-
1
-
-
26944464241
-
Cytotoxic and apoptotic activities of diarylheptanoids and gingerol-related compounds from the rhizome of Chinese ginger
-
Wei Q.Y., Ma J.P., Cai Y.J., Yang L., Liu Z.L. Cytotoxic and apoptotic activities of diarylheptanoids and gingerol-related compounds from the rhizome of Chinese ginger. J. Ethnopharmacol. 2005, 102:177-184.
-
(2005)
J. Ethnopharmacol.
, vol.102
, pp. 177-184
-
-
Wei, Q.Y.1
Ma, J.P.2
Cai, Y.J.3
Yang, L.4
Liu, Z.L.5
-
2
-
-
34248562439
-
Possible controversy over dietary polyphenols: benefits vs. risks
-
Lambert J.D., Sang S., Yang C.S. Possible controversy over dietary polyphenols: benefits vs. risks. Chem. Res. Toxicol. 2007, 20:583-585.
-
(2007)
Chem. Res. Toxicol.
, vol.20
, pp. 583-585
-
-
Lambert, J.D.1
Sang, S.2
Yang, C.S.3
-
3
-
-
0028775357
-
Infant leukemia, topoisomerase II inhibitors, and the MLL gene
-
Ross J.A., Potter J.D., Robison L.L. Infant leukemia, topoisomerase II inhibitors, and the MLL gene. J. Natl. Cancer Inst. 1994, 86:1678-1680.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1678-1680
-
-
Ross, J.A.1
Potter, J.D.2
Robison, L.L.3
-
4
-
-
31644435641
-
Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins
-
Galati G., Lin A., Sultan A.M., O'Brien P.J. Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radic. Biol. Med. 2006, 40:570-580.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 570-580
-
-
Galati, G.1
Lin, A.2
Sultan, A.M.3
O'Brien, P.J.4
-
5
-
-
41849124923
-
[6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells
-
Lee H.S., Seo E.Y., Kang N.E., Kim W.K. [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells. J. Nutr. Biochem. 2008, 19:313-319.
-
(2008)
J. Nutr. Biochem.
, vol.19
, pp. 313-319
-
-
Lee, H.S.1
Seo, E.Y.2
Kang, N.E.3
Kim, W.K.4
-
6
-
-
0035110888
-
Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol
-
Bode A.M., Ma W.Y., Surh Y.J., Dong Z. Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol. Cancer Res. 2001, 61:850-853.
-
(2001)
Cancer Res.
, vol.61
, pp. 850-853
-
-
Bode, A.M.1
Ma, W.Y.2
Surh, Y.J.3
Dong, Z.4
-
7
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh Y.J. Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 2003, 3:768-780.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
8
-
-
23744431584
-
[6]-Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo
-
Kim E.C., Min J.K., Kim T.Y., Lee S.J., Yang H.O., Han S., Kim Y.M., Kwon Y.G. [6]-Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo. Biochem. Biophys. Res. Commun. 2005, 335:300-308.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.335
, pp. 300-308
-
-
Kim, E.C.1
Min, J.K.2
Kim, T.Y.3
Lee, S.J.4
Yang, H.O.5
Han, S.6
Kim, Y.M.7
Kwon, Y.G.8
-
9
-
-
34249080113
-
Curcumin-induced genotoxicity and antigenotoxicity in HepG2 cells
-
Cao J., Jiang L.P., Liu Y., Yang G., Yao X.F., Zhong L.F. Curcumin-induced genotoxicity and antigenotoxicity in HepG2 cells. Toxicon 2007, 49:1219-1222.
-
(2007)
Toxicon
, vol.49
, pp. 1219-1222
-
-
Cao, J.1
Jiang, L.P.2
Liu, Y.3
Yang, G.4
Yao, X.F.5
Zhong, L.F.6
-
10
-
-
0021029044
-
The active part of the [6]-gingerol molecule in mutagenesis
-
Nakamura H., Yamamoto T. The active part of the [6]-gingerol molecule in mutagenesis. Mutat. Res. 1983, 122:87-94.
-
(1983)
Mutat. Res.
, vol.122
, pp. 87-94
-
-
Nakamura, H.1
Yamamoto, T.2
-
12
-
-
0033756474
-
Cathepsin B contributes to TNFalpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
Guicciardi M.E., Deussing J., Miyoshi H., Bronk S.F., Svingen P.A., Peters C., Kaufmann S.H., Gores G.J. Cathepsin B contributes to TNFalpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J. Clin. Invest. 2000, 106:1127-1137.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
Deussing, J.2
Miyoshi, H.3
Bronk, S.F.4
Svingen, P.A.5
Peters, C.6
Kaufmann, S.H.7
Gores, G.J.8
-
13
-
-
64849090408
-
Microglia-aging: roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging
-
Nakanishi H., Wu Z. Microglia-aging: roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging. Behav. Brain Res. 2009, 201:1-7.
