-
1
-
-
0023084725
-
Apoptosis: Cell death under homeostatic control
-
Wyllie AH. Apoptosis: cell death under homeostatic control. Arch Toxicol Suppl 1987; 11: 3-10.
-
(1987)
Arch Toxicol Suppl
, vol.11
, pp. 3-10
-
-
Wyllie, A.H.1
-
2
-
-
0034641963
-
Defying death after DNA damage
-
Rich T, Allen RL, Wyllie AH. Defying death after DNA damage. Nature 2000; 407: 777-783.
-
(2000)
Nature
, vol.407
, pp. 777-783
-
-
Rich, T.1
Allen, R.L.2
Wyllie, A.H.3
-
3
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
0036204110
-
The regulation of APAF1 expression during development and tumourigenesis
-
Hickman ES, Helin K. The regulation of APAF1 expression during development and tumourigenesis. Apoptosis 2002; 7: 167-171.
-
(2002)
Apoptosis
, vol.7
, pp. 167-171
-
-
Hickman, E.S.1
Helin, K.2
-
5
-
-
0032796715
-
Apoptosis and carcinogenesis
-
Wyllie AH et al. Apoptosis and carcinogenesis. Br J Cancer 1999; 80 Suppl 1: 34-37.
-
(1999)
Br J Cancer
, vol.80
, Issue.SUPPL. 1
, pp. 34-37
-
-
Wyllie, A.H.1
-
6
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed JC. Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999; 11: 68-75.
-
(1999)
Curr Opin Oncol
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
7
-
-
0034905394
-
XIAP: Apoptotic brake and promising therapeutic target
-
Holcik M, Gibson H, Korneluk RG. XIAP: apoptotic brake and promising therapeutic target. Apoptosis 2001; 6: 253-261.
-
(2001)
Apoptosis
, vol.6
, pp. 253-261
-
-
Holcik, M.1
Gibson, H.2
Korneluk, R.G.3
-
8
-
-
0036547417
-
Death and anti-death: Tumour resistance to apoptosis
-
Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002; 2: 277-288.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
9
-
-
0037233327
-
Survivin and apoptosis control
-
Altieri DC. Survivin and apoptosis control. Adv Cancer Res 2003; 88: 31-52.
-
(2003)
Adv Cancer Res
, vol.88
, pp. 31-52
-
-
Altieri, D.C.1
-
12
-
-
0037020196
-
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
-
Debnath J et al. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell 2002; 111: 29-40.
-
(2002)
Cell
, vol.111
, pp. 29-40
-
-
Debnath, J.1
-
13
-
-
0031720975
-
Apoptosis in the mammary gland and breast cancer
-
Hahm HaD, NE. Apoptosis in the mammary gland and breast cancer. Endocrine-Related Cancer 1998; 5: 199-211.
-
(1998)
Endocrine-Related Cancer
, vol.5
, pp. 199-211
-
-
Hahm, D.1
Ha, N.E.2
-
14
-
-
0029056951
-
Potential roles of apoptosis in viral pathogenesis
-
Collins M. Potential roles of apoptosis in viral pathogenesis. Am J Respir Crit Care Med 1995; 152: S20-24.
-
(1995)
Am J Respir Crit Care Med
, vol.152
-
-
Collins, M.1
-
15
-
-
0030790430
-
Cell death in the regulation of immune responses
-
Winoto A. Cell death in the regulation of immune responses. Curr Opin Immunol 1997; 9: 365-370.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 365-370
-
-
Winoto, A.1
-
16
-
-
0033873788
-
UV-induced apoptosis in resistant HeLa cells
-
Kamarajan P, Chao CC. UV-induced apoptosis in resistant HeLa cells. Biosci Rep 2000; 20: 99-108.
-
(2000)
Biosci Rep
, vol.20
, pp. 99-108
-
-
Kamarajan, P.1
Chao, C.C.2
-
17
-
-
0642375738
-
Ionizing radiation and nitric oxide donor sensitize Fas-induced apoptosis via up-regulation of Fas in human cervical cancer cells
-
Park IC et al. Ionizing radiation and nitric oxide donor sensitize Fas-induced apoptosis via up-regulation of Fas in human cervical cancer cells. Oncol Rep 2003; 10: 629-633.
-
(2003)
Oncol Rep
, vol.10
, pp. 629-633
-
-
Park, I.C.1
-
18
-
-
0034630167
-
Induction of apoptosis by cancer chemotherapy
-
Kaufmann SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res 2000; 256: 42-49.
-
(2000)
Exp Cell Res
, vol.256
, pp. 42-49
-
-
Kaufmann, S.H.1
Earnshaw, W.C.2
-
19
-
-
0034320568
-
Mechanisms of apoptosis
-
Reed JC. Mechanisms of apoptosis. Am J Pathol 2000; 157: 1415-1430.
-
(2000)
Am J Pathol
, vol.157
, pp. 1415-1430
-
-
Reed, J.C.1
-
20
-
-
0032910361
-
Mitochondrial regulation of cell death: Mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death
-
Suzuki A et al. Mitochondrial regulation of cell death: mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death. Mol Cell Biol 1999; 19: 3842-3847.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3842-3847
-
-
Suzuki, A.1
-
21
-
-
2442460088
-
Role of mitochondrial membrane permeabilization in apoptosis and cancer
-
Henry-Mowatt J, Dive C, Martinou JC, James D. Role of mitochondrial membrane permeabilization in apoptosis and cancer. Oncogene 2004; 23: 2850-2860.
-
(2004)
Oncogene
, vol.23
, pp. 2850-2860
-
-
Henry-Mowatt, J.1
Dive, C.2
Martinou, J.C.3
James, D.4
-
22
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo I et al. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 1999; 15: 269-290.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
-
23
-
-
0032416062
-
Death by a thousand cuts: An ever increasing list of caspase substrates
-
Stroh C, Schulze-Osthoff K. Death by a thousand cuts: an ever increasing list of caspase substrates. Cell Death Differ 1998; 5: 997-1000.
-
(1998)
Cell Death Differ
, vol.5
, pp. 997-1000
-
-
Stroh, C.1
Schulze-Osthoff, K.2
-
25
-
-
4143108125
-
CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells
-
Barnhart BC et al. CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. Embo J 2004; 23: 3175-3185.
-
(2004)
Embo J
, vol.23
, pp. 3175-3185
-
-
Barnhart, B.C.1
-
26
-
-
0034856368
-
CD95 antigen mutations in hematopoietic malignancies
-
Landowski TH et al. CD95 antigen mutations in hematopoietic malignancies. Leuk Lymphoma 2001; 42: 835-846.
-
(2001)
Leuk Lymphoma
, vol.42
, pp. 835-846
-
-
Landowski, T.H.1
-
27
-
-
0032525198
-
CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia
-
Beltinger C et al. CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia. Blood 1998; 91: 3943-3951.
-
(1998)
Blood
, vol.91
, pp. 3943-3951
-
-
Beltinger, C.1
-
28
-
-
0033600179
-
Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer
-
Lee SH et al. Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer. Oncogene 1999; 18: 3754-3760.
-
(1999)
Oncogene
, vol.18
, pp. 3754-3760
-
-
Lee, S.H.1
-
29
-
-
0036133858
-
Identification of Fas (APO-1/CD95) and p53 gene mutations in non-small cell lung cancer
-
Boldrini L et al. Identification of Fas (APO-1/CD95) and p53 gene mutations in non-small cell lung cancer. Int J Oncol 2002; 20: 155-159.
-
(2002)
Int J Oncol
, vol.20
, pp. 155-159
-
-
Boldrini, L.1
-
30
-
-
0035999095
-
Frequent downregulation of Fas (CD95) expression and function in melanoma
-
Bullani RR et al. Frequent downregulation of Fas (CD95) expression and function in melanoma. Melanoma Res 2002; 12: 263-270.
