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Volumn 52, Issue 6, 2003, Pages 1340-1346

Insulin resistance and lipodystrophy in mice lacking ribosomal S6 kinase 2

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LEPTIN; PROTEIN SERINE THREONINE KINASE; RIBOSOMAL S6 KINASE 2; UNCLASSIFIED DRUG;

EID: 0038660080     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.6.1340     Document Type: Article
Times cited : (33)

References (64)
  • 1
    • 0040175067 scopus 로고    scopus 로고
    • Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction
    • Frodin M, Gammeltoft S: Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction. Mol Cell Endocrinol 151:65-77, 1999
    • (1999) Mol Cell Endocrinol , vol.151 , pp. 65-77
    • Frodin, M.1    Gammeltoft, S.2
  • 2
    • 0023766145 scopus 로고
    • Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
    • Sturgill TW, Ray LB, Erikson E, Maller JL: Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 334:715-718, 1988
    • (1988) Nature , vol.334 , pp. 715-718
    • Sturgill, T.W.1    Ray, L.B.2    Erikson, E.3    Maller, J.L.4
  • 3
    • 0004905963 scopus 로고
    • A protein kinase from Xenopus eggs specific for ribosomal protein S 6
    • Erikson E, Maller JL: A protein kinase from Xenopus eggs specific for ribosomal protein S6. Proc Natl Acad Sci U S A 82:742-746, 1985
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 742-746
    • Erikson, E.1    Maller, J.L.2
  • 4
    • 0344737208 scopus 로고
    • A Xenopus ribosomal protein S 6 kinase has two apparent kinase domains that are each similar to distinct protein kinases
    • Jones SW, Erikson E, Blenis J, Maller JL, Erikson RL: A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases. Proc Natl Acad Sci U S A 85:3377-3381, 1988
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 3377-3381
    • Jones, S.W.1    Erikson, E.2    Blenis, J.3    Maller, J.L.4    Erikson, R.L.5
  • 6
    • 0027786823 scopus 로고
    • p70s6K/p85s6k: Mechanism of activation, effects of rapamycin and role in mitogenesis
    • Thomas G: p70s6K/p85s6k: mechanism of activation, effects of rapamycin and role in mitogenesis. Biochem Soc Trans 21:901-904, 1993
    • (1993) Biochem Soc Trans , vol.21 , pp. 901-904
    • Thomas, G.1
  • 7
    • 0028217280 scopus 로고
    • Human RSK isoforms: Cloning and characterization of tissue-specific expression
    • Moller DE, Xia CH, Tang W, Zhu AX, Jakubowski M: Human RSK isoforms: cloning and characterization of tissue-specific expression. Am J Physiol 266:C351-C359, 1994
    • (1994) Am J Physiol , vol.266
    • Moller, D.E.1    Xia, C.H.2    Tang, W.3    Zhu, A.X.4    Jakubowski, M.5
  • 8
    • 0029007314 scopus 로고
    • RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: Growth factor-stimulated kinase function and nuclear translocation
    • Zhao Y, Bjørbæk C, Weremowicz S, Morton CC, Moller DE: RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation. Mol Cell Biol 8:4353-4363, 1995
    • (1995) Mol Cell Biol , vol.8 , pp. 4353-4363
    • Zhao, Y.1    Bjørbæk, C.2    Weremowicz, S.3    Morton, C.C.4    Moller, D.E.5
  • 11
    • 0032491440 scopus 로고    scopus 로고
    • RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)
    • Pierrat B, Correia JS, Mary JL, Tomas-Zuber M, Lesslauer W: RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK). J Biol Chem 273:29661-29671, 1998
    • (1998) J Biol Chem , vol.273 , pp. 29661-29671
    • Pierrat, B.1    Correia, J.S.2    Mary, J.L.3    Tomas-Zuber, M.4    Lesslauer, W.5
  • 12
    • 0032479983 scopus 로고    scopus 로고
    • Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38 and may mediate activation of CREB
    • Deak M, Clifton AD, Lucocq LM, Alessi DR: Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38 and may mediate activation of CREB. EMBO J 17:4426-4421, 1998
    • (1998) EMBO J , vol.17 , pp. 4426-4421
    • Deak, M.1    Clifton, A.D.2    Lucocq, L.M.3    Alessi, D.R.4
