Juglone-induced apoptosis in human gastric cancer SGC-7901 cells via the mitochondrial pathway

Experimental and Toxicologic Pathology

Volumn 63, Issue 1-2, 2011, Pages 69-78

  Ji Yu Bin, Y B ^a,b   Qu, Zhong Yuan ^a,b   Zou, Xiang ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b HARBIN UNIVERSITY OF COMMERCE   (China)

Author keywords

Apoptosis; Juglone; Mitochondrial pathway; ROS; SGC 7901 cells

Indexed keywords

10 HYDROXYCAMPTOTHECIN; CASPASE 3; CYTOCHROME C; JUGLONE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SULFORHODAMINE B;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN EXPRESSION; STOMACH CANCER; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CELL LINE, TUMOR; CYTOCHROMES C; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; NAPHTHOQUINONES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; STOMACH NEOPLASMS;

EID: 78650171632     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2009.09.010     Document Type: Article

References (36)

1. Antonsson B., Montessuit S., Sanchez B., Martinou J.C. Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J Biol Chem 2001, 276:11615-11623.
2. Babich H., Stern A. In vitro cytotoxicities of 1,4-naphthoquinone and hydroxylated 1,4-naphthoquinones to replicating cells. J Appl Toxicol 1993, 13:353-358.
3. Belmokhtar C.A., Hillion J., Segal-Bendirdjian E. Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. Oncogene 2001, 20:3354-3362.
4. Bhuyan K.C., Bhuyan D.K., Podos S.M. Free radical enhancer xenobiotic is an inducer of cataract in rabbit. Free Radical Res Commun 1991, 12-13(Pt 2):609-620.
5. Bolton J.L., Trush M.A., Penning T.M., Dryhurst G., Monks T.J. Role of quinones in toxicology. Chem Res Toxicol 2000, 13:135-160.
6. Bouchier-Hayes L., Munoz-Pinedo C., Connell S., Green D.R. Measuring apoptosis at the single cell level. Methods 2008, 44:222-228.
7. Brumatti G., Sheridan C., Martin S.J. Expression and purification of recombinant annexin V for the detection of membrane alterations on apoptotic cells. Methods 2008, 44:235-240.
8. Das R., Roy A., Dutta N., Majumder H.K. Reactive oxygen species and imbalance of calcium homeostasis contributes to curcumin induced programmed cell death in Leishmania donovani. Apoptosis 2008, 13:867-882.
9. Dias N., Bailly C. Drugs targeting mitochondrial functions to control tumor cell growth. Biochem Pharmacol 2005, 70:1-12.
10. Ferlay J., Bray F., Pisani P., Parkin D.M. Globocan 2000 Cancer Incidence, Mortality and Prevalence Worldwide 2004, IARC Press, Lyon.
11. Funt RC, Martin J. Black walnut toxicity to plants, humans and horses. Ohio State University Extension Fact sheet, HYG-1148-93, 1993.
12. Gatti L., Perego P. Cellular resistance to oxaliplatin and drug accumulation defects. Cellular resistance to oxaliplatin and drug accumulation defects platinum and other heavy metal compounds in cancer chemotherapy 2009, Humana Press. A. Bonetti, R. Leone, F.M. Muggia, S.B. Howell (Eds.).
13. Harris M.H., Thompson C.B. The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability. Cell Death Differ 2000, 7:1182-1191.
14. Heimlich G., McKinnon A.D., Bernardo K., Brdiczka D., Reed J.C., Kain R., et al. Bax-induced cytochrome c release from mitochondria depends on alpha-helices-5 and -6. Biochem J 2004, 378:247-255.
15. Hochman A., Sternin H., Gorodin S., Korsmeyer S., Ziv I., Melamed E., et al. Enhanced oxidative stress and altered antioxidants in brains of Bcl-2-deficient mice. J Neurochem 1998, 71:741-748.