-
(2002)
Melanoma Res
, vol.12
, pp. 263-270
-
-
Bullani, R.R.1
-
31
-
-
0035079863
-
Expression of Fas and Fas-related molecules in human hepatocellular carcinoma
-
Lee SH et al. Expression of Fas and Fas-related molecules in human hepatocellular carcinoma. Hum Pathol 2001; 32: 250-256.
-
(2001)
Hum Pathol
, vol.32
, pp. 250-256
-
-
Lee, S.H.1
-
32
-
-
0032032577
-
Lack of cell surface Fas/APO-1 expression in pulmonary adenocarcinomas
-
Nambu Y et al. Lack of cell surface Fas/APO-1 expression in pulmonary adenocarcinomas. J Clin Invest 1998; 101: 1102-1110.
-
(1998)
J Clin Invest
, vol.101
, pp. 1102-1110
-
-
Nambu, Y.1
-
33
-
-
0141926700
-
Frequent loss of Fas expression and function in human lung tumours with overexpression of FasL in small cell lung carcinoma
-
Viard-Leveugle I et al. Frequent loss of Fas expression and function in human lung tumours with overexpression of FasL in small cell lung carcinoma. J Pathol 2003; 201: 268-277.
-
(2003)
J Pathol
, vol.201
, pp. 268-277
-
-
Viard-Leveugle, I.1
-
34
-
-
0033054108
-
In vivo expression of soluble Fas and FAP-1: Possible mechanisms of Fas resistance in human hepatoblastomas
-
Lee SH et al. In vivo expression of soluble Fas and FAP-1: possible mechanisms of Fas resistance in human hepatoblastomas. J Pathol 1999; 188: 207-212.
-
(1999)
J Pathol
, vol.188
, pp. 207-212
-
-
Lee, S.H.1
-
35
-
-
0037103302
-
Blockade of Fas-dependent apoptosis by soluble Fas in LGL leukemia
-
Liu JH et al. Blockade of Fas-dependent apoptosis by soluble Fas in LGL leukemia. Blood 2002; 100: 1449-1453.
-
(2002)
Blood
, vol.100
, pp. 1449-1453
-
-
Liu, J.H.1
-
36
-
-
0035258678
-
Human pancreatic cancer cells disable function of Fas receptors at several levels in Fas signal transduction pathway
-
Elnemr A et al. Human pancreatic cancer cells disable function of Fas receptors at several levels in Fas signal transduction pathway. Int J Oncol 2001; 18: 311-316.
-
(2001)
Int J Oncol
, vol.18
, pp. 311-316
-
-
Elnemr, A.1
-
37
-
-
19244376868
-
Resistance to CD95 (APO-1/Fas)-mediated apoptosis in human renal cell carcinomas: An important factor for evasion from negative growth control
-
Gerharz CD et al. Resistance to CD95 (APO-1/Fas)-mediated apoptosis in human renal cell carcinomas: an important factor for evasion from negative growth control. Lab Invest 1999; 79: 1521-1534.
-
(1999)
Lab Invest
, vol.79
, pp. 1521-1534
-
-
Gerharz, C.D.1
-
38
-
-
0035871978
-
Resistance to CD95-mediated apoptosis in breast cancer is not due to somatic mutation of the CD95 gene
-
Muschen M et al. Resistance to CD95-mediated apoptosis in breast cancer is not due to somatic mutation of the CD95 gene. Int J Cancer 2001; 92: 309-310.
-
(2001)
Int J Cancer
, vol.92
, pp. 309-310
-
-
Muschen, M.1
-
39
-
-
0029817663
-
Fas expression and function in normal and malignant breast cell lines
-
Keane MM et al. Fas expression and function in normal and malignant breast cell lines. Cancer Res 1996; 56: 4791-4798.
-
(1996)
Cancer Res
, vol.56
, pp. 4791-4798
-
-
Keane, M.M.1
-
40
-
-
0032522848
-
Human pancreatic adenocarcinomas express Fas and Fas ligand yet are resistant to Fas-mediated apoptosis
-
Ungefroren H et al. Human pancreatic adenocarcinomas express Fas and Fas ligand yet are resistant to Fas-mediated apoptosis. Cancer Res 1998; 58: 1741-1749.
-
(1998)
Cancer Res
, vol.58
, pp. 1741-1749
-
-
Ungefroren, H.1
-
41
-
-
0027145632
-
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
-
Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993; 75: 1169-1178.
-
(1993)
Cell
, vol.75
, pp. 1169-1178
-
-
Suda, T.1
Takahashi, T.2
Golstein, P.3
Nagata, S.4
-
42
-
-
0028864778
-
A role for CD95 ligand in preventing graft rejection
-
Bellgrau D et al. A role for CD95 ligand in preventing graft rejection. Nature 1995; 377: 630-632.
-
(1995)
Nature
, vol.377
, pp. 630-632
-
-
Bellgrau, D.1
-
43
-
-
0342979787
-
Fas ligand is expressed in normal breast epithelial cells and is frequently up-regulated in breast cancer
-
Mullauer L et al. Fas ligand is expressed in normal breast epithelial cells and is frequently up-regulated in breast cancer. J Pathol 2000; 190: 20-30.
-
(2000)
J Pathol
, vol.190
, pp. 20-30
-
-
Mullauer, L.1
-
44
-
-
0041411313
-
The Fas/Fas ligand system and cancer: Immune privilege and apoptosis
-
Abrahams VM, Kamsteeg M, Mor G. The Fas/Fas ligand system and cancer: immune privilege and apoptosis. Mol Biotechnol 2003; 25: 19-30.
-
(2003)
Mol Biotechnol
, vol.25
, pp. 19-30
-
-
Abrahams, V.M.1
Kamsteeg, M.2
Mor, G.3
-
45
-
-
0034881170
-
Fas ligand upregulation is an early event in colonic carcinogenesis
-
Bennett MW et al. Fas ligand upregulation is an early event in colonic carcinogenesis. J Clin Pathol 2001; 54: 598-604.
-
(2001)
J Clin Pathol
, vol.54
, pp. 598-604
-
-
Bennett, M.W.1
-
46
-
-
0034036052
-
Expression of the apoptosis-inducing ligands FasL and TRAIL in malignant and benign human breast tumors
-
Herrnring C et al. Expression of the apoptosis-inducing ligands FasL and TRAIL in malignant and benign human breast tumors. Histochem Cell Biol 2000; 113: 189-194.
-
(2000)
Histochem Cell Biol
, vol.113
, pp. 189-194
-
-
Herrnring, C.1
-
47
-
-
0242584489
-
Prognostic relevance of Fas (APO-1/CD95) ligand in human colorectal cancer
-
Sheehan KM et al. Prognostic relevance of Fas (APO-1/CD95) ligand in human colorectal cancer. Eur J Gastroenterol Hepatol 2003; 15: 375-380.
-
(2003)
Eur J Gastroenterol Hepatol
, vol.15
, pp. 375-380
-
-
Sheehan, K.M.1
-
48
-
-
0001646169
-
Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation
-
Boesen-de Cock JG et al. Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation. J Biol Chem 1999; 274: 14255-14261.
-
(1999)
J Biol Chem
, vol.274
, pp. 14255-14261
-
-
Boesen-De Cock, J.G.1
-
49
-
-
0030752603
-
The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells
-
Fulda S et al. The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells. Cancer Res 1997; 57: 3823-3829.
-
(1997)
Cancer Res
, vol.57
, pp. 3823-3829
-
-
Fulda, S.1
-
50
-
-
0030897001
-
Selection for drug resistance results in resistance to Fas-mediated apoptosis
-
Landowski TH, Gleason-Guzman MC, Dalton WS. Selection for drug resistance results in resistance to Fas-mediated apoptosis. Blood 1997; 89: 1854-1861.