  • 13
    • 0026608787 scopus 로고
    • Nuclear localisation and regulation of erk-and rsk-encoded protein kinases
    • Chen RH, Sarnecki C, Blenis J: Nuclear localisation and regulation of erk-and rsk-encoded protein kinases. Mol Cell Biol 3:915-927, 1992
    • (1992) Mol Cell Biol , vol.3 , pp. 915-927
    • Chen, R.H.1    Sarnecki, C.2    Blenis, J.3
  • 14
    • 0035805618 scopus 로고    scopus 로고
    • UVA induces Ser381 phosphorylation of p90RSK/MAPKAP-K 1 via ERK and JNK pathways
    • Zhang Y, Zhong S, Dong Z, Chen N, Bode AM, Ma W, Dong Z: UVA induces Ser381 phosphorylation of p90RSK/MAPKAP-K1 via ERK and JNK pathways. J Biol Chem 276:14572-14580, 2001
    • (2001) J Biol Chem , vol.276 , pp. 14572-14580
    • Zhang, Y.1    Zhong, S.2    Dong, Z.3    Chen, N.4    Bode, A.M.5    Ma, W.6    Dong, Z.7
  • 15
    • 0034738964 scopus 로고    scopus 로고
    • Activation of RSK by UV-light: Phosphorylation dynamics and involvement of the MAPK pathway
    • Merienne K, Jacquot S, Zeniou M, Pannetier S, Sassone-Corsi P, Hanauer A: Activation of RSK by UV-light: phosphorylation dynamics and involvement of the MAPK pathway. Oncogene 19:4221-4229, 2000
    • (2000) Oncogene , vol.19 , pp. 4221-4229
    • Merienne, K.1    Jacquot, S.2    Zeniou, M.3    Pannetier, S.4    Sassone-Corsi, P.5    Hanauer, A.6
  • 16
    • 0027385031 scopus 로고
    • A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity
    • Rivera VM, Miranti CK, Misra RP, Ginty DD, Chen RH, Blenis J, Greenberg ME: A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Mol Cell Biol 10:6260-6273, 1993
    • (1993) Mol Cell Biol , vol.10 , pp. 6260-6273
    • Rivera, V.M.1    Miranti, C.K.2    Misra, R.P.3    Ginty, D.D.4    Chen, R.H.5    Blenis, J.6    Greenberg, M.E.7
  • 17
    • 0025924683 scopus 로고
    • Regulation of pp90rsk phosphorylation and S6 phospotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction
    • Chen RH, Chung J, Blenis J: Regulation of pp90rsk phosphorylation and S6 phospotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction. Mol Cell Biol 4:1861-1867, 1991
    • (1991) Mol Cell Biol , vol.4 , pp. 1861-1867
    • Chen, R.H.1    Chung, J.2    Blenis, J.3
  • 18
    • 0037107414 scopus 로고    scopus 로고
    • A phosphoserine/threonine-binding pocket in AGC kinases and PDK 1 mediates activation by hydrophobic motif phosphorylation
    • Frodin M, Antal TL, Dummler BA, Jensen CJ, Deak M, Gammeltoft S, Biondi RM: A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation. EMBO J 21:5396-5407, 2002
    • (2002) EMBO J , vol.21 , pp. 5396-5407
    • Frodin, M.1    Antal, T.L.2    Dummler, B.A.3    Jensen, C.J.4    Deak, M.5    Gammeltoft, S.6    Biondi, R.M.7
  • 20
    • 0031952597 scopus 로고    scopus 로고
    • Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK
    • Dalby KN, Morrice N, Caudwell FB, Avruch J, Cohen P: Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK. J Biol Chem 273:1496-1505, 1998
    • (1998) J Biol Chem , vol.273 , pp. 1496-1505
    • Dalby, K.N.1    Morrice, N.2    Caudwell, F.B.3    Avruch, J.4    Cohen, P.5
  • 21
    • 0027400484 scopus 로고
    • Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2: Identification of two threonines phosphorylated during activation by mitogen-activated protein kinase
    • Sutherland C, Campbell DG, Cohen P: Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2: identification of two threonines phosphorylated during activation by mitogen-activated protein kinase. Eur J Biochem 212:581-588, 1993
    • (1993) Eur J Biochem , vol.212 , pp. 581-588
    • Sutherland, C.1    Campbell, D.G.2    Cohen, P.3
  • 22
    • 0030063435 scopus 로고    scopus 로고
    • Evidence of two catalytical active kinase domains in pp90rsk
    • Fisher TL, Blenis J: Evidence of two catalytical active kinase domains in pp90rsk. Mol Cell Biol 3:1212-1219, 1996
    • (1996) Mol Cell Biol , vol.3 , pp. 1212-1219
