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Volumn 46, Issue 6, 2011, Pages 441-452

The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation

Author keywords

Aging; C. elegans; Diallyl trisulfide; Garlic; Gst 4; Microarray; Skn 1

Indexed keywords

DIALLYL TRISULFIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GST 4; TRANSCRIPTION FACTOR SKN 1; UNCLASSIFIED DRUG;

EID: 79955632661     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2011.01.005     Document Type: Article
Times cited : (68)

References (80)
  • 3
    • 0042626242 scopus 로고    scopus 로고
    • SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response
    • An J.H., Blackwell T.K. SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response. Genes Dev. 2003, 17:1882-1893.
    • (2003) Genes Dev. , vol.17 , pp. 1882-1893
    • An, J.H.1    Blackwell, T.K.2
  • 4
    • 28044446334 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3
    • An J.H., Vranas K., Lucke M., Inoue H., Hisamoto N., Matsumoto K., Blackwell T.K. Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3. Proc. Natl Acad. Sci. USA 2005, 102:16275-16280.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 16275-16280
    • An, J.H.1    Vranas, K.2    Lucke, M.3    Inoue, H.4    Hisamoto, N.5    Matsumoto, K.6    Blackwell, T.K.7
  • 5
    • 0025533067 scopus 로고
    • Chemosensory cell function in the behavior and development of Caenorhabditis elegans
    • Bargmann C.I., Thomas J.H., Horvitz H.R. Chemosensory cell function in the behavior and development of Caenorhabditis elegans. Cold Spring Harb. Symp. Quant. Biol. 1990, 55:529-538.
    • (1990) Cold Spring Harb. Symp. Quant. Biol. , vol.55 , pp. 529-538
    • Bargmann, C.I.1    Thomas, J.H.2    Horvitz, H.R.3
  • 6
    • 34249891333 scopus 로고    scopus 로고
    • Two neurons mediate diet-restriction-induced longevity in C. elegans
    • Bishop N.A., Guarente L. Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 2007, 447:545-549.
    • (2007) Nature , vol.447 , pp. 545-549
    • Bishop, N.A.1    Guarente, L.2
  • 7
    • 0022039421 scopus 로고
    • The chemistry of garlic and onions
    • Block E. The chemistry of garlic and onions. Sci. Am. 1985, 252:114-119.
    • (1985) Sci. Am. , vol.252 , pp. 114-119
    • Block, E.1
  • 8
    • 0031859142 scopus 로고    scopus 로고
    • Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease
    • Bordia A., Verma S.K., Srivastava K.C. Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. Prostaglandins Leukot. Essent. Fatty Acids 1998, 58:257-263.
    • (1998) Prostaglandins Leukot. Essent. Fatty Acids , vol.58 , pp. 257-263
    • Bordia, A.1    Verma, S.K.2    Srivastava, K.C.3
  • 9
    • 0042636915 scopus 로고    scopus 로고
    • Protective effect of chronic garlic intake on elastic properties of aorta in the elderly
    • Breithaupt-Grogler K., Ling M., Boudoulas H., Belz G.G. Protective effect of chronic garlic intake on elastic properties of aorta in the elderly. Circulation 1997, 96:2649-2655.
    • (1997) Circulation , vol.96 , pp. 2649-2655
    • Breithaupt-Grogler, K.1    Ling, M.2    Boudoulas, H.3    Belz, G.G.4
  • 10
    • 5344220933 scopus 로고    scopus 로고
    • Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals
    • Chen C., Pung D., Leong V., Hebbar V., Shen G., Nair S., Li W., Kong A.N. Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals. Free Radic. Biol. Med. 2004, 37:1578-1590.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 1578-1590
    • Chen, C.1    Pung, D.2    Leong, V.3    Hebbar, V.4    Shen, G.5    Nair, S.6    Li, W.7    Kong, A.N.8
  • 11
    • 66349105688 scopus 로고    scopus 로고
    • The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans
    • Choe K.P., Przybysz A.J., Strange K. The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans. Mol. Cell. Biol. 2009, 29:2704-2715.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 2704-2715
    • Choe, K.P.1    Przybysz, A.J.2    Strange, K.3
  • 13
    • 66149087761 scopus 로고    scopus 로고
    • A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans
    • Cristina D., Cary M., Lunceford A., Clarke C., Kenyon C. A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans. PLoS Genet. 2009, 5:e1000450.
