메뉴 건너뛰기




Volumn 140, Issue 5, 2010, Pages 885-892

Sulforaphane and α-lipoic acid upregulate the expression of the π class of glutathione S-transferase through c-jun and Nrf2 activation

Author keywords

[No Author keywords available]

Indexed keywords

DIALLYL TRISULFIDE; DIHYDROLIPOATE; DNA; GLUTATHIONE TRANSFERASE; MESSENGER RNA; NUCLEAR PROTEIN; ORGANOSULFUR DERIVATIVE; PROTEIN C JUN; SULFORAPHANE; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF2;

EID: 77951480791     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.110.121418     Document Type: Article
Times cited : (63)

References (52)
  • 1
  • 2
    • 34047136753 scopus 로고    scopus 로고
    • Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis
    • DOI 10.1016/j.phrs.2007.01.009, PII S1043661807000321, Nutritional Pharmacology
    • Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol Res. 2007;55:224-236 (Pubitemid 46518152)
    • (2007) Pharmacological Research , vol.55 , Issue.3 , pp. 224-236
    • Higdon, J.V.1    Delage, B.2    Williams, D.E.3    Dashwood, R.H.4
  • 3
    • 34250191113 scopus 로고    scopus 로고
    • Garlic-derived S-allylmercaptocysteine is a novel in vivo antimetastatic agent for androgen-independent prostate cancer
    • DOI 10.1158/1078-0432.CCR-06-2074
    • Howard EW, Ling MT, Chua CW, Cheung HW, Wang X, Wong YC. Garlic-derived S-allylmercaptocysteine is a novel in vivo antimetastatic agent for androgen-independent prostate cancer. Clin Cancer Res. 2007;13:1847-1856 (Pubitemid 46952955)
    • (2007) Clinical Cancer Research , vol.13 , Issue.6 , pp. 1847-1856
    • Howard, E.W.1    Ling, M.-T.2    Chee, W.C.3    Hiu, W.C.4    Wang, X.5    Yong, C.W.6
  • 4
    • 51749083278 scopus 로고    scopus 로고
    • Associations of plasma carotenoids with risk factors and biomarkers related to cardiovascular disease in middle-aged and older women
    • Wang L, Gaziano JM, Norkus EP, Buring JE, Sesso HD. Associations of plasma carotenoids with risk factors and biomarkers related to cardiovascular disease in middle-aged and older women. Am J Clin Nutr. 2008;88:747-754
    • (2008) Am J Clin Nutr , vol.88 , pp. 747-754
    • Wang, L.1    Gaziano, J.M.2    Norkus, E.P.3    Buring, J.E.4    Sesso, H.D.5
  • 5
    • 74849114005 scopus 로고    scopus 로고
    • Green tea consumption and breast cancer risk or recurrence: A meta-analysis
    • Ogunleye AA, Xue F, Michels KB. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat. 2010;119:477-484
    • (2010) Breast Cancer Res Treat , vol.119 , pp. 477-484
    • Ogunleye, A.A.1    Xue, F.2    Michels, K.B.3
  • 6
    • 33645468736 scopus 로고    scopus 로고
    • Modest induction of phase 2 enzyme activity in the F-344 rat prostate
    • Jones SB, Brooks JD. Modest induction of phase 2 enzyme activity in the F-344 rat prostate. BMC Cancer. 2006;6:62.
    • (2006) BMC Cancer , vol.6 , pp. 62
    • Jones, S.B.1    Brooks, J.D.2
  • 7
    • 52649162392 scopus 로고    scopus 로고
    • Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an isothiocyanate structurally related to sulforaphane
    • Hanlon N, Okpara A, Coldham N, Sauer MJ, Ioannides C. Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an isothiocyanate structurally related to sulforaphane. J Agric Food Chem. 2008;56:7866-7871
    • (2008) J Agric Food Chem , vol.56 , pp. 7866-7871
    • Hanlon, N.1    Okpara, A.2    Coldham, N.3    Sauer, M.J.4    Ioannides, C.5
  • 8
    • 45849137870 scopus 로고    scopus 로고
    • Phase II enzyme induction by alpha-lipoic acid through phosphatidylinositol 3-kinase-dependent C/EBPs activation
    • Ki SH, Kim SG. Phase II enzyme induction by alpha-lipoic acid through phosphatidylinositol 3-kinase-dependent C/EBPs activation. Xenobiotica. 2008;38:587-604.
