-
1
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
DOI 10.1038/sj.onc.1210414, PII 1210414
-
Meloche, S. and Pouyssegur, J. (2007) The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 26, 3227-3239 (Pubitemid 46763017)
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3227-3239
-
-
Meloche, S.1
Pouyssegur, J.2
-
2
-
-
30944447568
-
The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
-
DOI 10.1159/000094762, PII N130170763401
-
Yoon, S. and Seger, R. (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24, 21-44 (Pubitemid 43108774)
-
(2006)
Growth Factors
, vol.24
, Issue.1
, pp. 21-44
-
-
Yoon, S.1
Seger, R.2
-
3
-
-
24944490193
-
The ERK cascade: A prototype of MAPK signaling
-
DOI 10.1385/MB:31:2:151
-
Rubinfeld, H. and Seger, R. (2005) The ERK cascade: a prototype of MAPK signaling. Mol. Biotechnol. 31, 151-174 (Pubitemid 41306584)
-
(2005)
Molecular Biotechnology
, vol.31
, Issue.2
, pp. 151-174
-
-
Rubinfeld, H.1
Seger, R.2
-
4
-
-
84555216676
-
MAPK signaling in human diseases
-
Srivastava, R., ed., . Humana Press, Totowa
-
Roux, P. P. and Blenis, J. (2007) MAPK signaling in human diseases. In Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms (Srivastava, R., ed.), pp. 135-149, Humana Press, Totowa
-
(2007)
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms
, pp. 135-149
-
-
Roux, P.P.1
Blenis, J.2
-
6
-
-
33846201272
-
New insight into BRAF mutations in cancer
-
DOI 10.1016/j.gde.2006.12.005, PII S0959437X06002449, Genetic and Cellular mechanisms of oncogenesis
-
Dhomen, N. and Marais, R. (2007) New insight into BRAF mutations in cancer. Curr. Opin. Genet. Dev. 17, 31-39 (Pubitemid 46109299)
-
(2007)
Current Opinion in Genetics and Development
, vol.17
, Issue.1
, pp. 31-39
-
-
Dhomen, N.1
Marais, R.2
-
7
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
DOI 10.1128/MMBR.68.2.320-344.2004
-
Roux, P. P. and Blenis, J. (2004) ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68, 320-344 (Pubitemid 38756868)
-
(2004)
Microbiology and Molecular Biology Reviews
, vol.68
, Issue.2
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
8
-
-
79952435349
-
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
-
Cargnello, M. and Roux, P. P. (2011) Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol. Mol. Biol. Rev. 75, 50-83
-
(2011)
Microbiol. Mol. Biol. Rev.
, vol.75
, pp. 50-83
-
-
Cargnello, M.1
Roux, P.P.2
-
9
-
-
50049084144
-
MSK activation and physiological roles
-
Arthur, J. S. (2008) MSK activation and physiological roles. Front. Biosci. 13, 5866-5879
-
(2008)
Front. Biosci.
, vol.13
, pp. 5866-5879
-
-
Arthur, J.S.1
-
10
-
-
66949158732
-
The versatile role of MSKs in transcriptional regulation
-
Vermeulen, L., Berghe, W. V., Beck, I. M., De Bosscher, K. and Haegeman, G. (2009) The versatile role of MSKs in transcriptional regulation. Trends Biochem. Sci. 34, 311-318
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 311-318
-
-
Vermeulen, L.1
Berghe, W.V.2
Beck, I.M.3
De Bosscher, K.4
Haegeman, G.5
-
11
-
-
0016251762
-
The phosphorylation of liver ribosomal proteins in vivo. Evidence that only a single small subunit protein (S6) is phosphorylated
-
Gressner, A. M. and Wool, I. G. (1974) The phosphorylation of liver ribosomal proteins in vivo. Evidence that only a single small subunit protein (S6) is phosphorylated. J. Biol. Chem. 249, 6917-6925
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 6917-6925
-
-
Gressner, A.M.1
Wool, I.G.2
-
12
-
-
52049103675
-
Physiological roles of ribosomal protein S6: One of its kind
-
Meyuhas, O. (2008) Physiological roles of ribosomal protein S6: one of its kind. Int. Rev. Cell Mol. Biol. 268, 1-37
-
(2008)
Int. Rev. Cell Mol. Biol.
, vol.268
, pp. 1-37
-
-
Meyuhas, O.1
-
13
-
-
0021276961
-
Phosphorylation of the ribosomal protein S6 is elevated in cells transformed by a variety of tumor viruses
-
Blenis, J. and Erikson, R. L. (1984) Phosphorylation of the ribosomal protein S6 is elevated in cells transformed by a variety of tumor viruses. J. Virol. 50, 966-969 (Pubitemid 14105621)
-
(1984)
Journal of Virology
, vol.50
, Issue.3
, pp. 966-969
-
-
Blenis, J.1
Erikson, R.L.2
-
14
-
-
0019972979
-
Increased phosphorylation of ribosomal protein S6 during meiotic maturation of Xenopus oocytes
-
DOI 10.1073/pnas.79.9.2937
-
Nielsen, P. J., Thomas, G. and Maller, J. L. (1982) Increased phosphorylation of ribosomal protein S6 during meiotic maturation of Xenopus oocytes. Proc. Natl. Acad. Sci. U.S.A. 79, 2937-2941 (Pubitemid 12032346)
-
(1982)
Proceedings of the National Academy of Sciences of the United States of America
, vol.79
, Issue.9 I
, pp. 2937-2941
-
-
Nielsen, P.J.1
Thomas, G.2
Maller, J.L.3
-
16
-
-
0344737208
-
A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases
-
Jones, S. W., Erikson, E., Blenis, J., Maller, J. L. and Erikson, R. L. (1988) A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases. Proc. Natl. Acad. Sci. U.S.A. 85, 3377-3381
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 3377-3381
-
-
Jones, S.W.1
Erikson, E.2
Blenis, J.3
Maller, J.L.4
Erikson, R.L.5
-
17
-
-
0023766145
-
Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
-
Sturgill, T. W., Ray, L. B., Erikson, E. and Maller, J. L. (1988) Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 334, 715-718
-
(1988)
Nature
, vol.334
, pp. 715-718
-
-
Sturgill, T.W.1
Ray, L.B.2
Erikson, E.3
Maller, J.L.4
-
18
-
-
0022649274
-
Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6
-
Erikson, E. and Maller, J. L. (1986) Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6. J. Biol. Chem. 261, 350-355 (Pubitemid 16103952)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.1
, pp. 350-355
-
-
Erikson, E.1
Maller, J.L.2
-
20
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
-
Chung, J., Kuo, C. J., Crabtree, G. R. and Blenis, J. (1992) Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 69, 1227-1236
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
21
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase
-
Kuo, C. J., Chung, J., Fiorentino, D. F., Flanagan, W. M., Blenis, J. and Crabtree, G. R. (1992) Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature 358, 70-73
-
(1992)
Nature
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Fiorentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
22
-
-
11144356304
-
-/- mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
-
-/- mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol. Cell. Biol. 24, 3112-3124
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3112-3124
-
-
Pende, M.1
Um, S.H.2
Mieulet, V.3
Sticker, M.4
Goss, V.L.5
Mestan, J.6
Mueller, M.7
Fumagalli, S.8
Kozma, S.C.9
Thomas, G.10
-
23
-
-
34347242470
-
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
-
DOI 10.1074/jbc.M700906200
-
Roux, P. P., Shahbazian, D., Vu, H., Holz, M. K., Cohen, M. S., Taunton, J., Sonenberg, N. and Blenis, J. (2007) RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J. Biol. Chem. 282, 14056-14064 (Pubitemid 47100467)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.19
, pp. 14056-14064
-
-
Roux, P.P.1
Shahbazian, D.2
Vu, H.3
Holz, M.K.4
Cohen, M.S.5
Taunton, J.6
Sonenberg, N.7
Blenis, J.8
-
27
-
-
0030063435
-
Evidence for two catalytically active kinase domains in pp90rsk
-
Fisher, T. L. and Blenis, J. (1996) Evidence for two catalytically active kinase domains in pp90rsk. Mol. Cell. Biol. 16, 1212-1219
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1212-1219
-
-
Fisher, T.L.1
Blenis, J.2
-
28
-
-
52049088725
-
The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases)
-
Buxade, M., Parra-Palau, J. L. and Proud, C. G. (2008) The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases). Front. Biosci. 13, 5359-5373
-
(2008)
Front. Biosci.
, vol.13
, pp. 5359-5373
-
-
Buxade, M.1
Parra-Palau, J.L.2
Proud, C.G.3
-
29
-
-
52049118753
-
MK2 and MK3 - A pair of isoenzymes?
-
Ronkina, N., Kotlyarov, A. and Gaestel, M. (2008) MK2 and MK3 - a pair of isoenzymes? Front. Biosci. 13, 5511-5521
-
(2008)
Front. Biosci.
, vol.13
, pp. 5511-5521
-
-
Ronkina, N.1
Kotlyarov, A.2
Gaestel, M.3
-
30
-
-
42549091024
-
Does MK5 reconcile classical and atypical MAP kinases?
