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Volumn 6, Issue 4, 2001, Pages 253-261

XIAP: Apoptotic brake and promising therapeutic target

Author keywords

Antisense therapy; BIR; Caspases; IAP; IRES; Receptor mediated signaling; RING finger; Ubiquitin ligase; XIAP

Indexed keywords

CASPASE; CASPASE INHIBITOR; LIGASE; UBIQUITIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

EID: 0034905394     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011379307472     Document Type: Review
Times cited : (369)

References (47)
  • 9
    • 0032522738 scopus 로고    scopus 로고
    • IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
    • (1998) Embo J , vol.17 , pp. 2215-2223
    • Deveraux, Q.L.1
  • 10
    • 0033592470 scopus 로고    scopus 로고
    • NMR structure and mutagenesis of the inibitor-of-apoptosis protein XIAP
    • (1999) Nature , vol.401 , pp. 818-822
    • Sun, C.1
  • 11
    • 0034721940 scopus 로고    scopus 로고
    • NMR structure and mutagenesis of the third bir domain of the inhibitor of apoptosis protein XIAP
    • (2000) J Biol Chem , vol.275 , pp. 33777-33781
    • Sun, C.1
  • 13
    • 0032478717 scopus 로고    scopus 로고
    • A single BIR domain of XIAP sufficient for inhibiting caspases
    • (1998) J Biol Chem , vol.273 , pp. 7787-7790
    • Takahashi, R.1
  • 14
    • 0034032963 scopus 로고    scopus 로고
    • Inhibitor of apoptosis protein hILP undergoes caspase-mediated cleavage during T lymphocyte apoptosis
    • (2000) Cancer Res , vol.60 , pp. 1818-1823
    • Johnson, D.E.1
  • 16
    • 0034602928 scopus 로고    scopus 로고
    • RING domains: Master builders of molecular scaffolds?
    • (2000) J Mol Biol , vol.295 , pp. 1103-1112
    • Borden, K.L.1
  • 22
    • 13344278692 scopus 로고    scopus 로고
    • Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
    • (1996) Nature , vol.379 , pp. 349-353
    • Liston, P.1
  • 23
    • 0024546509 scopus 로고
    • The scanning model for translation: An update
    • (1989) J Cell Biol , vol.108 , pp. 229-241
    • Kozak, M.1
  • 25
    • 0023720048 scopus 로고
    • Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
    • (1988) Nature , vol.334 , pp. 320-325
    • Pelletier, J.1    Sonenberg, N.2
  • 31
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 32
    • 0034616942 scopus 로고    scopus 로고
    • Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
    • (2000) Cell , vol.102 , pp. 43-53
    • Verhagen, A.M.1
  • 35
    • 0034700491 scopus 로고    scopus 로고
    • Structural basis of IAP recognition by Smac/DIABLO
    • (2000) Nature , vol.408 , pp. 1008-1012
    • Wu, G.1
  • 36
    • 0034700495 scopus 로고    scopus 로고
    • Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
    • (2000) Nature , vol.408 , pp. 1004-1008
    • Liu, Z.1
  • 37
    • 0033521529 scopus 로고    scopus 로고
    • XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
    • (1999) Embo J , vol.18 , pp. 179-187
    • Yamaguchi, K.1
  • 40
    • 0034004126 scopus 로고    scopus 로고
    • TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development
    • (2000) Mol Cell Biol , vol.20 , pp. 3015-3026
    • Takatsu, Y.1
  • 41
    • 0033564780 scopus 로고    scopus 로고
    • Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus
    • (1999) J Neurosci , vol.19 , pp. 5026-5033
    • Xu, D.1
  • 43
    • 17144438370 scopus 로고    scopus 로고
    • Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
    • (2000) Clin Cancer Res , vol.6 , pp. 1796-1803
    • Tamm, I.1
  • 45
    • 0035831021 scopus 로고    scopus 로고
    • Structural basis of caspase-7 inhibition by XIAP
    • (2001) Cell , vol.104 , pp. 769-780
    • Chai, J.1
  • 46
    • 0035831022 scopus 로고    scopus 로고
    • Structural basis of caspase inhibition by XIAP. Differential roles of the linker versus the BIR domain
    • (2001) Cell , vol.104 , pp. 781-790
    • Huang, Y.1
  • 47
    • 0035831019 scopus 로고    scopus 로고
    • Structural basis for the inhibition of caspase-3 by XIAP
    • (2001) Cell , vol.104 , pp. 791-800
    • Riedl, S.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.