Doyle, J.3
Breed, E.4
Bouchard, R.J.5
Loucks, F.A.6
-
62
-
-
31444443311
-
Fruit and vegetable consumption and stroke: Meta-analysis of cohort studies
-
DOI 10.1016/S0140-6736(06)68069-0, PII S0140673606680690
-
He FJ, Nowson CA, MacGregor GA. Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. Lancet. 2006;367:320-6. (Pubitemid 43151465)
-
(2006)
Lancet
, vol.367
, Issue.9507
, pp. 320-326
-
-
He, F.J.1
Nowson, C.A.2
MacGregor, G.A.3
-
63
-
-
33749499884
-
Fruit and vegetable consumption and risk of coronary heart disease: A meta-analysis of cohort studies
-
Dauchet L, Amouyel P, Hercberg S, Dallongeville J. Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. J Nutr. 2006;136:2588-93. (Pubitemid 44521618)
-
(2006)
Journal of Nutrition
, vol.136
, Issue.10
, pp. 2588-2593
-
-
Dauchet, L.1
Amouyel, P.2
Hercberg, S.3
Dallongeville, J.4
-
64
-
-
67449083633
-
Intakes of fruit, vegetables, and carotenoids and renal cell cancer risk: A pooled analysis of 13 prospective studies
-
Lee JE, Mannisto S, Spiegelman D, Hunter DJ, Bernstein L, van den Brandt PA, et al. Intakes of fruit, vegetables, and carotenoids and renal cell cancer risk: a pooled analysis of 13 prospective studies. Cancer Epidemiol Biomarkers Prev. 2009;18:1730-9.
-
(2009)
Cancer Epidemiol Biomarkers Prev.
, vol.18
, pp. 1730-1739
-
-
Lee, J.E.1
Mannisto, S.2
Spiegelman, D.3
Hunter, D.J.4
Bernstein, L.5
Van Den Brandt, P.A.6
-
65
-
-
77956518751
-
Fruit and vegetable intake and incidence of type 2 diabetes mellitus: Systematic review and meta-analysis
-
Carter P, Gray LJ, Troughton J, Khunti K, Davies MJ. Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis. BMJ. 2010;341:c4229.
-
(2010)
BMJ
, vol.341
-
-
Carter, P.1
Gray, L.J.2
Troughton, J.3
Khunti, K.4
Davies, M.J.5
-
66
-
-
79551511123
-
Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - Studies in electrophile response element transgenic mice
-
doi:10.1002/mnfr.201000204
-
Balstad TR, Carlsen H, Myhrstad MC, Kolberg M, Reiersen H, Gilen L, et al. Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - Studies in electrophile response element transgenic mice. Mol Nutr Food Res. 2011; 55(2):185-97. doi:10.1002/mnfr.201000204.
-
(2011)
Mol Nutr Food Res.
, vol.55
, Issue.2
, pp. 185-197
-
-
Balstad, T.R.1
Carlsen, H.2
Myhrstad, M.C.3
Kolberg, M.4
Reiersen, H.5
Gilen, L.6
-
68
-
-
61349117533
-
Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species
-
Reisman SA, Yeager RL, Yamamoto M, Klaassen CD. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species. Toxicol Sci. 2009;108:35-47.
-
(2009)
Toxicol Sci.
, vol.108
, pp. 35-47
-
-
Reisman, S.A.1
Yeager, R.L.2
Yamamoto, M.3
Klaassen, C.D.4
-
69
-
-
0037016759
-
Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells
-
DOI 10.1074/jbc.M109380200
-
Li J, Lee JM, Johnson JA. Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells. J Biol Chem. 2002;277:388-94. (Pubitemid 34952070)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.1
, pp. 388-394
-
-
Li, J.1
Lee, J.-M.2
Johnson, J.A.3
-
70
-
-
58049088157
-
Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element
-
Chowdhury I, Mo Y, Gao L, Kazi A, Fisher AB, Feinstein SI. Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element. Free Radic Biol Med. 2009;46:146-53.
-
(2009)
Free Radic Biol Med.
, vol.46
, pp. 146-153
-
-
Chowdhury, I.1
Mo, Y.2
Gao, L.3
Kazi, A.4
Fisher, A.B.5
Feinstein, S.I.6
-
71
-
-
70249138697
-
Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: Demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds
-
MacLeod AK, McMahon M, Plummer SM, Higgins LG, Penning TM, Igarashi K, et al. Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds. Carcinogenesis. 2009;30:1571-80.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1571-1580
-
-
MacLeod, A.K.1
McMahon, M.2
Plummer, S.M.3
Higgins, L.G.4
Penning, T.M.5
Igarashi, K.6
-
72
-
-
38749090899
-
Regulation of sulfotransferase enzymes by prototypical microsomal enzyme inducers in mice
-
DOI 10.1124/jpet.107.129650
-
Alnoutiand Y, Klaassen CD. Regulation of sulfotransferase enzymes by prototypical microsomal enzyme inducers in mice. J Pharmacol Exp Ther. 2008;324:612-21. (Pubitemid 351185863)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.324
, Issue.2
, pp. 612-621
-
-
Alnouti, Y.1
Klaassen, C.D.2
-
73
-
-
78349302551
-
Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways
-
Zhou P, Gross S, Liu JH, Yu BY, Feng LL, Nolta J, et al. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways. FASEB J. 2010;24:4722-32.
-
(2010)
FASEB J.
, vol.24
, pp. 4722-4732
-
-
Zhou, P.1
Gross, S.2
Liu, J.H.3
Yu, B.Y.4
Feng, L.L.5
Nolta, J.6
-
74
-
-
77953534370
-
A novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells
-
Kuo YF, Su YZ, Tseng YH, Wang SY, Wang HM, Chueh PJ. Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells. Free Radic Biol Med. 2010;49:214-26.
-
(2010)
Free Radic Biol Med.