-
(1997)
Blood
, vol.89
, pp. 1854-1861
-
-
Landowski, T.H.1
Gleason-Guzman, M.C.2
Dalton, W.S.3
-
51
-
-
0346792725
-
TRAIL and apoptosis induction by TNF-family death receptors
-
Wang S, El-Deiry WS. TRAIL and apoptosis induction by TNF-family death receptors. Oncogene 2003; 22: 8628-8633.
-
(2003)
Oncogene
, vol.22
, pp. 8628-8633
-
-
Wang, S.1
El-Deiry, W.S.2
-
52
-
-
3342894130
-
Targeting death receptors in cancer with Apo2L/TRAIL
-
Kelley SK, Ashkenazi A. Targeting death receptors in cancer with Apo2L/TRAIL. Curr Opin Pharmacol 2004; 4: 333-339.
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 333-339
-
-
Kelley, S.K.1
Ashkenazi, A.2
-
53
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
LeBlanc HN, Ashkenazi A. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 2003; 10: 66-75.
-
(2003)
Cell Death Differ
, vol.10
, pp. 66-75
-
-
Leblanc, H.N.1
Ashkenazi, A.2
-
55
-
-
0032910169
-
Apoptosis control by death and decoy receptors
-
Ashkenazi A, Dixit VM. Apoptosis control by death and decoy receptors. Curr Opin Cell Biol 1999; 11: 255-260.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 255-260
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
56
-
-
0034956807
-
Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death
-
Ibrahim SM et al. Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death. Pancreas 2001; 23: 72-79.
-
(2001)
Pancreas
, vol.23
, pp. 72-79
-
-
Ibrahim, S.M.1
-
57
-
-
0141705424
-
Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo
-
Singh TR et al. Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo. Cancer Res 2003; 63: 5390-5400.
-
(2003)
Cancer Res
, vol.63
, pp. 5390-5400
-
-
Singh, T.R.1
-
58
-
-
9944263245
-
Deficient TRAIL death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis
-
Jin Z, McDonald ER, 3rd, Dicker DT, El-Deiry WS. Deficient TRAIL death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis. J Biol Chem 2004.
-
(2004)
J Biol Chem
-
-
Jin, Z.1
McDonald, E.R.2
Dicker III, D.T.3
El-Deiry, W.S.4
-
59
-
-
0036466842
-
TRAIL, FasL and a blocking anti-DR5 antibody augment paclitaxel-induced apoptosis in human non-small-cell lung cancer
-
Odoux C et al. TRAIL, FasL and a blocking anti-DR5 antibody augment paclitaxel-induced apoptosis in human non-small-cell lung cancer. Int J Cancer 2002; 97: 458-465.
-
(2002)
Int J Cancer
, vol.97
, pp. 458-465
-
-
Odoux, C.1
-
60
-
-
2942565827
-
Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: Mechanisms and clinical implications
-
Shankar S, Srivastava RK. Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications. Drug Resist Updat 2004; 7: 139-156.
-
(2004)
Drug Resist Updat
, vol.7
, pp. 139-156
-
-
Shankar, S.1
Srivastava, R.K.2
-
61
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998; 281: 1305-1308.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
62
-
-
0037054549
-
Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms
-
Morgan M, Thorburn J, Pandolfi PP, Thorburn A. Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms. J Cell Biol 2002; 157: 975-984.
-
(2002)
J Cell Biol
, vol.157
, pp. 975-984
-
-
Morgan, M.1
Thorburn, J.2
Pandolfi, P.P.3
Thorburn, A.4
-
63
-
-
1342285692
-
Tumor necrosis factor: An apoptosis JuNKie?
-
Varfolomeev EE, Ashkenazi A. Tumor necrosis factor: an apoptosis JuNKie? Cell 2004; 116: 491-497.
-
(2004)
Cell
, vol.116
, pp. 491-497
-
-
Varfolomeev, E.E.1
Ashkenazi, A.2
-
64
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
Micheau O et al. NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol 2001; 21: 5299-5305.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5299-5305
-
-
Micheau, O.1
-
65
-
-
0034983077
-
Expression of the tumour necrosis factor receptor-associated factors 1 and 2 in Hodgkin's disease
-
Murray PG et al. Expression of the tumour necrosis factor receptor-associated factors 1 and 2 in Hodgkin's disease. J Pathol 2001; 194: 158-164.
-
(2001)
J Pathol
, vol.194
, pp. 158-164
-
-
Murray, P.G.1
-
66
-
-
0034326624
-
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
-
Zapata JM et al. TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. J Immunol 2000; 165: 5084-5096.
-
(2000)
J Immunol
, vol.165
, pp. 5084-5096
-
-
Zapata, J.M.1
-
67
-
-
0037621450
-
Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation
-
Hopkins-Donaldson S et al. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ 2003; 10: 356-364.
-
(2003)
Cell Death Differ
, vol.10
, pp. 356-364
-
-
Hopkins-Donaldson, S.1
-
68
-
-
0141453653
-
Caspase 3 and 8 deficiency in human neuroblastoma
-
Iolascon A et al. Caspase 3 and 8 deficiency in human neuroblastoma. Cancer Genet Cytogenet 2003; 146: 41-47.
-
(2003)
Cancer Genet Cytogenet
, vol.146
, pp. 41-47
-
-
Iolascon, A.1
-
69
-
-
0034066405
-
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
-
Teitz T et al. Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 2000; 6: 529-535.
-
(2000)
Nat Med
, vol.6
, pp. 529-535
-
-
Teitz, T.1
-
70
-
-
0033890808
-
Reduced expression of ICE/caspase1 and CPP32/caspase3 in human hepatocellular carcinoma
-
Fujikawa K et al. Reduced expression of ICE/caspase1 and CPP32/caspase3 in human hepatocellular carcinoma. Anticancer Res 2000; 20: 1927-1932.
-
(2000)
Anticancer Res
, vol.20
, pp. 1927-1932
-
-
Fujikawa, K.1
-
71
-
-
0033564103
-
Dead or dying: Necrosis versus apoptosis in caspase-deficient human renal cell carcinoma
-
Kolenko V et al. Dead or dying: necrosis versus apoptosis in caspase-deficient human renal cell carcinoma. Cancer Res 1999; 59: 2838-2842.
-
(1999)
Cancer Res
, vol.59
, pp. 2838-2842
-
-
Kolenko, V.1
-
72
-
-
0034990676
-
Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma
-
Palmerini F et al. Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma. Hum Pathol 2001; 32: 461-467.
-
(2001)
Hum Pathol
, vol.32
, pp. 461-467
-
-
Palmerini, F.1
-
73
-
-
0035937797
-
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
-
Chu ZL et al. A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J Biol Chem 2001; 276: 9239-9245.
-
(2001)
J Biol Chem
, vol.276
, pp. 9239-9245
-
-
Chu, Z.L.1
-
74
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas MS et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 2001; 409: 207-211.
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
-
75
-
-
0035744678
-
Immunohistochemical expression of caspase-3 as an adverse indicator of the clinical outcome in human breast cancer
-
Nakopoulou L et al. Immunohistochemical expression of caspase-3 as an adverse indicator of the clinical outcome in human breast cancer. Pathobiology 2001; 69: 266-273.
-
(2001)
Pathobiology
, vol.69
, pp. 266-273
-
-
Nakopoulou, L.1
-
76
-
-
0032881750
-
Expression of caspases 3, 6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion
-
Vakkala M, Paakko P, Soini Y. Expression of caspases 3, 6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion. Br J Cancer 1999; 81: 592-599.