-
DOI 10.2741/3027
-
Perander, M., Keyse, S. M. and Seternes, O. M. (2008) Does MK5 reconcile classical and atypical MAP kinases? Front. Biosci. 13, 4617-4624 (Pubitemid 351589186)
-
(2008)
Frontiers in Bioscience
, vol.13
, Issue.12
, pp. 4617-4624
-
-
Perander, M.1
Keyse, S.M.2
Seternes, O.-M.3
-
32
-
-
0031577164
-
Identification of serine 380 as the major site of autophosphorylation of Xenopus pp90rsk
-
DOI 10.1006/bbrc.1997.6794
-
Vik, T. A. and Ryder, J. W. (1997) Identification of serine 380 as the major site of autophosphorylation of Xenopus pp90rsk. Biochem. Biophys. Res. Commun. 235, 398-402 (Pubitemid 27313719)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.235
, Issue.2
, pp. 398-402
-
-
Vik, T.A.1
Ryder, J.W.2
-
33
-
-
0037008784
-
Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase
-
DOI 10.1074/jbc.M202663200
-
Chrestensen, C. A. and Sturgill, T. W. (2002) Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase. J. Biol. Chem. 277, 27733-27741 (Pubitemid 34966717)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.31
, pp. 27733-27741
-
-
Chrestensen, C.A.1
Sturgill, T.W.2
-
34
-
-
0037400611
-
Molecular recognitions in the MAP kinase cascades
-
DOI 10.1016/S0898-6568(02)00112-2
-
Tanoue, T. and Nishida, E. (2003) Molecular recognitions in the MAP kinase cascades. Cell. Signal. 15, 455-462 (Pubitemid 36287667)
-
(2003)
Cellular Signalling
, vol.15
, Issue.5
, pp. 455-462
-
-
Tanoue, T.1
Nishida, E.2
-
35
-
-
0034595707
-
2-terminal UCR regions
-
DOI 10.1074/jbc.275.22.16609
-
MacKenzie, S. J., Baillie, G. S., McPhee, I., Bolger, G. B. and Houslay, M. D. (2000) ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions. J. Biol. Chem. 275, 16609-16617 (Pubitemid 30398887)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.22
, pp. 16609-16617
-
-
MacKenzie, S.J.1
Baillie, G.S.2
McPhee, I.3
Bolger, G.B.4
Houslay, M.D.5
-
36
-
-
0032534791
-
PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif
-
DOI 10.1093/emboj/17.24.7337
-
Pulido, R., Zuniga, A. and Ullrich, A. (1998) PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif. EMBO J. 17, 7337-7350 (Pubitemid 29002702)
-
(1998)
EMBO Journal
, vol.17
, Issue.24
, pp. 7337-7350
-
-
Pulido, R.1
Zuniga, A.2
Ullrich, A.3
-
37
-
-
0033613857
-
Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo
-
DOI 10.1074/jbc.274.5.2893
-
Smith, J. A., Poteet-Smith, C. E., Malarkey, K. and Sturgill, T. W. (1999) Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo. J. Biol. Chem. 274, 2893-2898 (Pubitemid 29075375)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.5
, pp. 2893-2898
-
-
Smith, J.A.1
Poteet-Smith, C.E.2
Malarkey, K.3
Sturgill, T.W.4
-
39
-
-
0038112035
-
Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity
-
DOI 10.1128/MCB.23.14.4796-4804.2003
-
Roux, P. P., Richards, S. A. and Blenis, J. (2003) Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity. Mol. Cell. Biol. 23, 4796-4804 (Pubitemid 36793327)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.14
, pp. 4796-4804
-
-
Roux, P.P.1
Richards, S.A.2
Blenis, J.3
-
40
-
-
27244433306
-
Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission
-
DOI 10.1073/pnas.0507476102
-
Thomas, G. M., Rumbaugh, G. R., Harrar, D. B. and Huganir, R. L. (2005) Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission. Proc. Natl. Acad. Sci. U.S.A. 102, 15006-15011 (Pubitemid 41513325)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.42
, pp. 15006-15011
-
-
Thomas, G.M.1
Rumbaugh, G.R.2
Harrar, D.B.3
Huganir, R.L.4
-
41
-
-
0036848266
-
Expression analysis of RSK gene family members: The RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning
-
Zeniou, M., Ding, T., Trivier, E. and Hanauer, A. (2002) Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum. Mol. Genet. 11, 2929-2940
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2929-2940
-
-
Zeniou, M.1
Ding, T.2
Trivier, E.3
Hanauer, A.4
-
42
-
-
76249090489
-
BioGPS: An extensible and customizable portal for querying and organizing gene annotation resources
-
Wu, C., Orozco, C., Boyer, J., Leglise, M., Goodale, J., Batalov, S., Hodge, C. L., Haase, J., Janes, J., Huss, III, J. W. and Su, A. I. (2009) BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol. 10, R130
-
(2009)
Genome Biol.
, vol.10
-
-
Wu, C.1
Orozco, C.2
Boyer, J.3
Leglise, M.4
Goodale, J.5
Batalov, S.6
Hodge, C.L.7
Haase, J.8
Janes, J.9
Huss III, J.W.10
Su, A.I.11
-
43
-
-
0024439162
-
Sequence and expression of chicken and mouse rsk: Homologs of Xenopus laevis ribosomal S6 kinase
-
Alcorta, D. A., Crews, C. M., Sweet, L. J., Bankston, L., Jones, S. W. and Erikson, R. L. (1989) Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase. Mol. Cell. Biol. 9, 3850-3859 (Pubitemid 19216278)
-
(1989)
Molecular and Cellular Biology
, vol.9
, Issue.9
, pp. 3850-3859
-
-
Alcorta, D.A.1
Crews, C.M.2
Sweet, L.J.3
Bankston, L.4
Jones, S.W.5
Erikson, R.L.6
-
44
-
-
0028217280
-
Human rsk isoforms: Cloning and characterization of tissue-specific expression
-
Moller, D. E., Xia, C. H., Tang, W., Zhu, A. X. and Jakubowski, M. (1994) Human rsk isoforms: cloning and characterization of tissue-specific expression. Am. J. Physiol. 266, 351-359
-
(1994)
Am. J. Physiol.
, vol.266
, pp. 351-359
-
-
Moller, D.E.1
Xia, C.H.2
Tang, W.3
Zhu, A.X.4
Jakubowski, M.5
-
45
-
-
18944403738
-
Differential localization of MAPK-activated protein kinases RSK1 and MSK1 in mouse brain
-
DOI 10.1016/j.molbrainres.2005.01.014, PII S0169328X05000380
-
Heffron, D. and Mandell, J. W. (2005) Differential localization of MAPK-activated protein kinases RSK1 and MSK1 in mouse brain. Brain Res. Mol. Brain Res. 136, 134-141 (Pubitemid 40704616)
-
(2005)
Molecular Brain Research
, vol.136
, Issue.1-2
, pp. 134-141
-
-
Heffron, D.1
Mandell, J.W.2
-
46
-
-
17144370207
-
Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types
-
DOI 10.1074/jbc.M408194200
-
Dummler, B. A., Hauge, C., Silber, J., Yntema, H. G., Kruse, L. S., Kofoed, B., Hemmings, B. A., Alessi, D. R. and Frodin, M. (2005) Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types. J. Biol. Chem. 280, 13304-13314 (Pubitemid 40517216)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.14
, pp. 13304-13314
-
-
Dummler, B.A.1
Hauge, C.2
Silber, J.3
Yntema, H.G.4
Kruse, L.S.5
Kofoed, B.6
Hemmings, B.A.7
Alessi, D.R.8
Frodin, M.9
-
47
-
-
0037407415
-
Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis
-
DOI 10.1016/S1567-133X(03)00004-8, PII S1567133X03000048
-
Kohn, M., Hameister, H., Vogel, M. and Kehrer-Sawatzki, H. (2003) Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis. Gene Expr. Patterns 3, 173-177 (Pubitemid 36511306)
-
(2003)
Gene Expression Patterns
, vol.3
, Issue.2
, pp. 173-177
-
-
Kohn, M.1
Hameister, H.2
Vogel, M.3
Kehrer-Sawatzki, H.4
-
48
-
-
0033572435
-
A novel ribosomal S6-kinase (RSK4; RPS6KA6) is commonly deleted in patients with complex X-linked mental retardation
-
DOI 10.1006/geno.1999.6004
-
Yntema, H. G., van den Helm, B., Kissing, J., van Duijnhoven, G., Poppelaars, F., Chelly, J., Moraine, C., Fryns, J. P., Hamel, B. C., Heilbronner, H. et al. (1999) A novel ribosomal S6-kinase (RSK4; RPS6KA6) is commonly deleted in patients with complex X-linked mental retardation. Genomics 62, 332-343 (Pubitemid 30075162)
-
(1999)
Genomics
, vol.62
, Issue.3
, pp. 332-343
-
-
Yntema, H.G.1
Van Den, H.B.2
Kissing, J.3
Van Duijnhoven, G.4
Poppelaars, F.5
Chelly, J.6
Moraine, C.7
Fryns, J.-P.8
Hamel, B.C.J.9
Heilbronner, H.10
Pander, H.-J.11
Brunner, H.G.12
Ropers, H.-H.13
Cremers, F.P.M.14
Van Bokhoven, H.15
-
49
-
-
0026608787
-
Nuclear localization and regulation of erk - And rsk -encoded protein kinases
-
Chen, R. H., Sarnecki, C. and Blenis, J. (1992) Nuclear localization and regulation of erk - and rsk -encoded protein kinases. Mol. Cell. Biol. 12, 915-927
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 915-927
-
-
Chen, R.H.1
Sarnecki, C.2
Blenis, J.3
-
52
-
-
0034785929
-
Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1
-
DOI 10.1128/MCB.21.21.7470-7480.2001
-
Richards, S. A., Dreisbach, V. C., Murphy, L. O. and Blenis, J. (2001) Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1. Mol. Cell. Biol. 21, 7470-7480 (Pubitemid 32953497)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.21
, pp. 7470-7480
-
-
Richards, S.A.1
Dreisbach, V.C.2
Murphy, L.O.3
Blenis, J.4
-
53
-
-
0042858127
-
RSK2 activity is regulated by its interaction with PEA-15
-
DOI 10.1074/jbc.M303988200
-
Vaidyanathan, H. and Ramos, J. W. (2003) RSK2 activity is regulated by its interaction with PEA-15. J. Biol. Chem. 278, 32367-32372 (Pubitemid 37048433)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.34
, pp. 32367-32372
-
-
Vaidyanathan, H.1
Ramos, J.W.2
-
54
-
-
52649130815
-
Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival
-
Eisinger-Mathason, T. S., Andrade, J., Groehler, A. L., Clark, D. E., Muratore-Schroeder, T. L., Pasic, L., Smith, J. A., Shabanowitz, J., Hunt, D. F., Macara, I. G. and Lannigan, D. A. (2008) Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Mol. Cell 31, 722-736
-
(2008)
Mol. Cell
, vol.31
, pp. 722-736
-
-
Eisinger-Mathason, T.S.1
Andrade, J.2
Groehler, A.L.3
Clark, D.E.4
Muratore-Schroeder, T.L.5
Pasic, L.6
Smith, J.A.7
Shabanowitz, J.8
Hunt, D.F.9
Macara, I.G.10
Lannigan, D.A.11
-
55
-
-
0031952597
-
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90(rsk) that are inducible by MAPK
-
DOI 10.1074/jbc.273.3.1496
-
Dalby, K. N., Morrice, N., Caudwell, F. B., Avruch, J. and Cohen, P. (1998) Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)- activated protein kinase-1a/p90rsk that are inducible by MAPK. J. Biol. Chem. 273, 1496-1505 (Pubitemid 28133672)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.3
, pp. 1496-1505
-
-
Dalby, K.N.1
Morrice, N.2
Caudwell, F.B.3
Avruch, J.4
Cohen, P.5
-
56
-
-
0033578776
-
90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1
-
Jensen, C. J., Buch, M. B., Krag, T. O., Hemmings, B. A., Gammeltoft, S. and Frodin, M. (1999) 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. J Biol. Chem. 274, 27168-27176
-
(1999)
J Biol. Chem.
, vol.274
, pp. 27168-27176
-
-
Jensen, C.J.1
Buch, M.B.2
Krag, T.O.3
Hemmings, B.A.4
Gammeltoft, S.5
Frodin, M.6
-
57
-
-
0033615078
-
Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK
-
DOI 10.1016/S0960-9822(99)80364-9
-
Richards, S. A., Fu, J., Romanelli, A., Shimamura, A. and Blenis, J. (1999) Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK. Curr. Biol. 9, 810-820 (Pubitemid 29375183)
-
(1999)
Current Biology
, vol.9
, Issue.15
, pp. 810-820
-
-
Richards, S.A.1
Fu, J.2
Romanelli, A.3
Shimamura, A.4
Blenis, J.5
-
58
-
-
1342342993
-
PDK1, the master regulator of AGC kinase signal transduction
-
DOI 10.1016/j.semcdb.2003.12.022
-
Mora, A., Komander, D., van Aalten, D. M. and Alessi, D. R. (2004) PDK1, the master regulator of AGC kinase signal transduction. Semin. Cell Dev. Biol. 15, 161-170 (Pubitemid 38251644)
-
(2004)
Seminars in Cell and Developmental Biology
, vol.15
, Issue.2
, pp. 161-170
-
-
Mora, A.1
Komander, D.2
Van Aalten, D.M.F.3
Alessi, D.R.4
-
59
-
-
0034176579
-
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
-
DOI 10.1016/S0960-9822(00)00441-3
-
Williams, M. R., Arthur, J. S., Balendran, A., van der Kaay, J., Poli, V., Cohen, P. and Alessi, D. R. (2000) The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells. Curr. Biol. 10, 439-448 (Pubitemid 30247331)
-
(2000)
Current Biology
, vol.10
, Issue.8
, pp. 439-448
-
-
Williams, M.R.1
Arthur, J.S.C.2
Balendran, A.3
Van Der, K.J.4
Poli, V.5
Cohen, P.6
Alessi, D.R.7
-
60
-
-
2942563750
-
3 binding to PDK1 PH domain defined by knockin mutation
-
3 binding to PDK1 PH domain defined by knockin mutation. EMBO J. 23, 2071-2082
-
(2004)
EMBO J.