    • (2008) Xenobiotica , vol.38 , pp. 587-604
    • Ki, S.H.1    Kim, S.G.2
  • 9
    • 61549133223 scopus 로고    scopus 로고
    • Effect of broccoli (Brassica oleracea) and its phytochemical sulforaphane in balanced diets on the detoxification enzymes levels of tilapia (Oreochromis niloticus) exposed to a carcinogenic and mutagenic pollutant
    • Villa-Cruz V, Davila J, Viana MT, Vazquez-Duhalt R. Effect of broccoli (Brassica oleracea) and its phytochemical sulforaphane in balanced diets on the detoxification enzymes levels of tilapia (Oreochromis niloticus) exposed to a carcinogenic and mutagenic pollutant. Chemosphere. 2009;74:1145-1151
    • (2009) Chemosphere , vol.74 , pp. 1145-1151
    • Villa-Cruz, V.1    Davila, J.2    Viana, M.T.3    Vazquez-Duhalt, R.4
  • 11
    • 0021797851 scopus 로고
    • Purification, induction, and distribution of placental glutathione transferase: A new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis
    • DOI 10.1073/pnas.82.12.3964
    • Satoh K, Kitahara A, Soma Y, Inaba Y, Hatayama I, Sato K. Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis. Proc Natl Acad Sci USA. 1985;82:3964-3968 (Pubitemid 15052809)
    • (1985) Proceedings of the National Academy of Sciences of the United States of America , vol.82 , Issue.12 , pp. 3964-3968
    • Satoh, K.1    Kitahara, A.2    Soma, Y.3
  • 15
    • 0000877358 scopus 로고
    • Multiple regulatory elements and phorbol 12-O-tetradecanoate 13-acetate responsiveness of the rat placental glutathione transferase gene
    • DOI 10.1073/pnas.85.24.9456
    • Sakai M, Okuda A, Muramatsu M. Multiple regulatory elements and phorbol 12-O-tetradecanoate 13-acetate responsiveness of the rat placental glutathione transferase gene. Proc Natl Acad Sci USA. 1988;85:9456-9460 (Pubitemid 19027150)
    • (1988) Proceedings of the National Academy of Sciences of the United States of America , vol.85 , Issue.24 , pp. 9456-9460
    • Sakai, M.1    Okuda, A.2    Muramatsu, M.3
  • 16
    • 0024463596 scopus 로고
    • Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene
    • Okuda A, Imagawa M, Maeda Y, Sakai M, Muramatsu M. Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene. J Biol Chem. 1989;264:16919-16926 (Pubitemid 19243597)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.28 , pp. 16919-16926
    • Okuda, A.1    Imagawa, M.2    Maeda, Y.3    Sakai, M.4    Muramatsu, M.5
  • 17
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
    • DOI 10.1016/0092-8674(87)90611-8
    • Angel P, Imagawa M, Chiu R, Stein B, Imbra RJ, Rahmsdorf HJ, Jonat C, Herrlich P, Karin M. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell. 1987;49:729-739 (Pubitemid 18094763)
    • (1987) Cell , vol.49 , Issue.6 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 18
    • 2942746263 scopus 로고    scopus 로고
    • Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis
    • DOI 10.1042/BJ20031948
    • Ikeda H, Nishi S, Sakai M. Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis. Biochem J. 2004;380:515-521 (Pubitemid 38788124)
    • (2004) Biochemical Journal , vol.380 , Issue.2 , pp. 515-521
    • Ikeda, H.1    Nishi, S.2    Sakai, M.3
  • 19
    • 55449130008 scopus 로고    scopus 로고
    • Potent induction of total cellular and mitochondrial antioxidants and phase 2 enzymes by cruciferous sulforaphane in rat aortic smooth muscle cells: Cytoprotection against oxidative and electrophilic stress