    • (2009) PLoS Genet. , vol.5
    • Cristina, D.1    Cary, M.2    Lunceford, A.3    Clarke, C.4    Kenyon, C.5
  • 14
    • 0037174629 scopus 로고    scopus 로고
    • Timing requirements for insulin/IGF-1 signaling in C. elegans
    • Dillin A., Crawford D.K., Kenyon C. Timing requirements for insulin/IGF-1 signaling in C. elegans. Science 2002, 298:830-834.
    • (2002) Science , vol.298 , pp. 830-834
    • Dillin, A.1    Crawford, D.K.2    Kenyon, C.3
  • 15
    • 0036616938 scopus 로고    scopus 로고
    • Effects of garlic extract on oxidant/antioxidant status and atherosclerotic plaque formation in rabbit aorta
    • Durak I., Ozturk H.S., Olcay E., Can B., Kavutcu M. Effects of garlic extract on oxidant/antioxidant status and atherosclerotic plaque formation in rabbit aorta. Nutr. Metab. Cardiovasc. Dis. 2002, 12:141-147.
    • (2002) Nutr. Metab. Cardiovasc. Dis. , vol.12 , pp. 141-147
    • Durak, I.1    Ozturk, H.S.2    Olcay, E.3    Can, B.4    Kavutcu, M.5
  • 16
    • 44449132586 scopus 로고    scopus 로고
    • Effect of garlic on atherosclerosis and its factors
    • El-Sabban F., Abouazra H. Effect of garlic on atherosclerosis and its factors. East. Mediterr. Health J. 2008, 14:195-205.
    • (2008) East. Mediterr. Health J. , vol.14 , pp. 195-205
    • El-Sabban, F.1    Abouazra, H.2
  • 17
    • 0029166896 scopus 로고
    • Identification genes that are differentially expressed during aging in Caenorhabditis elegans
    • Fabian T.J., Johnson T.E. Identification genes that are differentially expressed during aging in Caenorhabditis elegans. J. Gerontol. Biol. Sci. Med. Sci. 1995, 50:B245-B253.
    • (1995) J. Gerontol. Biol. Sci. Med. Sci. , vol.50
    • Fabian, T.J.1    Johnson, T.E.2
  • 18
    • 33646908532 scopus 로고    scopus 로고
    • The nuclear hormone receptor DAF-12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long-lived worms
    • Fisher A.L., Lithgow G.J. The nuclear hormone receptor DAF-12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long-lived worms. Aging Cell 2006, 5:127-138.
    • (2006) Aging Cell , vol.5 , pp. 127-138
    • Fisher, A.L.1    Lithgow, G.J.2
  • 19
    • 44049105102 scopus 로고    scopus 로고
    • The Caenorhabditis elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family: a Caenorhabditis elegans model of type I tyrosinemia
    • Fisher A.L., Page K.E., Lithgow G.J., Nash L. The Caenorhabditis elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family: a Caenorhabditis elegans model of type I tyrosinemia. J. Biol. Chem. 2008, 283:9127-9135.
    • (2008) J. Biol. Chem. , vol.283 , pp. 9127-9135
    • Fisher, A.L.1    Page, K.E.2    Lithgow, G.J.3    Nash, L.4
  • 20
    • 0032812158 scopus 로고    scopus 로고
    • Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China
    • Gao C.M., Takezaki T., Ding J.H., Li M.S., Tajima K. Protective effect of allium vegetables against both esophageal and stomach cancer: a simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China. Jpn J. Cancer Res. 1999, 90:614-621.