, vol.23
, pp. 2071-2082
-
-
McManus, E.J.1
Collins, B.J.2
Ashby, P.R.3
Prescott, A.R.4
Murray-Tait, V.5
Armit, L.J.6
Arthur, J.S.7
Alessi, D.R.8
-
61
-
-
0037337159
-
Regulation of the ABC kinases by phosphorylation: Protein kinase C as a paradigm
-
Newton, A. C. (2003) Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem. J. 370, 361-371
-
(2003)
Biochem. J.
, vol.370
, pp. 361-371
-
-
Newton, A.C.1
-
62
-
-
0242612949
-
A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1
-
Frodin, M., Jensen, C. J., Merienne, K. and Gammeltoft, S. (2000) A phosphoserineregulated docking site in the protein kinase RSK2 that recruits and activates PDK1. EMBO J. 19, 2924-2934 (Pubitemid 30386764)
-
(2000)
EMBO Journal
, vol.19
, Issue.12
, pp. 2924-2934
-
-
Frodin, M.1
Jensen, C.J.2
Merienne, K.3
Gammeltoft, S.4
-
63
-
-
0037107414
-
A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation
-
DOI 10.1093/emboj/cdf551
-
Frodin, M., Antal, T. L., Dummler, B. A., Jensen, C. J., Deak, M., Gammeltoft, S. and Biondi, R. M. (2002) A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation. EMBO J. 21, 5396-5407 (Pubitemid 35231019)
-
(2002)
EMBO Journal
, vol.21
, Issue.20
, pp. 5396-5407
-
-
Frodin, M.1
Antal, T.L.2
Dummler, B.A.3
Jensen, C.J.4
Deak, M.5
Gammeltoft, S.6
Biondi, R.M.7
-
64
-
-
0027508290
-
Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2
-
DOI 10.1111/j.1432-1033.1993.tb18297.x
-
Sutherland, C., Alterio, J., Campbell, D. G., Le Bourdelles, B., Mallet, J., Haavik, J. and Cohen, P. (1993) Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2. Eur. J. Biochem. 217, 715-722 (Pubitemid 23311985)
-
(1993)
European Journal of Biochemistry
, vol.217
, Issue.2
, pp. 715-722
-
-
Sutherland, C.1
Alterio, J.2
Campbell, D.G.3
Le, B.B.4
Mallet, J.5
Haavik, J.6
Cohen, P.7
-
65
-
-
0027400484
-
Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rsk(mo)-2. Identification of two threonines phosphorylated during activation by mitogen-activated protein kinase
-
Sutherland, C., Campbell, D. G. and Cohen, P. (1993) Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2: identification of two threonines phosphorylated during activation by mitogen-activated protein kinase. Eur. J. Biochem. 212, 581-588 (Pubitemid 23076128)
-
(1993)
European Journal of Biochemistry
, vol.212
, Issue.2
, pp. 581-588
-
-
Sutherland, C.1
Campbell, D.G.2
Cohen, P.3
-
66
-
-
33646148718
-
The MAP kinase ERK5 binds to and phosphorylates p90 RSK
-
Ranganathan, A., Pearson, G. W., Chrestensen, C. A., Sturgill, T. W. and Cobb, M. H. (2006) The MAP kinase ERK5 binds to and phosphorylates p90 RSK. Arch. Biochem. Biophys. 449, 8-16
-
(2006)
Arch. Biochem. Biophys.
, vol.449
, pp. 8-16
-
-
Ranganathan, A.1
Pearson, G.W.2
Chrestensen, C.A.3
Sturgill, T.W.4
Cobb, M.H.5
-
67
-
-
34548253333
-
FGFR3 Activates RSK2 to Mediate Hematopoietic Transformation through Tyrosine Phosphorylation of RSK2 and Activation of the MEK/ERK Pathway
-
DOI 10.1016/j.ccr.2007.08.003, PII S1535610807002322
-
Kang, S., Dong, S., Gu, T. L., Guo, A., Cohen, M. S., Lonial, S., Khoury, H. J., Fabbro, D., Gilliland, D. G., Bergsagel, P. L. et al. (2007) FGFR3 Activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Cancer Cell 12, 201-214 (Pubitemid 47333416)
-
(2007)
Cancer Cell
, vol.12
, Issue.3
, pp. 201-214
-
-
Kang, S.1
Dong, S.2
Gu, T.-L.3
Guo, A.4
Cohen, M.S.5
Lonial, S.6
Khoury, H.J.7
Fabbro, D.8
Gilliland, D.G.9
Bergsagel, P.L.10
Taunton, J.11
Polakiewicz, R.D.12
Chen, J.13
-
68
-
-
41949086525
-
Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529
-
Kang, S., Dong, S., Guo, A., Ruan, H., Lonial, S., Khoury, H. J., Gu, T. L. and Chen, J. (2008) Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529. J. Biol. Chem. 283, 4652-4657
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4652-4657
-
-
Kang, S.1
Dong, S.2
Guo, A.3
Ruan, H.4
Lonial, S.5
Khoury, H.J.6
Gu, T.L.7
Chen, J.8
-
69
-
-
33847042741
-
A clickable inhibitor reveals context-dependent autoactivation of p90 RSK
-
Cohen, M. S., Hadjivassiliou, H. and Taunton, J. (2007) A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. Nat. Chem. Biol. 3, 156-160
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 156-160
-
-
Cohen, M.S.1
Hadjivassiliou, H.2
Taunton, J.3
-
70
-
-
35548930283
-
The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways
-
DOI 10.1038/ni1517, PII NI1517
-
Zaru, R., Ronkina, N., Gaestel, M., Arthur, J. S. and Watts, C. (2007) The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways. Nat. Immunol. 8, 1227-1235 (Pubitemid 350011762)
-
(2007)
Nature Immunology
, vol.8
, Issue.11
, pp. 1227-1235
-
-
Zaru, R.1
Ronkina, N.2
Gaestel, M.3
Arthur, J.S.C.4
Watts, C.5
-
71
-
-
33745041709
-
Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase
-
DOI 10.1128/MCB.01422-05
-
Chaturvedi, D., Poppleton, H. M., Stringfield, T., Barbier, A. and Patel, T. B. (2006) Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase. Mol. Cell. Biol. 26, 4586-4600 (Pubitemid 43877577)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.12
, pp. 4586-4600
-
-
Chaturvedi, D.1
Poppleton, H.M.2
Stringfield, T.3
Barbier, A.4
Patel, T.B.5
-
72
-
-
69949174646
-
The PKARIá subunit of protein kinase A modulates the activation of p90RSK1 and its function
-
Chaturvedi, D., Cohen, M. S., Taunton, J. and Patel, T. B. (2009) The PKARIá subunit of protein kinase A modulates the activation of p90RSK1 and its function. J. Biol. Chem. 284, 23670-23681
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 23670-23681
-
-
Chaturvedi, D.1
Cohen, M.S.2
Taunton, J.3
Patel, T.B.4
-
73
-
-
4544241565
-
p90 ribosomal S6 kinase 2 is associated with and dephosphorylated by protein phosphatase 2Cδ
-
DOI 10.1042/BJ20040948
-
Doehn, U., Gammeltoft, S., Shen, S. H. and Jensen, C. J. (2004) p90 ribosomal S6 kinase 2 is associated with and dephosphorylated by protein phosphatase 2Cδ. Biochem. J. 382, 425-431 (Pubitemid 39243908)
-
(2004)
Biochemical Journal
, vol.382
, Issue.2
, pp. 425-431
-
-
Doehn, U.1
Gammeltoft, S.2
Shen, S.-H.3
Jensen, C.J.4
-
74
-
-
55249097500
-
Targeting RSK: An overview of small molecule inhibitors
-
Nguyen, T. L. (2008) Targeting RSK: an overview of small molecule inhibitors. Anticancer Agents Med. Chem. 8, 710-716
-
(2008)
Anticancer Agents Med. Chem.
, vol.8
, pp. 710-716
-
-
Nguyen, T.L.1
-
75
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., McLauchlan, H., Klevernic, I., Arthur, J. S., Alessi, D. R. and Cohen, P. (2007) The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408, 297-315
-
(2007)
Biochem. J.
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
76
-
-
33846312875
-
BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo
-
DOI 10.1042/BJ20061088
-
Sapkota, G. P., Cummings, L., Newell, F. S., Armstrong, C., Bain, J., Frodin, M., Grauert, M., Hoffmann, M., Schnapp, G., Steegmaier, M. et al. (2007) BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem. J. 401, 29-38 (Pubitemid 46114597)
-
(2007)
Biochemical Journal
, vol.401
, Issue.1
, pp. 29-38
-
-
Sapkota, G.P.1
Cummings, L.2
Newell, F.S.3
Armstrong, C.4
Bain, J.5
Frodin, M.6
Grauert, M.7
Hoffmann, M.8
Schnapp, G.9
Steegmaier, M.10
Cohen, P.11
Alessi, D.R.12
-
77
-
-
13444270324
-
Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation
-
Smith, J. A., Poteet-Smith, C. E., Xu, Y., Errington, T. M., Hecht, S. M. and Lannigan, D. A. (2005) Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. Cancer Res. 65, 1027-1034 (Pubitemid 40216465)
-
(2005)
Cancer Research
, vol.65
, Issue.3
, pp. 1027-1034
-
-
Smith, J.A.1
Poteet-Smith, C.E.2
Xu, Y.3
Errington, T.M.4
Hecht, S.M.5
Lannigan, D.A.6
-
78
-
-
19744364796
-
Biochemistry: Structural bioinformatics-based design of selective, irreversible kinase inhibitors
-
DOI 10.1126/science1108367
-
Cohen, M. S., Zhang, C., Shokat, K. M. and Taunton, J. (2005) Structural bioinformatics-based design of selective, irreversible kinase inhibitors. Science 308, 1318-1321 (Pubitemid 40746129)
-
(2005)
Science
, vol.308
, Issue.5726
, pp. 1318-1321
-
-
Cohen, M.S.1
Zhang, C.2
Shokat, K.M.3
Taunton, J.4
-
79
-
-
0028875925
-
Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: The N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation
-
Leighton, I. A., Dalby, K. N., Caudwell, F. B., Cohen, P. T. and Cohen, P. (1995) Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation. FEBS Lett. 375, 289-293
-
(1995)
FEBS Lett.