    • Fisher, T.L.1    Blenis, J.2
  • 23
    • 0029860520 scopus 로고    scopus 로고
    • Regulation and interaction of pp90(rsk) isoforms with mitogen-activated protein kinases
    • Zhao Y, Bjørbæk C, Moller DE: Regulation and interaction of pp90(rsk) isoforms with mitogen-activated protein kinases. J Biol Chem 271:29773-29779, 1996
    • (1996) J Biol Chem , vol.271 , pp. 29773-29779
    • Zhao, Y.1    Bjørbæk, C.2    Moller, D.E.3
  • 24
    • 0029166989 scopus 로고
    • Divergent functional roles for p90rsk kinase domains
    • Bjørbæk C, Zhao Y, Moller DE: Divergent functional roles for p90rsk kinase domains. J Biol Chem 270:18848-18852, 1995
    • (1995) J Biol Chem , vol.270 , pp. 18848-18852
    • Bjørbæk, C.1    Zhao, Y.2    Moller, D.E.3
  • 25
    • 0027361017 scopus 로고
    • Phosphorylation of the c-fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase
    • Chen RH, Abate C, Blenis J: Phosphorylation of the c-fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase. Proc Natl Acad Sci U S A 90:10952-10956, 1993
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 10952-10956
    • Chen, R.H.1    Abate, C.2    Blenis, J.3
  • 26
    • 0032514734 scopus 로고    scopus 로고
    • Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene
    • De Cesare D, Jacquot S, Hanauer A, Sassone-Corsi P: Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. Proc Natl Acad Sci U S A 95:12202-12207, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 12202-12207
    • De Cesare, D.1    Jacquot, S.2    Hanauer, A.3    Sassone-Corsi, P.4
  • 27
    • 0029789643 scopus 로고    scopus 로고
    • Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
    • Xing J, Ginty DD, Greenberg ME: Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 273:959-963, 1996
    • (1996) Science , vol.273 , pp. 959-963
    • Xing, J.1    Ginty, D.D.2    Greenberg, M.E.3
  • 28
    • 0024240741 scopus 로고
    • Substrate specificity of ribosomal protein S6 kinase II from Xenopus eggs
    • Erikson E, Maller JL: Substrate specificity of ribosomal protein S6 kinase II from Xenopus eggs. Second Messengers Phospoproteins 12:135-143, 1988
    • (1988) Second Messengers Phospoproteins , vol.12 , pp. 135-143
    • Erikson, E.1    Maller, J.L.2
  • 30
    • 0028840004 scopus 로고
    • Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathway in NIH/3T3 cells
    • Eldar-Finkelman H, Seger R, Vandenheede JR, Krebs EG: Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathway in NIH/3T3 cells. J Biol Chem 270:987-990, 1995
    • (1995) J Biol Chem , vol.270 , pp. 987-990
    • Eldar-Finkelman, H.1    Seger, R.2    Vandenheede, J.R.3    Krebs, E.G.4
  • 31
    • 0033520937 scopus 로고    scopus 로고
    • p90(RSK) blocks bad-mediated cell death via protein kinase C-dependent pathway
    • Tan Y, Ruan H, Demeter MR, Comb MJ: p90(RSK) blocks bad-mediated cell death via protein kinase C-dependent pathway. J Biol Chem 274:34859-35867, 1999
    • (1999) J Biol Chem , vol.274 , pp. 34859-35867
    • Tan, Y.1    Ruan, H.2    Demeter, M.R.3    Comb, M.J.4
  • 32
    • 0027233448 scopus 로고
    • Signal transduction via the MAP kinases: Proceed at your own RSK
    • Blenis J: Signal transduction via the MAP kinases: proceed at your own RSK. Proc Natl Acad Sci U S A 90:5889-5892, 1993
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5889-5892
    • Blenis, J.1
  • 33
    • 0036848266 scopus 로고    scopus 로고
    • Expression analysis of RSK gene family members: The RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning
    • Zeniou M, Ding T, Trivier E, Hanauer A: Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum Mol Genet 23:2929-2940, 2002
    • (2002) Hum Mol Genet , vol.23 , pp. 2929-2940
    • Zeniou, M.1    Ding, T.2    Trivier, E.3    Hanauer, A.4
  • 36
    • 0000979928 scopus 로고
    • Mental retardation with osteocartilaginous anomalies