    • (1999) Jpn J. Cancer Res. , vol.90 , pp. 614-621
    • Gao, C.M.1    Takezaki, T.2    Ding, J.H.3    Li, M.S.4    Tajima, K.5
  • 21
    • 0035178052 scopus 로고    scopus 로고
    • The effect of a garlic preparation on plasma lipid levels in moderately hypercholesterolemic adults
    • Gardner C.D., Chatterjee L.M., Carlson J.J. The effect of a garlic preparation on plasma lipid levels in moderately hypercholesterolemic adults. Atherosclerosis 2001, 154:213-220.
    • (2001) Atherosclerosis , vol.154 , pp. 213-220
    • Gardner, C.D.1    Chatterjee, L.M.2    Carlson, J.J.3
  • 22
    • 33847339289 scopus 로고    scopus 로고
    • Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial
    • Gardner C.D., Lawson L.D., Block E., Chatterjee L.M., Kiazand A., Balise R.R., Kraemer H.C. Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial. Arch. Intern. Med. 2007, 167:346-353.
    • (2007) Arch. Intern. Med. , vol.167 , pp. 346-353
    • Gardner, C.D.1    Lawson, L.D.2    Block, E.3    Chatterjee, L.M.4    Kiazand, A.5    Balise, R.R.6    Kraemer, H.C.7
  • 23
    • 0036021375 scopus 로고    scopus 로고
    • Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation
    • Garigan D., Hsu A.L., Fraser A.G., Kamath R.S., Ahringer J., Kenyon C. Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 2002, 161:1101-1112.
    • (2002) Genetics , vol.161 , pp. 1101-1112
    • Garigan, D.1    Hsu, A.L.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Kenyon, C.6
  • 24
    • 0035656274 scopus 로고    scopus 로고
    • A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span
    • Gerisch B., Weitzel C., Kober-Eisermann C., Rottiers V., Antebi A. A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Dev. Cell 2001, 1:841-851.
    • (2001) Dev. Cell , vol.1 , pp. 841-851
    • Gerisch, B.1    Weitzel, C.2    Kober-Eisermann, C.3    Rottiers, V.4    Antebi, A.5
  • 26
    • 63549108476 scopus 로고    scopus 로고
    • Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
    • Greer E.L., Brunet A. Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell 2009, 8:113-127.
    • (2009) Aging Cell , vol.8 , pp. 113-127
    • Greer, E.L.1    Brunet, A.2
  • 27
    • 0035846604 scopus 로고    scopus 로고
    • Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • Henderson S.T., Johnson T.E. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr. Biol. 2001, 11:1975-1980.
    • (2001) Curr. Biol. , vol.11 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 28
    • 48749115206 scopus 로고    scopus 로고
    • Elongation and desaturation of fatty acids are critical in growth, lipid metabolism and ontogeny of Caenorhabditis elegans
    • Horikawa M., Nomura T., Hashimoto T., Sakamoto K. Elongation and desaturation of fatty acids are critical in growth, lipid metabolism and ontogeny of Caenorhabditis elegans. J. Biochem. 2008, 144:149-158.
    • (2008) J. Biochem. , vol.144 , pp. 149-158
    • Horikawa, M.1    Nomura, T.2    Hashimoto, T.3    Sakamoto, K.4
  • 30
    • 25844490465 scopus 로고    scopus 로고
    • The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response
    • Inoue H., Hisamoto N., An J.H., Oliveira R.P., Nishida E., Blackwell T.K., Matsumoto K. The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev. 2005, 19:2278-2283.
    • (2005) Genes Dev. , vol.19 , pp. 2278-2283
    • Inoue, H.1    Hisamoto, N.2    An, J.H.3    Oliveira, R.P.4    Nishida, E.5    Blackwell, T.K.6    Matsumoto, K.7
  • 31
    • 0036333147 scopus 로고    scopus 로고
    • DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity
    • Jia K., Albert P.S., Riddle D.L. DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity. Development 2002, 129:221-231.