, vol.375
, pp. 289-293
-
-
Leighton, I.A.1
Dalby, K.N.2
Caudwell, F.B.3
Cohen, P.T.4
Cohen, P.5
-
80
-
-
68949210380
-
RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells
-
Doehn, U., Hauge, C., Frank, S. R., Jensen, C. J., Duda, K., Nielsen, J. V., Cohen, M. S., Johansen, J. V., Winther, B. R., Lund, L. R. et al. (2009) RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol. Cell 35, 511-522
-
(2009)
Mol. Cell
, vol.35
, pp. 511-522
-
-
Doehn, U.1
Hauge, C.2
Frank, S.R.3
Jensen, C.J.4
Duda, K.5
Nielsen, J.V.6
Cohen, M.S.7
Johansen, J.V.8
Winther, B.R.9
Lund, L.R.10
-
81
-
-
12944293128
-
Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c-Fos gene
-
DOI 10.1073/pnas.97.6.2462
-
Bruning, J. C., Gillette, J. A., Zhao, Y., Bjorbaeck, C., Kotzka, J., Knebel, B., Avci, H., Hanstein, B., Lingohr, P., Moller, D. E. et al. (2000) Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c-Fos gene. Proc. Natl. Acad. Sci. U.S.A. 97, 2462-2467 (Pubitemid 30159193)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.6
, pp. 2462-2467
-
-
Bruning, J.C.1
Gillette, J.A.2
Zhao, Y.3
Bjorbaeck, C.4
Kotzka, J.5
Knebel, B.6
Avci, H.7
Hanstein, B.8
Lingohr, P.9
Moller, D.E.10
Krone, W.11
Kahn, C.R.12
Muller-Wieland, D.13
-
82
-
-
0032514734
-
Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene
-
DOI 10.1073/pnas.95.21.12202
-
De Cesare, D., Jacquot, S., Hanauer, A. and Sassone-Corsi, P. (1998) Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. Proc. Natl. Acad. Sci. U.S.A. 95, 12202-12207 (Pubitemid 28483743)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.21
, pp. 12202-12207
-
-
De Cesare, D.1
Jacquot, S.2
Hanauer, A.3
Sassone-Corsi, P.4
-
83
-
-
0028338460
-
Nerve growth factor activates a ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB
-
DOI 10.1016/0092-8674(94)90055-8
-
Ginty, D. D., Bonni, A. and Greenberg, M. E. (1994) Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 77, 713-725 (Pubitemid 24175607)
-
(1994)
Cell
, vol.77
, Issue.5
, pp. 713-725
-
-
Ginty, D.D.1
Bonni, A.2
Greenberg, M.E.3
-
84
-
-
0029789643
-
Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
-
Xing, J., Ginty, D. D. and Greenberg, M. E. (1996) Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 273, 959-963 (Pubitemid 26275173)
-
(1996)
Science
, vol.273
, Issue.5277
, pp. 959-963
-
-
Xing, J.1
Ginty, D.D.2
Greenberg, M.E.3
-
85
-
-
0036193378
-
MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts
-
DOI 10.1128/MCB.22.8.2871-2881.2002
-
Wiggin, G. R., Soloaga, A., Foster, J. M., Murray-Tait, V., Cohen, P. and Arthur, J. S. (2002) MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts. Mol. Cell. Biol. 22, 2871-2881 (Pubitemid 34263007)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.8
, pp. 2871-2881
-
-
Wiggin, G.R.1
Soloaga, A.2
Foster, J.M.3
Murray-Tait, V.4
Cohen, P.5
Arthur, J.S.C.6
-
86
-
-
0038182524
-
MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14
-
DOI 10.1093/emboj/cdg273
-
Soloaga, A., Thomson, S., Wiggin, G. R., Rampersaud, N., Dyson, M. H., Hazzalin, C. A., Mahadevan, L. C. and Arthur, J. S. (2003) MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. EMBO J. 22, 2788-2797 (Pubitemid 36712374)
-
(2003)
EMBO Journal
, vol.22
, Issue.11
, pp. 2788-2797
-
-
Soloaga, A.1
Thomson, S.2
Wiggin, G.R.3
Rampersaud, N.4
Dyson, M.H.5
Hazzalin, C.A.6
Mahadevan, L.C.7
Arthur, J.S.C.8
-
87
-
-
0027385031
-
A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity
-
Rivera, V. M., Miranti, C. K., Misra, R. P., Ginty, D. D., Chen, R. H., Blenis, J. and Greenberg, M. E. (1993) A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Mol. Cell. Biol. 13, 6260-6273 (Pubitemid 23292620)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.10
, pp. 6260-6273
-
-
Rivera, V.M.1
Miranti, C.K.2
Misra, R.P.3
Ginty, D.D.4
Chen, R.-H.5
Blenis, J.6
Greenberg, M.E.7
-
88
-
-
0027361017
-
Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase
-
DOI 10.1073/pnas.90.23.10952
-
Chen, R. H., Abate, C. and Blenis, J. (1993) Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase. Proc. Natl. Acad. Sci. U.S.A. 90, 10952-10956 (Pubitemid 23354346)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 10952-10956
-
-
Chen, R.-H.1
Abate, C.2
Blenis, J.3
-
89
-
-
0027223906
-
Functional domains and phosphorylation of the orphan receptor Nur77
-
DOI 10.1210/me.7.8.953
-
Davis, I. J., Hazel, T. G., Chen, R. H., Blenis, J. and Lau, L. F. (1993) Functional domains and phosphorylation of the orphan receptor Nur77. Mol. Endocrinol. 7, 953-964 (Pubitemid 23252334)
-
(1993)
Molecular Endocrinology
, vol.7
, Issue.8
, pp. 953-964
-
-
Davis, I.J.1
Hazel, T.G.2
Chen, R.-H.3
Blenis, J.4
Lau, L.F.5
-
90
-
-
31544443527
-
Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation
-
DOI 10.1042/BJ20050967
-
Wingate, A. D., Campbell, D. G., Peggie, M. and Arthur, J. S. (2006) Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation. Biochem. J. 393, 715-724 (Pubitemid 43163811)
-
(2006)
Biochemical Journal
, vol.393
, Issue.3
, pp. 715-724
-
-
Wingate, A.D.1
Campbell, D.G.2
Peggie, M.3
Arthur, J.S.C.4
-
91
-
-
20044390185
-
Essential role of RSK2 in c-Fos-dependent osteosarcoma development
-
DOI 10.1172/JCI200522877
-
David, J. P., Mehic, D., Bakiri, L., Schilling, A. F., Mandic, V., Priemel, M., Idarraga, M. H., Reschke, M. O., Hoffmann, O., Amling, M. and Wagner, E. F. (2005) Essential role of RSK2 in c-Fos-dependent osteosarcoma development. J. Clin. Invest. 115, 664-672 (Pubitemid 40322240)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.3
, pp. 664-672
-
-
David, J.-P.1
Mehic, D.2
Bakiri, L.3
Schilling, A.F.4
Mandic, V.5
Priemel, M.6
Idarraga, M.H.7
Reschke, M.O.8
Hoffmann, O.9
Amling, M.10
Wagner, E.F.11
-
92
-
-
79953230058
-
Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis
-
Bakiri, L., Reschke, M. O., Gefroh, H. A., Idarraga, M. H., Polzer, K., Zenz, R., Schett, G. and Wagner, E. F. (2011) Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis. Oncogene 30, 1506-1517
-
(2011)
Oncogene
, vol.30
, pp. 1506-1517
-
-
Bakiri, L.1
Reschke, M.O.2
Gefroh, H.A.3
Idarraga, M.H.4
Polzer, K.5
Zenz, R.6
Schett, G.7
Wagner, E.F.8
-
93
-
-
0037291736
-
ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth
-
DOI 10.1016/S1097-2765(03)00036-4
-
Zhao, J., Yuan, X., Frodin, M. and Grummt, I. (2003) ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. Mol. Cell 11, 405-413 (Pubitemid 36293834)
-
(2003)
Molecular Cell
, vol.11
, Issue.2
, pp. 405-413
-
-
Zhao, J.1
Yuan, X.2
Frodin, M.3
Grummt, I.4
-
95
-
-
71549166007
-
MTOR/S6K1 and MAPK/RSK signaling pathways coordinately regulate estrogen receptor á serine 167 phosphorylation
-
Yamnik, R. L. and Holz, M. K. (2010) mTOR/S6K1 and MAPK/RSK signaling pathways coordinately regulate estrogen receptor á serine 167 phosphorylation. FEBS Lett. 584, 124-128
-
(2010)
FEBS Lett.
, vol.584
, pp. 124-128
-
-
Yamnik, R.L.1
Holz, M.K.2
-
96
-
-
0037044832
-
Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A
-
DOI 10.1074/jbc.M205501200
-
Wu, J. and Janknecht, R. (2002) Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. J. Biol. Chem. 277, 42669-42679 (Pubitemid 35285636)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.45
, pp. 42669-42679
-
-
Wu, J.1
Janknecht, R.2
-
97
-
-
0034142326
-
c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi
-
Wu, M., Hemesath, T. J., Takemoto, C. M., Horstmann, M. A., Wells, A. G., Price, E. R., Fisher, D. Z. and Fisher, D. E. (2000) c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi. Genes Dev. 14, 301-312 (Pubitemid 30106485)
-
(2000)
Genes and Development
, vol.14
, Issue.3
, pp. 301-312
-
-
Wu, M.1
Hemesath, T.J.2
Takemoto, C.M.3
Horstmann, M.A.4
Wells, A.G.5
Price, E.R.6
Fisher, D.Z.7
Fisher, D.E.8
-
99
-
-
0031007867
-
IκBα is a target for the mitogen-activated 90 kDa ribosomal S6 kinase
-
DOI 10.1093/emboj/16.11.3133
-
Schouten, G. J., Vertegaal, A. C. O., Whiteside, S. T., Israel, A., Toebes, M., Dorsman, J. C., van der Eb, A. J. and Zantema, A. (1997) IκBα is a target for the mitogen-activated 90 kDa ribosomal S6 kinase. EMBO J. 16, 3133-3144 (Pubitemid 27234953)
-
(1997)
EMBO Journal
, vol.16
, Issue.11
, pp. 3133-3144
-
-
Schouten, G.J.1
Vertegaal, A.C.O.2
Whiteside, S.T.3
Israel, A.4
Toebes, M.5
Dorsman, J.C.6
Van Der, E.A.J.7
Zantema, A.8
-
100
-
-
0030851775
-
The 90-kDa ribosomal S6 kinase (pp90(rsk)) phosphorylates the N-terminal regulatory domain of IκBα and stimulates its degradation in vitro
-
DOI 10.1074/jbc.272.34.21281
-
Ghoda, L., Lin, X. and Greene, W. C. (1997) The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IκBα and stimulates its degradation in vitro. J. Biol. Chem. 272, 21281-21288 (Pubitemid 27373994)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.34
, pp. 21281-21288
-
-
Ghoda, L.1
Lin, X.2
Greene, W.C.3
-
101
-
-
33845285529
-
+-induced persistent activation of NF-κB through phosphorylation of IκBβ
-
DOI 10.1152/ajpcell.00552.2005
-
Xu, S., Bayat, H., Hou, X. and Jiang, B. (2006) Ribosomal S6 kinase-1 modulates interleukin-1β-induced persistent activation of NF-κB through phosphorylation of IκBβ. Am. J. Physiol. Cell Physiol. 291, C1336-C1345 (Pubitemid 44878605)
-
(2006)
American Journal of Physiology - Cell Physiology
, vol.291
, Issue.6
-
-
Xu, S.1
Bayat, H.2
Hou, X.3
Jiang, B.4