-
(2009)
Behav. Brain Res.
, vol.201
, pp. 1-7
-
-
Nakanishi, H.1
Wu, Z.2
-
14
-
-
0031897739
-
Oxidative stress causes relocation of the lysosomal enzyme cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes
-
Roberg K., Ollinger K. Oxidative stress causes relocation of the lysosomal enzyme cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes. Am. J. Pathol. 1998, 152:1151-1156.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 1151-1156
-
-
Roberg, K.1
Ollinger, K.2
-
16
-
-
34247567046
-
Benzo[a]pyrene-induced elevation of GSH level protects against oxidative stress and enhances xenobiotic detoxification in human HepG2 cells
-
Lin T., Yang M.S. Benzo[a]pyrene-induced elevation of GSH level protects against oxidative stress and enhances xenobiotic detoxification in human HepG2 cells. Toxicology 2007, 235:1-10.
-
(2007)
Toxicology
, vol.235
, pp. 1-10
-
-
Lin, T.1
Yang, M.S.2
-
17
-
-
0021193203
-
Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
-
Ostling O., Johanson K.J. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 1984, 123:291-298.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.123
, pp. 291-298
-
-
Ostling, O.1
Johanson, K.J.2
-
18
-
-
0030805031
-
The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction
-
Kirsch-Volders M., Elhajouji A., Cundari E., Van Hummelen P. The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. Mutat. Res. 1997, 392:19-30.
-
(1997)
Mutat. Res.
, vol.392
, pp. 19-30
-
-
Kirsch-Volders, M.1
Elhajouji, A.2
Cundari, E.3
Van Hummelen, P.4
-
19
-
-
0030797051
-
Formation, prevention and repair of DNA damage by iron/hydrogen peroxide
-
Henle E.S., Linn S. Formation, prevention and repair of DNA damage by iron/hydrogen peroxide. J. Biol. Chem. 1997, 272:19095-19098.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19095-19098
-
-
Henle, E.S.1
Linn, S.2
-
20
-
-
0030968310
-
Microgel electrophoresis: sensitivity, mechanisms, and DNA electrostretching
-
Singh N.P., Stephens R.E. Microgel electrophoresis: sensitivity, mechanisms, and DNA electrostretching. Mutat. Res. 1997, 383:167-175.
-
(1997)
Mutat. Res.
, vol.383
, pp. 167-175
-
-
Singh, N.P.1
Stephens, R.E.2
-
21
-
-
0025832194
-
Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens
-
Natarajan A.T., Darroudi F. Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens. Mutagenesis 1991, 6:399-403.
-
(1991)
Mutagenesis
, vol.6
, pp. 399-403
-
-
Natarajan, A.T.1
Darroudi, F.2
-
22
-
-
0014328582
-
Chromosomal aberrations and cloning efficiency in adenovirus type 12-infected hamster cells
-
Zur Hausen H. Chromosomal aberrations and cloning efficiency in adenovirus type 12-infected hamster cells. J. Virol. 1968, 2:915-917.
-
(1968)
J. Virol.
, vol.2
, pp. 915-917
-
-
Zur Hausen, H.1
-
23
-
-
0242266944
-
Carcinogenic metal induced sites of reactive oxygen species formation in hepatocytes
-
Pourahmad J., O'Brien P.J., Jokar F., Daraei B. Carcinogenic metal induced sites of reactive oxygen species formation in hepatocytes. Toxicol. In Vitro 2003, 17:803-810.
-
(2003)
Toxicol. In Vitro
, vol.17
, pp. 803-810
-
-
Pourahmad, J.1
O'Brien, P.J.2
Jokar, F.3
Daraei, B.4
-
24
-
-
0023240626
-
Mitochondrial transmembrane potential and pH gradient during anoxia
-
Andersson B.S., Aw T.Y., Jones D.P. Mitochondrial transmembrane potential and pH gradient during anoxia. Am. J. Physiol. 1987, 252:349-355.
-
(1987)
Am. J. Physiol.
, vol.252
, pp. 349-355
-
-
Andersson, B.S.1
Aw, T.Y.2
Jones, D.P.3
-
25
-
-
21144458092
-
Protective effects of panduratin A against oxidative damage of tertbutylhydroperoxide in human HepG2 cells
-
Sohn J.H., Han K.L., Lee S.H., Hwang J.K. Protective effects of panduratin A against oxidative damage of tertbutylhydroperoxide in human HepG2 cells. Biol. Pharm. Bull. 2005, 28:1083-1086.
-
(2005)
Biol. Pharm. Bull.