    • (2002) Development , vol.129 , pp. 221-231
    • Jia, K.1    Albert, P.S.2    Riddle, D.L.3
  • 32
    • 55449101207 scopus 로고    scopus 로고
    • Chromium (VI)-induced oxidative stress and apoptosis is reduced by garlic and its derivative S-allylcysteine through the activation of Nrf2 in the hepatocytes of Wistar rats
    • Kalayarasan S., Sriram N., Sureshkumar A., Sudhandiran G. Chromium (VI)-induced oxidative stress and apoptosis is reduced by garlic and its derivative S-allylcysteine through the activation of Nrf2 in the hepatocytes of Wistar rats. J. Appl. Toxicol. 2008, 28:908-919.
    • (2008) J. Appl. Toxicol. , vol.28 , pp. 908-919
    • Kalayarasan, S.1    Sriram, N.2    Sureshkumar, A.3    Sudhandiran, G.4
  • 33
    • 33845638745 scopus 로고    scopus 로고
    • Caenorhabditis elegans has two genes encoding functional d-aspartate oxidases
    • Katane M., Seida Y., Sekine M., Furuchi T., Homma H. Caenorhabditis elegans has two genes encoding functional d-aspartate oxidases. FEBS J. 2007, 274:137-149.
    • (2007) FEBS J. , vol.274 , pp. 137-149
    • Katane, M.1    Seida, Y.2    Sekine, M.3    Furuchi, T.4    Homma, H.5
  • 34
    • 35348981196 scopus 로고    scopus 로고
    • Activation of SKN-1 by novel kinases in Caenorhabditis elegans
    • Kell A., Ventura N., Kahn N., Johnson T.E. Activation of SKN-1 by novel kinases in Caenorhabditis elegans. Free Radic. Biol. Med. 2007, 43:1560-1566.
    • (2007) Free Radic. Biol. Med. , vol.43 , pp. 1560-1566
    • Kell, A.1    Ventura, N.2    Kahn, N.3    Johnson, T.E.4
  • 35
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C., Chang J., Gensch E., Rudner A., Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993, 366:461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 36
    • 0037274642 scopus 로고    scopus 로고
    • Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans
    • Kniazeva M., Sieber M., McCauley S., Zhang K., Watts J.L., Han M. Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans. Genetics 2003, 163:159-169.
    • (2003) Genetics , vol.163 , pp. 159-169
    • Kniazeva, M.1    Sieber, M.2    McCauley, S.3    Zhang, K.4    Watts, J.L.5    Han, M.6
  • 37
    • 19344363119 scopus 로고    scopus 로고
    • Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development
    • Kniazeva M., Crawford Q.T., Seiber M., Wang C.Y., Han M. Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development. PLoS Biol. 2004, 2:E257.
    • (2004) PLoS Biol. , vol.2
    • Kniazeva, M.1    Crawford, Q.T.2    Seiber, M.3    Wang, C.Y.4    Han, M.5
  • 38
    • 5144232811 scopus 로고    scopus 로고
    • Chemoprevention through the Keap1-Nrf2 signaling pathway by phase 2 enzyme inducers
    • Kwak M.K., Wakabayashi N., Kensler T.W. Chemoprevention through the Keap1-Nrf2 signaling pathway by phase 2 enzyme inducers. Mutat. Res. 2004, 555:133-148.
    • (2004) Mutat. Res. , vol.555 , pp. 133-148
    • Kwak, M.K.1    Wakabayashi, N.2    Kensler, T.W.3
  • 39
    • 0032573178 scopus 로고    scopus 로고
    • The genetics of caloric restriction in Caenorhabditis elegans
    • Lakowski B., Hekimi S. The genetics of caloric restriction in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:13091-13096.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 13091-13096
    • Lakowski, B.1    Hekimi, S.2
  • 40
    • 33644848489 scopus 로고    scopus 로고
    • Suppression of LDL oxidation by garlic compounds is a possible mechanism of cardiovascular health benefit
    • Lau B.H. Suppression of LDL oxidation by garlic compounds is a possible mechanism of cardiovascular health benefit. J. Nutr. 2006, 136:765S-768S.