-
102
-
-
2942716907
-
p53 induces NF-κB activation by an IκB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1
-
DOI 10.1074/jbc.M313509200
-
Bohuslav, J., Chen, L. F., Kwon, H., Mu, Y. and Greene, W. C. (2004) p53 induces NF-κB activation by an IκB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J. Biol. Chem. 279, 26115-26125 (Pubitemid 38798756)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.25
, pp. 26115-26125
-
-
Bohuslav, J.1
Chen, L.-F.2
Kwon, H.3
Mu, Y.4
Greene, W.C.5
-
103
-
-
20144374125
-
A new cellular signaling mechanism for angiotensin II activation of NF-κB: An IκB-independent, RSK-mediated phosphorylation of p65
-
DOI 10.1161/01.ATV.0000164624.00099.e7
-
Zhang, L., Ma, Y., Zhang, J., Cheng, J. and Du, J. (2005) A new cellular signaling mechanism for angiotensin II activation of NF-κB: an IκB-independent, RSK-mediated phosphorylation of p65. Arterioscler. Thromb. Vasc. Biol. 25, 1148-1153 (Pubitemid 40776601)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.6
, pp. 1148-1153
-
-
Zhang, L.1
Ma, Y.2
Zhang, J.3
Cheng, J.4
Du, J.5
-
104
-
-
33744953674
-
The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IκB kinase complex
-
DOI 10.1074/jbc.M512815200
-
Douillette, A., Bibeau-Poirier, A., Gravel, S. P., Clement, J. F., Chenard, V., Moreau, P. and Servant, M. J. (2006) The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IκB kinase complex. J. Biol. Chem. 281, 13275-13284 (Pubitemid 43855239)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.19
, pp. 13275-13284
-
-
Douillette, A.1
Bibeau-Poirier, A.2
Gravel, S.-P.3
Clement, J.-F.4
Chenard, V.5
Moreau, P.6
Servant, M.J.7
-
105
-
-
0000631273
-
The signal-dependent coactivator CBP is a nuclear target for pp90(RSK)
-
DOI 10.1016/S0092-8674(00)80119-1
-
Nakajima, T., Fukamizu, A., Takahashi, J., Gage, F. H., Fisher, T., Blenis, J. and Montminy, M. R. (1996) The signal-dependent coactivator CBP is a nuclear target for pp90RSK. Cell 86, 465-474 (Pubitemid 26272086)
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 465-474
-
-
Nakajima, T.1
Fukamizu, A.2
Takahashi, J.3
Gage, F.H.4
Fisher, T.5
Blenis, J.6
Montminy, M.R.7
-
106
-
-
0037500306
-
RSK
-
DOI 10.1074/jbc.M209108200
-
Wang, Z., Zhang, B., Wang, M. and Carr, B. I. (2003) Persistent ERK phosphorylation negatively regulates cAMP response element-binding protein (CREB) activity via recruitment of CREB-binding protein to pp90RSK. J. Biol. Chem. 278, 11138-11144 (Pubitemid 36792667)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11138-11144
-
-
Wang, Z.1
Zhang, B.2
Wang, M.3
Carr, B.I.4
-
107
-
-
11144357428
-
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology: Implication for Coffin-Lowry syndrome
-
DOI 10.1016/S0092-8674(04)00344-7, PII S0092867404003447
-
Yang, X., Matsuda, K., Bialek, P., Jacquot, S., Masuoka, H. C., Schinke, T., Li, L., Brancorsini, S., Sassone-Corsi, P., Townes, T. M. et al. (2004) ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117, 387-398 (Pubitemid 38534544)
-
(2004)
Cell
, vol.117
, Issue.3
, pp. 387-398
-
-
Yang, X.1
Matsuda, K.2
Bialek, P.3
Jacquot, S.4
Masuoka, H.C.5
Schinke, T.6
Li, L.7
Brancorsini, S.8
Sassone-Corsi, P.9
Townes, T.M.10
Hanauer, A.11
Karsenty, G.12
-
108
-
-
17144376084
-
The serine/threonine protein kinase, p90 ribosomal S6 kinase, is an important regulator of prostate cancer cell proliferation
-
Clark, D. E., Errington, T. M., Smith, J. A., Frierson, Jr, H. F., Weber, M. J. and Lannigan, D. A. (2005) The serine/threonine protein kinase, p90 ribosomal s6 kinase, is an important regulator of prostate cancer cell proliferation. Cancer Res. 65, 3108-3116 (Pubitemid 40524591)
-
(2005)
Cancer Research
, vol.65
, Issue.8
, pp. 3108-3116
-
-
Clark, D.E.1
Errington, T.M.2
Smith, J.A.3
Frierson Jr., H.F.4
Weber, M.J.5
Lannigan, D.A.6
-
109
-
-
0029937701
-
Phosphorylation of c-Fos at the C-terminus enhances its transforming activity
-
Chen, R. H., Juo, P. C., Curran, T. and Blenis, J. (1996) Phosphorylation of c-Fos at the C-terminus enhances its transforming activity. Oncogene 12, 1493-1502 (Pubitemid 26132036)
-
(1996)
Oncogene
, vol.12
, Issue.7
, pp. 1493-1502
-
-
Chen, R.-H.1
Juo, P.C.-H.2
Curran, T.3
Blenis, J.4
-
110
-
-
0036051342
-
Molecular interpretation of ERK signal duration by immediate early gene products
-
Murphy, L. O., Smith, S., Chen, R. H., Fingar, D. C. and Blenis, J. (2002) Molecular interpretation of ERK signal duration by immediate early gene products. Nat. Cell Biol. 4, 556-564
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 556-564
-
-
Murphy, L.O.1
Smith, S.2
Chen, R.H.3
Fingar, D.C.4
Blenis, J.5
-
111
-
-
1542677089
-
Kip1at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization
-
Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization. J. Biol. Chem. 278, 49254-49260
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49254-49260
-
-
Fujita, N.1
Sato, S.2
Tsuruo, T.3
-
112
-
-
67249107699
-
Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility
-
Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility. Proc. Natl. Acad. Sci. U.S.A. 106, 9268-9273
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 9268-9273
-
-
Larrea, M.D.1
Hong, F.2
Wander, S.A.3
Da Silva, T.G.4
Helfman, D.5
Lannigan, D.6
Smith, J.A.7
Slingerland, J.M.8
-
113
-
-
0027515127
-
Inactivation of glycogen synthase kinase-3β by phosphorylation: New kinase connections in insulin and growth-factor signalling
-
Sutherland, C., Leighton, I. A. and Cohen, P. (1993) Inactivation of glycogen synthase kinase-3 β by phosphorylation: new kinase connections in insulin and growth-factor signalling. Biochem. J. 296, 15-19 (Pubitemid 23344723)
-
(1993)
Biochemical Journal
, vol.296
, Issue.1
, pp. 15-19
-
-
Sutherland, C.1
Leighton, I.A.2
Cohen, P.3
-
115
-
-
44349134920
-
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1
-
DOI 10.1073/pnas.0802785105
-
Zhu, J., Blenis, J. and Yuan, J. (2008) Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1. Proc. Natl. Acad. Sci. U.S.A. 105, 6584-6589 (Pubitemid 351754550)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.18
, pp. 6584-6589
-
-
Zhu, J.1
Blenis, J.2
Yuan, J.3
-
116
-
-
77953810437
-
RSK2 is a kinetochore-associated protein that participates in the spindle assembly checkpoint
-
Vigneron, S., Brioudes, E., Burgess, A., Labbe, J. C., Lorca, T. and Castro, A. (2010) RSK2 is a kinetochore-associated protein that participates in the spindle assembly checkpoint. Oncogene 29, 3566-3574
-
(2010)
Oncogene
, vol.29
, pp. 3566-3574
-
-
Vigneron, S.1
Brioudes, E.2
Burgess, A.3
Labbe, J.C.4
Lorca, T.5
Castro, A.6
-
117
-
-
0035375261
-
433, is essential for LKB1 to suppress cell growth
-
433, is essential for LKB1 to suppress cell growth. J. Biol. Chem. 276, 19469-19482
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19469-19482
-
-
Sapkota, G.P.1
Kieloch, A.2
Lizcano, J.M.3
Lain, S.4
Arthur, J.S.5
Williams, M.R.6
Morrice, N.7
Deak, M.8
Alessi, D.R.9
-
118
-
-
58649110598
-
Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
-
Zheng, B., Jeong, J. H., Asara, J. M., Yuan, Y. Y., Granter, S. R., Chin, L. and Cantley, L. C. (2009) Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation. Mol. Cell 33, 237-247
-
(2009)
Mol. Cell
, vol.33
, pp. 237-247
-
-
Zheng, B.1
Jeong, J.H.2
Asara, J.M.3
Yuan, Y.Y.4
Granter, S.R.5
Chin, L.6
Cantley, L.C.7
-
119
-
-
0034693239
-
Cloning and characterization of Xenopus Rsk2, the predominant p90 Rsk isozyme in oocytes and eggs
-
Bhatt, R. R. and Ferrell, Jr, J. E. (2000) Cloning and characterization of Xenopus Rsk2, the predominant p90 Rsk isozyme in oocytes and eggs. J. Biol. Chem. 275, 32983-32990
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32983-32990
-
-
Bhatt, R.R.1
Ferrell Jr., J.E.2
-
120
-
-
0037096157
-
Signalling pathways in oocyte meiotic maturation
-
Schmitt, A. and Nebreda, A. R. (2002) Signalling pathways in oocyte meiotic maturation. J. Cell Sci. 115, 2457-2459 (Pubitemid 34778062)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.12
, pp. 2457-2459
-
-
Schmitt, A.1
Nebreda, A.R.2
-
123
-
-
77951146213
-
A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry
-
Ruiz, E. J., Vilar, M. and Nebreda, A. R. (2010) A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry. Curr. Biol. 20, 717-723
-
(2010)
Curr. Biol.
, vol.20
, pp. 717-723
-
-
Ruiz, E.J.1
Vilar, M.2
Nebreda, A.R.3
-
124
-
-
78650575241
-
Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation
-
Wang, R., Jung, S. Y., Wu, C. F., Qin, J., Kobayashi, R., Gallick, G. E. and Kuang, J. (2010) Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation. Proc. Natl. Acad. Sci. U.S.A. 107, 19885-19890
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 19885-19890
-
-
Wang, R.1
Jung, S.Y.2
Wu, C.F.3
Qin, J.4
Kobayashi, R.5
Gallick, G.E.6
Kuang, J.7
-
125
-
-
0032695982
-
The protein kinase p90 rsk as an essential mediator of cytostatic factor activity
-
Bhatt, R. R. and Ferrell, Jr, J. E. (1999) The protein kinase p90 rsk as an essential mediator of cytostatic factor activity. Science 286, 1362-1365
-
(1999)
Science
, vol.286
, pp. 1362-1365
-
-
Bhatt, R.R.1
Ferrell Jr., J.E.2
-
127
-
-
0035121897
-
Rskduring Xenopus oocyte maturation
-
Rsk during Xenopus oocyte maturation. Curr. Biol. 11, 141-150
-
(2001)
Curr. Biol.
