Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells

Toxicology Letters

Volumn 201, Issue 3, 2011, Pages 240-248

  Lee, Seung Eun ^a   Jeong, Seong Il ^a   Kim, Gun Dong ^a   Yang, Hana ^a   Park, Cheung Seog ^a   Jin, Young Ho ^a   Park, Yong Seek ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

Crotonaldehyde; Endothelial cells; HO 1; Oxidative stress

Indexed keywords

CIGARETTE SMOKE; CROTONALDEHYDE; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C DELTA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2;

APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INDUCTION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RISK FACTOR;

ADAPTATION, PHYSIOLOGICAL; ALDEHYDES; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HEME OXYGENASE-1; HUMANS; LUCIFERASES; NF-E2-RELATED FACTOR 2; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; PROTEIN KINASE C-DELTA; REACTIVE OXYGEN SPECIES; RNA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; UMBILICAL VEINS; UP-REGULATION;

EID: 79951767414     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.01.006     Document Type: Article

References (54)

1. Abraham N.G., Kappas A. Heme oxygenase and the cardiovascular-renal system. Free Radic. Biol. Med. 2005, 39:1-25.
2. Alvarez-Maqueda M., El Bekay R., Alba G., Monteseirin J., Chacon P., Vega A., Martin-Nieto J., Bedoya F.J., Pintado E., Sobrino F. 15-Deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. J. Biol. Chem. 2004, 279:21929-21937.
3. Balogun E., Hoque M., Gong P., Killeen E., Green C.J., Foresti R., Alam J., Motterlini R. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem. J. 2003, 371:887-895.
4. Bittersohl G. Epidemiologic investigations on cancer incidence in workers contacted by acetaldol and other aliphatic aldehyds (author's transl). Arch. Geschwulstforsch. 1974, 43:172-176.
5. Brouard S., Otterbein L.E., Anrather J., Tobiasch E., Bach F.H., Choi A.M., Soares M.P. Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J. Exp. Med. 2000, 192:1015-1026.
6. 2-induced apoptosis through functional codependence between HO-1 and AKT. Arterioscler. Thromb. Vasc. Biol. 2006, 26:2027-2034.
7. Buckley B.J., Marshall Z.M., Whorton A.R. Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium. Biochem. Biophys. Res. Commun. 2003, 307:973-979.
8. Budiawan, Eder E. Detection of 1,N(2)-propanodeoxyguanosine adducts in DNA of Fischer 344 rats by an adapted (32)P-post-labeling technique after per os application of crotonaldehyde. Carcinogenesis 2000, 21:1191-1196.
9. Chen P.X., Moldoveanu S.C. Mainstream smoke chemical analyses for 2R4F Kentucky reference cigarette. Beiträge zur Tabakforschung International 2003, 20:448-458.
10. Choi B.M., Kim Y.M., Jeong Y.R., Pae H.O., Song C.E., Park J.E., Ahn Y.K., Chung H.T. Induction of heme oxygenase-1 is involved in anti-proliferative effects of paclitaxel on rat vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 2004, 321:132-137.
11. Chung F.L., Tanaka T., Hecht S.S. Induction of liver tumors in F344 rats by crotonaldehyde. Cancer Res. 1986, 46:1285-1289.
12. Cullinan S.B., Diehl J.A. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J. Biol. Chem. 2004, 279:20108-20117.
13. Czerny C., Eder E., Runger T.M. Genotoxicity and mutagenicity of the alpha, beta-unsaturated carbonyl compound crotonaldehyde (butenal) on a plasmid shuttle vector. Mutat. Res. 1998, 407:125-134.
14. Dong J.Z., Moldoveanu S.C. Gas chromatography-mass spectrometry of carbonyl compounds in cigarette mainstream smoke after derivatization with 2,4-dinitrophenylhydrazine. J. Chromatogr. A 2004, 1027:25-35.