    • (2006) J. Nutr. , vol.136
    • Lau, B.H.1
  • 41
    • 0035846601 scopus 로고    scopus 로고
    • Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
    • Lee R.Y., Hench J., Ruvkun G. Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Curr. Biol. 2001, 11:1950-1957.
    • (2001) Curr. Biol. , vol.11 , pp. 1950-1957
    • Lee, R.Y.1    Hench, J.2    Ruvkun, G.3
  • 43
    • 0030657540 scopus 로고    scopus 로고
    • Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • Lin K., Dorman J.B., Rodan A., Kenyon C. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 1997, 278:1319-1322.
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 44
    • 0034967720 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
    • Lin K., Hsin H., Libina N., Kenyon C. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat. Genet. 2001, 28:139-145.
    • (2001) Nat. Genet. , vol.28 , pp. 139-145
    • Lin, K.1    Hsin, H.2    Libina, N.3    Kenyon, C.4
  • 45
    • 0036279460 scopus 로고    scopus 로고
    • Reporter transgenes for study of oxidant stress in Caenorhabditis elegans
    • Link C.D., Johnson C.J. Reporter transgenes for study of oxidant stress in Caenorhabditis elegans. Meth. Enzymol. 2002, 353:497-505.
    • (2002) Meth. Enzymol. , vol.353 , pp. 497-505
    • Link, C.D.1    Johnson, C.J.2
  • 46
    • 84887212584 scopus 로고    scopus 로고
    • Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans
    • Mair W., Panowski S.H., Shaw R.J., Dillin A. Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans. PLoS ONE 2009, 4:e4535.
    • (2009) PLoS ONE , vol.4
    • Mair, W.1    Panowski, S.H.2    Shaw, R.J.3    Dillin, A.4
  • 48
    • 0042631524 scopus 로고    scopus 로고
    • Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
    • McElwee J., Bubb K., Thomas J.H. Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2003, 2:111-121.
    • (2003) Aging Cell , vol.2 , pp. 111-121
    • McElwee, J.1    Bubb, K.2    Thomas, J.H.3
  • 49
    • 7244238167 scopus 로고    scopus 로고
    • Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
    • McElwee J.J., Schuster E., Blanc E., Thomas J.H., Gems D. Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. J. Biol. Chem. 2004, 279:44533-44543.
    • (2004) J. Biol. Chem. , vol.279 , pp. 44533-44543
    • McElwee, J.J.1    Schuster, E.2    Blanc, E.3    Thomas, J.H.4    Gems, D.5
  • 52
    • 0034061472 scopus 로고    scopus 로고
    • Activities of garlic oil, garlic powder, and their diallyl constituents against Helicobacter pylori
    • O'Gara E.A., Hill D.J., Maslin D.J. Activities of garlic oil, garlic powder, and their diallyl constituents against Helicobacter pylori. Appl. Environ. Microbiol. 2000, 66:2269-2273.
    • (2000) Appl. Environ. Microbiol. , vol.66 , pp. 2269-2273
    • O'Gara, E.A.1    Hill, D.J.2    Maslin, D.J.3
  • 53
    • 31744438846 scopus 로고    scopus 로고
    • Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
    • Oh S.W., Mukhopadhyay A., Dixit B.L., Raha T., Green M.R., Tissenbaum H.A. Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nat. Genet. 2006, 38:251-257.
    • (2006) Nat. Genet. , vol.38 , pp. 251-257
    • Oh, S.W.1    Mukhopadhyay, A.2    Dixit, B.L.3    Raha, T.4    Green, M.R.5    Tissenbaum, H.A.6
  • 55
    • 77649311383 scopus 로고    scopus 로고
    • Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
    • Onken B., Driscoll M. Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PLoS ONE 2010, 5:e8758.
    • (2010) PLoS ONE , vol.5
    • Onken, B.1    Driscoll, M.2
  • 56
    • 66149175591 scopus 로고    scopus 로고
    • Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1
    • Park S.K., Tedesco P.M., Johnson T.E. Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1. Aging Cell 2009, 8:258-269.