, vol.11
, pp. 141-150
-
-
Schwab, M.S.1
Roberts, B.T.2
Gross, S.D.3
Tunquist, B.J.4
Taieb, F.E.5
Lewellyn, A.L.6
Maller, J.L.7
-
128
-
-
0037172662
-
The spindle checkpoint kinase Bub1 and cyclin E/Cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor
-
DOI 10.1016/S0960-9822(02)00894-1, PII S0960982202008941
-
Tunquist, B. J., Schwab, M. S., Chen, L. G. and Maller, J. L. (2002) The spindle checkpoint kinase Bub1 and cyclin E/Cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor. Curr. Biol. 12, 1027-1033 (Pubitemid 34703335)
-
(2002)
Current Biology
, vol.12
, Issue.12
, pp. 1027-1033
-
-
Tunquist, B.J.1
Schwab, M.S.2
Chen, L.G.3
Maller, J.L.4
-
129
-
-
36749078082
-
Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A
-
DOI 10.1073/pnas.0707537104
-
Wu, J. Q., Hansen, D. V., Guo, Y., Wang, M. Z., Tang, W., Freel, C. D., Tung, J. J., Jackson, P. K. and Kornbluth, S. (2007) Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Proc. Natl. Acad. Sci. U.S.A. 104, 16564-16569 (Pubitemid 350211058)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.42
, pp. 16564-16569
-
-
Wu, J.Q.1
Hansen, D.V.2
Guo, Y.3
Wang, M.Z.4
Tang, W.5
Freel, C.D.6
Tung, J.J.7
Jackson, P.K.8
Kornbluth, S.9
-
130
-
-
34247600518
-
A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs
-
DOI 10.1038/nature05688, PII NATURE05688
-
Inoue, D., Ohe, M., Kanemori, Y., Nobui, T. and Sagata, N. (2007) A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs. Nature 446, 1100-1104 (Pubitemid 46676048)
-
(2007)
Nature
, vol.446
, Issue.7139
, pp. 1100-1104
-
-
Inoue, D.1
Ohe, M.2
Kanemori, Y.3
Nobui, T.4
Sagata, N.5
-
131
-
-
34247586577
-
rsk is required for cytostatic factor arrest in Xenopus laevis eggs
-
rsk is required for cytostatic factor arrest in Xenopus laevis eggs. Nature 446, 1096-1099
-
(2007)
Nature
, vol.446
, pp. 1096-1099
-
-
Nishiyama, T.1
Ohsumi, K.2
Kishimoto, T.3
-
132
-
-
34548548518
-
Ribosomal S6 kinase 2 is a key regulator in tumor promoter-induced cell transformation
-
DOI 10.1158/0008-5472.CAN-06-4668
-
Cho, Y. Y., Yao, K., Kim, H. G., Kang, B. S., Zheng, D., Bode, A. M. and Dong, Z. (2007) Ribosomal s6 kinase 2 is a key regulator in tumor promoter induced cell transformation. Cancer Res. 67, 8104-8112 (Pubitemid 47395145)
-
(2007)
Cancer Research
, vol.67
, Issue.17
, pp. 8104-8112
-
-
Cho, Y.-Y.1
Yao, K.2
Kim, H.-G.3
Bong, S.K.4
Zheng, D.5
Bode, A.M.6
Dong, Z.7
-
133
-
-
33846849470
-
RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer
-
DOI 10.1038/sj.onc.1209827, PII 1209827
-
Bignone, P. A., Lee, K. Y., Liu, Y., Emilion, G., Finch, J., Soosay, A. E., Charnock, F. M., Beck, S., Dunham, I., Mungall, A. J. and Ganesan, T. S. (2007) RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer. Oncogene 26, 683-700 (Pubitemid 46204248)
-
(2007)
Oncogene
, vol.26
, Issue.5
, pp. 683-700
-
-
Bignone, P.A.1
Lee, K.Y.2
Liu, Y.3
Emilion, G.4
Finch, J.5
Soosay, A.E.R.6
Charnock, F.M.L.7
Beck, S.8
Dunham, I.9
Mungall, A.J.10
Ganesan, T.S.11
-
134
-
-
51649086495
-
Anti-invasive and antimetastatic activities of ribosomal protein S6 kinase 4 in breast cancer cells
-
Thakur, A., Sun, Y., Bollig, A., Wu, J., Biliran, H., Banerjee, S., Sarkar, F. H. and Liao, D. J. (2008) Anti-invasive and antimetastatic activities of ribosomal protein S6 kinase 4 in breast cancer cells. Clin. Cancer Res. 14, 4427-4436
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4427-4436
-
-
Thakur, A.1
Sun, Y.2
Bollig, A.3
Wu, J.4
Biliran, H.5
Banerjee, S.6
Sarkar, F.H.7
Liao, D.J.8
-
135
-
-
2942529468
-
Characterization of mouse Rsk4 as an inhibitor of fibroblast growth factor-RAS-extracellular signal-regulated kinase signaling
-
DOI 10.1128/MCB.24.10.4255-4266.2004
-
Myers, A. P., Corson, L. B., Rossant, J. and Baker, J. C. (2004) Characterization of mouse Rsk4 as an inhibitor of fibroblast growth factor-RAS-extracellular signalregulated kinase signaling. Mol. Cell. Biol. 24, 4255-4266 (Pubitemid 41070997)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.10
, pp. 4255-4266
-
-
Myers, A.P.1
Corson, L.B.2
Rossant, J.3
Baker, J.C.4
-
136
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
DOI 10.1038/nature02371
-
Berns, K., Hijmans, E. M., Mullenders, J., Brummelkamp, T. R., Velds, A., Heimerikx, M., Kerkhoven, R. M., Madiredjo, M., Nijkamp, W., Weigelt, B. et al. (2004) A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428, 431-437 (Pubitemid 38419689)
-
(2004)
Nature
, vol.428
, Issue.6981
, pp. 431-437
-
-
Berns, K.1
Hijmans, E.M.2
Mullenders, J.3
Brummelkamp, T.R.4
Velds, A.5
Heimerikx, M.6
Kerkhoven, R.M.7
Madlredjo, M.8
Nijkamp, W.9
Weigelt, B.10
Agami, R.11
Ge, W.12
Cavet, G.13
Linsley, P.S.14
Beijersbergen, R.L.15
Bernards, R.16
-
137
-
-
68049102317
-
Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors
-
Lopez-Vicente, L., Armengol, G., Pons, B., Coch, L., Argelaguet, E., Lleonart, M., Hernandez-Losa, J., de Torres, I. and Ramon y Cajal, S. (2009) Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors. Clin. Cancer Res. 15, 4546-4553
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 4546-4553
-
-
Lopez-Vicente, L.1
Armengol, G.2
Pons, B.3
Coch, L.4
Argelaguet, E.5
Lleonart, M.6
Hernandez-Losa, J.7
De Torres, I.8
Ramon Y Cajal, S.9
-
139
-
-
17444431201
-
Phosphorylation and functional inactivation of TSC2 by Erk: Implications for tuberous sclerosis and cancer pathogenesis
-
DOI 10.1016/j.cell.2005.02.031
-
Ma, L., Chen, Z., Erdjument-Bromage, H., Tempst, P. and Pandolfi, P. P. (2005) Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell 121, 179-193 (Pubitemid 40546387)
-
(2005)
Cell
, vol.121
, Issue.2
, pp. 179-193
-
-
Ma, L.1
Chen, Z.2
Erdjument-Bromage, H.3
Tempst, P.4
Pandolfi, P.P.5
-
140
-
-
4544384577
-
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
-
DOI 10.1073/pnas.0405659101
-
Roux, P. P., Ballif, B. A., Anjum, R., Gygi, S. P. and Blenis, J. (2004) Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. Proc. Natl. Acad. Sci. U.S.A. 101, 13489-13494 (Pubitemid 39238430)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.37
, pp. 13489-13494
-
-
Roux, P.P.1
Ballif, B.A.2
Anjum, R.3
Gygi, S.P.4
Blenis, J.5
-
141
-
-
21744446249
-
Activation of protein synthesis in cardiomyocytes by the hypertrophic
-
DOI 10.1042/BJ20041888
-
Rolfe, M., McLeod, L. E., Pratt, P. F. and Proud, C. G. (2005) Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2). Biochem. J. 388, 973-984 (Pubitemid 40941586)
-
(2005)
Biochemical Journal
, vol.388
, Issue.3
, pp. 973-984
-
-
Rolfe, M.1
McLeod, L.E.2
Pratt, P.F.3
Proud, C.G.4
-
142
-
-
51049083138
-
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation
-
Carriere, A., Cargnello, M., Julien, L. A., Gao, H., Bonneil, E., Thibault, P. and Roux, P. P. (2008) Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation. Curr. Biol. 18, 1269-1277
-
(2008)
Curr. Biol.
, vol.18
, pp. 1269-1277
-
-
Carriere, A.1
Cargnello, M.2
Julien, L.A.3
Gao, H.4
Bonneil, E.5
Thibault, P.6
Roux, P.P.7
-
143
-
-
0037109062
-
535in the ε-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin
-
535 in the ε-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin. Biochem. J. 367, 475-481
-
(2002)
Biochem. J.