, vol.49
, pp. 214-226
-
-
Kuo, Y.F.1
Su, Y.Z.2
Tseng, Y.H.3
Wang, S.Y.4
Wang, H.M.5
Chueh, P.J.6
Flavokawain, B.7
-
75
-
-
0036679809
-
Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics
-
DOI 10.1016/S0300-483X(02)00198-1, PII S0300483X02001981
-
Galati G, Sabzevari O, Wilson JX, O'Brien PJ. Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics. Toxicology. 2002;177:91-104. (Pubitemid 34786247)
-
(2002)
Toxicology
, vol.177
, Issue.1
, pp. 91-104
-
-
Galati, G.1
Sabzevari, O.2
Wilson, J.X.3
O'Brien, P.J.4
-
76
-
-
77955050631
-
Caffeic acid phenethyl ester-mediated Nrf2 activation and IkappaB kinase inhibition are involved in NFkappaB inhibitory effect: Structural analysis for NFkappaB inhibition
-
Lee Y, Shin DH, Kim JH, Hong S, Choi D, Kim YJ, et al. Caffeic acid phenethyl ester-mediated Nrf2 activation and IkappaB kinase inhibition are involved in NFkappaB inhibitory effect: structural analysis for NFkappaB inhibition. Eur J Pharmacol. 2010;643:21-8.
-
(2010)
Eur J Pharmacol.
, vol.643
, pp. 21-28
-
-
Lee, Y.1
Shin, D.H.2
Kim, J.H.3
Hong, S.4
Choi, D.5
Kim, Y.J.6
-
77
-
-
77956173651
-
Biochemical mechanism of caffeic acid phenylethyl ester (CAPE) selective toxicity towards melanoma cell lines
-
Kudugunti SK, Vad NM, Whiteside AJ, Naik BU, Yusuf MA, Srivenugopal KS, et al. Biochemical mechanism of caffeic acid phenylethyl ester (CAPE) selective toxicity towards melanoma cell lines. Chem Biol Interact. 2010;188:1-14.
-
(2010)
Chem Biol Interact.
, vol.188
, pp. 1-14
-
-
Kudugunti, S.K.1
Vad, N.M.2
Whiteside, A.J.3
Naik, B.U.4
Yusuf, M.A.5
Srivenugopal, K.S.6
-
78
-
-
49349104835
-
Caffeic acid phenethyl ester preferentially enhanced radiosensitizing and increased oxidative stress in medulloblastoma cell line
-
Lee YY, Kao CL, Tsai PH, Tsai TH, Chiou SH, Wu WF, et al. Caffeic acid phenethyl ester preferentially enhanced radiosensitizing and increased oxidative stress in medulloblastoma cell line. Childs Nerv Syst. 2008;24:987-94.
-
(2008)
Childs Nerv Syst.
, vol.24
, pp. 987-994
-
-
Lee, Y.Y.1
Kao, C.L.2
Tsai, P.H.3
Tsai, T.H.4
Chiou, S.H.5
Wu, W.F.6
-
79
-
-
54349099181
-
Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells
-
Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S. Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells. Free Radic Biol Med. 2008;45:1403-12.
-
(2008)
Free Radic Biol Med.
, vol.45
, pp. 1403-1412
-
-
Thayyullathil, F.1
Chathoth, S.2
Hago, A.3
Patel, M.4
Galadari, S.5
-
80
-
-
67649670106
-
Curcumin upregulates transcription factor Nrf2 HO-1 expression and protects rat brains against focal ischemia
-
Yang C, Zhang X, Fan H, Liu Y. Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Brain Res. 2009;1282:133-41.
-
(2009)
Brain Res.
, vol.1282
, pp. 133-141
-
-
Yang, C.1
Zhang, X.2
Fan, H.3
Liu, Y.4
-
81
-
-
40949089329
-
Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis
-
Hail Jr N. Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis. Free Radic Biol Med. 2008;44:1382-93.
-
(2008)
Free Radic Biol Med.
, vol.44
, pp. 1382-1393
-
-
Hail Jr., N.1
-
82
-
-
34547666803
-
Piperine protects cisplatin-induced apoptosis via heme oxygenase-1 induction in auditory cells
-
DOI 10.1016/j.jnutbio.2006.11.012, PII S0955286307000058
-
Choi BM, Kim SM, Park TK, Li G, Hong SJ, Park R, et al. Piperine protects cisplatin-induced apoptosis via heme oxygenase-1 induction in auditory cells. J Nutr Biochem. 2007;18:615-22. (Pubitemid 47212712)
-
(2007)
Journal of Nutritional Biochemistry
, vol.18
, Issue.9
, pp. 615-622
-
-
Choi, B.-M.1
Kim, S.-M.2
Park, T.-K.3
Li, G.4
Hong, S.-J.5
Park, R.6
Chung, H.-T.7
Kim, B.-R.8
-
83
-
-
48649093632
-
6- Shogaol induces apoptosis in human colorectal carcinoma cells via ROS production, caspase activation, and GADD 153 expression
-
Pan MH, Hsieh MC, Kuo JM, Lai CS, Wu H, Sang S, et al. 6- Shogaol induces apoptosis in human colorectal carcinoma cells via ROS production, caspase activation, and GADD 153 expression. Mol Nutr Food Res. 2008;52:527-37.
-
(2008)
Mol Nutr Food Res.
, vol.52
, pp. 527-537
-
-
Pan, M.H.1
Hsieh, M.C.2
Kuo, J.M.3
Lai, C.S.4
Wu, H.5
Sang, S.6
-
84
-
-
4143081630
-
Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes
-
DOI 10.1016/j.febslet.2004.07.042, PII S0014579304009068
-
Nakamura Y, Yoshida C, Murakami A, Ohigashi H, Osawa T, Uchida K. Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. FEBS Lett. 2004;572:245-50. (Pubitemid 39092543)
-
(2004)
FEBS Letters
, vol.572
, Issue.1-3
, pp. 245-250
-
-
Nakamura, Y.1
Yoshida, C.2
Murakami, A.3
Ohigashi, H.4
Osawa, T.5
Uchida, K.6
-
85
-
-
69249083578
-
Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species
-
Yodkeeree S, Sung B, Limtrakul P, Aggarwal BB. Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species. Cancer Res. 2009;69:6581-9.
-
(2009)
Cancer Res.
, vol.69
, pp. 6581-6589
-
-
Yodkeeree, S.1
Sung, B.2
Limtrakul, P.3
Aggarwal, B.B.4
-
86
-
-
78651259607
-
Antiinflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells
-
Lee IS, Lim J, Gal J, Kang JC, Kim HJ, Kang BY, et al. Antiinflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells. Neurochem Int. 2011;58:153-60.
-
(2011)
Neurochem Int.
