Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines

Cellular and Molecular Biology Letters

Volumn 14, Issue 3, 2009, Pages 497-510

  Kyung, Min Yang ^a   Jong, Ok Pyo ^b   Kim, Gyu Yeol ^c   Yu, Rina ^d   In, Seob Han ^d   Ju, Seong A ^c   Won, Ho Kim ^a   Kim, Byung Sam ^d  

^a Yonsei University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Ulsan University College of Medicine   (South Korea)

^d University of Ulsan   (South Korea)

Author keywords

Apoptosis; Capsaicin; Caspase 3; Colon cancer cell line; Mitochondrial transmembrane potential; Reactive oxygen species

Indexed keywords

CAPSAICIN; CASPASE 3; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CELL DEATH; CELL STRUCTURE; CELL TYPE; CELL VIABILITY; CHEMOPROPHYLAXIS; COLON CANCER; CONTROLLED STUDY; DNA CONTENT; DNA FRAGMENTATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIPID TRANSPORT; MITOCHONDRIAL MEMBRANE POTENTIAL; COLON TUMOR; DRUG EFFECT; METABOLISM; MITOCHONDRION; PATHOLOGY; TUMOR CELL LINE;

CAPSICUM FRUTESCENS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CAPSAICIN; CASPASE 3; CELL LINE, TUMOR; COLONIC NEOPLASMS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 70349570949     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-009-0016-2     Document Type: Article

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