    • Zhu H, Jia Z, Strobl JS, Ehrich M, Misra HP, Li Y. Potent induction of total cellular and mitochondrial antioxidants and phase 2 enzymes by cruciferous sulforaphane in rat aortic smooth muscle cells: cytoprotection against oxidative and electrophilic stress. Cardiovasc Toxicol. 2008;8:115-125
    • (2008) Cardiovasc Toxicol , vol.8 , pp. 115-125
    • Zhu, H.1    Jia, Z.2    Strobl, J.S.3    Ehrich, M.4    Misra, H.P.5    Li, Y.6
  • 20
    • 0035881570 scopus 로고    scopus 로고
    • Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines
    • Bonnesen C, Eggleston IM, Hayes JD. Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res. 2001;61:6120-6130 (Pubitemid 32762548)
    • (2001) Cancer Research , vol.61 , Issue.16 , pp. 6120-6130
    • Bonnesen, C.1    Eggleston, I.M.2    Hayes, J.D.3
  • 21
    • 33749019130 scopus 로고    scopus 로고
    • Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells
    • DOI 10.1158/0008-5472.CAN-05-3513
    • Keum YS, Yu S, Chang PP, Yuan X, Kim JH, Xu C, Han J, Agarwal A, Kong AN. Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells. Cancer Res. 2006;66:8804-8813 (Pubitemid 44449198)
    • (2006) Cancer Research , vol.66 , Issue.17 , pp. 8804-8813
    • Keum, Y.-S.1    Yu, S.2    Chang, P.P.-J.3    Yuan, X.4    Kim, J.-H.5    Xu, C.6    Han, J.7    Agarwal, A.8    Kong, A.-N.T.9
  • 22
    • 74949124720 scopus 로고    scopus 로고
    • Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture
    • Wagner AE, Ernst I, Iori R, Desel C, Rimbach G. Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture. Exp Dermatol. 2010;19:137-144
    • (2010) Exp Dermatol , vol.19 , pp. 137-144
    • Wagner, A.E.1    Ernst, I.2    Iori, R.3    Desel, C.4    Rimbach, G.5
  • 25
    • 0030768236 scopus 로고    scopus 로고
    • The pharmacology of the antioxidant lipoic acid
    • Biewenga GP, Haenen GR, Bast A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol. 1997;29:315-331
    • (1997) Gen Pharmacol , vol.29 , pp. 315-331
    • Biewenga, G.P.1    Haenen, G.R.2    Bast, A.3
  • 26
    • 41049113671 scopus 로고    scopus 로고
    • Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: Protection against neurotoxicant-elicited cytotoxicity
    • DOI 10.1007/s11064-007-9496-5
    • Jia Z, Hallur S, Zhu H, Li Y, Misra HP. Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity. Neurochem Res. 2008;33:790-800. (Pubitemid 351423143)
    • (2008) Neurochemical Research , vol.33 , Issue.5 , pp. 790-800
    • Jia, Z.1    Hallur, S.2    Zhu, H.3    Li, Y.4    Misra, H.P.5
  • 27
    • 54049130826 scopus 로고    scopus 로고
    • Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells
    • Elangovan S, Hsieh TC. Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells. Int J Oncol. 2008;33:833-838
    • (2008) Int J Oncol , vol.33 , pp. 833-838
    • Elangovan, S.1    Hsieh, T.C.2
  • 28
    • 31544448252 scopus 로고    scopus 로고
    • Garlic organosulfur compounds upregulate the expression of the pi class of glutathione S-transferase in rat primary hepatocytes
    • Tsai CW, Yang JJ, Chen HW, Sheen LY, Lii CK. Garlic organosulfur compounds upregulate the expression of the pi class of glutathione S-transferase in rat primary hepatocytes. J Nutr. 2005;135:2560-2565 (Pubitemid 43156595)
    • (2005) Journal of Nutrition , vol.135 , Issue.11 , pp. 2560-2565
    • Tsai, C.-W.1    Yang, J.-J.2    Chen, H.-W.3    Sheen, L.-Y.4    Lii, C.-K.5
  • 29
    • 34247855058 scopus 로고    scopus 로고