, vol.58
, pp. 153-160
-
-
Lee, I.S.1
Lim, J.2
Gal, J.3
Kang, J.C.4
Kim, H.J.5
Kang, B.Y.6
-
87
-
-
77955839687
-
Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism
-
Strathmann J, Klimo K, Sauer SW, Okun JG, Prehn JH, Gerhauser C. Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism. FASEB J. 2010;24:2938-50.
-
(2010)
FASEB J.
, vol.24
, pp. 2938-2950
-
-
Strathmann, J.1
Klimo, K.2
Sauer, S.W.3
Okun, J.G.4
Prehn, J.H.5
Gerhauser, C.6
-
88
-
-
55949091956
-
15-Deoxy-Delta (12, 14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: Potential roles of Akt and ERK1/2
-
Kim JW, Li MH, Jang JH, Na HK, Song NY, Lee C, et al. 15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2. Biochem Pharmacol. 2008;76:1577-89.
-
(2008)
Biochem Pharmacol.
, vol.76
, pp. 1577-1589
-
-
Kim, J.W.1
Li, M.H.2
Jang, J.H.3
Na, H.K.4
Song, N.Y.5
Lee, C.6
-
89
-
-
33744940306
-
2 through up-regulation of cellular glutathione via different mechanisms
-
DOI 10.1074/jbc.M600260200
-
Chen ZH, Yoshida Y, Saito Y, Sekine A, Noguchi N, Niki E. Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta (12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. J Biol Chem. 2006;281:14440-5. (Pubitemid 43848374)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.20
, pp. 14440-14445
-
-
Chen, Z.-H.1
Yoshida, Y.2
Saito, Y.3
Sekine, A.4
Noguchi, N.5
Niki, E.6
-
90
-
-
17444363390
-
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species
-
Chen YC, Shen SC, Tsai SH. Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. Biochim Biophys Acta. 2005;1743:291-304.
-
(2005)
Biochim Biophys Acta.
, vol.1743
, pp. 291-304
-
-
Chen, Y.C.1
Shen, S.C.2
Tsai, S.H.3
-
91
-
-
75049084688
-
Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat: Role of Nrf2, p53, p38 and phase-II enzymes
-
Tripathiand DN, Jena GB. Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat: Role of Nrf2, p53, p38 and phase-II enzymes. Mutat Res. 2010;696:69-80.
-
(2010)
Mutat Res.
, vol.696
, pp. 69-80
-
-
Tripathiand, D.N.1
Jena, G.B.2
-
92
-
-
13944262936
-
Carotenoids activate the antioxidant response element transcription system
-
Ben-Dor A, Steiner M, Gheber L, Danilenko M, Dubi N, Linnewiel K, et al. Carotenoids activate the antioxidant response element transcription system. Mol Cancer Ther. 2005;4:177-86. (Pubitemid 40268075)
-
(2005)
Molecular Cancer Therapeutics
, vol.4
, Issue.1
, pp. 177-186
-
-
Ben-Dor, A.1
Steiner, M.2
Gheber, L.3
Danilenko, M.4
Dubi, N.5
Linnewiel, K.6
Zick, A.7
Sharoni, Y.8
Levy, J.9
-
93
-
-
0037969283
-
Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells
-
DOI 10.1016/S0304-3835(03)00238-6
-
Ka H, Park HJ, Jung HJ, Choi JW, Cho KS, Ha J, et al. Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells. Cancer Lett. 2003;196:143-52. (Pubitemid 36830893)
-
(2003)
Cancer Letters
, vol.196
, Issue.2
, pp. 143-152
-
-
Ka, H.1
Park, H.-J.2
Jung, H.-J.3
Choi, J.-W.4
Cho, K.-S.5
Ha, J.6
Lee, K.-T.7
-
94
-
-
77952827500
-
The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells
-
Wondrak GT, Villeneuve NF, Lamore SD, Bause AS, Jiang T, Zhang DD. The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. Molecules. 2010;15:3338-55.
-
(2010)
Molecules.
, vol.15
, pp. 3338-3355
-
-
Wondrak, G.T.1
Villeneuve, N.F.2
Lamore, S.D.3
Bause, A.S.4
Jiang, T.5
Zhang, D.D.6
-
95
-
-
77954368172
-
The glutaredoxin/ glutathione system modulates NF-kappaB activity by glutathionylation of p65 in cinnamaldehyde-treated endothelial cells
-
Liao BC, Hsieh CW, Lin YC, Wung BS. The glutaredoxin/ glutathione system modulates NF-kappaB activity by glutathionylation of p65 in cinnamaldehyde- treated endothelial cells. Toxicol Sci. 2010;116:151-63.
-
(2010)
Toxicol Sci.
, vol.116
, pp. 151-163
-
-
Liao, B.C.1
Hsieh, C.W.2
Lin, Y.C.3
Wung, B.S.4
-
96
-
-
29644437160
-
4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2
-
DOI 10.1074/jbc.M508556200
-
Chen ZH, Saito Y, Yoshida Y, Sekine A, Noguchi N, Niki E. 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2. J Biol Chem. 2005;280:41921-7. (Pubitemid 43023161)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.51
, pp. 41921-41927
-
-
Chen, Z.-H.1
Saito, Y.2
Yoshida, Y.3
Sekine, A.4
Noguchi, N.5
Niki, E.6
-
97
-
-
33745986025
-
Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein
-
DOI 10.1016/j.taap.2005.12.013, PII S0041008X0600007X
-
Wu CC, Hsieh CW, Lai PH, Lin JB, Liu YC, Wung BS. Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein. Toxicol Appl Pharmacol. 2006;214:244-52. (Pubitemid 44066441)
-
(2006)
Toxicology and Applied Pharmacology
, vol.214
, Issue.3
, pp. 244-252
-
-
Wu, C.C.1
Hsieh, C.W.2
Lai, P.H.3
Lin, J.B.4
Liu, Y.C.5
Wung, B.S.6
-
98
-
-
79951767414
-
Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells
-
in press
-
Lee SE, Jeong SI, Kim GD, Yang H, Park CS, Jin YH, et al. Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells. Toxicol Lett. 2011; in press.
-
(2011)
Toxicol Lett.
-
-
Lee, S.E.1
Jeong, S.I.2
Kim, G.D.3
Yang, H.4
Park, C.S.5
Jin, Y.H.6
-
99
-
-
77953338484
-
Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis
-
Hartwig K, Heidler T, Moch J, Daniel H, Wenzel U. Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis. Genes Nutr. 2009;4:59-67.
