Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme

Brain Research

Volumn 1343, Issue , 2010, Pages 178-185

  Ping, Zhang ^a   Liu, Wenwu ^b   Kang, Zhimin ^b   Cai, Jianmei ^b   Wang, Qiusha ^a   Cheng, Ni ^a   Wang, Sujian ^a   Wang, Shizhong ^a   Zhang, John H ^c   Sun, Xuejun ^b  

^a THE AFFILIATED CHANGZHOU NO 2 PEOPLE S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c LOMA LINDA UNIVERSITY   (United States)

Author keywords

Heme oxygenase 1; Hypoxic ischemia; NF E2 related factor 2; ROS; Sulforaphane

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CASPASE 3; HEME OXYGENASE 1; MALONALDEHYDE; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; TRIPHENYLTETRAZOLIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; BRAIN HYPOXIA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CAROTID ARTERY LIGATION; CELL ACTIVATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; LIPID PEROXIDATION; MACROGLIA; NERVE CELL; NEUROPROTECTION; NEWBORN; NICK END LABELING; NISSL STAINING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; ENZYME INDUCTION; HEME OXYGENASE (DECYCLIZING); HYPOXIA-ISCHEMIA, BRAIN; NAD(P)H DEHYDROGENASE (QUINONE); NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; RATS; RATS, SPRAGUE-DAWLEY; SECOND MESSENGER SYSTEMS; THIOCYANATES;

RATTUS;

EID: 77953620909     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.04.036     Document Type: Article

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