    • (2009) Aging Cell , vol.8 , pp. 258-269
    • Park, S.K.1    Tedesco, P.M.2    Johnson, T.E.3
  • 57
    • 43249101846 scopus 로고    scopus 로고
    • Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs
    • Patel R., Maru G. Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs. Free Radic. Biol. Med. 2008, 44:1897-1911.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 1897-1911
    • Patel, R.1    Maru, G.2
  • 58
    • 51349109112 scopus 로고    scopus 로고
    • Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds
    • Powolny A.A., Singh S.V. Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds. Cancer Lett. 2008, 269:305-314.
    • (2008) Cancer Lett. , vol.269 , pp. 305-314
    • Powolny, A.A.1    Singh, S.V.2
  • 59
    • 0028871952 scopus 로고
    • Interacting genes required for pharyngeal excitation by motor neuron MC in Caenorhabditis elegans
    • Raizen D.M., Lee R.Y., Avery L. Interacting genes required for pharyngeal excitation by motor neuron MC in Caenorhabditis elegans. Genetics 1995, 141:1365-1382.
    • (1995) Genetics , vol.141 , pp. 1365-1382
    • Raizen, D.M.1    Lee, R.Y.2    Avery, L.3
  • 60
    • 35648947912 scopus 로고    scopus 로고
    • Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans
    • Rea S.L., Ventura N., Johnson T.E. Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans. PLoS Biol. 2007, 5:e259.
    • (2007) PLoS Biol. , vol.5
    • Rea, S.L.1    Ventura, N.2    Johnson, T.E.3
  • 62
    • 0035126826 scopus 로고    scopus 로고
    • Historical perspective on the use of garlic
    • Rivlin R.S. Historical perspective on the use of garlic. J. Nutr. 2001, 131:951S-954S.
    • (2001) J. Nutr. , vol.131
    • Rivlin, R.S.1
  • 64
    • 33846931878 scopus 로고    scopus 로고
    • Cancer chemoprevention with garlic and its constituents
    • Shukla Y., Kalra N. Cancer chemoprevention with garlic and its constituents. Cancer Lett. 2007, 247:167-181.
    • (2007) Cancer Lett. , vol.247 , pp. 167-181
    • Shukla, Y.1    Kalra, N.2
  • 65
    • 0035122985 scopus 로고    scopus 로고
    • Study of garlic extracts and fractions on cholesterol plasma levels and vascular reactivity in cholesterol-fed rats
    • Slowing K., Ganado P., Sanz M., Ruiz E., Tejerina T. Study of garlic extracts and fractions on cholesterol plasma levels and vascular reactivity in cholesterol-fed rats. J. Nutr. 2001, 131:994S-999S.
    • (2001) J. Nutr. , vol.131
    • Slowing, K.1    Ganado, P.2    Sanz, M.3    Ruiz, E.4    Tejerina, T.5
  • 66
    • 39049143752 scopus 로고    scopus 로고
    • Metabolic effects of time-released garlic powder tablets in type 2 diabetes mellitus: the results of double-blinded placebo-controlled study
    • Sobenin I.A., Nedosugova L.V., Filatova L.V., Balabolkin M.I., Gorchakova T.V., Orekhov A.N. Metabolic effects of time-released garlic powder tablets in type 2 diabetes mellitus: the results of double-blinded placebo-controlled study. Acta Diabetol. 2008, 45:1-6.
    • (2008) Acta Diabetol. , vol.45 , pp. 1-6
    • Sobenin, I.A.1    Nedosugova, L.V.2    Filatova, L.V.3    Balabolkin, M.I.4    Gorchakova, T.V.5    Orekhov, A.N.6
  • 67
    • 33745714129 scopus 로고    scopus 로고
    • Determination of the concentration of diallyl trisulfide in rat whole blood using gas chromatography with electron-capture detection and identification of its major metabolite with gas chromatography mass spectrometry
    • Sun X., Guo T., He J., Zhao M., Yan M., Cui F., Deng Y. Determination of the concentration of diallyl trisulfide in rat whole blood using gas chromatography with electron-capture detection and identification of its major metabolite with gas chromatography mass spectrometry. Yakugaku Zasshi 2006, 126:521-527.