-
(2009)
Genes Nutr.
, vol.4
, pp. 59-67
-
-
Hartwig, K.1
Heidler, T.2
Moch, J.3
Daniel, H.4
Wenzel, U.5
-
100
-
-
78650171632
-
Juglone-induced apoptosis in human gastric cancer SGC-7901 cells via the mitochondrial pathway
-
Ji YB, Qu ZY, Zou X. Juglone-induced apoptosis in human gastric cancer SGC-7901 cells via the mitochondrial pathway. Exp Toxicol Pathol. 2011;63:69-78.
-
(2011)
Exp Toxicol Pathol.
, vol.63
, pp. 69-78
-
-
Ji, Y.B.1
Qu, Z.Y.2
Zou, X.3
-
101
-
-
67349276677
-
Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone
-
Przybysz AJ, Choe KP, Roberts LJ, Strange K. Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone. Mech Ageing Dev. 2009;130:357-69.
-
(2009)
Mech Ageing Dev.
, vol.130
, pp. 357-369
-
-
Przybysz, A.J.1
Choe, K.P.2
Roberts, L.J.3
Strange, K.4
-
102
-
-
33747436183
-
2 trigger apoptosis in human ovarian cancer TYK-nu cells
-
DOI 10.1007/s10495-006-7979-5
-
Shibayama-Imazu T, Sonoda I, Sakairi S, Aiuchi T, Ann WW, Nakajo S, et al. Production of superoxide and dissipation of mitochondrial transmembrane potential by vitamin K2 trigger apoptosis in human ovarian cancer TYK-nu cells. Apoptosis. 2006;11:1535-43. (Pubitemid 44253671)
-
(2006)
Apoptosis
, vol.11
, Issue.9
, pp. 1535-1543
-
-
Shibayama-Imazu, T.1
Sonoda, I.2
Sakairi, S.3
Aiuchi, T.4
Ann, W.-W.5
Nakajo, S.6
Itabe, H.7
Nakaya, K.8
-
103
-
-
75949124394
-
Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia
-
Son TG, Camandola S, Arumugam TV, Cutler RG, Telljohann RS, Mughal MR, et al. Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia. J Neurochem. 2010;112:1316-26.
-
(2010)
J Neurochem.
, vol.112
, pp. 1316-1326
-
-
Son, T.G.1
Camandola, S.2
Arumugam, T.V.3
Cutler, R.G.4
Telljohann, R.S.5
Mughal, M.R.6
-
104
-
-
77958010589
-
Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2
-
Bat-Chen W, Golan T, Peri I, Ludmer Z, Schwartz B. Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2. Nutr Cancer. 2010;62:947-57.
-
(2010)
Nutr Cancer.
, vol.62
, pp. 947-957
-
-
Bat-Chen, W.1
Golan, T.2
Peri, I.3
Ludmer, Z.4
Schwartz, B.5
-
105
-
-
34250721692
-
Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak
-
DOI 10.1158/1535-7163.MCT-06-0754
-
Kim YA, Xiao D, Xiao H, Powolny AA, Lew KL, Reilly ML, et al. Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak. Mol Cancer Ther. 2007;6:1599-609. (Pubitemid 46954027)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.5
, pp. 1599-1609
-
-
Kim, Y.-A.1
Xiao, D.2
Xiao, H.3
Powolny, A.A.4
Lew, K.L.5
Reilly, M.L.6
Zeng, Y.7
Wang, Z.8
Singh, S.V.9
-
106
-
-
79955632661
-
The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation
-
Powolny AA, Singh SV, Melov S, Hubbard A, Fisher AL. The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation. Exp Gerontol. 2011; 46 (6):441-52.
-
(2011)
Exp Gerontol.
, vol.46
, Issue.6
, pp. 441-452
-
-
Powolny, A.A.1
Singh, S.V.2
Melov, S.3
Hubbard, A.4
Fisher, A.L.5
-
107
-
-
26244450392
-
α-Lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells
-
DOI 10.1161/01.ATV.0000183745.37161.6e
-
Ogborne RM, Rushworth SA, O'Connell MA. Alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogenactivated protein kinase in human monocytic cells. Arterioscler Thromb Vasc Biol. 2005;25:2100-5. (Pubitemid 41416307)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.10
, pp. 2100-2105
-
-
Ogborne, R.M.1
Rushworth, S.A.2
O'Connell, M.A.3
-
108
-
-
33845726964
-
Increased ROS generation and p53 activation in α-lipoic acid-induced apoptosis of hepatoma cells
-
DOI 10.1007/s10495-006-0487-9
-
Simbula G, Columbano A, Ledda-Columbano GM, Sanna L, Deidda M, Diana A, et al. Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. Apoptosis. 2007;12:113-23. (Pubitemid 46009508)
-
(2007)
Apoptosis
, vol.12
, Issue.1
, pp. 113-123
-
-
Simbula, G.1
Columbano, A.2
Ledda-Columbano, G.M.3
Sanna, L.4
Deidda, M.5
Diana, A.6
Pibiri, M.7
-
109
-
-
77951480791
-
Sulforaphane and alpha-lipoic acid upregulate the expression of the pi class of glutathione S-transferase through c-jun and Nrf2 activation
-
Lii CK, Liu KL, Cheng YP, Lin AH, Chen HW, Tsai CW. Sulforaphane and alpha-lipoic acid upregulate the expression of the pi class of glutathione S-transferase through c-jun and Nrf2 activation. J Nutr. 2010;140:885-92.
-
(2010)
J Nutr.
, vol.140
, pp. 885-892
-
-
Lii, C.K.1
Liu, K.L.2
Cheng, Y.P.3
Lin, A.H.4
Chen, H.W.5
Tsai, C.W.6
-
110
-
-
77953620909
-
Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme
-
Ping Z, Liu W, Kang Z, Cai J, Wang Q, Cheng N, et al. Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme. Brain Res. 2010;1343:178-85.
-
(2010)
Brain Res.
, vol.1343
, pp. 178-185
-
-
Ping, Z.1
Liu, W.2
Kang, Z.3
Cai, J.4
Wang, Q.5
Cheng, N.6
-
111
-
-
74949124720
-
Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture
-
Wagner AE, Ernst I, Iori R, Desel C, Rimbach G. Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture. Exp Dermatol. 2010;19:137-44.