    • Coffin GS, Siris E, Wegienka LC: Mental retardation with osteocartilaginous anomalies. Am J Dis Child 112:205-213, 1966
    • (1966) Am J Dis Child , vol.112 , pp. 205-213
    • Coffin, G.S.1    Siris, E.2    Wegienka, L.C.3
  • 37
    • 0015073716 scopus 로고
    • A new dominant gene mental retardation syndrome
    • Lowry B, Miller JR, Fraser FC: A new dominant gene mental retardation syndrome. Am J Dis Child 121:496-500, 1971
    • (1971) Am J Dis Child , vol.121 , pp. 496-500
    • Lowry, B.1    Miller, J.R.2    Fraser, F.C.3
  • 38
    • 0023945707 scopus 로고
    • The Coffin-Lowry syndrome
    • Young ID: The Coffin-Lowry syndrome. J Med Genet 25:344-348, 1988
    • (1988) J Med Genet , vol.25 , pp. 344-348
    • Young, I.D.1
  • 39
    • 0034747717 scopus 로고    scopus 로고
    • Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice
    • Dufresne SD, Bjørbæk C, El-Haschimi K, Zhao Y, Aschenbach WG, Moller DE, Goodyear LJ: Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice. Mol Cell Biol 21:81-87, 2001
    • (2001) Mol Cell Biol , vol.21 , pp. 81-87
    • Dufresne, S.D.1    Bjørbæk, C.2    El-Haschimi, K.3    Zhao, Y.4    Aschenbach, W.G.5    Moller, D.E.6    Goodyear, L.J.7
  • 40
    • 0022345789 scopus 로고
    • Effect of dietary fat content on the incidence of obesity among ad libitum fed mice
    • Salmon DM, Flatt JP: Effect of dietary fat content on the incidence of obesity among ad libitum fed mice. Int J Obes 9:443-449, 1985
    • (1985) Int J Obes , vol.9 , pp. 443-449
    • Salmon, D.M.1    Flatt, J.P.2
  • 44
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn BB, Flier JS: Obesity and insulin resistance. J Clin Invest 106:473-481, 2000
    • (2000) J Clin Invest , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 46
    • 0033711146 scopus 로고    scopus 로고
    • A-ZIP/F-1 mice lacking white fat: A model for understanding lipoatrophic diabetes
    • Reitman ML, Gavrilova O: A-ZIP/F-1 mice lacking white fat: a model for understanding lipoatrophic diabetes. Int J Obes Retat Metab Disord 24 (Suppl. 4):S11-S14, 2000
    • (2000) Int J Obes Retat Metab Disord , vol.24 , Issue.SUPPL. 4
    • Reitman, M.L.1    Gavrilova, O.2
  • 47
    • 0036328381 scopus 로고    scopus 로고
    • Analysis of paradoxical observations on the association between leptin and insulin
    • Ceddia RB, Koistinen HA, Zierath JR, Sweeney G: Analysis of paradoxical observations on the association between leptin and insulin. FASEB J 10:1163-1176, 2002
    • (2002) FASEB J , vol.10 , pp. 1163-1176
    • Ceddia, R.B.1    Koistinen, H.A.2    Zierath, J.R.3    Sweeney, G.4
  • 48
    • 0032828345 scopus 로고    scopus 로고
    • Decreased visceral adiposity accounts for leptin effect on hepatic but not peripheral insulin action
    • Barzilai N, She L, Liu L, Wang J, Hu M, Vuguin P, Rossetti L: Decreased visceral adiposity accounts for leptin effect on hepatic but not peripheral insulin action. Am J Physiol 277:E291-E298, 1999
    • (1999) Am J Physiol , vol.277
    • Barzilai, N.1    She, L.2    Liu, L.3    Wang, J.4    Hu, M.5    Vuguin, P.6    Rossetti, L.7
  • 49
    • 0032948427 scopus 로고    scopus 로고
    • Chronic leptin administration increases insulin-stimulated skeletal muscle glucose uptake and transport
    • Yaspelkis BB 3rd, Ansari L, Ramey EL, Holland GJ, Loy SF: Chronic leptin administration increases insulin-stimulated skeletal muscle glucose uptake and transport. Metabolism 48:671-676, 1999
    • (1999) Metabolism , vol.48 , pp. 671-676
    • Yaspelkis B.B. III1    Ansari, L.2    Ramey, E.L.3    Holland, G.J.4    Loy, S.F.5
  • 50
  • 51
    • 0034901465 scopus 로고    scopus 로고
    • Disease model: Hyperinsulinemia and insulin resistance. Part B: Polygenic and other animal models
    • Sone H, Takahashi A, Iida K, Yamada N: Disease model: hyperinsulinemia and insulin resistance. Part B: polygenic and other animal models. Trends Mol Med 8:373-376, 2001
    • (2001) Trends Mol Med , vol.8 , pp. 373-376