    • (2006) Yakugaku Zasshi , vol.126 , pp. 521-527
    • Sun, X.1    Guo, T.2    He, J.3    Zhao, M.4    Yan, M.5    Cui, F.6    Deng, Y.7
  • 68
    • 80055110125 scopus 로고    scopus 로고
    • Measuring Caenorhabditis elegans life span on solid media
    • pii: 1152, May
    • Sutphin G.L., Kaeberlein M. Measuring Caenorhabditis elegans life span on solid media. J. Vis. Exp. 2009, May 12;(27). pii: 1152.
    • (2009) J. Vis. Exp. , vol.12 , Issue.27
    • Sutphin, G.L.1    Kaeberlein, M.2
  • 71
    • 0032053198 scopus 로고    scopus 로고
    • Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display
    • Tawe W.N., Eschbach M.L., Walter R.D., Henkle-Duhrsen K. Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display. Nucleic Acids Res. 1998, 26:1621-1627.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1621-1627
    • Tawe, W.N.1    Eschbach, M.L.2    Walter, R.D.3    Henkle-Duhrsen, K.4
  • 72
    • 0035011923 scopus 로고    scopus 로고
    • In vitro activity of garlic oil and four diallyl sulphides against antibiotic-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae
    • Tsao S., Yin M. In vitro activity of garlic oil and four diallyl sulphides against antibiotic-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae. J. Antimicrob. Chemother. 2001, 47:665-670.
    • (2001) J. Antimicrob. Chemother. , vol.47 , pp. 665-670
    • Tsao, S.1    Yin, M.2
  • 73
    • 0034948918 scopus 로고    scopus 로고
    • In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils
    • Tsao S.M., Yin M.C. In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils. J. Med. Microbiol. 2001, 50:646-649.
    • (2001) J. Med. Microbiol. , vol.50 , pp. 646-649
    • Tsao, S.M.1    Yin, M.C.2
  • 74
    • 0346888678 scopus 로고    scopus 로고
    • Garlic extract and two diallyl sulphides inhibit methicillin-resistant Staphylococcus aureus infection in BALB/cA mice
    • Tsao S.M., Hsu C.C., Yin M.C. Garlic extract and two diallyl sulphides inhibit methicillin-resistant Staphylococcus aureus infection in BALB/cA mice. J. Antimicrob. Chemother. 2003, 52:974-980.
    • (2003) J. Antimicrob. Chemother. , vol.52 , pp. 974-980
    • Tsao, S.M.1    Hsu, C.C.2    Yin, M.C.3
  • 76
    • 26444442036 scopus 로고    scopus 로고
    • A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
    • Van Gilst M.R., Hadjivassiliou H., Yamamoto K.R. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc. Natl Acad. Sci. USA 2005, 102:13496-13501.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 13496-13501
    • Van Gilst, M.R.1    Hadjivassiliou, H.2    Yamamoto, K.R.3
  • 77
    • 27644585190 scopus 로고    scopus 로고
    • A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
    • Viswanathan M., Kim S.K., Berdichevsky A., Guarente L. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Dev. Cell 2005, 9:605-615.
    • (2005) Dev. Cell , vol.9 , pp. 605-615
    • Viswanathan, M.1    Kim, S.K.2    Berdichevsky, A.3    Guarente, L.4
  • 78
    • 33644836812 scopus 로고    scopus 로고
    • Homocysteine-lowering action is another potential cardiovascular protective factor of aged garlic extract
    • Yeh Y.Y., Yeh S.M. Homocysteine-lowering action is another potential cardiovascular protective factor of aged garlic extract. J. Nutr. 2006, 136:745S-749S.
    • (2006) J. Nutr. , vol.136
    • Yeh, Y.Y.1    Yeh, S.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.