-
(2010)
Exp Dermatol.
, vol.19
, pp. 137-144
-
-
Wagner, A.E.1
Ernst, I.2
Iori, R.3
Desel, C.4
Rimbach, G.5
-
112
-
-
21244461140
-
Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species
-
DOI 10.1074/jbc.M412443200
-
Singh SV, Srivastava SK, Choi S, Lew KL, Antosiewicz J, Xiao D, et al. Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species. J Biol Chem. 2005;280:19911-24. (Pubitemid 41379520)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.20
, pp. 19911-19924
-
-
Singh, S.V.1
Srivastava, S.K.2
Choi, S.3
Lew, K.L.4
Antosiewicz, J.5
Xiao, D.6
Zeng, Y.7
Watkins, S.C.8
Johnson, C.S.9
Trump, D.L.10
Lee, Y.J.11
Xiao, H.12
Herman-Antosiewicz, A.13
-
113
-
-
67949085219
-
The augmenting activity of 6-(methylsulfinyl)hexyl isothiocyanate on cellular glutathione levels is less sensitive to thiol compounds than its cytotoxic activity
-
Kidachi Y, Noshita T, Yamaguchi H, Umetsu H, Fuke Y, Ryoyama K. The augmenting activity of 6-(methylsulfinyl)hexyl isothiocyanate on cellular glutathione levels is less sensitive to thiol compounds than its cytotoxic activity. Biosci Biotechnol Biochem. 2009;73:1419-21.
-
(2009)
Biosci Biotechnol Biochem.
, vol.73
, pp. 1419-1421
-
-
Kidachi, Y.1
Noshita, T.2
Yamaguchi, H.3
Umetsu, H.4
Fuke, Y.5
Ryoyama, K.6
-
114
-
-
43449083524
-
Detection of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) and its conjugate with N-acetyl-L-cysteine (NAC) by high performance liquid chromatograpy-atmospheric pressure chemical ionization mass spectrometry (HPLC-MS/APCI)
-
DOI 10.1248/cpb.56.715
-
Yamaguchi H, Noshita T, Kidachi Y, Umetsu H, Fuke Y, Ryoyama K. Detection of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) and its conjugate with N-acetyl-L-cysteine (NAC) by high performance liquid chromatograpy-atmospheric pressure chemical ionization mass spectrometry (HPLC-MS/APCI). Chem Pharm Bull (Tokyo). 2008;56:715-9. (Pubitemid 351669444)
-
(2008)
Chemical and Pharmaceutical Bulletin
, vol.56
, Issue.5
, pp. 715-719
-
-
Yamaguchi, H.1
Noshita, T.2
Kidachi, Y.3
Umetsu, H.4
Fuke, Y.5
Ryoyama, K.6
-
115
-
-
0036479330
-
A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway
-
DOI 10.1074/jbc.M110244200
-
Morimitsu Y, Nakagawa Y, Hayashi K, Fujii H, Kumagai T, Nakamura Y, et al. A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway. J Biol Chem. 2002;277:3456-63. (Pubitemid 34953214)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.5
, pp. 3456-3463
-
-
Morimitsu, Y.1
Nakagawa, Y.2
Hayashi, K.3
Fujii, H.4
Kumagai, T.5
Nakamura, Y.6
Osawa, T.7
Horio, F.8
Itoh, K.9
Iida, K.10
Yamamoto, M.11
Uchida, K.12
-
116
-
-
79751529435
-
Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts
-
Ernst IM, Wagner AE, Schuemann C, Storm N, Hoppner W, Doring F, et al. Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts. Pharmacol Res. 2011;63:233-40.
-
(2011)
Pharmacol Res.
, vol.63
, pp. 233-240
-
-
Ernst, I.M.1
Wagner, A.E.2
Schuemann, C.3
Storm, N.4
Hoppner, W.5
Doring, F.6
-
117
-
-
49749133236
-
Enzymatic metabolites of lycopene induce Nrf2-mediated expression of phase II detoxifying/ antioxidant enzymes in human bronchial epithelial cells
-
Lianand F, Wang XD. Enzymatic metabolites of lycopene induce Nrf2-mediated expression of phase II detoxifying/ antioxidant enzymes in human bronchial epithelial cells. Int J Cancer. 2008;123:1262-8.
-
(2008)
Int J Cancer.
, vol.123
, pp. 1262-1268
-
-
Lianand, F.1
Wang, X.D.2
-
118
-
-
67651020758
-
Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system
-
Linnewiel K, Ernst H, Caris-Veyrat C, Ben-Dor A, Kampf A, Salman H, et al. Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system. Free Radic Biol Med. 2009;47:659-67.
-
(2009)
Free Radic Biol Med.
, vol.47
, pp. 659-667
-
-
Linnewiel, K.1
Ernst, H.2
Caris-Veyrat, C.3
Ben-Dor, A.4
Kampf, A.5
Salman, H.6
-
119
-
-
2542428247
-
Natural occurrence of cancer-preventive geranylgeranoic acid in medicinal herbs
-
DOI 10.1194/jlr.M300502-JLR200
-
Shidojiand Y, Ogawa H. Natural occurrence of cancerpreventive geranylgeranoic acid in medicinal herbs. J Lipid Res. 2004;45:1092-103. (Pubitemid 38679505)
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.6
, pp. 1092-1103
-
-
Shidoji, Y.1
Ogawa, H.2
-
120
-
-
33644508363
-
Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment
-
DOI 10.1016/j.ijdevneu.2005.11.002, PII S0736574805001462, Neural Signal Transduction in Health and Disease - Cytokinesd, Mitochondrial Dysfunction and Transport Processes
-
Reiser G, Schonfeld P, Kahlert S. Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment. Int J Dev Neurosci. 2006;24:113-22. (Pubitemid 43294617)
-
(2006)
International Journal of Developmental Neuroscience
, vol.24
, Issue.2-3
, pp. 113-122
-
-
Reiser, G.1
Schonfeld, P.2
Kahlert, S.3
-
121
-
-
33646902437
-
Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid
-
DOI 10.1016/j.febslet.2006.05.040, PII S0014579306006405
-
Bunik VI, Raddatz G, Wanders RJ, Reiser G. Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid. FEBS Lett. 2006;580:3551-7. (Pubitemid 43795920)
-
(2006)
FEBS Letters
, vol.580
, Issue.14
, pp. 3551-3557
-
-
Bunik, V.I.1
Raddatz, G.2
Wanders, R.J.A.3
Reiser, G.4
-
122
-
-
78649660058
-
Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: Role of oxidative stress
-
Yuzefovych L, Wilson G, Rachek L. Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Am J Physiol Endocrinol Metab. 2010;299:E1096-105.