15. Eder E., Schuler D., Budiawan Cancer Risk Assessment for Crotonaldehyde and 2-Hexenal: An Approach 1999, IARC Scientific Publications, pp. 219-232.
16. Eiserich J.P., van der Vliet A., Handelman G.J., Halliwell B., Cross C.E. Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction. Am. J. Clin. Nutr. 1995, 62:1490S-1500S.
17. Elbaz A., Wei Y.Y., Meng Q., Zheng Q., Yang Z.M. Mercury-induced oxidative stress and impact on antioxidant enzymes in Chlamydomonas reinhardtii. Ecotoxicology 2010.
18. Esterbauer H., Schaur R.J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 1991, 11:81-128.
19. Facchinetti F., Amadei F., Geppetti P., Tarantini F., Di Serio C., Dragotto A., Gigli P.M., Catinella S., Civelli M., Patacchini R. Alpha, beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages. Am. J. Respir. Cell Mol. Biol. 2007, 37:617-623.
20. Fernandes P.H., Kanuri M., Nechev L.V., Harris T.M., Lloyd R.S. Mammalian cell mutagenesis of the DNA adducts of vinyl chloride and crotonaldehyde. Environ. Mol. Mutagen. 2005, 45:455-459.
21. Hill M., Pereira V., Chauveau C., Zagani R., Remy S., Tesson L., Mazal D., Ubillos L., Brion R., Asghar K., Mashreghi M.F., Kotsch K., Moffett J., Doebis C., Seifert M., Boczkowski J., Osinaga E., Anegon I. Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. FASEB J. 2005, 19:1957-1968.
22. Huang H.C., Nguyen T., Pickett C.B. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J. Biol. Chem. 2002, 277:42769-42774.
23. IARC Crotonaldehyde. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans/World Health Organization 1995, vol. 63. International Agency for Research on Cancer, pp. 373-391.
24. Itoh K., Tong K.I., Yamamoto M. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic. Biol. Med. 2004, 36:1208-1213.
25. Jadhav A., Torlakovic E., Ndisang J.F. Hemin therapy attenuates kidney injury in deoxycorticosterone acetate-salt hypertensive rats. Am. J. Physiol. Renal Physiol. 2009, 296:F521-F534.
26. Kawaguchi-Niida M., Shibata N., Morikawa S., Uchida K., Yamamoto T., Sawada T., Kobayashi M. Crotonaldehyde accumulates in glial cells of Alzheimer's disease brain. Acta Neuropathol. 2006, 111:422-429.
27. Kensler T.W., Wakabayashi N., Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 2007, 47:89-116.
28. Kobayashi M., Yamamoto M. Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid. Redox Signal. 2005, 7:385-394.
29. Lee N.J., Lee S.E., Lee S.H., Ryu D.S., Park Y.S. Acrolein induces adaptive response through upregulate of HO-1 via activation of Nrf2 in RAW 264.7 macrophage. Mol. Cell. Toxicol. 2009, 5:77-177.
30. Lee S.E., Lee N.J., Lee S.H., Park C.S., Ahn H.J., Park Y.S. Uncaria rhynchophylla induces heme oxygenase-1 as a cytoprotective effect in RAW 264.7 macrophages. Mol. Cell. Toxicol. 2010, 6:33-40.
31. Lee S.H., Lee S.E., Ahn H.-J., Park C.-S., Cho J.-J., Park Y.-S. Identification of atherosclerosis related gene expression profiles by treatment of benzo(a)pyrene in human umbilical vein endothelial cells. Mol. Cell. Toxicol. 2009, 5:113-119.
32. Lee T.S., Chau L.Y. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med. 2002, 8:240-246.
33. Li M.H., Cha Y.N., Surh Y.J. Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Free Radic. Biol. Med. 2006, 41:1079-1091.
34. Liu H., Nowak R., Chao W., Bloch K.D. Nerve growth factor induces anti-apoptotic heme oxygenase-1 in rat pheochromocytoma PC12 cells. J. Neurochem. 2003, 86:1553-1563.
