Molecular ordering of hypoxia-induced apoptosis: Critical involvement of the mitochondrial death pathway in a FADD/caspase-8 independent manner

Oncogene

Volumn 23, Issue 21, 2004, Pages 3757-3769

  Weinmann, Martin ^a   Jendrossek, Verena ^a   Handrick, Rene ^a   Güner, Dilek ^b   Goecke, Barbara ^a   Belka, Claus ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Apoptosis; Bcl 2; Caspase 8; FADD; Hypoxia; Mitochondria

Indexed keywords

CASPASE 8; CASPASE 9; FAS ASSOCIATED DEATH DOMAIN PROTEIN; PROTEIN BCL 2; CARRIER PROTEIN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; DNA BINDING PROTEIN; FADD PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; PROTEIN P53; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; CELL MUTANT; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE FUNCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; LEUKEMIA CELL LINE; MITOCHONDRION; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL HYPOXIA; METABOLISM; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; CELL HYPOXIA; DNA-BINDING PROTEINS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; JURKAT CELLS; MITOCHONDRIA; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 2342588053     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207481     Document Type: Article

References (64)

1. Alarcon RM, Denko NC and Giaccia AJ. (2001). Novartis Found. Symp., 240, 115-128 discussion 128-132.
2. Banasiak KJ, Cronin T and Haddad GG. (1999). Brain Res. Mol. Brain Res., 72, 214-225.
3. Banasiak KJ and Haddad GG. (1998). Brain Res., 797, 295-304.
4. Belka C, Betsch A, Marini P, Jendrossek V, Bamberg M and Budach W. (2003a). Strahlenther. Onkol., 179, 141-151.
5. Belka C and Budach W. (2002). Int. J. Radiat. Biol., 78, 643-658.
6. Belka C, Gruber C, Jendrossek V, Wesselborg S and Budach W. (2003b). Oncogene, 22, 176-185.
7. Belka C, Heinrich V, Marini P, Faltin H, Schulze-Osthoff K, Bamberg M and Budach W. (1999a). Int. J. Radiat. Biol., 75, 1257-1264.
8. Belka C, Marini P, Budach W, Schulze-Osthoff K, Lang F, Gulbins E and Bamberg M. (1998). Radiat. Res., 149, 588-595.
9. Belka C, Marini P, Lepple-Wienhues A, Budach W, Jekle A, Los M, Lang F, Schulze-Osthoff K, Gulbins E and Bamberg M. (1999b). Oncogene, 18, 4983-4992.
10. Belka C, Rudner J, Wesselborg S, Stepczynska A, Marini P, Lepple-Wienhues A, Faltin H, Bamberg M, Budach W and Schulze-Osthoff K. (2000). Oncogene, 19, 1181-1190.
11. Bialik S, Geenen DL, Sasson IE, Cheng R, Horner JW, Evans SM, Lord EM, Koch CJ and Kitsis RN. (1997). J. Clin. Invest., 100, 1363-1372.
12. Blagosklonny MV, An WG, Romanova LY, Trepel J, Fojo T and Neckers L. (1998). J. Biol. Chem., 273, 11995-11998.
13. Chao W, Shen Y, Li L and Rosenzweig A. (2002). J. Biol. Chem., 277, 31639-31645.
14. Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T and Korsmeyer SJ. (2001). Mol. Cell, 8, 705-711.
15. Chinnaiyan AM, O'Rourke K, Tewari M and Dixit VM. (1995). Cell, 81, 505-512.
16. Engels IH, Stepczynska A, Stroh C, Lauber K, Berg C, Schwenzer R, Wajant H, Janicke RU, Porter AG, Belka C, Gregor M, Schulze-Osthoff K and Wesselborg S. (2000). Oncogene, 19, 4563-4573.
17. Felderhoff-Mueser U, Taylor DL, Greenwood K, Kozma M, Stibenz D, Joashi UC, Edwards AD and Mehmet H. (2000). Brain Pathol., 10, 17-29.
18. Ferrari D, Stepczynska A, Los M, Wesselborg S and Schulze-Osthoff K. (1998). J. Exp. Med., 188, 979-984.
19. Fischer U, Janicke RU and Schulze-Osthoff K. (2003). Cell Death Differ., 10, 76-100.
20. Gibson ME, Han BH, Choi J, Knudson CM, Korsmeyer SJ, Parsadanian M and Holtzman DM. (2001). Mol. Med., 7, 644-655.
21. Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW and Giaccia AJ. (1996). Nature, 379, 88-91.
22. Harris AL. (2002). Nat. Rev. Cancer, 2, 38-47.
23. Igney FH and Krammer PH. (2002). Nat. Rev. Cancer, 2, 277-288.
24. Jendrossek V, Handrick R and Belka C. (2003a). FASEB. J., 17, 1547-1549.
25. Jendrossek V, Muller I, Eibl H and Belka C. (2003b). Oncogene, 22, 2621-2631.
26. Khurana P, Ashraf QM, Mishra OP and Delivoria-Papadopoulos M. (2002). Neurochem. Res., 27, 931-938.