-
(2010)
Am J Physiol Endocrinol Metab.
, vol.299
-
-
Yuzefovych, L.1
Wilson, G.2
Rachek, L.3
-
123
-
-
77956911862
-
Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction
-
Lu X, Yu H, Ma Q, Shen S, Das UN. Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction. Lipids Health Dis. 2010;9:106.
-
(2010)
Lipids Health Dis.
, vol.9
, pp. 106
-
-
Lu, X.1
Yu, H.2
Ma, Q.3
Shen, S.4
Das, U.N.5
-
124
-
-
70349326747
-
The polyacetylenes falcarinol and falcarindiol affect stress responses in myotube cultures in a biphasic manner
-
Young JF, Christensen LP, Theil PK, Oksbjerg N. The polyacetylenes falcarinol and falcarindiol affect stress responses in myotube cultures in a biphasic manner. Dose Response. 2008;6:239-51.
-
(2008)
Dose Response.
, vol.6
, pp. 239-251
-
-
Young, J.F.1
Christensen, L.P.2
Theil, P.K.3
Oksbjerg, N.4
-
125
-
-
84856222677
-
Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidasedependent generation of reactive oxygen species
-
in press
-
Kim JY, Yu SJ, Oh HJ, Lee JY, Kim Y, Sohn J. Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidasedependent generation of reactive oxygen species. Apoptosis. 2010; in press.
-
(2010)
Apoptosis
-
-
Kim, J.Y.1
Yu, S.J.2
Oh, H.J.3
Lee, J.Y.4
Kim, Y.5
Sohn, J.6
-
126
-
-
60849112240
-
Effect of liquiritigenin, a flavanone existed from Radix glycyrrhizae on pro-apoptotic in SMMC-7721 cells
-
Zhang SP, Zhou YJ, Liu Y, Cai YQ. Effect of liquiritigenin, a flavanone existed from Radix glycyrrhizae on pro-apoptotic in SMMC-7721 cells. Food Chem Toxicol. 2009;47:693-701.
-
(2009)
Food Chem Toxicol.
, vol.47
, pp. 693-701
-
-
Zhang, S.P.1
Zhou, Y.J.2
Liu, Y.3
Cai, Y.Q.4
-
127
-
-
50249105840
-
Naringenin-7-O-glucoside protects against doxorubicin-induced toxicity in H9c2 cardiomyocytes by induction of endogenous antioxidant enzymes
-
Han X, Pan J, Ren D, Cheng Y, Fan P, Lou H. Naringenin-7-O-glucoside protects against doxorubicin-induced toxicity in H9c2 cardiomyocytes by induction of endogenous antioxidant enzymes. Food Chem Toxicol. 2008;46:3140-6.
-
(2008)
Food Chem Toxicol.
, vol.46
, pp. 3140-3146
-
-
Han, X.1
Pan, J.2
Ren, D.3
Cheng, Y.4
Fan, P.5
Lou, H.6
-
128
-
-
34748887195
-
Kaempferol induces apoptosis in glioblastoma cells through oxidative stress
-
DOI 10.1158/1535-7163.MCT-06-0788
-
Sharma V, Joseph C, Ghosh S, Agarwal A, Mishra MK, Sen E. Kaempferol induces apoptosis in glioblastoma cells through oxidative stress. Mol Cancer Ther. 2007;6:2544-53. (Pubitemid 47480420)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.9
, pp. 2544-2553
-
-
Sharma, V.1
Joseph, C.2
Ghosh, S.3
Agarwal, A.4
Mishra, M.K.5
Sen, E.6
-
129
-
-
77949275161
-
Kaempferol suppresses cisplatin-induced apoptosis via inductions of heme oxygenase-1 and glutamate-cysteine ligase catalytic subunit in HEI-OC1 cell
-
Gao SS, Choi BM, Chen XY, Zhu RZ, Kim Y, So H, et al. Kaempferol suppresses cisplatin-induced apoptosis via inductions of heme oxygenase-1 and glutamate-cysteine ligase catalytic subunit in HEI-OC1 cell. Pharm Res. 2010;27:235-45.
-
(2010)
Pharm Res.
, vol.27
, pp. 235-245
-
-
Gao, S.S.1
Choi, B.M.2
Chen, X.Y.3
Zhu, R.Z.4
Kim, Y.5
So, H.6
-
130
-
-
67349218391
-
Regulation of heme oxygenase-1 expression and MAPK pathways in response to kaempferol and rhamnocitrin in PC12 cells
-
Hong JT, Yen JH, Wang L, Lo YH, Chen ZT, Wu MJ. Regulation of heme oxygenase-1 expression and MAPK pathways in response to kaempferol and rhamnocitrin in PC12 cells. Toxicol Appl Pharmacol. 2009;237:59-68.
-
(2009)
Toxicol Appl Pharmacol.
, vol.237
, pp. 59-68
-
-
Hong, J.T.1
Yen, J.H.2
Wang, L.3
Lo, Y.H.4
Chen, Z.T.5
Wu, M.J.6
-
131
-
-
65249157982
-
Eupatilin with heme oxygenase-1-inducing ability protects cultured feline esophageal epithelial cells from cell damage caused by indomethacin
-
Song HJ, Shin CY, Oh TY, Min YS, Park ES, Sohn UD. Eupatilin with heme oxygenase-1-inducing ability protects cultured feline esophageal epithelial cells from cell damage caused by indomethacin. Biol Pharm Bull. 2009;32:589-96.
-
(2009)
Biol Pharm Bull.
, vol.32
, pp. 589-596
-
-
Song, H.J.1
Shin, C.Y.2
Oh, T.Y.3
Min, Y.S.4
Park, E.S.5
Sohn, U.D.6
-
132
-
-
34247853280
-
Jaceosidin induces apoptosis in ras-transformed human breast epithelial cells through generation of reactive oxygen species
-
Kim MJ, Kim DH, Lee KW, Yoon DY, Surh YJ. Jaceosidin induces apoptosis in ras-transformed human breast epithelial cells through generation of reactive oxygen species. Ann N Y Acad Sci. 2007;1095:483-95.