    • Diallyl disulfide and diallyl trisulfide up-regulate the expression of the pi class of glutathione S-transferase via an AP-1-dependent pathway
    • Tsai CW, Chen HW, Yang JJ, Sheen LY, Lii CK. Diallyl disulfide and diallyl trisulfide up-regulate the expression of the pi class of glutathione S-transferase via an AP-1-dependent pathway. J Agric Food Chem. 2007;55:1019-1026
    • (2007) J Agric Food Chem , vol.55 , pp. 1019-1026
    • Tsai, C.W.1    Chen, H.W.2    Yang, J.J.3    Sheen, L.Y.4    Lii, C.K.5
  • 30
    • 0037116438 scopus 로고    scopus 로고
    • Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats
    • Wu CC, Sheen LY, Chen HW, Kuo WW, Tsai SJ, Lii CK. Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats. J Agric Food Chem. 2002;50:378-383
    • (2002) J Agric Food Chem , vol.50 , pp. 378-383
    • Wu, C.C.1    Sheen, L.Y.2    Chen, H.W.3    Kuo, W.W.4    Tsai, S.J.5    Lii, C.K.6
  • 31
    • 0035710433 scopus 로고    scopus 로고
    • Real-time PCR analysis of DNA and RNA extracted from formalin-fixed and paraffin-embedded biopsies
    • DOI 10.1006/meth.2001.1263
    • Lehmann U, Kreipe H. Real-time PCR analysis of DNA and RNA extracted from formalin-fixed and paraffin-embedded biopsies. Methods. 2001;25:409-418 (Pubitemid 34164013)
    • (2001) Methods , vol.25 , Issue.4 , pp. 409-418
    • Lehmann, U.1    Kreipe, H.2
  • 32
    • 0000107746 scopus 로고
    • Identification of three classes of cytosolic glutathione transferase common to several mammalian species: Correlation between structural data and enzymatic properties
    • Mannervik B, Alin P, Guthenberg C, Jensson H, Tahir MK, Warholm M, Jornvall H. Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci USA. 1985;82:7202-7206
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7202-7206
    • Mannervik, B.1    Alin, P.2    Guthenberg, C.3    Jensson, H.4    Tahir, M.K.5    Warholm, M.6    Jornvall, H.7
  • 33
    • 33947381094 scopus 로고    scopus 로고
    • NAD(P)H:Quinone oxidoreductase 1 and nrh: Quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:Quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism
    • Jamieson D, Wilson K, Pridgeon S, Margetts JP, Edmondson RJ, Leung HY, Knox R, Boddy AV. NAD(P)H:quinone oxidoreductase 1 and nrh: quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism. Clin Cancer Res. 2007;13:1584-1590
    • (2007) Clin Cancer Res , vol.13 , pp. 1584-1590
    • Jamieson, D.1    Wilson, K.2    Pridgeon, S.3    Margetts, J.P.4    Edmondson, R.J.5    Leung, H.Y.6    Knox, R.7    Boddy, A.V.8
  • 34
    • 0033037686 scopus 로고    scopus 로고
    • Drug metabolism polymorphisms as modulators of cancer susceptibility
    • Taningher M, Malacarne D, Izzotti A, Ugolini D, Parodi S. Drug metabolism polymorphisms as modulators of cancer susceptibility. Mutat Res. 1999;436:227-261
    • (1999) Mutat Res , vol.436 , pp. 227-261
    • Taningher, M.1    Malacarne, D.2    Izzotti, A.3    Ugolini, D.4    Parodi, S.5
  • 35
    • 0030589723 scopus 로고    scopus 로고
    • Glutathione S-transferases of female A/J mouse liver and forestomach and their differential induction by anti-carcinogenic organosulfides from garlic
    • Hu X, Benson PJ, Srivastava SK, Mack LM, Xia H, Gupta V, Zaren HA, Singh SV. Glutathione S-transferases of female A/J mouse liver and forestomach and their differential induction by anti-carcinogenic organosulfides from garlic. Arch Biochem Biophys. 1996;336:199-214.
