Evidence that the dephosphorylation of Ser535 in the ε-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin

Biochemical Journal

Volumn 367, Issue 2, 2002, Pages 475-481

  Wang, Xuemin ^a   Janmaat, Maarten ^a   Beugnet, Anne ^a   Paulin, Fiona E M ^a   Proud, Christopher G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Glycogen synthase kinase 3; Mammalian target of rapamycin (mTOR); mRNA translation

Indexed keywords

INSULIN; PROTEINS; SIGNALING; SUBSTRATES;

DEPHOSPHORYLATION;

BIOCHEMISTRY;

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE INHIBITOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INSULIN; LITHIUM CHLORIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SUBUNIT; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CHO CELL; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; ENZYME SUBUNIT; INSULIN METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINOPHENOLS; ANIMALS; BUTADIENES; CHO CELLS; CHROMONES; CRICETINAE; ENZYME INHIBITORS; EUKARYOTIC INITIATION FACTOR-2B; GLYCOGEN SYNTHASE KINASE 3; INDOLES; INSULIN; LITHIUM CHLORIDE; MALEIMIDES; MORPHOLINES; NITRILES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN SUBUNITS; SERINE;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; EUKARYOTA; MAMMALIA;

EID: 0037109062     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020677     Document Type: Article

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