-
(1999)
Br J Cancer
, vol.81
, pp. 592-599
-
-
Vakkala, M.1
Paakko, P.2
Soini, Y.3
-
77
-
-
0035992283
-
Coordinate expression of apoptosis-associated proteins in human breast cancer before and during chemotherapy
-
Parton M et al. Coordinate Expression of Apoptosis-associated Proteins in Human Breast Cancer before and during Chemotherapy. Clin Cancer Res 2002; 8: 2100-2108.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2100-2108
-
-
Parton, M.1
-
78
-
-
0037312545
-
Caspase 3 in breast cancer
-
O'Donovan N et al. Caspase 3 in breast cancer. Clin Cancer Res 2003; 9: 738-742.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 738-742
-
-
O'Donovan, N.1
-
79
-
-
0142188706
-
Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: Implication for cancer specific therapy
-
Yang L, Cao Z, Yan H, Wood WC. Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. Cancer Res 2003; 63: 6815-6824.
-
(2003)
Cancer Res
, vol.63
, pp. 6815-6824
-
-
Yang, L.1
Cao, Z.2
Yan, H.3
Wood, W.C.4
-
80
-
-
0035878930
-
Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors
-
Satoh K et al. Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors. Cancer 2001; 92: 271-278.
-
(2001)
Cancer
, vol.92
, pp. 271-278
-
-
Satoh, K.1
-
81
-
-
0036876248
-
Stomach cancer highly expresses both initiator and effector caspases; An immunohistochemical study
-
Yoo NJ et al. Stomach cancer highly expresses both initiator and effector caspases; an immunohistochemical study. Apmis 2002; 110: 825-832.
-
(2002)
Apmis
, vol.110
, pp. 825-832
-
-
Yoo, N.J.1
-
82
-
-
0033386808
-
Caspase activation is required for T cell proliferation
-
Kennedy NJ, Kataoka T, Tschopp J, Budd RC. Caspase activation is required for T cell proliferation. J Exp Med 1999; 190: 1891-1896.
-
(1999)
J Exp Med
, vol.190
, pp. 1891-1896
-
-
Kennedy, N.J.1
Kataoka, T.2
Tschopp, J.3
Budd, R.C.4
-
83
-
-
0036824646
-
Differential modulation of interleukin-2-and interleukin-4-mediated early activation of normal human B lymphocytes by the caspase inhibitor zVAD-fmk
-
Mouhamad S et al. Differential modulation of interleukin-2-and interleukin-4-mediated early activation of normal human B lymphocytes by the caspase inhibitor zVAD-fmk. Eur Cytokine Netw 2002; 13: 439-445.
-
(2002)
Eur Cytokine Netw
, vol.13
, pp. 439-445
-
-
Mouhamad, S.1
-
84
-
-
0036446885
-
Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner
-
Rendl M et al. Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner. J Invest Dermatol 2002; 119: 1150-1155.
-
(2002)
J Invest Dermatol
, vol.119
, pp. 1150-1155
-
-
Rendl, M.1
-
85
-
-
0036377840
-
The biological role of the Fas/FasL system during tumor formation and progression
-
Reichmann E. The biological role of the Fas/FasL system during tumor formation and progression. Semin Cancer Biol 2002; 12: 309-315.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 309-315
-
-
Reichmann, E.1
-
87
-
-
4844220794
-
Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro
-
Abedini MR, Qiu Q, Yan X, Tsang BK. Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro. Oncogene 2004.
-
(2004)
Oncogene
-
-
Abedini, M.R.1
Qiu, Q.2
Yan, X.3
Tsang, B.K.4
-
88
-
-
0038556793
-
Increased expression of FLIP, an inhibitor of Fas-mediated apoptosis, in stomach cancer
-
Lee SH et al. Increased expression of FLIP, an inhibitor of Fas-mediated apoptosis, in stomach cancer. Apmis 2003; 111: 309-314.
-
(2003)
Apmis
, vol.111
, pp. 309-314
-
-
Lee, S.H.1
-
89
-
-
0032530612
-
Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
-
Griffith TS et al. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J Immunol 1998; 161: 2833-2840.
-
(1998)
J Immunol
, vol.161
, pp. 2833-2840
-
-
Griffith, T.S.1
-
90
-
-
0344393606
-
Up-regulation of FLIP in cisplatin-selected HeLa cells causes cross-resistance to CD95/Fas death signalling
-
Kamarajan P, Sun NK, Chao CC. Up-regulation of FLIP in cisplatin-selected HeLa cells causes cross-resistance to CD95/Fas death signalling. Biochem J 2003; 376: 253-260.
-
(2003)
Biochem J
, vol.376
, pp. 253-260
-
-
Kamarajan, P.1
Sun, N.K.2
Chao, C.C.3
-
91
-
-
0032409781
-
Bcl-2 family proteins
-
Reed JC. Bcl-2 family proteins. Oncogene 1998; 17: 3225-3236.
-
(1998)
Oncogene
, vol.17
, pp. 3225-3236
-
-
Reed, J.C.1
-
92
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22: 8590-8607.
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
93
-
-
0028958030
-
Bcl-2: Prevention of apoptosis as a mechanism of drug resistance
-
Reed JC. Bcl-2: prevention of apoptosis as a mechanism of drug resistance. Hematol Oncol Clin North Am 1995; 9: 451-473.
-
(1995)
Hematol Oncol Clin North Am
, vol.9
, pp. 451-473
-
-
Reed, J.C.1
-
94
-
-
0027970798
-
Immunocytochemical localization of BCL-2 protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy
-
Gee JM et al. Immunocytochemical localization of BCL-2 protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy. Int J Cancer 1994; 59: 619-628.
-
(1994)
Int J Cancer
, vol.59
, pp. 619-628
-
-
Gee, J.M.1
-
95
-
-
0029794419
-
Upregulated expression of BCL-2 in multiple myeloma cells induced by exposure to doxorubicin, etoposide, and hydrogen peroxide
-
Tu Y et al. Upregulated expression of BCL-2 in multiple myeloma cells induced by exposure to doxorubicin, etoposide, and hydrogen peroxide. Blood 1996; 88: 1805-1812.
-
(1996)
Blood
, vol.88
, pp. 1805-1812
-
-
Tu, Y.1
-
96
-
-
0037018277
-
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression
-
Fulda S, Meyer E, Debatin KM. Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression. Oncogene 2002; 21: 2283-2294.
-
(2002)
Oncogene
, vol.21
, pp. 2283-2294
-
-
Fulda, S.1
Meyer, E.2
Debatin, K.M.3
-
97
-
-
0242721548
-
Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists
-
Wang S, Yang D, Lippman ME. Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists. Semin Oncol 2003; 30: 133-142.
-
(2003)
Semin Oncol
, vol.30
, pp. 133-142
-
-
Wang, S.1
Yang, D.2
Lippman, M.E.3
-
98
-
-
0031575073
-
Promise and problems of Bcl-2 antisense therapy
-
Reed JC. Promise and problems of Bcl-2 antisense therapy. J Natl Cancer Inst 1997; 89: 988-990.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 988-990
-
-
Reed, J.C.1
-
99
-
-
0036463649
-
Apoptosis-based therapies
-
Reed JC. Apoptosis-based therapies. Nat Rev Drug Discov 2002; 1: 111-121.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 111-121
-
-
Reed, J.C.1
-
100
-
-
0032943691
-
Prognostic significance of apoptosis regulators in breast cancer
-
Krajewski S et al. Prognostic significance of apoptosis regulators in breast cancer. Endocr Relat Cancer 1999; 6: 29-40.