, vol.367
, pp. 475-481
-
-
Wang, X.1
Janmaat, M.2
Beugnet, A.3
Paulin, F.E.4
Proud, C.G.5
-
144
-
-
0345167800
-
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
-
DOI 10.1016/S0092-8674(03)00929-2
-
Inoki, K., Zhu, T. and Guan, K. L. (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115, 577-590 (Pubitemid 37506046)
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.-L.3
-
145
-
-
33748153690
-
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
-
DOI 10.1016/j.cell.2006.06.055, PII S0092867406010166
-
Inoki, K., Ouyang, H., Zhu, T., Lindvall, C., Wang, Y., Zhang, X., Yang, Q., Bennett, C., Harada, Y., Stankunas, K. et al. (2006) TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 126, 955-968 (Pubitemid 44310775)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 955-968
-
-
Inoki, K.1
Ouyang, H.2
Zhu, T.3
Lindvall, C.4
Wang, Y.5
Zhang, X.6
Yang, Q.7
Bennett, C.8
Harada, Y.9
Stankunas, K.10
Wang, C.-y.11
He, X.12
MacDougald, O.A.13
You, M.14
Williams, B.O.15
Guan, K.-L.16
-
147
-
-
33745570504
-
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
-
DOI 10.1038/sj.emboj.7601166, PII 7601166
-
Shahbazian, D., Roux, P. P., Mieulet, V., Cohen, M. S., Raught, B., Taunton, J., Hershey, J. W., Blenis, J., Pende, M. and Sonenberg, N. (2006) The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. EMBO J. 25, 2781-2791 (Pubitemid 43980385)
-
(2006)
EMBO Journal
, vol.25
, Issue.12
, pp. 2781-2791
-
-
Shahbazian, D.1
Roux, P.P.2
Mieulet, V.3
Cohen, M.S.4
Raught, B.5
Taunton, J.6
Hershey, J.W.B.7
Blenis, J.8
Pende, M.9
Sonenberg, N.10
-
148
-
-
77749323441
-
Control of cell survival and proliferation by mammalian eukaryotic initiation factor 4B
-
Shahbazian, D., Parsyan, A., Petroulakis, E., Topisirovic, I., Martineau, Y., Gibbs, B. F., Svitkin, Y. and Sonenberg, N. (2010) Control of cell survival and proliferation by mammalian eukaryotic initiation factor 4B. Mol. Cell. Biol. 30, 1478-1485
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1478-1485
-
-
Shahbazian, D.1
Parsyan, A.2
Petroulakis, E.3
Topisirovic, I.4
Martineau, Y.5
Gibbs, B.F.6
Svitkin, Y.7
Sonenberg, N.8
-
149
-
-
78651397868
-
Regulatory effects of ribosomal S6 kinase 1 (RSK1) in IFNλsignaling
-
Kroczynska, B., Joshi, S., Eklund, E. A., Verma, A., Kotenko, S. V., Fish, E. N. and Platanias, L. C. (2011) Regulatory effects of ribosomal S6 kinase 1 (RSK1) in IFNλsignaling. J. Biol. Chem. 286, 1147-1156
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 1147-1156
-
-
Kroczynska, B.1
Joshi, S.2
Eklund, E.A.3
Verma, A.4
Kotenko, S.V.5
Fish, E.N.6
Platanias, L.C.7
-
150
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcriptiondependent and -independent mechanisms
-
Bonni, A., Brunet, A., West, A. E., Datta, S. R., Takasu, M. A. and Greenberg, M. E. (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcriptiondependent and -independent mechanisms. Science 286, 1358-1362
-
(1999)
Science
, vol.286
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
151
-
-
27944454010
-
Dual pathways for nuclear factor κB activation by angiotensin II in vascular smooth muscle: Phosphorylation of p65 by IκB kinase and ribosomal kinase
-
DOI 10.1161/01.RES.0000190589.52286.41
-
Zhang, L., Cheng, J., Ma, Y., Thomas, W., Zhang, J. and Du, J. (2005) Dual pathways for nuclear factor κB activation by angiotensin II in vascular smooth muscle: phosphorylation of p65 by IκB kinase and ribosomal kinase. Circ. Res. 97, 975-982 (Pubitemid 41668910)
-
(2005)
Circulation Research
, vol.97
, Issue.10
, pp. 975-982
-
-
Zhang, L.1
Cheng, J.2
Ma, Y.3
Thomas, W.4
Zhang, J.5
Du, J.6
-
152
-
-
0034740214
-
C/EBPβ phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival
-
DOI 10.1016/S1097-2765(01)00374-4
-
Buck, M., Poli, V., Hunter, T. and Chojkier, M. (2001) C/EBPβ phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival. Mol. Cell 8, 807-816 (Pubitemid 33030214)
-
(2001)
Molecular Cell
, vol.8
, Issue.4
, pp. 807-816
-
-
Buck, M.1
Poli, V.2
Hunter, T.3
Chojkier, M.4
-
153
-
-
0034628612
-
Rsk1 mediates a MEK-MAP kinase cell survival signal
-
DOI 10.1016/S0960-9822(00)00310-9
-
Shimamura, A., Ballif, B. A., Richards, S. A. and Blenis, J. (2000) Rsk1 mediates a MEK-MAP kinase cell survival signal. Curr. Biol. 10, 127-135 (Pubitemid 30115743)
-
(2000)
Current Biology
, vol.10
, Issue.3
, pp. 127-135
-
-
Shimamura, A.1
Ballif, B.A.2
Richards, S.A.3
Blenis, J.4
-
154
-
-
3042515471
-
DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death
-
DOI 10.1016/j.semcancer.2004.04.008, PII S1044579X04000252
-
Bialik, S. and Kimchi, A. (2004) DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death. Semin. Cancer Biol. 14, 283-294 (Pubitemid 38824589)
-
(2004)
Seminars in Cancer Biology
, vol.14
, Issue.4
, pp. 283-294
-
-
Bialik, S.1
Kimchi, A.2
-
155
-
-
26244449244
-
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling
-
DOI 10.1016/j.cub.2005.08.050, PII S0960982205009693
-
Anjum, R., Roux, P. P., Ballif, B. A., Gygi, S. P. and Blenis, J. (2005) The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling. Curr. Biol. 15, 1762-1767 (Pubitemid 41415634)
-
(2005)
Current Biology
, vol.15
, Issue.19
, pp. 1762-1767
-
-
Anjum, R.1
Roux, P.P.2
Ballif, B.A.3
Gygi, S.P.4
Blenis, J.5
-
156
-
-
1642293247
-
Ribosomal S6 Kinase (RSK) Regulates Phosphorylation of Filamin A on an Important Regulatory Site
-
DOI 10.1128/MCB.24.7.3025-3035.2004
-
Woo, M. S., Ohta, Y., Rabinovitz, I., Stossel, T. P. and Blenis, J. (2004) Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin a on an important regulatory site. Mol. Cell. Biol. 24, 3025-3035 (Pubitemid 38381290)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.7
, pp. 3025-3035
-
-
Woo, M.S.1
Ohta, Y.2
Rabinovitz, I.3
Stossel, T.P.4
Blenis, J.5
-
157
-
-
0036711657
-
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1
-
DOI 10.1038/ncb838
-
Vadlamudi, R. K., Li, F., Adam, L., Nguyen, D., Ohta, Y., Stossel, T. P. and Kumar, R. (2002) Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1. Nat. Cell Biol. 4, 681-690 (Pubitemid 34993704)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 681-690
-
-
Vadlamudi, R.K.1
Li, F.2
Adam, L.3
Nguyen, D.4
Ohta, Y.5
Stossel, T.P.6
Kumar, R.7
-
158
-
-
78649872212
-
A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration
-
Smolen, G. A., Zhang, J., Zubrowski, M. J., Edelman, E. J., Luo, B., Yu, M., Ng, L. W., Scherber, C. M., Schott, B. J., Ramaswamy, S. et al. (2010) A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration. Genes Dev. 24, 2654-2665
-
(2010)
Genes Dev.
, vol.24
, pp. 2654-2665
-
-
Smolen, G.A.1
Zhang, J.2
Zubrowski, M.J.3
Edelman, E.J.4
Luo, B.5
Yu, M.6
Ng, L.W.7
Scherber, C.M.8
Schott, B.J.9
Ramaswamy, S.10
-
159
-
-
79955099790
-
SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation
-
Tanimura, S., Hashizume, J., Kurosaki, Y., Sei, K., Gotoh, A., Ohtake, R., Kawano, M., Watanabe, K. and Kohno, M. (2011) SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation. Genes Cells 16, 514-526
-
(2011)
Genes Cells
, vol.16
, pp. 514-526
-
-
Tanimura, S.1
Hashizume, J.2
Kurosaki, Y.3
Sei, K.4
Gotoh, A.5
Ohtake, R.6
Kawano, M.7
Watanabe, K.8
Kohno, M.9
-
161
-
-
33846497923
-
p90 RSK-1 associates with and inhibits neuronal nitric oxide synthase
-
DOI 10.1042/BJ20060580
-
Song, T., Sugimoto, K., Ihara, H., Mizutani, A., Hatano, N., Kume, K., Kambe, T., Yamaguchi, F., Tokuda, M. and Watanabe, Y. (2007) p90 RSK-1 associates with and inhibits neuronal nitric oxide synthase. Biochem. J. 401, 391-398 (Pubitemid 46166421)
-
(2007)
Biochemical Journal
, vol.401
, Issue.2
, pp. 391-398
-
-
Song, T.1
Sugimoto, K.2
Ihara, H.3
Mizutani, A.4
Hatano, N.5
Kume, K.6
Kambe, T.7
Yamaguchi, F.8
Tokuda, M.9
Watanabe, Y.10
-
162
-
-
0033575236
-
+ exchanger isoform-1
-
+ exchanger isoform-1. J. Biol. Chem. 274, 20206-20214
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20206-20214
-
-
Takahashi, E.1
Abe, J.2
Gallis, B.3
Aebersold, R.4
Spring, D.J.5
Krebs, E.G.6
Berk, B.C.7
-
163
-
-
38949159953
-
Ran-Binding Protein 3 Phosphorylation Links the Ras and PI3-Kinase Pathways to Nucleocytoplasmic Transport
-
DOI 10.1016/j.molcel.2007.12.024, PII S1097276508000671
-
Yoon, S. O., Shin, S., Liu, Y., Ballif, B. A., Woo, M. S., Gygi, S. P. and Blenis, J. (2008) Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport. Mol. Cell 29, 362-375 (Pubitemid 351215938)
-
(2008)
Molecular Cell
, vol.29
, Issue.3
, pp. 362-375
-
-
Yoon, S.-O.1
Shin, S.2
Liu, Y.3
Ballif, B.A.4
Woo, M.S.5
Gygi, S.P.6
Blenis, J.7
-
164
-
-
62649113168
-
Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells
-
Stratford, A. L., Fry, C. J., Desilets, C., Davies, A. H., Cho, Y. Y., Li, Y., Dong, Z., Berquin, I. M., Roux, P. P. and Dunn, S. E. (2008) Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells. Breast Cancer Res. 10, R99
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Stratford, A.L.1
Fry, C.J.2
Desilets, C.3
Davies, A.H.4
Cho, Y.Y.5
Li, Y.6
Dong, Z.7
Berquin, I.M.8
Roux, P.P.9
Dunn, S.E.10
-
165
-
-
35048903018
-
Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR
-
DOI 10.1042/BJ20070649
-
Geraghty, K. M., Chen, S., Harthill, J. E., Ibrahim, A. F., Toth, R., Morrice, N. A., Vandermoere, F., Moorhead, G. B., Hardie, D. G. and MacKintosh, C. (2007) Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR. Biochem. J. 407, 231-241 (Pubitemid 47556988)
-
(2007)
Biochemical Journal
, vol.407
, Issue.2
, pp. 231-241
-
-
Geraghty, K.M.1
Chen, S.2
Harthill, J.E.3
Ibrahim, A.F.4
Toth, R.5
Morrice, N.A.6
Vandermoere, F.7
Moorhead, G.B.8
Hardie, D.G.9
MacKintosh, C.10
-
166
-
-
0030767442
-
EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2
-
Douville, E. and Downward, J. (1997) EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2. Oncogene 15, 373-383 (Pubitemid 27370986)
-
(1997)
Oncogene
, vol.15
, Issue.4
, pp. 373-383
-
-
Douville, E.1
Downward, J.2
-
167
-
-
0034747717
-
Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice
-
Dufresne, S. D., Bjorbaek, C., El-Haschimi, K., Zhao, Y., Aschenbach, W. G., Moller, D. E. and Goodyear, L. J. (2001) Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice. Mol. Cell. Biol. 21, 81-87
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 81-87
-
-
Dufresne, S.D.1
Bjorbaek, C.2
El-Haschimi, K.3
Zhao, Y.4
Aschenbach, W.G.5
Moller, D.E.6
Goodyear, L.J.7
-
168
-
-
0029832136
-
Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome
-
DOI 10.1038/384567a0
-
Trivier, E., De Cesare, D., Jacquot, S., Pannetier, S., Zackai, E., Young, I., Mandel, J. L., Sassone-Corsi, P. and Hanauer, A. (1996) Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome. Nature 384, 567-570 (Pubitemid 26415934)
-
(1996)
Nature
, vol.384
, Issue.6609
, pp. 567-570
-
-
Trivier, E.1
De Cesare, D.2
Jacquot, S.3
Pannetier, S.4
Zackai, E.5
Young, I.6
Mandel, J.-L.7
Sassone-Corsi, P.8
Hanauer, A.9
-
169
-
-
77952668959
-
Coffin-Lowry syndrome
-
Pereira, P. M., Schneider, A., Pannetier, S., Heron, D. and Hanauer, A. (2010) Coffin-Lowry syndrome. Eur. J. Hum. Genet. 18, 627-633
-
(2010)
Eur. J. Hum. Genet.
