Xanthohumol isolated from Humulus lupulus inhibits menadione-induced DNA damage through induction of quinone reductase

Chemical Research in Toxicology

Volumn 18, Issue 8, 2005, Pages 1296-1305

  Dietz, Birgit M ^a   Kang, Young Hwa ^a   Liu, Guowen ^a   Eggler, Aimee L ^a   Yao, Ping ^a   Chadwick, Lucas R ^a   Pauli, Guido F ^a   Farnsworth, Norman R ^a   Mesecar, Andrew D ^a   Van Breemen, Richard B ^a   Bolton, Judy L ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 8 PRENYLNARINGENIN; CHALCONE DERIVATIVE; CYSTEINE; DICOUMAROL; DNA; FREE RADICAL; HUMULUS LUPULUS EXTRACT; MENADIONE; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; XANTHOHUMOL;

ALKYLATION; ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA DAMAGE; DOSE RESPONSE; DRUG EFFICACY; ENZYME INDUCTION; GEL ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMULUS LUPULUS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN EXPRESSION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALKYLATION; ANIMALS; ANTIOXIDANTS; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; CELL SURVIVAL; CYTOSKELETAL PROTEINS; DICUMAROL; DNA DAMAGE; ENZYME INDUCTION; GENES, REPORTER; HUMULUS; HYDRAZINES; LUCIFERASES; MICE; NAD(P)H DEHYDROGENASE (QUINONE); PLANT EXTRACTS; PROPIOPHENONES; PROTEIN ISOPRENYLATION; RESPONSE ELEMENTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VITAMIN K 3;

HUMULUS LUPULUS;

EID: 23844553151     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx050058x     Document Type: Article

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