16. Ito K., Nakazato T., Yamato K., Miyakawa Y., Yamada T., Hozumi N., et al. Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species. Cancer Res 2004, 64:1071-1078.
17. Ji Y.B., Gao S.Y., Ji C.F., Zou X. Induction of apoptosis in HepG2 cells by solanine and Bcl-2 protein. J Ethnopharmacol 2008, 115:194-202.
18. Ji Y.B., Qu Z.Y., Zou X., Cui L., Hu G.J. Growth inhibition and induction of apoptosis in sarcoma 180 cells by juglone in vivo (session 5). International seminar on future biomedical information engineering 2008, 325-328. Engineering Technology Press. L. Qi (Ed.).
19. Johnson J.J., Syed D.N., Heren C.R., Suh Y., Adhami V.M., Mukhtar H. Carnosol, a dietary diterpene, displays growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5'-AMP-activated protein kinase (AMPK) pathway. Pharm Res 2008, 25:2125-2134.
20. Kamei H., Koide T., Kojima T., Hashimoto Y., Hasegawa M. Inhibition of cell growth in culture by quinones. Cancer Biother Radiopharm 1998, 13:185-188.
21. Kothakota S., Azuma T., Reinhard C., Klippel A., Tang J., Chu K., et al. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 1997, 278:294-298.
22. Kroemer G., Dallaporta B., Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998, 60:619-642.
23. Krysko D.V., Vanden Berghe T., D'Herde K., Vandenabeele P. Apoptosis and necrosis: detection, discrimination and phagocytosis. Methods 2008, 44:205-221.
24. Launay S., Hermine O., Fontenay M., Kroemer G., Solary E., Garrido C. Vital functions for lethal caspases. Oncogene 2005, 24:5137-5148.
25. Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997, 91:479-489.
26. Liu L., Li W., Koike K., Zhang S., Nikaido T. New alpha-tetralonyl glucosides from the fruit of Juglans mandshurica. Chem Pharm Bull (Tokyo) 2004, 52:566-569.
27. Monks T.J., Hanzlik R.P., Cohen G.M., Ross D., Graham D.G. Quinone chemistry and toxicity. Toxicol Appl Pharmacol 1992, 112:2-16.
28. O'Neill J.W., Hockenbery D.M. Bcl-2-related proteins as drug targets. Curr Med Chem 2003, 10:1553-1562.
29. Sambaziotis D., Kapranos N., Kontogeorgos G. Correlation of bcl-2 and bax with apoptosis in human pituitary adenomas. Pituitary 2003, 6:127-133.
30. Segura-Aguilar J., Jonsson K., Tidefelt U., Paul C. The cytotoxic effects of 5-OH-1,4-naphthoquinone and 5,8-diOH-1,4-naphthoquinone on doxorubicin-resistant human leukemia cells (HL-60). Leuk Res 1992, 16:631-637.
31. Sonnemann J., Gange J., Pilz S., Stotzer C., Ohlinger R., Belau A., et al. Comparative evaluation of the treatment efficacy of suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lines and primary ovarian cancer cells from patients. BMC Cancer 2006, 6:183.
32. Sugie S., Okamoto K., Rahman K.M., Tanaka T., Kawai K., Yamahara J., et al. Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats. Cancer Lett 1998, 127:177-183.
33. Suzuki N., Urano J., Tamanoi F. Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells. Proc Natl Acad Sci USA 1998, 95:15356-15361.
34. Yethon J.A., Epand R.F., Leber B., Epand R.M., Andrews D.W. Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis. J Biol Chem 2003, 278:48935-48941.
35. Zhang R., Humphreys I., Sahu R.P., Shi Y., Srivastava S.K. In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway. Apoptosis 2008, 13:1465-1478.
36. Zimmermann A.K., Loucks F.A., Schroeder E.K., Bouchard R.J., Tyler K.L., Linseman D.A. Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria. J Biol Chem 2007, 282:29296-29304.