    • (1996) Arch Biochem Biophys , vol.336 , pp. 199-214
    • Hu, X.1    Benson, P.J.2    Srivastava, S.K.3    Mack, L.M.4    Xia, H.5    Gupta, V.6    Zaren, H.A.7    Singh, S.V.8
  • 36
    • 33746559210 scopus 로고    scopus 로고
    • Garlic allyl sulfides display differential modulation of rat cytochrome P450 2B1 and the placental form glutathione S-transferase in various organs
    • Lii CK, Tsai CW, Wu CC. Garlic allyl sulfides display differential modulation of rat cytochrome P450 2B1 and the placental form glutathione S-transferase in various organs. J Agric Food Chem. 2006;54:5191-5196
    • (2006) J Agric Food Chem , vol.54 , pp. 5191-5196
    • Lii, C.K.1    Tsai, C.W.2    Wu, C.C.3
  • 37
    • 31344458328 scopus 로고    scopus 로고
    • Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells
    • Cherng SH, Hsu SL, Yang JL, Yu CT, Lee H. Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells. Toxicol Lett. 2006;161:236-243
    • (2006) Toxicol Lett , vol.161 , pp. 236-243
    • Cherng, S.H.1    Hsu, S.L.2    Yang, J.L.3    Yu, C.T.4    Lee, H.5
  • 38
    • 0035123176 scopus 로고    scopus 로고
    • Pharmacologic activities of aged garlic extract in comparison with other garlic preparations
    • Kasuga S, Uda N, Kyo E, Ushijima M, Morihara N, Itakura Y. Pharmacologic activities of aged garlic extract in comparison with other garlic preparations. J Nutr. 2001;131:S1080-4.
    • (2001) J Nutr , vol.131
    • Kasuga, S.1    Uda, N.2    Kyo, E.3    Ushijima, M.4    Morihara, N.5    Itakura, Y.6
  • 39
    • 0025273736 scopus 로고
    • Functional cooperativity between two TPA responsive elements in undifferentiated F9 embryonic stem cells
    • Okuda A, Imagawa M, Sakai M, Muramatsu M. Functional cooperativity between two TPA responsive elements in undifferentiated F9 embryonic stem cells. EMBO J. 1990;9:1131-1135
    • (1990) EMBO J , vol.9 , pp. 1131-1135
    • Okuda, A.1    Imagawa, M.2    Sakai, M.3    Muramatsu, M.4
  • 40
    • 0034646646 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins as potential inducers of phase II detoxification enzymes. 15-deoxy-delta (12,14)-prostaglandin j2-induced expression of glutathione S-transferases
    • Kawamoto Y, Nakamura Y, Naito Y, Torii Y, Kumagai T, Osawa T, Ohigashi H, Satoh K, Imagawa M, et al. Cyclopentenone prostaglandins as potential inducers of phase II detoxification enzymes. 15-deoxy-delta (12,14)-prostaglandin j2-induced expression of glutathione S-transferases. J Biol Chem. 2000;275:11291-11299
    • (2000) J Biol Chem , vol.275 , pp. 11291-11299
    • Kawamoto, Y.1    Nakamura, Y.2    Naito, Y.3    Torii, Y.4    Kumagai, T.5    Osawa, T.6    Ohigashi, H.7    Satoh, K.8    Imagawa, M.9
  • 44
    • 0032542213 scopus 로고    scopus 로고
    • Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes
    • Venugopal R, Jaiswal AK. Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes. Oncogene. 1998;17:3145-3156
    • (1998) Oncogene , vol.17 , pp. 3145-3156
    • Venugopal, R.1    Jaiswal, A.K.2
  • 45
    • 70249087960 scopus 로고    scopus 로고
    • The role of c-Jun phosphorylation in EpRE activation of phase II genes
    • Levy S, Jaiswal AK, Forman HJ. The role of c-Jun phosphorylation in EpRE activation of phase II genes. Free Radic Biol Med. 2009;47:1172-1179