    • Sone, H.1    Takahashi, A.2    Iida, K.3    Yamada, N.4
  • 52
    • 0035195121 scopus 로고    scopus 로고
    • Leptin and its relation to obesity and insulin in the SHR/N-corpulent rat, a model of type II diabetes mellitus
    • Velasque MT, Bhathena SJ, Hansen CT: Leptin and its relation to obesity and insulin in the SHR/N-corpulent rat, a model of type II diabetes mellitus. Int J Exp Diabetes Res 2:217-223, 2001
    • (2001) Int J Exp Diabetes Res , vol.2 , pp. 217-223
    • Velasque, M.T.1    Bhathena, S.J.2    Hansen, C.T.3
  • 53
    • 0033517284 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    • Shimomura I, Hammer RE, Ikemoto S, Brown MS, Goldstein JL: Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 401:73-76, 1999
    • (1999) Nature , vol.401 , pp. 73-76
    • Shimomura, I.1    Hammer, R.E.2    Ikemoto, S.3    Brown, M.S.4    Goldstein, J.L.5
  • 54
    • 0029560493 scopus 로고
    • Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice: Implications for the regulation of glycogen synthase
    • Chang PY, Le Marchand-Brustel Y, Cheatham LA, Moller DE: Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice: implications for the regulation of glycogen synthase. J Biol Chem 270:29928-29935, 1995
    • (1995) J Biol Chem , vol.270 , pp. 29928-29935
    • Chang, P.Y.1    Le Marchand-Brustel, Y.2    Cheatham, L.A.3    Moller, D.E.4
  • 55
    • 0025522071 scopus 로고
    • The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
    • Dent P, Lavoinne A, Nakielny S, Caudwell FB, Watt P, Cohen P: The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle. Nature 348:302-308, 1990
    • (1990) Nature , vol.348 , pp. 302-308
    • Dent, P.1    Lavoinne, A.2    Nakielny, S.3    Caudwell, F.B.4    Watt, P.5    Cohen, P.6
  • 56
    • 0034711239 scopus 로고    scopus 로고
    • Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD
    • Bertolotto C, Maulon L, Filippa N, Baier G, Auberger P: Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD. J Biol Chem 275:37246-37250, 2000
    • (2000) J Biol Chem , vol.275 , pp. 37246-37250
    • Bertolotto, C.1    Maulon, L.2    Filippa, N.3    Baier, G.4    Auberger, P.5
  • 57
    • 0037025296 scopus 로고    scopus 로고
    • Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of BAD by ultraviolet B radiation
    • She QB, Ma WY, Zhong S, Dong Z: Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of BAD by ultraviolet B radiation. J Biol Chem 277:24039-24048, 2002
    • (2002) J Biol Chem , vol.277 , pp. 24039-24048
    • She, Q.B.1    Ma, W.Y.2    Zhong, S.3    Dong, Z.4
  • 59
    • 0036750241 scopus 로고    scopus 로고
    • Adiponectin: Its role in metabolism and beyond
    • Stefan N, Stumvoll M: Adiponectin: its role in metabolism and beyond. Horm Metab Res 34:469-474, 2002
    • (2002) Horm Metab Res , vol.34 , pp. 469-474
    • Stefan, N.1    Stumvoll, M.2
  • 60
    • 0036034966 scopus 로고    scopus 로고
    • Identification of regulatory elements in human adipose most abundant gene transcript-1 (apM-1) promoter: Role of SP1/SP3 and TNF-alpha as regulatory pathways
    • Barth N, Langmann T, Scholmerich J, Schmitz G, Schaffler A: Identification of regulatory elements in human adipose most abundant gene transcript-1 (apM-1) promoter: role of SP1/SP3 and TNF-alpha as regulatory pathways. Diabetologia 45:1425-1433, 2002
    • (2002) Diabetologia , vol.45 , pp. 1425-1433
    • Barth, N.1    Langmann, T.2    Scholmerich, J.3    Schmitz, G.4    Schaffler, A.5
  • 61
    • 0036616582 scopus 로고    scopus 로고
    • Identifying the links between obesity, insulin resistance and beta-cell function: Potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes
    • Greenberg AS, McDaniel ML: Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes. Eur J Clin Invest 32:24-34, 2002
    • (2002) Eur J Clin Invest , vol.32 , pp. 24-34
    • Greenberg, A.S.1    McDaniel, M.L.2


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