-
(1999)
Endocr Relat Cancer
, vol.6
, pp. 29-40
-
-
Krajewski, S.1
-
101
-
-
0033973291
-
Immunohistochemical analysis of Bcl-2 and Bax expression in relation to cell turnover and epithelial differentiation markers in the non-lactating human mammary gland epithelium
-
Feuerhake F et al. Immunohistochemical analysis of Bcl-2 and Bax expression in relation to cell turnover and epithelial differentiation markers in the non-lactating human mammary gland epithelium. Cell Tissue Res 2000; 299: 47-58.
-
(2000)
Cell Tissue Res
, vol.299
, pp. 47-58
-
-
Feuerhake, F.1
-
102
-
-
0027944957
-
Bcl-2 protein expression and long-term survival in breast cancer
-
Joensuu H, Pylkkanen L, Toikkanen S. Bcl-2 protein expression and long-term survival in breast cancer. Am J Pathol 1994; 145: 1191-1198.
-
(1994)
Am J Pathol
, vol.145
, pp. 1191-1198
-
-
Joensuu, H.1
Pylkkanen, L.2
Toikkanen, S.3
-
103
-
-
0031927561
-
Apoptotic index correlates to bcl-2 and p53 protein expression, histological grade and prognosis in invasive breast cancers
-
Zhang GJ et al. Apoptotic index correlates to bcl-2 and p53 protein expression, histological grade and prognosis in invasive breast cancers. Anticancer Res 1998; 18: 1989-1998.
-
(1998)
Anticancer Res
, vol.18
, pp. 1989-1998
-
-
Zhang, G.J.1
-
104
-
-
0035080860
-
Bcl-2 Expression and apoptosis in primary and metastatic breast carcinomas
-
Villar E et al. bcl-2 Expression and apoptosis in primary and metastatic breast carcinomas. Tumour Biol 2001; 22: 137-145.
-
(2001)
Tumour Biol
, vol.22
, pp. 137-145
-
-
Villar, E.1
-
105
-
-
0344938137
-
Bax is frequently compromised in Burkitt's lymphomas with irreversible resistance to Fas-induced apoptosis
-
Gutierrez MI et al. Bax is frequently compromised in Burkitt's lymphomas with irreversible resistance to Fas-induced apoptosis. Cancer Res 1999; 59: 696-703.
-
(1999)
Cancer Res
, vol.59
, pp. 696-703
-
-
Gutierrez, M.I.1
-
107
-
-
0031018674
-
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
-
Rampino N et al. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 1997; 275: 967-969.
-
(1997)
Science
, vol.275
, pp. 967-969
-
-
Rampino, N.1
-
108
-
-
0028944271
-
Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-alpha expression in tumor cells correlates with resistance towards apoptosis
-
Bargou RC et al. Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis. Int J Cancer 1995; 60: 854-859.
-
(1995)
Int J Cancer
, vol.60
, pp. 854-859
-
-
Bargou, R.C.1
-
109
-
-
0029045784
-
Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma
-
Krajewski S et al. Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Res 1995; 55: 4471-4478.
-
(1995)
Cancer Res
, vol.55
, pp. 4471-4478
-
-
Krajewski, S.1
-
110
-
-
0037570803
-
Expression of bax and p53 proteins in the tumorigenesis and progression of breast carcinomas
-
Redondo M et al. Expression of bax and p53 proteins in the tumorigenesis and progression of breast carcinomas. Tumour Biol 2003; 24: 23-31.
-
(2003)
Tumour Biol
, vol.24
, pp. 23-31
-
-
Redondo, M.1
-
111
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy N et al. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. Embo J 1997; 16: 6914-6925.
-
(1997)
Embo J
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
-
112
-
-
0035920126
-
X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and-7 in distinct modes
-
Suzuki Y et al. X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and-7 in distinct modes. J Biol Chem 2001; 276: 27058-27063.
-
(2001)
J Biol Chem
, vol.276
, pp. 27058-27063
-
-
Suzuki, Y.1
-
113
-
-
0035793557
-
Livin, a novel inhibitor of apoptosis protein family member
-
Kasof GM, Gomes BC. Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem 2001; 276: 3238-3246.
-
(2001)
J Biol Chem
, vol.276
, pp. 3238-3246
-
-
Kasof, G.M.1
Gomes, B.C.2
-
114
-
-
1942534018
-
Regulation of apoptosis proteins in cancer cells by ubiquitin
-
Zhang HG et al. Regulation of apoptosis proteins in cancer cells by ubiquitin. Oncogene 2004; 23: 2009-2015.
-
(2004)
Oncogene
, vol.23
, pp. 2009-2015
-
-
Zhang, H.G.1
-
115
-
-
0032403126
-
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
-
Tamm I et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 1998; 58: 5315-5320.
-
(1998)
Cancer Res
, vol.58
, pp. 5315-5320
-
-
Tamm, I.1
-
116
-
-
4544261227
-
An IAP-IAP complex inhibits apoptosis
-
Dohi T et al. An IAP-IAP complex inhibits apoptosis. J Biol Chem 2004; 279: 34087-34090.
-
(2004)
J Biol Chem
, vol.279
, pp. 34087-34090
-
-
Dohi, T.1
-
117
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C et al. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000; 102: 33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
-
118
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
Liu Z et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature 2000; 408: 1004-1008.
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.1
-
119
-
-
0035156848
-
Identification of XAF1 as an antagonist of XIAP anti-Caspase activity
-
Liston P et al. Identification of XAF1 as an antagonist of XIAP anti-Caspase activity. Nat Cell Biol 2001; 3: 128-133.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 128-133
-
-
Liston, P.1
-
120
-
-
0034672506
-
Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines
-
Fong WG et al. Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines. Genomics 2000; 70: 113-122.
-
(2000)
Genomics
, vol.70
, pp. 113-122
-
-
Fong, W.G.1
-
121
-
-
0242442595
-
Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas
-
Byun DS et al. Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas. Cancer Res 2003; 63: 7068-7075.
-
(2003)
Cancer Res
, vol.63
, pp. 7068-7075
-
-
Byun, D.S.1
-
122
-
-
0031984247
-
Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation
-
Adida C et al. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am J Pathol 1998; 152: 43-49.
-
(1998)
Am J Pathol
, vol.152
, pp. 43-49
-
-
Adida, C.1
-
123
-
-
0346250160
-
Survivin, versatile modulation of cell division and apoptosis in cancer
-
Altieri DC. Survivin, versatile modulation of cell division and apoptosis in cancer. Oncogene 2003; 22: 8581-8589.
-
(2003)
Oncogene
, vol.22
, pp. 8581-8589
-
-
Altieri, D.C.1
-
124
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917-921.
-
(1997)
Nat Med
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
125
-
-
0141595100
-
Survivin study: What is the next wave?
-
Li F. Survivin study: what is the next wave? J Cell Physiol 2003; 197: 8-29.
-
(2003)
J Cell Physiol
, vol.197
, pp. 8-29
-
-
Li, F.1
-
126
-
-
0033980409
-
Expression of survivin and its relationship to loss of apoptosis in breast carcinomas
-
Tanaka K et al. Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clin Cancer Res 2000; 6: 127-134.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 127-134
-
-
Tanaka, K.1
-
127
-
-
0037128687
-
Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma
-
Sarela AI et al. Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br J Cancer 2002; 86: 886-892.
-
(2002)
Br J Cancer
, vol.86
, pp. 886-892
-
-
Sarela, A.I.1
-
128
-
-
0033661699
-
Role of survivin, whose gene is mapped to 17q25, in human neuroblastoma and identification of a novel dominant-negative isoform, survivin-beta/2B
-
Islam A et al. Role of survivin, whose gene is mapped to 17q25, in human neuroblastoma and identification of a novel dominant-negative isoform, survivin-beta/2B. Med Pediatr Oncol 2000; 35: 550-553.