    • (2009) Free Radic Biol Med , vol.47 , pp. 1172-1179
    • Levy, S.1    Jaiswal, A.K.2    Forman, H.J.3
  • 46
    • 69249230784 scopus 로고    scopus 로고
    • Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element
    • Shenvi SV, Smith EJ, Hagen TM. Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element. Pharmacol Res. 2009;60:229-236
    • (2009) Pharmacol Res , vol.60 , pp. 229-236
    • Shenvi, S.V.1    Smith, E.J.2    Hagen, T.M.3
  • 47
    • 3142721782 scopus 로고    scopus 로고
    • Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage
    • Gao X, Talalay P. Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proc Natl Acad Sci USA. 2004;101:10446-10451
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10446-10451
    • Gao, X.1    Talalay, P.2
  • 48
    • 33846300705 scopus 로고    scopus 로고
    • Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract
    • Ritz SA, Wan J, Diaz-Sanchez D. Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract. Am J Physiol Lung Cell Mol Physiol. 2007;292:L33-9.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Ritz, S.A.1    Wan, J.2    Diaz-Sanchez, D.3
  • 49
    • 0037188518 scopus 로고    scopus 로고
    • Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors
    • Fahey JW, Haristoy X, Dolan PM, Kensler TW, Scholtus I, Stephenson KK, Talalay P, Lozniewski A. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors. Proc Natl Acad Sci USA. 2002;99:7610-7615
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7610-7615
    • Fahey, J.W.1    Haristoy, X.2    Dolan, P.M.3    Kensler, T.W.4    Scholtus, I.5    Stephenson, K.K.6    Talalay, P.7    Lozniewski, A.8
  • 50
    • 1042290476 scopus 로고    scopus 로고
    • (R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: Evidence for increased cysteine requirement for GSH synthesis
    • Suh JH, Wang H, Liu RM, Liu J, Hagen TM. (R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis. Arch Biochem Biophys. 2004;423:126-135
    • (2004) Arch Biochem Biophys , vol.423 , pp. 126-135
    • Suh, J.H.1    Wang, H.2    Liu, R.M.3    Liu, J.4    Hagen, T.M.5
  • 51
    • 58049176800 scopus 로고    scopus 로고
    • Antioxidant properties of alphalipoic acid: Effects on red blood membrane permeability and adaptation of isolated rat heart to reversible ischemia
    • Ghibu S, Lauzier B, Delemasure S, Amoureux S, Sicard P, Vergely C, Muresan A, Mogosan C, Rochette L. Antioxidant properties of alphalipoic acid: effects on red blood membrane permeability and adaptation of isolated rat heart to reversible ischemia. Mol Cell Biochem. 2009;320:141-148
    • (2009) Mol Cell Biochem , vol.320 , pp. 141-148
    • Ghibu, S.1    Lauzier, B.2    Delemasure, S.3    Amoureux, S.4    Sicard, P.5    Vergely, C.6    Muresan, A.7    Mogosan, C.8    Rochette, L.9
  • 52
    • 34249039316 scopus 로고    scopus 로고
    • Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain
    • Bilska A, Dubiel M, Sokolowska-Jezewicz M, Lorenc-Koci E, Wlodek L. Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain. Neuroscience. 2007;146:1758-1771
    • (2007) Neuroscience , vol.146 , pp. 1758-1771
    • Bilska, A.1    Dubiel, M.2    Sokolowska-Jezewicz, M.3    Lorenc-Koci, E.4    Wlodek, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.