-
(2007)
Ann N y Acad Sci.
, vol.1095
, pp. 483-495
-
-
Kim, M.J.1
Kim, D.H.2
Lee, K.W.3
Yoon, D.Y.4
Surh, Y.J.5
-
133
-
-
78650738673
-
Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - Role of the redox-regulated transcription factor Nrf2
-
Wagner AE, Boesch-Saadatmandi C, Breckwoldt D, Schrader C, Schmelzer C, Doring F, et al. Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2. BMC Complement Altern Med. 2011; 11:1.
-
(2011)
BMC Complement Altern Med.
, vol.11
, pp. 1
-
-
Wagner, A.E.1
Boesch-Saadatmandi, C.2
Breckwoldt, D.3
Schrader, C.4
Schmelzer, C.5
Doring, F.6
-
134
-
-
47349090618
-
Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells
-
DOI 10.1021/jf800175a
-
Juan ME, Wenzel U, Daniel H, Planas JM. Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells. J Agric Food Chem. 2008;56:4813-8. (Pubitemid 351999415)
-
(2008)
Journal of Agricultural and Food Chemistry
, vol.56
, Issue.12
, pp. 4813-4818
-
-
Juan, M.E.1
Wenzel, U.2
Daniel, H.3
Planas, J.M.4
-
135
-
-
34247282872
-
Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin
-
DOI 10.1016/j.freeradbiomed.2007.02.017, PII S0891584907001487
-
Tanigawa S, Fujii M, Hou DX. Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin. Free Radic Biol Med. 2007;42:1690-703. (Pubitemid 46617147)
-
(2007)
Free Radical Biology and Medicine
, vol.42
, Issue.11
, pp. 1690-1703
-
-
Tanigawa, S.1
Fujii, M.2
Hou, D.-X.3
-
136
-
-
34347392509
-
Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways
-
DOI 10.1016/j.jhep.2007.02.008, PII S0168827807001225
-
Yao P, Nussler A, Liu L, Hao L, Song F, Schirmeier A, et al. Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. J Hepatol. 2007;47:253-61. (Pubitemid 47023137)
-
(2007)
Journal of Hepatology
, vol.47
, Issue.2
, pp. 253-261
-
-
Yao, P.1
Nussler, A.2
Liu, L.3
Hao, L.4
Song, F.5
Schirmeier, A.6
Nussler, N.7
-
137
-
-
23944513613
-
Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments
-
DOI 10.1016/j.taap.2005.01.004, PII S0041008X05000128
-
Razaand H, John A. Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments. Toxicol Appl Pharmacol. 2005;207:212-20. (Pubitemid 41207914)
-
(2005)
Toxicology and Applied Pharmacology
, vol.207
, Issue.3
, pp. 212-220
-
-
Raza, H.1
John, A.2
-
138
-
-
77952023804
-
Prooxidative effects of green tea polyphenol (-)-epigallocatechin-3- gallate on the HIT-T15 pancreatic beta cell line
-
Suh KS, Chon S, Oh S, Kim SW, Kim JW, Kim YS, et al. Prooxidative effects of green tea polyphenol (-)-epigallocatechin-3-gallate on the HIT-T15 pancreatic beta cell line. Cell Biol Toxicol. 2010;26:189-99.
-
(2010)
Cell Biol Toxicol.
, vol.26
, pp. 189-199
-
-
Suh, K.S.1
Chon, S.2
Oh, S.3
Kim, S.W.4
Kim, J.W.5
Kim, Y.S.6
-
139
-
-
39249085843
-
Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG
-
Naand HK, Surh YJ. Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. Food Chem Toxicol. 2008;46:1271-8.
-
(2008)
Food Chem Toxicol.
, vol.46
, pp. 1271-1278
-
-
Naand, H.K.1
Surh, Y.J.2
-
140
-
-
77951546947
-
The major green tea polyphenol, (-)- epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress
-
Romeo L, Intrieri M, D'Agata V, Mangano NG, Oriani G, Ontario ML, et al. The major green tea polyphenol, (-)- epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress. J Am Coll Nutr. 2009;28(Suppl): 492S-9S.
-
(2009)
J Am Coll Nutr.
, vol.28
, Issue.SUPPL.
-
-
Romeo, L.1
Intrieri, M.2
D'agata, V.3
Mangano, N.G.4
Oriani, G.5
Ontario, M.L.6
-
141
-
-
77956339120
-
Protective effects of hesperidin against oxidative stress of tert-butyl hydroperoxide in human hepatocytes
-
Chen M, Gu H, Ye Y, Lin B, Sun L, Deng W, et al. Protective effects of hesperidin against oxidative stress of tert-butyl hydroperoxide in human hepatocytes. Food Chem Toxicol. 2010;48:2980-7.
-
(2010)
Food Chem Toxicol.
, vol.48
, pp. 2980-2987
-
-
Chen, M.1
Gu, H.2
Ye, Y.3
Lin, B.4
Sun, L.5
Deng, W.6
-
142
-
-
77949807509
-
Hesperidin upregulates heme oxygenase-1 to attenuate hydrogen
-
Chen MC, Ye YY, Ji G, Liu JW. Hesperidin upregulates heme oxygenase-1 to attenuate hydrogen peroxide-induced cell damage in hepatic L02 cells. J Agric Food Chem. 2010;58:3330-5.
-
(2010)
J Agric Food Chem.
, vol.58
, pp. 3330-3335
-
-
Chen, M.C.1
Ye, Y.Y.2
Ji, G.3
Liu, J.W.4
-
143
-
-
77952035101
-
Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells
-
Tamaki Y, Tabuchi T, Takahashi T, Kosaka K, Satoh T. Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells. Planta Med. 2010;76:683-8.
-
(2010)
Planta Med.
, vol.76
, pp. 683-688
-
-
Tamaki, Y.1
Tabuchi, T.2
Takahashi, T.3
Kosaka, K.4
Satoh, T.5
-
144
-
-
78650299890
-
Anthocyanins from purple sweet potato attenuate dimethylnitrosamine- induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression
-
Hwang YP, Choi JH, Yun HJ, Han EH, Kim HG, Kim JY, et al. Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression. Food Chem Toxicol. 2011;49:93-9.