, vol.28
, pp. 1083-1086
-
-
Sohn, J.H.1
Han, K.L.2
Lee, S.H.3
Hwang, J.K.4
-
26
-
-
2142824138
-
Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells
-
Kinjo J., Hirakawa T., Tsuchihashi R., Nagao T., Okawa M., Nohara T., Okabe H. Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells. Biol. Pharm. Bull. 2003, 26:1357-1360.
-
(2003)
Biol. Pharm. Bull.
, vol.26
, pp. 1357-1360
-
-
Kinjo, J.1
Hirakawa, T.2
Tsuchihashi, R.3
Nagao, T.4
Okawa, M.5
Nohara, T.6
Okabe, H.7
-
27
-
-
0030020154
-
Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1-treated rat liver and human oral mucosal cells
-
Yarborough A., Zhang Y.J., Hsu T.M., Santella R.M. Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1-treated rat liver and human oral mucosal cells. Cancer Res. 1996, 56:683-688.
-
(1996)
Cancer Res.
, vol.56
, pp. 683-688
-
-
Yarborough, A.1
Zhang, Y.J.2
Hsu, T.M.3
Santella, R.M.4
-
28
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
30
-
-
43949108922
-
The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity
-
Li Z., Berk M., McIntyre T.M., Gores G.J., Feldstein A.E. The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity. Hepatology 2008, 47:1495-1503.
-
(2008)
Hepatology
, vol.47
, pp. 1495-1503
-
-
Li, Z.1
Berk, M.2
McIntyre, T.M.3
Gores, G.J.4
Feldstein, A.E.5
-
31
-
-
0141447370
-
Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis
-
Zhao M., Antunes F., Eaton J.W., Brunk U.T. Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. Eur. J. Biochem. 2003, 270:3778-3786.
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 3778-3786
-
-
Zhao, M.1
Antunes, F.2
Eaton, J.W.3
Brunk, U.T.4
-
32
-
-
17044395830
-
Cadmium chloride-induced DNA and lysosomal damage in a hepatoma cell line
-
Fotakis G., Cemeli E., Anderson D., Timbrell J.A. Cadmium chloride-induced DNA and lysosomal damage in a hepatoma cell line. Toxicol. In Vitro 2005, 19:481-489.
-
(2005)
Toxicol. In Vitro
, vol.19
, pp. 481-489
-
-
Fotakis, G.1
Cemeli, E.2
Anderson, D.3
Timbrell, J.A.4
-
33
-
-
17144404222
-
Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells
-
Liu S.X., Davidson M.M., Tang X., Walker W.F., Athar M., Ivanov V., Hei T.K. Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells. Cancer Res. 2005, 65:3236-3242.
-
(2005)
Cancer Res.
, vol.65
, pp. 3236-3242
-
-
Liu, S.X.1
Davidson, M.M.2
Tang, X.3
Walker, W.F.4
Athar, M.5
Ivanov, V.6
Hei, T.K.7
-
34
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 1979, 59:527-605.
-
(1979)
Physiol. Rev.
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
35
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri K.F., Kroemer G. Organelle-specific initiation of cell death pathways. Nat. Cell Biol. 2001, 3:E255-E263.
-
(2001)
Nat. Cell Biol.
, vol.3
-
-
Ferri, K.F.1
Kroemer, G.2
-
36
-
-
0035887215
-
Sphingosine induced apoptosis is dependent on lysosomal proteases
-
Kågedal K., Zhao M., Svensson I., Brunk U.T. Sphingosine induced apoptosis is dependent on lysosomal proteases. Biochem. J. 2001, 359:335-343.
-
(2001)
Biochem. J.
, vol.359
, pp. 335-343
-
-
Kågedal, K.1
Zhao, M.2
Svensson, I.3
Brunk, U.T.4
-
37
-
-
0038529617
-
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
-
Boya P., Andreau K., Poncet D., Zamzami N., Perfettini J.L., Metivier D., Ojcius D.M., Jäättelä M., Kroemer G. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J. Exp. Med. 2003, 197:1323-1334.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1323-1334
-
-
Boya, P.1
Andreau, K.2
Poncet, D.3
Zamzami, N.4
Perfettini, J.L.5
Metivier, D.6
Ojcius, D.M.7
Jäättelä, M.8
Kroemer, G.9
-
38
-
-
33751251999
-
Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes
-
Van Nierop K., Muller F.J., Stap J., Van Noorden C.J., Van Eijk M., de Groot C. Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes. J. Histochem. Cytochem. 2006, 54:1425-1435.
-
(2006)
J. Histochem. Cytochem.
, vol.54
, pp. 1425-1435
-
-
Van Nierop, K.1
Muller, F.J.2
Stap, J.3
Van Noorden, C.J.4
Van Eijk, M.5
de Groot, C.6
-
39
-
-
0036293208
-
Mitochondrial DNA alterations in cancer
-
Copeland W.C., Wachsman J.T., Johnson F.M., Penta J.S. Mitochondrial DNA alterations in cancer. Cancer Invest. 2002, 20:557-569.