27. Kim CY, Tsai MH, Osmanian C, Graeber TG, Lee JE, Giffard RG, DiPaolo JA, Peehl DM and Giaccia AJ. (1997). Cancer Res., 57, 4200-4204.
28. Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ and Ashkenazi A. (2000), Immunity, 12, 611-620.
29. Kischkel FC, Lawrence DA, Tinel A, LeBlanc H, Virmani A, Schow P, Gazdar A, Blenis J, Arnott D and Ashkenazi A, (2001). J. Biol. Chem., 2, 2.
30. Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD. (1997). Science, 275, 1132-1136.
31. Kowaltowski AJ, Cosso RG, Campos CB and Fiskum G. (2002). J. Biol. Chem., 277, 42802-42807.
32. Li H, Zhu H, Xu CJ and Yuan J. (1998). Cell, 94, 491-501.
33. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES and Wang X. (1997). Cell, 91, 479-489.
34. Lopez-Hernandez FJ, Ortiz MA, Bayon Y and Piedrafita FJ. (2003). Cell Death Differ., 24, 24.
35. Malhotra R, Lin Z, Vincenz C and Brosius III FC. (2001). Am. J. Physiol. Cell Physiol., 281, C1596-C1603.
36. Medema JP, Scaffidi C, Kischkel FC, Shevchenko A, Mann M, Krammer PH and Peter ME. (1997). EMBO J., 16, 2794-2804.
37. Mogi M, Fukuo K, Yang J, Suhara T and Ogihara T. (2001). Lab. Invest., 81, 177-184.
38. Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME and Dixit VM. (1996). Cell, 85, 817-827.
39. Muzio M, Stockwell BR, Stennicke HR, Salvesen GS and Dixit VM. (1998). J. Biol. Chem., 273, 2926-2930.
40. Newton K and Strasser A. (2000). J. Exp. Med., 191, 195-200.
41. Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T and Tanaka N. (2000). Science, 288, 1053-1058.
42. Park WY, Hwang CI, Im CN, Kang MJ, Woo JH, Kim JH, Kim YS, Kim H, Kim KA, Yu HJ, Lee SJ, Lee YS and Seo JS. (2002). Oncogene, 21, 8521-8528.
43. Qin JZ, Chaturvedi V, Denning MF, Bacon P, Panella J, Choubey D and Nickoloff BJ. (2002). Oncogene, 21, 2991-3002.
44. Renz A, Berdel WE, Kreuter M, Belka C, Schulze-Osthoff K and Los M. (2001). Blood, 98, 1542-1548.
45. Rudner J, Belka C, Marini P, Wagner RJ, Faltin H, Lepple-Wienhues A, Bamberg M and Budach W. (2001a). Int. J. Radiat. Biol., 77, 1-11.
46. Rudner J, Jendrossek V and Belka C. (2002). Apoptosis, 7, 441-447.
47. Rudner J, Lepple-Wienhues A, Budach W, Berschauer J, Friedrich B, Wesselborg S, Schulze-Osthoff K and Belka C. (2001b). J. Cell. Sci., 114, 4161-4172.
48. Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, Debatin KM, Krammer PH and Peter ME. (1998). EMBO J., 17, 1675-1687.
49. Shimizu S, Eguchi Y, Kamiike W, Itoh Y, Hasegawa J, Yamabe K, Otsuki Y, Matsuda H and Tsujimoto Y. (1996). Cancer Res., 56, 2161-2166.
50. Shimizu S, Eguchi Y, Kosaka H, Kamiike W, Matsuda H and Tsujimoto Y. (1995). Nature, 374, 811-813.
51. Soengas MS, Alarcon RM, Yoshida H, Giaccia AJ, Hakem R, Mak TW and Lowe SW. (1999). Science, 284, 156-159.
52. Steinbach JP, Wolburg H, Klumpp A, Probst H and Weller M, (2003). Cell Death Differ., 10, 823-832.
53. Stepczynska A, Lauber K, Engels IH, Janssen O, Kabelitz D, Wesselborg S and Schulze-Osthoff K. (2001). Oncogene, 20, 1193-1202.
54. Suzuki H, Tomida A and Tsuruo T. (2001). Oncogene, 20, 5779-5788.
55. Tamatani M, Ogawa S and Tohyama M. (1998). Brain. Res. Mol. Brain Res., 58, 27-39.
56. Tsujimoto Y, Shimizu S, Eguchi Y, Kamiike W and Matsuda H. (1997). Leukemia, 11, 380-382.
57. Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, Moritz RL, Simpson RJ and Vaux DL. (2000). Cell, 102, 43-53.
58. von Haefen C, Wieder T, Gillissen B, Starck L, Graupner V, Borken B and Daniel PT. (2002). Oncogene, 21, 4009-4019.
59. Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB and Korsmeyer SJ. (2001). Science, 292, 727-730.
60. Weinmann M, Marini P, Jendrossek V, Betsch A, Goecke B, Budach W and Belka C. (2004). Int. J. Radiat. Oncol. Biol. Phys., 58, 386-396.
61. Wieder T, Essmann F, Prokop A, Schmelz K, Schulze-Osthoff K, Beyaert R, Dorken B and Daniel PT. (2001). Blood, 97, 1378-1387.
62. Yaniv G, Shilkrut M, Lotan R, Berke G, Larisch S and Binah O. (2002). Cardiovasc. Res., 54, 611-623.
63. Yoshimura S, Banno Y, Nakashima S, Takenaka K, Sakai H, Nishimura Y, Sakai N, Shimizu S, Eguchi Y, Tsujimoto Y and Nozawa Y. (1998). J. Biol. Chem., 273, 6921-6927.
64. Zhu H, McElwee-Witmer S, Perrone M, Clark KL and Zilberstein A. (2000). Cell Death Differ., 7, 773-784.