-
(2000)
Med Pediatr Oncol
, vol.35
, pp. 550-553
-
-
Islam, A.1
-
129
-
-
0035964487
-
DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes
-
Hattori M, Sakamoto H, Satoh K, Yamamoto T. DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes. Cancer Lett 2001; 169: 155-164.
-
(2001)
Cancer Lett
, vol.169
, pp. 155-164
-
-
Hattori, M.1
Sakamoto, H.2
Satoh, K.3
Yamamoto, T.4
-
130
-
-
0037012343
-
Activation of cancer-specific gene expression by the survivin promoter
-
Bao R et al. Activation of cancer-specific gene expression by the survivin promoter. J Natl Cancer Inst 2002; 94: 522-528.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 522-528
-
-
Bao, R.1
-
131
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
-
Hoffman WH et al. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 2002; 277: 3247-3257.
-
(2002)
J Biol Chem
, vol.277
, pp. 3247-3257
-
-
Hoffman, W.H.1
-
132
-
-
0036747409
-
A role for survivin in radioresistance of pancreatic cancer cells
-
Asanuma K et al. A role for survivin in radioresistance of pancreatic cancer cells. Jpn J Cancer Res 2002; 93: 1057-1062.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 1057-1062
-
-
Asanuma, K.1
-
133
-
-
0032533494
-
Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer
-
Kawasaki H et al. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res 1998; 58: 5071-5074.
-
(1998)
Cancer Res
, vol.58
, pp. 5071-5074
-
-
Kawasaki, H.1
-
134
-
-
3843099444
-
Survivin expression is a prognostic marker in pancreatic cancer patients
-
Kami K et al. Survivin expression is a prognostic marker in pancreatic cancer patients. Surgery 2004; 136: 443-448.
-
(2004)
Surgery
, vol.136
, pp. 443-448
-
-
Kami, K.1
-
135
-
-
0034795822
-
Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53
-
Grossman D et al. Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53. J Clin Invest 2001; 108: 991-999.
-
(2001)
J Clin Invest
, vol.108
, pp. 991-999
-
-
Grossman, D.1
-
136
-
-
0034789355
-
Cancer gene therapy using a survivin mutant adenovirus
-
Mesri M et al. Cancer gene therapy using a survivin mutant adenovirus. J Clin Invest 2001; 108: 981-990.
-
(2001)
J Clin Invest
, vol.108
, pp. 981-990
-
-
Mesri, M.1
-
137
-
-
1342332363
-
Antisense to apoptosis inhibitors facilitates chemotherapy and TRAIL-induced death signaling
-
Zangemeister-Wittke U. Antisense to apoptosis inhibitors facilitates chemotherapy and TRAIL-induced death signaling. Ann N Y Acad Sci 2003; 1002: 90-94.
-
(2003)
Ann N y Acad Sci
, vol.1002
, pp. 90-94
-
-
Zangemeister-Wittke, U.1
-
138
-
-
0033258543
-
Pleiotropic cell-division defects and apoptosis induced by interference with survivin function
-
Li F et al. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat Cell Biol 1999; 1: 461-466.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 461-466
-
-
Li, F.1
-
139
-
-
0026669469
-
Kinzler KW. p53 function and dysfunction
-
Vogelstein B, Kinzler KW. p53 function and dysfunction. Cell 1992; 70: 523-526.
-
(1992)
Cell
, vol.70
, pp. 523-526
-
-
Vogelstein, B.1
-
141
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak K et al. A model for p53-induced apoptosis. Nature 1997; 389: 300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
-
142
-
-
0031743648
-
P53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller M et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 1998; 188: 2033-2045.
-
(1998)
J Exp Med
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
-
143
-
-
0031038137
-
Bax suppresses tumorigenesis and stimulates apoptosis in vivo
-
Yin C, Knudson CM, Korsmeyer SJ, Van Dyke T. Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature 1997; 385: 637-640.
-
(1997)
Nature
, vol.385
, pp. 637-640
-
-
Yin, C.1
Knudson, C.M.2
Korsmeyer, S.J.3
Van Dyke, T.4
-
144
-
-
0037452759
-
PUMA mediates the apoptotic response to p53 in colorectal cancer cells
-
Yu J et al. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci USA 2003; 100: 1931-1936.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1931-1936
-
-
Yu, J.1
-
145
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
-
Marchenko ND, Zaika A, Moll UM. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 2000; 275: 16202-16212.
-
(2000)
J Biol Chem
, vol.275
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
146
-
-
0037349289
-
P53 has a direct apoptogenic role at the mitochondria
-
Mihara M et al. p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003; 11: 577-590.
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
-
147
-
-
0036287040
-
The EGF/ErbB receptor family and apoptosis
-
Danielsen AJ, Maihle NJ. The EGF/ErbB receptor family and apoptosis. Growth Factors 2002; 20: 1-15.
-
(2002)
Growth Factors
, vol.20
, pp. 1-15
-
-
Danielsen, A.J.1
Maihle, N.J.2
-
148
-
-
0029824114
-
Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification
-
Ram TG, Ethier SP. Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification. Cell Growth Differ 1996; 7: 551-561.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 551-561
-
-
Ram, T.G.1
Ethier, S.P.2
-
149
-
-
0034708482
-
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
-
Toker A, Newton AC. Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. J Biol Chem 2000; 275: 8271-8274.
-
(2000)
J Biol Chem
, vol.275
, pp. 8271-8274
-
-
Toker, A.1
Newton, A.C.2
-
150
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91: 231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
-
151
-
-
0033588217
-
Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis
-
Sabbatini P, McCormick F. Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis. J Biol Chem 1999; 274: 24263-24269.
-
(1999)
J Biol Chem
, vol.274
, pp. 24263-24269
-
-
Sabbatini, P.1
McCormick, F.2
-
152
-
-
1242317030
-
Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP)
-
Dan HC et al. Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J Biol Chem 2004; 279: 5405-5412.
-
(2004)
J Biol Chem
, vol.279
, pp. 5405-5412
-
-
Dan, H.C.1
-
153
-
-
0033517840
-
Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells
-
Tran J et al. Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells. Biochem Biophys Res Commun 1999; 264: 781-788.
-
(1999)
Biochem Biophys Res Commun
, vol.264
, pp. 781-788
-
-
Tran, J.1
-
154
-
-
0034841661
-
Phosphoinositide 3-kinase signalling in breast cancer: How big a role might it play?
-
Fry MJ. Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play? Breast Cancer Res 2001; 3: 304-312.
-
(2001)
Breast Cancer Res
, vol.3
, pp. 304-312
-
-
Fry, M.J.1
-
155
-
-
0035008874
-
Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression
-
Hutchinson J et al. Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression. Mol Cell Biol 2001; 21: 2203-2212.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2203-2212
-
-
Hutchinson, J.1
-
156
-
-
0034907425
-
Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug-and Fas-induced apoptosis by a JNK independent pathway
-
O'Gorman DM, McKenna SL, McGahon AJ, Cotter TG. Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug-and Fas-induced apoptosis by a JNK independent pathway. Leuk Res 2001; 25: 801-811.
-
(2001)
Leuk Res
, vol.25
, pp. 801-811
-
-
O'Gorman, D.M.1
McKenna, S.L.2
McGahon, A.J.3
Cotter, T.G.4
-
157
-
-
0032558822
-
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
-
Haas-Kogan D et al. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr Biol 1998; 8: 1195-1198.
-
(1998)
Curr Biol
, vol.8
, pp. 1195-1198
-
-
Haas-Kogan, D.1
-
158
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa] B activity
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 2000; 18: 621-663.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
159
-
-
0036719081
-
Propapoptotic effects of NF-kappaB in LNCaP prostate cancer cells lead to serine protease activation
-
Kimura K, Gelmann EP. Propapoptotic effects of NF-kappaB in LNCaP prostate cancer cells lead to serine protease activation. Cell Death Differ 2002; 9: 972-980.