-
(2002)
Cancer Invest.
, vol.20
, pp. 557-569
-
-
Copeland, W.C.1
Wachsman, J.T.2
Johnson, F.M.3
Penta, J.S.4
-
40
-
-
65649145090
-
Upstream reactive oxidative species (ROS) signals in exogenous oxidative stress-induced mitochondrial dysfunction
-
Lu M., Gong X. Upstream reactive oxidative species (ROS) signals in exogenous oxidative stress-induced mitochondrial dysfunction. Cell Biol. Int. 2009, 33:658-664.
-
(2009)
Cell Biol. Int.
, vol.33
, pp. 658-664
-
-
Lu, M.1
Gong, X.2
-
41
-
-
2642573655
-
Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis
-
Sander C.S., Chang H., Hamm F., Elsner P., Thiele J.J., Thiele Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis. Int. J. Dermatol. 2004, 43:326-335.
-
(2004)
Int. J. Dermatol.
, vol.43
, pp. 326-335
-
-
Sander, C.S.1
Chang, H.2
Hamm, F.3
Elsner, P.4
Thiele, J.J.5
Thiele6
-
42
-
-
67649779548
-
Bilberry extract reduces UVA-induced oxidative stress in HaCaT keratinocytes: a pilot study
-
Svobodová A., Rambousková J., Walterová D., Vostalová J. Bilberry extract reduces UVA-induced oxidative stress in HaCaT keratinocytes: a pilot study. Biofactors 2008, 33:249-266.
-
(2008)
Biofactors
, vol.33
, pp. 249-266
-
-
Svobodová, A.1
Rambousková, J.2
Walterová, D.3
Vostalová, J.4
-
43
-
-
9444258632
-
Role of oxygen radicals in DNA damage and cancer incidence
-
Valko M., Izakovic M., Mazur M., Rhodes C.J., Telser J. Role of oxygen radicals in DNA damage and cancer incidence. Mol. Cell. Biochem. 2004, 266:37-56.
-
(2004)
Mol. Cell. Biochem.
, vol.266
, pp. 37-56
-
-
Valko, M.1
Izakovic, M.2
Mazur, M.3
Rhodes, C.J.4
Telser, J.5
-
45
-
-
0026592966
-
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions
-
Cheng K.C., Cahill D.S., Kasai H., Nishimura S., Loeb L.A. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions. J. Biol. Chem. 1992, 267:166-172.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 166-172
-
-
Cheng, K.C.1
Cahill, D.S.2
Kasai, H.3
Nishimura, S.4
Loeb, L.A.5
-
46
-
-
0027399969
-
Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G·C→T·A transversions in simian kidney cells
-
Moriya M. Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G·C→T·A transversions in simian kidney cells. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:1122-1126.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 1122-1126
-
-
Moriya, M.1
-
47
-
-
0025298097
-
Glutathione-dependent protection against oxidative injury
-
Shan X.Q., Aw T.Y., Jones D.P. Glutathione-dependent protection against oxidative injury. Pharmacol. Ther. 1990, 47:61-71.
-
(1990)
Pharmacol. Ther.
, vol.47
, pp. 61-71
-
-
Shan, X.Q.1
Aw, T.Y.2
Jones, D.P.3
-
49
-
-
0037674662
-
Illusions of safety: antimutagens can be mutagens, and anticarcinogens can be carcinogens
-
Zeiger E. Illusions of safety: antimutagens can be mutagens, and anticarcinogens can be carcinogens. Mutat. Res. 2003, 543:191-194.
-
(2003)
Mutat. Res.
, vol.543
, pp. 191-194
-
-
Zeiger, E.1
-
50
-
-
33846651857
-
Antimutagenicity of cinnamaldehyde and vanillin in human cells: global gene expression and possible role of DNA damage and repair
-
King A.A, Shaughnessy D.T., Mure K., Leszczynska J., Ward W.O., Umbach D.M., Xu Z., Ducharme D., Taylor J.A., Demarini D.M., Klein C.B. Antimutagenicity of cinnamaldehyde and vanillin in human cells: global gene expression and possible role of DNA damage and repair. Mutat. Res. 2007, 616:60-69.
-
(2007)
Mutat. Res.
, vol.616
, pp. 60-69
-
-
King, A.A.1
Shaughnessy, D.T.2
Mure, K.3
Leszczynska, J.4
Ward, W.O.5
Umbach, D.M.6
Xu, Z.7
Ducharme, D.8
Taylor, J.A.9
Demarini, D.M.10
Klein, C.B.11
|