35. Liu X.Y., Yang Z.H., Pan X.J., Zhu M.X., Xie J.P. Crotonaldehyde induces oxidative stress and caspase-dependent apoptosis in human bronchial epithelial cells. Toxicol. Lett. 2010, 195:90-98.
36. Liu X.Y., Yang Z.H., Pan X.J., Zhu M.X., Xie J.P. Gene expression profile and cytotoxicity of human bronchial epithelial cells exposed to crotonaldehyde. Toxicol. Lett. 2010, 197:113-122.
37. Luczaj W., Skrzydlewska E. DNA damage caused by lipid peroxidation products. Cell. Mol. Biol. Lett. 2003, 8:391-413.
38. Martin D., Rojo A.I., Salinas M., Diaz R., Gallardo G., Alam J., De Galarreta C.M., Cuadrado A. Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J. Biol. Chem. 2004, 279:8919-8929.
39. McNally S.J., Harrison E.M., Ross J.A., Garden O.J., Wigmore S.J. Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition. Int. J. Mol. Med. 2007, 19:165-172.
40. Neudecker T., Eder E., Deininger C., Henschler D. Crotonaldehyde is mutagenic in Salmonella typhimurium TA100. Environ. Mol. Mutagen. 1989, 14:146-148.
41. Park Y.S., Misonou Y., Fujiwara N., Takahashi M., Miyamoto Y., Koh Y.H., Suzuki K., Taniguchi N. Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 2005, 327:1058-1065.
42. Petrache I., Otterbein L.E., Alam J., Wiegand G.W., Choi A.M. Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts. Am. J. Physiol. Lung Cell Mol. Physiol. 2000, 278:L312-L319.
43. Reddy S., Finkelstein E.I., Wong P.S., Phung A., Cross C.E., van der Vliet A. Identification of glutathione modifications by cigarette smoke. Free Radic. Biol. Med. 2002, 33:1490-1498.
44. Rushworth S.A., Chen X.L., Mackman N., Ogborne R.M., O'Connell M.A. Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C. J. Immunol. 2005, 175:4408-4415.
45. Ryter S.W., Alam J., Choi A.M. Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol. Rev. 2006, 86:583-650.
46. Scott J.R., Cukiernik M.A., Ott M.C., Bihari A., Badhwar A., Gray D.K., Harris K.A., Parry N.G., Potter R.F. Low-dose inhaled carbon monoxide attenuates the remote intestinal inflammatory response elicited by hindlimb ischemia-reperfusion. Am. J. Physiol. Gastrointest. Liver Physiol. 2009, 296:G9-G14.
47. Simon S.A., Liedtke W. How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. J. Clin. Invest. 2008, 118:2383-2386.
48. So H.S., Kim H.J., Lee J.H., Lee J.H., Park S.Y., Park C., Kim Y.H., Kim J.K., Lee K.M., Kim K.S., Chung S.Y., Jang W.C., Moon S.K., Chung H.T., Park R.K. Flunarizine induces Nrf2-mediated transcriptional activation of heme oxygenase-1 in protection of auditory cells from cisplatin. Cell Death Differ. 2006, 13:1763-1775.
49. Stein S., Lao Y., Yang I.Y., Hecht S.S., Moriya M. Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells. Mutat. Res. 2006, 608:1-7.
50. Ueda K., Ueyama T., Yoshida K., Kimura H., Ito T., Shimizu Y., Oka M., Tsuruo Y., Ichinose M. Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions. Am. J. Physiol. Gastrointest. Liver Physiol. 2008, 295:G460-G469.
51. Vermes I., Haanen C., Steffens-Nakken H., Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J. Immunol. Methods 1995, 184:39-51.
52. Willis D., Moore A.R., Frederick R., Willoughby D.A. Heme oxygenase: a novel target for the modulation of the inflammatory response. Nat. Med. 1996, 2:87-90.
53. Zhang H., Forman H.J. Acrolein induces heme oxygenase-1 through PKC-delta and PI3K in human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 2008, 38:483-490.
54. Zhang H., Forman H.J. Signaling pathways involved in phase II gene induction by alpha, beta-unsaturated aldehydes. Toxicol. Ind. Health 2009, 25:269-278.