-
(2002)
Cell Death Differ
, vol.9
, pp. 972-980
-
-
Kimura, K.1
Gelmann, E.P.2
-
160
-
-
0032588794
-
NF-kappaB regulates Fas/APO-1/CD95-and TCR-mediated apoptosis of T lymphocytes
-
Dudley E et al. NF-kappaB regulates Fas/APO-1/CD95-and TCR-mediated apoptosis of T lymphocytes. Eur J Immunol 1999; 29: 878-886.
-
(1999)
Eur J Immunol
, vol.29
, pp. 878-886
-
-
Dudley, E.1
-
161
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002; 2: 301-310.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
162
-
-
1642553460
-
To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis
-
Kucharczak J, Simmons MJ, Fan Y, Gelinas C. To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis. Oncogene 2003; 22: 8961-8982.
-
(2003)
Oncogene
, vol.22
, pp. 8961-8982
-
-
Kucharczak, J.1
Simmons, M.J.2
Fan, Y.3
Gelinas, C.4
-
163
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003; 114: 181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
164
-
-
0033557805
-
Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
-
Grumont RJ, Rourke IJ, Gerondakis S. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev 1999; 13: 400-411.
-
(1999)
Genes Dev
, vol.13
, pp. 400-411
-
-
Grumont, R.J.1
Rourke, I.J.2
Gerondakis, S.3
-
165
-
-
0038103154
-
NF-kappa B2/p100 induces Bcl-2 expression
-
Viatour P et al. NF-kappa B2/p100 induces Bcl-2 expression. Leukemia 2003; 17: 1349-1356.
-
(2003)
Leukemia
, vol.17
, pp. 1349-1356
-
-
Viatour, P.1
-
166
-
-
2342426324
-
Expression of the IAPs in multidrug resistant tumor cells
-
Notarbartolo M et al. Expression of the IAPs in multidrug resistant tumor cells. Oncol Rep 2004; 11: 133-136.
-
(2004)
Oncol Rep
, vol.11
, pp. 133-136
-
-
Notarbartolo, M.1
-
167
-
-
0346435107
-
Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B
-
Wang Q, Wang X, Evers BM. Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B. J Biol Chem 2003; 278: 51091-51099.
-
(2003)
J Biol Chem
, vol.278
, pp. 51091-51099
-
-
Wang, Q.1
Wang, X.2
Evers, B.M.3
-
168
-
-
0034616122
-
Regulation of FasL by NF-kappaB and AP-1 in Fas-dependent thymineless death of human colon carcinoma cells
-
Harwood FG et al. Regulation of FasL by NF-kappaB and AP-1 in Fas-dependent thymineless death of human colon carcinoma cells. J Biol Chem 2000; 275: 10023-10029.
-
(2000)
J Biol Chem
, vol.275
, pp. 10023-10029
-
-
Harwood, F.G.1
-
169
-
-
0037376895
-
NF-kappaB in cancer: A marked target
-
Lin A, Karin M. NF-kappaB in cancer: a marked target. Semin Cancer Biol 2003; 13: 107-114.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 107-114
-
-
Lin, A.1
Karin, M.2
-
170
-
-
1542644825
-
NF-kappaB in mammary gland development and breast cancer
-
Cao Y, Karin M. NF-kappaB in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 2003; 8: 215-223.
-
(2003)
J Mammary Gland Biol Neoplasia
, vol.8
, pp. 215-223
-
-
Cao, Y.1
Karin, M.2
-
171
-
-
0036651553
-
Reduced response of prostate cancer cells to TRAIL is modulated by NFkappaB-mediated inhibition of caspases and Bid activation
-
Eid MA, Lewis RW, Abdel-Mageed AB, Kumar MV. Reduced response of prostate cancer cells to TRAIL is modulated by NFkappaB-mediated inhibition of caspases and Bid activation. Int J Oncol 2002; 21: 111-117.
-
(2002)
Int J Oncol
, vol.21
, pp. 111-117
-
-
Eid, M.A.1
Lewis, R.W.2
Abdel-Mageed, A.B.3
Kumar, M.V.4
-
172
-
-
1342284288
-
NF-kappaB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines
-
Meli M et al. NF-kappaB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines. Ann N Y Acad Sci 2003; 1010: 232-236.
-
(2003)
Ann N y Acad Sci
, vol.1010
, pp. 232-236
-
-
Meli, M.1
-
173
-
-
0036122242
-
Involvement of hypoxia-inducible factor 1 in human cancer
-
Semenza GL. Involvement of hypoxia-inducible factor 1 in human cancer. Intern Med 2002; 41: 79-83.
-
(2002)
Intern Med
, vol.41
, pp. 79-83
-
-
Semenza, G.L.1
-
174
-
-
0842333201
-
Prognostic significance of HIF-1 alpha overexpression in human pancreatic cancer
-
Shibaji T et al. Prognostic significance of HIF-1 alpha overexpression in human pancreatic cancer. Anticancer Res 2003; 23: 4721-4727.
-
(2003)
Anticancer Res
, vol.23
, pp. 4721-4727
-
-
Shibaji, T.1
-
175
-
-
0035418621
-
Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
-
Akakura N et al. Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res 2001; 61: 6548-6554.
-
(2001)
Cancer Res
, vol.61
, pp. 6548-6554
-
-
Akakura, N.1
-
176
-
-
1542344522
-
Hypoxia-inducible factor-1 and oncogenic signalling
-
Bardos JI, Ashcroft M. Hypoxia-inducible factor-1 and oncogenic signalling. Bioessays 2004; 26: 262-269.
-
(2004)
Bioessays
, vol.26
, pp. 262-269
-
-
Bardos, J.I.1
Ashcroft, M.2
-
177
-
-
1542408478
-
Tumour hypoxia: Impact on biology, prognosis and treatment of solid malignant tumours
-
Weinmann M, Belka C, Plasswilm L. Tumour hypoxia: impact on biology, prognosis and treatment of solid malignant tumours. Onkologie 2004; 27: 83-90.
-
(2004)
Onkologie
, vol.27
, pp. 83-90
-
-
Weinmann, M.1
Belka, C.2
Plasswilm, L.3
-
179
-
-
2342588053
-
Molecular ordering of hypoxia-induced apoptosis: Critical involvement of the mitochondrial death pathway in a FADD/caspase-8 independent manner
-
Weinmann M et al. Molecular ordering of hypoxia-induced apoptosis: critical involvement of the mitochondrial death pathway in a FADD/caspase-8 independent manner. Oncogene 2004; 23: 3757-3769.
-
(2004)
Oncogene
, vol.23
, pp. 3757-3769
-
-
Weinmann, M.1
-
180
-
-
1842861767
-
Hypoxia and CoCl2 protect HepG2 cells against serum deprivation-and t-BHP-induced apoptosis: A possible anti-apoptotic role for HIF-1
-
Piret JP et al. Hypoxia and CoCl2 protect HepG2 cells against serum deprivation-and t-BHP-induced apoptosis: a possible anti-apoptotic role for HIF-1. Exp Cell Res 2004; 295: 340-349.
-
(2004)
Exp Cell Res
, vol.295
, pp. 340-349
-
-
Piret, J.P.1
-
181
-
-
0042845994
-
Apoptosis-resistance of hypoxic cells: Multiple factors involved and a role for IAP-2
-
Dong Z, Wang JZ, Yu F, Venkatachalam MA. Apoptosis-resistance of hypoxic cells: multiple factors involved and a role for IAP-2. Am J Pathol 2003; 163: 663-671.