-
(2011)
Food Chem Toxicol.
, vol.49
, pp. 93-99
-
-
Hwang, Y.P.1
Choi, J.H.2
Yun, H.J.3
Han, E.H.4
Kim, H.G.5
Kim, J.Y.6
-
145
-
-
34250324303
-
Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress
-
DOI 10.1074/jbc.M610616200
-
Feng R, Ni HM, Wang SY, Tourkova IL, Shurin MR, Harada H, et al. Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress. J Biol Chem. 2007;282:13468-76. (Pubitemid 47100551)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.18
, pp. 13468-13476
-
-
Feng, R.1
Ni, H.-M.2
Wang, S.Y.3
Tourkova, I.L.4
Shurin, M.R.5
Harada, H.6
Yin, X.-M.7
-
146
-
-
79954574731
-
Protocatechuic acid induces antioxidant/detoxifying enzyme expression through JNK-mediated Nrf2 activation in murine macrophages
-
in press
-
Vari R, D'Archivio M, Filesi C, Carotenuto S, Scazzocchio B, Santangelo C, et al. Protocatechuic acid induces antioxidant/detoxifying enzyme expression through JNK-mediated Nrf2 activation in murine macrophages. J Nutr Biochem. (2010); in press.
-
(2010)
J Nutr Biochem.
-
-
Vari, R.1
D'archivio, M.2
Filesi, C.3
Carotenuto, S.4
Scazzocchio, B.5
Santangelo, C.6
-
147
-
-
67650651898
-
[6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells
-
Nigam N, Bhui K, Prasad S, George J, Shukla Y. [6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells. Chem Biol Interact. 2009;181:77-84.
-
(2009)
Chem Biol Interact.
, vol.181
, pp. 77-84
-
-
Nigam, N.1
Bhui, K.2
Prasad, S.3
George, J.4
Shukla, Y.5
-
148
-
-
34047135039
-
[6]-gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo
-
DOI 10.1080/10715760701209896, PII 776348506
-
Kim JK, Kim Y, Na KM, Surh YJ, Kim TY. [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. Free Radic Res. 2007;41:603-14. (Pubitemid 46511125)
-
(2007)
Free Radical Research
, vol.41
, Issue.5
, pp. 603-614
-
-
Kim, J.-K.1
Kim, Y.2
Na, K.-M.3
Surh, Y.-J.4
Kim, T.-Y.5
-
149
-
-
77950920856
-
Genotoxic effect of 6-gingerol on human hepatoma G2 cells
-
Yang G, Zhong L, Jiang L, Geng C, Cao J, Sun X, et al. Genotoxic effect of 6-gingerol on human hepatoma G2 cells. Chem Biol Interact. 2010;185:12-7.
-
(2010)
Chem Biol Interact.
, vol.185
, pp. 12-17
-
-
Yang, G.1
Zhong, L.2
Jiang, L.3
Geng, C.4
Cao, J.5
Sun, X.6
-
150
-
-
77649187285
-
Capsaicin mediates cell death in bladder cancer T24 cells through reactive oxygen species production and mitochondrial depolarization
-
Yang ZH, Wang XH, Wang HP, Hu LQ, Zheng XM, Li SW. Capsaicin mediates cell death in bladder cancer T24 cells through reactive oxygen species production and mitochondrial depolarization. Urology. 2010;75:735-41.
-
(2010)
Urology
, vol.75
, pp. 735-741
-
-
Yang, Z.H.1
Wang, X.H.2
Wang, H.P.3
Hu, L.Q.4
Zheng, X.M.5
Li, S.W.6
-
151
-
-
70349570949
-
Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines
-
YangKM, Pyo JO, Kim GY, Yu R, Han IS, Ju SA, et al. Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines. Cell Mol Biol Lett. 2009;14:497-510.
-
(2009)
Cell Mol Biol Lett.
, vol.14
, pp. 497-510
-
-
Yang, K.M.1
Pyo, J.O.2
Kim, G.Y.3
Yu, R.4
Han, I.S.5
Ju, S.A.6
-
152
-
-
61449229473
-
Capsaicin-induced apoptosis in human hepatoma HepG2 cells
-
Huang SP, Chen JC, Wu CC, Chen CT, Tang NY, Ho YT, et al. Capsaicin-induced apoptosis in human hepatoma HepG2 cells. Anticancer Res. 2009;29:165-74.
-
(2009)
Anticancer Res.
, vol.29
, pp. 165-174
-
-
Huang, S.P.1
Chen, J.C.2
Wu, C.C.3
Chen, C.T.4
Tang, N.Y.5
Ho, Y.T.6
-
153
-
-
35848954977
-
Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target
-
DOI 10.1089/ars.2007.1827
-
Joung EJ, Li MH, Lee HG, Somparn N, Jung YS, Na HK, et al. Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target. Antioxid Redox Signal. 2007;9:2087-98. (Pubitemid 350059030)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.12
, pp. 2087-2098
-
-
Joung, E.-J.1
Li, M.-H.2
Lee, H.G.3
Somparn, N.4
Jung, Y.S.5
Na, H.-K.6
Kim, S.-H.7
Cha, Y.-N.8
Surh, Y.-J.9
-
154
-
-
67349093523
-
Linalool decreases HepG2 viability by inhibiting mitochondrial complexes i and II, increasing reactive oxygen species and decreasing ATP and GSH levels
-
Usta J, Kreydiyyeh S, Knio K, Barnabe P, Bou-Moughlabay Y, Dagher S. Linalool decreases HepG2 viability by inhibiting mitochondrial complexes I and II, increasing reactive oxygen species and decreasing ATP and GSH levels. Chem Biol Interact. 2009;180:39-46.
-
(2009)
Chem Biol Interact.
, vol.180
, pp. 39-46
-
-
Usta, J.1
Kreydiyyeh, S.2
Knio, K.3
Barnabe, P.4
Bou-Moughlabay, Y.5
Dagher, S.6
-
155
-
-
46749135955
-
The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine- derived oxidative stress
-
Hwangand YP, Jeong HG. The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress. FEBS Lett. 2008;582:2655-62.
-
(2008)
FEBS Lett.
, vol.582
, pp. 2655-2662
-
-
Hwangand, Y.P.1
Jeong, H.G.2
|