Somatic mutations in the death domain of the Fas (Apo-I/CD95) gene in gastric cancer

Journal of Pathology

Volumn 193, Issue 2, 2001, Pages 162-168

  Park, Won Sang ^a   Oh, Ro Ra ^a   Kim, Young Sil ^a   Park, Jik Young ^a   Lee, Sug Hyung ^a   Shin, Min Sun ^a   Kim, Su Young ^a   Kim, Pum Joon ^a   Lee, Hun Kyung ^a   Yoo, Nam Jin ^a   Lee, Jung Young ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Fas; Gastric cancer; LOH; Mutation

Indexed keywords

FAS ANTIGEN;

ADULT; AGED; ALLELE; APOPTOSIS; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL PROTECTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE INACTIVATION; GENE SEQUENCE; GENETIC CODE; GENETIC MARKER; GENETIC POLYMORPHISM; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MISSENSE MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; SINGLE STRAND CONFORMATION POLYMORPHISM; SOMATIC MUTATION; STOMACH CANCER; TUMOR DIFFERENTIATION; TUMOR GROWTH; TUMOR PROMOTION;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ALLELES; ANTIGENS, CD95; APOPTOSIS; FEMALE; GENETIC MARKERS; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MUTATION, MISSENSE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; STOMACH NEOPLASMS;

EID: 0035147560     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH759>3.0.CO;2-A     Document Type: Article

References (27)

1. Mechanism of CD95 (APO-1/Fas)-mediated apoptosis
2. Constitutive and induced expression of APO-1, a new member of the new growth factor/tumor necrosis receptor superfamily, in normal and neoplastic cells
3. Detection of soluble Fas mRNA using in situ reverse transcription-polymerase chain reaction
4. Genomic amplifications of a decoy receptor for Fas ligand in lung and colon cancer
5. FAP-1: A protein tyrosine phosphatase that associates with Fas
6. Inhibition of death receptor signals by cellular FLIP
7. Immunohistochemical evidence of aberrant bcl-2 protein expression in gastric epithelial dysplasia
8. CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia
9. Fas gene mutation in the progression of adult T cell leukemia
10. Mutations in the Fas antigen in patients with multiple myeloma
11. Somatic Fas mutations in non-Hodgkin's lymphoma: Association with extranodal disease and autoimmunity
12. Alteration of Fas (APO-1/CD95) gene in transitional cell carcinomas of urinary bladder
13. Alterations of Fas (APO-1/CD95) gene in non-small cell lung cancer
14. Alteration of Fas (APO-1/CD95) gene in cutaneous malignant melanoma
15. Bcl-2 expression and its association with kinetics in human gastric carcinomas and intestinal metaplasia
16. The two histological main types of gastric carcinoma. Diffuse and so-called intestinal type carcinoma: An attempt at histoclinical classification
17. A simple, precise and economical microdissection technique for analysis of genomic DNA from archival tissue sections
18. Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene
19. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
20. Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: A molecular and immunological analysis
21. Spontaneous development of plasmacytoid tumors in mice with defective Fas-Fas ligand interactions
22. The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis
23. NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain
24. Defective CD95/APO-1/ Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type 1a
25. Importance of changes in epithelial cell turnover during Helicobacter pylori infection in gastric carcinogenesis
26. Helicobacter pylori and intestinal- and diffuse-type gastric adenocarcinoma
27. Involvement of the CD95 (APO-1/Fas) receptor and ligand system in Helicobacter pylori-induced gastric epithelial cell apoptosis