-
(2003)
Am J Pathol
, vol.163
, pp. 663-671
-
-
Dong, Z.1
Wang, J.Z.2
Yu, F.3
Venkatachalam, M.A.4
-
182
-
-
1542305379
-
Hypoxia selection of death-resistant cells. A role for Bcl-X(L)
-
Dong Z, Wang J. Hypoxia selection of death-resistant cells. A role for Bcl-X(L). J Biol Chem 2004; 279: 9215-9221.
-
(2004)
J Biol Chem
, vol.279
, pp. 9215-9221
-
-
Dong, Z.1
Wang, J.2
-
183
-
-
1842583652
-
Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine
-
Yokoi K, Fidler IJ. Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine. Clin Cancer Res 2004; 10: 2299-2306.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2299-2306
-
-
Yokoi, K.1
Fidler, I.J.2
-
184
-
-
4243182684
-
Tumor-specific gene expression using the survivin promoter is further increased by hypoxia
-
Yang L et al. Tumor-specific gene expression using the survivin promoter is further increased by hypoxia. Gene Ther 2004; 11: 1215-1223.
-
(2004)
Gene Ther
, vol.11
, pp. 1215-1223
-
-
Yang, L.1
-
185
-
-
0035884701
-
HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
-
Sowter HM et al. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 2001; 61: 6669-6673.
-
(2001)
Cancer Res
, vol.61
, pp. 6669-6673
-
-
Sowter, H.M.1
-
186
-
-
3442888541
-
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer
-
Okami J, Simeone DM, Logsdon CD. Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. Cancer Res 2004; 64: 5338-5346.
-
(2004)
Cancer Res
, vol.64
, pp. 5338-5346
-
-
Okami, J.1
Simeone, D.M.2
Logsdon, C.D.3
-
187
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha
-
An WG et al. Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha. Nature 1998; 392: 405-408.
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
-
188
-
-
0034988045
-
Induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: New tricks from a (not so) old drug
-
Mitsiades N, Poulaki V, Mitsiades CS, Anderson KC. Induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: new tricks from a (not so) old drug. Expert Opin Investig Drugs 2001; 10: 1075-1084.
-
(2001)
Expert Opin Investig Drugs
, vol.10
, pp. 1075-1084
-
-
Mitsiades, N.1
Poulaki, V.2
Mitsiades, C.S.3
Anderson, K.C.4
-
189
-
-
0033032317
-
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
-
Sethi T et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med 1999; 5: 662-668.
-
(1999)
Nat Med
, vol.5
, pp. 662-668
-
-
Sethi, T.1
-
191
-
-
0347383715
-
Matrix metalloproteinases and their tissue inhibitors direct cell fate during cancer development
-
Hojilla CV, Mohammed FF, Khokha R. Matrix metalloproteinases and their tissue inhibitors direct cell fate during cancer development. Br J Cancer 2003; 89: 1817-1821.
-
(2003)
Br J Cancer
, vol.89
, pp. 1817-1821
-
-
Hojilla, C.V.1
Mohammed, F.F.2
Khokha, R.3
-
192
-
-
0034467122
-
Metalloproteinases: Role in breast carcinogenesis, invasion and metastasis
-
Duffy MJ et al. Metalloproteinases: role in breast carcinogenesis, invasion and metastasis. Breast Cancer Res 2000; 2: 252-257.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 252-257
-
-
Duffy, M.J.1
-
193
-
-
2442684321
-
Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells
-
Strand S et al. Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells. Oncogene 2004; 23: 3732-3736.
-
(2004)
Oncogene
, vol.23
, pp. 3732-3736
-
-
Strand, S.1
-
194
-
-
0035863471
-
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity
-
Mitsiades N et al. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer Res 2001; 61: 577-581.
-
(2001)
Cancer Res
, vol.61
, pp. 577-581
-
-
Mitsiades, N.1
-
195
-
-
0036791136
-
Matrilysin (matrix metalloproteinase-7) selects for apoptosis-resistant mammary cells in vivo
-
Vargo-Gogola T, Fingleton B, Crawford HC, Matrisian LM. Matrilysin (matrix metalloproteinase-7) selects for apoptosis-resistant mammary cells in vivo. Cancer Res 2002; 62: 5559-5563.
-
(2002)
Cancer Res
, vol.62
, pp. 5559-5563
-
-
Vargo-Gogola, T.1
Fingleton, B.2
Crawford, H.C.3
Matrisian, L.M.4
-
196
-
-
0035899331
-
Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells
-
Aoudjit F, Vuori K. Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene 2001; 20: 4995-5004.
-
(2001)
Oncogene
, vol.20
, pp. 4995-5004
-
-
Aoudjit, F.1
Vuori, K.2
-
197
-
-
1542328956
-
A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors
-
Jan Y et al. A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors. Cell 2004; 116: 751-762.
-
(2004)
Cell
, vol.116
, pp. 751-762
-
-
Jan, Y.1
-
198
-
-
0033166087
-
Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand
-
Ambar BB et al. Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand. Hum Gene Ther 1999; 10: 1641-1648.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1641-1648
-
-
Ambar, B.B.1
-
199
-
-
0036288826
-
Caspase-8 gene therapy using the human telomerase reverse transcriptase promoter for malignant glioma cells
-
Komata T et al. Caspase-8 gene therapy using the human telomerase reverse transcriptase promoter for malignant glioma cells. Hum Gene Ther 2002; 13: 1015-1025.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1015-1025
-
-
Komata, T.1
-
200
-
-
0034674306
-
Transduction of Apaf-1 or caspase-9 induces apoptosis in A-172 cells that are resistant to p53-mediated apoptosis
-
Shinoura N et al. Transduction of Apaf-1 or caspase-9 induces apoptosis in A-172 cells that are resistant to p53-mediated apoptosis. Biochem Biophys Res Commun 2000; 272: 667-673.
-
(2000)
Biochem Biophys Res Commun
, vol.272
, pp. 667-673
-
-
Shinoura, N.1
-
201
-
-
0034194022
-
Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells
-
Shinoura N et al. Adenovirus-mediated transfer of caspase-3 with Fas ligand induces drastic apoptosis in U-373MG glioma cells. Exp Cell Res 2000; 256: 423-433.
-
(2000)
Exp Cell Res
, vol.256
, pp. 423-433
-
-
Shinoura, N.1
-
202
-
-
0035136282
-
Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer
-
Li X et al. Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer. Cancer Res 2001; 61: 186-191.
-
(2001)
Cancer Res
, vol.61
, pp. 186-191
-
-
Li, X.1
-
203
-
-
0035144922
-
Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines
-
Pataer A et al. Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines. J Thorac Cardiovasc Surg 2001; 121: 61-67.
-
(2001)
J Thorac Cardiovasc Surg
, vol.121
, pp. 61-67
-
-
Pataer, A.1
-
204
-
-
0035147560
-
Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer
-
Park WS et al. Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer. J Pathol 2001; 193: 162-168.
-
(2001)
J Pathol
, vol.193
, pp. 162-168
-
-
Park, W.S.1
-
205
-
-
9144234685
-
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
-
Schimmer AD et al. Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. Cancer Cell 2004; 5: 25-35.
-
(2004)
Cancer Cell
, vol.5
, pp. 25-35
-
-
Schimmer, A.D.1
-
207
-
-
0029915677
-
Extensive apoptosis in ductal carcinoma in situ of the breast
-
Bodis S et al. Extensive apoptosis in ductal carcinoma in situ of the breast. Cancer 1996; 77: 1831-1835.
-
(1996)
Cancer
, vol.77
, pp. 1831-1835
-
-
Bodis, S.1
-
208
-
-
0030065185
-
Quantitation of multistage carcinogenesis in rat liver
-
Pitot HC et al. Quantitation of multistage carcinogenesis in rat liver. Toxicol Pathol 1996; 24: 119-128.
-
(1996)
Toxicol Pathol
, vol.24
, pp. 119-128
-
-
Pitot, H.C.1
|