, vol.18
, pp. 627-633
-
-
Pereira, P.M.1
Schneider, A.2
Pannetier, S.3
Heron, D.4
Hanauer, A.5
-
170
-
-
33847661648
-
Altered neurodevelopment associated with mutations of RSK2: A morphometric MRI study of Coffin-Lowry syndrome
-
DOI 10.1007/s10048-007-0080-6
-
Kesler, S. R., Simensen, R. J., Voeller, K., Abidi, F., Stevenson, R. E., Schwartz, C. E. and Reiss, A. L. (2007) Altered neurodevelopment associated with mutations of RSK2: a morphometric MRI study of Coffin-Lowry syndrome. Neurogenetics 8, 143-147 (Pubitemid 46356252)
-
(2007)
Neurogenetics
, vol.8
, Issue.2
, pp. 143-147
-
-
Kesler, S.R.1
Simensen, R.J.2
Voeller, K.3
Abidi, F.4
Stevenson, R.E.5
Schwartz, C.E.6
Reiss, A.L.7
-
171
-
-
0035145479
-
Mutations in the X-linked RSK2 gene (RPS6KA3) in patients with Coffin-Lowry syndrome
-
DOI 10.1002/1098-1004(200102)17:2<103::AID-HUMU2>3.0.CO;2-N
-
Delaunoy, J., Abidi, F., Zeniou, M., Jacquot, S., Merienne, K., Pannetier, S., Schmitt, M., Schwartz, C. and Hanauer, A. (2001) Mutations in the X-linked RSK2 gene (RPS6KA3) in patients with Coffin-Lowry syndrome. Hum. Mutat. 17, 103-116 (Pubitemid 32120712)
-
(2001)
Human Mutation
, vol.17
, Issue.2
, pp. 103-116
-
-
Delaunoy, J.-P.1
Abidi, F.2
Zeniou, M.3
Jacquot, S.4
Merienne, K.5
Pannetier, S.6
Schmitt, M.7
Schwartz, C.E.8
Hanauer, A.9
-
172
-
-
33846437448
-
Deletion of the Coffin-Lowry syndrome gene Rsk2 in mice is associated with impaired spatial learning and reduced control of exploratory behavior
-
DOI 10.1007/s10519-006-9116-1
-
Poirier, R., Jacquot, S., Vaillend, C., Soutthiphong, A. A., Libbey, M., Davis, S., Laroche, S., Hanauer, A., Welzl, H., Lipp, H. P. and Wolfer, D. P. (2007) Deletion of the Coffin-Lowry syndrome gene Rsk2 in mice is associated with impaired spatial learning and reduced control of exploratory behavior. Behav. Genet. 37, 31-50 (Pubitemid 46144051)
-
(2007)
Behavior Genetics
, vol.37
, Issue.1
, pp. 31-50
-
-
Poirier, R.1
Jacquot, S.2
Vaillend, C.3
Soutthiphong, A.A.4
Libbey, M.5
Davis, S.6
Laroche, S.7
Hanauer, A.8
Welzl, H.9
Lipp, H.-P.10
Wolfer, D.P.11
-
173
-
-
77957922490
-
Coffin-Lowry syndrome: A role for RSK2 in mammalian neurogenesis
-
Dugani, C. B., Paquin, A., Kaplan, D. R. and Miller, F. D. (2010) Coffin-Lowry syndrome: a role for RSK2 in mammalian neurogenesis. Dev. Biol. 347, 348-359
-
(2010)
Dev. Biol.
, vol.347
, pp. 348-359
-
-
Dugani, C.B.1
Paquin, A.2
Kaplan, D.R.3
Miller, F.D.4
-
174
-
-
7744236541
-
The S6KII(rsk) gene of Drosophila melanogaster differentially affects an operant and a classical learning task
-
DOI 10.1523/JNEUROSCI.3211-04.2004
-
Putz, G., Bertolucci, F., Raabe, T., Zars, T. and Heisenberg, M. (2004) The S6KII (rsk) gene of Drosophila melanogaster differentially affects an operant and a classical learning task. J. Neurosci. 24, 9745-9751 (Pubitemid 39463555)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.44
, pp. 9745-9751
-
-
Putz, G.1
Bertolucci, F.2
Raabe, T.3
Zars, T.4
Heisenberg, M.5
-
175
-
-
0038660080
-
Insulin resistance and lipodystrophy in mice lacking ribosomal S6 kinase 2
-
DOI 10.2337/diabetes.52.6.1340
-
El-Haschimi, K., Dufresne, S. D., Hirshman, M. F., Flier, J. S., Goodyear, L. J. and Bjorbaek, C. (2003) Insulin resistance and lipodystrophy in mice lacking ribosomal S6 kinase 2. Diabetes 52, 1340-1346 (Pubitemid 36666186)
-
(2003)
Diabetes
, vol.52
, Issue.6
, pp. 1340-1346
-
-
El-Haschimi, K.1
Dufresne, S.D.2
Hirshman, M.F.3
Flier, J.S.4
Goodyear, L.J.5
Bjorbaek, C.6
-
177
-
-
77955141736
-
Phenotypic annotation of the mouse X chromosome
-
Cox, B. J., Vollmer, M., Tamplin, O., Lu, M., Biechele, S., Gertsenstein, M., van Campenhout, C., Floss, T., Kuhn, R., Wurst, W. et al. (2010) Phenotypic annotation of the mouse X chromosome. Genome Res. 20, 1154-1164
-
(2010)
Genome Res.
, vol.20
, pp. 1154-1164
-
-
Cox, B.J.1
Vollmer, M.2
Tamplin, O.3
Lu, M.4
Biechele, S.5
Gertsenstein, M.6
Van Campenhout, C.7
Floss, T.8
Kuhn, R.9
Wurst, W.10
-
178
-
-
77956621143
-
Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases
-
Moritz, A., Li, Y., Guo, A., Villen, J., Wang, Y., MacNeill, J., Kornhauser, J., Sprott, K., Zhou, J., Possemato, A. et al. (2010) Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases. Sci. Signal. 3, ra64
-
(2010)
Sci. Signal.
, vol.3
-
-
Moritz, A.1
Li, Y.2
Guo, A.3
Villen, J.4
Wang, Y.5
MacNeill, J.6
Kornhauser, J.7
Sprott, K.8
Zhou, J.9
Possemato, A.10
-
179
-
-
78650209096
-
Paving the way for targeting RSK in cancer
-
Romeo, Y. and Roux, P. P. (2011) Paving the way for targeting RSK in cancer. Expert Opin. Ther. Targets 15, 5-9
-
(2011)
Expert Opin. Ther. Targets
, vol.15
, pp. 5-9
-
-
Romeo, Y.1
Roux, P.P.2
-
180
-
-
0032904850
-
rsk, glycogen synthase kinase 3, and β-catenin in early Xenopus development
-
rsk, glycogen synthase kinase 3, and β-catenin in early Xenopus development. Mol. Cell. Biol. 19, 1427-1437
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1427-1437
-
-
Torres, M.A.1
Eldar-Finkelman, H.2
Krebs, E.G.3
Moon, R.T.4
-
181
-
-
14144254701
-
Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors
-
DOI 10.1073/pnas.0409143102
-
Ballif, B. A., Roux, P. P., Gerber, S. A., MacKeigan, J. P., Blenis, J. and Gygi, S. P. (2005) Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors. Proc. Natl. Acad. Sci. U.S.A. 102, 667-672 (Pubitemid 40282723)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.3
, pp. 667-672
-
-
Ballif, B.A.1
Roux, P.P.2
Gerber, S.A.3
MacKeigan, J.P.4
Blenis, J.5
Gygi, S.P.6
-
182
-
-
18944395541
-
The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells
-
DOI 10.1038/sj.emboj.7600648
-
Cartlidge, R. A., Knebel, A., Peggie, M., Alexandrov, A., Phizicky, E. M. and Cohen, P. (2005) The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells. EMBO J. 24, 1696-1705 (Pubitemid 40704980)
-
(2005)
EMBO Journal
, vol.24
, Issue.9
, pp. 1696-1705
-
-
Cartlidge, R.A.1
Knebel, A.2
Peggie, M.3
Alexandrov, A.4
Phizicky, E.M.5
Cohen, P.6
-
183
-
-
12844286178
-
Recruitment of the extracellular signal-regulated kinase/ribosomal S6 kinase signaling pathway to the NFATc4 transcription activation complex
-
DOI 10.1128/MCB.25.3.907-920.2005
-
Yang, T. T., Xiong, Q., Graef, I. A., Crabtree, G. R. and Chow, C. W. (2005) Recruitment of the extracellular signal-regulated kinase/ribosomal S6 kinase signaling pathway to the NFATc4 transcription activation complex. Mol. Cell. Biol. 25, 907-920 (Pubitemid 40165800)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.3
, pp. 907-920
-
-
Yang, T.T.C.1
Xiong, Q.2
Graef, I.A.3
Crabtree, G.R.4
Chow, C.-W.5
-
184
-
-
34247205281
-
RSK2 mediates muscle cell differentiation through regulation of NFAT3
-
DOI 10.1074/jbc.M611322200
-
Cho, Y. Y., Yao, K., Bode, A. M., Bergen, III, H. R., Madden, B. J., Oh, S. M., Ermakova, S., Kang, B. S., Choi, H. S., Shim, J. H. and Dong, Z. (2007) RSK2 mediates muscle cell differentiation through regulation of NFAT3. J. Biol. Chem. 282, 8380-8392 (Pubitemid 47093615)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.11
, pp. 8380-8392
-
-
Cho, Y.-Y.1
Yao, K.2
Bode, A.M.3
Bergen III, H.R.4
Madden, B.J.5
Oh, S.-M.6
Ermakova, S.7
Bong, S.K.8
Hong, S.C.9
Shim, J.-H.10
Dong, Z.11
-
185
-
-
33751412300
-
ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae
-
DOI 10.1016/j.cmet.2006.10.010, PII S1550413106003391
-
Elefteriou, F., Benson, M. D., Sowa, H., Starbuck, M., Liu, X., Ron, D., Parada, L. F. and Karsenty, G. (2006) ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab. 4, 441-451 (Pubitemid 44817348)
-
(2006)
Cell Metabolism
, vol.4
, Issue.6
, pp. 441-451
-
-
Elefteriou, F.1
Benson, M.D.2
Sowa, H.3
Starbuck, M.4
Liu, X.5
Ron, D.6
Parada, L.F.7
Karsenty, G.8
-
186
-
-
78751482234
-
Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation
-
Liu, K., Cho, Y. Y., Yao, K., Nadas, J., Kim, D. J., Cho, E. J., Lee, M. H., Pugliese, A., Zhang, J., Bode, A. M. and Dong, Z. (2011) Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation. J. Biol. Chem. 286, 2057-2066
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2057-2066
-
-
Liu, K.1
Cho, Y.Y.2
Yao, K.3
Nadas, J.4
Kim, D.J.5
Cho, E.J.6
Lee, M.H.7
Pugliese, A.8
Zhang, J.9
Bode, A.M.10
Dong, Z.11
-
187
-
-
34447326686
-
Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade
-
DOI 10.1111/j.1471-4159.2007.04606.x
-
Wang, Y., Liu, L. and Xia, Z. (2007) Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade. J. Neurochem. 102, 957-966 (Pubitemid 47057305)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.3
, pp. 957-966
-
-
Wang, Y.1
Liu, L.2
Xia, Z.3
-
188
-
-
67649379040
-
p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling
-
Abe, Y., Yoon, S. O., Kubota, K., Mendoza, M. C., Gygi, S. P. and Blenis, J. (2009) p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling. J. Biol. Chem. 284, 14939-14948
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 14939-14948
-
-
Abe, Y.1
Yoon, S.O.2
Kubota, K.3
Mendoza, M.C.4
Gygi, S.P.5
Blenis, J.6
-
189
-
-
23644436379
-
Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL
-
DOI 10.1042/BJ20050733
-
Auld, G. C., Campbell, D. G., Morrice, N. and Cohen, P. (2005) Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL. Biochem. J. 389, 775-783 (Pubitemid 41117337)
-
(2005)
Biochemical Journal
, vol.389
, Issue.3
, pp. 775-783
-
-
Auld, G.C.1
Campbell, D.G.2
Morrice, N.3
Cohen, P.4
|