Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 3, 2005, Pages 667-672

  Ballif, Bryan A ^a   Roux, Philippe P ^a   Gerber, Scott A ^a   MacKeigan, Jeffrey P ^a   Blenis, John ^a   Gygi, Steven P ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Extracellular signal regulated kinase; Quantitative mass spectrometry; Signal transduction; Stable isotope labeling

Indexed keywords

BISINDOLYLMALEIMIDE; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN TSC1; S6 KINASE; STABLE ISOTOPE; TUBERIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOLYSIS; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY;

BINDING SITES; CELL LINE; EPIDERMAL GROWTH FACTOR; HUMANS; MAP KINASE SIGNALING SYSTEM; MASS SPECTROMETRY; PHORBOL ESTERS; PHOSPHORUS ISOTOPES; PHOSPHORYLATION; PROTEIN KINASE C; REPRESSOR PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 14144254701     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409143102     Document Type: Article

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