Linalool decreases HepG2 viability by inhibiting mitochondrial complexes I and II, increasing reactive oxygen species and decreasing ATP and GSH levels

Chemico-Biological Interactions

Volumn 180, Issue 1, 2009, Pages 39-46

  Usta, Julnar ^a   Kreydiyyeh, Sawsan ^a   Knio, Khuzama ^a   Barnabe, Pascale ^a   Bou Moughlabay, Yolla ^a   Dagher, Shawki ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

Complex I; Complex II; Flavonoids; GSH; HepG2; Linalool; NAC; ROS

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; APIGENIN; ESSENTIAL OIL; FLAVONOID; GLUTATHIONE; LINALOOL; MYRCENE; NEROLIDOL; NITROBLUE TETRAZOLIUM; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; RUTOSIDE; TROLOX C;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL STRAIN 3T3; CELL STRAIN HEK293; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CELL VIABILITY; COMPETITIVE INHIBITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORIANDER; CYTOTOXICITY; DISTILLATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MASS FRAGMENTOGRAPHY; MITOCHONDRION; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; RAT; RESPIRATORY CHAIN;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE; CELL SURVIVAL; CORIANDRUM; DOWN-REGULATION; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; GLUTATHIONE; INSECTICIDES; LIVER; MITOCHONDRIA; MOLECULAR STRUCTURE; MONOTERPENES; PLANT PREPARATIONS; RATS; REACTIVE OXYGEN SPECIES; SEEDS;

CORIANDRUM SATIVUM;

EID: 67349093523     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.02.012     Document Type: Article

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